Shin, Hye-won(Graduate School of Pharmaceutical Sciences, Division of Pharmaceutical Sciences) | Activity Database on Education and Research, Kyoto University

Shin, Hye-won

Graduate School of Pharmaceutical Sciences, Division of Pharmaceutical Sciences Associate Professor

Last Updated :2022/06/24

Basic Information

Faculty

薬学部

Concurrent Affiliation

Graduate School of Biostudies, 生命科学研究科 Global Frontier in Life Science A

Graduate School of Pharmaceutical Sciences, 薬学研究科連携助教

Graduate School of Pharmaceutical Sciences, 薬学研究科基礎物理化学特論Ⅱ

Professional Memberships

Korean Society for Molecular and Cellular Biology

American Society for Biochemistry and Molecular Biology

The American Society for Cell Biology

日本薬学会

日本生化学会

日本細胞生物学会

Academic Degree

Master of Science(Kyungpook National University)

PhD(University of Tsukuba)

Language of Instruction

Japanese

English

Korean

Last Updated :2022/06/24

Research

Research Topics, Overview of the research

Research Topics
Biological membrane dynamics in cell physiology
Overview of the research
Lipid bilayers, including those of the plasma membrane and the membrane-enclosed compartments along the secretory and endocytic pathways, exhibit asymmetric lipid distributions. The asymmetric distributions are generated and regulated by flippases (P4-ATPases), floppases (ABC transporters), and scramblases. Spatio-temporal regulation of the lipid asymmetry is critical for many biological processes, such as apoptotic cell death, platelet coagulation, fusion of muscle cells, cytokinesis, cell migration, sperm capacitation and intracellular membrane trafficking. However, the molecular mechanism is largely unknown. We aim to elucidate that how spatio-temporal lipid composition changes are regulated and how such changes regulate cellular function and further homeostasis of organisms.

Research Areas

Life sciences, Cell biology

Papers

The interaction of ATP11C-b with ezrin contributes to its polarized localization
Hiroki Inoue; Hiroyuki Takatsu; Asuka Hamamoto; Masahiro Takayama; Riki Nakabuchi; Yumeka Muranaka; Tsukasa Yagi; Kazuhisa Nakayama; Hye-Won Shin
Journal of Cell Science, 16 Sep. 2021, Peer-reviewed, Corresponding author

The N- or C-terminal cytoplasmic regions of P4-ATPases determine their cellular localization.
Sayuri Okamoto; Tomoki Naito; Ryo Shigetomi; Yusuke Kosugi; Kazuhisa Nakayama; Hiroyuki Takatsu; Hye-Won Shin
Molecular biology of the cell, 01 Sep. 2020, Peer-reviewed, Corresponding author

Phosphatidylserine exposure in living cells
Hye-Won Shin; Hiroyuki Takatsu
Critical Reviews in Biochemistry and Molecular Biology, 03 Mar. 2020, Peer-reviewed, Corresponding author

ATPase reaction cycle of P4‐ATPases affects their transport from the endoplasmic reticulum
Takuya Tone; Kazuhisa Nakayama; Hiroyuki Takatsu; Hye‐Won Shin
FEBS Letters, Feb. 2020, Peer-reviewed, Corresponding author

The cytoplasmic C-terminal region of the ATP11C variant determines its localization at the polarized plasma membrane
Masahiro Takayama; Hiroyuki Takatsu; Asuka Hamamoto; Hiroki Inoue; Tomoki Naito; Kazuhisa Nakayama; Hye-Won Shin
Journal of Cell Science, 01 Sep. 2019, Peer-reviewed, Corresponding author

Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs
Bartholomew P. Roland; Tomoki Naito; Jordan T. Best; Cayetana Arnaiz-Yépez; Hiroyuki Takatsu; Roger J. Yu; Hye-Won Shin; Todd R. Graham
Journal of Biological Chemistry, 08 Feb. 2019, Peer-reviewed

Phospholipid-flipping activity of P4-ATPase drives membrane curvature
Naoto Takada; Tomoki Naito; Takanari Inoue; Kazuhisa Nakayama; Hiroyuki Takatsu; Hye-Won Shin
EMBO Journal, 02 May 2018, Peer-reviewed, Corresponding author

Substrates of P4-ATPases: beyond aminophospholipids (phosphatidylserine and phosphatidylethanolamine)
Hye-Won Shin; Hiroyuki Takatsu
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Peer-reviewed, Corresponding author

Uptake of glucose-conjugated MGMT inhibitors in cancer cells: role of flippases and type IV P-type ATPases
Karl-Heinz Tomaszowski; Nadja Hellmann; Viviane Ponath; Hiroyuki Takatsu; Hye-Won Shin; Bernd Kaina
Scientific Reports, Dec. 2017, Peer-reviewed

Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation
Hiroyuki Takatsu; Masahiro Takayama; Tomoki Naito; Naoto Takada; Kazuya Tsumagari; Yasushi Ishihama; Kazuhisa Nakayama; Hye-Won Shin
NATURE COMMUNICATIONS, Nov. 2017, Peer-reviewed, Corresponding author

Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane (vol 289, pg 33543, 2014)
Hiroyuki Takatsu; Gaku Tanaka; Katsumori Segawa; Jun Suzuki; Shigekazu Nagata; Kazuhisa Nakayama; Hye-Won Shin
JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2016, Peer-reviewed, Corresponding author

The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane
Yoshiki Tanaka; Natsuki Ono; Takahiro Shima; Gaku Tanaka; Yohei Katoh; Kazuhisa Nakayama; Hiroyuki Takatsu; Hye-Won Shin
Molecular biology of the cell, 2016, Peer-reviewed, Corresponding author

Alteration of transbilayer phospholipid compositions is involved in cell adhesion, cell spreading, and focal adhesion formation
Rie Miyano; Takashi Matsumoto; Hiroyuki Takatsu; Kazuhisa Nakayama; Hye-Won Shin
FEBS letters, 2016, Peer-reviewed, Corresponding author

Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis
Ayako Hanai; Minako Ohgi; Chikako Yagi; Tomoko Ueda; Hye-Won Shin; Kazuhisa Nakayama
Journal of biochemistry, 2016, Peer-reviewed

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner (vol 286, pg 38159, 2011)
Hiroyuki Takatsu; Keiko Baba; Takahiro Shima; Hiroyuki Umino; Utako Kato; Masato Umeda; Kazuhisa Nakayama; Hye-Won Shin
JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 2015, Peer-reviewed, Corresponding author

ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells
Naoto Takada; Hiroyuki Takatsu; Rie Miyano, Kazuhisa Nakayama; Hye-Won Shin
Journal of lipid research, 2015, Peer-reviewed, Corresponding author

Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics
Tomoki Naito; Hiroyuki Takatsu; Rie Miyano; Naoto Takada; Kazuhisa Nakayama; Hye-Won Shin
The Journal of biological chemistry, 2015, Peer-reviewed, Corresponding author

SNAP23/25 and VAMP2 mediate exocytic event of transferrin receptor-containing recycling vesicles
Keiji Kubo; Minako Kobayashi; Shohei Nozaki; Chikako Yagi; Kiyotaka Hatsuzawa; Yohei Katoh; Hye-Won Shin; Senye Takahashi; Kazuhisa Nakayama
Biology open, 2015, Peer-reviewed

COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions
Kouhei Takashima; Akina Saitoh; Teruki Funabashi; Shohei Hirose, Chikako Yagi; Shohei Nozaki; Ryuichiro Sato; Hye-Won Shin; Kazuhisa Nakayama
Journal of cell science, 2015, Peer-reviewed

Phospholipid Flippase Activities and Substrate Specificities of Human Type IV P-type ATPases Localized to the Plasma Membrane
Hiroyuki Takatsu; Gaku Tanaka; Katsumori Segawa; Jun Suzuki; Shigekazu Nagata; Kazuhisa Nakayama; Hye-Won Shin
JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2014, Peer-reviewed, Corresponding author

ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus
Waka Nakai; Yumika Kondo; Akina Saitoh; Tomoki Naito; Kazuhisa Nakayama; Hye-Won Shin
Molecular Biology of the Cell, 15 Aug. 2013, Peer-reviewed, Corresponding author

Mitosis-coupled, microtubule-dependent clustering of endosomal vesicles around centrosomes
Hiroyuki Takatsu; Yohei Katoh; Tomoko Ueda; Satoshi Waguri; Takashi Murayama; Senye Takahashi; Hye-Won Shin; Kazuhisa Nakayama
Cell structure and function, 2013, Peer-reviewed

EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis
Tomoko Ueda; Ayako Hanai; Tomomi Takei; Keiji Kubo; Minako Ohgi; Hiroyuki Sakagami; Senye Takahashi; Hye-Won Shin; Kazuhisa Nakayama
FEBS letters, 2013, Peer-reviewed

Rab11 regulates exocytosis of recycling vesicles at the plasma membrane
Senye Takahashi; Keiji Kubo; Satoshi Waguri; Atsuko Yabashi; Hye-Won Shin; Yohei Katoh; Kazuhisa Nakayama
JOURNAL OF CELL SCIENCE, Sep. 2012, Peer-reviewed

Structural Basis for Membrane Binding Specificity of the Bin/Amphiphysin/Rvs (BAR) Domain of Arfaptin-2 Determined by Arl1 GTPase
Kensuke Nakamura; Zhiqiu Man; Yong Xie; Ayako Hanai; Hisayoshi Makyio; Masato Kawasaki; Ryuichi Kato; Hye-Won Shin; Kazuhisa Nakayama; Soichi Wakatsuki
JOURNAL OF BIOLOGICAL CHEMISTRY, Jul. 2012, Peer-reviewed

Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis
Hisayoshi Makyio; Minako Ohgi; Tomomi Takei; Senye Takahashi; Hiroyuki Takatsu; Yohei Katoh; Ayako Hanai; Tomoko Ueda; Yasunori Kanaho; Yong Xie; Hye-Won Shin; Hironari Kamikubo; Mikio Kataoka; Masato Kawasaki; Ryuichi Kato; Soichi Wakatsuki; Kazuhisa Nakayama
EMBO JOURNAL, May 2012, Peer-reviewed

Mechanisms of membrane curvature generation in membrane traffic
Hye-Won Shin; Hiroyuki Takatsu; Kazuhisa Nakayama
Membranes, 2012, Peer-reviewed, Invited, Lead author, Corresponding author

ARF1 and ARF3 Are Required for the Integrity of Recycling Endosomes and the Recycling Pathway
Yumika Kondo; Ayako Hanai; Waka Nakai; Yohei Katoh; Kazuhisa Nakayama; Hye-Won Shin
CELL STRUCTURE AND FUNCTION, 2012, Peer-reviewed, Corresponding author

ATP9B, a P4-ATPase (a Putative Aminophospholipid Translocase), Localizes to the trans-Golgi Network in a CDC50 Protein-independent Manner
Hiroyuki Takatsu; Keiko Baba; Takahiro Shima; Hiroyuki Umino; Utako Kato; Masato Umeda; Kazuhisa Nakayama; Hye-Won Shin
JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2011, Peer-reviewed, Corresponding author

Distinct roles of Rab11 and Arf6 in the regulation of Rab11-FIP3/arfophilin-1 localization in mitotic cells
Senye Takahashi; Tomomi Takei; Hiroshi Koga; Hiroyuki Takatsu; Hye-Won Shin; Kazuhisa Nakayama
GENES TO CELLS, Sep. 2011, Peer-reviewed

Arfaptins Are Localized to the trans-Golgi by Interaction with Arl1, but Not Arfs
Zhiqiu Man; Yumika Kondo; Hiroshi Koga; Hiroyuki Umino; Kazuhisa Nakayama; Hye-Won Shin
JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 2011, Peer-reviewed

GBF1-Arf-COPI-ArfGAP-mediated Golgi-to-ER Transport Involved in Regulation of Lipid Homeostasis
Kouhei Takashima; Akina Saitoh; Shohei Hirose; Waka Nakai; Yumika Kondo; Yasuaki Takasu; Hideaki Kakeya; Hye-Won Shin; Kazuhisa Nakayama
CELL STRUCTURE AND FUNCTION, 2011, Peer-reviewed

Functional Cross-Talk between Rab14 and Rab4 through a Dual Effector, RUFY1/Rabip4
Hideaki Yamamoto; Hiroshi Koga; Yohei Katoh; Senye Takahashi; Kazuhisa Nakayama; Hye-Won Shin
MOLECULAR BIOLOGY OF THE CELL, Aug. 2010, Peer-reviewed, Corresponding author

Three Homologous ArfGAPs Participate in Coat Protein I-mediated Transport
Akina Saitoh; Hye-Won Shin; Akane Yamada; Satoshi Waguri; Kazuhisa Nakayama
JOURNAL OF BIOLOGICAL CHEMISTRY, May 2009, Peer-reviewed, Lead author

Differential Effects of Depletion of ARL1 and ARFRP1 on Membrane Trafficking between the trans-Golgi Network and Endosomes
Kirika Nishimoto-Morita; Hye-Won Shin; Hiroko Mitsuhashi; Masashi Kitamura; Qian Zhang; Ludger Johannes; Kazuhisa Nakayama
JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 2009, Peer-reviewed, Lead author

Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation
Yuya Azuma; Mie Takada; Hye-Won Shin; Noriyuki Kioka; Kazuhisa Nakayama; Kazumitsu Ueda
GENES TO CELLS, Feb. 2009, Peer-reviewed

Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes
Ray Ishizaki; Hye-Won Shin; Hiroko Mitsuhashi; Kazuhisa Nakayama
MOLECULAR BIOLOGY OF THE CELL, Jun. 2008, Peer-reviewed, Lead author

Recruitment of Tom1L1/Srcasm to Endosomes and the Midbody by Tsg101
Yuko Yanagida-Ishizaki; Tomomi Takei; Ray Ishizaki; Hitoshi Imakagura; Senye Takahashi; Hye-Won Shin; Yohei Katoh; Kazuhisa Nakayama
CELL STRUCTURE AND FUNCTION, 2008, Peer-reviewed

Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1
Tomoo Shiba; Hiroshi Koga; Hye-Won Shin; Masato Kawasaki; Ryuichi Kato; Kazuhisa Nakayama; Soichi Wakatsuki
Proceedings of the National Academy of Sciences of the United States of America, 17 Oct. 2006, Peer-reviewed

AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors
Ray Ishizaki; Hye-Won Shin; Sanae M. M. Iguchi-Ariga; Hiroyoshi Ariga; Kazuhisa Nakayama
GENES TO CELLS, Aug. 2006, Peer-reviewed

Erratum: Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells (Journal of Neurochemistry (2005) 93 (674-85))
Shigetsune Matsuya; Hiroyuki Sakagami; Akira Tohgo; Yuji Owada; Hye-Won Shin; Hiroshi Takeshima; Kazuhisa Nakayama; Shoichi Kokubun; Hisatake Kondo
Journal of Neurochemistry, Nov. 2005, Peer-reviewed

Roles of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane trafficking
HW Shin; H Kobayashi; M Kitamura; S Waguri; T Suganuma; Y Uchiyama; K Nakayama
JOURNAL OF CELL SCIENCE, Sep. 2005, Peer-reviewed, Lead author

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
HW Shin; M Hayashi; S Christoforidis; S Lacas-Gervais; S Hoepfner; MR Wenk; J Modregger; S Uttenweiler-Joseph; M Wilm; A Nystuen; WN Frankel; M Solimena; P De Camilli; M Zerial
JOURNAL OF CELL BIOLOGY, Aug. 2005, Peer-reviewed, Lead author

Role of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane traffic
Kitamura Masashi; Shin Hye-Won; Kobayashi Hiromi; Waguri Satoshi; Uchiyama Yasuo; Nakayama Kazuhisa
CELL STRUCTURE AND FUNCTION, Jun. 2005, Peer-reviewed

Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells
S Matsuya; H Sakagami; A Tohgo; Y Owada; HW Shin; H Takeshima; K Nakayama; S Kokubun; H Kondo
JOURNAL OF NEUROCHEMISTRY, May 2005, Peer-reviewed

Expression of BIG2 and analysis of its function in mammalian cells
HW Shin; C Shinotsuka; K Nakayama
GTPASES REGULATING MEMBRANE DYNAMICS, 2005, Peer-reviewed

Roles of BIG family proteins in membrane trafficking
HW Shin; R Ishizaki; K Nakayama
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2005, Peer-reviewed

Expression of BIG2 and analysis of its function in mammalian cells
HW Shin; C Shinotsuka; K Nakayama
GTPASES REGULATING MEMBRANE DYNAMICS, 2005, Peer-reviewed

BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: Its localization to recycling endosomes and implication in the endosome integrity
HW Shin; N Morinaga; M Noda; K Nakayama
MOLECULAR BIOLOGY OF THE CELL, Dec. 2004, Peer-reviewed, Lead author

Guanine nucleotide-exchange factors for Arf GTPases: Their diverse functions in membrane traffic
HW Shin; K Nakayama
JOURNAL OF BIOCHEMISTRY, Dec. 2004, Peer-reviewed, Invited, Lead author

Dual control of membrane targeting by Ptdlns(4)P and ARF
HW Shin; K Nakayama
TRENDS IN BIOCHEMICAL SCIENCES, Oct. 2004, Peer-reviewed, Invited, Lead author

GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination
Y Shiba; Y Katoh; T Shiba; K Yoshino; H Takatsu; H Kobayashi; HW Shin; S Wakatsuki; K Nakayama
JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2004, Peer-reviewed

GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination
Y Shiba; Y Katoh; T Shiba; K Yoshino; H Takatsu; H Kobayashi; HW Shin; S Wakatsuki; K Nakayama
JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2004, Peer-reviewed

Phosphoinositides regulate membrane-dependent actin assembly by latex bead phagosomes
H Defacque; E Bos; B Garvalov; C Barret; C Roy; P Mangeat; HW Shin; Rybin, V; G Griffiths
MOLECULAR BIOLOGY OF THE CELL, Apr. 2002, Peer-reviewed

gamma-adaptin interacts directly with rabaptin-5 through its ear domain
Y Shiba; H Takatsu; HW Shin; K Nakayama
JOURNAL OF BIOCHEMISTRY, Mar. 2002, Peer-reviewed

Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: Analysis using yeast three-hybrid system
H Takatsu; M Futatsumori; K Yoshino; Y Yoshida; HW Shin; K Nakayama
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jun. 2001, Peer-reviewed

Identification and characterization of novel isoforms of COPI subunits
M Futatsumori; K Kasai; H Takatsu; FW Shin; K Nakayama
JOURNAL OF BIOCHEMISTRY, Nov. 2000, Peer-reviewed

Dynamin II is involved in endocytosis but not in the formation of transport vesicles from the trans-Golgi network
K Kasai; HW Shin; C Shinotsuka; K Murakami; K Nakayama
JOURNAL OF BIOCHEMISTRY, Apr. 1999, Peer-reviewed

Intermolecular and interdomain interactions of a dynamin-related GTP-binding protein, Dnm1p/Vps1p-like protein
HW Shin; H Takatsu; H Mukai; E Munekata; K Murakami; K Nakayama
JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 1999, Peer-reviewed, Lead author

Identification and characterization of novel clathrin adaptor-related proteins
H Takatsu; M Sakurai; HW Shin; K Murakami; K Nakayama
JOURNAL OF BIOLOGICAL CHEMISTRY, Sep. 1998, Peer-reviewed

Identification and subcellular localization of a novel mammalian dynamin-related protein homologous to yeast Vps1p and Dnm1p
HW Shin; C Shinotsuka; S Torii; K Murakami; K Nakayama
JOURNAL OF BIOCHEMISTRY, Sep. 1997, Peer-reviewed, Lead author

Misc.

Regulation mechanism of phosphatidylserine-flippase at the plasma membrane
Hye-Won Shin; Hiroyuki Takatsu
Seikagaku, 2018, Invited, Lead author, Corresponding author

Membrane curvature generation by transbilayer lipid flip-flop
Hye-Won Shin
実験医学, 2018, Invited

Roles of small GTPases and BAR domain proteins in post-Golgi membrane traffic
Hye-Won Shin; Zhiqiu Man; Kazuhisa Nakayama
Seikagaku, 2012, Invited

Roles of the Arf family of small GTPases in membrane traffic
Kazuhisa Nakayama; Hye-Won Shin
タンパク質核酸酵素, Dec. 2008, Invited

ARFによるメンブレントラフィックの調節 (特集メンブレントラフィック研究の新局面--いま明かされる細胞内輸送の仕組み)
申惠媛; 中山和久
細胞工学, Nov. 2006

Regulation of membrane trafficking by ARFs
Hye-Won Shin; Kazuhisa Nakayama
細胞工学, 2006, Invited

Analyses of interaction of FlP3 and FIP4 with Rab11 and ARFs and their roles in membrane traffic
Hiroshi Koga; Hye-Won Shin; Kazuhisa Nakayama
CELL STRUCTURE AND FUNCTION, Jun. 2005

Coordinated recruitment of Rab5, EEA1, type II inositol 5-phosphatase and type I inositol 4-phosphtase to peripheral ruffles in serum stimulated astrocytes.
M Hayashi; H Shin; S Lacas-Gervais; M Wenk; J Modregger; A Nystuen; WN Frankel; M Solimena; M Zerial; P De Camilli
MOLECULAR BIOLOGY OF THE CELL, Nov. 2004

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
H Shin; M Hayashi; S Christoforidis; S Lacas-Gervais; M Wenk; M Solimena; P De Camilli; M Zerial
MOLECULAR BIOLOGY OF THE CELL, Nov. 2004

BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: Its localization to recycling endosomes and implication in the endosome integrity
K Nakayama; H Shin
MOLECULAR BIOLOGY OF THE CELL, Nov. 2004

BIG2 function on the endosomal compartment
Hye-Won Shin; Kazuhisa Nakayama
CELL STRUCTURE AND FUNCTION, May 2004

Vesicle fusion and tethering mechanism in Golgi complex
中村暢宏; 吉村信一郎; 申惠媛
実験医学, 2003, Invited

タンパク質の輸送と細胞内局在、タンパク質がわかる
中山和久; 申惠媛; 中村暢宏
わかる実験医学シリーズ, 2003

Rab5-regulated phosphoinositides synthesis and turnover and its cellular function
H Shin; S Christoforidis; M Zerial
MOLECULAR BIOLOGY OF THE CELL, Nov. 2002

gamma-Adaptin interacts directly with Rabaptin-5 through its ear domain
K Nakayama; Y Shiba; H Takatsu; HW Shin
MOLECULAR BIOLOGY OF THE CELL, Dec. 2000

Presentations

Mechanism of cellular localization of lipid flippases
Hye-Won Shin
大阪大学タンパク質研究所セミナー生体膜上の生物化学, 05 Mar. 2021, Invited

Effect of temperature, ion and nucleotide on ATP8A1 and SERCA1a reaction mechanism
安田哲; 山崎和生; 大保貴嗣; 高津宏之; 申惠媛; Stefania Danko; 川辺淳一; 鈴木裕
第93回日本生化学会大会

Mechanism of cellular localization of lipid flippases
Hye-Won Shin
第93回日本生化学会大会, Invited

Membrane curvature generation by phospholipid flippase
Hye-Won Shin
日本薬学会第140年会, Invited

Plasma membrane deformation by phospholipid flippase and cellular functions
SHIN Hye-Won
The 57th Annual Meeting of The Biophysical Society of Japan, 24 Sep. 2019, Invited

Regulation mechanism of transbilayer lipid transport by P4-ATPase
SHIN Hye-Won
The 92nd Annual Meeting of The Japanese Biochemical Society, 18 Sep. 2019, Invited

リン脂質フリッパーゼATP11Cとezrinの相互作用
井上寛己; 高津宏之; 高山真裕; 濵本明日香; 中山和久; 申惠媛
第92回日本生化学会大会, Sep. 2019

P4-ATPaseによるグルコシルセラミドの輸送と生理的意義
高津宏之; 内藤朋樹; Siddabasavegowda; Bommegowda; 有田誠; 中山和久; 申惠媛
第92回日本生化学会大会, Sep. 2019

Dynamic localization mechanism of lipid flippases and their functions in mammalian cells
SHIN Hye-Won
2019 Molecular and Cellular Biology Gordon Research Conference, 28 Jul. 2019, Invited

リン脂質フリッパーゼによる生体膜ダイナミックス
申惠媛
2019年生理学研究所研究科（分泌研究の新展開：その普遍性と多様性）, 06 Jun. 2019, Invited

膜脂質フリッパーゼの基質多様性と生理的意義
内藤朋樹; 高津宏之; 高田直人; 中山和久; 申惠媛
第19回日本タンパク質科学会年会・第71回日本細胞生物学会大会合同年次大会, Jun. 2019

リン脂質フリッパーゼATP11C(b)の極性局在と活性化型ezrinとの関係
濵本明日香; 井上寛己; 高津宏之; 中山和久; 申惠媛
第66回日本生化学会近畿支部例会, May 2019

Membrane dynamics and phospholipid flippase activity
Hye-Won Shin
Membrane Lipid Transporter Symposium 2018, 27 Sep. 2018, Invited

Plasma membrane shape changes by phospholipid flipping activity
Hye-Won Shin
The 91st Annual Meeting of the Japan Biochemical Society, 24 Sep. 2018, Invited

ピコ秒時間けい光分光法による人工脂質二重膜と細胞膜の粘度分布の比較
林春菜; 高田直人; 高門輝; 高屋智久; 申惠媛; 岩田耕一
第12回分子科学討論会, Sep. 2018

リン脂質フリッパーゼ発現による細胞膜の粘度への影響
林春菜; 高田直人; 高門輝; 高屋智久; 申惠媛; 岩田耕一
第56回日本生物物理学会, Sep. 2018

リン脂質フリッパーゼATP8A1の反応と安定性に対する界面活性剤および脂質の影響
安田哲; 山崎和生; 大保貴嗣; 高津宏之; 申惠媛; Stefania Danko; 鈴木裕
第91回日本生化学会大会, Sep. 2018

P4-ATPaseの細胞内局在におけるATPase反応サイクルの関与
刀根卓也; 高津宏之; 中山和久; 申惠媛
第91回日本生化学会大会, Sep. 2018

リン脂質フリッパーゼATP11Cとezrinの相互作用
井上寛己; 高津宏之; 高山真裕; 中山和久; 申惠媛
第91回日本生化学会大会, Sep. 2018

脂質フリッパーゼP4-ATPaseの細胞内局在におけるN末およびC末領域の機能
岡本小百合; 内藤朋樹; 中山和久; 高津宏之; 申惠媛
第91回日本生化学会大会, Sep. 2018

リン脂質フリッパーゼATP11CのC末バリアントの特性
高津宏之; 高山真裕; 井上寛己; 中山和久; 申惠媛
第91回日本生化学会大会, Sep. 2018

Regulation mechanism of the phosphatidylserine flippase ATP11C
SHIN Hye-Won
Joint Annual Meeting of JSDB 51st and JSCB 70th, 05 Jun. 2018

N- or C-terminal cytoplasmic regions of class 5 and class 6 P4-ATPases are responsible for their subcellular localization
Okamoto, S; Naito, T; Nakayama, K; Takatsu, H; Shin, H.-W
Joint Annual Meeting of JSDB 51st and JSCB 70th, Jun. 2018

Polarized localization of the phospholipid flippase ATP11C isoform at the plasma membrane
Takayama, M; Inoue, H; Nakayama, K; Takatsu, H; Shin, H.-W
第70回日本細胞生物学会・第51回日本発生生物学会合同大会, Jun. 2018

ピコ秒時間けい光分光法を用いた細胞膜の粘度評価
林春菜; 高田直人; 高門輝; 高屋智久; 申惠媛; 岩田耕一
第43回日本分光学会, Jun. 2018

細胞膜脂質フリッパーゼの基質特異性と活性調節メカニズム
申惠媛
大阪大学蛋白質研究所セミナー生体膜上の生物化学2018, 01 Mar. 2018, Invited

P4-ATPaseのPKCによる制御機構
申惠媛
日本生体エネルギー研究会第42回討論会, 20 Dec. 2017

フリッパーゼの生化学的反応機構の解析
安田哲; 山崎和生; 大保貴嗣; 高津宏之; 申惠媛; Stefania Danko; 鈴木裕
ConBio2017, Dec. 2017

リン脂質フリッパーゼATP11Cのスプライシングバリアント間の機能的相違
高山真裕; 高津宏之; 中山和久; 申惠媛
ConBio2017, Dec. 2017

非アポトーシス細胞におけるリン脂質フリッパーゼATP11Cの制御機構
高津宏之; 高山真裕; 中山和久; 申惠媛
ConBio2017, Dec. 2017

脂質フリッパーゼの新奇基質としてグルコシルセラミドの発見とその輸送メカニズム
内藤朋樹; Bartholomew; P. Roland; Todd R. Graham; 申惠媛
ConBio2017, Dec. 2017

リン脂質フリップ活性が誘導する膜変形
高田直人; 内藤朋樹; 井上尊生; 中山和久; 申惠媛
ConBio2017, Dec. 2017

Specific substrates for P4-ATPases and their regulation in mammalian cells.
SHIN Hye-Won
The 15th International Conference on Na, K-ATPase and Related Transport ATPases, 24 Sep. 2017, Invited

一定の深さにおける細胞膜粘度評価法の開発
林春菜; Manjusha Josh; 高田直人; 高屋智久; 中村浩之; 申惠媛; 岩田耕一
第11回分子化学討論会, Sep. 2017

Identification of mammalian glucosylceramide flippase and analysis of its transport mechanism
Tomoki Naito; Bart Roland; Todd Graham; Hye-Won Shin
The 15th International Conference on Na, K-ATPase and Related Transport ATPases, Sep. 2017

Phorbol ester処理によるリン脂質フリッパーゼATP11Cの局在変化
高山真裕; 高津宏之; 中山和久; 申惠媛
生体運動合同班会議2017, Jan. 2017

P4-ATPaseのリン脂質flippase活性と細胞機能の調節
申惠媛
日本生体エネルギー研究会第41回討論会, 22 Dec. 2016

Regulation mechanism of P4-ATPase by membrane traffic
Hye-Won Shin
The 89th Annual Meeting of the Japanese Biochemical Society, 27 Sep. 2016, Invited

リン脂質フリッパーゼATP11CのPKCによる制御機構.
高津宏之; 高山真裕; 中山和久; 申惠媛
第89回日本生化学会大会, Sep. 2016

P4-ATPaseによるリン脂質フリップが膜変形に与える影響.
高田直人; 中山和久; 申惠媛
第89回日本生化学会大会., Sep. 2016

細胞内リサイクリング経路におけるリン脂質フリッパーゼの機能解析.
田中祥城; 小野夏生; 中山和久; 申惠媛
生体運動合同班会議2016, Jan. 2016

細胞膜ホスファチジルコリンのフリップ・フロップと胆汁うっ滞症の関係
田中雅久; 高津宏之; 中山和久; 申惠媛
生体運動合同班会議2016, Jan. 2016

COPI被服小胞を介するSCAP-SREBP複合体のゴルジ体から小胞体への逆行輸送による脂質代謝の調節
船橋輝記; 高島昭平; 齋藤明奈; 廣瀬祥平; 申惠媛; 中山和久
第88回日本生化学会大会・第38回日本分子生物学会年会合同大会, 01 Dec. 2015

ホスファチジルセリン取り込み異常のCHO-K1変異株（UPS-1）におけるflippaseの発現解析
高田直人; 高津宏之; 宮野吏永; 中山和久; 申惠媛
第88回日本生化学会大会・第38回日本分子生物学会年会合同大会, 01 Dec. 2015

Phospholipid flippase activities and substrate specificities of P4-ATPases and their roles in cellular function
Hye-Won Shin
The 53rd Annual meeting of The Biophysical Society of Japan, 15 Sep. 2015, Invited

リン脂質フリッパーゼATP10AのPCフリップ活性及び細胞膜ダイナミクスへの関与
内藤朋樹; 高津宏之; 宮野吏永; 高田直人; 中山和久; 申惠媛
第14回次世代を担う若手ファーマ・バイオフォーラム2015, 12 Sep. 2015

Subcellular localization and phospholipid flippase activity of class 5 P4-ATPases.
Naito, T; Takatsu, H; Nakayama, K; Shin, H.-W
18th iCeMS International Symposium & 15th International Membrane Research Forum, Mar. 2015

リン脂質フリッパーゼATP10Aのフリップ活性及び細胞膜ダイナミクスへの関与
内藤朋樹; 高津宏之; 宮野吏永; 高田直人; 中山和久; 申惠媛
第62回日本生化学会近畿支部例会, 2015

ATP8B1 (familial intrahepatic cholestasis 1) translocates phosphatidylcholine at the plasma membrane.
Takatsu, H; Tanaka, G; Nakayama, K; Shin, H.-W
18th iCeMS International Symposium & 15th International Membrane Research Forum, 2015

P4-ATPaseによるリン脂質の量的・質的変容と膜変形を伴う細胞機能の関係.
申惠媛
第87回日本生化学会大会, Oct. 2014, Invited

P4-ATPaseによる細胞ｰ細胞外マトリックス間接着の調節機構の解明
宮野吏永; 高津宏之; 中山和久; 申惠媛
第13回次世代を担う若手ファーマ・バイオフォーラム2014, 2014

ATP8B1とABCB4の協調的なリン脂質のフリップ・フロップと新構成家族性肝内胆汁うっ滞症の関係
田中雅久; 高津宏之; 中山和久; 申惠媛
第87回日本生化学会大会, 2014

クラス5 P4-ATPaseの細胞内局在およびリン脂質フリップ活性
内藤朋樹; 高津宏之; 中山和久; 申惠媛
第87回日本生化学会大会, 2014

COPI被服小胞を介するSREBP-SCAP複合体のゴルジ体から小胞体への逆行輸送
船橋輝記; 高島昭平; 齋藤明奈; 廣瀬祥平; 申惠媛; 中山和久
第87回日本生化学会大会, 2014

ホスファチジルコリンのフリップーフロップの相関性の破綻とPFIC(新構成家族性肝内胆汁うっ滞症)
高津宏之; 田中雅久; 中山和久; 申惠媛
第87回日本生化学会大会シンポジウム, 2014, Invited

リサイクリングエンドソームを介する輸送経路におけるタンパク質とリン脂質の協調的作用.
申惠媛
第86回日本生化学会大会, Sep. 2013, Invited

Membrane remodeling in post-Golgi trafficking
Hye-Won Shin
The 65th Annual Meeting of the Japan Society for Cell Biology, Jun. 2013, Invited

ATP8B1 (FIC1, familial intrahepatic cholestasis 1)はホスファチジルコリンのフリッパーゼである
高津宏之; 中山和久; 申惠媛
第86回日本生化学会大会, Mar. 2013

P4-ATPaseの細胞内小胞輸送における機能解析
小野夏生; 高津宏之; 中山和久; 申惠媛
第12回次世代を担う若手ファーマ・バイオフォーラム2013, 2013

Interplay of lipids and proteins in intracellular membrane traffic
SHIN Hye-won
第2回発生細胞生物学ミニワークショップ, Nov. 2012, Invited

生体膜の非対称性を制御するP4-ATPaseの小胞輸送における機能
Hye-Won Shin
第34回生体膜の薬物の相互作用シンポジウム, Nov. 2012

ゴルジ体ー小胞体間のタンパク質輸送による脂肪滴形成の調節
高島昭平; 齋藤明奈; 廣瀬祥平; 申惠媛; 中山和久
第85回日本生化学会大会, 2012

生体膜の脂質非対称性を調節するP4-ATPaseのゴルジ体以降の小胞輸送経路における機能解析
海野寛之; 高津宏之; 中山和久; 申惠媛
第85回日本生化学会大会, 2012

Revisiting roles of the Golgi-localizing small GTPase ARFs
Hye-Won Shin
The 84th Annual Meeting of Japanese Biochemical Society, Sep. 2011, 日本生化学会, Invited

Functional analysis of the small GTPase Arf6 during Cytokinesis
正親美菜子; 武井朋美; 高橋千絵; 申惠媛; 中山和久
第63回日本細胞生物学会大会, 2011

Arfaptins localize to the trans-Golgi in an Arl1-dependent manner and deform Golgi membranes
満智秋; 申惠媛; 中山和久
第63回日本細胞生物学会大会, 2011

Regulation of lipid droplet formation by Golgi-to-ER membrane traffic
高島皓平; 齋藤明奈; 申惠媛; 中山和久
第63回日本細胞生物学会大会, 2011

Functional analysis of class I and classII ARF small GTPases in membrane traffic
中井和香; 近藤由美香; 齋藤明奈; 中山和久; 申惠媛
第63回日本細胞生物学会大会, 2011

ゴルジ体‐小胞体間のタンパク質輸送による脂肪滴形成の調節
高島昭平; 齋藤明奈; 廣瀬祥平; 申惠媛; 中山和久
第84回日本生化学会大会, 2011

脂質二重層の非対称性を調節するP4-ATPaseのメンブレントラフィックにおける役割
島孝弘; 馬場啓子; 高津宏之; 海野寛之; 中山和久; 申惠媛
第84回日本生化学会大会, 2011

メンブレントラフィックにおけるP4-ATPase、ATP9Bの機能解析
高津宏之; 馬場啓子; 海野寛之; 島孝弘; 中山和久; 申惠媛
第84回日本生化学会大会, 2011

細胞分裂時のトランスフェリン受容体と鉄輸送体DMT1の局在変化
高津宏之; 加藤洋平; 上田智子; 高橋千絵; 申惠媛; 中山和久
フォーラム：衛生薬学・環境トキシコロジー, 2011

細胞質分裂時のRab11-FIP3/Arfophilin-1の局在調節におけるRab11とArf6の異なる役割
高橋千絵; 武井朋美; 古賀裕士; 高津宏之; 申惠媛; 中山和久
第22回生体膜と薬物の相互作用シンポジウム, 2011

Functional crosstalk between Rab14 and Rab4 through a dual effector, RUFY1/Rabip4
Yamamoto, H; Koga, H; Katoh, Y; Takahashi, S; Nakayama, K; Shin, H.-W
50th Annual Meeting of the American Society for Cell Biology, Dec. 2010

細胞内小胞輸送におけるARF4とARF5の機能解析
中井和香; 齋藤明奈; 近藤由美香; 中山和久; 申惠媛
第33回日本分子生物学会年会・第83回日本生化学会大会合同大会, Dec. 2010

ゴルジ体-小胞体間のタンパク質輸送による脂肪滴形成の調節
高島皓平; 齋藤明菜; 申惠媛; 中山和久
第33回日本分子生物学会年会・第83回日本生化学会大会合同大会, Dec. 2010

Mitosis-Coupled Sequestration of Recycling Endosomes around Spindle Pole Centrosomes
Nakayama, K; Takatsu, H; Ueda, T; Waguri, S; Takahashi, S; Kondo, Y; Shin, H.-W
第33回日本分子生物学会年会・第83回日本生化学会大会合同大会, Dec. 2010, Invited

Rab11とExocyst複合体による膜リサイクリングの調節
高橋千絵; 申惠媛; 中山和久
第32回生体膜と薬物の相互作用シンポジウム, Nov. 2010

生体膜リン脂質非対称性を司るフリッパーゼの細胞内局在
馬場啓子; 申惠媛; 中山和久
ファーマ・バイオフォーラム2010, Oct. 2010

エンドソームを介する小胞輸送経路におけるArf1とArf3の機能解析
近藤由美香; 申惠媛; 中山和久
ファーマ・バイオフォーラム2010, Oct. 2010

Roles of Small GTPase ARF1 and ARF3 in recycling endosomes
Hye-Won Shin
FASEB Summer Research Conference, “Arf Family G Proteins”, Aug. 2010

低分子量GTPaseであるARF1とARF3はり策リング経路で機能する
近藤由美香; 申惠媛; 中山和久
第62回日本細胞生物学会大会, May 2010

細胞質分裂における低分子量GTPase ARF6の機能の解析
正親美菜子; 武井朋美; 高橋千絵; 申惠媛; 中山和久
第62回日本細胞生物学会大会, May 2010

細胞質分裂におけるArf6およびEFA6 (Arf6-GEF) の局在と機能
上田智子; 近藤由美香; 申惠媛; 中山和久
第62回日本細胞生物学会大会, May 2010

ArfaptinのArl1依存的なトラスゴルジへの局在とArfaptinによるゴルジ体チューブル構造の形成
満智秋; 近藤由美香; 申惠媛; 中山和久
第62回日本細胞生物学会大会, May 2010

CRESCent: Cluster of Recycling Endosomes Transiently Formed around Spindle Pole Centrosome
Takatsu, H; Ueda, T; Waguri, S; Takahashi, S; Kondo, Y; Shin, H.-W; Nakayama, K
49th Annual Meeting of the American Society for Cell Biology, Dec. 2009

Arfのグアニンヌクレオチド交換因子BIG1とBIG2のトラスゴルジ網局在化機構の解析
高島皓平; 申惠媛; 中山和久
ファーマ・バイオフォーラム2009, Nov. 2009

メンブレントラフィックにおけるArfaptinの機能解析
満智秋; 申惠媛; 中山和久
ファーマ・バイオフォーラム2009, Nov. 2009

細胞質分裂時のArf6およびEFA6 (Arf6-GEF) の局在変化
上田智子; 武井朋美; 申惠媛; 坂上洋行; 中山和久
ファーマ・バイオフォーラム2009, Nov. 2009

RabファミリーとArfファミリーの低分子量GTPaseによる細胞質分裂の調節
中山和久; 高橋千絵; 武井朋美; 上田智子; 高津宏之; 申惠媛
第82回日本生化学会大会, Oct. 2009, Invited

分裂期間および細胞分裂時のFIP3/FIP4の局在化におけるRab11およびArf6の役割
高橋千絵; 武井朋美; 古賀裕士; 申惠媛; 中山和久
第82回日本生化学会大会, Oct. 2009

細胞質分裂時のArf6およびEFA6 (Arf6-GEF) の局在変化
上田智子; 武井朋美; 申惠媛; 坂上洋行; 中山和久
第82回日本生化学会大会, Oct. 2009

細胞質分裂における低分子量GTPase ARF6の機能の解析
武井朋美; 高橋千絵; 申惠媛; 中山和久
第61回日本細胞生物学会大会, Jun. 2009

細胞分裂におけるリサイクリングエンドソームの動態
高津宏之; 上田智子; 近藤由美香; 申惠媛; 中山和久
第61回日本細胞生物学会大会, Jun. 2009

ARFGAP1, 2, 3はCOPI被覆小胞を介する輸送経路で働く
齋藤明奈; 申惠媛; 山田茜; 和栗聡; 中山和久
第61回日本細胞生物学会大会, Jun. 2009

メンブレントラフィックにおけるArfaptin/PORの機能研究
満智秋; 申惠媛; 中山和久
第61回日本細胞生物学会大会, Jun. 2009

リソソーム分解経路における低分子量GTPase ARF3の機能
申惠媛; 近藤由美香; 中山和久
第61回日本細胞生物学会大会, Jun. 2009

低分子量GTPaseによるリサイクリングエンドソーム機能と細胞質分裂の調節
中山和久; 高橋千絵; 武井朋美; 高津宏之; 申惠媛
第31回日本分子生物学会年会・第81回日本生化学会大会合同大会, Dec. 2008, Invited

Arfのグアニンヌクレオチド交換因子BIG1とBIG2のトランスゴルジ網への局在機構の解析
高島皓平; 申惠媛; 中山和久
第31回日本分子生物学会年会・第81回日本生化学会大会合同大会, Dec. 2008

細胞内小胞輸送における低分子量GTPase Rab14の役割
山本昆明; 申惠媛; 中山和久
第31回日本分子生物学会年会・第81回日本生化学会大会合同大会, Dec. 2008

細胞内小胞輸送における新規ARF-GAPの機能解析
齋藤明奈; 申惠媛; 中山和久
ファーマ・バイオフォーラム2008, Nov. 2008

細胞質分裂における低分子量GTPase Arf6の機能の解析
武井朋美; 高橋千絵; 申惠媛; 中山和久
ファーマ・バイオフォーラム2008, Nov. 2008

ARL1 and ARFRP1 independently regulate membrane trafficking ‘to’ and ‘from’ the TGN
Shin, H.-W; Nishimoto, K; Nakayama, K
The 2008 Golgi meeting, Sep. 2008

細胞内小胞輸送におけるArfGAP1,2,3の役割
齋藤明奈; 申惠媛; 中山和久
第60回日本細胞生物学会大会, Jun. 2008

メンブレントラフィックにおけるArfaptin/POR の機能研究
満智秋; 申恵媛; 中山和久
第60 回日本細胞生物学会大会, Jun. 2008

ARFRP1とARL1によるTGN 以降の膜輸送の調節
申惠媛; 西本樹理加; 中山和久
第60 回日本細胞生物学会大会, Jun. 2008

エンドサイトーシスにおける低分子量GTPase ARF1/3 の役割
申惠媛; 石崎玲; 中山和久
第30回日本分子生物学会年会・第80回日本生化学会大会合同大会, Dec. 2007

ポストゴルジ輸送におけるArl1 の役割
西本樹理加; 申惠媛; 中山和久
第30回日本分子生物学会年会・第80回日本生化学会大会合同大会, Dec. 2007

ARF のグアニンヌクレオチド交換因子BIG1 とBIG2 の発現抑制による機能解析
石崎玲; 申惠媛; 中山和久
第30回日本分子生物学会年会・第80回日本生化学会大会合同大会, Dec. 2007

細胞内小胞輸送における低分子量GTPase Rab14 の役割
山本昆明; 申惠媛; 中山和久
第30回日本分子生物学会年会・第80回日本生化学会大会合同大会, Dec. 2007

ARFRP1 and ARL1 independently regulate membrane trafficking ‘from’ and ‘to’ the TGN
Nakayama, K; Nishimoto, K; Man, Z; Shin, H.-W
International Symposium on Membrane Traffic, Nov. 2007

Functional analysis of novel ARF-GAPs in membrane traffic. International Symposium on Membrane Traffic
Saitoh, A; Shin, H.-W; Nakayama, K
International Symposium on Membrane Traffic, Nov. 2007

Redundant roles of BIG2 and BIG1 in membrane traffic between the TGN and endosomes
Ishizaki, R; Shin, H.-W; Nakayama, K
International Symposium on Membrane Traffic, Nov. 2007

Distinct and redundant functions of BIG1 and BIG2 in TGN and recycling endosome.
SHIN Hye-won
FASEB Summer Research/CNRS Conference, Jun. 2007, Invited

Rab11とARFのエフェクター，Rab11-FIP/Arfophilinのメンブレントラフィックにおける機能
古賀裕士; 申惠媛; 張茜; 中山和久
第40回日本発生生物学会・第59回日本細胞生物学会合同大会, May 2007

Distinct and redundant functions of BIG1 and BIG2 in the TGN and recycling endosomes
Ishizaki, R; Shin, H.-W; Nakayama, K
第10回細胞膜研究フォーラム, Feb. 2007

Dual Interaction of Arfophilins/Rab11-FIPs with ARFs and Rab11
Koga, H; Shin, H.-W; Nakayama, K
46th Annual Meeting of the American Society for Cell Biology, Dec. 2006

低分子量GTPase ARFRP1の機能解析
北村雅史; 申惠媛; 中山和久
日本分子生物学会2006フォーラム, Dec. 2006

細胞内小胞輸送におけるArfGAP1～ArfGAP3の機能解析
齋藤明奈; 申惠媛; 中山和久
日本分子生物学会2006フォーラム, Dec. 2006

FIP3、FIP4によるRab11とARFの機能のクロストーク
申惠媛
日本分子生物学会2006フォーラム, Dec. 2006, Invited

Rab5-regulated phosphoinositide turnover in the endocytic pathway.
SHIN Hye-won
18th Annual Meeting of the Korean Society for Molecular and Cellular Biology, Oct. 2006, Invited

Dual Interaction of Arfophilins/Rab11-FIPs with ADP-ribosylation factor and Rab11
Koga, H; Shin, H.-W; Nakayama, K
20th IUBMB International Congress of Biochemistry and Molecular Biology, Jun. 2006

Regulation of membrane trafficking between the TGN and endosomes by ARF-GEFs
Nakayama, K; Shin, H.-W; Ishizaki, R
20th IUBMB International Congress of Biochemistry and Molecular Biology, Jun. 2006

AMY-1 is localized on the trans-Golgi network in association with brefeldin A-inhibited guanine nucleotide-exchange factor 2 (BIG2)
Ishizaki, R; Shin, H.-W; Iguchi-Ariga, S.M.M; Ariga, H; Nakayama, K
第９回国際細胞膜研究フォーラム, Mar. 2006

Dual interaction of Arfophilins/Rab11-FIPs with ADP-ribosylation factor and Rab11
Koga, H; Shin, H.-W; Nakayama, K
第９回国際細胞膜研究フォーラム, Mar. 2006

Roles of ARFRP1 (ADP-Ribosylation Factor-Related Protein 1) in Post-Golgi Membrane Trafficking
Shin, H.-W; Kobayashi, H; Kitamura, M; Nakayama, K
45th Annual Meeting of the American Society for Cell Biology, Dec. 2005

細胞内膜輸送におけるBIGファミリータンパク質の機能
申惠媛; 石崎玲; 中山和久
第27回生体膜と薬物の相互作用シンポジウム, Nov. 2005

BIG2, a Guanine Nucleotide Exchange Factor for ADP-Ribosylation Factors: Its Function at the Recycling Endosome
Shin, H.-W; Ishizaki, R; Nakayama, K
第78回日本生化学会大会, Oct. 2005

A New Method for Study of Post-Golgi Trafficking
Zhang, Q; Shin, H.-W; Nakayama, K
第78回日本生化学会大会, Oct. 2005

AMY-1 is localized on the trans-Golgi network in association with brefeldin A-inhibited guanine nucleotide-exchange factor 2 (BIG2)
Ishizaki, R; Shin, H.-W; Iguchi-Ariga, S.M.M; Ariga, H; Nakayama, K
第78回日本生化学会大会, Oct. 2005

BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: Its Function at the recycling endosome.
申惠媛
第78回日本生化学会大会, Oct. 2005, Invited

Role of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane traffic
Kitamura, M; Shin, H.-W; Kobayashi, H; Waguri, S; Uchiyama, Y; Nakayama, K
第58回日本細胞生物学会大会, Jun. 2005

Analyses of interaction of FIP3 and FIP4 with Rab11 and ARFs and their roles in membrane traffic
Koga, H; Shin, H.-W; Nakayama, K
第58回日本細胞生物学会大会, Jun. 2005

BIG2, a Guanine Nucleotide Exchange Factor for ADP-Ribosylation Factors: Its Localization to Recycling Endosomes and Implication in the Endosome Integrity
Nakayama, K; Shin, H.-W
44th Annual Meeting of the American Society for Cell Biology, Dec. 2004

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
Shin, H.-W; Hayashi, M; Christoforidis; S; Lacas-Gervais, S; Wenk, M; Solimena, M; De Camilli, P; Zerial, M
44th Annual Meeting of the American Society for Cell Biology, Dec. 2004

The subcellular localization and the role of ARF-related protein (ARF-RP)
Shin, H.-W; Kobayashi, H; Nakayama, K
第57回日本細胞生物学会大会, May 2004

BIG2 function on the endosomal compartment.
Shin, H.-W; Kobayashi, H; Nakayama, K
第57回日本細胞生物学会大会, May 2004

Rab5-regulated phosphoinositides synthesis and turnover and its cellular function
Shin, H.-W; Christoforidis, S; Zerial, M
42nd Annual Meeting of the American Society for Cell Biology, Dec. 2002

gamma-Adaptin interacts directly with Rabaptin-5 through its ear domain
Nakayama, K; Shiba, Y; Takatsu, H; Shin, H.-W
40th Annual meeting of American Society for Cell Biology, Dec. 2000

gamma-アダプチンとRabaptin5の相互作用の解析
芝陽子; 高津宏之; 申惠媛; 中山和久
第73回日本生化学会大会, Oct. 2000

アダプター蛋白質複合体とCOP I複合体の形成は同様のサブユニット間相互作用により支配される
吉野佳織; 高津宏之; 二ツ森睦美; 吉田雄作; 申惠媛; 中山和久
第73回日本生化学会大会, Oct. 2000

Self-association of Dnm1p/Vps1p-like protein (DVLP), a novel member of the dynamin GTPase family
Shin, H.-W
3rd Congress of the Asian-Pacific Organization for Cell Biology, Aug. 1998

新奇ダイナミン様GTP結合蛋白質の同定と細胞内局在
申惠媛
第50回日本細胞生物学会大会, Sep. 1997

Regulation of activity and localization of phosphatidylserine flippase, ATP11C
Hiroyuki Takatsu; Hiroki Inoue; Masahiro Takayama; Hye-Won Shin
Cell Bio virtual 2021

Mechanism of polarized localization of phospholipid flippase ATP11C
Hiroki Inoue; Hiroyuki Takatsu; Hye-Won Shin
第94回日本生化学会大会

ゴーシェ病患者の細胞にみられるリソソームの機能異常
喜多夏暉; 濵本明日香; 高津宏之; 中山和久; 申惠媛
第42回生体膜と薬物の相互作用シンポジウム

Books and Other Publications

レーニンジャ―新生化学：生化学と分子生物学の基本原理（第7版）
申惠媛, Joint translation, 第11章
廣川書店, 2019, Not refereed

Dojin BioScience Series 24 メンブレントラフィック
申惠媛; 中山和久, Joint work, Arfファミリーによるメンブレントラフィックの調節
化学同人, 2016, Not refereed

レーニンジャ―新生化学：生化学と分子生物学の基本原理（第6版）
申惠媛, Joint translation, 第11章
廣川書店, 2015, Not refereed

プロッパー細胞生物学：細胞の基本原理を学ぶ（第1版）
申惠媛, Joint translation, 第4章、第13章
化学同人, 2013, Not refereed

Media Coverage

Flipping lipids to deform membranes
https://www.asbmb.org/asbmb-today/science/010720/flipping-lipids-to-deform-membranes, Jan. 2020, Pr

Kyodai sensei theater
Kyoto Univ., 2019, Internet

Cells Flip Lipids To Bend Their Membranes
https://www.asianscientist.com/2018/04/in-the-lab/atp10a-lipid-flip-membrane-deformation/, Apr. 2018, Internet

リン脂質の移動によって細胞膜が変形するメカニズムを解明
https://www.kyoto-u.ac.jp/ja/research-news/2018-03-30, Mar. 2018, Internet

Flipping lipids for cell transport-tubules
https://www.eurekalert.org/pub_releases/2018-03/ku-flf032818.php;https://phys.org/news/2018-03-flipping-lipids-cell-transport-tubules.html;https://www.sciencedaily.com/releases/2018/03/180329141014.htm, Mar. 2018, Internet

京大、細胞膜の脂質輸送の仕組みの一端を解明
https://www.nikkei.com/article/DGXLRSP463650_X11C17A1000000/?au=0, Nov. 2017, Internet

細胞膜の脂質輸送、セロトニンやヒスタミンの受容体の仕組みの一端を解明
https://www.kyoto-u.ac.jp/ja/research-news/2017-11-17-0, Nov. 2017, Internet

External funds: Kakenhi

Physiological roles of lipid asymmetry in biological membranes mediated by lipid flippases
Grant-in-Aid for Scientific Research (B)
Basic Section 43030:Functional biochemistry-related
Kyoto University
申惠媛
From 01 Apr. 2020, To 31 Mar. 2023, Granted
生体膜;P4-ATPase;フリッパーゼ
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H03209/

Relationship between architecture and function of intraciliary protein trafficking complex: molecular basis for ciliopathies
Grant-in-Aid for Scientific Research (A)
Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Kyoto University
中山和久
From 01 Apr. 2019, To 31 Mar. 2024, Granted
繊毛内タンパク質輸送;繊毛病;タンパク質間相互作用;CRISPR/CAS9システム;CRISPR/Cas9システム;繊毛
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19H00980/

Regulation of enzymatic activities of P4-ATPases and its physiological function
Grant-in-Aid for Scientific Research (B)
Kyoto University
Hye-Won Shin
From 01 Apr. 2017, To 31 Mar. 2020, Project Closed
生体膜;フリッパーゼ;脂質二重層;P4-ATPase;ホスファチジルセリン;細胞極性;エンドサイトーシス;細胞・組織;脂質
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17H03655/

P4-ATPase-mediated dynamic ordering of phospholipids in biological membranes
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Science and Engineering
Kyoto University
申惠媛
From 01 Apr. 2016, To 31 Mar. 2018, Project Closed
生体膜;リン脂質;フリッパーゼ;細胞・組織;脂質;脂質二重層
https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-16H00764/

膜運動におけるリン脂質の量的・質的変化の作用機序
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Biological Sciences
Kyoto University
申惠媛
From 01 Apr. 2015, To 31 Mar. 2017, Project Closed
細胞膜;リン脂質;膜変形;生体膜;細胞・組織;脂質;脂質二重層;P4-ATPase
https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-15H01320/

Transbilayer lipid asymmetry and cholestasis
Grant-in-Aid for Scientific Research (C)
Kyoto University
Hye-Won Shin
From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
生体膜;リン脂質;非対称性;細胞;胆汁酸;P4-ATPase;PFIC;胆汁うっ滞症;膜ダイナミクス;胆汁うっ滞
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26460065/

Functional crosstalk between ARF and Rab small GTPases
Grant-in-Aid for Scientific Research (C)
Kyoto University
Hye-Won SHIN
From 28 Apr. 2011, To 31 Mar. 2014, Project Closed
メンブレントラフィック;小胞輸送;エンドソーム;生体膜;Gタンパク質;リサイクリング;低分子量GTPase;細胞;タンパク質
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23570162/

生体膜の非対称性を制御するＰ４－ＡＴＰａｓｅのメンブレントラフィックにおける役割
Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Biological Sciences
Kyoto University
申惠媛
From 01 Apr. 2011, To 31 Mar. 2013, Project Closed
メンブレントラフィック;脂質二重層;脂質非対称性;P4-ATPase;リン脂質
https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-23113714/

Regulatory mechanism of Rab14 and its effector proteins in post-Golgi membrane trafficking
Grant-in-Aid for Young Scientists (B)
Kyoto University
Hye-Won SHIN
Project Closed
細胞;メンブレントラフィック;小胞輸送;低分子量GTPase;エンドソーム;低分量GTPase;Small GTPase
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21770203/

Regulation of membrane trafficking by small GTPase ARFRP1
Grant-in-Aid for Young Scientists (B)
Kyoto University
Hye-won SHIN
Project Closed
小胞輸送;メンブレントラフィック;ゴルジ体;低分子量GTPase
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19770169/

Roles of multifunctional adaptor proteins, GGAs, in membrane traffic
Grant-in-Aid for Scientific Research (A)
Kyoto University
Kazuhisa NAKAYAMA
Project Closed
細胞・組織;生体分子;蛋白質;薬学;GGA;GATドメイン;ユビキチン;小胞輸送;X線結晶構造解析;Tom1;Tollip, Cells and tissues;Biomolecules;Proteins;Pharmaceutical sciences
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15209002/

ゴルジ体を中心とするメンブレントラフィックの制御機構
Grant-in-Aid for Scientific Research on Priority Areas
Biological Sciences
Kyoto University
中山和久
Project Closed
ARF;Rab;メンブレントラフィック;小胞輸送;細胞・組織;生体分子;蛋白質;薬学;BIG2;TGN;エンドソーム;GGA;Tom1;GATドメイン;ユビキチン;X線結晶構造解析
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15079204/

Last Updated :2022/06/24

Education

Teaching subject(s)

From 01 Apr. 2022, To 31 Mar. 2023
２１ＣＯＥ化学講義３（理）
8001, Spring, Graduate School of Pharmaceutical Sciences, 2

From 01 Apr. 2022, To 31 Mar. 2023
Pharmaceutical Laboratory IV : Biochemistry and Microbiology
C906, Fall, Faculty of Pharmaceutical Sciences, 3

From 01 Apr. 2022, To 31 Mar. 2023
Pharmaceutical Health Science I (Health Chemistry)
C212, Spring, Faculty of Pharmaceutical Sciences, 2

From 01 Apr. 2022, To 31 Mar. 2023
Bioligical Chemistry 2 (Energy Metabolism)
A202, Spring, Faculty of Pharmaceutical Sciences, 2

From 01 Apr. 2022, To 31 Mar. 2023
Pharmaceutical Health Science 1 (Health Chemistry)
A212, Spring, Faculty of Pharmaceutical Sciences, 2

From 01 Apr. 2022, To 31 Mar. 2023
Basic Laboratory Techniques in Biological Chemistry
1207, Spring, Graduate School of Pharmaceutical Sciences, 2

From 01 Apr. 2022, To 31 Mar. 2023
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
A906, Fall, Faculty of Pharmaceutical Sciences, 4

From 01 Apr. 2022, To 31 Mar. 2023
Seminar in Basic Physiological Chemistry
2306, Year-long, Graduate School of Pharmaceutical Sciences, 2

From 01 Apr. 2022, To 31 Mar. 2023
Laboratory Practice in Basic Physiological Chemistry
4206, Year-long, Graduate School of Pharmaceutical Sciences, 1

From 01 Apr. 2022, To 31 Mar. 2023
Biological Chemistry II (Energy Metabolism)
C202, Spring, Faculty of Pharmaceutical Sciences, 2

From 01 Apr. 2022, To 31 Mar. 2023
Advanced Pharmaceutical Biochemistry B
8206, Spring, Graduate School of Pharmaceutical Sciences, 1

From 01 Apr. 2022, To 31 Mar. 2023
Research in Basic Physiological Chemistry
3206, Year-long, Graduate School of Pharmaceutical Sciences, 4

From Apr. 2011, To Mar. 2012
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2011, To Mar. 2012
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2011, To Mar. 2012
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2012, To Mar. 2013
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2012, To Mar. 2013
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2012, To Mar. 2013
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2013, To Mar. 2014
Bioligical Chemistry 2 (Energy Metabolism)
Spring, 薬学部

From Apr. 2013, To Mar. 2014
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2013, To Mar. 2014
Introduction to Basic Biological Chemistry
Spring, 薬学研究科

From Apr. 2013, To Mar. 2014
Basic Laboratory Techniques in Biological Chemistry
Spring, 薬学研究科

From Apr. 2013, To Mar. 2014
Basic Laboratory Techniques in Biological Chemistry
Fall, 薬学研究科

From Apr. 2013, To Mar. 2014
Advanced Basic Biological Chemistry I
Spring, 薬学研究科

From Apr. 2013, To Mar. 2014
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2013, To Mar. 2014
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2013, To Mar. 2014
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2013, To Mar. 2014
Global Frontier in Life Science A
Spring, 生命科学研究科

From Apr. 2014, To Mar. 2015
Bioligical Chemistry 2 (Energy Metabolism)
Spring, 薬学部

From Apr. 2014, To Mar. 2015
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2014, To Mar. 2015
Introduction to Basic Biological Chemistry
Spring, 薬学研究科

From Apr. 2014, To Mar. 2015
Basic Laboratory Techniques in Biological Chemistry
Spring, 薬学研究科

From Apr. 2014, To Mar. 2015
Basic Laboratory Techniques in Biological Chemistry
Fall, 薬学研究科

From Apr. 2014, To Mar. 2015
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2014, To Mar. 2015
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2014, To Mar. 2015
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2014, To Mar. 2015
Global Frontier in Life Science A
Spring, 生命科学研究科

From Apr. 2014, To Mar. 2015
The Role of Life Science in Drug Discovery
Spring, 全学共通科目

From Apr. 2015, To Mar. 2016
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2015, To Mar. 2016
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2015, To Mar. 2016
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2015, To Mar. 2016
Basic Laboratory Techniques in Biological Chemistry
Spring, 薬学研究科

From Apr. 2015, To Mar. 2016
Basic Laboratory Techniques in Biological Chemistry
Fall, 薬学研究科

From Apr. 2015, To Mar. 2016
Introduction to Basic Biological Chemistry
Spring, 薬学研究科

From Apr. 2015, To Mar. 2016
Advanced Basic Biological Chemistry I
Spring, 薬学研究科

From Apr. 2015, To Mar. 2016
Bioligical Chemistry 2 (Energy Metabolism)
Spring, 薬学部

From Apr. 2015, To Mar. 2016
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2015, To Mar. 2016
The Role of Life Science in Drug Discovery
Spring, 全学共通科目

From Apr. 2016, To Mar. 2017
ILAS Seminar
Spring, 全学共通科目

From Apr. 2016, To Mar. 2017
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2016, To Mar. 2017
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2016, To Mar. 2017
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2016, To Mar. 2017
Basic Laboratory Techniques in Biological Chemistry
Spring, 薬学研究科

From Apr. 2016, To Mar. 2017
Basic Laboratory Techniques in Biological Chemistry
Fall, 薬学研究科

From Apr. 2016, To Mar. 2017
Introduction to Basic Biological Chemistry
Spring, 薬学研究科

From Apr. 2016, To Mar. 2017
Bioligical Chemistry 2 (Energy Metabolism)
Spring, 薬学部

From Apr. 2016, To Mar. 2017
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2017, To Mar. 2018
Introduction to Modern Life Sciences for Drug Discovery
Spring, 薬学研究科

From Apr. 2017, To Mar. 2018
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2017, To Mar. 2018
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2017, To Mar. 2018
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2017, To Mar. 2018
Basic Laboratory Techniques in Biological Chemistry
Spring, 薬学研究科

From Apr. 2017, To Mar. 2018
Basic Laboratory Techniques in Biological Chemistry
Fall, 薬学研究科

From Apr. 2017, To Mar. 2018
Bioligical Chemistry 2 (Energy Metabolism)
Spring, 薬学部

From Apr. 2017, To Mar. 2018
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2018, To Mar. 2019
Introduction to Modern Life Sciences for Drug Discovery
Spring, 薬学研究科

From Apr. 2018, To Mar. 2019
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2018, To Mar. 2019
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2018, To Mar. 2019
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2018, To Mar. 2019
Basic Laboratory Techniques in Biological Chemistry
Spring, 薬学研究科

From Apr. 2018, To Mar. 2019
Basic Laboratory Techniques in Biological Chemistry
Fall, 薬学研究科

From Apr. 2018, To Mar. 2019
Bioligical Chemistry 2 (Energy Metabolism)
Spring, 薬学部

From Apr. 2018, To Mar. 2019
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2019, To Mar. 2020
Laboratory Practice in Basic Physiological Chemistry
Spring, 薬学研究科

From Apr. 2019, To Mar. 2020
Laboratory Practice in Basic Physiological Chemistry
Fall, 薬学研究科

From Apr. 2019, To Mar. 2020
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2019, To Mar. 2020
Research in Basic Physiological Chemistry
Spring, 薬学研究科

From Apr. 2019, To Mar. 2020
Research in Basic Physiological Chemistry
Fall, 薬学研究科

From Apr. 2019, To Mar. 2020
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2019, To Mar. 2020
Seminar in Basic Physiological Chemistry
Spring, 薬学研究科

From Apr. 2019, To Mar. 2020
Seminar in Basic Physiological Chemistry
Fall, 薬学研究科

From Apr. 2019, To Mar. 2020
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2019, To Mar. 2020
Basic Laboratory Techniques in Biological Chemistry
Spring, 薬学研究科

From Apr. 2019, To Mar. 2020
Basic Laboratory Techniques in Biological Chemistry
Fall, 薬学研究科

From Apr. 2019, To Mar. 2020
Fundamental Chemical Experiments
Fall, 全学共通科目

From Apr. 2019, To Mar. 2020
Biological Chemistry II (Energy Metabolism)
Spring, 薬学部

From Apr. 2019, To Mar. 2020
Bioligical Chemistry 2 (Energy Metabolism)
Spring, 薬学部

From Apr. 2019, To Mar. 2020
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2020, To Mar. 2021
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2020, To Mar. 2021
Laboratory Practice in Basic Physiological Chemistry
Spring, 薬学研究科

From Apr. 2020, To Mar. 2021
Laboratory Practice in Basic Physiological Chemistry
Fall, 薬学研究科

From Apr. 2020, To Mar. 2021
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2020, To Mar. 2021
Research in Basic Physiological Chemistry
Spring, 薬学研究科

From Apr. 2020, To Mar. 2021
Research in Basic Physiological Chemistry
Fall, 薬学研究科

From Apr. 2020, To Mar. 2021
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2020, To Mar. 2021
Seminar in Basic Physiological Chemistry
Spring, 薬学研究科

From Apr. 2020, To Mar. 2021
Seminar in Basic Physiological Chemistry
Fall, 薬学研究科

From Apr. 2020, To Mar. 2021
Basic Laboratory Techniques in Biological Chemistry
Spring, 薬学研究科

From Apr. 2020, To Mar. 2021
Basic Laboratory Techniques in Biological Chemistry
Fall, 薬学研究科

From Apr. 2020, To Mar. 2021
Biological Chemistry II (Energy Metabolism)
Spring, 薬学部

From Apr. 2020, To Mar. 2021
Biological Chemistry 2 (Energy Metabolism)
Spring, 薬学部

From Apr. 2020, To Mar. 2021
Basic Laboratory Techniques in Pharmaceutical Sciences
Spring, 薬学研究科

From Apr. 2020, To Mar. 2021
Pharmaceutical Laboratory IV : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2020, To Mar. 2021
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2021, To Mar. 2022
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2021, To Mar. 2022
Laboratory Practice in Basic Physiological Chemistry
Spring, 薬学研究科

From Apr. 2021, To Mar. 2022
Laboratory Practice in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2021, To Mar. 2022
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2021, To Mar. 2022
Research in Basic Physiological Chemistry
Spring, 薬学研究科

From Apr. 2021, To Mar. 2022
Research in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2021, To Mar. 2022
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2021, To Mar. 2022
Seminar in Basic Physiological Chemistry
Spring, 薬学研究科

From Apr. 2021, To Mar. 2022
Seminar in Basic Physiological Chemistry
Year-long, 薬学研究科

From Apr. 2021, To Mar. 2022
Basic Laboratory Techniques in Biological Chemistry
Spring, 薬学研究科

From Apr. 2021, To Mar. 2022
Basic Laboratory Techniques in Biological Chemistry
Fall, 薬学研究科

From Apr. 2021, To Mar. 2022
Biological Chemistry II (Energy Metabolism)
Spring, 薬学部

From Apr. 2021, To Mar. 2022
Biological Chemistry 2 (Energy Metabolism)
Spring, 薬学部

From Apr. 2021, To Mar. 2022
Basic Laboratory Techniques in Pharmaceutical Sciences
Spring, 薬学研究科

From Apr. 2021, To Mar. 2022
Pharmaceutical Laboratory IV : Biochemistry and Microbiology
Fall, 薬学部

From Apr. 2021, To Mar. 2022
Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
Fall, 薬学部

Last Updated :2022/06/24

Administration

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From 01 Apr. 2022, To 31 Mar. 2023
国際高等教育院企画評価専門委員会初修外国語部会委員

From 01 Apr. 2017, To 31 Mar. 2019
環境管理専門委員会無機廃液管理小委員会委員

From 01 May 2016, To 31 Mar. 2019
国際高等教育院企画評価専門委員会初修外国語部会委員

From 01 Apr. 2017
環境安全保全機構環境管理専門委員会委員(無機)

From 01 Apr. 2019, To 31 Mar. 2020
国際高等教育院企画評価専門委員会初修外国語部会委員

From 01 Apr. 2020, To 31 Mar. 2021
国際高等教育院企画評価専門委員会初修外国語部会委員

From 01 Apr. 2021, To 31 Mar. 2022
国際高等教育院企画評価専門委員会初修外国語部会委員

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人権委員会委員

From 01 Apr. 2019, To 31 Mar. 2022
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Shin, Hye-won

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