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Perron, Amelie
Institute for Chemical Research (ICR) Senior Lecturer/ Junior Associate Professor
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Last Updated :2023/09/22
Basic Information
Affiliated programs (koza)
- Graduate School of Pharmaceutical Sciences, 創発医薬科学専攻 創発医薬科学講座
- Graduate School of Medicine, 医科学専攻 ケミカルバイオロジー, 講師
- Graduate School of Medicine, 医学専攻 ケミカルバイオロジー, 講師
Faculty
Concurrent Affiliation
Academic Degree
ID,URL
J-Global ID
Researcher number
40525862
researchmap URL
list
Last Updated :2023/09/22
Research
Research Topics, Overview of the research
Research Topics
Chemical BiologyOverview of the research
The focus of my current research is on the development of small organic molecules and molecular self-assemblies to control the aggregation of pigments from the retina associated with age-related macular degeneration (AMD).
Research Interests
Research Areas
- Life sciences, Cell biology
- Life sciences, Neuroscience - general
- Nanotechnology/Materials, Chemical biology
Papers
- Chemoproteomic Identification of Blue-Light-Damaged Proteins.Kohei Toh; Kosuke Nishio; Reiko Nakagawa; Syusuke Egoshi; Masahiro Abo; Amelie Perron; Shin-Ichi Sato; Naoki Okumura; Noriko Koizumi; Kosuke Dodo; Mikiko Sodeoka; Motonari UesugiJournal of the American Chemical Society, 28 Oct. 2022, Peer-reviewed
- Magnetic Control of Cells by Chemical Fabrication of Melanin.Kosuke Nishio; Kohei Toh; Amelie Perron; Masato Goto; Masahiro Abo; Yuichi Shimakawa; Motonari UesugiJournal of the American Chemical Society, 21 Sep. 2022, Peer-reviewed
- Discovery of a phase-separating small molecule that selectively sequesters tubulin in cells.Genyir Ado; Naotaka Noda; Hue T. Vu; Amelie Perron; Amarjyoti D. Mahapatra; Karla Pineda Arista; Hideaki Yoshimura; Daniel M. Packwood; Fumiyoshi Ishidate; Shin-ichi Sato; Takeaki Ozawa; Motonari UesugiChemical Science, May 2022, Peer-reviewed
- Fluorescent sensors of membrane potential that are genetically encodedL. Jin; B. J. Baker; Lawrence B. Cohen; H. Mutoh; D. Dimitrov; A. Perron; Y. Iwamoto; E. Y. Isacoff; V. A. Pieribone; T. Hughes; T. Knöpfel; W. AkemannImaging the Brain with Optical Methods, 2010, Peer-reviewed
- Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperoneAmelie Perron; Yoshihiro Nishikawa; Jun Iwata; Hiromi Shimojo; Junichiro Takaya; Kumiko Kobayashi; Itaru Imayoshi; Naasson M. Mbenza; Mihoko Takenoya; Ryoichiro Kageyama; Yuzo Kodama; Motonari UesugiJournal of Biological Chemistry, 2018, Peer-reviewed
- Spinal NTS2 receptor activation reverses signs of neuropathic painPascal Tetreault; Nicolas Beaudet; Amelie Perron; Karine Belleville; Adeline Rene; Florine Cavelier; Jean Martinez; Thomas Stroh; Ashley M. Jacobi; Scott D. Rose; Mark A. Behlke; Philippe SarretFASEB JOURNAL, Sep. 2013, Peer-reviewed
- Imaging neural circuit dynamics with a voltage-sensitive fluorescent proteinWalther Akemann; Hiroki Mutoh; Amelie Perron; Yun Kyung Park; Yuka Iwamoto; Thomas KnoepfelJOURNAL OF NEUROPHYSIOLOGY, Oct. 2012, Peer-reviewed
- Genetically encoded probes for optical imaging of brain electrical activityAmelie Perron; Walther Akemann; Hiroki Mutoh; Thomas KnoepfelOPTOGENETICS: TOOLS FOR CONTROLLING AND MONITORING NEURONAL ACTIVITY, 2012, Peer-reviewed
- Optogenetic monitoring of membrane potentialsHiroki Mutoh; Amelie Perron; Walther Akemann; Yuka Iwamoto; Thomas KnoepfelEXPERIMENTAL PHYSIOLOGY, Jan. 2011, Peer-reviewed
- Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteinsWalther Akemann; Hiroki Mutoh; Amelie Perron; Jean Rossier; Thomas KnoepfelNATURE METHODS, Aug. 2010, Peer-reviewed
- Red-Shifted Voltage-Sensitive Fluorescent ProteinsAmelie Perron; Hiroki Mutoh; Thomas Launey; Thomas KnopfelCHEMISTRY & BIOLOGY, Dec. 2009, Peer-reviewed
- Exploration of fluorescent protein voltage probes based on circularly permuted fluorescent proteinsSunita Ghimire Gautam; Amelie Perron; Hiroki Mutoh; Thomas KnöpfelFrontiers in Neuroengineering, 13 Oct. 2009, Peer-reviewed
- Second and third generation voltage-sensitive fluorescent proteins for monitoring membrane potentialAmelie Perron; Hiroki Mutoh; Walther Akemann; Sunita Ghimire Gautam; Dimitar Dimitrov; Yuka Iwamoto; Thomas KnöpfelFrontiers in Molecular Neuroscience, 22 Jun. 2009, Peer-reviewed
- Spectrally-Resolved Response Properties of the Three Most Advanced FRET Based Fluorescent Protein Voltage ProbesHiroki Mutoh; Amelie Perron; Dimitar Dimitrov; Yuka Iwamoto; Walther Akemann; Dmitriy M. Chudakov; Thomas KnoepfelPLOS ONE, Feb. 2009, Peer-reviewed
- Genetically encoded fluorescent sensors of membrane potentialB. J. Baker; H. Mutoh; D. Dimitrov; W. Akemann; A. Perron; Y. Iwamoto; L. Jin; L. B. Cohen; E. Y. Isacoff; V. A. Pieribone; T. Hughes; T. KnopfelBRAIN CELL BIOLOGY, Aug. 2008, Peer-reviewed
- NTS2 modulates the intracellular distribution and trafficking of NTS1 via heterodimerizationAmelie Perron; Nadder Sharif; Philippe Sarret; Thomas Stroh; Alain BeaudetBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Feb. 2007, Peer-reviewed
- Sustained neurotensin exposure promotes cell surface recruitment of NTS2 receptorsA Perron; N Sharif; L Gendron; M Lavallee; T Stroh; J Mazella; A BeaudetBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, May 2006, Peer-reviewed
- Potent spinal analgesia elicited through stimulation of NTS2 neurotensin receptorsP Sarret; MJ Esdaile; A Perron; J Martinez; T Stroh; A BeaudetJOURNAL OF NEUROSCIENCE, Sep. 2005, Peer-reviewed
- Identification and functional characterization of a 5-transmembrane domain variant isoform of the NTS2 neurotensin receptor in rat central nervous systemAL Perron; P Sarret; L Gendron; T Stroh; A BeaudetJOURNAL OF BIOLOGICAL CHEMISTRY, Mar. 2005, Peer-reviewed
- Low-affinity neurotensin receptor (NTS2) signaling: Internalization-dependent activation of extracellular signal-regulated kinases 1/2L Gendron; A Perron; MD Payet; N Gallo-Payet; P Sarret; A BeaudetMOLECULAR PHARMACOLOGY, Dec. 2004, Peer-reviewed
- Agonist-independent desensitization and internalization of the human platelet-activating factor receptor by coumermycin-gyrase B-induced dimerizationA Perron; ZG Chen; D Gingras; DJ Dupre; J Stankova; M Rola-PleszczynskiJOURNAL OF BIOLOGICAL CHEMISTRY, Jul. 2003, Peer-reviewed
- Immunohistochemical distribution of NTS2 neurotensin receptors in the rat central nervous systemP Sarret; A Perron; T Stroh; A BeaudetJOURNAL OF COMPARATIVE NEUROLOGY, Jul. 2003, Peer-reviewed
- Neuropeptide Y-induced contraction is mediated by NPY Y2 and Y4 receptors in rat colonPheng LH; Perron A; Quirion R; Cadieux A; Fauchère JL; Dumont Y; Regoli DEuropean Journal of Pharmacology, 1998, Peer-reviewed
Misc.
- Optogenetic electrophysiologyWalther Akemann; Amelie Perron; Hiroki Mutoh; Thomas KnoepfelEUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, Aug. 2011
External funds: Kakenhi
- Small Bioactive Molecules for Orchestrating Embryonic Stem Cell DifferentiationGrant-in-Aid for Young Scientists (B)Kyoto UniversityAMELIE PERRONFrom 01 Apr. 2013, To 31 Mar. 2015, Project ClosedSAR Studies;Hes1;Regenerative Medicine;Stem Cells;Oscillations;Microarray;Transcription;Gro/TLE;Embryonic;Hypoxia;Regenerative medicine;Transcription factors;Stem cells
- Live and Let Die: Orchestrating Aggregation of Eye Pigments with Organic MoleculesGrant-in-Aid for Scientific Research (C)Basic Section 37020:Chemistry and chemical methodology of biomolecules-relatedKyoto UniversityPERRON AMELIEFrom 01 Apr. 2023, To 31 Mar. 2026, Grantedsmall molecules;self-assembly;chemical libraries;aggregation;photodamage
External funds: others
list
Last Updated :2023/09/22
Education
Teaching subject(s)
- From 01 Apr. 2023, To 31 Mar. 2024Everyday Life Chemistry-E2N362, Fall, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Organic Chemistry of Life-E2N361, Spring, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Basic Organic Chemistry II-E2N369, Fall, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Basic Organic Chemistry I-E2N368, Spring, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Research Proposal Writing Practice B8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2023, To 31 Mar. 2024Research Proposal Writing Practice A8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2023, To 31 Mar. 2024Pharmaceutical Laboratory Coaching Practice A8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2023, To 31 Mar. 2024Medicinal Frontier Science Research B8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2023, To 31 Mar. 2024Medicinal Frontier Science Research A8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2023, To 31 Mar. 2024Seminar on Critical Reading of Scientific Papers A8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Seminar on Critical Reading of Scientific Papers B8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Research Proposal Writing Practice A8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2022, To 31 Mar. 2023Everyday Life Chemistry-E2N362, Fall, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Seminar on Critical Reading of Scientific Papers A8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Basic Organic Chemistry II-E2N369, Fall, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Pharmaceutical Laboratory Coaching Practice A8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2022, To 31 Mar. 2023Basic Organic Chemistry I-E2N368, Spring, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Medical Frontier Science Research A8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2022, To 31 Mar. 2023Organic Chemistry of Life-E2N361, Spring, Institute for Liberal Arts and Sciences, 2
- From Apr. 2014, To Mar. 2015Basic Organic Chemistry ASpring, 全学共通科目
- From Apr. 2014, To Mar. 2015Basic Organic Chemistry BFall, 全学共通科目
- From Apr. 2014, To Mar. 2015Organic Chemistry of LifeSpring, 全学共通科目
- From Apr. 2014, To Mar. 2015Everyday Life ChemistryFall, 全学共通科目
- From Apr. 2015, To Mar. 2016Basic Organic Chemistry ISpring, 全学共通科目
- From Apr. 2015, To Mar. 2016Basic Organic Chemistry IIFall, 全学共通科目
- From Apr. 2015, To Mar. 2016Everyday Life ChemistryFall, 全学共通科目
- From Apr. 2015, To Mar. 2016Organic Chemistry of LifeSpring, 全学共通科目
- From Apr. 2016, To Mar. 2017Basic Organic Chemistry I-E2Spring, 全学共通科目
- From Apr. 2016, To Mar. 2017Basic Organic Chemistry II-E2Fall, 全学共通科目
- From Apr. 2016, To Mar. 2017Everyday Life Chemistry-E2Fall, 全学共通科目
- From Apr. 2016, To Mar. 2017Organic Chemistry of Life-E2Spring, 全学共通科目
- From Apr. 2017, To Mar. 2018Basic Organic Chemistry I-E2Spring, 全学共通科目
- From Apr. 2017, To Mar. 2018Basic Organic Chemistry II-E2Fall, 全学共通科目
- From Apr. 2017, To Mar. 2018Everyday Life Chemistry-E2Fall, 全学共通科目
- From Apr. 2017, To Mar. 2018Organic Chemistry of Life-E2Spring, 全学共通科目
- From Apr. 2018, To Mar. 2019Basic Organic Chemistry I-E2Spring, 全学共通科目
- From Apr. 2018, To Mar. 2019Basic Organic Chemistry II-E2Fall, 全学共通科目
- From Apr. 2018, To Mar. 2019Everyday Life Chemistry-E2Fall, 全学共通科目
- From Apr. 2018, To Mar. 2019Organic Chemistry of Life-E2Spring, 全学共通科目
- From Apr. 2019, To Mar. 2020Basic Organic Chemistry I-E2Spring, 全学共通科目
- From Apr. 2019, To Mar. 2020Basic Organic Chemistry II-E2Fall, 全学共通科目
- From Apr. 2019, To Mar. 2020Everyday Life Chemistry-E2Fall, 全学共通科目
- From Apr. 2019, To Mar. 2020Organic Chemistry of Life-E2Spring, 全学共通科目
- From Apr. 2020, To Mar. 2021Basic Organic Chemistry I-E2Spring, 全学共通科目
- From Apr. 2020, To Mar. 2021Basic Organic Chemistry II-E2Fall, 全学共通科目
- From Apr. 2020, To Mar. 2021Everyday Life Chemistry-E2Fall, 全学共通科目
- From Apr. 2020, To Mar. 2021Organic Chemistry of Life-E2Spring, 全学共通科目
- From Apr. 2021, To Mar. 2022Basic Organic Chemistry II-E2Fall, 全学共通科目
- From Apr. 2021, To Mar. 2022Everyday Life Chemistry-E2Fall, 全学共通科目
