Basic Information

Faculty

• 医学部

Professional Memberships

• Society for Neuroscience
• The Japan Neuroscience Society
• The Physiological Society of Japan

Academic Degree

• M.S.(Kobe University)
• Ph.D.(Kyoto University)

Academic Resume (Graduate Schools)

• Kobe University, Graduate school of Science, Biology, 修了
• Kyoto University, Gradate school of Medicine, Medicine, 修了

Academic Resume (Undergraduate School/Majors)

• Kobe University, Faculty of Science, Biology, 卒業

Research History

• From Jul. 2016, To Oct. 2016

  Graduate School of Medicine Kyoto University, Physiology and Neuroscience, Postdoc researcher
• From Apr. 2012, To Jun. 2016

  National Institute for Physiological Sciences, Department of Developmental Physiology, Postdoc researcher

ID,URL

• J-Global ID

  201601015597852003

Website(s) (URL(s))

• http://nscinbiol.med.kyoto-u.ac.jp/people/4/
• https://scrapbox.io/lattice-open/

researchmap URL

• https://researchmap.jp/KASAI_Masatoshi

Research

Research Topics, Overview of the research

• Research Topics

  Neural mechanisms of visual processing and visuomotor transformation in the superior colliculus

• Overview of the research

  Superior colliculus (SC) has a key role for neural basis of visuomotor transformation and formation of our attention. Most visual information is processed in the visual cortices and the SC also process visual information in parallel. I am interested in the meaning and neural circuit mechanisms of this subcortical visual processing.

Research Interests

• in vivo electrophysiology
• in vivo Two-photon imaging
• Inferior Colliculus
• Superior Colliculus

Research Areas

• Life sciences, Neuroscience - general

Papers

• Effects of light isoflurane anesthesia on organization of direction and orientation selectivity in the superficial layer of the mouse superior colliculus

  Masatoshi Kasai; Tadashi Isa

  The Journal of Neuroscience, 06 Dec. 2021, Peer-reviewed, Lead author, Corresponding author

  
• Anatomical and electrophysiological analysis of cholinergic inputs from the parabigeminal nucleus to the superficial superior colliculus.

  Kota Tokuoka; Masatoshi Kasai; Kenta Kobayashi; Tadashi Isa

  Journal of neurophysiology, 21 Oct. 2020, Peer-reviewed

  
• Integrative taxonomic approach of trypanosomes in the blood of rodents and soricids in Asian countries, with the description of three new species.

  Mafie E; Saito-Ito A; Kasai M; Hatta M; Rivera PT; Ma XH; Chen ER; Sato H; Takada N

  Parasitology research, Oct. 2018, Peer-reviewed

  
• Imaging population dynamics of surround suppression in the superior colliculus

  Masatoshi Kasai; Tadashi Isa

  EUROPEAN JOURNAL OF NEUROSCIENCE, Oct. 2016, Peer-reviewed, Lead author

  
• In vivo two-photon imaging of dendritic spines in marmoset neocortex

  Osamu Sadakane; Akiya Watakabe; Masanari Ohtsuka; Masafumi Takaji; Tetsuya Sasaki; Masatoshi Kasai; Tadashi Isa; Go Kato; Junichi Nabekura; Hiroaki Mizukami; Keiya Ozawa; Hiroshi Kawasaki; Tetsuo Yamamori

  eNeuro, 2015, Peer-reviewed

  
• Distinct neural firing mechanisms to tonal stimuli offset in the inferior colliculus of mice in vivo

  Masatoshi Kasai; Munenori Ono; Harunori Ohmori

  NEUROSCIENCE RESEARCH, Jul. 2012, Peer-reviewed, Lead author, Corresponding author

  
• Survey of Babesia microti infection in field rodents in Japan: Records of the Kobe-type in new foci and findings of a new type related to the Otsu-type

  Atsuko Saito-Ito; Midori Kasahara; Masatoshi Kasai; Anchalee Dantrakool; Atsuko Kawai; Hiromi Fujita; Yasuhiro Yano; Hiroki Kawabata; Nobuhiro Takada

  MICROBIOLOGY AND IMMUNOLOGY, 2007, Peer-reviewed

  

Presentations

• Population dynamics of visual responses in mouse superior colliculus

  KASAI Masatoshi

  1st CU- KU Symposium and 4th CU-NIPS Symposium “Advances in Neuroscience Research”, 17 Feb. 2020, Invited

  
• Two photon imaging for lateral inhibition of neural ensemble in the superficial layer of the superior colliculus

  Masatoshi Kasai

  Gordon Research Conference Eye Movement, Jul. 2013, Invited

  

Books and Other Publications

• HANDBOOK OF BRAIN MICROCIRCUIT

  Tadashi Isa; Masatoshi Kasai; Richard Veale, Joint work, Chapter 39, The Superior Colliculus

  OXFORD UNIVERSITY PRESS, Jan. 2018

  

External funds: Kakenhi

• Elucidation of the neural and molecular basis of functional recovery in the ventral striatum after spinal cord injury in non-human primates

  Grant-in-Aid for Scientific Research (A)

  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields

  Kyoto University

  尾上 浩隆

  From 01 Apr. 2020, To 31 Mar. 2025, Granted

  脊髄損傷;モチベーション;前脳基底部;ドパミン;アセチルコリン;マカクサル;siRNA;AAV;Tet制御;マカクザル;fMRI;ECoG;Ca2+イメージング;AAVベクター;腹側線条体

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H00573/
• Visual information shared between visual cortex and superior colliculus and their mutual regulation mechanisms

  Grant-in-Aid for Scientific Research (C)

  Basic Section 46030:Function of nervous system-related

  Kyoto University

  Masatoshi KASAI

  From 01 Apr. 2019, To 31 Mar. 2022, Project Closed

  上丘;視覚;方向選択性;方位選択性;２光子顕微鏡;in vivo イメージング;麻酔;イソフルラン;覚醒;視覚野;経シナプス;カルシウムイメージング;光遺伝学;化学遺伝学;抑制性細胞;経シナプス AAV;in vivo;イメージング

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K06940/
• Visual space representation in the mouse superior colliculus

  Grant-in-Aid for Young Scientists (B)

  Kyoto University

  Kasai Masatoshi

  From 01 Apr. 2016, To 31 Mar. 2018, Project Closed

  上丘;2光子顕微鏡;in vivo イメージング;マウス;視覚情報処理;眼球運動;サッカード;カルシウムイメージング;視覚;覚醒下;in vivo;神経科学;生理学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K16654/
• Neuronal population activity of visuo-motor transformation in the superior colliculus

  Grant-in-Aid for Young Scientists (B)

  National Institute for Physiological Sciences

  Masatoshi KASAI

  From 01 Apr. 2014, To 31 Mar. 2016, Project Closed

  上丘;マウス;２光子顕微鏡;in vivo イメージング;側方抑制;視覚;サッカード;眼球運動;in vivo カルシウムイメージング;サッケード;カルシウムイメージング;in vivo

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26750382/
• Saliency detection by the "unconscious" visuo-motor system

  Grant-in-Aid for Scientific Research (S)

  National Institute for Physiological Sciences

  Tadashi ISA

  From 31 May 2010, To 31 Mar. 2015, Project Closed

  意識;上丘;注意;サッケード運動;盲視;２光子レーザー顕微鏡;大規模シミュレーション;霊長類;サリエンシー;視覚;視床枕;頭頂連合野;側方抑制;PET;２光子顕微鏡;マウス;膝状体外視覚系;サル;局所神経回路

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22220006/
• Neural basis of dynamic regulation of direction and orientation map in the superior colliculus

  Grant-in-Aid for Scientific Research (C)

  Basic Section 46030:Function of nervous system-related

  Kyoto University

  笠井 昌俊

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  上丘;方向選択性;方位選択性;２光子顕微鏡;in vivo

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K06471/

Administration

Faculty management (title, position)

• From 01 Apr. 2017, To 31 Mar. 2019

  医学図書館図書連絡委員