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Hirayoshi, Kazunori

Institute for Life and Medical Sciences (LiMe) Senior Lecturer/ Junior Associate Professor

Hirayoshi, Kazunori
list
    Last Updated :2022/09/09

    Basic Information

    Affiliated programs (koza)

    • Graduate School of Medicine, 医学専攻 細胞機能調節学, 講師
    • Graduate School of Medicine, 医科学専攻 細胞機能調節学, 講師
    • Graduate School of Science, 生物科学専攻 生物物理学(分子細胞生物学), 講師

    Professional Memberships

    • 日本生化学会
    • 日本分子生物学会
    • 日本細胞生物学会

    Academic Degree

    • 理学修士(甲南大学)
    • 医学博士(京都大学)

    Academic Resume (Graduate Schools)

    • 甲南大学, 大学院自然科学研究科修士課程, 修了
    • 京都大学, 大学院医学研究科博士課程, 修了

    Academic Resume (Undergraduate School/Majors)

    • Konan Univrcity, 理学部生物学科, 卒業

    High School

    • High School

      大阪星光学院

    Language of Instruction

    • English

    ID,URL

    researchmap URL

    list
      Last Updated :2022/09/09

      Research

      Research Topics, Overview of the research

      • Research Topics

        Analysis of general transcription mechanism
        Appplication of RNA aptamer
      • Overview of the research

        We are focusing on two major items. 1)the investigation of eukaryotic gene expression mechanisms and 2) the functional analysis of collagen molecules using RNA aptamers, artificial RNA molecules selected from random RNA pools, as target-specific inhibitors.

      Research Interests

      • 分子生物学
      • 細胞生物学
      • Molecular Biology
      • Cell Biology

      Research Areas

      • Life sciences, Cell biology
      • Life sciences, Molecular biology

      Papers

      • MONOCLONAL-ANTIBODY SPECIFICALLY REACTING AGAINST 73-KILODALTON HEAT-SHOCK COGNATE PROTEIN - POSSIBLE EXPRESSION ON MAMMALIAN-CELL SURFACE
        N TSUBOI; M ISHIKAWA; Y TAMURA; S TAKAYAMA; H TOBIOKA; A MATSUURA; K HIRAYOSHI; K NAGATA; N SATO; K KIKUCHI
        HYBRIDOMA, Oct. 1994, Peer-reviewed
      • ANOTHER MECHANISM FOR THE DEFECT IN TYPE-III COLLAGEN ACCUMULATION IN EHLERS-DANLOS SYNDROME TYPE-IV - INCREASED INTRACELLULAR DEGRADATION OF THE PROCOLLAGEN
        A UTANI; T TANAKA; C NISHIGORI; Y MIYACHI; K DANNO; S IMAMURA; M HOSOKAWA; T TAKEDA; K HIRAYOSHI; K NAGATA
        LABORATORY INVESTIGATION, Aug. 1990, Peer-reviewed
      • Perturbation of discrete sites on a single protein domain with RNA aptamers: Targeting of different sides of the TATA-binding protein (TBP)
        Ken I. Hohmura; Hua Shi; Kazunori Hirayoshi
        Bioscience, Biotechnology and Biochemistry, 2013, Peer-reviewed
      • Functional analysis of GAGA factor in transcription by RNA aptam
        Hohmuram K; Hirayoshi K
        20th IUBMBinternational Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress 2006 6.18-23 Kyoto, 2006, Peer-reviewed
      • Cultured murine dermal fibroblast-like cells from senescence-accelerated mice as in vitro models for higher oxidative stress due to mitochondrial alterations
        Y Chiba; Y Yamashita; M Ueno; H Fujisawa; K Hirayoshi; K Hohmura; H Tomimoto; Akiguchi, I; M Satoh; A Shimada; M Hosokawa
        JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, Sep. 2005, Peer-reviewed
      • Different adaptive traits to cold exposure in young senescence-accelerated mice
        Y Yamashita; Y Chiba; C Xia; K Hirayoshi; M Satoh; Y Saitoh; A Shimada; E Nakamura; M Hosokawa
        BIOGERONTOLOGY, Mar. 2005, Peer-reviewed
      • Characterization of multiple members of the HSP70 family in platyfish culture cells: Molecular evolution of stress protein HSP70 in vertebrates
        M Yamashita; K Hirayoshi; K Nagata
        GENE, Jul. 2004, Peer-reviewed
      • Mitochondrial alterations and a higher oxidative status in cultured fibroblast-like cells from senescence-accelerated mice
        Y Chiba; Y Yamashita; K Hirayoshi; M Ueno; H Fujisawa; T Matsushita; K Kogishi; Akiguchi, I; M Satoh; A Shimada; M Hosokawa
        SENESCENCE-ACCELERATED MOUSE (SAM): AN ANIMAL MODEL OF SENESCENCE, 2004, Peer-reviewed
      • The Kruppel-like factor Zf9 and proteins in the Sp1 family regulate the expression of HSP47, a collagen-specific molecular chaperone
        K Yasuda; K Hirayoshi; H Hirata; H Kubota; N Hosokawa; K Nagata
        JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2002, Peer-reviewed
      • Expression of N-deacetylase/sulfotransferase and 3-O-sulfotransferase in rat alveolar type II cells
        ZY Li; K Hirayoshi; Y Suzuki
        AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Aug. 2000, Peer-reviewed
      • Separate cis-acting DNA elements control cell type- and tissue-specific expression of collagen binding molecular chaperone HSP47
        H Hirata; Yamamura, I; K Yasuda; A Kobayashi; N Tada; M Suzuki; K Hirayoshi; N Hosokawa; K Nagata
        JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 1999, Peer-reviewed
      • Nuclear run-on assays: Assessing transcription by measuring density of engaged RNA polymerases
        K Hirayoshi; JT Lis
        CHROMATIN, 1999, Peer-reviewed
      • Direct cloning of DNA that interacts in vivo with a specific protein: application to RNA polymerase II and sites of pausing in Drosophila
        A Law; K Hirayoshi; T O'Brien; JT Lis
        NUCLEIC ACIDS RESEARCH, Feb. 1998, Peer-reviewed
      • Intracellular interaction of collagen-specific stress protein HSP47 with newly synthesized procollagen
        M Satoh; K Hirayoshi; SI Yokota; N Hosokawa; K Nagata
        JOURNAL OF CELL BIOLOGY, Apr. 1996, Peer-reviewed
      • Transcriptional regulation of the vimentin-encoding gene in mouse myeloid leukemia M1 cells
        N Nakamura; M Shida; K Hirayoshi; K Nagata
        GENE, Dec. 1995, Peer-reviewed
      • HSF ACCESS TO HEAT-SHOCK ELEMENTS IN-VIVO DEPENDS CRITICALLY ON PROMOTER ARCHITECTURE DEFINED BY GAGA FACTOR, TFIID AND RNA-POLYMERASE-II BINDING-SITES
        LS SHOPLAND; K HIRAYOSHI; M FERNANDES; JT LIS
        GENES & DEVELOPMENT, Nov. 1995, Peer-reviewed
      • INTERACTIONS BETWEEN COLLAGEN-BINDING STRESS PROTEIN HSP47 AND COLLAGEN - ANALYSIS OF KINETIC-PARAMETERS BY SURFACE-PLASMON RESONANCE BIOSENSOR
        T NATSUME; T KOIDE; S YOKOTA; K HIRAYOSHI; K NAGATA
        JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 1994, Peer-reviewed
      • COEXPRESSION OF THE COLLAGEN-BINDING STRESS PROTEIN HSP47 GENE AND THE ALPHA-1(I) AND ALPHA-1(III) COLLAGEN GENES IN CARBON TETRACHLORIDE-INDUCED RAT-LIVER FIBROSIS
        H MASUDA; M FUKUMOTO; K HIRAYOSHI; K NAGATA
        JOURNAL OF CLINICAL INVESTIGATION, Dec. 1994, Peer-reviewed
      • PREFERENTIAL LOCALIZATION OF HEAT-SHOCK PROTEIN-47 IN DILATED ENDOPLASMIC-RETICULUM OF CHICKEN CHONDROCYTES
        K KAMBE; A YAMAMOTO; T YOSHIMORI; K HIRAYOSHI; R OGAWA; Y TASHIRO
        JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, Jul. 1994, Peer-reviewed
      • 2 COLLAGEN-BINDING PROTEINS, OSTEONECTIN AND HSP47, ARE COORDINATELY INDUCED IN TRANSFORMED KERATINOCYTES BY HEAT AND OTHER STRESSES
        H KUDO; K HIRAYOSHI; Y KITAGAWA; S IMAMURA; K NAGATA
        EXPERIMENTAL CELL RESEARCH, Jun. 1994, Peer-reviewed
      • ENHANCEMENT OF DIFFERENTIATION INDUCTION OF MOUSE MYELOMONOCYTIC LEUKEMIC-CELLS BY EXTRACELLULAR ATP
        M YAMAGUCHI; K HIRAYOSHI; M OKUMA; K NAGATA
        JOURNAL OF CELLULAR PHYSIOLOGY, Jun. 1994, Peer-reviewed
      • ALTERNATIVE 5' SPLICE-SITE SELECTION INDUCED BY HEAT-SHOCK
        H TAKECHI; N HOSOKAWA; K HIRAYOSHI; K NAGATA
        MOLECULAR AND CELLULAR BIOLOGY, Jan. 1994, Peer-reviewed
      • Detection of cell surface 73KDa heat shock cognate protein by a newly-developed monoclonal antibody
        平芳 一法
        Hybridoma,13/5,373-381, 1994, Peer-reviewed
      • STRUCTURE OF THE GENE ENCODING THE MOUSE 47-KDA HEAT-SHOCK PROTEIN (HSP47)
        N HOSOKAWA; H TAKECHI; S YOKOTA; K HIRAYOSHI; K NAGATA
        GENE, Apr. 1993, Peer-reviewed
      • MODULATION OF THE PHOSPHORYLATION OF GLUCOSE-REGULATED PROTEIN, GRP78, BY TRANSFORMATION AND INHIBITION OF GLYCOSYLATION
        M SATOH; A NAKAI; Y SOKAWA; K HIRAYOSHI; K NAGATA
        EXPERIMENTAL CELL RESEARCH, Mar. 1993, Peer-reviewed
      • DOWN-REGULATION OF INTERLEUKIN-6 RECEPTORS OF MOUSE MYELOMONOCYTIC LEUKEMIC-CELLS BY LEUKEMIA INHIBITORY FACTOR
        M YAMAGUCHI; M MICHISHITA; K HIRAYOSHI; K YASUKAWA; M OKUMA; K NAGATA
        JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 1992, Peer-reviewed
      • QUERCETIN, AN INHIBITOR OF HEAT-SHOCK PROTEIN-SYNTHESIS, INHIBITS THE ACQUISITION OF THERMOTOLERANCE IN A HUMAN COLON-CARCINOMA CELL-LINE
        M KOISHI; N HOSOKAWA; M SATO; A NAKAI; K HIRAYOSHI; M HIRAOKA; M ABE; K NAGATA
        JAPANESE JOURNAL OF CANCER RESEARCH, Nov. 1992, Peer-reviewed
      • INHIBITION OF THE ACTIVATION OF HEAT-SHOCK FACTOR INVIVO AND INVITRO BY FLAVONOIDS
        N HOSOKAWA; K HIRAYOSHI; H KUDO; H TAKECHI; A AOIKE; K KAWAI; K NAGATA
        MOLECULAR AND CELLULAR BIOLOGY, Aug. 1992, Peer-reviewed
      • MOLECULAR-CLONING OF A MOUSE 47-KDA HEAT-SHOCK PROTEIN (HSP47), A COLLAGEN-BINDING STRESS PROTEIN, AND ITS EXPRESSION DURING THE DIFFERENTIATION OF F9 TERATOCARCINOMA CELLS
        H TAKECHI; K HIRAYOSHI; A NAKAI; H KUDO; S SAGA; K NAGATA
        EUROPEAN JOURNAL OF BIOCHEMISTRY, Jun. 1992, Peer-reviewed
      • PURIFICATION AND CHARACTERIZATION OF A VIMENTIN-SPECIFIC PROTEASE IN MOUSE MYELOID-LEUKEMIA CELLS - REGULATION DURING DIFFERENTIATION AND IDENTITY WITH CATHEPSIN-G
        N NAKAMURA; A TSURU; K HIRAYOSHI; K NAGATA
        EUROPEAN JOURNAL OF BIOCHEMISTRY, May 1992, Peer-reviewed
      • INVOLVEMENT OF THE STRESS PROTEIN HSP47 IN PROCOLLAGEN PROCESSING IN THE ENDOPLASMIC-RETICULUM
        A NAKAI; M SATOH; K HIRAYOSHI; K NAGATA
        JOURNAL OF CELL BIOLOGY, May 1992, Peer-reviewed
      • QUERCETIN, A BIOFLAVONOID, INHIBITS THE INCREASE OF HUMAN MULTIDRUG RESISTANCE GENE (MDR1) EXPRESSION CAUSED BY ARSENITE
        N KIOKA; N HOSOKAWA; T KOMANO; K HIRAYOSHI; K NAGATA; K UEDA
        FEBS LETTERS, Apr. 1992, Peer-reviewed
      • EFFECTS OF TYPE-BETA-1 TRANSFORMING GROWTH-FACTOR ON THE PROLIFERATION AND DIFFERENTIATION OF MOUSE MYELOMONOCYTIC LEUKEMIA-CELLS (M1)
        M MICHISHITA; K HIRAYOSHI; A TSURU; N NAKAMURA; Y YOSHIDA; M OKUMA; K NAGATA
        EXPERIMENTAL CELL RESEARCH, Sep. 1991, Peer-reviewed
      • HSP47 - A TISSUE-SPECIFIC, TRANSFORMATION-SENSITIVE, COLLAGEN-BINDING HEAT-SHOCK PROTEIN OF CHICKEN-EMBRYO FIBROBLASTS
        K HIRAYOSHI; H KUDO; H TAKECHI; A NAKAI; A IWAMATSU; KM YAMADA; K NAGATA
        MOLECULAR AND CELLULAR BIOLOGY, Aug. 1991, Peer-reviewed
      • BOTH D-FACTOR LIF AND IL-6 INHIBIT THE DIFFERENTIATION OF MOUSE TERATOCARCINOMA F9 CELLS
        K HIRAYOSHI; A TSURU; M YAMASHITA; M TOMIDA; Y YAMAMOTOYAMAGUCHI; K YASUKAWA; M HOZUMI; DV GOEDDEL; K NAGATA
        FEBS LETTERS, May 1991, Peer-reviewed
      • PHOSPHORYLATION OF THE STRESS PROTEIN HSP27 IS AN EARLY EVENT IN MURINE MYELOMONOCYTIC LEUKEMIC-CELL DIFFERENTIATION INDUCED BY LEUKEMIA INHIBITORY FACTOR D-FACTOR
        M MICHISHITA; M SATOH; M YAMAGUCHI; K HIRAYOSHI; M OKUMA; K NAGATA
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, May 1991, Peer-reviewed
      • IDENTIFICATION OF THE ATP-BINDING HEAT-INDUCIBLE PROTEIN OF MR=37,000 AS GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
        A NAKAI; M SATOH; K HIRAYOSHI; K NAGATA
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 1991, Peer-reviewed
      • FLAVONOIDS INHIBIT THE EXPRESSION OF HEAT-SHOCK PROTEINS
        N HOSOKAWA; K HIRAYOSHI; A NAKAI; Y HOSOKAWA; N MARUI; M YOSHIDA; T SAKAI; H NISHINO; A AOIKE; K KAWAI; K NAGATA
        CELL STRUCTURE AND FUNCTION, Dec. 1990, Peer-reviewed
      • NOVEL ATP-BINDING HEAT-INDUCIBLE PROTEIN OF MR = 37,000 THAT IS SENSITIVE TO TRANSFORMATION IN BALB 3T3 CELLS
        A NAKAI; C HIRAYAMA; K OHTSUKA; K HIRAYOSHI; K NAGATA
        JOURNAL OF CELLULAR PHYSIOLOGY, Jun. 1990, Peer-reviewed
      • REGULATION OF THE EXPRESSION OF VIMENTIN GENE DURING THE DIFFERENTIATION OF MOUSE MYELOID-LEUKEMIA CELLS
        A TSURU; N NAKAMURA; E TAKAYAMA; Y SUZUKI; K HIRAYOSHI; K NAGATA
        JOURNAL OF CELL BIOLOGY, May 1990, Peer-reviewed
      • TRANSFORMATION OF BALB/3T3 CELLS BY SIMIAN VIRUS-40 CAUSES A DECREASED SYNTHESIS OF A COLLAGEN-BINDING HEAT-SHOCK PROTEIN (HSP47)
        A NAKAI; K HIRAYOSHI; K NAGATA
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 1990, Peer-reviewed
      • THE TRANSFORMATION-SENSITIVE HEAT-SHOCK PROTEIN (HSP47) BINDS SPECIFICALLY TO FETUIN
        A NAKAI; K HIRAYOSHI; S SAGA; KM YAMADA; K NAGATA
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Oct. 1989, Peer-reviewed
      • Changes in the intermediate filaments, vimentin, during the differentiation of mouse myeloid leukemia cells
        K. Nagata; A. Tsuru; N. Nakamura; E. Takayama; Y. Suzuki; K. Hirayoshi
        Cell Structure and Function, 1989, Peer-reviewed
      • BIOSYNTHESIS OF A NOVEL TRANSFORMATION-SENSITIVE HEAT-SHOCK PROTEIN THAT BINDS TO COLLAGEN - REGULATION BY MESSENGER-RNA LEVELS AND INVITRO SYNTHESIS OF A FUNCTIONAL PRECURSOR
        K NAGATA; K HIRAYOSHI; M OBARA; S SAGA; KM YAMADA
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jun. 1988, Peer-reviewed
      • EFFECT OF THE RECOMBINANT VACCINIA VIRUSES THAT EXPRESS HTLV-I ENVELOPE GENE ON HTLV-I INFECTION
        H SHIDA; T TOCHIKURA; T SATO; T KONNO; K HIRAYOSHI; M SEKI; Y ITO; M HATANAKA; Y HINUMA; M SUGIMOTO; F TAKAHASHINISHIMAKI; T MARUYAMA; K MIKI; K SUZUKI; M MORITA; H SASHIYAMA; M HAYAMI
        EMBO JOURNAL, Nov. 1987, Peer-reviewed
      • IMMUNOGLOBULIN HEAVY-CHAIN GENE DIVERSIFICATION IN THE LONG-TERM BONE-MARROW CULTURE OF NORMAL MICE AND MICE WITH SEVERE COMBINED IMMUNODEFICIENCY
        K HIRAYOSHI; SI NISHIKAWA; T KINA; M HATANAKA; S HABU; T NOMURA; Y KATSURA
        EUROPEAN JOURNAL OF IMMUNOLOGY, Jul. 1987, Peer-reviewed
      • EXPRESSION OF THE C-MYC GENE IN HUMAN GASTROINTESTINAL MALIGNANCIES
        K TSUBOI; K HIRAYOSHI; K TAKEUCHI; H SABE; Y SHIMADA; G OHSHIO; T TOBE; M HATANAKA
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jul. 1987, Peer-reviewed
      • EXPRESSION OF A PROVIRUS OF HUMAN T-CELL LEUKEMIA-VIRUS TYPE-I BY DNA TRANSFECTION
        K MORI; H SABE; H SIOMI; T IINO; A TANAKA; K TAKEUCHI; K HIRAYOSHI; M HATANAKA
        JOURNAL OF GENERAL VIROLOGY, Feb. 1987, Peer-reviewed
      • LIMITING DILUTION ANALYSIS OF THE STEM-CELLS FOR T-CELL LINEAGE
        Y KATSURA; T KINA; T AMAGAI; T TSUBATA; K HIRAYOSHI; Y TAKAOKI; T SADO; SI NISHIKAWA
        JOURNAL OF IMMUNOLOGY, Oct. 1986, Peer-reviewed
      • GENOMIC EXPRESSIONS OF HUMAN T-LYMPHOTROPIC VIRUS (HTLV-I)
        M HATANAKA; H SABE; A TANAKA; K MORI; H SIOMI; S NAM; Y ADACHI; S ITAMURA; K HIRAYOSHI
        AIDS RESEARCH, Dec. 1986, Peer-reviewed

      Misc.

      • IDENTIFICATION OF CIS-ELEMENTS AND TRANSCRIPTION FACTORS THAT REGULATE THE TISSUE SPECIFIC EXPRESSION OF HSP47
        Yasuda Kunihiko; Hirayoshi Kazunori; Hosokawa Nobuko; Nagata Kazuhiro
        Connective tissue, Apr. 2002
      • HSP47の組織特異的発現は2つのシスエレメントにより制御されている
        平田普三; 山村功; 安田邦彦; 小林明央; 多田昇弘; 鈴木操; 平芳一法; 細川暢子; 永田和宏
        日本細胞生物学会大会講演要旨集, 1999
      • コラーゲン特異的分子シャペロンHSP47のプロモーター解析
        平田普三; 山村功; 平芳一法; 細川暢子; 永田和宏
        日本分子生物学会年会プログラム・講演要旨集, Nov. 1998
      • TRANSCRIPTIONAL CONTROL OF THE EXPRESSION OF NOVEL HEAT-SHOCK PROTEIN (HSP47)
        K NAGATA; K HIRAYOSHI; S SAGA; M OBARA; KM YAMADA
        CELL STRUCTURE AND FUNCTION, Dec. 1987
      • DIFFERENTIATION OF THE TERATOCARCINOMA CELL F9 AND THE INDUCTION OF HEAT-SHOCK PROTEIN (HSP47)
        K HIRAYOSHI; K NAGATA
        CELL STRUCTURE AND FUNCTION, Dec. 1987
      • 転写開始複合体形成におけるクロマチンリモデリング因子の関与
        法邑賢一; 平芳一法
        ポスター3 転写開始複合体形成におけるクロマチンリモデリング因子の関与 法邑賢一、平芳一法(細胞機能調節学分野) 「再生医学・再生医療の先端融合的共同研究拠点」 平成24 年度学術講演会 開催日:2012 年12 月19 日(水), 2012, Peer-reviewed
      • RNA アプタマーを用いたGAF の機能解析
        法邑賢一; 平芳一法
        第53 回日本分子生物学会物学会年会, (2012.12.11-14.福岡), 2012, Peer-reviewed
      • 転写複合体形成過程におけるTBP/GAF 間相互作用の解析
        平芳一法; 法邑賢一
        第84 回日本遺伝学会大会 (2012.9.24-26.福岡), 2012, Peer-reviewed
      • Analyses of communication between GAF and TBP by RNA aptamers
        法邑 賢一; 平芳 一法
        京都大学再生医科学研究所 「再生医学・再生医療の先端融合的共同研究拠点」 平成23 年度 学術講演会 2011 年12 月26 日(月) ポスター3, 2011, Peer-reviewed
      • 転写初期段階におけるクロマチン関連因子を核とした因子間ネットワークの解明
        法邑賢一; 平芳一法
        京都大学再生医科学研究所 \n「再生医学・再生医療の先端融合的共同研究拠点」 \n平成22 年度学術講演会 \n開催日:2010 年12 月13 日(月) \n場所:芝蘭会館稲盛ホール, 2010, Peer-reviewed
      • PIC 形成過程におけるTBP/GAF 間相互作用の役割
        法邑賢一; 平芳一法
        .第32 回日本分子生物学会年会 (2009.12.9-12.横浜), 2009, Peer-reviewed
      • RNA アプタマーを用いた転写因子GAF の機能解析
        法邑賢一; 平芳一法
        第82 回日本生化学会大会(2009.10.21- 24.神戸), 2009, Peer-reviewed
      • RNA APTAMER AS A MOLECULAR TOOL FOR ANALYZING THE PROTEIN-PROTEIN INTERACTION
        Ken-ichi Hohmura; Kazunori Hirayoshi
        POSTER 12 International Symposium on Regenerative Medical Therapy (Institute for Frontier Medical Sciences, Kyoto University 2007 年9 月19 日(水)20 日(木), 2007, Peer-reviewed
      • 転写開始後におけるGAGA 因子の機能解析の解析
        法邑賢一; 平芳一法
        第30 回日本分子生物学会物学会年会 (2007.12.11.~15. 横浜), 2007, Peer-reviewed
      • The analysis of intra-molecular regulation of TBP by RNA aptamer
        平芳一法; 法邑賢一
        第78 回日本生化学会大会 ワークショップ「転写I」(2005. 10. 20.神戸), 20 Oct. 2005, Peer-reviewed
      • Involvements of GAGA factor in transcription analyzed by RNA aptamers
        法邑賢一; 平芳一法
        第78 回日本生化学会大会ワークショップ「転写I」(2005. 10. 20.神戸), 20 Oct. 2005, Peer-reviewed
      • TBP 特異的RNA アプタマーを用いた転写機構の解析
        平芳一法; 法邑賢一
        第28 回日本分子生物学会年会(2005. 12. 7. ~10.福岡), 2005, Peer-reviewed
      • 転写過程におけるGAGA 因子複合体の機能―RNA アプタマーを用いた解析―
        邑賢一; 平芳一法
        第28 回日 本分子生物学会年会(2005. 12. 7. ~10.福岡), 2005, Peer-reviewed
      • The analysis of transcription complex by RNA aptamer(1)Drosophila TBP as a target
        法邑賢一; 平芳一法
        第77 回 日本生化学会大会(2004.10.13.~16. 横浜), 13 Oct. 2004, Peer-reviewed
      • TBP 特異的RNA アプタマーを用いた転写調節機構の解析
        法邑賢一; 平芳一法
        第27 回日本分子生物学会年会 (2004.12.8.~11. 神戸), 2004, Peer-reviewed
      • ショウジョウバエGAGA 因子に結合するRNA アプタマーの解析
        平芳一法; 法邑賢一
        第27 回日本分子生物学会年会(2004.12.8.~11. 神戸), 2004, Peer-reviewed
      • RNA aptqamerによる転写複合体中因子の機能解析
        法邑 賢一; 平芳 一法
        第37回日本分子生物学会年会 (2014.11.25-27. 横浜

      Presentations

      • I型コラーゲンに対するRNAアプタマーの選別
        平芳 一法
        第41回日本分子生物学会年会, 28 Nov. 2018
      • RNAアプタマーによるショウジョウバエ転写因子GAFの機能解析
        平芳 一法
        06 Dec. 2017

      External funds: Kakenhi

      • Selection of RNA aptamer against collagen and apply to new drug discovery
        Grant-in-Aid for Challenging Research (Exploratory)
        Kyoto University
        Kazunori Hirayoshi
        From 30 Jun. 2017, To 31 Mar. 2019, Project Closed
        RNAアプタマー;コラーゲン;RNA aptamer
      • Transplantation of co-aggregates of islet cells and immune suppressor cells
        Grant-in-Aid for Scientific Research (A)
        Kyoto University
        Hiroo IWATA
        From 01 Apr. 2012, To 31 Mar. 2015, Project Closed
        ランゲルハンス氏島;膵島;制御性T細胞;糖尿病;血糖値;移植;皮下移植;拒絶反応
      • The analysis of general transcription machinary by RNA aptamer
        Grant-in-Aid for Scientific Research (C)
        KYOTO UNIVERSITY
        Kazunori HIRAYOSHI
        From 01 Apr. 2000, To 31 Mar. 2002, Project Closed
        RNA aptamer;初期転写複合体;表面プラズモン共鳴;SELEX;TBP;Paused polymerase;基本転写因子;TAF60;ショウジョウバエ, RNA aptamer;pre-initiation complex;surface plasmon resonance;SELEX;TBP
      • Regulation of phenotype and gene expression in alveolar epithelial cells
        Grant-in-Aid for Scientific Research (C)
        KYOTO UNIVERSITY
        Yasuhiro SUZUKI
        From 01 Apr. 2000, To 31 Mar. 2002, Project Closed
        肺胞II型細胞;分化転換;硫酸転移酵素;プロテオグリカン;細胞伸展;肺障害;MT-MMP;肺傷害;肺胞上皮細胞;遺伝子発現;ヘパラン硫酸;ハービマイシンA;リチウム, type II cell;transdifferentiation;sulfotransferase;proteoglycan;cell spreading;lung damage;MT-MMP
      • コラーゲン特異的分予シャペロンHSP47の構造と機能
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        永田 和宏
        From 01 Apr. 1999, To 31 Mar. 2001, Project Closed
        HSP47;コラーゲン;semi-permeabilized cell;ノックアウトマウス;分子シャペロン;結晶解析
      • The analysis of the function and establishment mechnism of paused polymerase
        Grant-in-Aid for Scientific Research (C)
        KYOTO UNIVERSITY
        Kazunori HIRAYOSHI
        From 01 Apr. 1998, To 31 Mar. 2000, Project Closed
        転写調節;ショウジョウバエ;RNA polymerase II;Paused polymerase;HSP70;TATA;DPE;GAGA;GAGA因子, Transcriptional regulation;Drosophila;RNA polymerasell;Paused polymerase;HSP70;TATA;DPE;GAGA
      • ストレス蛋白質HSP47の転写調節機構の解明
        Grant-in-Aid for General Scientific Research (C)
        Kyoto University
        平芳 一法
        From 01 Apr. 1993, To 31 Mar. 1994, Project Closed
        ストレス蛋白質;コラーゲン;transtection
      • コラーゲン特異的ストレス蛋白質HSP47の機能と発現
        Grant-in-Aid for Scientific Research on Priority Areas
        Kyoto University
        平芳 一法
        From 01 Apr. 1993, To 31 Mar. 1994, Project Closed
        ストレス蛋白質;Breferdin A;Monensin;Bafilomycin A1;コラーゲン
      • Studies on the molecular mechanism of heat shock protein 47.
        Grant-in-Aid for Overseas Scientific Survey.
        Kyoto University
        Akira NAKAI
        From 01 Apr. 1993, To 31 Mar. 1994, Project Closed
        熱ショック蛋白質;ストレス蛋白質;細胞内輸送;コラーゲン;分子シャペロン;構造解析;分子間結合;分子生物学, Heat Shock Protein;Stress Protein;Molecular Chaperone;Structual Analysis;Collagen;Molecular Biology;Intracellnlar transport;Intermolecular Association
      • コラーゲン特異的ストレス蛋白質HSP47の発現調節
        Grant-in-Aid for General Scientific Research (C)
        Kyoto University
        平芳 一法
        From 01 Apr. 1992, To 31 Mar. 1993, Project Closed
        ストレス蛋白質;コラーゲン;分子シャペロン
      • The role of stress proteins in the protein biosynthesis.
        Grant-in-Aid for international Scientific Research
        Kyoto University
        Kazuhiro NAGATA
        From 01 Apr. 1992, To 31 Mar. 1994, Project Closed
        ストレス蛋白質;熱ショック転写因子;分子シャペロン;コラーゲン;小胞体, Stress protein;Heat shock transcription factor;Molecular Chaperone
      • コラ-ゲン特異的ストレス蛋白質HSP47の構造と機能
        Grant-in-Aid for General Scientific Research (C)
        Kyoto University
        平芳 一法
        From 01 Apr. 1991, To 31 Mar. 1992, Project Closed
        ストレス蛋白質;コラ-ゲン;分子シャペロン
      • 温熱耐性克服のための熱ショック蛋白質の基礎的研究
        Grant-in-Aid for Cancer Research
        Kyoto University
        永田 和宏
        From 01 Apr. 1988, To 31 Mar. 1989, Project Closed
        hsp47;熱ショック蛋白質(ヒートショックプロテイン);トランスフォーメーション;コラーゲン

      External funds: others

      • The function and regulation of collagen specific shaperone HSP47
      • The function and mechanism of generating paused polymerase
      • The analysis of transcription mechanism by RNA aptamer
      list
        Last Updated :2022/09/09

        Education

        Teaching subject(s)

        • From Apr. 2012, To Mar. 2013
          gene expression101
          Spring, 全学共通科目
        • From Apr. 2013, To Mar. 2014
          gene expression101
          Spring, 全学共通科目
        • From Apr. 2014, To Mar. 2015
          gene expression101
          Spring, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          gene expression 101
          Spring, 全学共通科目
        • From Apr. 2016, To Mar. 2017
          ILAS Seminar
          Spring, 全学共通科目
        • From Apr. 2017, To Mar. 2018
          ILAS Seminar
          Spring, 全学共通科目
        • From Apr. 2018, To Mar. 2019
          ILAS Seminar
          Spring, 全学共通科目
        • From Apr. 2019, To Mar. 2020
          ILAS Seminar
          Spring, 全学共通科目
        • From Apr. 2020, To Mar. 2021
          ILAS Seminar :gene expression 101 [How do we regulate the gene expression?]
          Spring, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          ILAS Seminar :gene expression 101 [How do we regulate the gene expression?]
          Spring, 全学共通科目

        Part-time lecturer

        • From 01 Apr. 2019, To 22 Sep. 2019
          京都光華女子大学
        list
          Last Updated :2022/09/09

          Administration

          School management (title, position)

          • 放射線障害予防小委員会 委員
          • From 01 Apr. 2016, To 31 Mar. 2018
            有機廃液情報管理小委員会委員
          • 特別管理産業廃棄物管理責任者

          Faculty management (title, position)

          • To 01 May 2021
            共同利用機器等委員会 委員
          • From 01 Oct. 2016
            化学物質管理委員会 委員
          • From 01 Jun. 2017
            施設整備委員会 委員
          • To 30 Apr. 2021
            共同利用機器等委員会 委員長
          • 安全衛生委員会 委員
          • 図書委員会 委員
          • To 31 Mar. 2023
            医学図書館連絡委員
          • From 01 Oct. 2016, To Sep. 2019
            放射線障害防止委員会 委員
          • 共同機器室運営委員会 委員
          • From 01 Oct. 2016
            (旧再生研)共同機器室運営委員会 委員長

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