Basic Information

Academic Degree

• 博士（医学）(京都大学)

ID,URL

• J-Global ID

  201401068582609383

researchmap URL

• https://researchmap.jp/7000010493

Research

Research Areas

• Life sciences, Hematology and oncology

Papers

• Modelling and drug targeting of a myeloid neoplasm with atypical 3q26/MECOM rearrangement using patient-specific iPSCs.

  Momoko Nakamura; Kazuhisa Chonabayashi; Megumi Narita; Yasuko Matsumura; Misato Nishikawa; Yotaro Ochi; Yasuhito Nannya; Masakatsu Hishizawa; Daichi Inoue; Ruud Delwel; Seishi Ogawa; Akifumi Takaori-Kondo; Yoshinori Yoshida

  British journal of haematology, 26 Aug. 2024, Peer-reviewed, Lead author, Corresponding author

  
• [Concentration of gilteritinib in the cerebrospinal fluid of a patient with relapsed FLT3-ITD positive acute myeloid leukemia with optic nerve involvement].

  Yuta Suzuki; Toshio Kitawaki; Yasuyuki Arai; Shunsaku Nakagawa; Kazuhisa Chonabayashi; Yasuhito Nannya; Kouhei Yamashita; Seishi Ogawa; Akifumi Takaori-Kondo

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2024, Peer-reviewed

  
• Juvenile Hemochromatosis With Non-transfused Hemolytic Anemia Caused by a De Novo PIEZO1 Gene Mutation.

  Shinsaku Imashuku; Shin-Ichiro Suemori; Manabu Wakamatsu; Yusuke Okuno; Hideki Muramatsu; Shigeru Makino; Takashi Miyoshi; Kazuhisa Chonabayashi; Hitoshi Kanno

  Journal of pediatric hematology/oncology, 01 May 2023, Peer-reviewed

  
• Resistance of KIR Ligand–Missing Leukocytes to NK Cells in Vivo in Patients with Acquired Aplastic Anemia

  Thi Nguyen, M.A.; Hosokawa, K.; Yoroidaka, T.; Maruyama, H.; Espinoza, J.L.; Elbadry, M.I.; Mohiuddin, M.; Tanabe, M.; Katagiri, T.; Nakagawa, N.; Chonabayashi, K.; Yoshida, Y.; Arima, N.; Kashiwase, K.; Saji, H.; Ogawa, S.; Nakao, S.

  Brazilian Business Review, 2021

  
• DDX41の病的バリアントと体細胞変異の機能的差異

  中村 桃子; 蝶名林 和久; 丹羽 諒; Woltjen Knut; 越智 陽太郎; 南谷 泰仁; 小川 誠司; 高折 晃史; 吉田 善紀

  日本血液学会学術集会, Oct. 2023

  
• ロングリードシークエンスを用いたder(1;7)(q10;p10)を伴う骨髄異形成症候群における染色体切断点の検索

  須川 正啓; 奥田 瑠璃花; 越智 陽太郎; 南谷 泰仁; 中村 航; Mateos Raul; 飯田 直子; 千葉 健一; 岡田 愛; 木村 啓佑; 辻村 太郎; 蝶名林 和久; 山本 拓也; 吉田 善紀; 高折 晃史; 加藤 元博; 小川 誠司; 白石 友一

  日本血液学会学術集会, Oct. 2023

  
• ロングリードシークエンスを用いたder(1;7)(q10;p10)を伴う骨髄異形成症候群における染色体切断点の検索(Characterizing the breakpoint of an unbalanced translocation der(1;7)(q10;p10) with long-read sequence technology)

  須川 正啓; 奥田 瑠璃花; 越智 陽太郎; 南谷 泰仁; 中村 航; マテオス・ラウル; 飯田 直子; 千葉 健一; 岡田 愛; 木村 啓佑; 辻村 太郎; 蝶名林 和久; 高折 晃史; 加藤 元博; 小川 誠司; 白石 友一

  日本癌学会総会記事, Sep. 2023

  
• がん研究における女性研究者 不均衡転座der(1;7)(q10;p10)を有するMDSと関連疾患の特徴(Unbalanced translocation der(1;7)(q10;p10) as a distinct subtype in myelodysplastic syndromes)

  奥田 瑠璃花; 越智 陽太郎; 蝶名林 和久; 眞田 昌; 半田 寛; 白石 友一; 千葉 滋; 石川 隆之; 大屋敷 一馬; 熱田 由子; 宮野 悟; 牧島 秀樹; 南谷 泰仁; 小川 誠司

  日本癌学会総会記事, Sep. 2022

  
• CD151 expression marks atrial- and ventricular- differentiation from human induced pluripotent stem cells.

  Misato Nakanishi-Koakutsu; Kenji Miki; Yuki Naka; Masako Sasaki; Takayuki Wakimizu; Stephanie C Napier; Chikako Okubo; Megumi Narita; Misato Nishikawa; Reo Hata; Kazuhisa Chonabayashi; Akitsu Hotta; Kenichi Imahashi; Tomoyuki Nishimoto; Yoshinori Yoshida

  Communications biology, 28 Feb. 2024, Peer-reviewed

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• Successful treatment with cyclosporine of pure red cell aplasia induced by obinutuzumab bendamustine therapy.

  Yutaka Shimazu; Chisaki Mizumoto; Kazuhisa Chonabayashi; Yuta Hanyu; Junya Kanda; Akifumi Takaori-Kondo

  Annals of hematology, 27 Apr. 2023, Peer-reviewed

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• Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

  Jingshan Gao; Takeru Makiyama; Yuta Yamamoto; Takuya Kobayashi; Hisaaki Aoki; Thomas L Maurissen; Yimin Wuriyanghai; Asami Kashiwa; Tomohiko Imamura; Takanori Aizawa; Hai Huang; Hirohiko Kohjitani; Misato Nishikawa; Kazuhisa Chonabayashi; Megumi Fukuyama; Hiromi Manabe; Kouichi Nakau; Tsutomu Wada; Koichi Kato; Futoshi Toyoda; Yoshinori Yoshida; Naomasa Makita; Knut Woltjen; Seiko Ohno; Nagomi Kurebayashi; Takashi Murayama; Takashi Sakurai; Minoru Horie; Takeshi Kimura

  Circulation. Arrhythmia and electrophysiology, 03 Mar. 2023, Peer-reviewed

  
• がん研究における女性研究者 不均衡転座der(1;7)(q10;p10)を有するMDSと関連疾患の特徴(Unbalanced translocation der(1;7)(q10;p10) as a distinct subtype in myelodysplastic syndromes)

  奥田 瑠璃花; 越智 陽太郎; 蝶名林 和久; 眞田 昌; 半田 寛; 白石 友一; 千葉 滋; 石川 隆之; 大屋敷 一馬; 熱田 由子; 宮野 悟; 牧島 秀樹; 南谷 泰仁; 小川 誠司

  日本癌学会総会記事, Sep. 2022

  
• Hematopoietic stem progenitor cells with malignancy-related gene mutations in patients with acquired aplastic anemia are characterized by the increased expression of CXCR4.

  Takamasa Katagiri; Jorge Luis Espinoza; Mizuho Uemori; Honoka Ikeda; Kohei Hosokawa; Ken Ishiyama; Takeshi Yoroidaka; Tatsuya Imi; Hiroyuki Takamatsu; Tatsuhiko Ozawa; Hiroyuki Kishi; Yasuhiko Yamamoto; Mahmoud Ibrahim Elbadry; Yoshinori Yoshida; Kazuhisa Chonabayashi; Katsuto Takenaka; Koichi Akashi; Yasuhito Nannya; Seishi Ogawa; Shinji Nakao

  EJHaem, Aug. 2022, Peer-reviewed

  
• Disrupted Cav1.2 Selectivity Causes Overlapping Long QT and Brugada Syndrome Phenotypes in CACNA1C-E1115K iPS Cell Model.

  Asami Kashiwa; Takeru Makiyama; Hirohiko Kohjitani; Thomas L Maurissen; Taisuke Ishikawa; Yuta Yamamoto; Yimin Wuriyanghai; Jingshan Gao; Hai Huang; Tomohiko Imamura; Takanori Aizawa; Misato Nishikawa; Kazuhisa Chonabayashi; Hiroyuki Mishima; Seiko Ohno; Futoshi Toyoda; Seiichi Sato; Koh-Ichiro Yoshiura; Kazuhiro Takahashi; Yoshinori Yoshida; Knut Woltjen; Minoru Horie; Naomasa Makita; Takeshi Kimura

  Heart rhythm, 22 Aug. 2022, Peer-reviewed

  
• Purification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sorting.

  Yuta Tsujisaka; Takeshi Hatani; Chikako Okubo; Ryo Ito; Azuma Kimura; Megumi Narita; Kazuhisa Chonabayashi; Shunsuke Funakoshi; Antonio Lucena-Cacace; Taro Toyoda; Kenji Osafune; Takeshi Kimura; Hirohide Saito; Yoshinori Yoshida

  Stem cell reports, 12 Jul. 2022, Peer-reviewed

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• The GPI-anchored protein CD109 protects hematopoietic progenitor cells from undergoing erythroid differentiation induced by TGF-β

  Mikoto Tanabe; Kohei Hosokawa; Mai Anh Thi Nguyen; Noriharu Nakagawa; Kana Maruyama; Noriaki Tsuji; Ryota Urushihara; Luis Espinoza; Mahmoud I. Elbadry; Md Mohiuddin; Takamasa Katagiri; Masanori Ono; Hiroshi Fujiwara; Kazuhisa Chonabayashi; Yoshinori Yoshida; Hirohito Yamazaki; Atsushi Hirao; Shinji Nakao

  Leukemia, Mar. 2022, Peer-reviewed

  
• Azacitidine is a potential therapeutic drug for pyridoxine-refractory female X-linked sideroblastic anemia

  Yuki Morimoto; Kazuhisa Chonabayashi; Hiroshi Kawabata; Chikako Okubo; Makiko Yamasaki-Morita; Misato Nishikawa; Megumi Narita; Azusa Inagaki; Kayoko Nakanishi; Miki Nagao; Akifumi Takaori-Kondo; Yoshinori Yoshida

  Blood Advances, 22 Feb. 2022, Peer-reviewed, Corresponding author

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• ETNK1変異の有無を特徴とするder(1;7)(q10;p10)を伴う骨髄異形成症候群

  奥田 瑠璃花; 南谷 泰仁; 越智 陽太郎; 蝶名林 和久; 牧島 秀樹; 永田 安伸; 真田 昌; 白石 友一; 宮野 悟; 熱田 由子; 笠原 千嗣; 半田 寛; 千葉 滋; 大屋敷 一馬; 小川 誠司

  日本癌学会総会記事, Sep. 2021

  
• ETNK1 mutations defines a subclass of der(1;7)(q10;p10) in myelodysplastic syndromes(和訳中)

  奥田 瑠璃花; 南谷 泰人; 越智 陽太郎; 蝶名林 和久; 牧島 秀樹; 吉里 哲一; 永田 安伸; 竹田 淳恵; 吉田 健一; 眞田 昌; 昆 彩奈; 白石 雄一; 宮野 悟; 熱田 由子; 笠原 千嗣; 半田 寛; 千葉 滋; 大屋敷 一馬; 吉田 善紀; 小川 誠司

  日本血液学会学術集会, Sep. 2021

  
• Elucidating the pathophysiology of AML with atypical 3q26 translocations using patient-derived iPSCs(和訳中)

  中村 桃子; 蝶名林 和久; 森本 有紀; 越智 陽太郎; 南谷 泰仁; 北脇 年雄; 菱澤 方勝; 小川 誠司; 高折 晃史; 吉田 善紀

  日本血液学会学術集会, Sep. 2021

  
• 骨髄異形成症候群におけるder(1;7)の民族的、臨床的、遺伝的特徴(Distinct ethnic, clinical, and genetic characteristics of der(1;7) in myelodysplastic syndromes)

  奥田 瑠璃花; 南谷 泰仁; 越智 陽太郎; 蝶名林 和久; Creignou Maria; 牧島 秀樹; 竹田 淳恵; 昆 彩奈; 宮野 悟; 半田 寛; 千葉 滋; 大屋敷 一馬; Haferlach Torsten; Lindberg Eva; 小川 誠司

  日本癌学会総会記事, Oct. 2020

  
• 骨髄異形成症候群におけるder(1;7)の民族的、臨床的、遺伝的特徴(Distinct ethnic, clinical, and genetic characteristics of der(1;7) in myelodysplastic syndromes)

  奥田 瑠璃花; 南谷 泰仁; 越智 陽太郎; 蝶名林 和久; Creignou Maria; 牧島 秀樹; 竹田 淳恵; 昆 彩奈; 宮野 悟; 半田 寛; 千葉 滋; 大屋敷 一馬; Haferlach Torsten; Lindberg Eva; 小川 誠司

  日本癌学会総会記事, Oct. 2020

  
• Resistance of KIR Ligand-Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia.

  Mai Anh Thi Nguyen; Kohei Hosokawa; Takeshi Yoroidaka; Hiroyuki Maruyama; J Luis Espinoza; Mahmoud I Elbadry; Md Mohiuddin; Mikoto Tanabe; Takamasa Katagiri; Noriharu Nakagawa; Kazuhisa Chonabayashi; Yoshinori Yoshida; Nobuyoshi Arima; Koichi Kashiwase; Hiroh Saji; Seishi Ogawa; Shinji Nakao

  ImmunoHorizons, 17 Jul. 2020, Peer-reviewed

  
• Successful treatment of Hodgkin lymphoma-like EBV-associated post-transplant lymphoproliferative disorder following allogeneic hematopoietic stem cell transplantation with nivolumab.

  Fumiya Wada; Tadakazu Kondo; Momoko Nakamura; Kazuhisa Chonabayashi; Momoko Nishikori; Masakatsu Hishizawa; Kouhei Yamashita; Akifumi Takaori-Kondo

  Annals of hematology, Apr. 2020, Peer-reviewed

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• Propranolol Attenuates Late Sodium Current in a Long QT Syndrome Type 3-Human Induced Pluripotent Stem Cell Model.

  Sayako Hirose; Takeru Makiyama; Dario Melgari; Yuta Yamamoto; Yimin Wuriyanghai; Fumika Yokoi; Suguru Nishiuchi; Takeshi Harita; Mamoru Hayano; Hirohiko Kohjitani; Jingshan Gao; Asami Kashiwa; Misato Nishikawa; Jie Wu; Jun Yoshimoto; Kazuhisa Chonabayashi; Seiko Ohno; Yoshinori Yoshida; Minoru Horie; Takeshi Kimura

  Frontiers in cell and developmental biology, 2020, Peer-reviewed

  
• A frequent nonsense mutation in exon 1 across certain HLA-A and -B alleles in leukocytes of patients with acquired aplastic anemia.

  Hiroki Mizumaki; Kazuyoshi Hosomichi; Kohei Hosokawa; Takeshi Yoroidaka; Tatsuya Imi; Yoshitaka Zaimoku; Takamasa Katagiri; Mai Anh Thi Nguyen; Dung Cao Tran; Mahmoud Ibrahim Yousef Elbadry; Kazuhisa Chonabayashi; Yoshinori Yoshida; Hiroyuki Takamatsu; Tatsuhiko Ozawa; Fumihiro Azuma; Hiroyuki Kishi; Yoichi Fujii; Seishi Ogawa; Atsushi Tajima; Shinji Nakao

  Haematologica, 2020, Peer-reviewed

  
• Erratum: Optical recording of action potentials in human induced pluripotent stem cell-derived cardiac single cells and monolayers generated from long qt syndrome type 1 patients (Stem Cells International (2019) 2019 (7532657) DOI: 10.1155/2019/7532657)

  Tadashi Takaki; Azusa Inagaki; Kazuhisa Chonabayashi; Keiji Inoue; Kenji Miki; Seiko Ohno; Takeru Makiyama; Minoru Horie; Yoshinori Yoshida

  Stem Cells International, 2020, Peer-reviewed

  
• Acute myeloid leukemia with a cryptic NUP98/PRRX2 rearrangement developing after low-dose methotrexate therapy for rheumatoid arthritis.

  Kazuhisa Chonabayashi; Yoshinori Yoshida; Toshio Kitawaki; Yasuhito Nannya; Momoko Nakamura; Shinichiro Oshima; Masakatsu Hishizawa; Kouhei Yamashita; Seishi Ogawa; Akifumi Takaori-Kondo

  Annals of hematology, Dec. 2019, Peer-reviewed, Lead author, Corresponding author

  
• Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia.

  Mahmoud I Elbadry; Hiroki Mizumaki; Kohei Hosokawa; J Luis Espinoza; Noriharu Nakagawa; Kazuhisa Chonabayashi; Yoshinori Yoshida; Takamasa Katagiri; Kazuyoshi Hosomichi; Yoshitaka Zaimoku; Tatsuya Imi; Mai Anh Thi Nguyen; Youichi Fujii; Atsushi Tajima; Seishi Ogawa; Katsuto Takenaka; Koichi Akashi; Shinji Nakao

  Haematologica, Oct. 2019, Peer-reviewed

  
• Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients.

  Tadashi Takaki; Azusa Inagaki; Kazuhisa Chonabayashi; Keiji Inoue; Kenji Miki; Seiko Ohno; Takeru Makiyama; Minoru Horie; Yoshinori Yoshida

  Stem cells international, 2019, Peer-reviewed

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• Complex aberrant splicing in the induced pluripotent stem cell-derived cardiomyocytes from a patient with long QT syndrome carrying KCNQ1-A344Aspl mutation.

  Yimin Wuriyanghai; Takeru Makiyama; Kenichi Sasaki; Tsukasa Kamakura; Yuta Yamamoto; Mamoru Hayano; Takeshi Harita; Suguru Nishiuchi; Jiarong Chen; Hirohiko Kohjitani; Sayako Hirose; Fumika Yokoi; Jingshan Gao; Kazuhisa Chonabayashi; Ken Watanabe; Seiko Ohno; Yoshinori Yoshida; Takeshi Kimura; Minoru Horie

  Heart rhythm, Oct. 2018, Peer-reviewed

  
• Lamin A/C関連心筋症の病態生理学的メカニズム分析のためのホモ接合性Lamin A/C欠損ヒト人工多能性幹細胞モデルの開発(Development of Homozygous LaminA/C Deficient Human Induced Pluripotent Stem Cell Model for Analyzing the Pathophysiological Mechanism of Lamin A/C-related Cardiomyopathy)

  Wuriyanghai Yimin; Makiyama Takeru; Nishiuchi Suguru; Yamamoto Yuta; Hirose Sayako; Hayano Mamoru; Harita Takeshi; Kohjitani Hirohiko; Yokoi Fumika; Chonabayashi Kazuhisa; Yoshida Yoshinori; Ohno Seiko; Horie Minoru; Kimura Takeshi

  日本循環器学会学術集会抄録集, Mar. 2018

  
• CALM2-D134H変異を有するQT延長症候群のヒトiPS細胞モデルではL型Ca2+チャネル不活性化がみられなかった(The Inactivation of L-type Ca2+ Cannel was Impaired in Human iPS Cell Model of Long-QT Syndrome with CALM2-D134H Mutation)

  Yamamoto Yuta; Makiyama Takeru; Harita Takeshi; Hayano Mamoru; Nishiuchi Suguru; Wuriyanghai Yimin; Kohjitani Hirohiko; Hirose Sayako; Yokoi Fumika; Ishikawa Taisuke; Ohno Seiko; Chonabayashi Kazuhisa; Suda Kenji; Yoshida Yoshinori; Horie Minoru; Makita Naomasa; Kimura Takeshi

  日本循環器学会学術集会抄録集, Mar. 2018

  
• Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack.

  Espinoza JL; Elbadry MI; Chonabayashi K; Yoshida Y; Katagiri T; Harada K; Nakagawa N; Zaimoku Y; Imi T; Takamatsu H; Ozawa T; Maruyama H; Hassanein HA; Khalifa A Noreldin A; Takenaka K; Akashi K; Hamana H; Kishi H; Akatsuka Y; Nakao S

  Blood advances, Feb. 2018, Peer-reviewed

  
• Erratum: Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack (Blood Adv) (2018) 2:4 (390-400) DOI: 10.1182/bloodadvances.201701334)

  Espinoza, J.L.; Elbadry, M.I.; Chonabayashi, K.; Yoshida, Y.; Katagiri, T.; Harada, K.; Nakagawa, N.; Zaimoku, Y.; Imi, T.; Takamatsu, H.; Ozawa, T.; Maruyama, H.; Hassanein, H.A.; Noreldin, A.K.A.; Takenaka, K.; Akashi, K.; Hamana, H.; Kishi, H.; Akatsuka, Y.; Nakao, S.

  Blood Advances, 2018, Peer-reviewed

  
• Development of a Patient-Derived Induced Pluripotent Stem Cell Model for the Investigation of SCN5A-D1275N-Related Cardiac Sodium Channelopathy

  Mamoru Hayano; Takeru Makiyama; Tsukasa Kamakura; Hiroshi Watanabe; Kenichi Sasaki; Shunsuke Funakoshi; Yimin Wuriyanghai; Suguru Nishiuchi; Takeshi Harita; Yuta Yamamoto; Hirohiko Kohjitani; Sayako Hirose; Fumika Yokoi; Jiarong Chen; Osamu Baba; Takahiro Horie; Kazuhisa Chonabayashi; Seiko Ohno; Futoshi Toyoda; Yoshinori Yoshida; Koh Ono; Minoru Horie; Takeshi Kimura

  CIRCULATION JOURNAL, Dec. 2017, Peer-reviewed

  
• CALM2-D134H Mutation Associated With Long-QT Syndrome Delayed Inactivation of L-type Ca2+ Currents in Human iPS Cells Derived Cardiomyocytes

  Yamamoto Yuta; Makiyama Takeru; Harita Takeshi; Hayano Mamoru; Nishiuchi Suguru; Wuriyanghai Yimin; Kohjitani Hirohiko; Hirose Sayako; Yokoi Fumika; Ishikawa Taisuke; Ohno Seiko; Chonabayashi Kazuhisa; Suda Kenji; Yoshida Yoshinori; Horie Minoru; Makita Naomasa; Kimura Takeshi

  CIRCULATION, 14 Nov. 2017, Peer-reviewed

  
• Human iPSC-Derived Myocyte Mmodel of SCN5A-D1275N-Related Cardiac Sodium Channelopathy Reveals Diminished Sodium Currents Resulting From Enhanced Protein Degradation

  Hayano Mamoru; Makiyama Takeru; Kamakura Tsukasa; Watanabe Hiroshi; Sasaki Kenichi; Funakoshi Shunsuke; Wuriyanghai Yimin; Nishiuchi Suguru; Harita Takeshi; Yamamoto Yuta; Kohjitani Hirohiko; Hirose Sayako; Yokoi Fumika; Chen Jiarong; Baba Osamu; Horie Takahiro; Chonabayashi Kazuhisa; Ohno Seiko; Toyoda Futoshi; Yoshida Yoshinori; Ono Koh; Horie Minoru; Kimura Takeshi

  CIRCULATION, 14 Nov. 2017, Peer-reviewed

  
• Allele-specific ablation rescues electrophysiological abnormalities in a human iPS cell model of long-QT syndrome with a CALM2 mutation

  Yuta Yamamoto; Takeru Makiyama; Takeshi Harita; Kenichi Sasaki; Yimin Wuriyanghai; Mamoru Hayano; Suguru Nishiuchi; Hirohiko Kohjitani; Sayako Hirose; Jiarong Chen; Fumika Yokoi; Taisuke Ishikawa; Seiko Ohno; Kazuhisa Chonabayashi; Hideki Motomura; Yoshinori Yoshida; Minoru Horie; Naomasa Makita; Takeshi Kimura

  HUMAN MOLECULAR GENETICS, May 2017, Peer-reviewed

  
• L型Ca2+チャネル遺伝子変異によるQT延長症候群iPS細胞モデルにおいて、l-cis-DiltiazemはCaチャネル不活性化を改善した(l-cis-diltiazem rescues impaired calcium channel inactivation in an iPSC-model of CACNA1Cassociated long-QT syndrome)

  Harita Takeshi; Makiyama Takeru; Toyoda Futoshi; Sasaki Kenichi; Nishiuchi Suguru; Hayano Mamoru; Yamamoto Yuta; Kohjitani Hirohiko; Wuriyanghai Yimin; Hirose Sayako; Chen Jiarong; Fukuyama Megumi; Chonabayashi Kazuhisa; Ohno Seiko; Yoshida Yoshinori; Ueyama Takeshi; Shimizu Akihiko; Matsuura Hiroshi; Horie Minoru; Kimura Takeshi

  The Journal of Physiological Sciences, Mar. 2017

  
• Reprogramming technology reveals genetic and functional diversity of subclones in myelodysplastic syndromes.

  Chonabayashi K; Yoshida Y; Takaori-Kondo A

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2017, Peer-reviewed, Invited, Lead author

  
• Basic Cardiovascular Science Best Abstract Award: Allele-specific Disruption Rescues Electrophysiological Abnormalities in Human iPS Cell Model of Long-QT Syndrome With a CALM2 Mutation

  Yamamoto Yuta; Makiyama Takeru; Harita Takeshi; Sasaki Kenichi; Hayano Mamoru; Nishiuchi Suguru; Wuriyanghai Yimin; Kohjitani Hirohiko; Hirose Sayako; Chen Jiarong; Ishikawa Taisuke; Motomura Hideki; Ohno Seiko; Chonabayashi Kazuhisa; Yoshida Yoshinori; Horie Minoru; Makita Naomasa; Kimura Takeshi

  CIRCULATION, 11 Nov. 2016, Peer-reviewed

  
• Basic Cardiovascular Science Best Abstract Award: Allele-specific Disruption Rescues Electrophysiological Abnormalities in Human iPS Cell Model of Long-QT Syndrome With a CALM2 Mutation

  Yamamoto Yuta; Makiyama Takeru; Harita Takeshi; Sasaki Kenichi; Hayano Mamoru; Nishiuchi Suguru; Wuriyanghai Yimin; Kohjitani Hirohiko; Hirose Sayako; Chen Jiarong; Ishikawa Taisuke; Motomura Hideki; Ohno Seiko; Chonabayashi Kazuhisa; Yoshida Yoshinori; Horie Minoru; Makita Naomasa; Kimura Takeshi

  CIRCULATION, 11 Nov. 2016, Peer-reviewed

  
• Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity

  Masatoshi Nishizawa; Kazuhisa Chonabayashi; Masaki Nomura; Azusa Tanaka; Masahiro Nakamura; Azusa Inagaki; Misato Nishikawa; Ikue Takei; Akiko Oishi; Koji Tanabe; Mari Ohnuki; Hidaka Yokota; Michiyo Koyanagi-Aoi; Keisuke Okita; Akira Watanabe; Akifumi Takaori-Kondo; Shinya Yamanaka; Yoshinori Yoshida

  CELL STEM CELL, Sep. 2016, Peer-reviewed

  
• Enhanced engraftment, proliferation, and therapeutic potential in heart using optimized human iPSC-derived cardiomyocytes

  Shunsuke Funakoshi; Kenji Miki; Tadashi Takaki; Chikako Okubo; Takeshi Hatani; Kazuhisa Chonabayashi; Misato Nishikawa; Ikue Takei; Akiko Oishi; Megumi Narita; Masahiko Hoshijima; Takeshi Kimura; Shinya Yamanaka; Yoshinori Yoshida

  SCIENTIFIC REPORTS, Jan. 2016, Peer-reviewed

  Access this paper :

  
• Refractory IG kappa/IRF4-positive DLBCL with CDKN2A/2B deletion

  Kazuhisa Chonabayashi; Shigeki Tamori; Masafumi Taniwaki; Haruyuki Fujita; Yayoi Shimazu; Yusuke Matsui; Masakatsu Hishizawa; Kazumasa Usami; Akifumi Takaori-Kondo

  ANNALS OF HEMATOLOGY, May 2014, Peer-reviewed, Lead author, Corresponding author

  
• Successful allogeneic stem cell transplantation with long-term remission of ETV6/FLT3-positive myeloid/lymphoid neoplasm with eosinophilia

  Kazuhisa Chonabayashi; Masakatsu Hishizawa; Masashi Matsui; Tadakazu Kondo; Tatsuharu Ohno; Takayuki Ishikawa; Akifumi Takaori-Kondo

  ANNALS OF HEMATOLOGY, Mar. 2014, Peer-reviewed, Lead author

  
• Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3

  K. Chonabayashi; M. Hishizawa; S. Kawamata; Y. Nagai; T. Ohno; T. Ishikawa; T. Uchiyama; A. Takaori-Kondo

  LEUKEMIA, Jun. 2013, Peer-reviewed, Lead author

  
• MicroRNA-33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE(-/-) Mice

  Takahiro Horie; Osamu Baba; Yasuhide Kuwabara; Yoshimasa Chujo; Shin Watanabe; Minako Kinoshita; Masahito Horiguchi; Tomoyuki Nakamura; Kazuhisa Chonabayashi; Masakatsu Hishizawa; Koji Hasegawa; Noriaki Kume; Masayuki Yokode; Toru Kita; Takeshi Kimura; Koh Ono

  JOURNAL OF THE AMERICAN HEART ASSOCIATION, Dec. 2012, Peer-reviewed

  
• Successful use of second cord blood transplantation to achieve long-term remission in cord blood donor cell-derived AML harboring a FLT3-ITD and an NPM1 mutation

  K. Chonabayashi; T. Kondo; K. Yamamoto; Y. Tanaka; Y. Nagai; M. Hishizawa; A. Takaori-Kondo

  BONE MARROW TRANSPLANTATION, Sep. 2012, Peer-reviewed, Lead author

  
• Kpm/Lats2 is linked to chemosensitivity of leukemic cells through the stabilization of p73

  Masahiro Kawahara; Toshiyuki Hori; Kazuhisa Chonabayashi; Tsutomu Oka; Marius Sudol; Takashi Uchiyama

  BLOOD, Nov. 2008, Peer-reviewed

  
• Sustained complete remission of refractory enteropathy-type T-cell lymphoma following reduced-intensity unrelated cord blood transplantation

  K. Chonabayashi; T. Kondo; Y. Tanaka; T. Ichinohe; T. Ishikawa; T. Uchiyama

  BONE MARROW TRANSPLANTATION, Nov. 2007, Peer-reviewed, Lead author, Corresponding author

  
• Primary large B-cell lymphoma of the bone marrow

  Masakatsu Hishizawa; Kohei Okamoto; Kazuhisa Chonabayashi; Hitomi Kaneko; Mitsumasa Watanabe; Mitsuru Tsudo

  British Journal of Haematology, Feb. 2007, Peer-reviewed

  
• [Successful treatment with cyclosporine of sodium valproate-induced pure red cell aplasia].

  Kanda J; Chonabayashi K; Watanabe M; Arima N; Tsudo M

  [Rinsho ketsueki] The Japanese journal of clinical hematology, Oct. 2005, Peer-reviewed

  
• Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane

  K Uemura; N Kitagawa; R Kohno; A Kuzuya; T Kageyama; K Chonabayashi; H Shibasaki; S Shimohama

  JOURNAL OF NEUROSCIENCE RESEARCH, Oct. 2003, Peer-reviewed

  

Misc.

• Single Cell Electrophysiological Analysis of iPS Cell-Derived Cardiomyocytes Generated from Long-QT Syndrome Patients Carrying a CALM2 Mutation Using a Membrane Potential Imaging System

  YAMAMOTO Yuta; MAKIYAMA Takeru; WURIYANGHAI Yimin; KOHJITANI Hirohiko; HIROSE Sayako; GAO Jingshan; KASHIWA Asami; HUANG Hai; ISHIKAWA Taisuke; OHNO Seiko; CHONABAYASHI Kazuhisa; SUDA Kenji; YOSHIDA Yoshinori; HORIE Minoru; MAKITA Naomasa; KIMURA Takeshi

  日本不整脈心電学会学術大会プログラム・抄録集(Web), 2019

  
• Elucidating the pathophysiology of AML with atypical 3q26 translocations using patient-derived iPSCs

  中村桃子; 中村桃子; 蝶名林和久; 蝶名林和久; 森本有紀; 森本有紀; 越智陽太郎; 越智陽太郎; 南谷泰仁; 北脇年雄; 菱澤方勝; 菱澤方勝; 小川誠司; 高折晃史; 吉田善紀

  日本血液学会学術集会抄録(Web), 2021

  
• ETNK1 mutations defines a subclass of der(1;7)(q10;p10) in myelodysplastic syndromes

  奥田瑠璃花; 南谷泰人; 越智陽太郎; 蝶名林和久; 蝶名林和久; 牧島秀樹; 吉里哲一; 永田安伸; 竹田淳恵; 吉田健一; 眞田昌; 眞田昌; 昆彩奈; 白石雄一; 宮野悟; 熱田由子; 笠原千嗣; 半田寛; 千葉滋; 大屋敷一馬; 吉田善紀; 小川誠司; 小川誠司; 小川誠司

  日本血液学会学術集会抄録(Web), 2021

  
• ETNK1変異の有無を特徴とするder(1;7)(q10;p10)を伴う骨髄異形成症候群

  奥田瑠璃花; 南谷泰仁; 越智陽太郎; 蝶名林和久; 蝶名林和久; 牧島秀樹; 永田安伸; 真田昌; 白石友一; 宮野悟; 宮野悟; 熱田由子; 笠原千嗣; 半田寛; 千葉滋; 大屋敷一馬; 小川誠司; 小川誠司; 小川誠司

  日本癌学会学術総会抄録集(Web), 2021

  
• 疾患iPS細胞を用いたX連鎖性鉄芽球性貧血の病態解明(Modeling X-linked sideroblastic anemia with patient-derived human induced pluripotent stem cells)

  森本 有紀; 蝶名林 和久; 川端 浩; 高折 晃史; 吉田 善紀

  臨床血液, Sep. 2018

  
• リプログラミング技術を用いた骨髄異形成症候群の腫瘍内遺伝的・機能的多様性の解明

  蝶名林 和久; 吉田 善紀; 高折 晃史

  臨床血液, Jul. 2017

  
• CALM遺伝子変異によるQT延長症候群の患者由来iPS細胞を用いた疾患モデルにおける変異アレル特異的ノックアウトによる治療的アプローチ

  山本雄大; 牧山武; 張田健志; 佐々木健一; 早野護; 西内英; ウリヤンハイ イミン; 糀谷泰彦; 廣瀬紗也子; チン カヨウ; 石川泰輔; 大野聖子; 蝶名林和久; 吉田善紀; 堀江稔; 蒔田直昌; 木村剛

  日本分子生物学会年会プログラム・要旨集(Web), 2016

  
• 血液・免疫疾患 6.リプログラミング技術を用いた骨髄異形成症候群の病態解明と新規治療の可能性

  蝶名林和久; 吉田善紀; 高折晃史

  遺伝子医学MOOK, 05 Feb. 2015

  
• 【iPS細胞を用いた難病研究-臨床病態解明と創薬に向けた研究の最新知見】 (第4章)血液・免疫疾患 リプログラミング技術を用いた骨髄異形成症候群の病態解明と新規治療の可能性

  蝶名林 和久; 吉田 善紀; 高折 晃史

  遺伝子医学MOOK, Feb. 2015

  
• 疾患特異的iPS細胞を活用した特発性造血障害の病態解析と新規治療法開発 骨髄異形成症候群に関わる研究開発

  蝶名林和久; 吉田善紀

  疾患特異的iPS細胞を活用した特発性造血障害の病態解析と新規治療法の開発 平成26年度 委託業務成果報告書, 2015

  
• ETV6/FLT3はマウス骨髄移植モデルにおいて骨髄増殖性疾患を誘導する(Efficient and rapid induction of myeloproliferative disorder by ETV6/FLT3 using a murine bone marrow transplant model)

  蝶名林 和久; 菱澤 方勝; 石川 隆之; 内山 卓

  日本癌学会総会記事, Aug. 2009

  
• 難治性白血病におけるHippo経路の破綻と治療抵抗性の分子機構

  堀利行; 河原真大; 蝶名林和久; 内山卓

  臨床血液, 30 Sep. 2008

  
• Hippo経路とDNA傷害シグナルの関係 Kpm/Lats2は白血病細胞の抗がん剤感受性に影響する(Relationship between the Hippo pathway and DNA damage signals: Kpm/Lats2 affects chemo-sensitivity of leukemic cells)

  河原 真大; 蝶名林 和久; 内山 卓; 岡 勉; スドール・マリウス; 堀 利行

  日本癌学会総会記事, Sep. 2008

  
• 血液内科病棟におけるカルバペネム系抗菌剤使用制限

  石上隆宏; 斉藤崇; 石川隆之; 井尾克宏; 松井道志; 蝶名林和久; 一戸辰夫; 山下浩平; 近藤忠一; 一山智; 内山卓

  臨床血液, 30 Sep. 2007

  
• 急性骨髄性白血病・ハイリスク骨髄異形成症候群に対する同種造血幹細胞移植の成績に急性GVHDが与える影響

  井尾克宏; 鎌田淳也; 一戸辰夫; 松井道志; 蝶名林和久; 石上隆宏; 菱澤方勝; 錦織桃子; 川端浩; 山下浩平; 近藤忠一; 高折晃史; 堀利行; 門脇則光; 石川隆之; 内山卓

  臨床血液, 30 Sep. 2007

  
• HTLV‐I陰性成熟T/NK細胞腫瘍に対する同種造血幹細胞移植

  蝶名林和久; 石川隆之; 一戸辰夫; 井尾克宏; 石上隆宏; 松井道志; 鷹尾珠美子; 近藤忠一; 山下浩平; 菱澤方勝; 錦織桃子; 川端浩; 高折晃史; 門脇則光; 堀利行; 内山卓

  臨床血液, 30 Sep. 2007

  
• 緩和な前処置を用いた同種造血幹細胞移植における幹細胞源としての骨髄と末梢血の比較

  松井道志; 諌田淳也; 一戸辰夫; 井尾克宏; 蝶名林和久; 石上隆宏; 菱澤方勝; 錦織桃子; 川端浩; 山下浩平; 近藤忠一; 高折晃史; 堀利行; 門脇則光; 石川隆之; 内山卓

  臨床血液, 30 Sep. 2007

  
• Successful treatment of pure red cell aplasia after major ABO-incompatible unrelated bone marrow transplantation for chronic myelocytic leukemia with plasma exchange

  CHONABAYASHI Kazuhisa; WATANABE Mitsumasa; KANDA Junya; ARIMA Nobuyoshi; TSUDO Mitsuru

  The Japanese Red Cross medical journal, 10 Jul. 2007

  
• 症例から学ぶピットフォール 代謝低下に起因する血中CEAの上昇

  蝶名林和久; 國立裕之

  内科, 01 Apr. 2007

  
• Refractory thrombotic thrombocytopenic purpura successfully treated with a combination of rituximab and vincristine

  KANEKO Hitomi; MATSUMOTO Masanori; OKAMOTO Kohei; CHYONABAYASHI Kazuhisa; HISHIZAWA Masakatsu; WATANABE Mitsumasa; FUJIMURA Yoshihiro; TSUDO Mitsuru

  臨床血液, 28 Feb. 2007

  
• 骨髄非破壊的同種造血幹細胞移植を行った末梢性T細胞リンパ腫の2例

  岡本浩平; 菱澤方勝; 西澤正俊; 蝶名林和久; 金子仁臣; 渡邊光正; 通堂満

  臨床血液, 30 Sep. 2006

  
• シクロスポリン投与により軽快したバルプロ酸ナトリウムによる赤芽球ろう

  諌田淳也; 蝶名林和久; 渡辺光正; 有馬靖佳; 通堂満

  臨床血液, 30 Oct. 2005

  
• シクロスポリン投与により軽快したバルプロ酸ナトリウムによる赤芽球癆

  諌田 淳也; 蝶名林 和久; 渡邊 光正; 有馬 靖佳; 通堂 満

  臨床血液, Oct. 2005

  
• Rituximabが著効したCD5陰性B-CLLに合併した赤芽球癆の1例

  渡邊 光正; 蝶名林 和久; 諌田 淳也; 有馬 靖佳; 通堂 満

  日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2005

  
• 非血縁者間骨髄移植後の赤芽球癆に対し血漿交換が奏効した慢性骨髄性白血病の一例

  蝶名林 和久; 渡邊 光正; 諌田 淳也; 有馬 靖佳; 通堂 満

  日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2005

  
• 非血縁者間骨髄移植後の赤芽球ろうに対し血しょう交換が奏効した慢性骨髄性白血病の一例

  蝶名林和久; 渡辺光正; 諌田淳也; 有馬靖佳; 通堂満

  臨床血液, 30 Aug. 2005

  
• Rituximabが著効したCD5陰性B‐CLLに合併した赤芽球ろうの1例

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  臨床血液, 30 Aug. 2005

  
• Lemierre症候群の1例

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  内科, 01 Aug. 2005

  
• 腰椎圧迫骨折,高カルシウム血症で発症した急性巨核芽球性白血病の2症例

  諌田 淳也; 蝶名林 和久; 渡邊 光正; 赤坂 浩司; 有馬 靖佳; 通堂 満

  日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2004

  
• R-CHOP療法が著効したB-PLLの1例

  渡邊 光正; 蝶名林 和久; 諫田 淳也; 赤坂 浩司; 有馬 靖佳; 通堂 満

  日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2004

  
• 腰椎圧迫骨折,高カルシウム血症で発症した急性巨核芽球性白血病の2症例

  諌田淳也; 蝶名林和久; 渡辺光正; 赤坂浩司; 有馬靖佳; 通堂満

  臨床血液, 30 Aug. 2004

  
• R‐CHOP療法が著効したB‐PLLの1例

  渡辺光正; 蝶名林和久; 諌田淳也; 赤坂浩司; 有馬靖佳; 通堂満

  臨床血液, 30 Aug. 2004

  
• MTX大量療法,自家末梢血幹細胞移植により完全寛解に至った脳原発および脳内再発悪性リンパ腫の2症例

  諌田淳也; 蝶名林和久; 渡辺光正; 赤坂浩司; 有馬靖佳; 通堂満

  日本リンパ網内系学会会誌, 10 Jun. 2004

  
• 古典的結節性多発動脈炎(PN)と鑑別を要した顕微鏡的多発血管炎(MPA)の一例

  金森弘志; 蝶名林和久; 松原雄; 長井幸二郎; 若月芳雄; 荒井秀典; 北徹; 深津敦司

  Pharma Medica, 10 Apr. 2003

  
• 抗好中球細胞質抗体(MPO‐ANCA)陽性の,古典的結節性多発動脈炎(PN)と考えられた症例

  蝶名林和久; 金森弘志; 若月芳雄; 田中誠; 堀内久徳; 深津敦司; 北徹

  日本老年医学会雑誌, 25 Jul. 2002

  
• Distinct ethnic, clinical, and genetic characteristics of der(1;7) in myelodysplastic syndromes.

  Rurika Okuda; Yasuhito Nannya; Yotaro Ochi; Kazuhisa Chonabayashi; Maria Creignou; Hideki Makishima; June Takeda; Ayana Kon; Satoru Miyano; Hiroshi Handa; Shigeru Chiba; Kazuma Ohyashiki; Torsten Haferlach; Eva Lindberg; Seishi Ogawa

  CANCER SCIENCE, Feb. 2021

  
• Der(1;7) 陽性骨髄異形成症候群における人種,臨床像,遺伝学的観点からみた特徴

  奥田瑠璃花; 南谷泰仁; 越智陽太郎; 蝶名林和久; 蝶名林和久; 牧島秀樹; 吉里哲一; 永田安伸; 竹田淳恵; 吉田健一; 真田昌; 真田昌; 昆彩奈; 白石友一; 宮野悟; 宮野悟; KERN Wolfgang; BAER Constance; NADARAJAH Niroshan; ALPERMANN Tamara; HAFERLACH Claudia; 熱田由子; 笠原千嗣; 半田寛; 千葉滋; 大屋敷一馬; HAFERLACH Torsten; 吉田善紀; 小川誠司; 小川誠司; 小川誠司

  日本血液学会学術集会抄録(Web), 2020

  
• KCNQ1 Channel Dysfunction in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying a CALM2-N98S Mutation Associated With Long QT Syndrome

  Yuta Yamamoto; Takeru M. Makiyama; Yimin Wuriyanghai; Hirohiko Kohjitani; Sayako Hirose; Jingshan Gao; Asami Kashiwa; Huang Hai; Takanori Aizawa; Tomohiko Imamura; Taisuke Ishikawa; Seiko Ohno; Kazuhisa Chonabayashi; Hideki Motomura; Yoshinori Yoshida; Minoru Horie; Naomasa Makita; Takeshi Kimura

  CIRCULATION, Nov. 2019

  
• Escape Hematopoiesis By HLA-B5401-Lacking Hematopoietic Stem Progenitor Cells in Male Patients with Acquired Aplastic Anemia

  Kohei Hosokawa; Mahmoud Ibrahim Elbadry; Hiroki Mizumaki; Luis Espinoza; Noriharu Nakagawa; Kazuhisa Chonabayashi; Yoshinori Yoshida; Takamasa Katagiri; Yoshitaka Zaimoku; Tatsuya Imi; Nguyen Thi Mai Anh; Yoichi Fujii; Seishi Ogawa; Katsuto Takenaka; Koichi Akashi; Shinji Nakao

  BLOOD, Nov. 2018

  
• I-cis-diltiazem rescues impaired calcium channel inactivation in an iPSC-model of CACNA1C-associated long-QT syndrome

  HARITA Takeshi; MAKIYAMA Takeru; TOYODA Futoshi; SASAKI Kenichi; NISHIUCHI Suguru; HAYANO Mamoru; YAMAMOTO Yuta; KOHJITANI Hirohiko; WURIYANGHAI Yimin; HIROSE Sayako; CHEN Jiarong; FUKUYAMA Megumi; CHONABAYASHI Kazuhisa; OHNO Seiko; YOSHIDA Yoshinori; UEYAMA Takeshi; SHIMIZU Akihiko; MATSUURA Hiroshi; HORIE Minoru; KIMURA Takeshi

  Journal of Physiological Sciences, 2017

  
• Ips Technology Revealed the Genetic and Functional Diversity Present in a Secondary AML Patient

  Kazuhisa Chonabayashi; Masahiro Kawahara; Akira Watanabe; Masahiro Nakamura; Masatoshi Nishizawa; Akifumi Takaori-Kondo; Shinya Yamanaka; Yoshinori Yoshida

  BLOOD, Dec. 2016

  
• l-cis Diltiazem Rescues Impaired Calcium Channel Inactivation in a Patient-specific Stem Cell Model of Long QT Syndrome with a CACNA1C Mutation

  HARITA Takeshi; MAKIYAMA Takeru; TOYODA Futoshi; SASAKI Kenichi; NISHIUCHI Suguru; HAYANO Mamoru; YAMAMOTO Yuta; KOHJITANI Hirohiko; WURIYANGHAI Yimin; HIROSE Sayako; CHEN Jiarong; CHONABAYASHI Kazuhisa; OHNO Seiko; YOSHIDA Yoshinori; UEYAMA Takeshi; SHIMIZU Akihiko; HORIE Minoru; KIMURA Takeshi

  日本不整脈心電学会学術大会プログラム・抄録集(Web), 2016

  
• Generation of Ips Cell-Derived Hematopoietic Progenitor Cells from Patients with Acquired Aplastic Anemia Harboring Copy Number Neutral Loss of Heterozygosity of the Short Arm of Chromosome 6

  Luis Espinoza; Yoshinori Yoshida; Kazuhisa Chonabayashi; Takamasa Katagiri; Yoshitaka Zaimoku; Shinji Nakao

  BLOOD, Dec. 2015

  
• Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Maturation Defect of Myelodysplastic Syndromes

  Kazuhisa Chonabayashi; Masahiro Kawahara; Keisuke Okita; Masatoshi Nishizawa; Norimitsu Kadowaki; Akifumi Takaori-Kondo; Shinya Yamanaka; Yoshinori Yoshida

  BLOOD, Dec. 2014

  
• iPS technology revealed the genetic and functional diversity present in a single MDS patient

  Chonabayashi K; Kawahara M; Watanabe A; Amano N; Okita K; Nishizawa M; Kadowaki N; Takaori-Kondo A; Yamanaka S; Yoshida Y

  臨床血液, Sep. 2014

  
• Search for pathogenesis of acquired myelodysplastic syndromes using reprogramming technology

  Chonabayashi K; Kawahara M; Watanabe A; Okita K; Nishizawa M; Kadowaki N; Takaori-Kondo A; Yamanaka S; Yoshida Y

  第75回日本血液学会学術集会, Oct. 2013

  
• Direct Binding of Grb2 Is Required for Efficient Induction of Myeloproliferative Disease in Mice by ETV6/FLT3

  Kazuhisa Chonabayashi; Masakatsu Hishizawa; Shin Kawamata; Masashi Matsui; Tatsuharu Ohno; Takayuki Ishikawa; Takashi Uchiyama

  BLOOD, Nov. 2009

  
• Kpm/Lats2 of the Hippo Pathway Is Linked to Chemo-Sensitivity of Leukemic Cells

  Masahiro Kawahara; Toshiyuki Hori; Kazuhisa Chonabayashi; Tsutomu Oka; Marius Sudol; Takashi Uchiyama

  BLOOD, Nov. 2008

  

Awards

• 16 Oct. 2015

  日本血液学会, 日本血液学会奨励賞

External funds: Kakenhi

• 非定型3q26転座型骨髄性腫瘍のEVI1エピジェネティック制御機構解明と治療応用

  Grant-in-Aid for Scientific Research (C)

  Basic Section 54010:Hematology and medical oncology-related

  Kyoto University

  蝶名林 和久

  From 01 Apr. 2021, To 31 Mar. 2024, Granted

  非定型3q26転座型骨髄性腫瘍;EVI1活性化;転写制御領域;疾患特異的iPS細胞;BET阻害剤;スーパーエンハンサー

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K08414/
• Reprogramming technology revealed the genetic and functional diversity present in an individual myelodysplastic syndrome patient

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Kazuhisa Chonabayashi

  From 01 Apr. 2016, To 31 Mar. 2019, Project Closed

  骨髄異形成症候群;二次性急性骨髄性白血病;リプログラミング;iPS細胞;腫瘍内多様性;新規治療薬

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K09847/
• Search for pathogenesis and novel therapeutics of acquired myelodysplastic syndromes using reprogramming technology

  Grant-in-Aid for Young Scientists (B)

  Kyoto University

  Kazuhisa Chonabayashi

  From 01 Apr. 2014, To 31 Mar. 2016, Project Closed

  骨髄異形成症候群;血液分化異常;リプログラミング;iPS細胞;病態解明;新規治療薬;MDS;造血前駆細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26860727/
• Elucidation of the regulatory mechanism of the SLF1/2-SMC5/6 pathway in hematopoiesis and its therapeutic application

  Grant-in-Aid for Scientific Research (C)

  Basic Section 54010:Hematology and medical oncology-related

  Kyoto University

  蝶名林 和久

  From 01 Apr. 2024, To 31 Mar. 2027, Granted

  SLF1/2-SMC5/6経路;Atelis症候群;遺伝性骨髄不全症候群;疾患特異的iPS細胞;骨髄性腫瘍

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K11514/