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Nakashima, Yasuhiro

KYOTO UNIVERSITY HOSPITAL Program-Specific Senior Lecturer/Program-Specific Junior Associate Professor

Nakashima, Yasuhiro
list
    Last Updated :2022/06/30

    Basic Information

    Academic Degree

    • 博士(医学)(京都大学)

    Research History

    • Kyoto University

    Profile

    • Profile

      My research field is the cardiovascular basic science. From 2011 to 2014, I worked as a postdoc to research cardiac stem cell and developmental biology in UCLA.

    Language of Instruction

    • English

    ID,URL

    researchmap URL

    list
      Last Updated :2022/06/30

      Research

      Research Topics, Overview of the research

      • Research Topics

        Investigation of the regulatory mechanism of differentiation and proliferation of cardiovascular cells
      • Overview of the research

        The mechanism in the differentiation and proliferation of cardiovascular cells still remains unclear. I am aiming to elucidate the molecular mechanisms underlying the cardiovascular diseases on the basis of my knowledge in the developmental and stem cell biology.

      Research Interests

      • Genomic Medicine
      • Molecular Biology
      • Basic Medical Science
      • Cardiovascular Medicine

      Research Areas

      • Life sciences, Cardiology

      Papers

      • Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo.
        Nakazeki F; Nishiga M; Horie T; Nishi H; Nakashima Y; Baba O; Kuwabara Y; Nishino T; Nakao T; Ide Y; Koyama S; Kimura M; Tsuji S; Sowa N; Yoshida S; Conway SJ; Yanagita M; Kimura T; Ono K
        Sci Rep., Jun. 2018, Peer-reviewed
      • MicroRNA-33 regulates the population of peripheral inflammatory Ly6Chigh monocytes through dual pathways.
        Baba O; Horie T; Nakao T; Hakuno D; Nakashima Y; Nishi H; Kuwabara Y; Nishiga M; Nishino T; Ide Y; Nakazeki F; Koyama S; Kimura M; Hanada R; Kawahara M; Kimura T; Ono K
        Mol Cell Biol., Apr. 2018, Peer-reviewed
      • Dynamic changes of serum microRNA-122-5p through therapeutic courses indicates amelioration of acute liver injury accompanied by acute cardiac decompensation.
        Koyama S; Kuragaichi T; Sato Y; Kuwabara Y; Usami S; Horie T; Baba O; Hakuno D; Nakashima Y; Nishino T; Nishiga M; Nakao T; Arai H; Kimura T; Ono K
        ESC Heart Failure, May 2017, Peer-reviewed
      • MicroRNA-33 Controls Adaptive Fibrotic Response in the Remodeling Heart by Preserving Lipid Raft Cholesterol
        Masataka Nishiga; Takahiro Horie; Yasuhide Kuwabara; Kazuya Nagao; Osamu Baba; Tetsushi Nakao; Tomohiro Nishino; Daihiko Hakuno; Yasuhiro Nakashima; Hitoo Nishi; Fumiko Nakazeki; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Ritsuko Hanada; Tomoyuki Nakamura; Tsukasa Inada; Koji Hasegawa; Simon J. Conway; Toru Kita; Takeshi Kimura; Koh Ono
        CIRCULATION RESEARCH, Mar. 2017, Peer-reviewed
      • Prevention of neointimal formation using miRNA-126-containing nanoparticle-conjugated stents in a rabbit model
        Masayasu Izuhara; Yasuhide Kuwabara; Naritatsu Saito; Erika Yamamoto; Daihiko Hakuno; Yasuhiro Nakashima; Takahiro Horie; Osamu Baba; Masataka Nishiga; Tetsushi Nakao; Tomohiro Nishino; Fumiko Nakazeki; Yuya Ide; Masahiro Kimura; Takeshi Kimura; Koh Ono
        PLOS ONE, Mar. 2017, Peer-reviewed
      • Expression Patterns of miRNA-423-5p in the Serum and Pericardial Fluid in Patients Undergoing Cardiac Surgery
        Shoichi Miyamoto; Shunsuke Usami; Yasuhide Kuwabara; Takahiro Horie; Osamu Baba; Daihiko Hakuno; Yasuhiro Nakashima; Masataka Nishiga; Masayasu Izuhara; Tetsushi Nakao; Tomohiro Nishino; Yuya Ide; Fumiko Nakazeki; Jun Wang; Koji Ueyama; Takeshi Kimura; Koh Ono
        PLOS ONE, Nov. 2015, Peer-reviewed
      • Heterozygous deletion of sarcolipin maintains normal cardiac function
        Daisuke Shimura; Yoichiro Kusakari; Tetsuo Sasano; Yasuhiro Nakashima; Gaku Nakai; Qibin Jiao; Meihua Jin; Tomohiro Yokota; Yoshihiro Ishikawa; Atsushi Nakano; Nobuhito Goda; Susumu Minamisawa
        AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, Jan. 2015, Peer-reviewed
      • Nkx2-5 Suppresses the Proliferation of Atrial Myocytes and Conduction System
        Yasuhiro Nakashima; Diana A. Yanez; Marlin Touma; Haruko Nakano; Artur Jaroszewicz; Maria C. Jordan; Matteo Pellegrini; Kenneth P. Roos; Atsushi Nakano
        CIRCULATION RESEARCH, Mar. 2014, Peer-reviewed
      • Rigid microenvironments promote cardiac differentiation of mouse and human embryonic stem cells
        Armin Arshi; Yasuhiro Nakashima; Haruko Nakano; Sarayoot Eaimkhong; Denis Evseenko; Jason Reed; Adam Z. Stieg; James K. Gimzewski; Atsushi Nakano
        SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS, Apr. 2013, Peer-reviewed
      • Haemogenic endocardium contributes to transient definitive haematopoiesis
        Haruko Nakano; Xiaoqian Liu; Armin Arshi; Yasuhiro Nakashima; Ben van Handel; Rajkumar Sasidharan; Andrew W. Harmon; Jae-Ho Shin; Robert J. Schwartz; Simon J. Conway; Richard P. Harvey; Mohammad Pashmforoush; Hanna K. A. Mikkola; Atsushi Nakano
        NATURE COMMUNICATIONS, Mar. 2013, Peer-reviewed
      • Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway
        Takahiro Horie; Koh Ono; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Shin Watanabe; Yasuhide Kuwabara; Yasuhiro Nakashima; Rieko Takanabe-Mori; Eiichiro Nishi; Koji Hasegawa; Toru Kita; Takeshi Kimura
        CARDIOVASCULAR RESEARCH, Sep. 2010, Peer-reviewed
      • The search for Nkx2-5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2-5 gene targeting
        Yasuhiro Nakashima; Koh Ono; Yoshinori Yoshida; Yoji Kojima; Toru Kita; Makoto Tanaka; Takeshi Kimura
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Dec. 2009, Peer-reviewed
      • Progranulin expression in advanced human atherosclerotic plaque
        Yoji Kojima; Koh Ono; Katsumi Inoue; Yasushi Takagi; Ken-ichiro Kikuta; Masaki Nishimura; Yoshinori Yoshida; Yasuhiro Nakashima; Hironobu Matsumae; Yutaka Furukawa; Nobuhiro Mikuni; Masakiyo Nobuyoshi; Takeshi Kimura; Toru Kita; Makoto Tanaka
        ATHEROSCLEROSIS, Sep. 2009, Peer-reviewed
      • CCN1 knockdown suppresses neointimal hyperplasia in a rat artery balloon injury model
        Hironobu Matsumae; Yoshinori Yoshida; Koh Ono; Kiyonori Togi; Katsumi Inoue; Yutaka Furukawa; Yasuhiro Nakashima; Yoji Kojima; Masakiyo Nobuyoshi; Toru Kita; Makoto Tanaka
        ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, Jun. 2008, Peer-reviewed
      • CCN1 protects cardiac myocytes from oxidative stress via beta 1 integrin-Akt pathway
        Yoshinori Yoshida; Kiyonori Togi; Hironobu Matsumae; Yasuhiro Nakashima; Yoji Kojima; Hiromi Yamamoto; Koh Ono; Tomoyuki Nakamura; Toru Kita; Makoto Tanaka
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2007, Peer-reviewed
      • A high glycolytic flux supports the proliferative potential of murine embryonic stem cells
        Hiroshi Kondoh; Matilde E. Lleonart; Yasuhiro Nakashima; Masayuki Yokode; Makoto Tanaka; David Bernard; Jesus Gil; David Beach
        ANTIOXIDANTS & REDOX SIGNALING, Mar. 2007, Peer-reviewed
      • Endothelin-1 activates Homer 1a expression via mitogen-activated protein kinase in cardiac myocytes
        T Kawamoto; K Togi; R Yamauchi; Y Yoshida; Y Nakashima; T Kita; M Tanaka
        INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Jul. 2006, Peer-reviewed
      • Essential role of Hand2 in interventricular septum formation and trabeculation during cardiac development
        K Togi; Y Yoshida; H Matsumae; Y Nakashima; T Kita; M Tanaka
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2006, Peer-reviewed
      • A Long Dialysis Period has a Strong Impact on Restenosis after Percutaneous Coronary Intervention (PCI) in Chronic Hemodialysis Patients
        NAKASHIMA Yasuhiro; KATAOKA Kazuaki; TANIGUCHI Ryoji; MIYAMOTO Tadashi; HOSHINO(NAGAI) Kozo; MAKIYAMA Takeru; KATO Takao; HORIE Takahiro; NAGAO Kazuya; TAKATSU Yoshiki
        Jpn J Interv Cardiol, 10 Feb. 2004
      • Overview of the 84th Annual Scientific Meeting of the Japanese Circulation Society - Change Practice!
        Koh Ono; Satoshi Shizuta; Erika Yamamoto; Naritatsu Saito; Neiko Ozasa; Takao Kato; Eri Kato; Takahiro Horie; Junichi Tazaki; Hiroki Shiomi; Shin Watanabe; Hirotoshi Watanabe; Yugo Yamashita; Yusuke Yoshikawa; Hideyuki Kinoshita; Takeru Makiyama; Yoshinori Yoshida; Noboru Ashida; Yasuaki Nakagawa; Yasuhiro Nakashima; Osamu Baba; Hirohiko Kohjitani; Masahiro Kimura; Hideaki Inazumi; Takashi Yoshizawa; Akihiro Komasa; Takeshi Kimura
        Circulation journal : official journal of the Japanese Circulation Society, 25 Feb. 2021
      • Lionheart LincRNA alleviates cardiac systolic dysfunction under pressure overload.
        Yasuhide Kuwabara; Shuhei Tsuji; Masataka Nishiga; Masayasu Izuhara; Shinji Ito; Kazuya Nagao; Takahiro Horie; Shin Watanabe; Satoshi Koyama; Hisanori Kiryu; Yasuhiro Nakashima; Osamu Baba; Tetsushi Nakao; Tomohiro Nishino; Naoya Sowa; Yui Miyasaka; Takeshi Hatani; Yuya Ide; Fumiko Nakazeki; Masahiro Kimura; Yoshinori Yoshida; Tsukasa Inada; Takeshi Kimura; Koh Ono
        Communications biology, 13 Aug. 2020
      • Homeobox A4 suppresses vascular remodeling by repressing YAP/TEAD transcriptional activity
        Masahiro Kimura; Takahiro Horie; Osamu Baba; Yuya Ide; Shuhei Tsuji; Randolph Ruiz Rodriguez; Toshimitsu Watanabe; Tomohiro Yamasaki; Chiharu Otani; Sijia Xu; Yui Miyasaka; Yasuhiro Nakashima; Takeshi Kimura; Koh Ono
        EMBO Rep (2020) e48389 Published as Early View, Mar. 2020, Peer-reviewed
      • Cardioprotective Effects of VCP Modulator KUS121 in Murine and Porcine Models of Myocardial Infarction.
        Yuya Ide; Takahiro Horie; Naritatsu Saito; Shin Watanabe; Chiharu Otani; Yui Miyasaka; Yasuhide Kuwabara; Tomohiro Nishino; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Fumiko Nakazeki; Satoshi Koyama; Masahiro Kimura; Shuhei Tsuji; Randolph Ruiz Rodriguez; Sijia Xu; Tomohiro Yamasaki; Toshimitsu Watanabe; Masamichi Yamamoto; Motoko Yanagita; Takeshi Kimura; Akira Kakizuka; Koh Ono
        JACC. Basic to translational science, Oct. 2019, Peer-reviewed
      • Identification of Differential Roles of MicroRNA-33a and -33b During Atherosclerosis Progression With Genetically Modified Mice.
        Koyama S; Horie T; Nishino T; Baba O; Sowa N; Miyasaka Y; Kuwabara Y; Nakao T; Nishiga M; Nishi H; Nakashima Y; Nakazeki F; Ide Y; Kimura M; Tsuji S; Ruiz Rodriguez R; Xu S; Yamasaki T; Otani C; Watanabe T; Nakamura T; Hasegawa K; Kimura T; Ono K
        Journal of the American Heart Association, Jul. 2019, Peer-reviewed
      • is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.
        Fumiko Nakazeki; Itaru Tsuge; Takahiro Horie; Keiko Imamura; Kayoko Tsukita; Akitsu Hotta; Osamu Baba; Yasuhide Kuwabara; Tomohiro Nishino; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Shuhei Tsuji; Motoko Naitoh; Shigehiko Suzuki; Yuishin Izumi; Toshitaka Kawarai; Ryuji Kaji; Takeshi Kimura; Haruhisa Inoue; Koh Ono
        Clinical Science, 22 Feb. 2019, Peer-reviewed
      • MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.
        Nakazeki F; Tsuge I; Horie T; Imamura K; Tsukita K; Hotta A; Baba O; Kuwabara Y; Nishino T; Nakao T; Nishiga M; Nishi H; Nakashima Y; Ide Y; Koyama S; Kimura M; Tsuji S; Naitoh M; Suzuki S; Izumi Y; Kawarai T; Kaji R; Kimura T; Inoue H; Ono K
        Clinical science (London, England : 1979), Feb. 2019, Peer-reviewed
      • Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction.
        Hakuno D; Kimura M; Ito S; Satoh J; Nakashima Y; Horie T; Kuwabara Y; Nishiga M; Ide Y; Baba O; Nishi H; Nakao T; Nishino T; Nakazeki F; Koyama S; Hanada R; Randolph RR; Endo J; Kimura T; Ono K
        Scientific reports, Nov. 2018, Peer-reviewed
      • SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo.
        Nishino T; Horie T; Baba O; Sowa N; Hanada R; Kuwabara Y; Nakao T; Nishiga M; Nishi H; Nakashima Y; Nakazeki F; Ide Y; Koyama S; Kimura M; Nagata M; Yoshida K; Takagi Y; Nakamura T; Hasegawa K; Miyamoto S; Kimura T; Ono K
        Arteriosclerosis, thrombosis, and vascular biology, Oct. 2018, Peer-reviewed
      • 開心術をうけた心血管患者血清と心嚢水におけるマイクロRNA423‐5pの発現
        宇佐美俊輔; 宮本昌一; 桑原康秀; 堀江貴裕; 馬場理; 伯野大彦; 中島康弘; 西賀雅隆; 出原正康; 中尾哲史; 西野共達; 井手裕也; 中関典子; 木村昌弘; 花田律子; 植山浩二; 木村剛; 尾野亘
        血管, 31 Jan. 2016
      • Serum HDL Cholesterol Decreases in Microrna-33b Knock-in Mice for an Intron of Sterol Regulatory Element-binding Factor 1 (Srebf1)
        Hone Takahiro; Nishino Tomohiro; Baba Osamu; Kuwabara Yasuhide; Nakao Tetsushi; Nishiga Masataka; Usami Shunsuke; Izuhara Masayasu; Nakazeki Fumiko; Ide Yuya; Koyama Satoshi; Sowa Naoya; Nakashima Yasuhiro; Hakuno Daihiko; Kimura Takeshi; Ono Koh
        CIRCULATION, 10 Nov. 2015, Peer-reviewed
      • 僧帽弁逆流の成因解明にストレインエコーが有用であった心サルコイドーシスの1症例
        米田智也; 木下秀之; 相澤卓範; 岡林真梨恵; 中島康弘; 山田千夏; 今井逸雄; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 一山智; 木村剛
        日本循環器学会近畿地方会(Web), 2015
      • A common metabolic profile shared between murine ES cells and primary cells bypassing senescence.
        Hiroshi Kondoh; Matilde E. Lleonart; Yasuhiro Nakashima; Takeshi Maruyama; Masayuki Yokode; Makoto Tanaka; David Bernard; Jesus Gil
        Medical Hypotheses and Research 2008.4.29-36, 2008, Peer-reviewed
      • A Long Dialysis Period has a Strong Impact on Restenosis after Percutaneous Coronary Intervention (PCI) in Chronic Hemodialysis Patients
        Y. Nakashima; K. Kataoka; R. Taniguchi; T. Miyamoto; K. Hoshino-Nagai; T. Makiyama; T. Kato; T. Horie; K. Nagao; Y. Takatsu
        Japanese Journal of Interventional Cardiology, 2004, Peer-reviewed
      • Vessel Size, Not Stent Length, Is the Most Important Predictor of Restenosis after NIR Stent Implantation
        T. Miyamoto; K. Nagai; Y. Sato; T. Makiyama; K. Nagao; Y. Nakashima; T. Kato; T. Horie; R. Taniguchi; T. Yamada; K. Kataoka; Y. Takatsu
        Japanese Journal of Interventional Cardiology, 2004, Peer-reviewed

      Misc.

      • OE-392 Progranulin Expression in Advanced Human Atherosclerotic Plaque(OE66,Atherosclerosis (Clinical/Pathophysiology) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
        Kojima Yoji; Ono Koh; Inoue Katsumi; Yoshida Yoshinori; Nakashima Yasuhiro; Matsumae Hironobu; Furukawa Yutaka; Nobuyoshi Masakiyo; Kimura Takeshi; Kita Toru; Tanaka Makoto
        Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2009
      • Nkx2-5 suppresses the formation of the conduction cells and the proliferation of atrial cardiomyocytes
        Yasuhiro Nakashima
        American Heart Association (AHA) Scientific Sessions, 18 Nov. 2013, Invited
      • Notch Signaling Induces Endocardial Hematopoiesis and Cushion Formation Downstream of Nkx2-5
        Yasuhiro Nakashima
        Basic Cardiovascular Sciences (BCVS), 22 Jul. 2013
      • Nkx2-5 Suppresses the Proliferation of the Atrial Cardiomyocytes and Formation of the Conduction Cells during Cardiac Development.
        Yasuhiro Nakashima
        Basic Cardiovascular Sciences (BCVS), 22 Jul. 2013
      • Nkx2-5 suppresses the formation of the conduction cells and the proliferation of atrial cardiomyocytes
        Yasuhiro Nakashima
        International Society for Stem Cell Research, 01 May 2013
      • The investigation of the role of Nkx2-5 in cardiomyocyte differentiation using Nkx2-5 null ES cell
        Yasuhiro Nakashima
        Keystone Symposia, 2010
      • The Identification of the Nkx2-5-regulated Genes Using Purified ES Cell-derived Cardiomyocytes
        Yasuhiro Nakashima; Koh Ono; Yoshinori Yoshida; Yoji Kojima; Toru Kita; Takeshi Kimura
        CIRCULATION, Nov. 2009
      • ES細胞増殖に必須な代謝特性としての解糖系代謝亢進
        KONDO HIROSHI; NAKASHIMA YASUHIRO; MARUYAMA TAKESHI; TANAKA MAKOTO; YOKODE MASAYUKI
        再生医療, 01 May 2008
      • Establishment of a new method for the investigation of cardiac transcription factor
        Yasuhiro Nakashima; Yoshinori Yoshida; Yohji Kojima; Makoto Tanaka; Toru Kita
        JOURNAL OF CARDIAC FAILURE, Sep. 2008
      • ペースメーカー不全を来ししきい値の急上昇で発見されたアミロイドーシスの一例
        KATO TAKAO; MIYAMOTO TADASHI; NAGAO KAZUYA; HORIE TAKAHIRO; NAKAJIMA YASUHIRO; KATAOKA KAZUAKI; TAKATSU YOSHIKI
        Circ J, 20 Apr. 2004
      • 両側内胸動脈にも解離の及んだ冠動脈自然解離の一例
        NAGAO KAZUYA; TAKATSU YOSHIKI; MIYAMOTO TADASHI; KATAOKA KAZUAKI; NAKAJIMA YASUHIRO; KATO TAKAO; HORIE TAKAHIRO; NOMOTO SHIN'ICHI; KIN KEN'ICHI
        Circ J, 20 Apr. 2004
      • Vessel Size, Not Stent Length, Is The Most Important Predictor of Restenosis after NIR Stent Implantation
        MIYAMOTO Tadashi; NAGAI Kozo; SATO Yukihito; MAKIYAMA Takeru; NAGAO Kazuya; NAKASHIMA Yashiro; KATO Takao; HORIE Takahiro; TANIGUCHI Ryoji; YAMADA Tasuku; KATAOKA Kazuaki; TAKATSU Yoshiki
        Jpn J Interv Cardiol, 10 Feb. 2004
      • 第一回 臨床心不全フォーラム カルペリチドが有用であった大動脈弁狭窄症に冠動脈疾患を合併した心不全の1例
        HORIE TAKAHIRO; KATAOKA KAZUAKI; NAGAO KAZUYA; KATO TAKAO; NAKASHIMA YASUHIRO; MIYAMOTO TADASHI; TAKATSU YOSHIKI
        循環器科, 28 Jan. 2004
      • しきい値の急上昇をきたしペースメーカー不全をきたして発見されたアミロイドーシスの1例
        KATO TAKAO; MIYAMOTO TADASHI; NAGAO KAZUYA; HORIE TAKAHIRO; NAKAJIMA YASUHIRO; KATAOKA KAZUAKI; TAKATSU YOSHIKI
        血管と心研究会誌, Dec. 2003
      • 孤立,腫りゅう形成型の心転移を認めた転移性子宮筋腫の一例
        HORIE TAKAHIRO; MIYAMOTO TADASHI; KATAOKA KAZUAKI; NAKASHIMA YASUHIRO; KATO TAKAO; NAGAO KAZUYA; TAKATSU YOSHIKI
        診療と新薬, 28 Jan. 2003
      • Radiusステントの初期および慢性期成績の検討
        NAGAI KOZO; MIYAMOTO TADASHI; RI SHUNKYO; MAKIYAMA TAKESHI; NAKAJIMA YASUHIRO; HORIE TAKAHIRO; KATO TAKAO; TAKATSU YOSHIKI
        Jpn J Interv Cardiol, 10 Jun. 2002
      • 経皮的血管縫合器(Prostar XL/Closer)によるPCI後の縫合止血の成績とその検討
        NAKASHIMA YASUHIRO; NAGAI KOZO; MAKIYAMA TAKESHI; KATO TAKAO; HORIE TAKAHIRO; RI SHUNKYO; MIYAMOTO TADASHI; TAKATSU YOSHIKI
        Jpn J Interv Cardiol, 10 Jun. 2002
      • 慢性腎不全患者の心疾患 慢性腎不全透析患者における冠動脈造影所見および治療成績の検討
        NAKAJIMA YASUHIRO; MIYAMOTO CHUJI; TANIGUCHI RYOJI; NAGAI KOZO; MAKIYAMA TAKESHI; KATO TAKAO; HORIE TAKAHIRO; SATO YUKITO; TAKATSU YOSHIKI
        診療と新薬, 28 Feb. 2002
      • Measurement of serum concentrations of cardiac troponin. T in the management and treatment of cardiac disorders in patients with hypereosinophilic syndrome-A case report
        Taniguchi Ryoji; Sato Yukihito; Nagai Kozo; Makiyama Takeru; Okada Hideshi; Nakashima Yasuhiro; Matsumori Akira; Takatsu Yoshiki
        Shinzo, 2002
      • 血中心筋トロポニンTの心アミロイドーシスにおける測定意義
        MAKIYAMA TAKESHI; SATO YUKIHITO; MIYAMOTO TADASHI; TANIGUCHI RYOJI; NAGAI KOZO; OKADA EIJI; NAKAJIMA YASUHIRO; TAKATSU YOSHIKI
        血管と心研究会誌, Dec. 2001
      • 肥大型心筋症 肥大型心筋症における微少心筋障害の検出 心筋トロポニンTを用いて
        NAGAI KOZO; SATO YUKIHITO; MIYAMOTO TADASHI; TANIGUCHI RYOJI; MAKIYAMA TAKESHI; OKADA HIDESHI; NAKASHIMA YASUHIRO; TAKATSU YOSHIKI
        診療と新薬, 28 Sep. 2001
      • Stent in‐stentの初期および慢性期成績
        MAKIYAMA TAKERU; SATO YUKIHITO; TANIGUCHI RYOJI; NAGAI KOZO; OKADA EIJI; NAKAJIMA YASUHIRO; TAKATSU YOSHIKI
        Jpn J Interv Cardiol, 10 Jun. 2001
      • Nir stentの初期および慢性期成績ならびにMultilink stentとの比較
        NAGAI KOZO; SATO YUKIHITO; TANIGUCHI RYOJI; MAKIYAMA TAKESHI; OKADA EIJI; NAKAJIMA YASUHIRO; WASHIZU YOSHIKI
        Jpn J Interv Cardiol, 10 Jun. 2001
      • Percutaneous pericardial biopsy for the diagnosis of pericardial effusion : Case reports
        Takeru Makiyama; Yukihito Sato; Ryoji Taniguchi; Kozo Nagai; Hideshi Okada; Yasuhiro Nakashima; Shigetake Sasayama; Akira Matumori; Yoshiki Takatsu
        Respiration and Circulation, Mar. 2001
      • 経皮的心膜生検が診断に有用であった一例 (兵庫県立尼崎病院S,兵庫県立東洋医学研究所S)
        MAKIYAMA TAKESHI; SATO YUKITO; TANIGUCHI RYOJI; NAGAI KOZO; OKADA HIDESHI; NAKAJIMA YASUHIRO; TAKATSU YOSHIKI
        兵庫県立尼崎病院年報, 10 Mar. 2001
      • MicroRNA-33 Maintains Cellular Cholesterol Content in Fibroblasts and Fibrotic Response in Heart
        Masataka Nishiga; Takahiro Horie; Yasuhide Kuwabara; Osamu Baba; Tetsushi Nakao; Tomohiro Nishino; Daihiko Hakuno; Yasuhiro Nakashima; Kazuya Nagao; Koji Hasegawa; Toru Kita; Takeshi Kimura; Koh Ono
        CIRCULATION, Nov. 2016
      • 肺動脈性肺高血圧症に対する肺移植術後急性期における左室および右室機能の評価
        米田智也; 木下秀之; 木下秀之; 中島康弘; 中島康弘; 本山秀樹; 土屋恭子; 青山晃博; 陳豊史; 中川靖章; 柳澤洋; 牧山武; 静田聡; 桑原宏一郎; 木村剛; 伊達洋至; 一山智
        日本心臓病学会学術集会(Web), Sep. 2016
      • 肺動脈性肺高血圧症における肺移植術後急性期の左室機能の検討
        米田智也; 木下秀之; 中島康弘; 本山秀樹; 土屋恭子; 青山晃博; 陳豊史; 柳沢洋; 山田千夏; 今井逸雄; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 伊達洋至; 一山智; 木村剛
        日本循環器学会近畿地方会(Web), 2015
      • Rigid Microenvironments Promote Cardiac Differentiation Of Mouse And Human Embryonic Stem Cells
        Armin Arshi; Yasuhiro Nakashima; Haruko Nakano; Sarayoot Eaimkhong; Denis Evseenko; Jason Reed; Adam Z. Stieg; James K. Gimzewski; Atsushi Nakano
        CIRCULATION RESEARCH, Aug. 2013
      • Rigid Two-Dimensional Microenvironments Promote Cardiac Differentiation
        Armin Arshi; Yasuhiro Nakashima; Haruko Nakano; Sarayoot Eaimkhong; Adam Z. Stieg; James K. Gimzewski; Atsushi Nakano
        CIRCULATION, Nov. 2012
      • MiR-146a-induced Inhibition of Neuregulin1-ErbB4 Pathway may be Involved in Deterioration of Cardiotoxicity under Concurrent Chemotherapy with Doxorubicin and Trastuzumab.
        Takahiro Horie; Koh Ono; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Shin Watanabe; Yasuhide Kuwabara; Yasuhiro Nakashima; Rieko Takanabe-Mori; Eiichiro Nishi; Koji Hasegawa; Toru Kita; Takeshi Kimura
        CIRCULATION, Nov. 2010
      • Microrna-27a Regulates Beta-Myosin Heavy Chain Gene Expression by Targeting Thyroid Hormone Receptor Beta 1 in Neonatal Rat Ventricular Myocytes
        Hitoo Nishi; Koh Ono; Takahiro Horie; Minao Kinoshita; Shin Watanabe; Yasuhide Kuwabara; Osamu Baba; Yasuhiro Nakashima; Kazuya Nagao; Rieko Takanabe-Mori; Koji Hasegawa; Toru Kita; Takeshi Kimura
        CIRCULATION, Nov. 2010
      • MicroRNA-1 and MicroRNA-133a are Useful as Early Diagnostic Biomarkers in Patients with Acute Coronary Syndrome
        Yasuhide Kuwabara; Koh Ono; Takahiro Horie; Hitoo Nishi; Minako Kinoshita; Shin Watanabe; Yasuhiro Nakashima; Kazuya Nagao; Yoji Kojima; Toru Kita; Takeshi Kimura
        CIRCULATION, Nov. 2010
      • Progranulin is Expressed in the Human Atherosclerotic Plaque and Reduces IL-8 Secretion from Smooth Muscle Cells, Endothelial Cells, And Macrophages
        KOJIMA Yoji; ONO Koh; INOUE Katsumi; YOSHIDA Yoshinori; NAKASHIMA Yasuhiro; NOBUYOSHI Masakiyo; KITA Toru; KIMURA Takeshi; TANAKA Makoto
        Circ J, 01 Mar. 2010, Peer-reviewed
      • PROGRANULIN IN ADVANCED HUMAN ATHEROSCLEROTIC PLAQUE
        Yoji Kojima; Koh Ono; Katsumi Inoue; Yasushi Takagi; Ken-Ichiro Kikuta; Masaki Nishimura; Yoshinori Yoshida; Yasuhiro Nakashima; Hironobu Matsumae; Yutaka Furukawa; Nobuhiro Mikuni; Masakiyo Nobuyoshi; Takeshi Kimura; Toru Kita; Makoto Tanaka
        JOURNAL OF VASCULAR RESEARCH, 2009
      • 心アミロイドーシスにおける血中トロポニンTの測定
        加藤貴雄; 佐藤幸人; 宮本忠司; 松岡龍彦; 長央和也; 堀江貴裕; 中島康弘; 片岡一明; 鷹津良樹
        第8回日本心不全学会学術集会, Oct. 2004, Peer-reviewed
      • Radiusステント留置時の後拡張に関する検討
        片岡 一明; 永井 康三; 李 俊峡; 長央 和也; 加藤 貴雄; 堀江 貴裕; 中島 康弘; 牧山 武; 宮本 忠司; 鷹津 良樹
        Journal of Cardiology, Aug. 2003
      • ステント長と血管径が再狭窄にあたえる影響 冠動脈用ロングステントにおける検討
        永井 康三; 佐藤 幸人; 宮本 忠司; 山田 亮; 谷口 良司; 牧山 武; 中島 康弘; 李 俊侠; 松森 昭; 鷹津 良樹
        Journal of Cardiology, Aug. 2002
      • 肥大型心筋症における微少心筋障害の検出 心筋トロポニンTを用いて
        永井 康三; 佐藤 幸人; 宮本 忠司; 谷口 良司; 牧山 武; 岡田 英志; 中島 康弘; 鷹津 良樹
        診療と新薬, Feb. 2002

      Presentations

      • 発生期心房および刺激伝導系における心筋細胞増殖制御
        中島 康弘
        第79回日本循環器学会総会学術集会, 24 Apr. 2015, Invited
      • 発生期心房および刺激伝導系における心筋細胞増殖制御
        中島 康弘
        第21回動脈硬化若手研究会, 25 Oct. 2014, Invited
      • Nkx2-5 Regulates the Proliferation of Atrial Myocytes and Conduction System
        Yasuhiro Nakashima
        Molecular Cardiovascular Conference II (MCC II), 05 Sep. 2014, Invited

      Books and Other Publications

      • Cardiac Regeneration using ES and iPS Cells
        Yasuhiro Nakashima, Contributor, Cardiac Regeneration Using Isl1-positive Cardiac Progenitor Cells
        CRC Press, Apr. 2013, Not refereed

      Awards

      • 01 Apr. 2009
        Kyoto University, 京都大学グローバルCOEアソシエイトフェローシップ
      • 01 Jul. 2010
        Japan Society for the Promotion of Science (JSPS), 海外インターンシップ
      • 01 Apr. 2012
        Japanese Circulation Society (JCS), 日本循環器学会 留学支援基金
      • 01 Apr. 2013
        Uehara Memorial Foundation, 上原記念生命科学財団 リサーチフェローシップ
      • 29 May 2013
        UCLA Broad Stem Cell Research Center (BSCRC), BSCRC Travel Award
      • 23 Jul. 2013
        American Heart Association (AHA), Best of AHA Specialty Conferences Poster Sessions

      External funds: Kakenhi

      • 心血管疾患関連遺伝子CSRPのヒト遺伝子変異による分子機能異常の解明
        Grant-in-Aid for Scientific Research (C)
        Basic Section 53020:Cardiology-related
        Kyoto University
        中島 康弘
        From 01 Apr. 2019, To 31 Mar. 2022, Granted
        ゲノム医学;遺伝子変異;分子生物学;動脈硬化
      • The investigation of the role of early-postnatal expressing genes in cardiomyocyte proliferation
        Grant-in-Aid for Scientific Research (C)
        Kyoto University
        YASUHIRO NAKASHIMA
        From 01 Apr. 2016, To 31 Mar. 2019, Project Closed
        心筋分化;細胞増殖;心発生
      • Investigation of the regulatory mechanism of perinatal cardiomyocyte maturation
        Grant-in-Aid for Research Activity Start-up
        Kyoto University
        YASUHIRO NAKASHIMA
        From 29 Aug. 2014, To 31 Mar. 2016, Project Closed
        心筋分化;心発生;細胞増殖;心筋細胞増殖
      • 心筋分化過程における心筋細胞表面マーカーの探索とその機能解析
        Grant-in-Aid for Young Scientists (B)
        Kyoto University
        中島 康弘
        Project Closed
        心筋細胞分化;ES細胞;遺伝子;再生医療
      • In vitro変異体スクリーニングによる遺伝的要因の検討法の確立
        Grant-in-Aid for Scientific Research (C)
        Basic Section 53020:Cardiology-related
        Kyoto University
        中島 康弘
        From 01 Apr. 2022, To 31 Mar. 2025, Adopted

      External funds: others

      • 出生後早期における心筋細胞増殖制御因子の同定
        Banyu Foundation Research Grant 2014
        From 01 Oct. 2014, To 30 Sep. 2016
        中島康弘
      • 成体心筋細胞における心臓転写因子Nkx2-5による増殖抑制機序の検討
        かなえ医薬振興財団 研究助成
        From 01 Jan. 2015, To 31 Dec. 2015
        中島康弘

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