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Shin, Hye-won

Graduate School of Pharmaceutical Sciences, Division of Pharmaceutical Sciences Associate Professor

Shin, Hye-won
list
    Last Updated :2022/05/14

    Basic Information

    Faculty

    • 薬学部

    Concurrent Affiliation

    • Graduate School of Biostudies, 生命科学研究科 Global Frontier in Life Science A
    • Graduate School of Pharmaceutical Sciences, 薬学研究科 連携助教
    • Graduate School of Pharmaceutical Sciences, 薬学研究科 基礎物理化学特論Ⅱ

    Professional Memberships

    • Korean Society for Molecular and Cellular Biology
    • American Society for Biochemistry and Molecular Biology
    • The American Society for Cell Biology
    • 日本薬学会
    • 日本生化学会
    • 日本細胞生物学会

    Academic Degree

    • Master of Science(Kyungpook National University)
    • PhD(University of Tsukuba)

    Language of Instruction

    • Japanese
    • English
    • Korean

    ID,URL

    Website(s) (URL(s))

    researchmap URL

    list
      Last Updated :2022/05/14

      Research

      Research Topics, Overview of the research

      • Research Topics

        Biological membrane dynamics in cell physiology
      • Overview of the research

        Lipid bilayers, including those of the plasma membrane and the membrane-enclosed compartments along the secretory and endocytic pathways, exhibit asymmetric lipid distributions. The asymmetric distributions are generated and regulated by flippases (P4-ATPases), floppases (ABC transporters), and scramblases. Spatio-temporal regulation of the lipid asymmetry is critical for many biological processes, such as apoptotic cell death, platelet coagulation, fusion of muscle cells, cytokinesis, cell migration, sperm capacitation and intracellular membrane trafficking. However, the molecular mechanism is largely unknown. We aim to elucidate that how spatio-temporal lipid composition changes are regulated and how such changes regulate cellular function and further homeostasis of organisms.

      Research Areas

      • Life sciences, Cell biology

      Papers

      • The interaction of ATP11C-b with ezrin contributes to its polarized localization
        Hiroki Inoue; Hiroyuki Takatsu; Asuka Hamamoto; Masahiro Takayama; Riki Nakabuchi; Yumeka Muranaka; Tsukasa Yagi; Kazuhisa Nakayama; Hye-Won Shin
        Journal of Cell Science, 16 Sep. 2021, Peer-reviewed, Corresponding author
      • The N- or C-terminal cytoplasmic regions of P4-ATPases determine their cellular localization.
        Sayuri Okamoto; Tomoki Naito; Ryo Shigetomi; Yusuke Kosugi; Kazuhisa Nakayama; Hiroyuki Takatsu; Hye-Won Shin
        Molecular biology of the cell, 01 Sep. 2020, Peer-reviewed, Corresponding author
      • Phosphatidylserine exposure in living cells
        Hye-Won Shin; Hiroyuki Takatsu
        Critical Reviews in Biochemistry and Molecular Biology, 03 Mar. 2020, Peer-reviewed, Corresponding author
      • ATPase reaction cycle of P4‐ATPases affects their transport from the endoplasmic reticulum
        Takuya Tone; Kazuhisa Nakayama; Hiroyuki Takatsu; Hye‐Won Shin
        FEBS Letters, Feb. 2020, Peer-reviewed, Corresponding author
      • The cytoplasmic C-terminal region of the ATP11C variant determines its localization at the polarized plasma membrane
        Masahiro Takayama; Hiroyuki Takatsu; Asuka Hamamoto; Hiroki Inoue; Tomoki Naito; Kazuhisa Nakayama; Hye-Won Shin
        Journal of Cell Science, 01 Sep. 2019, Peer-reviewed, Corresponding author
      • Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs
        Bartholomew P. Roland; Tomoki Naito; Jordan T. Best; Cayetana Arnaiz-Yépez; Hiroyuki Takatsu; Roger J. Yu; Hye-Won Shin; Todd R. Graham
        Journal of Biological Chemistry, 08 Feb. 2019, Peer-reviewed
      • Phospholipid-flipping activity of P4-ATPase drives membrane curvature
        Naoto Takada; Tomoki Naito; Takanari Inoue; Kazuhisa Nakayama; Hiroyuki Takatsu; Hye-Won Shin
        EMBO Journal, 02 May 2018, Peer-reviewed, Corresponding author
      • Substrates of P4-ATPases: beyond aminophospholipids (phosphatidylserine and phosphatidylethanolamine)
        Hye-Won Shin; Hiroyuki Takatsu
        FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Peer-reviewed, Corresponding author
      • Uptake of glucose-conjugated MGMT inhibitors in cancer cells: role of flippases and type IV P-type ATPases
        Karl-Heinz Tomaszowski; Nadja Hellmann; Viviane Ponath; Hiroyuki Takatsu; Hye-Won Shin; Bernd Kaina
        Scientific Reports, Dec. 2017, Peer-reviewed
      • Phospholipid flippase ATP11C is endocytosed and downregulated following Ca2+-mediated protein kinase C activation
        Hiroyuki Takatsu; Masahiro Takayama; Tomoki Naito; Naoto Takada; Kazuya Tsumagari; Yasushi Ishihama; Kazuhisa Nakayama; Hye-Won Shin
        NATURE COMMUNICATIONS, Nov. 2017, Peer-reviewed, Corresponding author
      • Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane (vol 289, pg 33543, 2014)
        Hiroyuki Takatsu; Gaku Tanaka; Katsumori Segawa; Jun Suzuki; Shigekazu Nagata; Kazuhisa Nakayama; Hye-Won Shin
        JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2016, Peer-reviewed, Corresponding author
      • The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane
        Yoshiki Tanaka; Natsuki Ono; Takahiro Shima; Gaku Tanaka; Yohei Katoh; Kazuhisa Nakayama; Hiroyuki Takatsu; Hye-Won Shin
        Molecular biology of the cell, 2016, Peer-reviewed, Corresponding author
      • Alteration of transbilayer phospholipid compositions is involved in cell adhesion, cell spreading, and focal adhesion formation
        Rie Miyano; Takashi Matsumoto; Hiroyuki Takatsu; Kazuhisa Nakayama; Hye-Won Shin
        FEBS letters, 2016, Peer-reviewed, Corresponding author
      • Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis
        Ayako Hanai; Minako Ohgi; Chikako Yagi; Tomoko Ueda; Hye-Won Shin; Kazuhisa Nakayama
        Journal of biochemistry, 2016, Peer-reviewed
      • ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner (vol 286, pg 38159, 2011)
        Hiroyuki Takatsu; Keiko Baba; Takahiro Shima; Hiroyuki Umino; Utako Kato; Masato Umeda; Kazuhisa Nakayama; Hye-Won Shin
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 2015, Peer-reviewed, Corresponding author
      • ATP11C mutation is responsible for the defect in phosphatidylserine uptake in UPS-1 cells
        Naoto Takada; Hiroyuki Takatsu; Rie Miyano, Kazuhisa Nakayama; Hye-Won Shin
        Journal of lipid research, 2015, Peer-reviewed, Corresponding author
      • Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics
        Tomoki Naito; Hiroyuki Takatsu; Rie Miyano; Naoto Takada; Kazuhisa Nakayama; Hye-Won Shin
        The Journal of biological chemistry, 2015, Peer-reviewed, Corresponding author
      • SNAP23/25 and VAMP2 mediate exocytic event of transferrin receptor-containing recycling vesicles
        Keiji Kubo; Minako Kobayashi; Shohei Nozaki; Chikako Yagi; Kiyotaka Hatsuzawa; Yohei Katoh; Hye-Won Shin; Senye Takahashi; Kazuhisa Nakayama
        Biology open, 2015, Peer-reviewed
      • COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions
        Kouhei Takashima; Akina Saitoh; Teruki Funabashi; Shohei Hirose, Chikako Yagi; Shohei Nozaki; Ryuichiro Sato; Hye-Won Shin; Kazuhisa Nakayama
        Journal of cell science, 2015, Peer-reviewed
      • Phospholipid Flippase Activities and Substrate Specificities of Human Type IV P-type ATPases Localized to the Plasma Membrane
        Hiroyuki Takatsu; Gaku Tanaka; Katsumori Segawa; Jun Suzuki; Shigekazu Nagata; Kazuhisa Nakayama; Hye-Won Shin
        JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2014, Peer-reviewed, Corresponding author
      • ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus
        Waka Nakai; Yumika Kondo; Akina Saitoh; Tomoki Naito; Kazuhisa Nakayama; Hye-Won Shin
        Molecular Biology of the Cell, 15 Aug. 2013, Peer-reviewed, Corresponding author
      • Mitosis-coupled, microtubule-dependent clustering of endosomal vesicles around centrosomes
        Hiroyuki Takatsu; Yohei Katoh; Tomoko Ueda; Satoshi Waguri; Takashi Murayama; Senye Takahashi; Hye-Won Shin; Kazuhisa Nakayama
        Cell structure and function, 2013, Peer-reviewed
      • EFA6 activates Arf6 and participates in its targeting to the Flemming body during cytokinesis
        Tomoko Ueda; Ayako Hanai; Tomomi Takei; Keiji Kubo; Minako Ohgi; Hiroyuki Sakagami; Senye Takahashi; Hye-Won Shin; Kazuhisa Nakayama
        FEBS letters, 2013, Peer-reviewed
      • Rab11 regulates exocytosis of recycling vesicles at the plasma membrane
        Senye Takahashi; Keiji Kubo; Satoshi Waguri; Atsuko Yabashi; Hye-Won Shin; Yohei Katoh; Kazuhisa Nakayama
        JOURNAL OF CELL SCIENCE, Sep. 2012, Peer-reviewed
      • Structural Basis for Membrane Binding Specificity of the Bin/Amphiphysin/Rvs (BAR) Domain of Arfaptin-2 Determined by Arl1 GTPase
        Kensuke Nakamura; Zhiqiu Man; Yong Xie; Ayako Hanai; Hisayoshi Makyio; Masato Kawasaki; Ryuichi Kato; Hye-Won Shin; Kazuhisa Nakayama; Soichi Wakatsuki
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jul. 2012, Peer-reviewed
      • Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis
        Hisayoshi Makyio; Minako Ohgi; Tomomi Takei; Senye Takahashi; Hiroyuki Takatsu; Yohei Katoh; Ayako Hanai; Tomoko Ueda; Yasunori Kanaho; Yong Xie; Hye-Won Shin; Hironari Kamikubo; Mikio Kataoka; Masato Kawasaki; Ryuichi Kato; Soichi Wakatsuki; Kazuhisa Nakayama
        EMBO JOURNAL, May 2012, Peer-reviewed
      • Mechanisms of membrane curvature generation in membrane traffic
        Hye-Won Shin; Hiroyuki Takatsu; Kazuhisa Nakayama
        Membranes, 2012, Peer-reviewed, Invited, Lead author, Corresponding author
      • ARF1 and ARF3 Are Required for the Integrity of Recycling Endosomes and the Recycling Pathway
        Yumika Kondo; Ayako Hanai; Waka Nakai; Yohei Katoh; Kazuhisa Nakayama; Hye-Won Shin
        CELL STRUCTURE AND FUNCTION, 2012, Peer-reviewed, Corresponding author
      • ATP9B, a P4-ATPase (a Putative Aminophospholipid Translocase), Localizes to the trans-Golgi Network in a CDC50 Protein-independent Manner
        Hiroyuki Takatsu; Keiko Baba; Takahiro Shima; Hiroyuki Umino; Utako Kato; Masato Umeda; Kazuhisa Nakayama; Hye-Won Shin
        JOURNAL OF BIOLOGICAL CHEMISTRY, Nov. 2011, Peer-reviewed, Corresponding author
      • Distinct roles of Rab11 and Arf6 in the regulation of Rab11-FIP3/arfophilin-1 localization in mitotic cells
        Senye Takahashi; Tomomi Takei; Hiroshi Koga; Hiroyuki Takatsu; Hye-Won Shin; Kazuhisa Nakayama
        GENES TO CELLS, Sep. 2011, Peer-reviewed
      • Arfaptins Are Localized to the trans-Golgi by Interaction with Arl1, but Not Arfs
        Zhiqiu Man; Yumika Kondo; Hiroshi Koga; Hiroyuki Umino; Kazuhisa Nakayama; Hye-Won Shin
        JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 2011, Peer-reviewed
      • GBF1-Arf-COPI-ArfGAP-mediated Golgi-to-ER Transport Involved in Regulation of Lipid Homeostasis
        Kouhei Takashima; Akina Saitoh; Shohei Hirose; Waka Nakai; Yumika Kondo; Yasuaki Takasu; Hideaki Kakeya; Hye-Won Shin; Kazuhisa Nakayama
        CELL STRUCTURE AND FUNCTION, 2011, Peer-reviewed
      • Functional Cross-Talk between Rab14 and Rab4 through a Dual Effector, RUFY1/Rabip4
        Hideaki Yamamoto; Hiroshi Koga; Yohei Katoh; Senye Takahashi; Kazuhisa Nakayama; Hye-Won Shin
        MOLECULAR BIOLOGY OF THE CELL, Aug. 2010, Peer-reviewed, Corresponding author
      • Three Homologous ArfGAPs Participate in Coat Protein I-mediated Transport
        Akina Saitoh; Hye-Won Shin; Akane Yamada; Satoshi Waguri; Kazuhisa Nakayama
        JOURNAL OF BIOLOGICAL CHEMISTRY, May 2009, Peer-reviewed, Lead author
      • Differential Effects of Depletion of ARL1 and ARFRP1 on Membrane Trafficking between the trans-Golgi Network and Endosomes
        Kirika Nishimoto-Morita; Hye-Won Shin; Hiroko Mitsuhashi; Masashi Kitamura; Qian Zhang; Ludger Johannes; Kazuhisa Nakayama
        JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 2009, Peer-reviewed, Lead author
      • Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation
        Yuya Azuma; Mie Takada; Hye-Won Shin; Noriyuki Kioka; Kazuhisa Nakayama; Kazumitsu Ueda
        GENES TO CELLS, Feb. 2009, Peer-reviewed
      • Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes
        Ray Ishizaki; Hye-Won Shin; Hiroko Mitsuhashi; Kazuhisa Nakayama
        MOLECULAR BIOLOGY OF THE CELL, Jun. 2008, Peer-reviewed, Lead author
      • Recruitment of Tom1L1/Srcasm to Endosomes and the Midbody by Tsg101
        Yuko Yanagida-Ishizaki; Tomomi Takei; Ray Ishizaki; Hitoshi Imakagura; Senye Takahashi; Hye-Won Shin; Yohei Katoh; Kazuhisa Nakayama
        CELL STRUCTURE AND FUNCTION, 2008, Peer-reviewed
      • Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1
        Tomoo Shiba; Hiroshi Koga; Hye-Won Shin; Masato Kawasaki; Ryuichi Kato; Kazuhisa Nakayama; Soichi Wakatsuki
        Proceedings of the National Academy of Sciences of the United States of America, 17 Oct. 2006, Peer-reviewed
      • AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors
        Ray Ishizaki; Hye-Won Shin; Sanae M. M. Iguchi-Ariga; Hiroyoshi Ariga; Kazuhisa Nakayama
        GENES TO CELLS, Aug. 2006, Peer-reviewed
      • Erratum: Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells (Journal of Neurochemistry (2005) 93 (674-85))
        Shigetsune Matsuya; Hiroyuki Sakagami; Akira Tohgo; Yuji Owada; Hye-Won Shin; Hiroshi Takeshima; Kazuhisa Nakayama; Shoichi Kokubun; Hisatake Kondo
        Journal of Neurochemistry, Nov. 2005, Peer-reviewed
      • Roles of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane trafficking
        HW Shin; H Kobayashi; M Kitamura; S Waguri; T Suganuma; Y Uchiyama; K Nakayama
        JOURNAL OF CELL SCIENCE, Sep. 2005, Peer-reviewed, Lead author
      • An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
        HW Shin; M Hayashi; S Christoforidis; S Lacas-Gervais; S Hoepfner; MR Wenk; J Modregger; S Uttenweiler-Joseph; M Wilm; A Nystuen; WN Frankel; M Solimena; P De Camilli; M Zerial
        JOURNAL OF CELL BIOLOGY, Aug. 2005, Peer-reviewed, Lead author
      • Role of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane traffic
        Kitamura Masashi; Shin Hye-Won; Kobayashi Hiromi; Waguri Satoshi; Uchiyama Yasuo; Nakayama Kazuhisa
        CELL STRUCTURE AND FUNCTION, Jun. 2005, Peer-reviewed
      • Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells
        S Matsuya; H Sakagami; A Tohgo; Y Owada; HW Shin; H Takeshima; K Nakayama; S Kokubun; H Kondo
        JOURNAL OF NEUROCHEMISTRY, May 2005, Peer-reviewed
      • Expression of BIG2 and analysis of its function in mammalian cells
        HW Shin; C Shinotsuka; K Nakayama
        GTPASES REGULATING MEMBRANE DYNAMICS, 2005, Peer-reviewed
      • Roles of BIG family proteins in membrane trafficking
        HW Shin; R Ishizaki; K Nakayama
        YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2005, Peer-reviewed
      • Expression of BIG2 and analysis of its function in mammalian cells
        HW Shin; C Shinotsuka; K Nakayama
        GTPASES REGULATING MEMBRANE DYNAMICS, 2005, Peer-reviewed
      • BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: Its localization to recycling endosomes and implication in the endosome integrity
        HW Shin; N Morinaga; M Noda; K Nakayama
        MOLECULAR BIOLOGY OF THE CELL, Dec. 2004, Peer-reviewed, Lead author
      • Guanine nucleotide-exchange factors for Arf GTPases: Their diverse functions in membrane traffic
        HW Shin; K Nakayama
        JOURNAL OF BIOCHEMISTRY, Dec. 2004, Peer-reviewed, Invited, Lead author
      • Dual control of membrane targeting by Ptdlns(4)P and ARF
        HW Shin; K Nakayama
        TRENDS IN BIOCHEMICAL SCIENCES, Oct. 2004, Peer-reviewed, Invited, Lead author
      • GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination
        Y Shiba; Y Katoh; T Shiba; K Yoshino; H Takatsu; H Kobayashi; HW Shin; S Wakatsuki; K Nakayama
        JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2004, Peer-reviewed
      • GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination
        Y Shiba; Y Katoh; T Shiba; K Yoshino; H Takatsu; H Kobayashi; HW Shin; S Wakatsuki; K Nakayama
        JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2004, Peer-reviewed
      • Phosphoinositides regulate membrane-dependent actin assembly by latex bead phagosomes
        H Defacque; E Bos; B Garvalov; C Barret; C Roy; P Mangeat; HW Shin; Rybin, V; G Griffiths
        MOLECULAR BIOLOGY OF THE CELL, Apr. 2002, Peer-reviewed
      • gamma-adaptin interacts directly with rabaptin-5 through its ear domain
        Y Shiba; H Takatsu; HW Shin; K Nakayama
        JOURNAL OF BIOCHEMISTRY, Mar. 2002, Peer-reviewed
      • Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: Analysis using yeast three-hybrid system
        H Takatsu; M Futatsumori; K Yoshino; Y Yoshida; HW Shin; K Nakayama
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jun. 2001, Peer-reviewed
      • Identification and characterization of novel isoforms of COPI subunits
        M Futatsumori; K Kasai; H Takatsu; FW Shin; K Nakayama
        JOURNAL OF BIOCHEMISTRY, Nov. 2000, Peer-reviewed
      • Dynamin II is involved in endocytosis but not in the formation of transport vesicles from the trans-Golgi network
        K Kasai; HW Shin; C Shinotsuka; K Murakami; K Nakayama
        JOURNAL OF BIOCHEMISTRY, Apr. 1999, Peer-reviewed
      • Intermolecular and interdomain interactions of a dynamin-related GTP-binding protein, Dnm1p/Vps1p-like protein
        HW Shin; H Takatsu; H Mukai; E Munekata; K Murakami; K Nakayama
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 1999, Peer-reviewed, Lead author
      • Identification and characterization of novel clathrin adaptor-related proteins
        H Takatsu; M Sakurai; HW Shin; K Murakami; K Nakayama
        JOURNAL OF BIOLOGICAL CHEMISTRY, Sep. 1998, Peer-reviewed
      • Identification and subcellular localization of a novel mammalian dynamin-related protein homologous to yeast Vps1p and Dnm1p
        HW Shin; C Shinotsuka; S Torii; K Murakami; K Nakayama
        JOURNAL OF BIOCHEMISTRY, Sep. 1997, Peer-reviewed, Lead author

      Misc.

      • Regulation mechanism of phosphatidylserine-flippase at the plasma membrane
        Hye-Won Shin; Hiroyuki Takatsu
        Seikagaku, 2018, Invited, Lead author, Corresponding author
      • Membrane curvature generation by transbilayer lipid flip-flop
        Hye-Won Shin
        実験医学, 2018, Invited
      • Roles of small GTPases and BAR domain proteins in post-Golgi membrane traffic
        Hye-Won Shin; Zhiqiu Man; Kazuhisa Nakayama
        Seikagaku, 2012, Invited
      • Roles of the Arf family of small GTPases in membrane traffic
        Kazuhisa Nakayama; Hye-Won Shin
        タンパク質核酸酵素, Dec. 2008, Invited
      • ARFによるメンブレントラフィックの調節 (特集 メンブレントラフィック研究の新局面--いま明かされる細胞内輸送の仕組み)
        申 惠媛; 中山 和久
        細胞工学, Nov. 2006
      • Regulation of membrane trafficking by ARFs
        Hye-Won Shin; Kazuhisa Nakayama
        細胞工学, 2006, Invited
      • Analyses of interaction of FlP3 and FIP4 with Rab11 and ARFs and their roles in membrane traffic
        Hiroshi Koga; Hye-Won Shin; Kazuhisa Nakayama
        CELL STRUCTURE AND FUNCTION, Jun. 2005
      • Coordinated recruitment of Rab5, EEA1, type II inositol 5-phosphatase and type I inositol 4-phosphtase to peripheral ruffles in serum stimulated astrocytes.
        M Hayashi; H Shin; S Lacas-Gervais; M Wenk; J Modregger; A Nystuen; WN Frankel; M Solimena; M Zerial; P De Camilli
        MOLECULAR BIOLOGY OF THE CELL, Nov. 2004
      • An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
        H Shin; M Hayashi; S Christoforidis; S Lacas-Gervais; M Wenk; M Solimena; P De Camilli; M Zerial
        MOLECULAR BIOLOGY OF THE CELL, Nov. 2004
      • BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: Its localization to recycling endosomes and implication in the endosome integrity
        K Nakayama; H Shin
        MOLECULAR BIOLOGY OF THE CELL, Nov. 2004
      • BIG2 function on the endosomal compartment
        Hye-Won Shin; Kazuhisa Nakayama
        CELL STRUCTURE AND FUNCTION, May 2004
      • Vesicle fusion and tethering mechanism in Golgi complex
        中村暢宏; 吉村信一郎; 申 惠媛
        実験医学, 2003, Invited
      • タンパク質の輸送と細胞内局在、タンパク質がわかる
        中山和久; 申惠媛; 中村暢宏
        わかる実験医学シリーズ, 2003
      • Rab5-regulated phosphoinositides synthesis and turnover and its cellular function
        H Shin; S Christoforidis; M Zerial
        MOLECULAR BIOLOGY OF THE CELL, Nov. 2002
      • gamma-Adaptin interacts directly with Rabaptin-5 through its ear domain
        K Nakayama; Y Shiba; H Takatsu; HW Shin
        MOLECULAR BIOLOGY OF THE CELL, Dec. 2000

      Presentations

      • Mechanism of cellular localization of lipid flippases
        Hye-Won Shin
        大阪大学タンパク質研究所セミナー生体膜上の生物化学, 05 Mar. 2021, Invited
      • Effect of temperature, ion and nucleotide on ATP8A1 and SERCA1a reaction mechanism
        安田哲; 山崎和生; 大保貴嗣; 高津宏之; 申 惠媛; Stefania Danko; 川辺淳一; 鈴木裕
        第93回日本生化学会大会
      • Mechanism of cellular localization of lipid flippases
        Hye-Won Shin
        第93回日本生化学会大会, Invited
      • Membrane curvature generation by phospholipid flippase
        Hye-Won Shin
        日本薬学会第140年会, Invited
      • Plasma membrane deformation by phospholipid flippase and cellular functions
        SHIN Hye-Won
        The 57th Annual Meeting of The Biophysical Society of Japan, 24 Sep. 2019, Invited
      • Regulation mechanism of transbilayer lipid transport by P4-ATPase
        SHIN Hye-Won
        The 92nd Annual Meeting of The Japanese Biochemical Society, 18 Sep. 2019, Invited
      • リン脂質フリッパーゼATP11Cとezrinの相互作用
        井上寛己; 高津宏之; 高山真裕; 濵本明日香; 中山和久; 申 惠媛
        第92回日本生化学会大会, Sep. 2019
      • P4-ATPaseによるグルコシルセラミドの輸送と生理的意義
        高津宏之; 内藤朋樹; Siddabasavegowda; Bommegowda; 有田誠; 中山和久; 申 惠媛
        第92回日本生化学会大会, Sep. 2019
      • Dynamic localization mechanism of lipid flippases and their functions in mammalian cells
        SHIN Hye-Won
        2019 Molecular and Cellular Biology Gordon Research Conference, 28 Jul. 2019, Invited
      • リン脂質フリッパーゼによる生体膜ダイナミックス
        申 惠媛
        2019年生理学研究所研究科(分泌研究の新展開:その普遍性と多様性), 06 Jun. 2019, Invited
      • 膜脂質フリッパーゼの基質多様性と生理的意義
        内藤朋樹; 高津宏之; 高田直人; 中山和久; 申 惠媛
        第19回日本タンパク質科学会年会・第71回日本細胞生物学会大会 合同年次大会, Jun. 2019
      • リン脂質フリッパーゼATP11C(b)の極性局在と活性化型ezrinとの関係
        濵本明日香; 井上寛己; 高津宏之; 中山和久; 申 惠媛
        第66回日本生化学会近畿支部例会, May 2019
      • Membrane dynamics and phospholipid flippase activity
        Hye-Won Shin
        Membrane Lipid Transporter Symposium 2018, 27 Sep. 2018, Invited
      • Plasma membrane shape changes by phospholipid flipping activity
        Hye-Won Shin
        The 91st Annual Meeting of the Japan Biochemical Society, 24 Sep. 2018, Invited
      • ピコ秒時間けい光分光法による人工脂質二重膜と細胞膜の粘度分布の比較
        林春菜; 高田直人; 高門輝; 高屋智久; 申 惠媛; 岩田耕一
        第12回分子科学討論会, Sep. 2018
      • リン脂質フリッパーゼ発現による細胞膜の粘度への影響
        林春菜; 高田直人; 高門輝; 高屋智久; 申 惠媛; 岩田耕一
        第56回日本生物物理学会, Sep. 2018
      • リン脂質フリッパーゼATP8A1の反応と安定性に対する界面活性剤および脂質の影響
        安田哲; 山崎和生; 大保貴嗣; 高津宏之; 申 惠媛; Stefania Danko; 鈴木裕
        第91回日本生化学会大会, Sep. 2018
      • P4-ATPaseの細胞内局在におけるATPase反応サイクルの関与
        刀根卓也; 高津宏之; 中山和久; 申 惠媛
        第91回日本生化学会大会, Sep. 2018
      • リン脂質フリッパーゼATP11Cとezrinの相互作用
        井上寛己; 高津宏之; 高山真裕; 中山和久; 申 惠媛
        第91回日本生化学会大会, Sep. 2018
      • 脂質フリッパーゼP4-ATPaseの細胞内局在におけるN末およびC末領域の機能
        岡本小百合; 内藤朋樹; 中山和久; 高津宏之; 申 惠媛
        第91回日本生化学会大会, Sep. 2018
      • リン脂質フリッパーゼATP11CのC末バリアントの特性
        高津宏之; 高山真裕; 井上寛己; 中山和久; 申 惠媛
        第91回日本生化学会大会, Sep. 2018
      • Regulation mechanism of the phosphatidylserine flippase ATP11C
        SHIN Hye-Won
        Joint Annual Meeting of JSDB 51st and JSCB 70th, 05 Jun. 2018
      • N- or C-terminal cytoplasmic regions of class 5 and class 6 P4-ATPases are responsible for their subcellular localization
        Okamoto, S; Naito, T; Nakayama, K; Takatsu, H; Shin, H.-W
        Joint Annual Meeting of JSDB 51st and JSCB 70th, Jun. 2018
      • Polarized localization of the phospholipid flippase ATP11C isoform at the plasma membrane
        Takayama, M; Inoue, H; Nakayama, K; Takatsu, H; Shin, H.-W
        第70回日本細胞生物学会・第51回日本発生生物学会合同大会, Jun. 2018
      • ピコ秒時間けい光分光法を用いた細胞膜の粘度評価
        林春菜; 高田直人; 高門輝; 高屋智久; 申 惠媛; 岩田耕一
        第43回日本分光学会, Jun. 2018
      • 細胞膜脂質フリッパーゼの基質特異性と活性調節メカニズム
        申 惠媛
        大阪大学蛋白質研究所セミナー生体膜上の生物化学2018, 01 Mar. 2018, Invited
      • P4-ATPaseのPKCによる制御機構
        申 惠媛
        日本生体エネルギー研究会第42回討論会, 20 Dec. 2017
      • フリッパーゼの生化学的反応機構の解析
        安田哲; 山崎和生; 大保貴嗣; 高津宏之; 申惠媛; Stefania Danko; 鈴木裕
        ConBio2017, Dec. 2017
      • リン脂質フリッパーゼATP11Cのスプライシングバリアント間の機能的相違
        高山真裕; 高津宏之; 中山和久; 申惠媛
        ConBio2017, Dec. 2017
      • 非アポトーシス細胞におけるリン脂質フリッパーゼATP11Cの制御機構
        高津宏之; 高山真裕; 中山和久; 申惠媛
        ConBio2017, Dec. 2017
      • 脂質フリッパーゼの新奇基質としてグルコシルセラミドの発見とその輸送メカニズム
        内藤朋樹; Bartholomew; P. Roland; Todd R. Graham; 申惠媛
        ConBio2017, Dec. 2017
      • リン脂質フリップ活性が誘導する膜変形
        高田直人; 内藤朋樹; 井上尊生; 中山和久; 申惠媛
        ConBio2017, Dec. 2017
      • Specific substrates for P4-ATPases and their regulation in mammalian cells.
        SHIN Hye-Won
        The 15th International Conference on Na, K-ATPase and Related Transport ATPases, 24 Sep. 2017, Invited
      • 一定の深さにおける細胞膜粘度評価法の開発
        林春菜; Manjusha Josh; 高田直人; 高屋智久; 中村浩之; 申惠媛; 岩田耕一
        第11回分子化学討論会, Sep. 2017
      • Identification of mammalian glucosylceramide flippase and analysis of its transport mechanism
        Tomoki Naito; Bart Roland; Todd Graham; Hye-Won Shin
        The 15th International Conference on Na, K-ATPase and Related Transport ATPases, Sep. 2017
      • Phorbol ester処理によるリン脂質フリッパーゼATP11Cの局在変化
        高山真裕; 高津宏之; 中山和久; 申 惠媛
        生体運動合同班会議2017, Jan. 2017
      • P4-ATPaseのリン脂質flippase活性と細胞機能の調節
        申 惠媛
        日本生体エネルギー研究会第41回討論会, 22 Dec. 2016
      • Regulation mechanism of P4-ATPase by membrane traffic
        Hye-Won Shin
        The 89th Annual Meeting of the Japanese Biochemical Society, 27 Sep. 2016, Invited
      • リン脂質フリッパーゼATP11CのPKCによる制御機構.
        高津宏之; 高山真裕; 中山和久; 申 惠媛
        第89回日本生化学会大会, Sep. 2016
      • P4-ATPaseによるリン脂質フリップが膜変形に与える影響.
        高田直人; 中山和久; 申 惠媛
        第89回日本生化学会大会., Sep. 2016
      • 細胞内リサイクリング経路におけるリン脂質フリッパーゼの機能解析.
        田中祥城; 小野夏生; 中山和久; 申 惠媛
        生体運動合同班会議2016, Jan. 2016
      • 細胞膜ホスファチジルコリンのフリップ・フロップと胆汁うっ滞症の関係
        田中雅久; 高津宏之; 中山和久; 申 惠媛
        生体運動合同班会議2016, Jan. 2016
      • COPI被服小胞を介するSCAP-SREBP複合体のゴルジ体から小胞体への逆行輸送による脂質代謝の調節
        船橋輝記; 高島昭平; 齋藤明奈; 廣瀬祥平; 申 惠媛; 中山和久
        第88回日本生化学会大会・第38回日本分子生物学会年会合同大会, 01 Dec. 2015
      • ホスファチジルセリン取り込み異常のCHO-K1変異株(UPS-1)におけるflippaseの発現解析
        高田直人; 高津宏之; 宮野吏永; 中山和久; 申 惠媛
        第88回日本生化学会大会・第38回日本分子生物学会年会合同大会, 01 Dec. 2015
      • Phospholipid flippase activities and substrate specificities of P4-ATPases and their roles in cellular function
        Hye-Won Shin
        The 53rd Annual meeting of The Biophysical Society of Japan, 15 Sep. 2015, Invited
      • リン脂質フリッパーゼATP10AのPCフリップ活性及び細胞膜ダイナミクスへの関与
        内藤朋樹; 高津宏之; 宮野吏永; 高田直人; 中山和久; 申 惠媛
        第14回次世代を担う若手ファーマ・バイオフォーラム2015, 12 Sep. 2015
      • Subcellular localization and phospholipid flippase activity of class 5 P4-ATPases.
        Naito, T; Takatsu, H; Nakayama, K; Shin, H.-W
        18th iCeMS International Symposium & 15th International Membrane Research Forum, Mar. 2015
      • リン脂質フリッパーゼATP10Aのフリップ活性及び細胞膜ダイナミクスへの関与
        内藤朋樹; 高津宏之; 宮野吏永; 高田直人; 中山和久; 申 惠媛
        第62回日本生化学会近畿支部例会, 2015
      • ATP8B1 (familial intrahepatic cholestasis 1) translocates phosphatidylcholine at the plasma membrane.
        Takatsu, H; Tanaka, G; Nakayama, K; Shin, H.-W
        18th iCeMS International Symposium & 15th International Membrane Research Forum, 2015
      • P4-ATPaseによるリン脂質の量的・質的変容と膜変形を伴う細胞機能の関係.
        申 惠媛
        第87回日本生化学会大会, Oct. 2014, Invited
      • P4-ATPaseによる細胞ー細胞外マトリックス間接着の調節機構の解明
        宮野吏永; 高津宏之; 中山和久; 申 惠媛
        第13回次世代を担う若手ファーマ・バイオフォーラム2014, 2014
      • ATP8B1とABCB4の協調的なリン脂質のフリップ・フロップと新構成家族性肝内胆汁うっ滞症の関係
        田中雅久; 高津宏之; 中山和久; 申 惠媛
        第87回日本生化学会大会, 2014
      • クラス5 P4-ATPaseの細胞内局在およびリン脂質フリップ活性
        内藤朋樹; 高津宏之; 中山和久; 申 惠媛
        第87回日本生化学会大会, 2014
      • COPI被服小胞を介するSREBP-SCAP複合体のゴルジ体から小胞体への逆行輸送
        船橋輝記; 高島昭平; 齋藤明奈; 廣瀬祥平; 申 惠媛; 中山和久
        第87回日本生化学会大会, 2014
      • ホスファチジルコリンのフリップーフロップの相関性の破綻とPFIC(新構成家族性肝内胆汁うっ滞症)
        高津宏之; 田中雅久; 中山和久; 申 惠媛
        第87回日本生化学会大会シンポジウム, 2014, Invited
      • リサイクリングエンドソームを介する輸送経路におけるタンパク質とリン脂質の協調的作用.
        申 惠媛
        第86回日本生化学会大会, Sep. 2013, Invited
      • Membrane remodeling in post-Golgi trafficking
        Hye-Won Shin
        The 65th Annual Meeting of the Japan Society for Cell Biology, Jun. 2013, Invited
      • ATP8B1 (FIC1, familial intrahepatic cholestasis 1)はホスファチジルコリンのフリッパーゼである
        高津宏之; 中山和久; 申 惠媛
        第86回日本生化学会大会, Mar. 2013
      • P4-ATPaseの細胞内小胞輸送における機能解析
        小野夏生; 高津宏之; 中山和久; 申 惠媛
        第12回次世代を担う若手ファーマ・バイオフォーラム2013, 2013
      • Interplay of lipids and proteins in intracellular membrane traffic
        SHIN Hye-won
        第2回発生細胞生物学ミニワークショップ, Nov. 2012, Invited
      • 生体膜の非対称性を制御するP4-ATPaseの小胞輸送における機能
        Hye-Won Shin
        第34回生体膜の薬物の相互作用シンポジウム, Nov. 2012
      • ゴルジ体ー小胞体間のタンパク質輸送による脂肪滴形成の調節
        高島昭平; 齋藤明奈; 廣瀬祥平; 申 惠媛; 中山和久
        第85回日本生化学会大会, 2012
      • 生体膜の脂質非対称性を調節するP4-ATPaseのゴルジ体以降の小胞輸送経路における機能解析
        海野寛之; 高津宏之; 中山和久; 申 惠媛
        第85回日本生化学会大会, 2012
      • Revisiting roles of the Golgi-localizing small GTPase ARFs
        Hye-Won Shin
        The 84th Annual Meeting of Japanese Biochemical Society, Sep. 2011, 日本生化学会, Invited
      • Functional analysis of the small GTPase Arf6 during Cytokinesis
        正親美菜子; 武井朋美; 高橋千絵; 申 惠媛; 中山和久
        第63回日本細胞生物学会大会, 2011
      • Arfaptins localize to the trans-Golgi in an Arl1-dependent manner and deform Golgi membranes
        満 智秋; 申 惠媛; 中山和久
        第63回日本細胞生物学会大会, 2011
      • Regulation of lipid droplet formation by Golgi-to-ER membrane traffic
        高島皓平; 齋藤明奈; 申 惠媛; 中山和久
        第63回日本細胞生物学会大会, 2011
      • Functional analysis of class I and classII ARF small GTPases in membrane traffic
        中井和香; 近藤由美香; 齋藤明奈; 中山和久; 申 惠媛
        第63回日本細胞生物学会大会, 2011
      • ゴルジ体‐小胞体間のタンパク質輸送による脂肪滴形成の調節
        高島昭平; 齋藤明奈; 廣瀬祥平; 申 惠媛; 中山和久
        第84回日本生化学会大会, 2011
      • 脂質二重層の非対称性を調節するP4-ATPaseのメンブレントラフィックにおける役割
        島孝弘; 馬場啓子; 高津宏之; 海野寛之; 中山和久; 申 惠媛
        第84回日本生化学会大会, 2011
      • メンブレントラフィックにおけるP4-ATPase、ATP9Bの機能解析
        高津宏之; 馬場啓子; 海野寛之; 島孝弘; 中山和久; 申 惠媛
        第84回日本生化学会大会, 2011
      • 細胞分裂時のトランスフェリン受容体と鉄輸送体DMT1の局在変化
        高津宏之; 加藤洋平; 上田智子; 高橋千絵; 申 惠媛; 中山和久
        フォーラム:衛生薬学・環境トキシコロジー, 2011
      • 細胞質分裂時のRab11-FIP3/Arfophilin-1の局在調節におけるRab11とArf6の異なる役割
        高橋千絵; 武井朋美; 古賀裕士; 高津宏之; 申 惠媛; 中山和久
        第22回生体膜と薬物の相互作用シンポジウム, 2011
      • Functional crosstalk between Rab14 and Rab4 through a dual effector, RUFY1/Rabip4
        Yamamoto, H; Koga, H; Katoh, Y; Takahashi, S; Nakayama, K; Shin, H.-W
        50th Annual Meeting of the American Society for Cell Biology, Dec. 2010
      • 細胞内小胞輸送におけるARF4とARF5の機能解析
        中井和香; 齋藤明奈; 近藤由美香; 中山和久; 申 惠媛
        第33回日本分子生物学会年会・第83回日本生化学会大会合同大会, Dec. 2010
      • ゴルジ体-小胞体間のタンパク質輸送による脂肪滴形成の調節
        高島皓平; 齋藤明菜; 申 惠媛; 中山和久
        第33回日本分子生物学会年会・第83回日本生化学会大会合同大会, Dec. 2010
      • Mitosis-Coupled Sequestration of Recycling Endosomes around Spindle Pole Centrosomes
        Nakayama, K; Takatsu, H; Ueda, T; Waguri, S; Takahashi, S; Kondo, Y; Shin, H.-W
        第33回日本分子生物学会年会・第83回日本生化学 会大会合同大会, Dec. 2010, Invited
      • Rab11とExocyst複合体による膜リサイクリングの調節
        高橋千絵; 申 惠媛; 中山和久
        第32回生体膜と薬物の相互作用シンポジウム, Nov. 2010
      • 生体膜リン脂質非対称性を司るフリッパーゼの細胞内局在
        馬場啓子; 申 惠媛; 中山和久
        ファーマ・バイオフォーラム2010, Oct. 2010
      • エンドソームを介する小胞輸送経路におけるArf1とArf3の機能解析
        近藤由美香; 申 惠媛; 中山和久
        ファーマ・バイオフォーラム2010, Oct. 2010
      • Roles of Small GTPase ARF1 and ARF3 in recycling endosomes
        Hye-Won Shin
        FASEB Summer Research Conference, “Arf Family G Proteins”, Aug. 2010
      • 低分子量GTPaseであるARF1とARF3はり策リング経路で機能する
        近藤由美香; 申 惠媛; 中山和久
        第62回日本細胞生物学会大会, May 2010
      • 細胞質分裂における低分子量GTPase ARF6の機能の解析
        正親美菜子; 武井朋美; 高橋千絵; 申 惠媛; 中山和久
        第62回日本細胞生物学会大会, May 2010
      • 細胞質分裂におけるArf6およびEFA6 (Arf6-GEF) の局在と機能
        上田智子; 近藤由美香; 申 惠媛; 中山和久
        第62回日本細胞生物学会大会, May 2010
      • ArfaptinのArl1依存的なトラスゴルジへの局在とArfaptinによるゴルジ体チューブル構造の形成
        満 智秋; 近藤由美香; 申 惠媛; 中山和久
        第62回日本細胞生物学会大会, May 2010
      • CRESCent: Cluster of Recycling Endosomes Transiently Formed around Spindle Pole Centrosome
        Takatsu, H; Ueda, T; Waguri, S; Takahashi, S; Kondo, Y; Shin, H.-W; Nakayama, K
        49th Annual Meeting of the American Society for Cell Biology, Dec. 2009
      • Arfのグアニンヌクレオチド交換因子BIG1とBIG2のトラスゴルジ網局在化機構の解析
        高島皓平; 申 惠媛; 中山和久
        ファーマ・バイオフォーラム2009, Nov. 2009
      • メンブレントラフィックにおけるArfaptinの機能解析
        満 智秋; 申 惠媛; 中山和久
        ファーマ・バイオフォーラム2009, Nov. 2009
      • 細胞質分裂時のArf6およびEFA6 (Arf6-GEF) の局在変化
        上田智子; 武井朋美; 申 惠媛; 坂上洋行; 中山和久
        ファーマ・バイオフォーラム2009, Nov. 2009
      • RabファミリーとArfファミリーの低分子量GTPaseによる細胞質分裂の調節
        中山和久; 高橋千絵; 武井朋美; 上田智子; 高津宏之; 申 惠媛
        第82回日本生化学会大会, Oct. 2009, Invited
      • 分裂期間および細胞分裂時のFIP3/FIP4の局在化におけるRab11およびArf6の役割
        高橋千絵; 武井朋美; 古賀裕士; 申 惠媛; 中山和久
        第82回日本生化学会大会, Oct. 2009
      • 細胞質分裂時のArf6およびEFA6 (Arf6-GEF) の局在変化
        上田智子; 武井朋美; 申 惠媛; 坂上洋行; 中山和久
        第82回日本生化学会大会, Oct. 2009
      • 細胞質分裂における低分子量GTPase ARF6の機能の解析
        武井朋美; 高橋千絵; 申 惠媛; 中山和久
        第61回日本細胞生物学会大会, Jun. 2009
      • 細胞分裂におけるリサイクリングエンドソームの動態
        高津宏之; 上田智子; 近藤由美香; 申 惠媛; 中山和久
        第61回日本細胞生物学会大会, Jun. 2009
      • ARFGAP1, 2, 3はCOPI被覆小胞を介する輸送経路で働く
        齋藤明奈; 申 惠媛; 山田茜; 和栗聡; 中山和久
        第61回日本細胞生物学会大会, Jun. 2009
      • メンブレントラフィックにおけるArfaptin/PORの機能研究
        満智秋; 申 惠媛; 中山和久
        第61回日本細胞生物学会大会, Jun. 2009
      • リソソーム分解経路における低分子量GTPase ARF3の機能
        申 惠媛; 近藤由美香; 中山和久
        第61回日本細胞生物学会大会, Jun. 2009
      • 低分子量GTPaseによるリサイクリングエンドソーム機能と細胞質分裂 の調節
        中山和久; 高橋千絵; 武井朋美; 高津宏之; 申惠媛
        第31回日本分子生物学会年会・第81回日本生化学会 大会合同大会, Dec. 2008, Invited
      • Arfのグアニンヌクレオチド交換因子BIG1とBIG2のトランスゴルジ網への局在機構の解析
        高島皓平; 申惠媛; 中山和久
        第31回日本分子生物学会年会・第81回日本生化学会 大会合同大会, Dec. 2008
      • 細胞内小胞輸送における低分子量GTPase Rab14の役割
        山本昆明; 申惠媛; 中山和久
        第31回日本分子生物学会年 会・第81回日本生化学会大会合同大会, Dec. 2008
      • 細胞内小胞輸送における新規ARF-GAPの機能解析
        齋藤明奈; 申惠媛; 中山和久
        ファー マ・バイオフォーラム2008, Nov. 2008
      • 細胞質分裂における低分子量GTPase Arf6の機能の解析
        武井朋美; 高橋千絵; 申惠媛; 中山和久
        ファー マ・バイオフォーラム2008, Nov. 2008
      • ARL1 and ARFRP1 independently regulate membrane trafficking ‘to’ and ‘from’ the TGN
        Shin, H.-W; Nishimoto, K; Nakayama, K
        The 2008 Golgi meeting, Sep. 2008
      • 細胞内小胞輸送におけるArfGAP1,2,3の役割
        齋藤明奈; 申惠媛; 中山和久
        第60回日本細胞生物学会大会, Jun. 2008
      • メンブレントラフィックにおけるArfaptin/POR の機能研究
        満智秋; 申恵媛; 中山和久
        第60 回日本細胞生物学会大会, Jun. 2008
      • ARFRP1とARL1によるTGN 以降の膜輸送の調節
        申惠媛; 西本樹理加; 中山和久
        第60 回日本細胞生物学会大会, Jun. 2008
      • エンドサイトー シスにおける低分子量GTPase ARF1/3 の役割
        申惠媛; 石崎玲; 中山和久
        第30回日本 分子生物学会年会・第80回日本生化学会大会合同大会, Dec. 2007
      • ポストゴルジ輸送におけるArl1 の役割
        西本樹理加; 申惠媛; 中山和久
        第30回日本分子生物学会年 会・第80回日本生化学会大会合同大会, Dec. 2007
      • ARF のグアニンヌクレオチド交換因子BIG1 とBIG2 の発現抑制による機能 解析
        石崎玲; 申惠媛; 中山和久
        第30回日本分 子生物学会年会・第80回日本生化学会大会合同大会, Dec. 2007
      • 細胞内小胞輸 送における低分子量GTPase Rab14 の役割
        山本昆明; 申惠媛; 中山和久
        第30回日本分子生物学会年会・第80回日本生化学会大会合同大会, Dec. 2007
      • ARFRP1 and ARL1 independently regulate membrane trafficking ‘from’ and ‘to’ the TGN
        Nakayama, K; Nishimoto, K; Man, Z; Shin, H.-W
        International Symposium on Membrane Traffic, Nov. 2007
      • Functional analysis of novel ARF-GAPs in membrane traffic. International Symposium on Membrane Traffic
        Saitoh, A; Shin, H.-W; Nakayama, K
        International Symposium on Membrane Traffic, Nov. 2007
      • Redundant roles of BIG2 and BIG1 in membrane traffic between the TGN and endosomes
        Ishizaki, R; Shin, H.-W; Nakayama, K
        International Symposium on Membrane Traffic, Nov. 2007
      • Distinct and redundant functions of BIG1 and BIG2 in TGN and recycling endosome.
        SHIN Hye-won
        FASEB Summer Research/CNRS Conference, Jun. 2007, Invited
      • Rab11とARFのエフェクター,Rab11-FIP/Arfophilinのメンブレントラフィックにおける機能
        古賀裕士; 申惠媛; 張茜; 中山和久
        第40回日本発生生物学会・第59回日本細胞生物学会合同大会, May 2007
      • Distinct and redundant functions of BIG1 and BIG2 in the TGN and recycling endosomes
        Ishizaki, R; Shin, H.-W; Nakayama, K
        第10回細胞膜研究フォーラム, Feb. 2007
      • Dual Interaction of Arfophilins/Rab11-FIPs with ARFs and Rab11
        Koga, H; Shin, H.-W; Nakayama, K
        46th Annual Meeting of the American Society for Cell Biology, Dec. 2006
      • 低分子量GTPase ARFRP1の機能解析
        北村雅史; 申惠媛; 中山和久
        日本分子生物学会2006フォーラム, Dec. 2006
      • 細胞内小胞輸送におけるArfGAP1~ArfGAP3の機能解析
        齋藤明奈; 申惠媛; 中山和久
        日本分子生物学会2006フォーラム, Dec. 2006
      • FIP3、FIP4によるRab11とARFの機能のクロスト ーク
        申 惠媛
        日本分子生物学会2006フォーラム, Dec. 2006, Invited
      • Rab5-regulated phosphoinositide turnover in the endocytic pathway.
        SHIN Hye-won
        18th Annual Meeting of the Korean Society for Molecular and Cellular Biology, Oct. 2006, Invited
      • Dual Interaction of Arfophilins/Rab11-FIPs with ADP-ribosylation factor and Rab11
        Koga, H; Shin, H.-W; Nakayama, K
        20th IUBMB International Congress of Biochemistry and Molecular Biology, Jun. 2006
      • Regulation of membrane trafficking between the TGN and endosomes by ARF-GEFs
        Nakayama, K; Shin, H.-W; Ishizaki, R
        20th IUBMB International Congress of Biochemistry and Molecular Biology, Jun. 2006
      • AMY-1 is localized on the trans-Golgi network in association with brefeldin A-inhibited guanine nucleotide-exchange factor 2 (BIG2)
        Ishizaki, R; Shin, H.-W; Iguchi-Ariga, S.M.M; Ariga, H; Nakayama, K
        第9回国 際細胞膜研究フォーラム, Mar. 2006
      • Dual interaction of Arfophilins/Rab11-FIPs with ADP-ribosylation factor and Rab11
        Koga, H; Shin, H.-W; Nakayama, K
        第9回国際細胞膜研究フォーラム, Mar. 2006
      • Roles of ARFRP1 (ADP-Ribosylation Factor-Related Protein 1) in Post-Golgi Membrane Trafficking
        Shin, H.-W; Kobayashi, H; Kitamura, M; Nakayama, K
        45th Annual Meeting of the American Society for Cell Biology, Dec. 2005
      • 細胞内膜輸送におけるBIGファミリータンパク質 の機能
        申惠媛; 石崎玲; 中山和久
        第27回生体膜と薬物の相互作用シンポジウム, Nov. 2005
      • BIG2, a Guanine Nucleotide Exchange Factor for ADP-Ribosylation Factors: Its Function at the Recycling Endosome
        Shin, H.-W; Ishizaki, R; Nakayama, K
        第78回日本生化学会大会, Oct. 2005
      • A New Method for Study of Post-Golgi Trafficking
        Zhang, Q; Shin, H.-W; Nakayama, K
        第78回日本生化学会大会, Oct. 2005
      • AMY-1 is localized on the trans-Golgi network in association with brefeldin A-inhibited guanine nucleotide-exchange factor 2 (BIG2)
        Ishizaki, R; Shin, H.-W; Iguchi-Ariga, S.M.M; Ariga, H; Nakayama, K
        第78回日本生化学会大会, Oct. 2005
      • BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: Its Function at the recycling endosome.
        申 惠媛
        第78回日本生化学会大会, Oct. 2005, Invited
      • Role of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane traffic
        Kitamura, M; Shin, H.-W; Kobayashi, H; Waguri, S; Uchiyama, Y; Nakayama, K
        第58回日本細胞生物学会大会, Jun. 2005
      • Analyses of interaction of FIP3 and FIP4 with Rab11 and ARFs and their roles in membrane traffic
        Koga, H; Shin, H.-W; Nakayama, K
        第58回日本細胞生物学会大会, Jun. 2005
      • BIG2, a Guanine Nucleotide Exchange Factor for ADP-Ribosylation Factors: Its Localization to Recycling Endosomes and Implication in the Endosome Integrity
        Nakayama, K; Shin, H.-W
        44th Annual Meeting of the American Society for Cell Biology, Dec. 2004
      • An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
        Shin, H.-W; Hayashi, M; Christoforidis; S; Lacas-Gervais, S; Wenk, M; Solimena, M; De Camilli, P; Zerial, M
        44th Annual Meeting of the American Society for Cell Biology, Dec. 2004
      • The subcellular localization and the role of ARF-related protein (ARF-RP)
        Shin, H.-W; Kobayashi, H; Nakayama, K
        第57回日本細胞生物学会大会, May 2004
      • BIG2 function on the endosomal compartment.
        Shin, H.-W; Kobayashi, H; Nakayama, K
        第57回日本細胞生物学会大会, May 2004
      • Rab5-regulated phosphoinositides synthesis and turnover and its cellular function
        Shin, H.-W; Christoforidis, S; Zerial, M
        42nd Annual Meeting of the American Society for Cell Biology, Dec. 2002
      • gamma-Adaptin interacts directly with Rabaptin-5 through its ear domain
        Nakayama, K; Shiba, Y; Takatsu, H; Shin, H.-W
        40th Annual meeting of American Society for Cell Biology, Dec. 2000
      • gamma-アダプチンとRabaptin5の相互作用の解析
        芝陽子; 高津宏之; 申 惠媛; 中山和久
        第73回日本生化学会大会, Oct. 2000
      • アダプター蛋白質複合体とCOP I複合体の形成は同様のサブユニット間相互作用により支配される
        吉野佳織; 高津宏之; 二ツ森睦美; 吉田雄作; 申 惠媛; 中山和久
        第73回日本生化学会大会, Oct. 2000
      • Self-association of Dnm1p/Vps1p-like protein (DVLP), a novel member of the dynamin GTPase family
        Shin, H.-W
        3rd Congress of the Asian-Pacific Organization for Cell Biology, Aug. 1998
      • 新奇ダイナミン様GTP結合蛋白質の同定と細胞内局在
        申 惠媛
        第50回日本細胞生物学会大会, Sep. 1997
      • Regulation of activity and localization of phosphatidylserine flippase, ATP11C
        Hiroyuki Takatsu; Hiroki Inoue; Masahiro Takayama; Hye-Won Shin
        Cell Bio virtual 2021
      • Mechanism of polarized localization of phospholipid flippase ATP11C
        Hiroki Inoue; Hiroyuki Takatsu; Hye-Won Shin
        第94回日本生化学会大会
      • ゴーシェ病患者の細胞にみられるリソソームの機能異常
        喜多夏暉; 濵本明日香; 高津宏之; 中山和久; 申 惠媛
        第42回生体膜と薬物の相互作用シンポジウム

      Books and Other Publications

      • レーニンジャ―新生化学:生化学と分子生物学の基本原理(第7版)
        申 惠媛, Joint translation, 第11章
        廣川書店, 2019, Not refereed
      • Dojin BioScience Series 24 メンブレントラフィック
        申 惠媛; 中山 和久, Joint work, Arfファミリーによるメンブレントラフィックの調節
        化学同人, 2016, Not refereed
      • レーニンジャ―新生化学:生化学と分子生物学の基本原理(第6版)
        申 惠媛, Joint translation, 第11章
        廣川書店, 2015, Not refereed
      • プロッパー細胞生物学:細胞の基本原理を学ぶ(第1版)
        申 惠媛, Joint translation, 第4章、第13章
        化学同人, 2013, Not refereed

      Media Coverage

      • Flipping lipids to deform membranes
        https://www.asbmb.org/asbmb-today/science/010720/flipping-lipids-to-deform-membranes, Jan. 2020, Pr
      • Kyodai sensei theater
        Kyoto Univ., 2019, Internet
      • Cells Flip Lipids To Bend Their Membranes
        https://www.asianscientist.com/2018/04/in-the-lab/atp10a-lipid-flip-membrane-deformation/, Apr. 2018, Internet
      • リン脂質の移動によって細胞膜が変形するメカニズムを解明
        https://www.kyoto-u.ac.jp/ja/research-news/2018-03-30, Mar. 2018, Internet
      • Flipping lipids for cell transport-tubules
        https://www.eurekalert.org/pub_releases/2018-03/ku-flf032818.php;https://phys.org/news/2018-03-flipping-lipids-cell-transport-tubules.html;https://www.sciencedaily.com/releases/2018/03/180329141014.htm, Mar. 2018, Internet
      • 京大、細胞膜の脂質輸送の仕組みの一端を解明
        https://www.nikkei.com/article/DGXLRSP463650_X11C17A1000000/?au=0, Nov. 2017, Internet
      • 細胞膜の脂質輸送、セロトニンやヒスタミンの受容体の仕組みの一端を解明
        https://www.kyoto-u.ac.jp/ja/research-news/2017-11-17-0, Nov. 2017, Internet

      External funds: Kakenhi

      • Physiological roles of lipid asymmetry in biological membranes mediated by lipid flippases
        Grant-in-Aid for Scientific Research (B)
        Basic Section 43030:Functional biochemistry-related
        Kyoto University
        申 惠媛
        From 01 Apr. 2020, To 31 Mar. 2023, Granted
        生体膜;P4-ATPase;フリッパーゼ
      • Relationship between architecture and function of intraciliary protein trafficking complex: molecular basis for ciliopathies
        Grant-in-Aid for Scientific Research (A)
        Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
        Kyoto University
        中山 和久
        From 01 Apr. 2019, To 31 Mar. 2024, Granted
        繊毛内タンパク質輸送;繊毛病;タンパク質間相互作用;CRISPR/CAS9システム;CRISPR/Cas9システム;繊毛
      • Regulation of enzymatic activities of P4-ATPases and its physiological function
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        Hye-Won Shin
        From 01 Apr. 2017, To 31 Mar. 2020, Project Closed
        生体膜;フリッパーゼ;脂質二重層;P4-ATPase;ホスファチジルセリン;細胞極性;エンドサイトーシス;細胞・組織;脂質
      • P4-ATPase-mediated dynamic ordering of phospholipids in biological membranes
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Science and Engineering
        Kyoto University
        申 惠媛
        From 01 Apr. 2016, To 31 Mar. 2018, Project Closed
        生体膜;リン脂質;フリッパーゼ;細胞・組織;脂質;脂質二重層
      • 膜運動におけるリン脂質の量的・質的変化の作用機序
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        申 惠媛
        From 01 Apr. 2015, To 31 Mar. 2017, Project Closed
        細胞膜;リン脂質;膜変形;生体膜;細胞・組織;脂質;脂質二重層;P4-ATPase
      • Transbilayer lipid asymmetry and cholestasis
        Grant-in-Aid for Scientific Research (C)
        Kyoto University
        Hye-Won Shin
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        生体膜;リン脂質;非対称性;細胞;胆汁酸;P4-ATPase;PFIC;胆汁うっ滞症;膜ダイナミクス;胆汁うっ滞
      • Functional crosstalk between ARF and Rab small GTPases
        Grant-in-Aid for Scientific Research (C)
        Kyoto University
        Hye-Won SHIN
        From 28 Apr. 2011, To 31 Mar. 2014, Project Closed
        メンブレントラフィック;小胞輸送;エンドソーム;生体膜;Gタンパク質;リサイクリング;低分子量GTPase;細胞;タンパク質
      • 生体膜の非対称性を制御するP4-ATPaseのメンブレントラフィックにおける役割
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        申 惠媛
        From 01 Apr. 2011, To 31 Mar. 2013, Project Closed
        メンブレントラフィック;脂質二重層;脂質非対称性;P4-ATPase;リン脂質
      • Regulatory mechanism of Rab14 and its effector proteins in post-Golgi membrane trafficking
        Grant-in-Aid for Young Scientists (B)
        Kyoto University
        Hye-Won SHIN
        Project Closed
        細胞;メンブレントラフィック;小胞輸送;低分子量GTPase;エンドソーム;低分量GTPase;Small GTPase
      • Regulation of membrane trafficking by small GTPase ARFRP1
        Grant-in-Aid for Young Scientists (B)
        Kyoto University
        Hye-won SHIN
        Project Closed
        小胞輸送;メンブレントラフィック;ゴルジ体;低分子量GTPase
      • Roles of multifunctional adaptor proteins, GGAs, in membrane traffic
        Grant-in-Aid for Scientific Research (A)
        Kyoto University
        Kazuhisa NAKAYAMA
        Project Closed
        細胞・組織;生体分子;蛋白質;薬学;GGA;GATドメイン;ユビキチン;小胞輸送;X線結晶構造解析;Tom1;Tollip, Cells and tissues;Biomolecules;Proteins;Pharmaceutical sciences
      • ゴルジ体を中心とするメンブレントラフィックの制御機構
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Kyoto University
        中山 和久
        Project Closed
        ARF;Rab;メンブレントラフィック;小胞輸送;細胞・組織;生体分子;蛋白質;薬学;BIG2;TGN;エンドソーム;GGA;Tom1;GATドメイン;ユビキチン;X線結晶構造解析
      list
        Last Updated :2022/05/14

        Education

        Teaching subject(s)

        • From Apr. 2011, To Mar. 2012
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Bioligical Chemistry 2 (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2013, To Mar. 2014
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2013, To Mar. 2014
          Introduction to Basic Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Basic Laboratory Techniques in Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Basic Laboratory Techniques in Biological Chemistry
          Fall, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Advanced Basic Biological Chemistry I
          Spring, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Global Frontier in Life Science A
          Spring, 生命科学研究科
        • From Apr. 2014, To Mar. 2015
          Bioligical Chemistry 2 (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2014, To Mar. 2015
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2014, To Mar. 2015
          Introduction to Basic Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Basic Laboratory Techniques in Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Basic Laboratory Techniques in Biological Chemistry
          Fall, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Global Frontier in Life Science A
          Spring, 生命科学研究科
        • From Apr. 2014, To Mar. 2015
          The Role of Life Science in Drug Discovery
          Spring, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Basic Laboratory Techniques in Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Basic Laboratory Techniques in Biological Chemistry
          Fall, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Introduction to Basic Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Advanced Basic Biological Chemistry I
          Spring, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Bioligical Chemistry 2 (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2015, To Mar. 2016
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2015, To Mar. 2016
          The Role of Life Science in Drug Discovery
          Spring, 全学共通科目
        • From Apr. 2016, To Mar. 2017
          ILAS Seminar
          Spring, 全学共通科目
        • From Apr. 2016, To Mar. 2017
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Basic Laboratory Techniques in Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Basic Laboratory Techniques in Biological Chemistry
          Fall, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Introduction to Basic Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Bioligical Chemistry 2 (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2016, To Mar. 2017
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2017, To Mar. 2018
          Introduction to Modern Life Sciences for Drug Discovery
          Spring, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Basic Laboratory Techniques in Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Basic Laboratory Techniques in Biological Chemistry
          Fall, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Bioligical Chemistry 2 (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2017, To Mar. 2018
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2018, To Mar. 2019
          Introduction to Modern Life Sciences for Drug Discovery
          Spring, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Basic Laboratory Techniques in Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Basic Laboratory Techniques in Biological Chemistry
          Fall, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Bioligical Chemistry 2 (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2018, To Mar. 2019
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2019, To Mar. 2020
          Laboratory Practice in Basic Physiological Chemistry
          Spring, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Laboratory Practice in Basic Physiological Chemistry
          Fall, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Research in Basic Physiological Chemistry
          Spring, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Research in Basic Physiological Chemistry
          Fall, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar in Basic Physiological Chemistry
          Spring, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar in Basic Physiological Chemistry
          Fall, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Basic Laboratory Techniques in Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Basic Laboratory Techniques in Biological Chemistry
          Fall, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Fundamental Chemical Experiments
          Fall, 全学共通科目
        • From Apr. 2019, To Mar. 2020
          Biological Chemistry II (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2019, To Mar. 2020
          Bioligical Chemistry 2 (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2019, To Mar. 2020
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2020, To Mar. 2021
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Laboratory Practice in Basic Physiological Chemistry
          Spring, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Laboratory Practice in Basic Physiological Chemistry
          Fall, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Research in Basic Physiological Chemistry
          Spring, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Research in Basic Physiological Chemistry
          Fall, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar in Basic Physiological Chemistry
          Spring, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar in Basic Physiological Chemistry
          Fall, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Basic Laboratory Techniques in Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Basic Laboratory Techniques in Biological Chemistry
          Fall, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Biological Chemistry II (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2020, To Mar. 2021
          Biological Chemistry 2 (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2020, To Mar. 2021
          Basic Laboratory Techniques in Pharmaceutical Sciences
          Spring, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Pharmaceutical Laboratory IV : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2020, To Mar. 2021
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2021, To Mar. 2022
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Laboratory Practice in Basic Physiological Chemistry
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Laboratory Practice in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Research in Basic Physiological Chemistry
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Research in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar in Basic Physiological Chemistry
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar in Basic Physiological Chemistry
          Year-long, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Basic Laboratory Techniques in Biological Chemistry
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Basic Laboratory Techniques in Biological Chemistry
          Fall, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Biological Chemistry II (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2021, To Mar. 2022
          Biological Chemistry 2 (Energy Metabolism)
          Spring, 薬学部
        • From Apr. 2021, To Mar. 2022
          Basic Laboratory Techniques in Pharmaceutical Sciences
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Pharmaceutical Laboratory IV : Biochemistry and Microbiology
          Fall, 薬学部
        • From Apr. 2021, To Mar. 2022
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        list
          Last Updated :2022/05/14

          Administration

          School management (title, position)

          • From 01 Apr. 2017, To 31 Mar. 2019
            環境管理専門委員会無機廃液管理小委員会委員
          • From 01 May 2016, To 31 Mar. 2019
            国際高等教育院 企画評価専門委員会 初修外国語部会 委員
          • From 01 Apr. 2017
            環境安全保全機構環境管理専門委員会委員(無機)
          • From 01 Apr. 2019, To 31 Mar. 2020
            国際高等教育院 企画評価専門委員会 初修外国語部会 委員
          • From 01 Apr. 2020, To 31 Mar. 2021
            国際高等教育院 企画評価専門委員会 初修外国語部会 委員
          • From 01 Apr. 2021, To 31 Mar. 2022
            国際高等教育院 企画評価専門委員会 初修外国語部会 委員

          Faculty management (title, position)

          • From 01 Apr. 2011, To 31 Mar. 2012
            情報システム委員会 委員
          • From 01 Apr. 2014, To 31 Mar. 2022
            図書委員会 委員
          • From 01 Apr. 2015, To 31 Mar. 2020
            建物・設備・機器管理運営委員会 委員
          • From 01 Apr. 2016, To 31 Mar. 2018
            学生委員
          • From 01 Apr. 2016, To 31 Mar. 2022
            教務委員会 委員
          • From 01 Apr. 2019, To 31 Mar. 2022
            人権委員会 委員
          • From 01 Apr. 2019, To 31 Mar. 2022
            ハラスメント相談窓口
          list
            Last Updated :2022/05/14

            Academic, Social Contribution

            Social Contribution

            • 女子中高生のためのサイエンスカフェ
              Lecturer
              日本学術振興会科学研究費補助金新学術領域「動的秩序と機能」領域, From 11 Mar. 2017

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