Basic Information

Affiliated programs (koza)

• Graduate School of Medicine, 医学専攻 幹細胞遺伝学, 助教
• Graduate School of Medicine, 医科学専攻 幹細胞遺伝学, 助教

Academic Degree

• 修士（理学）(関西学院大学)
• 博士（生体情報）(名古屋市立大学)

ID,URL

• ORCID ID

  0000-0002-8892-1386

• J-Global ID

  202001003537786952

• Researcher number

  50846508

researchmap URL

• https://researchmap.jp/chr18

Research

Research Areas

• Life sciences, Molecular biology

Papers

• DEAD/H Box 5 (DDX5) Augments E2F1-Induced Cell Death Independent of the Tumor Suppressor p53

  Rinka Nakajima; Yaxuan Zhou; Mashiro Shirasawa; Naoyasu Nishimura; Lin Zhao; Mariana Fikriyanti; Yuki Kamiya; Ritsuko Iwanaga; Andrew P. Bradford; Kaori Shinmyozu; Gohei Nishibuchi; Jun-ichi Nakayama; Kenta Kurayoshi; Keigo Araki; Kiyoshi Ohtani

  International Journal of Molecular Sciences, 10 Dec. 2024

  
• Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia.

  Kazunari Aoki; Mizuki Hyuga; Yusuke Tarumoto; Gohei Nishibuchi; Atsushi Ueda; Yotaro Ochi; Seiichi Sugino; Takashi Mikami; Hirokazu Kobushi; Itaru Kato; Koshi Akahane; Takeshi Inukai; Akifumi Takaori-Kondo; Junko Takita; Seishi Ogawa; Kosuke Yusa

  Blood, 03 Nov. 2023

  
• Dominant-negative variants in CBX1 cause a neurodevelopmental disorder.

  Yukiko Kuroda; Aiko Iwata-Otsubo; Kerith-Rae Dias; Suzanna E L Temple; Koji Nagao; Lachlan De Hayr; Ying Zhu; Shin-Ya Isobe; Gohei Nishibuchi; Sarah K Fiordaliso; Yuki Fujita; Alyssa L Rippert; Samuel W Baker; Marco L Leung; Daniel C Koboldt; Adele Harman; Beth A Keena; Izumi Kazama; Gopinath Musuwadi Subramanian; Kandamurugu Manickam; Betsy Schmalz; Maeson Latsko; Elaine H Zackai; Matt Edwards; Carey-Anne Evans; Matthew C Dulik; Michael F Buckley; Toshihide Yamashita; W Timothy O'Brien; Robert J Harvey; Chikashi Obuse; Tony Roscioli; Kosuke Izumi

  Genetics in medicine : official journal of the American College of Medical Genetics, Jul. 2023

  
• H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly.

  Eriko Oya; Reiko Nakagawa; Yuriko Yoshimura; Mayo Tanaka; Gohei Nishibuchi; Shinichi Machida; Atsuko Shirai; Karl Ekwall; Hitoshi Kurumizaka; Hideaki Tagami; Jun-Ichi Nakayama

  EMBO reports, 04 Oct. 2019, Peer-reviewed

  
• Mitotic phosphorylation of HP1α regulates its cell cycle-dependent chromatin binding.

  Nishibuchi G; Machida S; Nakagawa R; Yoshimura Y; Hiragami-Hamada K; Abe Y; Kurumizaka H; Tagami H; Nakayama JI

  Journal of biochemistry, May 2019, Peer-reviewed

  
• The molecular basis of the organization of repetitive DNA-containing constitutive heterochromatin in mammals

  Gohei Nishibuchi; Jerome Dejardin

  CHROMOSOME RESEARCH, Mar. 2017, Peer-reviewed

  
• N-terminal phosphorylation of HP1 alpha increases its nucleosome-binding specificity

  Gohei Nishibuchi; Shinichi Machida; Akihisa Osakabe; Hiromu Murakoshi; Kyoko Hiragami-Hamada; Reiko Nakagawa; Wolfgang Fischle; Yoshifumi Nishimura; Hitoshi Kurumizaka; Hideaki Tagami; Jun-ichi Nakayama

  NUCLEIC ACIDS RESEARCH, Nov. 2014, Peer-reviewed

  
• Physical and Functional Interactions between the Histone H3K4 Demethylase KDM5A and the Nucleosome Remodeling and Deacetylase (NuRD) Complex

  Gohei Nishibuchi; Yukimasa Shibata; Tomohiro Hayakawa; Noriyo Hayakawa; Yasuko Ohtani; Kaori Sinmyozu; Hideaki Tagami; Jun-ichi Nakayama

  JOURNAL OF BIOLOGICAL CHEMISTRY, Oct. 2014, Peer-reviewed

  
• Biochemical and structural properties of heterochromatin protein 1: understanding its role in chromatin assembly

  Gohei Nishibuchi; Jun-ichi Nakayama

  JOURNAL OF BIOCHEMISTRY, Jul. 2014, Peer-reviewed

  

Misc.

• ヒストン脱メチル化酵素RBP2と相互作用する因子の探索と転写調節における役割の解明

  西淵剛平; 早川典代; 大谷寧子; 柴田幸政; 新名主カオリ; 早川智博; 中山潤一; 中山潤一

  日本分子生物学会年会プログラム・要旨集(Web), 2012

  
• 分裂酵母のヘテロクロマチンを制御するヒストン修飾のクロストーク

  大屋恵梨子; 中川れい子; 吉村ゆり子; 田中万葉; 西淵剛平; 町田晋一; 胡桃坂仁志; 田上英明; 中山潤一

  日本遺伝学会大会プログラム・予稿集, 2019

  
• 高次クロマチン構造形成におけるヒストン修飾のクロストーク

  大屋恵梨子; 田中万葉; 西淵剛平; 中川れい子; 町田晋一; 胡桃坂仁志; 田上英明; 中山潤一

  日本分子生物学会年会プログラム・要旨集(Web), 2016

  
• HP1のリン酸化はH3K9me3nucleosomeに対する結合特異性を制御している

  西淵剛平; 町田晋一; 越阪部晃永; 村越大夢; 浜田京子; 中川れい子; WOLFGANG Fischle; 胡桃坂仁志; 田上英明; 中山潤一

  日本生化学会大会(Web), 2014

  
• ヘテロクロマチンタンパク質HP1のリン酸化修飾と高次クロマチン構造形成のダイナミクス

  西淵剛平; 町田晋一; 越坂部晃永; 中川れい子; 胡桃坂仁志; 中山潤一

  日本分子生物学会年会プログラム・要旨集(Web), 2013

  
• ヘテロクロマチンタンパク質HP1による高次クロマチン構造形成のメカニズム

  西淵剛平; 町田晋一; 越阪部晃永; 中川れい子; 須賀則之; 胡桃坂仁志; 中山潤一

  日本生化学会大会(Web), 2013

  

Awards

• 07 Jul. 2020

  The Japanese Biochemical Society , JB論文賞

External funds: Kakenhi

• Dynamic analysis of MLL fusion protein in acute myeloid leukemia cells using proximity labeling technique

  Grant-in-Aid for Early-Career Scientists

  Basic Section 43010:Molecular biology-related

  Kyoto University

  Gohei Nishibuchi

  From 01 Apr. 2021, To 31 Mar. 2024, Project Closed

  エピジェネティクス;急性骨髄性白血病;ゲノム部位特異的プロテオミクス;クロマチン

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K15016/
• Revealing the molecular mechanisms underlying constitutive heterochromatin transition during cellular differentiation

  Grant-in-Aid for Research Activity Start-up

  0701:Biology at molecular to cellular levels, and related fields

  Kyoto University

  GOHEI NISHIBUCHI

  From 30 Aug. 2019, To 31 Mar. 2021, Project Closed

  ヘテロクロマチン;エピジェネティクス;クロマチンダイナミクス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K23724/

Education

Teaching subject(s)

• From 01 Apr. 2023, To 31 Mar. 2024

  ILAS Seminar

  Z001, Spring, Institute for Liberal Arts and Sciences, 2

Administration

Faculty management (title, position)

• From 01 Apr. 2021, To 31 Mar. 2023

  病院構内実験配水系管理委員会