Basic Information

Faculty

• 医学部

Academic Degree

• M.D., Ph.D.(Kyoto University)

Academic Resume (Graduate Schools)

• Kyoto University, Graduate School of Medicine, Cardiovascular Medicine, 修了

Academic Resume (Undergraduate School/Majors)

• Kyoto University, School of Medicine, Medicine, 卒業

Language of Instruction

• English

ID,URL

• J-Global ID

  201401043600576185

Website(s) (URL(s))

• http://kyoto-u-cardio.jp/kisokenkyu/metabolic/

researchmap URL

• https://researchmap.jp/7000008602

Research

Research Topics, Overview of the research

• Research Topics

  heart failure, atherosclerosis, ischemic heart disease, non-coding RNA

• Overview of the research

  We are conducting clinical relevant researches using clinical samples, genetically engineered mice, and iPS cells to study the mechanisms of the development of heart failure and the roles of non-coding RNAs in cardiovascular diseases.

Research Areas

• Life sciences, Cardiology

Papers

• Aspirin versus Clopidogrel Monotherapy After Percutaneous Coronary Intervention: 1-Year Follow-up of the STOPDAPT-3 Trial.

  Hirotoshi Watanabe; Masahiro Natsuaki; Takeshi Morimoto; Ko Yamamoto; Yuki Obayashi; Ryusuke Nishikawa; Tomoya Kimura; Kenji Ando; Takenori Domei; Satoru Suwa; Manabu Ogita; Tsuyoshi Isawa; Hiroyuki Takenaka; Takashi Yamamoto; Tetsuya Ishikawa; Itaru Hisauchi; Kohei Wakabayashi; Yuko Onishi; Kiyoshi Hibi; Kazuya Kawai; Ruka Yoshida; Hiroshi Suzuki; Gaku Nakazawa; Takanori Kusuyama; Itsuro Morishima; Koh Ono; Takeshi Kimura

  European heart journal, 31 Aug. 2024

  
• Temporal Changes in Long-Term Outcomes of Venous Thromboembolism From the Warfarin Era to the Direct Oral Anticoagulant Era.

  Kazuhisa Kaneda; Yugo Yamashita; Takeshi Morimoto; Ryuki Chatani; Yuji Nishimoto; Nobutaka Ikeda; Yohei Kobayashi; Satoshi Ikeda; Kitae Kim; Moriaki Inoko; Toru Takase; Shuhei Tsuji; Maki Oi; Takuma Takada; Kazunori Otsui; Jiro Sakamoto; Yoshito Ogihara; Takeshi Inoue; Shunsuke Usami; Po-Min Chen; Kiyonori Togi; Norimichi Koitabashi; Seiichi Hiramori; Kosuke Doi; Hiroshi Mabuchi; Yoshiaki Tsuyuki; Koichiro Murata; Kensuke Takabayashi; Hisato Nakai; Daisuke Sueta; Wataru Shioyama; Tomohiro Dohke; Ryusuke Nishikawa; Koh Ono; Takeshi Kimura

  Journal of the American Heart Association, 06 Aug. 2024

  
• Statins use and recurrent venous thromboembolism in the direct oral anticoagulant era: insight from the COMMAND VTE Registry-2.

  Hiroshi Mabuchi; Ryusuke Nishikawa; Yugo Yamashita; Takeshi Morimoto; Ryuki Chatani; Kazuhisa Kaneda; Yuji Nishimoto; Nobutaka Ikeda; Yohei Kobayashi; Satoshi Ikeda; Kitae Kim; Moriaki Inoko; Toru Takase; Shuhei Tsuji; Maki Oi; Takuma Takada; Kazunori Otsui; Jiro Sakamoto; Yoshito Ogihara; Takeshi Inoue; Shunsuke Usami; Po-Min Chen; Kiyonori Togi; Norimichi Koitabashi; Seiichi Hiramori; Kosuke Doi; Yoshiaki Tsuyuki; Koichiro Murata; Kensuke Takabayashi; Hisato Nakai; Daisuke Sueta; Wataru Shioyama; Tomohiro Dohke; Koh Ono; Yoshihisa Nakagawa; Takeshi Kimura

  Journal of thrombosis and thrombolysis, Aug. 2024

  
• Efficacy and safety of Saireito (TJ-114) in patients with atrial fibrillation undergoing catheter ablation procedures: A randomized pilot study.

  Tetsuma Kawaji; Satoshi Shizuta; Hidenori Yaku; Kazuhisa Kaneda; Fumiya Yoneda; Shushi Nishiwaki; Munekazu Tanaka; Takanori Aizawa; Shun Hojo; Kenji Nakatsuma; Masashi Kato; Takafumi Yokomatsu; Shinji Miki; Koh Ono; Takeshi Kimura

  PloS one, 2024

  
• Prevalence and characteristics of atrioventricular nodal reentrant tachycardia with a bystander concealed nodoventricular/nodofascicular pathway.

  Shushi Nishiwaki; Satoshi Shizuta; Tomoyuki Inoue; Akifumi Morinaga; Fumiya Yoneda; Munekazu Tanaka; Takanori Aizawa; Hirohiko Kohjitani; Koh Ono

  Heart rhythm, 26 Jun. 2024

  
• Initial hemodynamic status and Acute Mortality in Cancer patients with Acute Pulmonary Embolism: from the COMMAND VTE Registry

  Wei Xiong; Yugo Yamashita; Takeshi Morimoto; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Yuji Nishimoto; Jiro Sakamoto; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Takao Kato; Koh Ono; Takeshi Kimura

  Journal of Thrombosis and Thrombolysis, 09 Jul. 2024

  
• An Aspirin-Free Strategy for Immediate Treatment Following Complex Percutaneous Coronary Intervention.

  Ko Yamamoto; Masahiro Natsuaki; Hirotoshi Watanabe; Takeshi Morimoto; Yuki Obayashi; Ryusuke Nishikawa; Kenji Ando; Satoru Suwa; Tsuyoshi Isawa; Hiroyuki Takenaka; Tetsuya Ishikawa; Toshihiro Tamura; Kando Kawahatsu; Fujio Hayashi; Masaharu Akao; Takeshi Serikawa; Hiroyoshi Mori; Takayuki Kawamura; Arata Hagikura; Naoki Shibata; Koh Ono; Takeshi Kimura

  JACC. Cardiovascular interventions, 13 May 2024

  
• Aspirin-free strategy for percutaneous coronary intervention in acute coronary syndrome based on the subtypes of acute coronary syndrome and high bleeding risk: the STOPDAPT-3 trial.

  Yuki Obayashi; Masahiro Natsuaki; Hirotoshi Watanabe; Takeshi Morimoto; Ko Yamamoto; Ryusuke Nishikawa; Kenji Ando; Satoru Suwa; Tsuyoshi Isawa; Hiroyuki Takenaka; Tetsuya Ishikawa; Hideo Tokuyama; Hiroki Sakamoto; Takanari Fujita; Mamoru Nanasato; Hideki Okayama; Tenjin Nishikura; Hidekuni Kirigaya; Koji Nishida; Koh Ono; Takeshi Kimura

  European heart journal. Cardiovascular pharmacotherapy, 29 Jan. 2024

  
• KUS121, a VCP modulator, has an ameliorating effect on acute and chronic heart failure without calcium loading via maintenance of intracellular ATP levels

  Shuhei Tsuji; Chiharu Otani; Takahiro Horie; Shin Watanabe; Osamu Baba; Naoya Sowa; Yuya Ide; Asami Kashiwa; Takeru Makiyama; Hirohiko Imai; Yasuhiro Nakashima; Tomohiro Yamasaki; Sijia Xu; Kazuki Matsushita; Keita Suzuki; Fuquan Zou; Eitaro Kume; Koji Hasegawa; Takeshi Kimura; Akira Kakizuka; Koh Ono

  Biomedicine & Pharmacotherapy, Jan. 2024

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• Prognostic impact of catheter ablation in patients with asymptomatic atrial fibrillation

  Tetsuma Kawaji; Satoshi Shizuta; Munekazu Tanaka; Shushi Nishiwaki; Takanori Aizawa; Shintaro Yamagami; Akihiro Komasa; Takashi Yoshizawa; Masashi Kato; Takafumi Yokomatsu; Shinji Miki; Koh Ono; Takeshi Kimura

  PLOS ONE, 15 Dec. 2022

  
• Insight from the microelectrodes in case of two different types of premature ventricular contractions originating from left ventricular summit.

  Shushi Nishiwaki; Satoshi Shizuta; Hirohiko Kohjitani; Koh Ono

  Indian pacing and electrophysiology journal, 08 May 2024

  
• Concomitant Mitral Regurgitation in Severe Aortic Stenosis - Insights From the CURRENT AS Registry-2.

  Yuki Obayashi; Yasuaki Takeji; Tomohiko Taniguchi; Takeshi Morimoto; Shinichi Shirai; Takeshi Kitai; Hiroyuki Tabata; Nobuhisa Ohno; Ryosuke Murai; Kohei Osakada; Koichiro Murata; Masanao Nakai; Hiroshi Tsuneyoshi; Tomohisa Tada; Masashi Amano; Shin Watanabe; Hiroki Shiomi; Hirotoshi Watanabe; Yusuke Yoshikawa; Ryusuke Nishikawa; Ko Yamamoto; Mamoru Toyofuku; Shojiro Tatsushima; Norio Kanamori; Makoto Miyake; Hiroyuki Nakayama; Kazuya Nagao; Masayasu Izuhara; Kenji Nakatsuma; Moriaki Inoko; Takanari Fujita; Masahiro Kimura; Mitsuru Ishii; Shunsuke Usami; Fumiko Nakazeki; Kiyonori Togi; Yasutaka Inuzuka; Kenji Ando; Tatsuhiko Komiya; Koh Ono; Kenji Minatoya; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 09 May 2024

  
• CRISPR-Cas9-guided amplification-free genomic diagnosis for familial hypercholesterolemia using nanopore sequencing.

  Sijia Xu; Hiroki Shiomi; Yugo Yamashita; Satoshi Koyama; Takahiro Horie; Osamu Baba; Masahiro Kimura; Yasuhiro Nakashima; Naoya Sowa; Koji Hasegawa; Ayako Suzuki; Yutaka Suzuki; Takeshi Kimura; Koh Ono

  PloS one, 2024

  
• Development of interpretable machine learning models to predict in-hospital prognosis of acute heart failure patients.

  Munekazu Tanaka; Hirohiko Kohjitani; Erika Yamamoto; Takeshi Morimoto; Takao Kato; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yuta Seko; Masayuki Shiba; Yusuke Yoshikawa; Yugo Yamashita; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Yasushi Okuno; Takeshi Kimura; Koh Ono

  ESC heart failure, 15 May 2024

  
• Who Requires Longer-term Anticoagulation Therapy for Venous Thromboembolism from the Perspective of Precision Medicine?

  Shinya Ikeda; Yugo Yamashita; Koh Ono

  European heart journal. Cardiovascular pharmacotherapy, 30 Apr. 2024

  
• Edoxaban for 12 Versus 3 Months in Cancer-associated Isolated Distal Deep Vein Thrombosis According to Different Doses: Insights from the ONCO DVT study.

  Ryuki Chatani; Yugo Yamashita; Takeshi Morimoto; Nao Muraoka; Michihisa Umetsu; Yuji Nishimoto; Takuma Takada; Yoshito Ogihara; Tatsuya Nishikawa; Nobutaka Ikeda; Kazunori Otsui; Daisuke Sueta; Yukari Tsubata; Masaaki Shoji; Ayumi Shikama; Yutaka Hosoi; Yasuhiro Tanabe; Kengo Tsukahara; Naohiko Nakanishi; Kitae Kim; Satoshi Ikeda; Kazunori Mushiake; Kazushige Kadota; Koh Ono; Takeshi Kimura

  European heart journal. Cardiovascular pharmacotherapy, 22 Apr. 2024

  
• Subclass phenotypes in patients with unprovoked venous thromboembolisms using a latent class analysis

  Shinya Ikeda; Yugo Yamashita; Takeshi Morimoto; Ryuki Chatani; Kazuhisa Kaneda; Yuji Nishimoto; Nobutaka Ikeda; Yohei Kobayashi; Satoshi Ikeda; Kitae Kim; Moriaki Inoko; Toru Takase; Shuhei Tsuji; Maki Oi; Takuma Takada; Kazunori Otsui; Jiro Sakamoto; Yoshito Ogihara; Takeshi Inoue; Shunsuke Usami; Po-Min Chen; Kiyonori Togi; Norimichi Koitabashi; Seiichi Hiramori; Kosuke Doi; Hiroshi Mabuchi; Yoshiaki Tsuyuki; Koichiro Murata; Kensuke Takabayashi; Hisato Nakai; Daisuke Sueta; Wataru Shioyama; Tomohiro Dohke; Ryusuke Nishikawa; Koh Ono; Takeshi Kimura

  Thrombosis Research, Jun. 2024

  
• Home Treatment for Active Cancer Patients With Low-Risk Pulmonary Embolism ― A Predetermined Companion Report From the ONCO PE Trial ―

  Ryuki Chatani; Yugo Yamashita; Takeshi Morimoto; Nao Muraoka; Wataru Shioyama; Tatsuhiro Shibata; Yuji Nishimoto; Yoshito Ogihara; Kosuke Doi; Maki Oi; Taro Shiga; Daisuke Sueta; Kitae Kim; Yasuhiro Tanabe; Norimichi Koitabashi; Takuma Takada; Satoshi Ikeda; Hitoshi Nakagawa; Takayuki Mitsuhashi; Masaaki Shoji; Jiro Sakamoto; Shinji Hisatake; Yutaka Ogino; Masashi Fujita; Naohiko Nakanishi; Tomohiro Dohke; Seiichi Hiramori; Ryuzo Nawada; Kazuhisa Kaneda; Kazunori Mushiake; Hiromi Yamamoto; Kazushige Kadota; Koh Ono; Takeshi Kimura

  Circulation Journal, 08 Mar. 2024

  
• Erratum to 'SYNTAX Score and 1-Year Outcomes in the OPTIVUS-Complex PCI Study Multivessel Cohort' [American Journal of Cardiology (2023) 431-441].

  Masaomi Gohbara; Kiyoshi Hibi; Takeshi Morimoto; Hidekuni Kirigaya; Ko Yamamoto; Koh Ono; Hiroki Shiomi; Masanobu Ohya; Kyohei Yamaji; Hiroki Watanabe; Tetsuya Amano; Yoshihiro Morino; Kensuke Takagi; Junko Honye; Hitoshi Matsuo; Mitsuru Abe; Kazushige Kadota; Kenji Ando; Kouichi Nakao; Shinjo Sonoda; Satoru Suwa; Kazuya Kawai; Ken Kozuma; Yoshihisa Nakagawa; Yuji Ikari; Mamoru Nanasato; Keiichi Hanaoka; Kengo Tanabe; Yoshiki Hata; Takashi Akasaka; Takeshi Kimura

  The American journal of cardiology, 15 Jan. 2024

  
• Subclinical myocardial damage after anthracycline chemotherapy in Japanese patients with breast Cancer

  Kenji Nakatsuma; Neiko Ozasa; Mikiko Ohno; Hiroshi Ishiguro; Manabu Minami; Eiichiro Nishi; Masakazu Toi; Koh Ono; Takeshi Kimura

  Journal of Cardiology, Mar. 2024

  
• Col1α2-Cre-mediated recombination occurs in various cell types due to Cre expression in epiblasts.

  Yuzuru Matsumoto; Shinya Ikeda; Takeshi Kimura; Koh Ono; Noboru Ashida

  Scientific reports, 18 Dec. 2023

  
• An Aspirin-Free Versus Dual Antiplatelet Strategy for Coronary Stenting: STOPDAPT-3 Randomized Trial.

  Masahiro Natsuaki; Hirotoshi Watanabe; Takeshi Morimoto; Ko Yamamoto; Yuki Obayashi; Ryusuke Nishikawa; Kenji Ando; Takenori Domei; Satoru Suwa; Manabu Ogita; Tsuyoshi Isawa; Hiroyuki Takenaka; Takashi Yamamoto; Tetsuya Ishikawa; Itaru Hisauchi; Kohei Wakabayashi; Yuko Onishi; Kiyoshi Hibi; Kazuya Kawai; Ruka Yoshida; Hiroshi Suzuki; Gaku Nakazawa; Takanori Kusuyama; Itsuro Morishima; Koh Ono; Takeshi Kimura

  Circulation, 20 Feb. 2024

  
• Radiofrequency Catheter Ablation for Atrial Fibrillation Patients on Hemodialysis (From the Kansai Plus Atrial Fibrillation Registry) - Clinical Impact of Early Recurrence.

  Naoaki Onishi; Kazuaki Kaitani; Yoshihisa Nakagawa; Atsushi Kobori; Koichi Inoue; Toshiya Kurotobi; Itsuro Morishima; Yumie Matsui; Hirosuke Yamaji; Yuko Nakazawa; Kengo Kusano; Yukiko Shimizu; Koji Hanazawa; Toshihiro Tamura; Chisato Izumi; Takeshi Morimoto; Koh Ono; Takeshi Kimura; Satoshi Shizuta

  Circulation journal : official journal of the Japanese Circulation Society, 11 Jan. 2024

  
• Difference between Japanese and White patients with acute pulmonary embolism.

  Yugo Yamashita; Behnood Bikdeli; Manuel Monreal; Takeshi Morimoto; Takao Kato; Koh Ono; Cristina de Ancos; Juan J López-Núñez; Andrei Braester; Meritxell Mellado; Takeshi Kimura

  Thrombosis research, Aug. 2021

  
• Severity of pulmonary embolism at initial diagnosis and long-term clinical outcomes: From the COMMAND VTE Registry.

  Yugo Yamashita; Takeshi Morimoto; Kazushige Kadota; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Moriaki Inoko; Tomohisa Tada; Toshiaki Izumi; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Yuji Nishimoto; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Takao Kato; Koh Ono; Takeshi Kimura

  International journal of cardiology, 15 Nov. 2021

  
• Clinical Characteristics and Outcomes of Patients With Venous Thromboembolism Receiving Edoxaban in the Real World

  Yugo Yamashita; Toshiki Fukasawa; Chikashi Takeda; Masato Takeuchi; Koh Ono; Koji Kawakami

  Circulation Journal, 23 Dec. 2023

  
• Application of the RIETE score to identify low-risk patients with pulmonary embolism: From the COMMAND VTE Registry.

  Yuta Tsujisaka; Yugo Yamashita; Takeshi Morimoto; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Yuji Nishimoto; Jiro Sakamoto; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Takao Kato; Koh Ono; Takeshi Kimura

  Thrombosis research, Dec. 2023

  
• SGLT2 inhibitors in acute myocardial infarction: what can we learn from the DAPA-MI trial? More news from AHA.

  Eri Toda Kato; Koh Ono; Basil S Lewis

  European heart journal. Cardiovascular pharmacotherapy, 07 Dec. 2023

  
• Single-Session Versus Staged Multivessel Optimal IVUS-Guided PCI in Patients With CCS or NSTE-ACS

  Ko Yamamoto; Hiroki Shiomi; Takeshi Morimoto; Akiyoshi Miyazawa; Hiroki Watanabe; Sunao Nakamura; Satoru Suwa; Takenori Domei; Koh Ono; Hiroki Sakamoto; Masataka Shigetoshi; Ryoji Taniguchi; Hideki Okayama; Toshiaki Toyota; Takafumi Yokomatsu; Masahiro Muto; Ren Kawaguchi; Koichi Kishi; Mitsuyoshi Hadase; Tsutomu Fujita; Yasunori Nishida; Masami Nishino; Hiromasa Otake; Masahiro Natsuaki; Hirotoshi Watanabe; Nobuhiro Suematsu; Kengo Tanabe; Mitsuru Abe; Kiyoshi Hibi; Kazushige Kadota; Kenji Ando; Takeshi Kimura

  JACC: Asia, Aug. 2023

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• Dual Antiplatelet Therapy Duration After Multivessel Optimal Intravascular Ultrasound-Guided Percutaneous Coronary Intervention

  Ko Yamamoto; Hiroki Shiomi; Takeshi Morimoto; Akiyoshi Miyazawa; Hiroki Watanabe; Sunao Nakamura; Satoru Suwa; Takenori Domei; Koh Ono; Hiroki Sakamoto; Masataka Shigetoshi; Ryoji Taniguchi; Hideki Okayama; Takafumi Yokomatsu; Masahiro Muto; Ren Kawaguchi; Koichi Kishi; Mitsuyoshi Hadase; Tsutomu Fujita; Yasunori Nishida; Masami Nishino; Hiromasa Otake; Masahiro Natsuaki; Hirotoshi Watanabe; Nobuhiro Suematsu; Kengo Tanabe; Mitsuru Abe; Kiyoshi Hibi; Kazushige Kadota; Kenji Ando; Takeshi Kimura

  Circulation Journal, 25 Oct. 2023

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• SYNTAX Score and 1-Year Outcomes in the OPTIVUS-Complex PCI Study Multivessel Cohort

  Masaomi Gohbara; Kiyoshi Hibi; Takeshi Morimoto; Hidekuni Kirigaya; Ko Yamamoto; Koh Ono; Hiroki Shiomi; Masanobu Ohya; Kyohei Yamaji; Hiroki Watanabe; Tetsuya Amano; Yoshihiro Morino; Kensuke Takagi; Junko Honye; Hitoshi Matsuo; Mitsuru Abe; Kazushige Kadota; Kenji Ando; Kouichi Nakao; Shinjo Sonoda; Satoru Suwa; Kazuya Kawai; Ken Kozuma; Yoshihisa Nakagawa; Yuji Ikari; Mamoru Nanasato; Keiichi Hanaoka; Kengo Tanabe; Yoshiki Hata; Takashi Akasaka; Takeshi Kimura

  The American Journal of Cardiology, Oct. 2023

  
• Clopidogrel versus Aspirin Monotherapy Beyond 1 Year After PCI: STOPDAPT-2 5-Year Results

  Hirotoshi Watanabe; Takeshi Morimoto; Masahiro Natsuaki; Ko Yamamoto; Yuki Obayashi; Ryusuke Nishikawa; Kenji Ando; Koh Ono; Kazushige Kadota; Satoru Suwa; Itsuro Morishima; Ruka Yoshida; Yoshiki Hata; Masaharu Akao; Masahiro Yagi; Nobuhiro Suematsu; Yoshihiro Morino; Takafumi Yokomatsu; Itaru Takamisawa; Toshiyuki Noda; Masayuki Doi; Hideki Okayama; Yuichi Nakamura; Kiyoshi Hibi; Hiroki Sakamoto; Teruo Noguchi; Takeshi Kimura

  Journal of the American College of Cardiology, Oct. 2023

  
• Tricuspid regurgitation in elderly patients with acute heart failure: insights from the KCHF registry.

  Yuki Obayashi; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yuta Seko; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Neiko Ozasa; Takeshi Kimura

  ESC heart failure, 29 Mar. 2023

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• Successful cardiac synchronization therapy device upgrade using an active fixation quadripolar pacing lead in a patients with persistent left superior vena cava and absent right superior vena cava.

  Shushi Nishiwaki; Satoshi Shizuta; Munekazu Tanaka; Hirohiko Kohjitani; Koh Ono

  Journal of arrhythmia, Oct. 2023

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• Appetite loss at discharge from acute decompensated heart failure: Observation from KCHF registry.

  Erika Yamamoto; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mitsunori Kawato; Yuta Seko; Masayuki Shiba; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura

  PloS one, 2022

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• Biodegradable or durable polymer drug-eluting stents in patients with coronary artery disease: ten-year outcomes of the randomised NEXT Trial

  Masahiro Natsuaki; Hirotoshi Watanabe; Takeshi Morimoto; Ken Kozuma; Kazushige Kadota; Toshiya Muramatsu; Yoshihisa Nakagawa; Takashi Akasaka; Keiichi Igarashi Hanaoka; Kengo Tanabe; Yoshihiro Morino; Tetsuya Ishikawa; Harumi Katoh; Hideo Nishikawa; Toshihiro Tamura; Koh Ono; Ko Yamamoto; Takayuki Ishihara; Mitsuru Abe; Ryoji Taniguchi; Yuji Ikari; Kozo Okada; Takeshi Kimura

  EuroIntervention, Aug. 2023

  
• Sex Differences in the Japanese Circulation Society Guideline Writing Committee Authorship Between 2008 and 2022.

  Yugo Yamashita; Atsuko Nakayama; Maki Oi; Sachiko Sugioka; Yukiko Nakano; Misaki Naka; Sara Yasuda; Mei Onishi; Erika Yamamoto; Koh Ono

  Circulation. Cardiovascular quality and outcomes, Jun. 2023

  
• Age and long-term outcomes of patients with venous thromboembolism: From the COMMAND VTE Registry.

  Kotaro Takahashi; Yugo Yamashita; Takeshi Morimoto; Tomohisa Tada; Hiroki Sakamoto; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Yuji Nishimoto; Jiro Sakamoto; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Takao Kato; Koh Ono; Takeshi Kimura

  International journal of cardiology, May 2023, Peer-reviewed

  
• Target Lesion Revascularization After Intravascular Ultrasound-Guided Percutaneous Coronary Intervention.

  Ko Yamamoto; Hiroki Shiomi; Takeshi Morimoto; Akiyoshi Miyazawa; Hiroki Watanabe; Masahiro Natsuaki; Hirotoshi Watanabe; Kyohei Yamaji; Masanobu Ohya; Sunao Nakamura; Satoru Mitomo; Satoru Suwa; Takenori Domei; Shojiro Tatsushima; Koh Ono; Hiroki Sakamoto; Kiyotaka Shimamura; Masataka Shigetoshi; Ryoji Taniguchi; Yuji Nishimoto; Hideki Okayama; Kensho Matsuda; Takafumi Yokomatsu; Masahiro Muto; Ren Kawaguchi; Koichi Kishi; Mitsuyoshi Hadase; Tsutomu Fujita; Yasunori Nishida; Masami Nishino; Hiromasa Otake; Nobuhiro Suematsu; Tsuneki Ajimi; Kengo Tanabe; Mitsuru Abe; Kiyoshi Hibi; Kazushige Kadota; Kenji Ando; Takeshi Kimura

  Circulation. Cardiovascular interventions, May 2023

  
• Optimal Intravascular Ultrasound-Guided Percutaneous Coronary Intervention in Patients With Multivessel Disease.

  Ko Yamamoto; Hiroki Shiomi; Takeshi Morimoto; Hiroki Watanabe; Akiyoshi Miyazawa; Kyohei Yamaji; Masanobu Ohya; Sunao Nakamura; Satoru Mitomo; Satoru Suwa; Takenori Domei; Shojiro Tatsushima; Koh Ono; Hiroki Sakamoto; Kiyotaka Shimamura; Masataka Shigetoshi; Ryoji Taniguchi; Yuji Nishimoto; Hideki Okayama; Kensho Matsuda; Takafumi Yokomatsu; Masahiro Muto; Ren Kawaguchi; Koichi Kishi; Mitsuyoshi Hadase; Tsutomu Fujita; Yasunori Nishida; Masami Nishino; Hiromasa Otake; Kengo Tanabe; Mitsuru Abe; Kiyoshi Hibi; Kazushige Kadota; Kenji Ando; Takeshi Kimura

  JACC. Asia, Apr. 2023

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• Comparison of the OPTIVUS-Complex PCI Multivessel Cohort With the Historical CREDO-Kyoto Registry Cohort-3.

  Ko Yamamoto; Hiroki Shiomi; Takeshi Morimoto; Hiroki Watanabe; Akiyoshi Miyazawa; Kyohei Yamaji; Masanobu Ohya; Sunao Nakamura; Satoru Mitomo; Satoru Suwa; Takenori Domei; Shojiro Tatsushima; Koh Ono; Hiroki Sakamoto; Kiyotaka Shimamura; Masataka Shigetoshi; Ryoji Taniguchi; Yuji Nishimoto; Hideki Okayama; Kensho Matsuda; Kenji Nakatsuma; Yohei Takayama; Jun Kuribara; Hidekuni Kirigaya; Kohei Yoneda; Yuta Imai; Umihiko Kaneko; Hiroshi Ueda; Kota Komiyama; Naotaka Okamoto; Satoru Sasaki; Kengo Tanabe; Mitsuru Abe; Kiyoshi Hibi; Kazushige Kadota; Kenji Ando; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 11 Mar. 2023

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• Inhibition of microRNA-33b in humanized mice ameliorates nonalcoholic steatohepatitis.

  Sawa Miyagawa; Takahiro Horie; Tomohiro Nishino; Satoshi Koyama; Toshimitsu Watanabe; Osamu Baba; Tomohiro Yamasaki; Naoya Sowa; Chiharu Otani; Kazuki Matsushita; Hidenori Kojima; Masahiro Kimura; Yasuhiro Nakashima; Satoshi Obika; Yuuya Kasahara; Jun Kotera; Kozo Oka; Ryo Fujita; Takashi Sasaki; Akihiro Takemiya; Koji Hasegawa; Takeshi Kimura; Koh Ono

  Life science alliance, Aug. 2023

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• Soluble Vascular Endothelial Growth Factor Receptor-2 as a Predictor of the New Onset of Diabetes Following Smoking Cessation

  Wada Hiromichi; Ura Suichi; Satoh-Asahara Noriko; Akao Masaharu; Abe Mitsuru; Morimoto Tatsuya; Ono Koh; Shimatsu Akira; Takahashi Yuko; Hasegawa Koji

  CIRCULATION, 26 Nov. 2013, Peer-reviewed

  
• Prognostic Value of the Severity of Clinical Congestion in Patients Hospitalized for Decompensated Heart Failure: Findings From the Japanese KCHF Registry.

  Kenji Aida; Kazuya Nagao; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Tsukasa Inada; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Neiko Ozasa; Takeshi Kimura

  Journal of cardiac failure, 21 Jan. 2023

  
• Clinical characteristics, management strategies and outcomes of patients with recurrent venous thromboembolism in the real world.

  Yugo Yamashita; Takeshi Morimoto; Kazushige Kadota; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Moriaki Inoko; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Yuji Nishimoto; Jiro Sakamoto; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Takao Kato; Koh Ono; Takeshi Kimura

  Scientific reports, Dec. 2022, Peer-reviewed

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• Impact of Heart Rate at Diagnosis on Clinical Outcomes in Patients With Acute Pulmonary Embolism.

  Yugo Yamashita; Takeshi Morimoto; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Yuji Nishimoto; Jiro Sakamoto; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Takao Kato; Koh Ono; Takeshi Kimura

  The American journal of cardiology, Nov. 2022, Peer-reviewed

  
• Impact of chronic lung disease on long-term clinical outcomes in patients with venous thromboembolism: From the COMMAND VTE registry.

  Shinya Ikeda; Yugo Yamashita; Takeshi Morimoto; Koh Ono; Takeshi Kimura

  European journal of internal medicine, 05 Nov. 2022

  
• Causes of long-term mortality in patients with venous thromboembolism in the real world: From the COMMAND VTE registry.

  Yugo Yamashita; Takeshi Morimoto; Kazushige Kadota; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Moriaki Inoko; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Yuji Nishimoto; Jiro Sakamoto; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Takao Kato; Koh Ono; Takeshi Kimura

  Thrombosis research, Nov. 2022

  
• Anticoagulation strategies and clinical outcomes after bleeding events during anticoagulation therapy for venous thromboembolism in the practice-based Japanese registry.

  Yugo Yamashita; Takeshi Morimoto; Frederikus A Klok; Stefano Barco; Yuji Nishimoto; Takao Kato; Koh Ono; Takeshi Kimura

  Journal of thrombosis and thrombolysis, Oct. 2022

  
• Optimal quality of vitamin K antagonist therapy in Japanese patients with venous thromboembolism.

  Seiichi Hiramori; Yugo Yamashita; Takeshi Morimoto; Kazushige Kadota; Toru Takase; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Moriaki Inoko; Tomohisa Tada; Toshiaki Izumi; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Yuji Nishimoto; Tomoki Sasa; Mitsuo Matsuda; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yoshihisa Nakagawa; Takao Kato; Koh Ono; Kenji Ando; Takeshi Kimura

  Journal of cardiology, Nov. 2022, Peer-reviewed

  
• Public assistance in patients with acute heart failure: a report from the KCHF registry.

  Yuji Nishimoto; Takao Kato; Takeshi Morimoto; Ryoji Taniguchi; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Koichiro Kuwahara; Neiko Ozasa; Yukihito Sato; Takeshi Kimura

  ESC heart failure, 15 Mar. 2022, Peer-reviewed

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• Current use of inotropes according to initial blood pressure and peripheral perfusion in the treatment of congestive heart failure: findings from a multicentre observational study.

  Kazuya Nagao; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Tsukasa Inada; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Neiko Ozasa; Takeshi Kimura

  BMJ open, 20 Jan. 2022, Peer-reviewed

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• Correction: Matched comparison of catheter ablation versus conservative management for atrial fibrillation.

  Tetsuma Kawaji; Satoshi Shizuta; Kyohei Yamaji; Munekazu Tanaka; Kazuki Kitano; Takanori Aizawa; Shintaro Yamagami; Akihiro Komasa; Takashi Yoshizawa; Masashi Kato; Takafumi Yokomatsu; Shinji Miki; Koh Ono; Takeshi Morimoto; Takeshi Kimura

  Heart and vessels, 30 Jul. 2022

  
• is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.

  Fumiko Nakazeki; Itaru Tsuge; Takahiro Horie; Keiko Imamura; Kayoko Tsukita; Akitsu Hotta; Osamu Baba; Yasuhide Kuwabara; Tomohiro Nishino; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Shuhei Tsuji; Motoko Naitoh; Shigehiko Suzuki; Yuishin Izumi; Toshitaka Kawarai; Ryuji Kaji; Takeshi Kimura; Haruhisa Inoue; Koh Ono

  Clinical Science, 22 Feb. 2019, Peer-reviewed

  
• Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways

  Tomohiro Yamasaki; Takahiro Horie; Satoshi Koyama; Tetsushi Nakao; Osamu Baba; Masahiro Kimura; Naoya Sowa; Kazuhisa Sakamoto; Kazuhiro Yamazaki; Satoshi Obika; Yuuya Kasahara; Jun Kotera; Kozo Oka; Ryo Fujita; Takashi Sasaki; Akihiro Takemiya; Koji Hasegawa; Kenji Minatoya; Takeshi Kimura; Koh Ono

  Scientific Reports, Dec. 2022

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• Heme oxygenase-1遺伝子のプロモータ変異は日本人における虚血性心疾患の発生を減少させるかもしれない(A promoter variant of heme oxygenase-1 gene may reduce the incidence of ischemic heart disease through its activity in Japanese)

  尾野 亘; 高木 修一; 宮崎 俊一; 野々木 宏; 後藤 葉一; 岩永 善高; 万波 俊文; 岩井 直温

  日本動脈硬化学会総会プログラム・抄録集, Sep. 2003

  
• Incidence, clinical characteristics and long-term prognosis of postoperative symptomatic venous thromboembolism: a retrospective cohort study.

  Chikashi Takeda; Yugo Yamashita; Masato Takeuchi; Hiroshi Yonekura; Li Dong; Miho Hamada; Akiko Hirotsu; Koh Ono; Koji Kawakami; Kazuhiko Fukuda; Takeshi Morimoto; Takeshi Kimura; Toshiyuki Mizota

  BMJ open, 16 Feb. 2022

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• Matched comparison of catheter ablation versus conservative management for atrial fibrillation.

  Tetsuma Kawaji; Satoshi Shizuta; Kyohei Yamaji; Munekazu Tanaka; Kazuki Kitano; Takanori Aizawa; Shintaro Yamagami; Akihiro Komasa; Takashi Yoshizawa; Masashi Kato; Takafumi Yokomatsu; Shinji Miki; Koh Ono; Takeshi Morimoto; Takeshi Kimura

  Heart and vessels, 06 Feb. 2022

  
• 冠血行再建のFuturability 多枝病変に対する待機的経皮的冠動脈インターベンション(PCI)における一期的PCIと段階的PCIの比較 観察研究(Single-session versus Staged Procedures for Elective Multi-vessel Percutaneous Coronary Intervention: Observational Study)

  豊田 俊彬; 森本 剛; 塩見 紘樹; 山地 杏平; 安藤 献児; 尾野 亘; 静田 聡; 齋藤 成達; 加藤 貴雄; 加地 修一郎; 古川 裕; 中川 義久; 門田 一繁; 堀江 稔; 木村 剛

  日本循環器学会学術集会抄録集, Mar. 2018

  
• ST上昇型急性心筋梗塞と非ST上昇型急性心筋梗塞の短期及び長期予後と死因の比較

  夜久 英憲; 塩見 紘樹; 森本 剛; 山下 侑吾; 古川 裕; 中川 義久; 安藤 献児; 門田 一繁; 阿部 充; 長央 和也; 静田 聡; 尾野 亘; 木村 剛

  日本心臓病学会学術集会抄録, Sep. 2016

  
• Association between serum inflammatory biomarkers and atrial low voltage in patients with atrial fibrillation: A phase 1 FIB-MARK study.

  Tetsuma Kawaji; Koh Ono; Naoya Sowa; Takanori Aizawa; Shun Hojo; Hidenori Yaku; Kenji Nakatsuma; Kazuhisa Kaneda; Masashi Kato; Takafumi Yokomatsu; Satoshi Shizuta; Shinji Miki; Takeshi Kimura

  International journal of cardiology. Heart & vasculature, Dec. 2021

  
• Periprocedural management and clinical outcomes of invasive procedures after venous thromboembolism: from the COMMAND VTE registry.

  Reo Hata; Yugo Yamashita; Takeshi Morimoto; Kazushige Kadota; Hidewo Amano; Ryosuke Murai; Kohei Osakada; Arata Sano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Kosuke Doi; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Yuji Nishimoto; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yuta Tsujisaka; Yuta Seko; Kazuki Matsushita; Fumiya Yoneda; Takao Kato; Koh Ono; Takeshi Kimura

  Journal of thrombosis and thrombolysis, 15 Sep. 2021

  
• Risk factors of thrombotic recurrence and major bleeding in patients with intermediate-risk for recurrence of venous thromboembolism.

  Yugo Yamashita; Hidewo Amano; Takeshi Morimoto; Kazushige Kadota; Reo Hata; Kazuki Matsushita; Kohei Osakada; Arata Sano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Moriaki Inoko; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Yuji Nishimoto; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Takao Kato; Koh Ono; Takeshi Kimura

  Journal of thrombosis and thrombolysis, 06 Jul. 2021

  
• Health improvement framework for actionable treatment planning using a surrogate Bayesian model.

  Kazuki Nakamura; Ryosuke Kojima; Eiichiro Uchino; Koh Ono; Motoko Yanagita; Koichi Murashita; Ken Itoh; Shigeyuki Nakaji; Yasushi Okuno

  Nature communications, 25 May 2021

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• Current Diagnosis and Management of Tangier Disease.

  Masahiro Koseki; Shizuya Yamashita; Masatsune Ogura; Yasushi Ishigaki; Koh Ono; Kazuhisa Tsukamoto; Mika Hori; Kota Matsuki; Shinji Yokoyama; Mariko Harada-Shiba

  Journal of atherosclerosis and thrombosis, 14 May 2021

  
• Homozygous Familial Hypercholesterolemia.

  Atsushi Nohara; Hayato Tada; Masatsune Ogura; Sachiko Okazaki; Koh Ono; Hitoshi Shimano; Hiroyuki Daida; Kazushige Dobashi; Toshio Hayashi; Mika Hori; Kota Matsuki; Tetsuo Minamino; Shinji Yokoyama; Mariko Harada-Shiba

  Journal of atherosclerosis and thrombosis, 18 Apr. 2021

  
• Clinical characteristics and outcomes of patients with venous thromboembolism according to diagnosis on weekends versus on weekdays.

  Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Yusuke Morita; Tomohisa Tada; Toshiaki Izumi; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Yuji Nishimoto; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yusuke Yoshikawa; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Takeshi Kimura

  Journal of thrombosis and thrombolysis, Apr. 2021

  
• Impact of no, distal, and proximal deep vein thrombosis on clinical outcomes in patients with acute pulmonary embolism: From the COMMAND VTE registry.

  Shushi Nishiwaki; Yusuke Morita; Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Moriaki Inoko; Takeshi Kimura

  Journal of cardiology, Apr. 2021

  
• Overview of the 84th Annual Scientific Meeting of the Japanese Circulation Society - Change Practice!

  Koh Ono; Satoshi Shizuta; Erika Yamamoto; Naritatsu Saito; Neiko Ozasa; Takao Kato; Eri Kato; Takahiro Horie; Junichi Tazaki; Hiroki Shiomi; Shin Watanabe; Hirotoshi Watanabe; Yugo Yamashita; Yusuke Yoshikawa; Hideyuki Kinoshita; Takeru Makiyama; Yoshinori Yoshida; Noboru Ashida; Yasuaki Nakagawa; Yasuhiro Nakashima; Osamu Baba; Hirohiko Kohjitani; Masahiro Kimura; Hideaki Inazumi; Takashi Yoshizawa; Akihiro Komasa; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 25 Feb. 2021

  
• microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity.

  Takahiro Horie; Tetsushi Nakao; Yui Miyasaka; Tomohiro Nishino; Shigenobu Matsumura; Fumiko Nakazeki; Yuya Ide; Masahiro Kimura; Shuhei Tsuji; Randolph Ruiz Rodriguez; Toshimitsu Watanabe; Tomohiro Yamasaki; Sijia Xu; Chiharu Otani; Sawa Miyagawa; Kazuki Matsushita; Naoya Sowa; Aoi Omori; Jin Tanaka; Chika Nishimura; Masataka Nishiga; Yasuhide Kuwabara; Osamu Baba; Shin Watanabe; Hitoo Nishi; Yasuhiro Nakashima; Marina R Picciotto; Haruhisa Inoue; Dai Watanabe; Kazuhiro Nakamura; Tsutomu Sasaki; Takeshi Kimura; Koh Ono

  Nature communications, 16 Feb. 2021

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• Autoimmune disorders and venous thromboembolism: An update from the COMMAND VTE registry.

  Yugo Yamashita; Takeshi Morimoto; Kazushige Kadota; Koh Ono; Takeshi Kimura

  European journal of internal medicine, Feb. 2021

  
• Impact of catheter ablation for atrial fibrillation on cardiac disorders in patients with coexisting heart failure.

  Tetsuma Kawaji; Satoshi Shizuta; Takanori Aizawa; Shintaro Yamagami; Masashi Kato; Takafumi Yokomatsu; Shinji Miki; Koh Ono; Takeshi Kimura

  ESC heart failure, Feb. 2021

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• C-reactive protein at discharge and 1-year mortality in hospitalised patients with acute decompensated heart failure: an observational study.

  Yuji Nishimoto; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Koichiro Kuwahara; Neiko Ozasa; Yukihito Sato; Takeshi Kimura

  BMJ open, 29 Dec. 2020

  
• Functional non-coding RNAs in vascular diseases.

  Koh Ono; Takahiro Horie; Osamu Baba; Masahiro Kimura; Shuhei Tsuji; Randolph Ruiz Rodriguez; Sawa Miyagawa; Takeshi Kimura

  The FEBS journal, 19 Dec. 2020

  
• Risk Factors for Major Bleeding During Anticoagulation Therapy in Cancer-Associated Venous Thromboembolism - From the COMMAND VTE Registry.

  Yuji Nishimoto; Yugo Yamashita; Kitae Kim; Takeshi Morimoto; Syunsuke Saga; Hidewo Amano; Toru Takase; Seiichi Hiramori; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yusuke Yoshikawa; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Yukihito Sato; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 23 Oct. 2020

  
• Sex differences in patients with acute decompensated heart failure in Japan: observation from the KCHF registry.

  Erika Yamamoto; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Yoshihiro Himura; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mitsunori Kawato; Yuta Seko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura

  ESC heart failure, Oct. 2020

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• Lionheart LincRNA alleviates cardiac systolic dysfunction under pressure overload.

  Yasuhide Kuwabara; Shuhei Tsuji; Masataka Nishiga; Masayasu Izuhara; Shinji Ito; Kazuya Nagao; Takahiro Horie; Shin Watanabe; Satoshi Koyama; Hisanori Kiryu; Yasuhiro Nakashima; Osamu Baba; Tetsushi Nakao; Tomohiro Nishino; Naoya Sowa; Yui Miyasaka; Takeshi Hatani; Yuya Ide; Fumiko Nakazeki; Masahiro Kimura; Yoshinori Yoshida; Tsukasa Inada; Takeshi Kimura; Koh Ono

  Communications biology, 13 Aug. 2020

  
• 髄芽腫の発生と発育におけるmi-R33の役割

  峰晴 陽平; 松井 恭澄; 森本 貴昭; 尾市 雄輝; 鎌田 貴彦; 丹治 正大; 中尾 哲史; 堀江 貴裕; 尾野 亘; 荒川 芳輝

  Brain Tumor Pathology, Aug. 2020

  
• Predictive ability of modified Ottawa score for recurrence in patients with cancer-associated venous thromboembolism: From the COMMAND VTE Registry.

  Yuji Nishimoto; Yugo Yamashita; Takeshi Morimoto; Syunsuke Saga; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yusuke Yoshikawa; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Yukihito Sato; Takeshi Kimura

  Thrombosis research, Jul. 2020

  
• Prediction of Coronary Artery Disease by Measurement of Circulating MicroRNA-423-3p Levels.

  Koh Ono

  Circulation journal : official journal of the Japanese Circulation Society, 25 Jun. 2020

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• Effects of Metformin on Left Ventricular Size and Function in Hypertensive Patients with Type 2 Diabetes Mellitus: Results of a Randomized, Controlled, Multicenter, Phase IV Trial.

  Koh Ono; Hiromichi Wada; Noriko Satoh-Asahara; Hitoki Inoue; Keita Uehara; Junichi Funada; Atsushi Ogo; Takahiro Horie; Masatoshi Fujita; Akira Shimatsu; Koji Hasegawa

  American journal of cardiovascular drugs : drugs, devices, and other interventions, Jun. 2020, Peer-reviewed

  
• Validation of simplified PESI score for identification of low-risk patients with pulmonary embolism: From the COMMAND VTE Registry.

  Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Takeshi Kimura

  European heart journal. Acute cardiovascular care, Jun. 2020, Peer-reviewed

  
• D-dimer levels at diagnosis and long-term clinical outcomes in venous thromboembolism: from the COMMAND VTE Registry.

  Maki Oi; Yugo Yamashita; Mamoru Toyofuku; Takeshi Morimoto; Yasuyo Motohashi; Takashi Tamura; Kazuaki Kaitani; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Masaharu Akao; Yohei Kobayashi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Takeshi Kimura

  Journal of thrombosis and thrombolysis, May 2020, Peer-reviewed

  
• Homeobox A4 suppresses vascular remodeling by repressing YAP/TEAD transcriptional activity.

  Masahiro Kimura; Takahiro Horie; Osamu Baba; Yuya Ide; Shuhei Tsuji; Randolph Ruiz Rodriguez; Toshimitsu Watanabe; Tomohiro Yamasaki; Chiharu Otani; Sijia Xu; Yui Miyasaka; Yasuhiro Nakashima; Takeshi Kimura; Koh Ono

  EMBO reports, 03 Apr. 2020, Peer-reviewed

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• Renal dysfunction and long-term clinical outcomes in patients with venous thromboembolism: From the COMMAND VTE Registry.

  Yoshiaki Tsuyuki; Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Yohei Kobayashi; Koh Ono; Takeshi Aoyama; Takeshi Kimura

  Thrombosis research, Mar. 2020

  
• Usefulness of Simplified Pulmonary Embolism Severity Index Score for Identification of Patients With Low-Risk Pulmonary Embolism and Active Cancer: From the COMMAND VTE Registry

  Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Yuji Nishimoto; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yusuke Yoshikawa; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Takeshi Kimura

  Chest, Mar. 2020, Peer-reviewed

  
• Validation of the VTE-BLEED score's long-term performance for major bleeding in patients with venous thromboembolisms: From the COMMAND VTE registry.

  Yuji Nishimoto; Yugo Yamashita; Takeshi Morimoto; Syunsuke Saga; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Yusuke Yoshikawa; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Yukihito Sato; Takeshi Kimura

  Journal of thrombosis and haemostasis : JTH, Mar. 2020, Peer-reviewed

  
• Association with Controlling Nutritional Status (CONUT) Score and In-hospital Mortality and Infection in Acute Heart Failure.

  Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Neiko Ozasa; Takeshi Kimura

  Scientific reports, 24 Feb. 2020

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• Temporal Trends in the Practice Pattern for Venous Thromboembolism in Japan: Insight From JROAD-DPC.

  Yugo Yamashita; Takeshi Morimoto; Yusuke Yoshikawa; Hidenori Yaku; Yoko Sumita; Michikazu Nakai; Koh Ono; Takeshi Kimura

  Journal of the American Heart Association, 21 Jan. 2020

  
• Effect of Statins on Recurrent Venous Thromboembolism (from the COMMAND VTE Registry).

  Yusuke Yoshikawa; Yugo Yamashita; Takeshi Morimoto; Hiroshi Mabuchi; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Yuji Nishimoto; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Tomoyuki Murakami; Takeshi Kimura

  The American journal of cardiology, 15 Jan. 2020, Peer-reviewed

  
• Utility of collagen-derived peptides as markers of organ injury in patients with acute heart failure.

  Kazuya Nagao; Akinori Tamura; Yukihito Sato; Reo Hata; Yuichi Kawase; Kazushige Kadota; Takahiro Horie; Naoya Sowa; Masataka Nishiga; Koh Ono; Tsukasa Inada; Masaru Tanaka

  Open heart, 2020

  
• Renal function and outcomes in atrial fibrillation patients after catheter ablation.

  Tetsuma Kawaji; Satoshi Shizuta; Takanori Aizawa; Shintaro Yamagami; Yasuaki Takeji; Yusuke Yoshikawa; Masashi Kato; Takafumi Yokomatsu; Shinji Miki; Koh Ono; Takeshi Kimura

  PloS one, 2020

  
• Clinical outcomes of patients with pulmonary embolism versus deep vein thrombosis: From the COMMAND VTE Registry.

  Yugo Yamashita; Koichiro Murata; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Yoshiaki Tsuyuki; Syunsuke Saga; Yuji Nishimoto; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yusuke Yoshikawa; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Ryuzo Nawada; Tomoya Onodera; Takeshi Kimura

  Thrombosis research, Dec. 2019, Peer-reviewed

  
• Thrombolysis with tissue plasminogen activator in patients with acute pulmonary embolisms in the real world: from the COMMAND VTE registry.

  Yuji Nishimoto; Yugo Yamashita; Takeshi Morimoto; Syunsuke Saga; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yusuke Yoshikawa; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Yukihito Sato; Takeshi Kimura

  Journal of thrombosis and thrombolysis, Nov. 2019, Peer-reviewed

  
• Cancer-Associated Venous Thromboembolism in the Real World - From the COMMAND VTE Registry.

  Jiro Sakamoto; Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Yuji Nishimoto; Tomoki Sasa; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yusuke Yoshikawa; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Toshihiro Tamura; Yoshihisa Nakagawa; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 25 Oct. 2019, Peer-reviewed

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• Cardioprotective Effects of VCP Modulator KUS121 in Murine and Porcine Models of Myocardial Infarction.

  Yuya Ide; Takahiro Horie; Naritatsu Saito; Shin Watanabe; Chiharu Otani; Yui Miyasaka; Yasuhide Kuwabara; Tomohiro Nishino; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Fumiko Nakazeki; Satoshi Koyama; Masahiro Kimura; Shuhei Tsuji; Randolph Ruiz Rodriguez; Sijia Xu; Tomohiro Yamasaki; Toshimitsu Watanabe; Masamichi Yamamoto; Motoko Yanagita; Takeshi Kimura; Akira Kakizuka; Koh Ono

  JACC. Basic to translational science, Oct. 2019, Peer-reviewed

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• Utility of simplified PESI score for identification of low-risk pulmonary embolism patients with active cancer: From the COMMAND VTE Registry.

  Yamashita Y; Morimoto T; Amano H; Takase T; Hiramori S; Kim K; Oi M; Akao M; Kobayashi Y; Toyofuku M; Izumi T; Tada T; Chen PM; Murata K; Tsuyuki Y; Nishimoto Y; Saga S; Sasa T; Sakamoto J; Kinoshita M; Togi K; Mabuchi H; Takabayashi K; Yoshikawa Y; Shiomi H; Kato T; Makiyama T; Ono K; Kimura T; COMMAND VTE Registry Investigators

  Chest, Oct. 2019, Peer-reviewed

  
• The association of recurrence and bleeding events with mortality after venous thromboembolism: From the COMMAND VTE Registry.

  Yugo Yamashita; Yusuke Yoshikawa; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Takeshi Kimura

  International journal of cardiology, 01 Oct. 2019, Peer-reviewed

  
• Early choice for catheter ablation reduced readmission in management of atrial fibrillation: Impact of diagnosis-to-ablation time.

  Tetsuma Kawaji; Satoshi Shizuta; Shintaro Yamagami; Takanori Aizawa; Akihiro Komasa; Takashi Yoshizawa; Masashi Kato; Takafumi Yokomatsu; Shinji Miki; Koh Ono; Takeshi Kimura

  International journal of cardiology, 15 Sep. 2019, Peer-reviewed

  
• Risk Factors for Major Bleeding during Prolonged Anticoagulation Therapy in Patients with Venous Thromboembolism: From the COMMAND VTE Registry.

  Kitae Kim; Yugo Yamashita; Takeshi Morimoto; Takeshi Kitai; Takafumi Yamane; Natsuhiko Ehara; Makoto Kinoshita; Shuichiro Kaji; Hidewo Amano; Toru Takase; Seiichi Hiramori; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Yutaka Furukawa; Takeshi Kimura

  Thrombosis and haemostasis, Sep. 2019, Peer-reviewed

  
• Optimal Cutoff Value of Fractional Flow Reserve Derived From Coronary Computed Tomography Angiography for Predicting Hemodynamically Significant Coronary Artery Disease.

  Yukiko Matsumura-Nakano; Tetsuma Kawaji; Hiroki Shiomi; Kanae Kawai-Miyake; Masako Kataoka; Koji Koizumi; Akira Matsuda; Kazuki Kitano; Masaharu Yoshida; Hirotoshi Watanabe; Junichi Tazaki; Takao Kato; Naritatsu Saito; Satoshi Shizuta; Koh Ono; Kaori Togashi; Takeshi Morimoto; Takeshi Kimura

  Circulation. Cardiovascular imaging, Aug. 2019, Peer-reviewed

  
• More- Versus Less-Intensive Lipid-Lowering Therapy.

  Toshiaki Toyota; Takeshi Morimoto; Yugo Yamashita; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Yasuaki Nakagawa; Naritatsu Saito; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  Circulation. Cardiovascular quality and outcomes, Aug. 2019, Peer-reviewed

  
• Identification of Differential Roles of MicroRNA-33a and -33b During Atherosclerosis Progression With Genetically Modified Mice.

  Satoshi Koyama; Takahiro Horie; Tomohiro Nishino; Osamu Baba; Naoya Sowa; Yui Miyasaka; Yasuhide Kuwabara; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Fumiko Nakazeki; Yuya Ide; Masahiro Kimura; Shuhei Tsuji; Randolph Ruiz Rodriguez; Sijia Xu; Tomohiro Yamasaki; Chiharu Otani; Toshimitsu Watanabe; Tomoyuki Nakamura; Koji Hasegawa; Takeshi Kimura; Koh Ono

  Journal of the American Heart Association, 02 Jul. 2019, Peer-reviewed

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• アテローム性動脈硬化形成におけるmicroRNA-33aおよび-33bが与える影響の違いについての検討

  宮阪 由依; 小山 智志; 堀江 貴裕; 藤井 康友; 木村 剛; 尾野 亘

  日本動脈硬化学会総会プログラム・抄録集, Jul. 2019

  
• Sex Differences in Clinical Characteristics and Outcomes of Patients With Venous Thromboembolism - From the COMMAND VTE Registry.

  Yusuke Yoshikawa; Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 25 Jun. 2019, Peer-reviewed

  
• Association of Mineralocorticoid Receptor Antagonist Use With All-Cause Mortality and Hospital Readmission in Older Adults With Acute Decompensated Heart Failure.

  Hidenori Yaku; Takao Kato; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yuta Seko; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura

  JAMA network open, 05 Jun. 2019, Peer-reviewed

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• Clinical Characteristics and Outcomes of Venous Thromboembolisms According to an Out-of-Hospital vs. In-Hospital Onset - From the COMMAND VTE Registry.

  Yuji Nishimoto; Yugo Yamashita; Takeshi Morimoto; Syunsuke Saga; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Yukihito Sato; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 24 May 2019, Peer-reviewed

  
• Deep vein thrombosis in upper extremities: Clinical characteristics, management strategies and long-term outcomes from the COMMAND VTE Registry.

  Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Yuji Nishimoto; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Yusuke Yoshikawa; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Takeshi Kimura

  Thrombosis research, May 2019, Peer-reviewed

  
• Utility of copeptin for predicting long-term clinical outcomes in patients with heart failure.

  Yusuke Yoshikawa; Hiroki Shiomi; Koichiro Kuwahara; Naoya Sowa; Hidenori Yaku; Yugo Yamashita; Junichi Tazaki; Masao Imai; Takao Kato; Naritatsu Saito; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  Journal of cardiology, May 2019, Peer-reviewed

  
• アテローム性動脈硬化形成におけるmicroRNA-33aおよび-33bが与える影響の違いについての検討

  宮阪 由依; 小山 智史; 堀江 貴裕; 藤井 康友; 木村 剛; 尾野 亘

  日本臨床分子医学会学術総会プログラム・抄録集, Apr. 2019

  
• Influence of baseline anemia on long-term clinical outcomes in patients with venous thromboembolism: from the COMMAND VTE registry.

  Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Takeshi Kimura

  Journal of thrombosis and thrombolysis, Apr. 2019, Peer-reviewed

  
• Risk factors for post-thrombotic syndrome in patients with deep vein thrombosis: from the COMMAND VTE registry.

  Yuji Nishimoto; Yugo Yamashita; Takeshi Morimoto; Syunsuke Saga; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Yukihito Sato; Takeshi Kimura

  Heart and vessels, Apr. 2019, Peer-reviewed

  
• MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.

  Fumiko Nakazeki; Itaru Tsuge; Takahiro Horie; Keiko Imamura; Kayoko Tsukita; Akitsu Hotta; Osamu Baba; Yasuhide Kuwabara; Tomohiro Nishino; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Shuhei Tsuji; Motoko Naitoh; Shigehiko Suzuki; Yuishin Izumi; Toshitaka Kawarai; Ryuji Kaji; Takeshi Kimura; Haruhisa Inoue; Koh Ono

  Clinical science (London, England : 1979), 28 Feb. 2019, Peer-reviewed

  
• Real-time surveillance of left atrial appendage thrombus during contrast computed tomography imaging for catheter ablation: THe Reliability of cOMputed tomography Beyond UltraSound in THROMBUS detection (THROMBUS) study.

  Tetsuma Kawaji; Hitomi Numamoto; Shintaro Yamagami; Ryu Mabuchi; Takaaki Kitamura; Naomi Enoki; Koji Koizumi; Shotaro Kanao; Masashi Kato; Takafumi Yokomatsu; Satoshi Shizuta; Shinji Miki; Koh Ono; Kaori Togashi; Takeshi Kimura

  Journal of thrombosis and thrombolysis, Jan. 2019, Peer-reviewed

  
• Mortality impact of post-discharge myocardial infarction size after percutaneous coronary intervention: a patient-level pooled analysis from the 4 large-scale Japanese studies.

  Hirotoshi Watanabe; Takeshi Morimoto; Hiroki Shiomi; Yusuke Yoshikawa; Takao Kato; Naritatsu Saito; Satoshi Shizuta; Koh Ono; Kyohei Yamaji; Kenji Ando; Shuichiro Kaji; Yutaka Furukawa; Masaharu Akao; Tetsuya Ishikawa; Takashi Tamura; Yoshito Yamamoto; Toshiya Muramatsu; Satoru Suwa; Yoshihisa Nakagawa; Kazushige Kadota; Yoshiki Takatsu; Hideo Nishikawa; Yoshikazu Hiasa; Yasuhiko Hayashi; Shunichi Miyazaki; Takeshi Kimura

  Cardiovascular intervention and therapeutics, Jan. 2019, Peer-reviewed

  
• Influence of Baseline Platelet Count on Outcomes in Patients With Venous Thromboembolism (from the COMMAND VTE Registry).

  Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Maki Oi; Masaharu Akao; Yohei Kobayashi; Mamoru Toyofuku; Toshiaki Izumi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Minako Kinoshita; Kiyonori Togi; Hiroshi Mabuchi; Kensuke Takabayashi; Hirotoshi Watanabe; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Koh Ono; Takeshi Kimura

  The American journal of cardiology, 15 Dec. 2018, Peer-reviewed

  
• Circulating markers of collagen types I, III, and IV in patients with dilated cardiomyopathy: relationships with myocardial collagen expression.

  Kazuya Nagao; Tsukasa Inada; Akinori Tamura; Kenji Kajitani; Kiyotaka Shimamura; Hiroshi Yukawa; Kenji Aida; Naoya Sowa; Masataka Nishiga; Takahiro Horie; Toshinori Makita; Koh Ono; Masaru Tanaka

  ESC heart failure, Dec. 2018, Peer-reviewed

  
• Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction.

  Daihiko Hakuno; Masahiro Kimura; Shinji Ito; Junko Satoh; Yasuhiro Nakashima; Takahiro Horie; Yasuhide Kuwabara; Masataka Nishiga; Yuya Ide; Osamu Baba; Hitoo Nishi; Tetsushi Nakao; Tomohiro Nishino; Fumiko Nakazeki; Satoshi Koyama; Ritsuko Hanada; Ruiz R Randolph; Jin Endo; Takeshi Kimura; Koh Ono

  Scientific reports, 13 Nov. 2018, Peer-reviewed

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• Demographics, Management, and In-Hospital Outcome of Hospitalized Acute Heart Failure Syndrome Patients in Contemporary Real Clinical Practice in Japan - Observations From the Prospective, Multicenter Kyoto Congestive Heart Failure (KCHF) Registry.

  Hidenori Yaku; Neiko Ozasa; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Kenichi Sasaki; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Takao Kato; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 25 Oct. 2018, Peer-reviewed

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• SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo.

  Tomohiro Nishino; Takahiro Horie; Osamu Baba; Naoya Sowa; Ritsuko Hanada; Yasuhide Kuwabara; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Fumiko Nakazeki; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Manabu Nagata; Kazumichi Yoshida; Yasushi Takagi; Tomoyuki Nakamura; Koji Hasegawa; Susumu Miyamoto; Takeshi Kimura; Koh Ono

  Arteriosclerosis, thrombosis, and vascular biology, Oct. 2018, Peer-reviewed

  
• Therapeutic angiogenesis by local sustained release of microRNA-126 using poly lactic-co-glycolic acid nanoparticles in murine hindlimb ischemia.

  Shinichi Tsumaru; Hidetoshi Masumoto; Kenji Minakata; Masayasu Izuhara; Kazuhiro Yamazaki; Tadashi Ikeda; Koh Ono; Ryuzo Sakata; Kenji Minatoya

  Journal of vascular surgery, Oct. 2018, Peer-reviewed

  
• Impact of Pre-Existing Bradycardia on Subsequent Need for Pacemaker Implantation After Radiofrequency Catheter Ablation for Atrial Fibrillation.

  Tetsuma Kawaji; Satoshi Shizuta; Shintaro Yamagami; Takanori Aizawa; Takashi Yoshizawa; Masashi Kato; Takafumi Yokomatsu; Shinji Miki; Koh Ono; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 25 Sep. 2018, Peer-reviewed

  
• MicroRNA 33 Regulates the Population of Peripheral Inflammatory Ly6Chigh Monocytes through Dual Pathways.

  Osamu Baba; Takahiro Horie; Tetsushi Nakao; Daihiko Hakuno; Yasuhiro Nakashima; Hitoo Nishi; Yasuhide Kuwabara; Masataka Nishiga; Tomohiro Nishino; Yuya Ide; Fumiko Nakazeki; Satoshi Koyama; Masahiro Kimura; Ritsuko Hanada; Masahiro Kawahara; Takeshi Kimura; Koh Ono

  Molecular and cellular biology, 15 Jul. 2018, Peer-reviewed

  
• Influence of a history of cancer on long-term cardiovascular outcomes after coronary stent implantation (an Observation from Coronary Revascularization Demonstrating Outcome Study-Kyoto Registry Cohort-2).

  Kenji Nakatsuma; Hiroki Shiomi; Takeshi Morimoto; Hirotoshi Watanabe; Yoshihisa Nakagawa; Yutaka Furukawa; Kazushige Kadota; Kenji Ando; Koh Ono; Satoshi Shizuta; Takeshi Kimura

  European heart journal. Quality of care & clinical outcomes, 01 Jul. 2018, Peer-reviewed

  
• Rare variants in RNF213, a susceptibility gene for moyamoya disease, are found in patients with pulmonary hypertension and aggravate hypoxia-induced pulmonary hypertension in mice.

  Kobayashi H; Kabata R; Kinoshita H; Morimoto T; Ono K; Takeda M; Choi J; Okuda H; Liu W; Harada KH; Kimura T; Youssefian S; Koizumi A

  Pulmonary circulation, Jul. 2018, Peer-reviewed

  
• Loss of periostin ameliorates adipose tissue inflammation and fibrosis in vivo.

  Fumiko Nakazeki; Masataka Nishiga; Takahiro Horie; Hitoo Nishi; Yasuhiro Nakashima; Osamu Baba; Yasuhide Kuwabara; Tomohiro Nishino; Tetsushi Nakao; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Shuhei Tsuji; Naoya Sowa; Shigeo Yoshida; Simon J Conway; Motoko Yanagita; Takeshi Kimura; Koh Ono

  Scientific reports, 04 Jun. 2018, Peer-reviewed

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• Clinical Utility of Intravenous Nifekalant Injection during Radiofrequency catheter Ablation for Persistent Atrial Fibrillation.

  Kawaji T; Shizuta S; Yamagami S; Aizawa T; Komasa A; Yoshizawa T; Kato M; Yokomatsu T; Miki S; Ono K; Kimura T

  Journal of atrial fibrillation, Jun. 2018, Peer-reviewed

  
• Single-session versus staged procedures for elective multivessel percutaneous coronary intervention.

  Toshiaki Toyota; Takeshi Morimoto; Hiroki Shiomi; Kyohei Yamaji; Kenji Ando; Koh Ono; Satoshi Shizuta; Naritatsu Saito; Takao Kato; Shuichiro Kaji; Yutaka Furukawa; Yoshihisa Nakagawa; Kazushige Kadota; Minoru Horie; Takeshi Kimura

  Heart (British Cardiac Society), Jun. 2018, Peer-reviewed

  
• Preclinical evaluation of a paclitaxel-incorporated nanoparticle-coated balloon in rabbit and porcine models.

  Erika Yamamoto; Shin Watanabe; Bingyuan Bao; Hiroki Watanabe; Kenji Nakatsuma; Masayasu Izuhara; Koh Ono; Gaku Nakazawa; Takeshi Kimura; Naritatsu Saito

  Cardiovascular revascularization medicine : including molecular interventions, Jun. 2018, Peer-reviewed

  
• Impact of Baseline Thrombocytopenia on Bleeding and Mortality After Percutaneous Coronary Intervention.

  Shinya Ito; Hirotoshi Watanabe; Takeshi Morimoto; Yusuke Yoshikawa; Hiroki Shiomi; Satoshi Shizuta; Koh Ono; Kyohei Yamaji; Yoshimitsu Soga; Makoto Hyodo; Shinichi Shirai; Kenji Ando; Hisanori Horiuchi; Takeshi Kimura

  The American journal of cardiology, 01 Jun. 2018, Peer-reviewed

  
• Asian patients versus non-Asian patients in the efficacy and safety of direct oral anticoagulants relative to vitamin K antagonist for venous thromboembolism: A systemic review and meta-analysis.

  Yugo Yamashita; Takeshi Morimoto; Toshiaki Toyota; Hiroki Shiomi; Takeru Makiyama; Koh Ono; Takeshi Kimura

  Thrombosis research, Jun. 2018, Peer-reviewed

  
• Long Non-Coding RNAs as Key Regulators of Cardiovascular Diseases.

  Koh Ono; Yasuhide Kuwabara; Takahiro Horie; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 25 Apr. 2018, Peer-reviewed

  
• Anticoagulation Therapy for Venous Thromboembolism in the Real World - From the COMMAND VTE Registry.

  Yugo Yamashita; Takeshi Morimoto; Hidewo Amano; Toru Takase; Seiichi Hiramori; Kitae Kim; Takashi Konishi; Masaharu Akao; Yohei Kobayashi; Takeshi Inoue; Maki Oi; Toshiaki Izumi; Kotaro Takahashi; Tomohisa Tada; Po-Min Chen; Koichiro Murata; Yoshiaki Tsuyuki; Hiroshi Sakai; Syunsuke Saga; Tomoki Sasa; Jiro Sakamoto; Chinatsu Yamada; Minako Kinoshita; Kiyonori Togi; Tomoyuki Ikeda; Katsuhisa Ishii; Kazuhisa Kaneda; Hiroshi Mabuchi; Hideo Otani; Kensuke Takabayashi; Mamoru Takahashi; Hiroki Shiomi; Takeru Makiyama; Koh Ono; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 25 Apr. 2018, Peer-reviewed

  
• Association between monocyte chemoattractant protein-1 and blood pressure in smokers.

  Maki Komiyama; Rieko Takanabe; Koh Ono; Sayaka Shimada; Hiromichi Wada; Hajime Yamakage; Noriko Satoh-Asahara; Tatsuya Morimoto; Akira Shimatsu; Yuko Takahashi; Koji Hasegawa

  The Journal of international medical research, Mar. 2018, Peer-reviewed

  
• Prognostic Impact of Left Ventricular Ejection Fraction in Patients With Severe Aortic Stenosis.

  Tomohiko Taniguchi; Takeshi Morimoto; Hiroki Shiomi; Kenji Ando; Norio Kanamori; Koichiro Murata; Takeshi Kitai; Kazushige Kadota; Chisato Izumi; Kenji Nakatsuma; Tomoki Sasa; Hirotoshi Watanabe; Yasuhide Kuwabara; Takeru Makiyama; Koh Ono; Satoshi Shizuta; Takao Kato; Naritatsu Saito; Kenji Minatoya; Takeshi Kimura

  JACC. Cardiovascular interventions, 22 Jan. 2018, Peer-reviewed

  
• Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction.

  Hao Wang; Xiao-Meng Zhang; Go Tomiyoshi; Rika Nakamura; Natsuko Shinmen; Hideyuki Kuroda; Risa Kimura; Seiichiro Mine; Ikuo Kamitsukasa; Takeshi Wada; Akiyo Aotsuka; Yoichi Yoshida; Eiichi Kobayashi; Tomoo Matsutani; Yasuo Iwadate; Kazuo Sugimoto; Masahiro Mori; Akiyuki Uzawa; Mayumi Muto; Satoshi Kuwabara; Minoru Takemoto; Kazuki Kobayashi; Harukiyo Kawamura; Ryoichi Ishibashi; Koutaro Yokote; Mikiko Ohno; Po-Min Chen; Eiichiro Nishi; Koh Ono; Takeshi Kimura; Toshio Machida; Hirotaka Takizawa; Koichi Kashiwado; Hideaki Shimada; Masaaki Ito; Ken-Ichiro Goto; Katsuro Iwase; Hiromi Ashino; Akiko Taira; Emiko Arita; Masaki Takiguchi; Takaki Hiwasa

  Oncotarget, 19 Jan. 2018, Peer-reviewed

  
• Smoking cessation reduces the lectin-like low-density lipoprotein receptor index, an independent cardiovascular risk marker of vascular inflammation.

  Maki Komiyama; Hiromichi Wada; Koh Ono; Hajime Yamakage; Noriko Satoh-Asahara; Sayaka Shimada; Masaharu Akao; Tatsuya Morimoto; Akira Shimatsu; Yuko Takahashi; Tatsuya Sawamura; Koji Hasegawa

  Heart and vessels, Jan. 2018, Peer-reviewed

  
• Short versus prolonged dual antiplatelet therapy duration after bare-metal stent implantation: 2-month landmark analysis from the CREDO-Kyoto registry cohort-2.

  Masahiro Natsuaki; Takeshi Morimoto; Yutaka Furukawa; Yoshihisa Nakagawa; Kazushige Kadota; Kenji Ando; Hiroki Shiomi; Toshiaki Toyota; Hirotoshi Watanabe; Koh Ono; Satoshi Shizuta; Takashi Tamura; Moriaki Inoko; Tsukasa Inada; Manabu Shirotani; Mitsuo Matsuda; Takeshi Aoyama; Tomoya Onodera; Satoru Suwa; Teruki Takeda; Katsumi Inoue; Takeshi Kimura

  Cardiovascular intervention and therapeutics, Jan. 2018, Peer-reviewed

  
• Very long-term clinical outcomes after radiofrequency catheter ablation for atrial fibrillation: A large single-center experience.

  Tetsuma Kawaji; Satoshi Shizuta; Takeshi Morimoto; Takanori Aizawa; Shintaro Yamagami; Takashi Yoshizawa; Chihiro Ota; Naoaki Onishi; Yasuhiro Sasaki; Mitsuhiko Yahata; Kentaro Nakai; Mamoru Hayano; Tetsushi Nakao; Koji Hanazawa; Koji Goto; Takahiro Doi; Koh Ono; Takeshi Kimura

  International journal of cardiology, 15 Dec. 2017, Peer-reviewed

  
• Impact of Transient or Persistent Contrast-induced Nephropathy on Long-term Mortality After Elective Percutaneous Coronary Intervention.

  Mitsuru Abe; Takeshi Morimoto; Yoshihisa Nakagawa; Yutaka Furukawa; Koh Ono; Takao Kato; Kazushige Kadota; Kenji Ando; Mitsuru Ishii; Nobutoyo Masunaga; Masaharu Akao; Takeshi Kimura

  The American journal of cardiology, 15 Dec. 2017, Peer-reviewed

  
• Imbalanced expression of polycistronic miRNA in acute myeloid leukemia.

  Ryutaro Kotaki; Hiroshi Higuchi; Daisuke Ogiya; Yasuhiro Katahira; Natsumi Kurosaki; Naoko Yukihira; Jun Ogata; Haruna Yamamoto; Syakira Mohamad Alba; Azran Azhim; Tatsuo Kitajima; Shigeaki Inoue; Kazuhiro Morishita; Koh Ono; Ryo Koyama-Nasu; Ai Kotani

  International journal of hematology, Dec. 2017, Peer-reviewed

  
• Transradial versus transfemoral approach in patients undergoing primary percutaneous coronary intervention for ST-elevation acute myocardial infarction: insight from the CREDO-Kyoto AMI registry.

  Yugo Yamashita; Hiroki Shiomi; Takeshi Morimoto; Hidenori Yaku; Shuichiro Kaji; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Mitsuru Abe; Masaharu Akao; Kazuya Nagao; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  Heart and vessels, Dec. 2017, Peer-reviewed

  
• Development of a Patient-Derived Induced Pluripotent Stem Cell Model for the Investigation of SCN5A-D1275N-Related Cardiac Sodium Channelopathy.

  Mamoru Hayano; Takeru Makiyama; Tsukasa Kamakura; Hiroshi Watanabe; Kenichi Sasaki; Shunsuke Funakoshi; Yimin Wuriyanghai; Suguru Nishiuchi; Takeshi Harita; Yuta Yamamoto; Hirohiko Kohjitani; Sayako Hirose; Fumika Yokoi; Jiarong Chen; Osamu Baba; Takahiro Horie; Kazuhisa Chonabayashi; Seiko Ohno; Futoshi Toyoda; Yoshinori Yoshida; Koh Ono; Minoru Horie; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 24 Nov. 2017, Peer-reviewed

  
• Asymptomatic Lower Extremity Deep Vein Thrombosis - Clinical Characteristics, Management Strategies, and Long-Term Outcomes.

  Yugo Yamashita; Hiroki Shiomi; Takeshi Morimoto; Tomoya Yoneda; Chinatsu Yamada; Takeru Makiyama; Takao Kato; Naritatsu Saito; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 24 Nov. 2017, Peer-reviewed

  
• Human iPSC-Derived Myocyte Mmodel of SCN5A-D1275N-Related Cardiac Sodium Channelopathy Reveals Diminished Sodium Currents Resulting From Enhanced Protein Degradation

  Hayano Mamoru; Makiyama Takeru; Kamakura Tsukasa; Watanabe Hiroshi; Sasaki Kenichi; Funakoshi Shunsuke; Wuriyanghai Yimin; Nishiuchi Suguru; Harita Takeshi; Yamamoto Yuta; Kohjitani Hirohiko; Hirose Sayako; Yokoi Fumika; Chen Jiarong; Baba Osamu; Horie Takahiro; Chonabayashi Kazuhisa; Ohno Seiko; Toyoda Futoshi; Yoshida Yoshinori; Ono Koh; Horie Minoru; Kimura Takeshi

  CIRCULATION, 14 Nov. 2017, Peer-reviewed

  
• Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways.

  Tetsushi Nakao; Takahiro Horie; Osamu Baba; Masataka Nishiga; Tomohiro Nishino; Masayasu Izuhara; Yasuhide Kuwabara; Hitoo Nishi; Shunsuke Usami; Fumiko Nakazeki; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Naoya Sowa; Satoko Ohno; Hiroki Aoki; Koji Hasegawa; Kazuhisa Sakamoto; Kenji Minatoya; Takeshi Kimura; Koh Ono

  Arteriosclerosis, thrombosis, and vascular biology, Nov. 2017, Peer-reviewed

  
• Nardilysin is a promising biomarker for the early diagnosis of acute coronary syndrome.

  Po-Min Chen; Mikiko Ohno; Takaki Hiwasa; Kiyoto Nishi; Sayaka Saijo; Jiro Sakamoto; Yusuke Morita; Shintaro Matsuda; Shin Watanabe; Yasuhide Kuwabara; Koh Ono; Masao Imai; Katsumi Inoue; Tatsuya Murai; Tsukasa Inada; Masaru Tanaka; Toru Kita; Takeshi Kimura; Eiichiro Nishi

  International journal of cardiology, 15 Sep. 2017, Peer-reviewed

  
• Incidence and Prognostic Impact of Heart Failure Hospitalization During Follow-Up After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction.

  Tomohiko Taniguchi; Hiroki Shiomi; Takeshi Morimoto; Hirotoshi Watanabe; Koh Ono; Satoshi Shizuta; Takao Kato; Naritatsu Saito; Shuichiro Kaji; Kenji Ando; Kazushige Kadota; Yutaka Furukawa; Yoshihisa Nakagawa; Minoru Horie; Takeshi Kimura

  The American journal of cardiology, 01 Jun. 2017, Peer-reviewed

  
• Dynamic changes of serum microRNA-122-5p through therapeutic courses indicates amelioration of acute liver injury accompanied by acute cardiac decompensation.

  Satoshi Koyama; Takashi Kuragaichi; Yukihito Sato; Yasuhide Kuwabara; Shunsuke Usami; Takahiro Horie; Osamu Baba; Daihiko Hakuno; Yasuhiro Nakashima; Tomohiro Nishino; Masataka Nishiga; Tetsushi Nakao; Hidenori Arai; Takeshi Kimura; Koh Ono

  ESC heart failure, May 2017, Peer-reviewed

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• Ad hoc vs. Non-ad hoc Percutaneous Coronary Intervention Strategies in Patients With Stable Coronary Artery Disease.

  Toshiaki Toyota; Takeshi Morimoto; Hiroki Shiomi; Kenji Ando; Koh Ono; Satoshi Shizuta; Takao Kato; Naritatsu Saito; Yutaka Furukawa; Yoshihisa Nakagawa; Minoru Horie; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 24 Mar. 2017, Peer-reviewed

  
• MicroRNA-33 Controls Adaptive Fibrotic Response in the Remodeling Heart by Preserving Lipid Raft Cholesterol.

  Masataka Nishiga; Takahiro Horie; Yasuhide Kuwabara; Kazuya Nagao; Osamu Baba; Tetsushi Nakao; Tomohiro Nishino; Daihiko Hakuno; Yasuhiro Nakashima; Hitoo Nishi; Fumiko Nakazeki; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Ritsuko Hanada; Tomoyuki Nakamura; Tsukasa Inada; Koji Hasegawa; Simon J Conway; Toru Kita; Takeshi Kimura; Koh Ono

  Circulation research, 03 Mar. 2017, Peer-reviewed

  
• Feasibility and diagnostic performance of fractional flow reserve measurement derived from coronary computed tomography angiography in real clinical practice.

  Tetsuma Kawaji; Hiroki Shiomi; Hiroshi Morishita; Takeshi Morimoto; Charles A Taylor; Shotaro Kanao; Koji Koizumi; Satoshi Kozawa; Kazuhisa Morihiro; Hirotoshi Watanabe; Junichi Tazaki; Masao Imai; Naritatsu Saito; Satoshi Shizuta; Koh Ono; Kaori Togashi; Takeshi Kimura

  The international journal of cardiovascular imaging, Feb. 2017, Peer-reviewed

  
• Significant association of RNF213 p.R4810K, a moyamoya susceptibility variant, with coronary artery disease.

  Takaaki Morimoto; Yohei Mineharu; Koh Ono; Masahiro Nakatochi; Sahoko Ichihara; Risako Kabata; Yasushi Takagi; Yang Cao; Lanying Zhao; Hatasu Kobayashi; Kouji H Harada; Katsunobu Takenaka; Takeshi Funaki; Mitsuhiro Yokota; Tatsuaki Matsubara; Ken Yamamoto; Hideo Izawa; Takeshi Kimura; Susumu Miyamoto; Akio Koizumi

  PloS one, 2017, Peer-reviewed

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• Prevention of neointimal formation using miRNA-126-containing nanoparticle-conjugated stents in a rabbit model.

  Masayasu Izuhara; Yasuhide Kuwabara; Naritatsu Saito; Erika Yamamoto; Daihiko Hakuno; Yasuhiro Nakashima; Takahiro Horie; Osamu Baba; Masataka Nishiga; Tetsushi Nakao; Tomohiro Nishino; Fumiko Nakazeki; Yuya Ide; Masahiro Kimura; Takeshi Kimura; Koh Ono

  PloS one, 2017, Peer-reviewed

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• Cardiac and Noncardiac Causes of Long-Term Mortality in ST-Segment-Elevation Acute Myocardial Infarction Patients Who Underwent Primary Percutaneous Coronary Intervention.

  Yugo Yamashita; Hiroki Shiomi; Takeshi Morimoto; Hidenori Yaku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Mitsuru Abe; Kazuya Nagao; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  Circulation. Cardiovascular quality and outcomes, Jan. 2017, Peer-reviewed

  
• A Novel Link between Plasma MicroRNA-33b Levels and Lipid Disorders in Diabetes Mellitus.

  Koh Ono

  Journal of atherosclerosis and thrombosis, 01 Nov. 2016, Peer-reviewed

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• MicroRNA-Linked Heart Disease and Therapeutic Potential

  K. Ono

  Translating MicroRNAs to the Clinic, 29 Sep. 2016, Peer-reviewed

  
• MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development.

  Yuji Eso; Atsushi Takai; Tomonori Matsumoto; Tadashi Inuzuka; Takahiro Horie; Koh Ono; Shinji Uemoto; Kyeryoung Lee; Winfried Edelmann; Tsutomu Chiba; Hiroyuki Marusawa

  Cancer research, 01 Aug. 2016, Peer-reviewed

  
• Effects of Age and Sex on Clinical Outcomes After Percutaneous Coronary Intervention Relative to Coronary Artery Bypass Grafting in Patients With Triple-Vessel Coronary Artery Disease.

  Kyohei Yamaji; Hiroki Shiomi; Takeshi Morimoto; Kenji Nakatsuma; Toshiaki Toyota; Koh Ono; Yutaka Furukawa; Yoshihisa Nakagawa; Kazushige Kadota; Kenji Ando; Shinichi Shirai; Tomoya Onodera; Hirotoshi Watanabe; Masahiro Natsuaki; Ryuzo Sakata; Michiya Hanyu; Noboru Nishiwaki; Tatsuhiko Komiya; Takeshi Kimura

  Circulation, 10 May 2016, Peer-reviewed

  
• 開心術をうけた心血管患者血清と心嚢水におけるマイクロRNA423‐5pの発現

  宇佐美俊輔; 宮本昌一; 桑原康秀; 堀江貴裕; 馬場理; 伯野大彦; 中島康弘; 西賀雅隆; 出原正康; 中尾哲史; 西野共達; 井手裕也; 中関典子; 木村昌弘; 花田律子; 植山浩二; 木村剛; 尾野亘

  血管, 31 Jan. 2016

  
• マイクロRNA‐33を介した新たな脂質代謝制御機構の解明

  堀江貴裕; 西野共達; 馬場理; 桑原康秀; 木村剛; 尾野亘

  血管, 31 Jan. 2016

  
• 動脈硬化症の分子メカニズム microRNAと動脈硬化症

  尾野亘

  臨床化学, 29 Jan. 2016

  
• Elevated Adiponectin Antibody Levels in Sera of Patients with Atherosclerosis-Related Coronary Artery Disease, Cerebral Infarction and Diabetes Mellitus.

  Hiwasa T; Zhang XM; Kimura R; Ohno M; Chen PM; Nishi E; Ono K; Kimura T; Kamitsukasa I; Wada T; Aotsuka A; Mine S; Takizawa H; Kashiwado K; Takemoto M; Kobayashi K; Kawamura H; Ishibashi R; Yokote K; Nakamura R; Tomiyoshi G; Shinmen N; Kuroda H

  Journal of circulating biomarkers, Jan. 2016, Peer-reviewed

  
• Emerging Novel Biomarkers for Arteriosclerosis Obliterans.

  Takahiro Horie; Takeshi Kimura; Koh Ono

  Journal of atherosclerosis and thrombosis, 2016, Peer-reviewed

  
• Functions of microRNA-33a/b and microRNA therapeutics.

  Koh Ono

  Journal of cardiology, Jan. 2016, Peer-reviewed

  
• Adaptive servoventilation versus oxygen therapy for sleep disordered breathing in patients with heart failure: a randomised trial.

  Murase K; Ono K; Yoneda T; Iguchi M; Yokomatsu T; Mizoguchi T; Izumi T; Akao M; Miki S; Nohara R; Ueshima K; Mishima M; Kimura T; White DP; Chin K

  Open heart, 2016, Peer-reviewed

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• マイクロRNAと転写因子相互作用による脂質代謝制御

  尾野亘

  生化学, 25 Dec. 2015

  
• Influence of Sex on Long-Term Outcomes After Implantation of Bare-Metal Stent: A Multicenter Report From the Coronary Revascularization Demonstrating Outcome Study-Kyoto (CREDO-Kyoto) Registry Cohort-1.

  Kyohei Yamaji; Hiroki Shiomi; Takeshi Morimoto; Toshiaki Toyota; Koh Ono; Yutaka Furukawa; Yoshihisa Nakagawa; Kazushige Kadota; Kenji Ando; Shinichi Shirai; Masayuki Kato; Yoshiki Takatsu; Osamu Doi; Hirofumi Kambara; Satoru Suwa; Tomoya Onodera; Hirotoshi Watanabe; Masahiro Natsuaki; Takeshi Kimura

  Circulation, 15 Dec. 2015, Peer-reviewed

  
• ncRNA研究と疾患,診断,創薬 2.生活習慣病とmiRNA―miRNA‐33a/bの生理機能

  尾野亘

  実験医学, 10 Dec. 2015

  
• [Regulation of lipid metabolism by miRNAs and transcription factors].

  Koh Ono

  Seikagaku. The Journal of Japanese Biochemical Society, Dec. 2015, Peer-reviewed

  
• Serum HDL Cholesterol Decreases in Microrna-33b Knock-in Mice for an Intron of Sterol Regulatory Element-binding Factor 1 (Srebf1)

  Hone Takahiro; Nishino Tomohiro; Baba Osamu; Kuwabara Yasuhide; Nakao Tetsushi; Nishiga Masataka; Usami Shunsuke; Izuhara Masayasu; Nakazeki Fumiko; Ide Yuya; Koyama Satoshi; Sowa Naoya; Nakashima Yasuhiro; Hakuno Daihiko; Kimura Takeshi; Ono Koh

  CIRCULATION, 10 Nov. 2015, Peer-reviewed

  
• microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain.

  Jaekwang Kim; Hyejin Yoon; Takahiro Horie; Jack M Burchett; Jessica L Restivo; Noemi Rotllan; Cristina M Ramírez; Philip B Verghese; Masafumi Ihara; Hyang-Sook Hoe; Christine Esau; Carlos Fernández-Hernando; David M Holtzman; John R Cirrito; Koh Ono; Jungsu Kim

  The Journal of neuroscience : the official journal of the Society for Neuroscience, 04 Nov. 2015, Peer-reviewed

  
• High-density lipoprotein cholesterol levels and cardiovascular outcomes in Japanese patients after percutaneous coronary intervention: a report from the CREDO-Kyoto registry cohort-2.

  Masayasu Izuhara; Koh Ono; Hiroki Shiomi; Takeshi Morimoto; Yutaka Furukawa; Yoshihisa Nakagawa; Satoshi Shizuta; Tomohisa Tada; Junichi Tazaki; Takahiro Horie; Yasuhide Kuwabara; Osamu Baba; Tomohiro Nishino; Toru Kita; Takeshi Kimura

  Atherosclerosis, Oct. 2015, Peer-reviewed

  
• 動脈硬化研究の新展開―未知の治療ターゲットを求めて 心血管疾患の新規治療標的としてのmiR‐33a/b

  尾野亘

  循環器専門医, 25 Sep. 2015

  
• Noninvasive Detection of Functional Myocardial Ischemia: Multifunction Cardiogram Evaluation in Diagnosis of Functional Coronary Ischemia Study (MED-FIT).

  Tetsuma Kawaji; Hiroki Shiomi; Takeshi Morimoto; Ryusuke Nishikawa; Mariko Yano; Hirooki Higami; Junichi Tazaki; Masao Imai; Naritatsu Saito; Takeru Makiyama; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, Sep. 2015, Peer-reviewed

  
• 心不全に対する多面的治療戦略―基礎から臨床へ―マイクロRNA制御による心不全治療

  尾野亘

  循環器内科, 28 Aug. 2015

  
• Serum HDL-C Decreases in MicroRNA-33b Knock-in Mice for an Intron of Sterol Regulatory Element-binding Factor 1 (Srebf1)

  Horie Takahiro; Nishino Tomohiro; Kuwabara Yasuhide; Baba Osamu; Kimura Takeshi; Ono Koh

  CIRCULATION RESEARCH, 17 Jul. 2015, Peer-reviewed

  
• Long-term clinical outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease.

  Hirooki Higami; Hiroki Shiomi; Shunichiro Niki; Junichi Tazaki; Masao Imai; Naritatsu Saito; Takeru Makiyama; Satoshi Shizuta; Tetsuo Shioi; Koh Ono; Takeshi Kimura

  Cardiovascular intervention and therapeutics, Jul. 2015, Peer-reviewed

  
• Long-Term Outcomes After Coronary Stent Implantation in Patients Presenting With Versus Without Acute Myocardial Infarction (an Observation from Coronary Revascularization Demonstrating Outcome Study-Kyoto Registry Cohort-2).

  Kyohei Yamaji; Masahiro Natsuaki; Takeshi Morimoto; Koh Ono; Yutaka Furukawa; Yoshihisa Nakagawa; Kazushige Kadota; Kenji Ando; Shinichi Shirai; Hirotoshi Watanabe; Hiroki Shiomi; Takeshi Kimura

  The American journal of cardiology, 01 Jul. 2015, Peer-reviewed

  
• Srebf1のイントロンにmicroRNA‐33bをノックインしたマウスはHDLコレステロールの減少を示す

  堀江貴裕; 西野共達; 馬場理; 桑原康秀; 中尾哲史; 西賀雅隆; 宇佐美俊輔; 出原正康; 島野仁; 横出正之; 北徹; 木村剛; 尾野亘

  日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), 25 Jun. 2015

  
• microRNAと循環器疾患

  尾野亘

  循環器内科, 28 Apr. 2015

  
• microRNA‐33a/bによる細胞・臓器レベルの脂質代謝制御機構

  尾野亘; 堀江貴裕; 西野共達; 木村剛

  糖尿病, 25 Apr. 2015

  
• 睡眠呼吸障害を有する心不全患者への夜間酸素療法vs ASV療法の無作為化比較試験

  村瀬公彦; 尾野亘; 赤尾昌治; 三木真司; 野原隆司; 木村剛; 三嶋理晃; 陳和夫

  日本内科学会雑誌, 20 Feb. 2015

  
• イントロンに存在するmicroRNA‐33aおよび33bとそのホスト遺伝子SREBP2およびSREBP1間の脂質代謝クロストークの解明

  堀江貴裕; 尾野亘; 木村剛; 横出正之

  医科学応用研究財団研究報告(CD-ROM), Feb. 2015

  
• miR‐33a/bによる細胞・臓器レベルの脂質代謝制御機構

  尾野亘; 堀江貴裕; 西野共達; 北徹, 木村剛

  血管, 31 Jan. 2015

  
• Validation of Multifunction CardioGram (MCG) in screening of Coronary Atherosclerosis

  川治徹真; 塩見紘樹; 西川隆介; 矢野真理子; 樋上裕起; 田崎淳一; 今井逸雄; 斎藤成達; 牧山武; 静田聡; 尾野亘; 木村剛

  臨床医薬, 30 Jan. 2015

  
• MicroRNA-451 exacerbates lipotoxicity in cardiac myocytes and high-fat diet-induced cardiac hypertrophy in mice through suppression of the LKB1/AMPK pathway.

  Yasuhide Kuwabara; Takahiro Horie; Osamu Baba; Shin Watanabe; Masataka Nishiga; Shunsuke Usami; Masayasu Izuhara; Tetsushi Nakao; Tomohiro Nishino; Kinya Otsu; Toru Kita; Takeshi Kimura; Koh Ono

  Circulation research, 16 Jan. 2015, Peer-reviewed

  
• Clinical impact of left ventricular outflow tract obstruction in takotsubo cardiomyopathy.

  Tetsuma Kawaji; Hiroki Shiomi; Takeshi Morimoto; Junichi Tazaki; Masao Imai; Naritatsu Saito; Takeru Makiyama; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 2015, Peer-reviewed

  
• MicroRNA-133a in the Development of Arteriosclerosis Obliterans.

  Koh Ono

  Journal of atherosclerosis and thrombosis, 2015, Peer-reviewed

  
• MicroRNA-33a/b in lipid metabolism – novel “thrifty” models.

  Koh Ono; Takahiro Horie; Tomohiro Nishino; Osamu Baba; Yasuhide Kuwabara; Masayuki Yokode; Toru Kita; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 2015, Peer-reviewed

  
• MicroRNAs and High-Density Lipoprotein Cholesterol Metabolism.

  Koh Ono; Takahiro Horie; Tomohiro Nishino; Osamu Baba; Yasuhide Kuwabara; Takeshi Kimura

  International heart journal, 2015, Peer-reviewed

  
• Expression Patterns of miRNA-423-5p in the Serum and Pericardial Fluid in Patients Undergoing Cardiac Surgery.

  Shoichi Miyamoto; Shunsuke Usami; Yasuhide Kuwabara; Takahiro Horie; Osamu Baba; Daihiko Hakuno; Yasuhiro Nakashima; Masataka Nishiga; Masayasu Izuhara; Tetsushi Nakao; Tomohiro Nishino; Yuya Ide; Fumiko Nakazeki; Jun Wang; Koji Ueyama; Takeshi Kimura; Koh Ono

  PloS one, 2015, Peer-reviewed

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• microRNAs and Cardiovascular Remodeling.

  Koh Ono

  Advances in experimental medicine and biology, 2015, Peer-reviewed

  
• 肺胞蛋白症に肺高血圧症を合併した一例

  北野一樹; 木下秀之; 谷澤公伸; 大原弘喜; 辰島正二郎; 山田千夏; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 気腫合併肺線維症に合併した高度肺高血圧に対し肺血管拡張療法を行った1症例

  岡林真梨恵; 木下秀之; 相澤卓範; 半田知宏; 室繁郎; 山田千夏; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 血液透析施行中の末期腎不全に合併した肺高血圧症に対し肺血管拡張薬を投与した1症例

  家村知樹; 山田千夏; 木下秀之; 辰島正二郎; 小笹寧子; 渡部宏俊; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 胸痛に対して緊急カテーテルを施行し非定型的なたこつぼ型心筋症を認めた一例

  相澤卓範; 田崎淳一; 今井逸雄; 齋藤成達; 藤田啓誠; 静田聡; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 非アルコール性脂肪肝炎に合併したと考えられる門脈圧亢進症性肺動脈性肺高血圧症の1症例

  辰島正二郎; 木下秀之; 柳沢洋; 川治徹真; 山田千夏; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 肺移植待機中の肺動脈性肺高血圧症患者における予後予測指標の検討

  山上新太郎; 木下秀之; 本山秀樹; 土屋恭子; 青山晃博; 陳豊史; 辻村郎; 柳澤洋; 山田千夏; 牧山武; 中川靖章; 靜田聡; 桑原宏一郎; 尾野亘; 伊達洋至; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 僧帽弁逆流の成因解明にストレインエコーが有用であった心サルコイドーシスの1症例

  米田智也; 木下秀之; 相澤卓範; 岡林真梨恵; 中島康弘; 山田千夏; 今井逸雄; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 一山智; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• SREBP1のイントロンに存在するmiR‐33bはHDLコレステロールを減少させる

  堀江貴裕; 西野共達; 馬場理; 桑原康秀; 中尾哲史; 西賀雅隆; 宇佐美俊輔; 出原正康; 中関典子; 井手裕也; 小山智史; 曽和尚也; 矢作直也; 島野仁; 横出正之; 北徹; 木村剛; 尾野亘

  日本血管生物医学会学術集会プログラム・抄録集, 2015

  
• マウス大動脈縮窄モデルにより増加するlincRNAはマウス心筋細胞において心肥大を誘導する

  桑原康秀; 桑原康秀; 堀江貴裕; 馬場理; 出原正康; 宇佐美俊輔; 西賀雅隆; 西野共達; 北徹; 木村剛; 尾野亘

  日本心不全学会学術集会プログラム・抄録集, 2015

  
• マイクロRNAの局所徐放化による新規血管治療法の開発

  尾野亘; 出原正康

  先進医薬研究振興財団 2014年度 研究成果報告集, 2015

  
• 血中自己抗体検出と新規炎症マーカーを用いた急性冠症候群予知因子および治療標的の探索―急性冠症候群バイオマーカーとしてのマイクロRNAの可能性について―

  尾野亘

  血中自己抗体検出と新規炎症マーカーを用いた急性冠症候群予知因子および治療標的の探索 平成26年度 総括・分担研究報告書, 2015

  
• SREBPのイントロン性マイクロRNAの生体における脂質代謝機構の包括的解明

  堀江貴裕; 尾野亘; 木村剛; 横出正之

  先進医薬研究振興財団 2014年度 研究成果報告集, 2015

  
• 2型糖尿病を併せ持つ高血圧患者におけるメトホルミンの心肥大・心機能に対する効果の検討(ABLE‐MET)に関する研究の立ち上げ

  尾野亘; 尾野亘; 森利依子; 和田啓道; 浅原哲子; 藤田正俊; 島津章; 長谷川浩二

  国立病院総合医学会抄録集(CD-ROM), 2015

  
• ワルファリン及びエドキサバンに不耐性を示した再発性深部静脈血栓症(DVT)にアピキサバンを使用した一例

  池田圭佑; 杉山裕章; 今井逸雄; 牧山武; 齋藤成達; 木下秀之; 静田聡; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 心房細動に対する冷凍アブレーションが奏功した一例~当院における初期40症例の治療成績とともに~

  ホームズ彩乃; 杉山裕章; 静田聡; 的場芳樹; 川治徹真; 中井健太郎; 牧山武; 齋藤成達; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 原因不明の左心機能低下を背景に持ち,心室細動から蘇生した1症例

  水野良祐; 岡林真梨恵; 川治徹真; 田崎淳一; 齋藤成達; 静田聡; 牧山武; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 好酸球増多症に伴う血管炎により難治性足趾潰瘍を生じた一例

  相澤卓範; 樋上裕起; 田崎淳一; 今井逸雄; 齋藤成達; 静田聡; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 若年で大動脈解離を繰り返し発症した遺伝性大動脈疾患が疑われる1例

  森田悠吾; 樋上裕起; 田崎淳一; 齋藤成達; 静田聡; 南方謙二; 坂田隆造; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 肺高血圧症を早期に発見できた間質性肺炎合併多発性筋炎の1症例

  脊古裕太; 木下秀之; 柳沢洋; 藤井隆夫; 半田知宏; 山田千夏; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• 持続性心房細動に対してNifekalantを用いたCFAEアブレーションが有効であった一例

  川治徹真; 八幡光彦; 中井健太郎; 牧山武; 静田聡; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• ICD移植後,頻回のVF,ICD作動が起こった若年J波症候群の一例

  橋本健太郎; 八幡光彦; 岡林真梨恵; 辰島正二郎; 藤田啓誠; 笹智樹; 柳沢洋; 川治徹真; 樋上裕起; 塩見紘樹; 中井健太郎; 渡部宏俊; 田崎淳一; 杉山裕章; 今井逸雄; 齋藤成達; 牧山武; 土井孝浩; 静田聡; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• Sjogren症候群に伴う自律神経障害に対しステロイド治療が奏功した1症例

  辰島正二郎; 桑原宏一郎; 木下秀之; 石村拓也; 秋月修治; 湯川尚一郎; 藤井隆夫; 樋上裕起; 山田千夏; 中川靖章; 静田聡; 尾野亘; 三森経世; 木村剛

  日本循環器学会近畿地方会(Web), 2015

  
• Effect of statin therapy on cardiovascular outcomes after coronary revascularization in patients ≥ 80 years of age: observations from the CREDO-Kyoto Registry Cohort-2.

  Masahiro Natsuaki; Takeshi Morimoto; Yutaka Furukawa; Hiroki Shiomi; Koh Ono; Takeshi Kimura

  Atherosclerosis, Dec. 2014, Peer-reviewed

  
• Microrna-33, Located Within Srebf2 Intron, Regulate Fatty Acid Synthesis via Targeting SREBP-1 in vivo

  Nishino Tomohiro; Hone Takahiro; Baba Osamu; Kuwabara Yasuhide; Nakao Tetsushi; Nishiga Masataka; Usami Shunsuke; Izuhara Masayasu; Ide Yuya; Nakazeki Fumiko; Koyama Satoshi; Yokode Masayuki; Kita Toru; Kimura Takeshi; Ono Koh

  CIRCULATION, 25 Nov. 2014, Peer-reviewed

  
• Effect of preinfarction angina pectoris on long-term survival in patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention.

  Tomohiko Taniguchi; Hiroki Shiomi; Toshiaki Toyota; Takeshi Morimoto; Masaharu Akao; Kenji Nakatsuma; Koh Ono; Takeru Makiyama; Satoshi Shizuta; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Minoru Horie; Takeshi Kimura

  The American journal of cardiology, 15 Oct. 2014, Peer-reviewed

  
• 最新コレステロール代謝調節研究 マイクロRNAによる脂肪酸・コレステロールの制御機構

  尾野亘

  Bio Ind, 12 Sep. 2014

  
• Incidence and outcome of surgical procedures after coronary artery bypass grafting compared with those after percutaneous coronary intervention: a report from the Coronary Revascularization Demonstrating Outcome Study in Kyoto PCI/CABG Registry Cohort-2.

  Akihiro Tokushige; Hiroki Shiomi; Takeshi Morimoto; Koh Ono; Yutaka Furukawa; Yoshihisa Nakagawa; Kazushige Kadota; Kenji Ando; Satoshi Shizuta; Tomohisa Tada; Junichi Tazaki; Yoshihiro Kato; Mamoru Hayano; Mitsuru Abe; Shuichi Hamasaki; Mitsuru Ohishi; Hitoshi Nakashima; Kazuaki Mitsudo; Masakiyo Nobuyoshi; Toru Kita; Yutaka Imoto; Ryuzo Sakata; Hitoshi Okabayashi; Michiya Hanyu; Mitsuomi Shimamoto; Noboru Nishiwaki; Tatsuhiko Komiya; Takeshi Kimura

  Circulation. Cardiovascular interventions, Aug. 2014, Peer-reviewed

  
• HDL機能と病態・創薬 II.HDLを標的とした動脈硬化性疾患治療の現状と未来 5.miRNA‐33

  尾野亘

  Lipid, 10 Jul. 2014

  
• Anticoagulant and antiplatelet therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention.

  Koji Goto; Kentaro Nakai; Satoshi Shizuta; Takeshi Morimoto; Hiroki Shiomi; Masahiro Natsuaki; Mitsuhiko Yahata; Chihiro Ota; Koh Ono; Takeru Makiyama; Yoshihisa Nakagawa; Yutaka Furukawa; Kazushige Kadota; Yoshiki Takatsu; Takashi Tamura; Akinori Takizawa; Tsukasa Inada; Osamu Doi; Ryuji Nohara; Mitsuo Matsuda; Teruki Takeda; Masayuki Kato; Manabu Shirotani; Hiroshi Eizawa; Katsuhisa Ishii; Jong-Dae Lee; Masaaki Takahashi; Minoru Horie; Mamoru Takahashi; Shinji Miki; Takeshi Aoyama; Satoru Suwa; Shuichi Hamasaki; Hisao Ogawa; Kazuaki Mitsudo; Masakiyo Nobuyoshi; Toru Kita; Takeshi Kimura

  The American journal of cardiology, 01 Jul. 2014, Peer-reviewed

  
• microRNA‐33の動脈硬化・脂質制御における役割

  尾野亘; 堀江貴裕; 桑原康秀; 馬場理; 西野共達; 久米典昭; 横出正之; 北徹, 木村剛

  日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), 25 Jun. 2014

  
• マイクロRNA‐33による脂質代謝制御機構の解明

  堀江貴裕; 桑原康秀; 馬場理; 西野共達; 中尾哲史; 西賀雅隆; 宇佐美俊輔; 出原正康; 矢作直也; 島野仁; 横出正之; 北徹; 木村剛; 尾野亘

  日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), 25 Jun. 2014

  
• MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo.

  Takahiro Horie; Tomohiro Nishino; Osamu Baba; Yasuhide Kuwabara; Tetsushi Nakao; Masataka Nishiga; Shunsuke Usami; Masayasu Izuhara; Fumiko Nakazeki; Yuya Ide; Satoshi Koyama; Naoya Sowa; Naoya Yahagi; Hitoshi Shimano; Tomoyuki Nakamura; Koji Hasegawa; Noriaki Kume; Masayuki Yokode; Toru Kita; Takeshi Kimura; Koh Ono

  Scientific reports, 16 Jun. 2014, Peer-reviewed

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• Evolution in practice patterns and long-term outcomes of coronary revascularization from bare-metal stent era to drug-eluting stent era in Japan.

  Hiroki Shiomi; Takeshi Morimoto; Takeru Makiyama; Koh Ono; Yutaka Furukawa; Yoshihisa Nakagawa; Kazushige Kadota; Tomoya Onodera; Yoshiki Takatsu; Kazuaki Mitsudo; Toru Kita; Ryuzo Sakata; Hitoshi Okabayashi; Michiya Hanyu; Tatsuhiko Komiya; Fumio Yamazaki; Noboru Nishiwaki; Takeshi Kimura

  The American journal of cardiology, 15 May 2014, Peer-reviewed

  
• PROGNOSTIC IMPACT OF THE STAGED PERCUTANEOUS CORONARY INTERVENTION STRATEGY FOR NON-CULPRIT LESIONS IN ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION PATIENTS WITH MULTI-VESSEL DISEASE UNDERGOING PRIMARY PERCUTANEOUS CORONARY INTERVENTION

  Toshiaki Toyota; Hiroki Shiomi; Tomohiko Taniguchi; Kenji Nakatsuma; Hiroki Watanabe; Koh Ono; Satoshi Shizuta; Takeru Makiyama; Yoshihisa Nakagawa; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Minoru Horie; Takeshi Kimura

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Apr. 2014, Peer-reviewed

  
• 基礎科学の進歩 microRNAと循環器疾患

  尾野亘

  循環器専門医, 25 Mar. 2014

  
• Myocardial expression level of neural cell adhesion molecule correlates with reduced left ventricular function in human cardiomyopathy.

  Kazuya Nagao; Naoya Sowa; Katsumi Inoue; Motoko Tokunaga; Kohei Fukuchi; Koji Uchiyama; Haruyasu Ito; Fujio Hayashi; Toshinori Makita; Tsukasa Inada; Masaru Tanaka; Takeshi Kimura; Koh Ono

  Circulation. Heart failure, 01 Mar. 2014, Peer-reviewed

  
• Seeing is believing - Imaging of a plaque in the renal artery.

  Koh Ono

  Journal of cardiology cases, Feb. 2014, Peer-reviewed

  
• 致死性不整脈症候群の病態解明に関する研究―臨床・基礎研究(ヒト疾患特異的人工多能性幹(iPS)細胞を用いた解析)

  木村剛; 北徹; 堀江稔; 堀内久徳; 尾野亘; 牧山武; 吉田善紀

  医科学応用研究財団研究報告(CD-ROM), Feb. 2014

  
• 循環器の生物学 6.代謝と循環器疾患に関わるmicroRNA

  尾野亘

  Annual Review 循環器, 25 Jan. 2014

  
• MicroRNAs and Lipoprotein Metabolism.

  Takahiro Horie; Osamu Baba; Yasuhide Kuwabara; Masayuki Yokode; Toru Kita; Takeshi Kimura; Koh Ono

  Journal of atherosclerosis and thrombosis, 2014, Peer-reviewed

  
• Long-term efficacy and safety outcomes after unrestricted use of drug-eluting stents in patients with acute coronary syndrome: mortality and major bleeding in a single-center registry.

  Tetsuma Kawaji; Hiroki Shiomi; Takeshi Morimoto; Toshihiro Tamura; Ryusuke Nishikawa; Mariko Yano; Junichi Tazaki; Masao Imai; Naritatsu Saito; Takeru Makiyama; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 2014, Peer-reviewed

  
• Cardiac-specific inhibition of kinase activity in calcium/calmodulin-dependent protein kinase kinase-β leads to accelerated left ventricular remodeling and heart failure after transverse aortic constriction in mice.

  Shin Watanabe; Takahiro Horie; Kazuya Nagao; Yasuhide Kuwabara; Osamu Baba; Hitoo Nishi; Naoya Sowa; Michiko Narazaki; Tetsuya Matsuda; Genzou Takemura; Hiromichi Wada; Koji Hasegawa; Takeshi Kimura; Koh Ono

  PloS one, 2014, Peer-reviewed

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• 2型糖尿病を併せ持つ高血圧患者におけるメトホルミンの心肥大・心機能に対する効果の検討(ABLE‐MET)に関する研究の立ち上げ

  尾野亘; 森利依子; 和田啓道; 浅原哲子; 藤田正俊; 島津章; 長谷川浩二

  国立病院総合医学会抄録集(CD-ROM), 2014

  
• Srebf1のイントロンにmicroRNA‐33bをノックインしたマウスはHDLコレステロールの減少を示す

  堀江貴裕; 西野共達; 馬場理; 桑原康秀; 中尾哲史; 西賀雅隆; 宇佐美俊輔; 出原正康; 井手裕也; 中関典子; 小山智史; 曽和尚也; 木村剛; 尾野亘

  日本分子生物学会年会プログラム・要旨集(Web), 2014

  
• 左心耳(LAA)血栓の存在評価に腹臥位心臓CTが有用であった一例

  岡林真梨恵; 杉山裕章; 静田聡; 金尾昌太郎; 桑原康秀; 山田千夏; 牧山武; 齋藤成達; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2014

  
• 膠原病関連肺高血圧症に対する早期発見による肺血管拡張薬治療効果の検討

  柳澤洋; 木下秀之; 山田千夏; 桑原佳宏; 中川靖章; 牧山武; 静田聡; 尾野亘; 塩井哲雄; 桑原宏一郎; 木村剛

  日本循環器学会近畿地方会(Web), 2014

  
• 血中自己抗体検出と新規炎症マーカーを用いた急性冠症候群予知因子および治療標的の探索―急性冠症候群バイオマーカーとしてのマイクロRNAの可能性について―

  尾野亘

  血中自己抗体検出と新規炎症マーカーを用いた急性冠症候群予知因子および治療標的の探索 平成25年度 総括・分担研究報告書, 2014

  
• 全身性強皮症に合併した肺高血圧症に対し原因の鑑別を行った1症例

  脊古裕太; 木下秀之; 山田千夏; 中川靖章; 静田聡; 尾野亘; 塩井哲雄; 桑原宏一郎; 木村剛

  日本循環器学会近畿地方会(Web), 2014

  
• 飽和脂肪酸により誘導されるmicroRNA‐451は,糖尿病性心筋症の増悪因子である

  桑原康秀; 堀江貴裕; 馬場理; 出原正康; 宇佐美俊輔; 中尾哲史; 西賀雅隆; 西野共達; 井手裕也; 中関典子; 小山智史; 木村剛; 尾野亘

  日本分子生物学会年会プログラム・要旨集(Web), 2014

  
• 心室二重応答を介して房室リエントリー性頻拍(AVRT)が誘発された顕在性WPW症候群の一例

  相澤卓範; 杉山裕章; 静田聡; 牧山武; 齋藤成達; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2014

  
• マイクロRNA‐33は,生体内においてSREBP‐1を介して脂肪酸代謝を制御する

  西野共達; 堀江貴裕; 馬場理; 桑原康秀; 中尾哲史; 西賀雅隆; 宇佐美俊輔; 出原正康; 中関典子; 井手裕也; 小山智史; 曽和尚也; 木村剛; 尾野亘

  日本分子生物学会年会プログラム・要旨集(Web), 2014

  
• 強皮症関連肺動脈性肺高血圧における膵癌術後に発症した急性呼吸不全に対しステロイド治療が奏功した1症例

  勝島將夫; 木下秀之; 岸森建文; 岡野嘉明; 山田千夏; 中川靖章; 田崎淳一; 今井逸雄; 静田聡; 尾野亘; 塩井哲雄; 桑原宏一郎; 木村剛

  日本循環器学会近畿地方会(Web), 2014

  
• Becker型筋ジストロフィ合併拡張型心筋症

  川治徹真; 今井逸雄; 小笹寧子; 齋藤成達; 牧山武; 静田聡; 尾野亘; 塩井哲雄; 木村剛; 中根武一郎; 南方謙二; 坂田隆造

  日本循環器学会近畿地方会(Web), 2014

  
• 先天性右肺動脈欠損を伴う肺高血圧症に僧帽弁逆流症・心房細動を合併し,集学的治療を施行した1例

  笹智樹; 桑原佳宏; 田崎淳一; 木下秀之; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2014

  
• めまいの精査過程で診断された心室頻拍(VT)にカテーテル・アブレーションが有効であった若年女性の一例

  岡田圭次郎; 杉山裕章; 静田聡; 牧山武; 小笹寧子; 井出裕也; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2014

  
• 発作性上室性頻拍(PSVT)に対するカテーテル・アブレーション後に失神で発症した肺血栓塞栓症(PTE)の一例

  小口綾貴子; 杉山裕章; 牧山武; 静田聡; 田崎淳一; 渡部宏俊; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2014

  
• マイクロRNA‐33a/bによる脂質代謝制御機構

  尾野亘

  千里ライフサイエンスセミナー講演要旨集, 2014

  
• LincRNAs Regulated by Pressure-overload Induce Hypertrophy in Neonatal Mouse Ventricular Cardiomyocytes

  Kuwabara Yasuhide; Izuhara Masayasu; Horie Takahiro; Watanabe Shin; Baba Osamu; Usami Shunsuke; Nakao Tetsushi; Nishiga Masataka; Nishino Tomohiro; Kita Toru; Kimura Takeshi; Ono Koh

  CIRCULATION, 26 Nov. 2013, Peer-reviewed

  
• イントロン性マイクロRNA‐33a/bのコレステロール・脂質代謝に対する役割の解明

  尾野亘

  第一三共生命科学研究振興財団研究報告集, 22 Nov. 2013

  
• MicroRNAs and Cardiovascular Diseases

  Koh Ono

  MicroRNAs in Medicine, 04 Nov. 2013, Peer-reviewed

  
• 頸動脈プラークのリスクと対応―プラークの質的診断と適切な治療戦略―頸動脈プラークの治療法 microRNAとプラーク

  尾野亘

  カレントテラピー, 01 Nov. 2013

  
• 分子生物学的検討により動脈硬化を診る HDL‐C標的療法としてのマイクロRNA‐33の抑制の可能性

  尾野亘

  臨床病理, 25 Oct. 2013

  
• [Diagnosis and therapy of atherosclerosis through molecular biological approaches possibility of HDL-targeting therapy by manipulation of micro RNA-33].

  Koh Ono

  Rinsho byori. The Japanese journal of clinical pathology, Oct. 2013, Peer-reviewed

  
• 禁煙後の糖尿病発症予知マーカーとしての可溶性VEGF受容体2レベル

  和田啓道; 浦修一; 浅原啓子; 赤尾昌治; 阿部充; 森本達也; 尾野亘; 島津章; 高橋裕子; 長谷川浩二

  肥満研究, 25 Sep. 2013

  
• Long-term outcomes after percutaneous coronary intervention for chronic total occlusion (from the CREDO-Kyoto registry cohort-2).

  Erika Yamamoto; Masahiro Natsuaki; Takeshi Morimoto; Yutaka Furukawa; Yoshihisa Nakagawa; Koh Ono; Kazuaki Mitsudo; Masakiyo Nobuyoshi; Osamu Doi; Takashi Tamura; Masaru Tanaka; Takeshi Kimura

  The American journal of cardiology, 15 Sep. 2013, Peer-reviewed

  
• うつ状態の指標であるSDSスコアは禁煙失敗の最強の独立規定因子である

  浦修一; 和田啓道; 浅原哲子; 赤尾昌治; 尾野亘; 森本達也; 島津章; 高橋祐子; 長谷川浩二

  日本心臓病学会誌, 09 Sep. 2013

  
• Impact of polyvascular disease on clinical outcomes in patients undergoing coronary revascularization: an observation from the CREDO-Kyoto Registry Cohort-2.

  Yuko Morikami; Masahiro Natsuaki; Takeshi Morimoto; Koh Ono; Yoshihisa Nakagawa; Yutaka Furukawa; Ryuzo Sakata; Masaki Aota; Yukikatsu Okada; Masahiko Onoe; Michio Kawasuji; Takaaki Koshiji; Hiroyuki Nakajima; Junichiro Nishizawa; Kazuo Yamanaka; Hiroyuki Yamamoto; Takeshi Kimura

  Atherosclerosis, Jun. 2013, Peer-reviewed

  
• Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts.

  Yodo Tamaki; Yoshitaka Iwanaga; Shinichiro Niizuma; Tsuneaki Kawashima; Takao Kato; Yasutaka Inuzuka; Takahiro Horie; Hanako Morooka; Toru Takase; Yasumitsu Akahashi; Kazuhiro Kobuke; Koh Ono; Tetsuo Shioi; Søren P Sheikh; Noona Ambartsumian; Eugene Lukanidin; Taka-Aki Koshimizu; Shunichi Miyazaki; Takeshi Kimura

  Journal of molecular and cellular cardiology, Apr. 2013, Peer-reviewed

  
• 低用量アミオダロンの有用性と副作用の検討

  大西尚昭; 静田聡; 太田千尋; 佐々木康博; 八幡光彦; 中井健太郎; 後藤貢士; 土井孝浩; 牧山武; 尾野亘; 塩井哲雄; 木村剛; 貝谷和昭; 泉知里; 中川義久

  Prog Med, 29 Mar. 2013

  
• イントロン性microRNA‐33a/b制御による動脈硬化予防法の開発

  尾野亘

  循環医学研究年報, 21 Mar. 2013

  
• 循環器疾患におけるmicroRNAの働き

  尾野亘

  血管, 31 Jan. 2013

  
• MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice.

  Takahiro Horie; Tomohiro Nishino; Osamu Baba; Yasuhide Kuwabara; Tetsushi Nakao; Masataka Nishiga; Shunsuke Usami; Masayasu Izuhara; Naoya Sowa; Naoya Yahagi; Hitoshi Shimano; Shigenobu Matsumura; Kazuo Inoue; Hiroyuki Marusawa; Tomoyuki Nakamura; Koji Hasegawa; Noriaki Kume; Masayuki Yokode; Toru Kita; Takeshi Kimura; Koh Ono

  Nature communications, 2013, Peer-reviewed

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• Lectin-like oxidized low-density lipoprotein receptor-1 plays an important role in vascular inflammation in current smokers.

  Rieko Takanabe-Mori; Koh Ono; Hiromichi Wada; Tomohide Takaya; Shuichi Ura; Hajime Yamakage; Noriko Satoh-Asahara; Akira Shimatsu; Yuko Takahashi; Masatoshi Fujita; Yoshiko Fujita; Tatsuya Sawamura; Koji Hasegawa

  Journal of atherosclerosis and thrombosis, 2013, Peer-reviewed

  
• Influence of initial acute myocardial infarction presentation on the outcome of surgical procedures after coronary stent implantation: a report from the CREDO-Kyoto PCI/CABG Registry Cohort-2.

  Akihiro Tokushige; Hiroki Shiomi; Takeshi Morimoto; Koh Ono; Yutaka Furukawa; Yoshihisa Nakagawa; Kazushige Kadota; Masashi Iwabuchi; Satoshi Shizuta; Tomohisa Tada; Junichi Tazaki; Yoshihiro Kato; Mamoru Hayano; Mitsuru Abe; Shuichi Hamasaki; Chuwa Tei; Hitoshi Nakashima; Kazuaki Mitsudo; Masakiyo Nobuyoshi; Toru Kita; Takeshi Kimura

  Cardiovascular intervention and therapeutics, Jan. 2013, Peer-reviewed

  
• 両心室ペースメーカー(CRT‐P)植込み後に失神再発を認め,神経調節性失神(NMS)の関与が推察された1例

  辰島正二郎; 杉山裕章; 静田聡; 今井逸雄; 土井孝浩; 八幡光彦; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• 意識消失の精査入院中に心室細動を発症し,埋込型除細動器を移植したJ波症候群の一例

  柳澤洋; 八幡光彦; 土井孝浩; 静田聡; 川治徹真; 西川隆介; 矢野真理子; 樋上裕起; 中井健太郎; 塩見紘樹; 田崎淳一; 杉山裕章; 渡邉真; 今井逸雄; 齋藤成達; 小笹寧子; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• ダビガトラン(DBG)内服時のAPTT過延長を契機に診断された抗リン脂質抗体症候群(APS)の2例

  笹智樹; 杉山裕章; 静田聡; 早野護; 後藤貢士; 中井健太郎; 八幡光彦; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• マイクロRNA制御による動脈硬化治療の探索的研究

  堀江貴裕; 馬場理; 桑原康秀; 久米典昭; 横出正之; 北徹; 木村剛; 尾野亘

  日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), 2013

  
• マイクロRNAのバイオマーカーとしての応用

  尾野亘

  日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), 2013

  
• miRNAと動脈硬化・心不全

  尾野亘; 堀江貴裕; 馬場理; 桑原康秀; 北徹, 木村剛

  日本循環薬理学会口演要旨集, 2013

  
• 非ストレス時に再発性失神発作を認めた先天性QT延長症候群(LQTS)の若年女性の一例

  高華; 杉山裕章; 牧山武; 静田聡; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• 心室頻拍による心肺停止に対して蘇生後,CRT‐Dを移植した不整脈原性右室心筋症の一例

  八幡光彦; 齋藤成達; 川治徹真; 矢野真理子; 西川隆介; 樋上裕起; 中井健太郎; 田崎淳一; 杉山裕章; 今井逸雄; 小笹寧子; 牧山武; 土井孝浩; 静田聡; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• B型大動脈解離にたいして段階的に手術及びステントグラフト内挿術を施行し偽腔の完全血栓化が得られた1例

  田崎淳一; 西川隆介; 樋上裕起; 今井逸雄; 齋藤成達; 牧山武; 尾野亘; 塩井哲雄; 川東正英; 丸井晃; 坂田隆造; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• ペースメーカーデバイス感染症に対しデバイス抜去術が必要となった2症例

  矢野真理子; 八幡光彦; 守上裕子; 土井孝浩; 静田聡; 川治徹真; 西川隆介; 太田千尋; 樋上裕起; 宝蔵麗子; 中井健太郎; 田崎淳一; 今井逸雄; 齋藤成達; 西山慶; 小笹寧子; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• カテコラミン感受性多形性心室頻拍に対し電気生理学検査,植込型除細動器移植術を施行した1例

  北野正之; 八幡光彦; 土井孝浩; 静田聡; 川治徹真; 西川隆介; 矢野真理子; 太田千尋; 樋上裕起; 守上裕子; 宝蔵麗子; 中井健太郎; 田崎淳一; 今井逸雄; 齋藤成達; 西山慶; 小笹寧子; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• Churg‐Strauss症候群において心機能障害をきたした一例

  大久保直紀; 守上裕子; 宝蔵麗子; 塩見紘樹; 夏秋政浩; 渡邉真; 田崎淳一; 今井逸雄; 齋藤成達; 牧山武; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• 循環器疾患におけるバイオマーカーとしての血清中microRNA

  桑原康秀; ガーボルバジョー; 堀江貴裕; 馬場理; 出原正康; 宇佐美俊輔; 中尾哲史; 西賀雅隆; 西野共達; 北徹; 和田啓道; 長谷川浩二; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• 胸部大動脈瘤に対してステントグラフト内挿術施行後に脳塞栓および下肢動脈塞栓を起こした1例

  田崎淳一; 樋上裕起; 西川隆介; 今井逸雄; 齋藤成達; 川東正英; 丸井晃; 坂田隆造; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• 著明な左室流出路圧格差を認めショックに至ったたこつぼ心筋症

  川治徹真; 宝蔵麗子; 今井逸雄; 尾野亘; 塩井哲雄; 牧山武; 静田聡; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• 大動脈弁穿孔を来したベラパミル感受性心室頻拍に対して治療が成功した一例

  八幡光彦; 静田聡; 川治徹真; 西川隆介; 矢野真理子; 太田千尋; 樋上裕起; 守上裕子; 宝蔵麗子; 中井健太郎; 田崎淳一; 今井逸雄; 齋藤成達; 土井孝浩; 西山慶; 小笹寧子; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2013

  
• 疾患エクソソーム:病をもたらすパンドラの箱がいま開かれる【第1部:疾患とエクソソーム】循環器疾患におけるエクソソームの役割

  尾野亘

  細胞工学, 22 Dec. 2012

  
• MicroRNA-33 deficiency reduces the progression of atherosclerotic plaque in ApoE-/- mice.

  Takahiro Horie; Osamu Baba; Yasuhide Kuwabara; Yoshimasa Chujo; Shin Watanabe; Minako Kinoshita; Masahito Horiguchi; Tomoyuki Nakamura; Kazuhisa Chonabayashi; Masakatsu Hishizawa; Koji Hasegawa; Noriaki Kume; Masayuki Yokode; Toru Kita; Takeshi Kimura; Koh Ono

  Journal of the American Heart Association, Dec. 2012, Peer-reviewed

  
• L/T-type and L/N-type calcium-channel blockers attenuate cardiac sympathetic nerve activity in patients with hypertension.

  Chika Ogura; Koh Ono; Shoichi Miyamoto; Akiko Ikai; Satoko Mitani; Naozo Sugimoto; Shiro Tanaka; Masatoshi Fujita

  Blood pressure, Dec. 2012, Peer-reviewed

  
• Highly purified eicosapentaenoic acid increases interleukin-10 levels of peripheral blood monocytes in obese patients with dyslipidemia.

  Noriko Satoh-Asahara; Akira Shimatsu; Yousuke Sasaki; Hidenori Nakaoka; Akihiro Himeno; Mayu Tochiya; Shigeo Kono; Tomohide Takaya; Koh Ono; Hiromichi Wada; Takayoshi Suganami; Koji Hasegawa; Yoshihiro Ogawa

  Diabetes care, Dec. 2012, Peer-reviewed

  
• Current concept of reverse cholesterol transport and novel strategy for atheroprotection.

  Koh Ono

  Journal of cardiology, Nov. 2012, Peer-reviewed

  
• MicroRNA 26b encoded by the intron of small CTD phosphatase (SCP) 1 has an antagonistic effect on its host gene.

  Naoya Sowa; Takahiro Horie; Yasuhide Kuwabara; Osamu Baba; Shin Watanabe; Hitoo Nishi; Minako Kinoshita; Rieko Takanabe-Mori; Hiromichi Wada; Akira Shimatsu; Koji Hasegawa; Takeshi Kimura; Koh Ono

  Journal of cellular biochemistry, Nov. 2012, Peer-reviewed

  
• 動脈硬化研究の新機軸 マイクロRNAと動脈硬化

  尾野亘

  動脈硬化予防, 10 Oct. 2012

  
• コントロール不良高血圧に対するアンジオテンシン2受容体拮抗薬(ARB)単独療法とARB+T型カルシウムチャネル拮抗薬併用療法の効果比較に関する研究(EITHER研究)

  尾野亘; 土肥由裕; 古川裕; 平井忠和; 松本鉄也; 荒井秀典; 木村剛; 藤田正俊

  日本高血圧学会総会プログラム・抄録集, 20 Sep. 2012

  
• 体内リズムと循環器病 8 時計遺伝子と内分泌・代謝―循環器疾患とどうかかわるか―

  尾野亘

  Heart View, 09 Aug. 2012

  
• 動脈硬化進展におけるマイクロRNA‐33の働き

  尾野亘; 堀江貴裕; 馬場理; 久米典昭; 横出正之; 北徹, 木村剛

  日本心臓病学会誌, 06 Aug. 2012

  
• microRNA‐33の動脈硬化形成における役割の検討

  尾野亘; 堀江貴裕; 馬場理; 久米典昭; 横出正之; 北徹, 木村剛

  日本動脈硬化学会総会・学術集会プログラム・抄録集(CD-ROM), 05 Jul. 2012

  
• HDLコレステロールを制御するmicroRNA‐33

  尾野亘

  Bio Clin, 10 Jun. 2012

  
• Impact of statin therapy on late target lesion revascularization after sirolimus-eluting stent implantation (from the CREDO-Kyoto Registry Cohort-2).

  Masahiro Natsuaki; Yoshihisa Nakagawa; Takeshi Morimoto; Koh Ono; Satoshi Shizuta; Yutaka Furukawa; Kazushige Kadota; Masashi Iwabuchi; Yoshihiro Kato; Satoru Suwa; Tsukasa Inada; Osamu Doi; Akinori Takizawa; Masakiyo Nobuyoshi; Toru Kita; Takeshi Kimura

  The American journal of cardiology, 15 May 2012, Peer-reviewed

  
• プラバスタチンもしくはアトルバスタチンとロサルタンの併用が初期心血管病変に及ぼす影響

  和田啓道; 尾野亘; 佐藤哲子; 川村晃久; 森本達也; 上北和実; 東堂龍平; 山田和範; 赤尾昌治; 小坂田元太; 島津章; 長谷川浩二

  糖尿病, 25 Apr. 2012

  
• miRNAと疾患 代謝,循環器のmiRNA

  尾野亘

  月刊メディカル・サイエンス・ダイジェスト, 25 Mar. 2012

  
• マイクロRNA‐33は動脈硬化形成を制御する

  堀江貴裕; 馬場理; 尾野亘; 渡辺真; 西仁勇; 木下美菜子; 桑原康秀; 中條克真; 横出正之; 木村剛

  日本内科学会雑誌, 20 Feb. 2012

  
• microRNA‐33によるHDL代謝調節

  尾野亘

  Annual Review 糖尿病・代謝・内分泌, 30 Jan. 2012

  
• Roles of microRNAs and myocardial cell differentiation.

  Tomohide Takaya; Hitoo Nishi; Takahiro Horie; Koh Ono; Koji Hasegawa

  Progress in molecular biology and translational science, 2012, Peer-reviewed

  
• Intensity of statin therapy, achieved low-density lipoprotein cholesterol levels and cardiovascular outcomes in Japanese patients after coronary revascularization. Perspectives from the CREDO-Kyoto registry cohort-2.

  Masahiro Natsuaki; Yutaka Furukawa; Takeshi Morimoto; Yoshihisa Nakagawa; Koh Ono; Satoshi Kaburagi; Tsukasa Inada; Hirokazu Mitsuoka; Ryoji Taniguchi; Akira Nakano; Toru Kita; Ryuzo Sakata; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 2012, Peer-reviewed

  
• α1-Antitrypsin low-density-lipoprotein serves as a marker of smoking-specific oxidative stress.

  Hiromichi Wada; Shuichi Ura; Noriko Satoh-Asahara; Shuji Kitaoka; Shinichi Mashiba; Masaharu Akao; Mitsuru Abe; Koh Ono; Tatsuya Morimoto; Masatoshi Fujita; Akira Shimatsu; Yuko Takahashi; Koji Hasegawa

  Journal of atherosclerosis and thrombosis, 2012, Peer-reviewed

  
• 上室性頻拍を伴う左房瘤に対して外科的介入をした一例

  川治徹真; 太田千尋; 今井逸雄; 齋藤成達; 土井孝浩; 小笹寧子; 尾野亘; 塩井哲雄; 仲原隆弘; 山崎和裕; 南方謙二; 静田聡; 牧山武; 坂田隆造; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• WPW症候群を合併したEbstein奇形に対し,カテーテルアブレーションを施行した一例

  白神桃子; 八幡光彦; 静田聡; 川治徹真; 西川隆介; 矢野真理子; 太田千尋; 樋上裕起; 守上裕子; 宝蔵麗子; 中井健太郎; 田崎淳一; 今井逸雄; 齋藤成達; 土井孝浩; 西山慶; 小笹寧子; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• 2型糖尿病を併せ持つ高血圧患者におけるメトホルミンの心肥大・心機能に対する効果の検討(ABLE‐MET)に関する研究の立ち上げ

  尾野亘; 森利依子; 和田啓道; 浅原哲子; 藤田正俊; 島津章; 長谷川浩二

  国立病院総合医学会講演抄録集, 2012

  
• 収縮能の保たれた心不全に肺高血圧を合併した一例

  濱谷康弘; 宝蔵麗子; 塩井哲雄; 土井孝浩; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• 心臓再同期療法へのgrade upの際,閉塞した鎖骨下静脈に対する側副血行路を通して左室リードを留置した一例

  八幡光彦; 土井孝浩; 静田聡; 川治徹真; 西川隆介; 矢野真理子; 太田千尋; 樋上裕起; 守上裕子; 宝蔵麗子; 中井健太郎; 田崎淳一; 今井逸雄; 齋藤成達; 西山慶; 小笹寧子; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• 失神を来した閉塞性肥大型心筋症に対しシベンゾリンとペーシングにて左室流出路狭窄の改善を認めた一例

  八幡光彦; 静田聡; 早野護; 太田千尋; 樋上裕起; 大西尚昭; 佐々木康博; 守上裕子; 東谷暢也; 宝蔵麗子; 中井健太郎; 田崎淳一; 今井逸雄; 齋藤成達; 西山慶; 土井孝浩; 小笹寧子; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• 線維筋性異形成に対しPTRAが奏功した一例

  太田千尋; 中井健太郎; 東谷暢也; 守上裕子; 田崎淳一; 今井逸雄; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• 右心不全を来した右室形態異常の一例

  矢野真理子; 守上裕子; 牧山武; 今井逸雄; 土井孝浩; 小笹寧子; 齋藤成達; 静田聡; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• 左心系のMSSA感染性心内膜炎にseptic pulmonary embolismを併発した一例

  川治徹真; 大西尚昭; 尾野亘; 牧山武; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• 慢性心房細動を合併する拡張相肥大型心筋症に対し,アブレーションと心臓再同期療法を施行した一例

  西川隆介; 八幡光彦; 土井孝浩; 静田聡; 川治徹真; 矢野真理子; 太田千尋; 樋上裕起; 守上裕子; 宝蔵麗子; 中井健太郎; 田崎淳一; 今井逸雄; 齋藤成達; 西山慶; 小笹寧子; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• マイクロRNAと脂質異常症

  尾野亘

  Bio Clin, 31 Dec. 2011

  
• MicroRNAと循環器疾患

  尾野亘; 木村剛

  最新医学, 10 Nov. 2011

  
• 線維化による疾患 5 動脈硬化疾患(冠動脈疾患)

  尾野亘; 木村剛

  Bio Clin, 10 Nov. 2011

  
• Bile acid-induced expression of activation-induced cytidine deaminase during the development of Barrett's oesophageal adenocarcinoma.

  Shuko Morita; Yuko Matsumoto; Shunsuke Okuyama; Koh Ono; Yoko Kitamura; Akihisa Tomori; Tsuneo Oyama; Yuji Amano; Yoshikazu Kinoshita; Tsutomu Chiba; Hiroyuki Marusawa

  Carcinogenesis, Nov. 2011, Peer-reviewed

  
• コントロール不良高血圧に対するアンジオテンシンII受容体拮抗薬(ARB)単独療法とARB+T型カルシウムチャネル拮抗薬併用療法の効果比較に関する研究

  尾野亘; 土肥由裕; 古川裕; 平井忠和; 松本鉄也; 荒井秀典; 木村剛; 藤田正俊

  日本高血圧学会総会プログラム・抄録集, 20 Oct. 2011

  
• ポストシークエンス時代の心脈管ゲノミクス 1 Non‐coding RNAと心血管疾患

  尾野亘; 堀江貴裕; 西仁勇; 木下美菜子; 桑原康秀; 馬場理; 木村剛

  血管, 11 Oct. 2011

  
• A case with giant right coronary artery aneurysm in a patient with Behçet's disease.

  Yuko Morigami; Koh Ono; Toshikazu Jinnai; Toshihiro Tamura; Shin Watanabe; Fumie Takai; Hiroaki Osada; Kazuhiro Yamazaki; Toru Kita; Ryuzo Sakata; Takeshi Kimura

  Journal of cardiology cases, Oct. 2011, Peer-reviewed

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• ヒト血中の血管内皮増殖因子A(VEGF‐A)及びC(VEGF‐C)の心血管危険因子との関連

  浦修一; 和田啓道; 北岡修二; 浅原哲子; 高谷智英; 森利依子; 赤尾昌治; 阿部充; 森本達也; 尾野亘; 藤田正俊; 島津章; 長谷川浩二

  肥満研究, 01 Sep. 2011

  
• マイクロRNAと循環器疾患 7)心肥大とマイクロRNA

  西仁勇; 尾野亘; 木村剛

  血管医学, 31 Aug. 2011

  
• マイクロRNAと循環器疾患 マイクロRNA研究の新展開

  尾野亘

  血管医学, 31 Aug. 2011

  
• マイクロRNAと循環器疾患 4)コレステロールホメオスタシスとマイクロRNA

  堀江貴裕; 尾野亘; 横出正之; 木村剛

  血管医学, 31 Aug. 2011

  
• 血管内皮増殖因子Cは動脈硬化惹起性脂質異常と関連している

  浦修一; 和田啓道; 北岡修二; 浅原哲子; 高谷智英; 森利依子; 尾野亘; 赤尾昌治; 阿部充; 森本達也; 藤田正俊; 島津章; 長谷川浩二

  日本心臓病学会誌, 14 Aug. 2011

  
• 2つの酸化LDLマーカーと喫煙との関連の比較

  浦修一; 和田啓道; 浅原哲子; 北岡修二; 赤尾昌治; 阿部充; 尾野亘; 森本達也; 藤田正俊; 島津章; 高橋裕子; 長谷川浩二

  日本心臓病学会誌, 14 Aug. 2011

  
• Increased microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular disease indicate myocardial damage.

  Yasuhide Kuwabara; Koh Ono; Takahiro Horie; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Shin Watanabe; Osamu Baba; Yoji Kojima; Satoshi Shizuta; Masao Imai; Toshihiro Tamura; Toru Kita; Takeshi Kimura

  Circulation. Cardiovascular genetics, 01 Aug. 2011, Peer-reviewed

  
• マイクロRNAとリポ蛋白代謝

  尾野亘; 木村剛

  医学のあゆみ, 25 Jun. 2011

  
• SREBP2のイントロンにコードされるマイクロRNA‐33は生体においてHDLの形成を制御する

  尾野亘

  Ther Res, 20 Jun. 2011

  
• MicroRNA links obesity and impaired glucose metabolism.

  Koh Ono

  Cell research, Jun. 2011, Peer-reviewed

  
• Autophagy limits acute myocardial infarction induced by permanent coronary artery occlusion.

  Hiromitsu Kanamori; Genzou Takemura; Kazuko Goto; Rumi Maruyama; Koh Ono; Kazuya Nagao; Akiko Tsujimoto; Atsushi Ogino; Toshiaki Takeyama; Tomonori Kawaguchi; Takatomo Watanabe; Masanori Kawasaki; Takako Fujiwara; Hisayoshi Fujiwara; Mitsuru Seishima; Shinya Minatoguchi

  American journal of physiology. Heart and circulatory physiology, Jun. 2011, Peer-reviewed

  
• microRNA‐33を介したHDL‐コレステロール調節のあらたなメカニズム

  尾野亘; 木村剛

  医学のあゆみ, 07 May 2011

  
• MicroRNAs and cardiovascular diseases.

  Koh Ono; Yasuhide Kuwabara; Jiahuai Han

  The FEBS journal, May 2011, Peer-reviewed

  
• プラバスタチンもしくはアトルバスタチンとロサルタンの併用が耐糖能患者の初期腎病変に及ぼす影響

  和田啓道; 尾野亘; 浅原(佐藤; 哲子; 川村晃久; 森本達也; 上北和実; 東堂龍平; 山田和範; 赤尾昌治; 小坂田元太; 島津章; 長谷川浩二

  糖尿病, 25 Apr. 2011

  
• Comparison of three-year clinical outcomes after sirolimus-eluting stent implantation among insulin-treated diabetic, non-insulin-treated diabetic, and non-diabetic patients from j-Cypher registry.

  Tomohisa Tada; Takeshi Kimura; Takeshi Morimoto; Koh Ono; Yutaka Furukawa; Yoshihisa Nakagawa; Hitoshi Nakashima; Akira Ito; Nobuo Siode; Masanobu Namura; Naoto Inoue; Hideo Nishikawa; Koichi Nakao; Kazuaki Mitsudo

  The American journal of cardiology, 15 Apr. 2011, Peer-reviewed

  
• MicroRNA-27a regulates beta cardiac myosin heavy chain gene expression by targeting thyroid hormone receptor beta1 in neonatal rat ventricular myocytes.

  Hitoo Nishi; Koh Ono; Takahiro Horie; Kazuya Nagao; Minako Kinoshita; Yasuhide Kuwabara; Shin Watanabe; Tomohide Takaya; Yodo Tamaki; Rieko Takanabe-Mori; Hiromichi Wada; Koji Hasegawa; Yoshitaka Iwanaga; Teruhisa Kawamura; Toru Kita; Takeshi Kimura

  Molecular and cellular biology, Feb. 2011, Peer-reviewed

  
• Impact of diabetes on cardiovascular outcomes in hemodialysis patients undergoing coronary revascularization.

  Masahiro Natsuaki; Yutaka Furukawa; Takeshi Morimoto; Yoshihisa Nakagawa; Masaharu Akao; Koh Ono; Tetsuo Shioi; Satoshi Shizuta; Ryuzo Sakata; Hitoshi Okabayashi; Noboru Nishiwaki; Tatsuhiko Komiya; Satoru Suwa; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 2011, Peer-reviewed

  
• Inter- and intra-observer variability for assessment of the synergy between percutaneous coronary intervention with TAXUS and cardiac surgery (SYNTAX) score and association of the SYNTAX score with clinical outcome in patients undergoing unprotected left main stenting in the real world.

  Hiroki Shiomi; Toshihiro Tamura; Shunichiro Niki; Tomohisa Tada; Junichi Tazaki; Masanao Toma; Koh Ono; Tetsuo Shioi; Takeshi Morimoto; Masaharu Akao; Yutaka Furukawa; Yoshihisa Nakagawa; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, 2011, Peer-reviewed

  
• Distinct characteristics of circulating vascular endothelial growth factor-a and C levels in human subjects.

  Hiromichi Wada; Shuichi Ura; Shuji Kitaoka; Noriko Satoh-Asahara; Takahiro Horie; Koh Ono; Tomohide Takaya; Rieko Takanabe-Mori; Masaharu Akao; Mitsuru Abe; Tatsuya Morimoto; Toshinori Murayama; Masayuki Yokode; Masatoshi Fujita; Akira Shimatsu; Koji Hasegawa

  PloS one, 2011, Peer-reviewed

  
• Cyclin-dependent kinase 9 forms a complex with GATA4 and is involved in the differentiation of mouse ES cells into cardiomyocytes.

  Shinji Kaichi; Tomohide Takaya; Tatsuya Morimoto; Yoichi Sunagawa; Teruhisa Kawamura; Koh Ono; Akira Shimatsu; Shiro Baba; Toshio Heike; Tatsutoshi Nakahata; Koji Hasegawa

  Journal of cellular physiology, Jan. 2011, Peer-reviewed

  
• ルリッシュ症候群の一例

  矢野真理子; 守上祐子; 小笹寧子; 土井孝浩; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2011

  
• 心外膜起源の心室頻拍に対し心外膜アブレーションを施行したサルコイドーシスの1例

  太田千尋; 八幡光彦; 静田聡; 早野護; 樋上裕起; 大西尚昭; 佐々木康博; 守上裕子; 東谷暢也; 宝蔵麗子; 中井健太郎; 徳重明央; 田崎淳一; 今井逸雄; 齋藤成達; 土井孝浩; 小笹寧子; 牧山武; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2011

  
• 心室頻拍にて発症しPETで診断がついた心サルコイドーシスの一例

  熊原加奈; 田崎淳一; 東谷暢也; 八幡光彦; 静田聡; 土井孝浩; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2011

  
• 2型糖尿病を併せ持つ高血圧患者におけるメトホルミンの心肥大・心機能に対する効果の検討(ABLE‐MET)に関する研究の立ち上げ

  尾野亘; 森利依子; 和田啓道; 浅原哲子; 藤田正俊; 島津章; 長谷川浩二

  国立病院総合医学会講演抄録集, 2011

  
• 心不全を契機に診断されたCushing病の1例

  小笹寧子; 曽根正勝; 仁木俊一郎; 酒井健; 尾野亘; 塩井哲雄; 北川雅史; 中尾一和; 宮本享; 木村剛

  Ther Res, 20 Dec. 2010

  
• Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing (vol 1, pg 161, 2010)

  Koh Ono; Xiaofei Wang; Sung Ouk Kim; Lucas C. Armstrong; Paul Bornstein; Jiahuai Han

  PROTEIN & CELL, Dec. 2010, Peer-reviewed

  
• 劇症型心筋炎に急性呼吸窮迫症候群を合併しPCPS・ECMOを使用することで救命に成功した1例

  田崎淳一; 早野護; 多田朋弥; 田村俊寛; 当麻正直; 尾野亘; 古川裕; 北徹; 赤尾昌治; 木村剛

  心臓, 15 Nov. 2010

  
• Insulin-like growth factor axis (insulin-like growth factor-I/insulin-like growth factor-binding protein-3) as a prognostic predictor of heart failure: association with adiponectin.

  Shin Watanabe; Toshihiro Tamura; Koh Ono; Hisanori Horiuchi; Takeshi Kimura; Toru Kita; Yutaka Furukawa

  European journal of heart failure, Nov. 2010, Peer-reviewed

  
• Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice.

  Shinji Kaichi; Koji Hasegawa; Tomohide Takaya; Noritaka Yokoo; Takahiro Mima; Teruhisa Kawamura; Tatsuya Morimoto; Koh Ono; Shiro Baba; Hiraku Doi; Shinya Yamanaka; Tatsutoshi Nakahata; Toshio Heike

  Cardiovascular research, 01 Nov. 2010, Peer-reviewed

  
• MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo.

  Takahiro Horie; Koh Ono; Masahito Horiguchi; Hitoo Nishi; Tomoyuki Nakamura; Kazuya Nagao; Minako Kinoshita; Yasuhide Kuwabara; Hiroyuki Marusawa; Yoshitaka Iwanaga; Koji Hasegawa; Masayuki Yokode; Takeshi Kimura; Toru Kita

  Proceedings of the National Academy of Sciences of the United States of America, 05 Oct. 2010, Peer-reviewed

  
• Regulation of adipocyte differentiation by activation of serotonin (5-HT) receptors 5-HT2AR and 5-HT2CR and involvement of microRNA-448-mediated repression of KLF5.

  Minako Kinoshita; Koh Ono; Takahiro Horie; Kazuya Nagao; Hitoo Nishi; Yasuhide Kuwabara; Rieko Takanabe-Mori; Koji Hasegawa; Toru Kita; Takeshi Kimura

  Molecular endocrinology (Baltimore, Md.), Oct. 2010, Peer-reviewed

  
• Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway.

  Takahiro Horie; Koh Ono; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Shin Watanabe; Yasuhide Kuwabara; Yasuhiro Nakashima; Rieko Takanabe-Mori; Eiichiro Nishi; Koji Hasegawa; Toru Kita; Takeshi Kimura

  Cardiovascular research, 01 Sep. 2010, Peer-reviewed

  
• 健常成人における可溶性血管内皮増殖因子受容体2の血清レベルはインスリン抵抗性に規定される

  和田啓道; 佐藤哲子; 北岡修二; 尾野亘; 森本達也; 川村晃久; 中野為夫; 藤田正俊; 北徹; 島津章; 長谷川浩二

  肥満研究, 01 Sep. 2010

  
• Lectin-like oxidized low-density lipoprotein receptor-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice.

  Rieko Takanabe-Mori; Koh Ono; Naoya Sowa; Hiromichi Wada; Tomohide Takaya; Takahiro Horie; Noriko Satoh-Asahara; Akira Shimatsu; Masatoshi Fujita; Tatsuya Sawamura; Koji Hasegawa

  Biochemical and biophysical research communications, 30 Jul. 2010, Peer-reviewed

  
• 梅毒抗原陽性を呈し,冠動脈3枝入口部狭窄を来した1症例

  中尾哲史; 早野護; 静田聡; 塩井哲雄; 尾野亘; 木村剛, 北徹

  日本老年医学会雑誌, 25 Jul. 2010

  
• 結核性心外膜炎が原因と思われる熱発と心不全症状を主訴とし,たこつぼ型心筋症と敗血症を合併し死亡した症例

  児玉暖; 近藤祥司; 川瀬裕一; 加藤義紘; 塩井哲雄; 尾野亘; 濱川慶之; 武地一; 荒井秀典; 若月芳雄

  日本老年医学会雑誌, 25 Jul. 2010

  
• 高齢心不全患者に対するチェア・エクササイズの安全性と効果

  吉田路子; 小笹寧子; 梅田陽子; 鮑炳元; 北川綾子; 武田真寿美; 塩井哲雄; 尾野亘; 木村剛

  心臓リハビリテーション, 15 Jun. 2010

  
• MicroRNAと心疾患

  尾野亘; 木村剛

  Bio Clin, 10 Jun. 2010

  
• Neural cell adhesion molecule is a cardioprotective factor up-regulated by metabolic stress.

  Kazuya Nagao; Koh Ono; Yoshitaka Iwanaga; Yodo Tamaki; Yoji Kojima; Takahiro Horie; Hitoo Nishi; Minako Kinoshita; Yasuhide Kuwabara; Koji Hasegawa; Toru Kita; Takeshi Kimura

  Journal of molecular and cellular cardiology, Jun. 2010, Peer-reviewed

  
• 心房細動の起源として上大静脈のtriggered activityの関与が推測された1症例

  中尾哲史; 静田聡; 早野護; 土井孝浩; 八幡光彦; 西山慶; 牧山武; 赤尾昌治; 塩井哲雄; 尾野亘; 北徹, 木村剛

  J Arrhythmia, 25 Apr. 2010

  
• 水溶性もしくは脂溶性スタチンとアンジオテンシン受容体拮抗薬の併用が生活習慣病患者の耐糖能に及ぼす影響

  和田啓道; 尾野亘; 佐藤哲子; 川村晃久; 森本達也; 上北和実; 東堂龍平; 山田和範; 赤尾昌治; 小坂田元太; 島津章; 長谷川浩二

  糖尿病, 25 Apr. 2010

  
• A case with sudden onset of position-dependent hypoxemia caused by reopening of foramen ovale.

  Tomohisa Tada; Masatoshi Fujita; Tomoyuki Goto; Toshihiro Tamura; Koh Ono; Toru Kita; Ken-Ichi Takahashi; Hiroaki Osada; Ryuzo Sakata; Takeshi Kimura

  Journal of cardiology cases, Apr. 2010, Peer-reviewed

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• MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via Arl2 in neonatal rat cardiac myocytes.

  Hitoo Nishi; Koh Ono; Yoshitaka Iwanaga; Takahiro Horie; Kazuya Nagao; Genzou Takemura; Minako Kinoshita; Yasuhide Kuwabara; Rieko Takanabe Mori; Koji Hasegawa; Toru Kita; Takeshi Kimura

  The Journal of biological chemistry, 12 Feb. 2010, Peer-reviewed

  
• Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing.

  Koh Ono; Xiaofei Wang; Sung Ouk Kim; Lucas C Armstrong; Paul Bornstein; Jiahuai Han

  Protein & cell, Feb. 2010, Peer-reviewed

  
• Soluble VEGF receptor-2 is increased in sera of subjects with metabolic syndrome in association with insulin resistance.

  Hiromichi Wada; Noriko Satoh; Shuji Kitaoka; Koh Ono; Tatsuya Morimoto; Teruhisa Kawamura; Tameo Nakano; Masatoshi Fujita; Toru Kita; Akira Shimatsu; Koji Hasegawa

  Atherosclerosis, Feb. 2010, Peer-reviewed

  
• Transmitral E/A ratio decreases in association with abdominal fat accumulation in patients with impaired glucose tolerance or mild diabetes without left ventricular hypertrophy

  Hiromichi Wada; Daisuke Shinjo; Sachika Kameda; Koh Ono; Noriko Satoh; Tatsuya Morimoto; Genta Osakada; Tameo Nakano; Masatoshi Fujita; Akira Shimatsu; Koji Hasegawa

  HEART AND VESSELS, Jan. 2010, Peer-reviewed

  
• Transmitral E/A ratio decreases in association with abdominal fat accumulation in patients with impaired glucose tolerance or mild diabetes without left ventricular hypertrophy.

  Hiromichi Wada; Daisuke Shinjo; Sachika Kameda; Koh Ono; Noriko Satoh; Tatsuya Morimoto; Genta Osakada; Tameo Nakano; Masatoshi Fujita; Akira Shimatsu; Koji Hasegawa

  Heart and vessels, Jan. 2010, Peer-reviewed

  
• 高ホモシステイン血症で下大静脈に血栓が生じ,肺塞栓となった一例

  八幡光彦; 加藤義紘; 仁木俊一郎; 東谷暢也; 中尾哲史; 塩見紘樹; 早野護; 多田朋弥; 田崎淳一; 陣内俊和; 土井孝浩; 田村俊寛; 小笹寧子; 静田聡; 尾野亘; 塩井哲雄; 堀内久徳; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• 肝移植ドナー検診で見つかった家族性Brugada症候群の兄弟例

  渋谷倫太郎; 早野護; 八幡光彦; 牧山武; 土井孝浩; 静田聡; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• ステロイドパルスが奏功したと考えられる心筋炎の一例

  仁木俊一郎; 塩見紘樹; 早野護; 牧山武; 土井孝浩; 小笹寧子; 田村俊寛; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• 慢性心房細動例に対しカテーテルアブレーションとbepridilにより洞調律維持が可能であった一例

  南野恵里; 早野護; 八幡光彦; 中尾哲史; 土井孝浩; 静田聡; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• 右冠動脈瘤を合併したベーチェット病の症例

  守上裕子; 陣内俊和; 多田朋弥; 田崎淳一; 小笹寧子; 土井孝浩; 田村俊寛; 静田聡; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• 発作性上室性頻拍症を来たし心不全を来した修正大血管転位症に対しアブレーション,CRT治療を行った例

  八幡光彦; 塩見紘樹; 仁木俊一郎; 東谷暢也; 早野護; 加藤義紘; 多田朋弥; 田崎淳一; 土井孝浩; 小笹寧子; 静田聡; 尾野亘; 塩井哲雄; 牧山武; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• たこつぼ型心筋症に心室中隔穿孔を合併し,保存的加療により救命し得た症例

  長峯彰子; 中尾哲史; 多田朋弥; 田村俊寛; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• PCI後にPPISを来した症例

  守上裕子; 塩見紘樹; 東谷暢也; 田崎淳一; 徳重明央; 今井逸雄; 牧山武; 小笹寧子; 土井孝浩; 静田聡; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• 心室性不整脈のコントロールに難渋した急性冠症候群の1例

  吉川慶; 陣内俊和; 仁木俊一郎; 多田朋弥; 田崎淳一; 小笹寧子; 土井孝浩; 田村俊寛; 静田聡; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• 人工股関節手術中に発症した脂肪塞栓症に対しPCPSで救命し得た一例

  仁木俊一郎; 中尾哲史; 早野護; 加藤義紘; 多田朋弥; 田崎淳一; 田村俊寛; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• 閉塞性動脈硬化症を合併し,PCI後に心外膜炎を発症した狭心症の一例

  東谷暢也; 田崎淳一; 小笹寧子; 田村俊寛; 尾野亘; 塩井哲雄; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• 若年発症のHCMに対してICD埋め込みを施行した例

  八幡光彦; 塩見紘樹; 仁木俊一郎; 東谷暢也; 中尾哲史; 早野護; 加藤義紘; 多田朋弥; 田崎淳一; 陣内俊和; 土井孝浩; 牧山武; 西山慶; 田村俊寛; 小笹寧子; 静田聡; 尾野亘; 塩井哲雄; 堀内久徳; 木村剛

  日本循環器学会近畿地方会(Web), 2010

  
• たこつぼ型心筋症に心室中隔穿孔を合併し,保存的加療にて救命し得た症例

  中尾哲史; 多田朋弥; 田村俊寛; 塩井哲雄; 尾野亘; 木村剛

  日本心エコー図学会学術集会抄録集, 2010

  
• Stanford B型大動脈解離に伴うMalperfusionにより腎血管性高血圧をきたし経皮的腎動脈形成術が奏効した1例

  田崎淳一; 田村俊寛; 当麻正直; 塩井哲雄; 尾野亘; 北徹, 木村剛

  Ther Res, 20 Dec. 2009

  
• The search for Nkx2-5-regulated genes using purified embryonic stem cell-derived cardiomyocytes with Nkx2-5 gene targeting.

  Yasuhiro Nakashima; Koh Ono; Yoshinori Yoshida; Yoji Kojima; Toru Kita; Makoto Tanaka; Takeshi Kimura

  Biochemical and biophysical research communications, 18 Dec. 2009, Peer-reviewed

  
• 術前に左前下行枝の造影遅延を含む2枝高度狭窄を認め2期的冠動脈血行再建を施行した脳腫瘍の1例

  塩見紘樹; 田村俊寛; 東谷暢也; 多田朋弥; 尾野亘; 木村剛

  日本冠疾患学会雑誌, 25 Nov. 2009

  
• FFR計測が有効であった,シロリムス溶出性ステント留置後のステント内再狭窄の2症例

  加藤義紘; 田村俊寛; 当麻正直; 尾野亘; 木村剛

  日本冠疾患学会雑誌, 25 Nov. 2009

  
• PCI時の側枝閉塞に起因する左室自由壁破裂の一症例

  中尾哲史; 木村剛; 田村俊寛; 仁木俊一郎; 東谷暢也; 八幡光彦; 加藤義紘; 早野護; 塩見紘樹; 田崎淳一; 多田朋也; 陣内俊和; 塩井哲雄; 尾野亘

  日本冠疾患学会雑誌, 25 Nov. 2009

  
• ステントグラフト留置後5年を経過して食道と大動脈瘤の交通を認めた胸部大動脈瘤の一例

  加藤義紘; 田崎淳一; 田村俊寛; 尾野亘; 木村剛; 井上寛治

  日本冠疾患学会雑誌, 25 Nov. 2009

  
• MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes.

  Takahiro Horie; Koh Ono; Hitoo Nishi; Yoshitaka Iwanaga; Kazuya Nagao; Minako Kinoshita; Yasuhide Kuwabara; Rieko Takanabe; Koji Hasegawa; Toru Kita; Takeshi Kimura

  Biochemical and biophysical research communications, 13 Nov. 2009, Peer-reviewed

  
• Inhibition of Histone Deacetylation Markedly Induces Myocardial Differentiation of Induced Pluripotent Stem Cells in Mice

  Kaichi Shinji; Hasegawa Koji; Takaya Tomohide; Morimoto Tatsuya; Kawamura Teruhisa; Ono Koh; Yokoo Noritaka; Mima Takahiro; Baba Shiro; Doi Hiraku; Yamanaka Shinya; Nakahata Tatsutoshi; Heike Toshio

  CIRCULATION, 03 Nov. 2009, Peer-reviewed

  
• 高血圧治療薬としてのシルニジピンの心臓自律神経活性への好影響

  猪飼亜希子; 竹島里紗; 小倉千佳; 山邉裕子; 尾野亘; 藤田正俊

  日本高血圧学会総会プログラム・抄録集, 01 Oct. 2009

  
• Progranulin expression in advanced human atherosclerotic plaque.

  Yoji Kojima; Koh Ono; Katsumi Inoue; Yasushi Takagi; Ken-ichiro Kikuta; Masaki Nishimura; Yoshinori Yoshida; Yasuhiro Nakashima; Hironobu Matsumae; Yutaka Furukawa; Nobuhiro Mikuni; Masakiyo Nobuyoshi; Takeshi Kimura; Toru Kita; Makoto Tanaka

  Atherosclerosis, Sep. 2009, Peer-reviewed

  
• 左室肥大のない耐糖能異常・軽度糖尿病患者において拡張障害の指標,僧帽弁E/A比は内臓脂肪蓄積に相関して低下している

  和田啓道; 尾野亘; 佐藤哲子; 森本達也; 小坂田元太; 中野為夫; 藤田正俊; 島津章; 長谷川浩二

  日本心臓病学会誌, 20 Aug. 2009

  
• MicroRNA-1 and MicroRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells.

  Tomohide Takaya; Koh Ono; Teruhisa Kawamura; Rieko Takanabe; Shinji Kaichi; Tatsuya Morimoto; Hiromichi Wada; Toru Kita; Akira Shimatsu; Koji Hasegawa

  Circulation journal : official journal of the Japanese Circulation Society, Aug. 2009, Peer-reviewed

  
• Impact of CYP2C19 polymorphisms on the antiplatelet effect of clopidogrel in an actual clinical setting in Japan.

  Toshikazu Jinnai; Hisanori Horiuchi; Takeru Makiyama; Junichi Tazaki; Tomohisa Tada; Masaharu Akao; Koh Ono; Kozo Hoshino; Yumiko Naruse; Kanako Takahashi; Haruyo Watanabe; Toru Kita; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, Aug. 2009, Peer-reviewed

  
• Mulberry leaf ameliorates the expression profile of adipocytokines by inhibiting oxidative stress in white adipose tissue in db/db mice.

  Masayuki Sugimoto; Hidenori Arai; Yukinori Tamura; Toshinori Murayama; Parinda Khaengkhan; Takuya Nishio; Koh Ono; Hiroyuki Ariyasu; Takashi Akamizu; Yukihiko Ueda; Toru Kita; Shigeharu Harada; Kaeko Kamei; Masayuki Yokode

  Atherosclerosis, Jun. 2009, Peer-reviewed

  
• メタボリックシンドロームと血管障害 メタボリックシンドロームと冠動脈イベントのリスク

  尾野亘; 木村剛

  分子心血管病, 01 Jun. 2009

  
• Let‐7,microRNA‐98は心筋細胞においてGLUT4の発現を低下させインスリン抵抗性を惹起する

  曽和尚也; 尾野亘; 堀江貴裕; 西仁勇; 長央和也; 木下美菜子; 森利依子; 阿部由希子; 北徹; 島津章; 長谷川浩二

  糖尿病, 25 Apr. 2009

  
• 左室肥大のない耐糖能異常・軽度糖尿病患者において拡張障害の指標,僧帽弁E/Aは内臓脂肪蓄積に相関して低下している

  和田啓道; 尾野亘; 佐藤哲子; 森本達也; 小坂田源太; 中野為夫; 藤田正俊; 島津章; 長谷川浩二

  糖尿病, 25 Apr. 2009

  
• 梅毒抗体陽性反応を示し,左右冠動脈入口部狭窄を来した1症例

  中尾哲史; 早野護; 静田聡; 塩井哲雄; 尾野亘; 木村剛, 北徹

  Circ J, 20 Apr. 2009

  
• 夫婦でたこつぼ型心筋症を生じた2例

  高橋宏輔; 寺田行範; 早野護; 当麻正直; 塩井哲雄; 尾野亘; 木村剛, 北徹

  Circ J, 20 Apr. 2009

  
• 全身性エリテマトーデスおよび心房中隔欠損症を合併し,深部静脈血栓症から肺塞栓および奇異性脳塞栓を起こした一例

  田崎淳一; 田村俊寛; 当麻正直; 塩井哲雄; 尾野亘; 木村剛, 北徹

  Circ J, 20 Apr. 2009

  
• PCI施行後に気腫性胆嚢炎をきたした1例

  多田朋弥; 青木一成; 静田聡; 塩井哲雄; 尾野亘; 木村剛, 北徹

  Circ J, Apr. 2009

  
• 結核性心膜炎に伴う心のう水貯留から心タンポナーデに至った1例

  川瀬裕一; 加藤義紘; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• aVRのST上昇が部位診断に有用であった急性心筋梗塞の一例

  夜久大晃; 加藤義紘; 田村俊寛; 中尾哲史; 早野護; 田崎淳一; 多田朋弥; 陣内俊和; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• ステントグラフト留置後5年を経過して食道と大動脈瘤の交通を認めた胸部大動脈瘤の一例

  松井宏行; 加藤義紘; 田崎淳一; 田村俊寛; 中尾哲史; 早野護; 塩見紘樹; 尾野亘; 塩井哲雄; 木村剛; 井上寛治

  日本循環器学会近畿地方会(Web), 2009

  
• 右肺動脈欠損症に合併した冠動脈気管支動脈瘻による冠盗血症候群に対しコイル塞栓術を施行した一例

  出口文子; 多田朋弥; 中尾哲史; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• 洞不全症候群を合併した心房細動に対してカテーテルアブレーションを行った一例

  早野護; 静田聡; 中尾哲史; 根津知行; 山口孝之; 塚本学; 土井孝浩; 西山慶; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• 難治性右鎖骨下動脈狭窄に対して繰り返し薬剤溶出性ステントを留置した大動脈炎症候群の一例

  南野恵里; 多田朋弥; 田村俊寛; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• 無症状で発見された心臓原発リンパ腫の一例

  仁木俊一郎; 中尾哲史; 田村俊寛; 尾野亘; 木村剛; 西澤正俊; 山下浩平; 辻崇

  日本循環器学会近畿地方会(Web), 2009

  
• カテーテルアブレーションにより著明に心機能改善を認めた拡張型心筋症合併慢性心房細動の一例

  早野護; 静田聡; 八幡光彦; 中尾哲史; 根津知行; 山口孝之; 塚本学; 土井孝浩; 西山慶; 牧山武; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• 孤立性上腸間膜動脈解離の2症例

  中尾哲史; 当麻正直; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• 急性大動脈解離に伴う腸管虚血に対してPTAが奏効しステントグラフト内挿術にて救命に成功した1例

  田崎淳一; 当麻正直; 高宜弘; 田村俊寛; 塩井哲雄; 尾野亘; 北徹, 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• 右側臥位にて著明な低酸素血症を呈した一例

  後藤知之; 多田朋弥; 藤田正俊; 田村俊寛; 尾野亘; 塩井哲雄; 北徹, 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• 心室中隔欠損を合併し心不全症状を呈した右室二腔症の1例

  中尾哲史; 田村俊寛; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• ステントグラフト内挿術後の大動脈瘤周囲に炎症を生じステロイドが奏功した2例

  東谷暢也; 田崎淳一; 当麻正直; 尾野亘; 丸井晃; 井上寛治; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• 2カ月以上の再発と遷延を認めた左室流出路狭窄を伴うたこつぼ型心筋症の1例

  水田弘人; 加藤義紘; 田村俊寛; 塩井哲雄; 尾野亘; 木村剛, 北徹

  日本循環器学会近畿地方会(Web), 2009

  
• カルバマゼピン内服後徐脈を来たし,血液透析濾過で洞調律に復帰した一症例

  小林洋平; 加藤義紘; 田村俊寛; 塩井哲雄; 尾野亘; 木村剛; 北徹; 渡部仁美; 家原典之; 深津敦司

  日本循環器学会近畿地方会(Web), 2009

  
• ボーリング中に心肺停止となった急性心筋梗塞に対しbystanderによる心肺蘇生と低体温療法で社会復帰した1例

  西村友美; 加藤義紘; 田村俊寛; 川瀬裕一; 中尾哲史; 高宜弘; 早野護; 田崎淳一; 多田朋弥; 陣内俊和; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• 肺動脈血栓塞栓症に類似した肺動脈血管肉腫

  川瀬裕一; 仁尾恵里那; 塩井哲雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2009

  
• Inhibition of CCR2 ameliorates insulin resistance and hepatic steatosis in db/db mice.

  Yukinori Tamura; Masayuki Sugimoto; Toshinori Murayama; Yukihiko Ueda; Hiroshi Kanamori; Koh Ono; Hiroyuki Ariyasu; Takashi Akamizu; Toru Kita; Masayuki Yokode; Hidenori Arai

  Arteriosclerosis, thrombosis, and vascular biology, Dec. 2008, Peer-reviewed

  
• 鎖骨下動脈狭窄に対して留置したステント内の繰り返す再狭窄に対して薬剤溶出性ステントを使用した大動脈炎症候群の1例

  多田朋弥; 田村俊寛; 田崎淳一; 当麻正直; 尾野亘; 赤尾昌治; 古川裕; 北徹, 木村剛

  Jpn J Cardiovasc Catheter Ther, 01 Dec. 2008

  
• 心エコーにて少量の心嚢水を認めた急性心筋梗塞に対してPCIを施行したoozing型左室自由壁破裂の1例

  早野護; 田村俊寛; 多田朋弥; 田崎淳一; 当麻正直; 尾野亘; 赤尾昌治; 北徹; 木村剛; 長田裕明; 仁科健

  Jpn J Cardiovasc Catheter Ther, 01 Dec. 2008

  
• Sirolimus Eluting Stent留置後早期ステント血栓症を発症した急性冠症候群の1例

  田崎淳一; 田村俊寛; 多田朋弥; 星野康三; 当麻正直; 尾野亘; 赤尾昌治; 古川裕; 北徹, 木村剛

  Jpn J Cardiovasc Catheter Ther, 01 Dec. 2008

  
• Up-regulated expression of microRNA-143 in association with obesity in adipose tissue of mice fed high-fat diet.

  Rieko Takanabe; Koh Ono; Yukiko Abe; Tomohide Takaya; Takahiro Horie; Hiromichi Wada; Toru Kita; Noriko Satoh; Akira Shimatsu; Koji Hasegawa

  Biochemical and biophysical research communications, 28 Nov. 2008, Peer-reviewed

  
• 劇症型心筋炎に急性肺障害を合併し,PCPS・ECMOを使用することで救命に成功した症例

  田崎淳一; 田村俊寛; 当麻正直; 尾野亘; 北徹; 赤尾昌治; 木村剛

  Circ J, 20 Oct. 2008

  
• 急性心筋梗塞後にoozing型左室自由壁破裂をきたした一例

  早野護; 田村俊寛; 尾野亘; 北徹; 赤尾昌治; 木村剛; 長田裕明; 仁科健

  Circ J, 20 Oct. 2008

  
• 産褥期のマイレン酸メチルエルゴメトリン内服との関連を否定できない冠攣縮性狭心症の一例

  仁木俊一郎; 齋藤成達; 早野護; 尾野亘; 北徹; 赤尾昌治; 木村剛

  Circ J, 20 Oct. 2008

  
• 血管内治療によりmalperfusionの解除に成功したStanford B型急性大動脈解離の2症例

  高宜弘; 当麻正直; 早野護; 田崎淳一; 齋藤成達; 尾野亘; 北徹; 赤尾昌治; 木村剛

  Circ J, 20 Oct. 2008

  
• 冠動脈疾患を合併し,左室肥大・びまん性左室機能低下を呈したミトコンドリア脳筋症の一例

  田崎淳一; 田村俊寛; 尾野亘; 北徹; 赤尾昌治; 木村剛

  Circ J, 20 Oct. 2008

  
• von Recklinghausen病に動脈破裂を合併し,血管内治療による止血に成功し救命し得た一例

  加藤義紘; 当麻正直; 齋藤成達; 尾野亘; 北徹; 赤尾昌治; 木村剛

  Circ J, 20 Oct. 2008

  
• カテーテルアブレーションにより心房機能が著明に改善した慢性心房細動の一例

  早野護; 静田聡; 花澤康司; 西山慶; 土井孝浩; 尾野亘; 北徹; 赤尾昌治; 木村剛

  Circ J, 20 Oct. 2008

  
• Statins activate GATA-6 and induce differentiated vascular smooth muscle cells.

  Hiromichi Wada; Mitsuru Abe; Koh Ono; Tatsuya Morimoto; Teruhisa Kawamura; Tomohide Takaya; Noriko Satoh; Masatoshi Fujita; Toru Kita; Akira Shimatsu; Koji Hasegawa

  Biochemical and biophysical research communications, 03 Oct. 2008, Peer-reviewed

  
• Morphological and biochemical characterization of basal and starvation-induced autophagy in isolated adult rat cardiomyocytes.

  Rumi Maruyama; Kazuko Goto; Genzou Takemura; Koh Ono; Kazuya Nagao; Takahiro Horie; Akiko Tsujimoto; Hiromitsu Kanamori; Shusaku Miyata; Hiroaki Ushikoshi; Kenshi Nagashima; Shinya Minatoguchi; Takako Fujiwara; Hisayoshi Fujiwara

  American journal of physiology. Heart and circulatory physiology, Oct. 2008, Peer-reviewed

  
• マウス脂肪組織におけるmicroRNA‐143の発現は肥満と共に増加する

  高鍋利依子; 尾野亘; 高谷智英; 堀江貴裕; 和田啓道; 北徹; 島津章; 長谷川浩二

  日本内分泌学会雑誌, 20 Sep. 2008

  
• micro RNAをターゲットとした肥満に伴う心血管系疾患治療法の開発

  尾野亘; 堀江貴裕; 西仁勇; 長央和也; 木下美菜子; 北徹

  Ther Res, 20 Aug. 2008

  
• 桑葉は酸化ストレスの抑制により脂肪組織における炎症とインスリン抵抗性を改善する

  杉本正志; 杉本正志; 荒井秀典; 田村行識; 村山敏典; 尾野亘; 上田之彦; 北徹; 亀井加恵子; 横出正之

  日本動脈硬化学会総会・学術集会プログラム・抄録集, 27 Jun. 2008

  
• TG-interacting factor is required for the differentiation of preadipocytes.

  Takahiro Horie; Koh Ono; Minako Kinoshita; Hitoo Nishi; Kazuya Nagao; Teruhisa Kawamura; Yukiko Abe; Hiromichi Wada; Akira Shimatsu; Toru Kita; Koji Hasegawa

  Journal of lipid research, Jun. 2008, Peer-reviewed

  
• Small dense LDL-cholesterol relative to LDL-cholesterol is a strong independent determinant of hypoadiponectinemia in metabolic syndrome.

  Noriko Satoh; Hiromichi Wada; Koh Ono; Hajime Yamakage; Kazunori Yamada; Tameo Nakano; Masakazu Hattori; Akira Shimatsu; Hideshi Kuzuya; Koji Hasegawa

  Circulation journal : official journal of the Japanese Circulation Society, Jun. 2008, Peer-reviewed

  
• CCN1 knockdown suppresses neointimal hyperplasia in a rat artery balloon injury model.

  Hironobu Matsumae; Yoshinori Yoshida; Koh Ono; Kiyonori Togi; Katsumi Inoue; Yutaka Furukawa; Yasuhiro Nakashima; Yoji Kojima; Masakiyo Nobuyoshi; Toru Kita; Makoto Tanaka

  Arteriosclerosis, thrombosis, and vascular biology, Jun. 2008, Peer-reviewed

  
• Oxidative stress induces GLUT4 translocation by activation of PI3-K/Akt and dual AMPK kinase in cardiac myocytes.

  Takahiro Horie; Koh Ono; Kazuya Nagao; Hitoo Nishi; Minako Kinoshita; Teruhisa Kawamura; Hiromichi Wada; Akira Shimatsu; Toru Kita; Koji Hasegawa

  Journal of cellular physiology, Jun. 2008, Peer-reviewed

  
• メタボリックシンドロームの心血管合併症における可溶性血管内皮増殖因子受容体2の意義

  和田啓道; 佐藤哲子; 尾野亘; 新城大輔; 森本達也; 中野為夫; 島津章; 藤田正俊; 長谷川浩二

  糖尿病, 25 Apr. 2008

  
• 肥満男性の血清可溶性VEGFレセプター2は減量成功により有意に低下する

  和田啓道; 新城大輔; 森本達也; 長谷川浩二; 佐藤哲子; 尾野亘; 中野爲夫; 島津章; 藤田正俊

  Circ J, 20 Apr. 2008

  
• Identification of p300-targeted acetylated residues in GATA4 during hypertrophic responses in cardiac myocytes.

  Tomohide Takaya; Teruhisa Kawamura; Tatsuya Morimoto; Koh Ono; Toru Kita; Akira Shimatsu; Koji Hasegawa

  The Journal of biological chemistry, 11 Apr. 2008, Peer-reviewed

  
• Pleiotropic effects of sarpogrelate in cardiovascular diseases

  M. Fujita; T. Morimoto; K. Ono; F. Terasaki

  Therapeutic Research, 2008, Peer-reviewed

  
• Cyclin-dependent kinase-9, as a novel component of p300/GATA4 complex, is involved in the differentiation of mouse ES cells into cardiac myocytes

  Kaichi Shinji; Takaya Tomohide; Morimoto Tatsuya; Sunagawa Yoichi; Kawamura Teruhisa; Ono Koh; Kite Toru; Hidaka Kyoko; Morisaki Takayuld; Baba Shiro; Heike Toshio; Nakahata Tatsutoshi; Hasegawa Koji

  CIRCULATION, 16 Oct. 2007, Peer-reviewed

  
• MCP‐1のシグナル遮断は肥満モデルマウスにおける内臓脂肪蓄積とインスリン抵抗性を改善する

  荒井秀典; 田村行織; 村山敏典; 尾野亘; 北徹; 横出正之

  肥満研究, 20 Sep. 2007

  
• メタボリックシンドロームから虚血性心疾患発症・進展におけるsVEGFR‐2の意義

  和田啓道; 佐藤哲子; 尾野亘; 新城大輔; 森本達也; 中野為夫; 島津章; 藤田正俊; 長谷川浩二

  肥満研究, 20 Sep. 2007

  
• 21世紀フォーラム心血管病とリスクファクター 5th 脂肪細胞由来セロトニンを標的としたメタボリックシンドローム治療法の開発

  尾野亘; 堀江貴裕; 木下美菜子; 長央和也; 西仁勇; 森利依子; 長谷川浩二; 北徹

  血圧, 01 Sep. 2007

  
• インスリンによるTG‐interacting factorの活性化は前駆脂肪細胞の分化に必要である

  堀江貴裕; 尾野亘; 阿部由希子; 川村晃久; 島津明; 長谷川浩二; 北徹

  糖尿病, 30 Jun. 2007

  
• 血管新生因子可溶性受容体の血中濃度はメタボリック症候群において有意に上昇している

  和田啓道; 尾野亘; 亀田幸花; 阿部由希子; 川村晃久; 森本達也; 北徹; 島津章; 中野為夫; 葛谷英嗣; 佐藤哲子; 長谷川浩二

  糖尿病, 30 Jun. 2007

  
• CCR2阻害剤プロパゲルマニウムは肥満モデルマウスにおけるインスリン抵抗性を改善する

  田村行識; 荒井秀典; 杉本正志; 村山敏典; 上田之彦; 尾野亘; 北徹; 横出正之

  日本動脈硬化学会総会・学術集会プログラム・抄録集, 27 Jun. 2007

  
• Trichostatin A induces myocardial differentiation of monkey ES cells.

  Mohsen Hosseinkhani; Koji Hasegawa; Koh Ono; Teruhisa Kawamura; Tomohide Takaya; Tatsuya Morimoto; Hiromichi Wada; Akira Shimatsu; Susana Gonzalez Prat; Hirofumi Suemori; Norio Nakatsuji; Toru Kita

  Biochemical and biophysical research communications, 04 May 2007, Peer-reviewed

  
• Leptin induces elongation of cardiac myocytes and causes eccentric left ventricular dilatation with compensation.

  Yukiko Abe; Koh Ono; Teruhisa Kawamura; Hiromichi Wada; Toru Kita; Akira Shimatsu; Koji Hasegawa

  American journal of physiology. Heart and circulatory physiology, May 2007, Peer-reviewed

  
• Serum adiponectin level as an independent predictor of mortality in patients with congestive heart failure.

  Toshihiro Tamura; Yutaka Furukawa; Ryoji Taniguchi; Yukihito Sato; Koh Ono; Hisanori Horiuchi; Yoshihisa Nakagawa; Toru Kita; Takeshi Kimura

  Circulation journal : official journal of the Japanese Circulation Society, May 2007, Peer-reviewed

  
• CCN1 protects cardiac myocytes from oxidative stress via beta1 integrin-Akt pathway.

  Yoshinori Yoshida; Kiyonori Togi; Hironobu Matsumae; Yasuhiro Nakashima; Yoji Kojima; Hiromi Yamamoto; Koh Ono; Tomoyuki Nakamura; Toru Kita; Makoto Tanaka

  Biochemical and biophysical research communications, 13 Apr. 2007, Peer-reviewed

  
• 耐糖能障害の病態解明―GLUT4トランスロケーション機構の解明―

  尾野亘; 堀江貴裕; 北徹

  代謝異常治療研究基金研究業績集, 2007

  
• 遺伝子トラップ法によるES細胞から心筋細胞分化に必須の遺伝子の同定と分化誘導療法への応用

  尾野亘

  上原記念生命科学財団研究報告集, 14 Nov. 2006

  
• Three catheter-based strategies for cardiac delivery of therapeutic gelatin microspheres

  K. Hoshino; T. Kimura; A. M. De Grand; R. Yoneyama; Y. Kawase; S. Houser; H. Q. Ly; T. Kushibiki; Y. Furukawa; K. Ono; Y. Tabata; J. V. Frangioni; T. Kita; R. J. Hajjar; M. Hayase

  GENE THERAPY, Sep. 2006, Peer-reviewed

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• 脂肪由来セロトニンによる脂肪細胞分化とメタボリックシンドローム病態制御機構の解明

  尾野亘

  Ther Res, 20 Jul. 2006

  
• 内因性VEGF阻害物質である可溶性VEGF受容体2(sFlk‐1)の血清濃度はメタボリック症候群において有意に上昇している.

  和田啓道; 尾野亘; 亀田幸花; 阿部由希子; 川村晃久; 森本達也; 北徹; 島津章; 中野為夫; 葛谷英嗣; 佐藤哲子; 長谷川浩二

  糖尿病, 25 Apr. 2006

  
• インスリンによるTG‐interacting Factor(TGIF)の活性化は前駆脂肪細胞の分化に必要である

  堀江貴裕; 尾野亘; 阿部由希子; 川村晃久; 島津章; 北徹; 長谷川浩二

  糖尿病, 25 Apr. 2006

  
• 耐糖能障害・軽度糖尿病患者においても左室拡張障害が存在する

  亀田幸花; 和田啓道; 尾野亘; 川村晃久; 森本達也; 北徹; 島津章; 中野為夫; 小坂田元太; 葛谷英嗣; 新城大輔; 長谷川浩二

  糖尿病, 25 Apr. 2006

  
• Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling after myocardial infarction in adult mice in vivo.

  Shoichi Miyamoto; Teruhisa Kawamura; Tatsuya Morimoto; Koh Ono; Hiromichi Wada; Yosuke Kawase; Akira Matsumori; Ryosuke Nishio; Toru Kita; Koji Hasegawa

  Circulation, 07 Feb. 2006, Peer-reviewed

  
• Angiotensin-converting enzyme genotype is not associated with exercise capacity or the training effect of cardiac rehabilitation in patients after acute myocardial infarction.

  Yoshitaka Iwanaga; Isao Nishi; Koh Ono; Shuichi Takagi; Yoshiaki Tsutsumi; Masanori Ozaki; Teruo Noguchi; Hiroshi Takaki; Naoharu Iwai; Hiroshi Nonogi; Yoichi Goto

  Circulation journal : official journal of the Japanese Circulation Society, Nov. 2005, Peer-reviewed

  
• エンケファリンは脂肪組織に発現し,脂肪細胞分化に必要である

  阿部由希子; 尾野亘; 佐藤哲子; 和田啓道; 川村晃久; 亀田幸花; 島津章; 長谷川浩二; 森本達也; 宮本昌一; 北徹

  日本内分泌学会雑誌, 20 Sep. 2005

  
• レプチンは心筋細胞長径増大作用を有し,心筋梗塞後の代償性肥大を誘導する

  阿部由希子; 尾野亘; 川村晃久; 宮本昌一; 森本達也; 和田啓道; 島津章; 北徹; 長谷川浩二

  肥満研究, 20 Sep. 2005

  
• レトロウイルスによる遺伝子トラップ法を用いた脂肪細胞分化に必須な遺伝子の同定

  尾野亘; 阿部由希子; 川村晃久; 和田啓道; 島津章; 北徹; 長谷川浩二

  肥満研究, 20 Sep. 2005

  
• レプチンは心筋細胞長径増大作用を有し,心筋梗塞後の代償性肥大を誘導する

  阿部由希子; 尾野亘; 川村晃久; 宮本昌一; 森本達也; 和田啓道; 島津章; 北徹; 長谷川浩二

  日本内分泌学会雑誌, 20 Sep. 2005

  
• ヒストン脱アセチル化酵素の阻害は心筋細胞への分化をこう進する。

  川村晃久; 尾野亘; 森本達也; 長谷川浩二; 日高京子; 森崎隆幸; 平家俊男; 中畑龍俊; 末盛博文; 中辻憲夫; 北徹

  日本臨床分子医学会記録, 31 May 2005

  
• Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes

  Teruhisa Kawamura; Koh Ono; Tatsuya Morimoto; Hiromichi Wada; Maretoshi Hirai; Kyoko Hidaka; Takayuki Morisaki; Toshio Heike; Tatsutoshi Nakahata; Toru Kita; Koji Hasegawa

  Journal of Biological Chemistry, 20 May 2005, Peer-reviewed

  
• Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes.

  Teruhisa Kawamura; Koh Ono; Tatsuya Morimoto; Hiromichi Wada; Maretoshi Hirai; Kyoko Hidaka; Takayuki Morisaki; Toshio Heike; Tatsutoshi Nakahata; Toru Kita; Koji Hasegawa

  The Journal of biological chemistry, 20 May 2005, Peer-reviewed

  
• シンバスタチンはII型糖尿病のラットモデルにおいて左室拡張能障害を改善する

  宮本昌一; 尾野亘; 阿部由希子; 森本達也; 川村晃久; 葛谷英嗣; 島津章; 長谷川浩二

  糖尿病, 25 Apr. 2005

  
• レトロウイルスによる遺伝子トラップ法を用いた脂肪細胞分化に必須な遺伝子の同定

  尾野亘; 阿部由希子; 川村晃久; 宮本昌一; 森本達也; 島津章; 長谷川浩二

  糖尿病, 25 Apr. 2005

  
• 国立病院機構ネットワーク臨床共同研究「糖尿病・耐糖能障害の心,腎,血管合併症に対する最適な薬物療法の確立」の立ち上げ

  川村晃久; 尾野亘; 森本達也; 阿部由希子; 宮本昌一; 葛谷英嗣; 島津章; 長谷川浩二

  糖尿病, 25 Apr. 2005

  
• レプチンによる初代ラット培養心筋細胞の肥大効果

  阿部由希子; 尾野亘; 川村晃久; 森本達也; 宮本昌一; 島津章; 長谷川浩二

  糖尿病, 25 Apr. 2005

  
• Identification of a novel insertion mutation in GATA3 with HDR syndrome.

  Yukari Mino; Takashi Kuwahara; Toshifumi Mannami; Keisuke Shioji; Koh Ono; Naoharu Iwai

  Clinical and experimental nephrology, Mar. 2005, Peer-reviewed

  
• カニクイザルES細胞の心筋細胞への分化およびPTCAバルーンカテーテルによる心筋梗塞モデルへの投与

  江原夏彦; HOSSEINKANI M; 尾野亘; 川村晃久; 古川裕; 北徹; 末盛博文; 中辻憲夫; 長谷川浩二

  再生医療, 10 Feb. 2005

  
• 天然物成分クルクミンは心筋細胞核内アセチル化抑制を介して心筋細胞肥大を抑制する

  森本達也; 尾野亘; 川村晃久; 北徹; 長谷川浩二

  日本循環薬理学会口演要旨集, 2005

  
• Preformed angiotensin II is present in human mast cells.

  Masatake Hara; Koh Ono; Hiromi Wada; Shigetake Sasayama; Akira Matsumori

  Cardiovascular drugs and therapy, Nov. 2004, Peer-reviewed

  
• 細胞移植と再生医療―血管新生から心筋再生へ―ES細胞を用いた心筋再生療法

  江原夏彦; HOSSEINKHAIN M; 北徹; 川村晃久; 尾野亘; 長谷川浩二

  循環器科, 28 Oct. 2004

  
• レプチンによる初代ラット培養心筋細胞の肥大効果

  阿部由希子; 尾野亘; 川村晃久; 島津章; 長谷川浩二; 森本達也; 北徹

  日本内分泌学会雑誌, 20 Sep. 2004

  
• FOG-2 competes with GATA-4 for transcriptional coactivator p300 and represses hypertrophic responses in cardiac myocytes.

  Maretoshi Hirai; Koh Ono; Tatsuya Morimoto; Teruhisa Kawamura; Hiromichi Wada; Toru Kita; Koji Hasegawa

  The Journal of biological chemistry, 03 Sep. 2004, Peer-reviewed

  
• p53Arg72Pro polymorphism of tumour suppressor protein is associated with luminal narrowing after coronary stent placement

  S Kojima; N Iwai; N Tago; K Ono; K Ohmi; G Tsujimoto; S Takagi; S Miyazaki; H Nonogi; Y Goto

  HEART, Sep. 2004, Peer-reviewed

  
• Activators of PPARgamma antagonize protection of cardiac myocytes by endothelin-1.

  Natsuhiko Ehara; Koji Hasegawa; Koh Ono; Teruhisa Kawamura; Eri Iwai-Kanai; Tatsuya Morimoto; Masaharu Akao; Souichi Adachi; Toru Kita

  Biochemical and biophysical research communications, 20 Aug. 2004, Peer-reviewed

  
• Contribution of caveolin-1 alpha and Akt to TNF-alpha-induced cell death.

  Koh Ono; Yoshitaka Iwanaga; Madoka Hirayama; Teruhisa Kawamura; Naoya Sowa; Koji Hasegawa

  American journal of physiology. Lung cellular and molecular physiology, Jul. 2004, Peer-reviewed

  
• Endothelin-1-dependent nuclear factor of activated T lymphocyte signaling associates with transcriptional coactivator p300 in the activation of the B cell leukemia-2 promoter in cardiac myocytes.

  Teruhisa Kawamura; Koh Ono; Tatsuya Morimoto; Masaharu Akao; Eri Iwai-Kanai; Hiromichi Wada; Naoya Sowa; Toru Kita; Koji Hasegawa

  Circulation research, 11 Jun. 2004, Peer-reviewed

  
• A promoter variant of the heme oxygenase-1 gene may reduce the incidence of ischemic heart disease in Japanese.

  Koh Ono; Yoichi Goto; Shuichi Takagi; Shunroku Baba; Naomi Tago; Hiroshi Nonogi; Naoharu Iwai

  Atherosclerosis, Apr. 2004, Peer-reviewed

  
• Expression of p300 protects cardiac myocytes from apoptosis in vivo.

  Teruhisa Kawamura; Koji Hasegawa; Tatsuya Morimoto; Eri Iwai-Kanai; Shoichi Miyamoto; Yosuke Kawase; Koh Ono; Hiromichi Wada; Masaharu Akao; Toru Kita

  Biochemical and biophysical research communications, 12 Mar. 2004, Peer-reviewed

  
• Suppression of cytokines and nitric oxide production, and protection against lethal endotoxemia and viral myocarditis by a new NF-kappaB inhibitor.

  Akira Matsumori; Youichi Nunokawa; Akira Yamaki; Kanjo Yamamoto; Myung-Woo Hwang; Tadashi Miyamoto; Masatake Hara; Ryosuke Nishio; Katsura Kitaura-Inenaga; Koh Ono

  European journal of heart failure, 01 Mar. 2004, Peer-reviewed

  
• The possible role of peroxisome proliferator-activated receptor gamma in heart failure.

  Natsuhiko Ehara; Koh Ono; Tatsuya Morimoto; Teruhisa Kawamura; Mitsuru Abe; Koji Hasegawa

  Experimental and clinical cardiology, 2004, Peer-reviewed

  
• Association analysis between polymorphisms of the lymphotoxin-alpha gene and myocardial infarction in a Japanese population

  Y Iwanaga; K Ono; S Takagi; M Terashima; Y Tsutsumi; T Mannami; N Yasui; Y Goto; H Nonogi; N Iwai

  ATHEROSCLEROSIS, Jan. 2004, Peer-reviewed

  
• Heterozygous disruption of CMA1 does not affect blood pressure.

  Koh Ono; Yoshihiro Kokubo; Toshifumi Mannami; Nozomu Inamoto; Keisuke Shioji; Naoharu Iwai

  Journal of hypertension, Jan. 2004, Peer-reviewed

  
• Association analysis between polymorphisms of the lymphotoxin-alpha gene and myocardial infarction in a Japanese population.

  Yoshitaka Iwanaga; Koh Ono; Shuichi Takagi; Masahiro Terashima; Yoshiaki Tsutsumi; Toshifumi Mannami; Naomi Yasui; Yoichi Goto; Hiroshi Nonogi; Naoharu Iwai

  Atherosclerosis, Jan. 2004, Peer-reviewed

  
• Gene expression of cardiac mast cell chymase and tryptase in a murine model of heart failure caused by viral myocarditis.

  Katsura Kitaura-Inenaga; Masatake Hara; Kazuhiro Higuchi; Kanjo Yamamoto; Akira Yamaki; Koh Ono; Atsushi Nakano; Makoto Kinoshita; Shigetake Sasayama; Akira Matsumori

  Circulation journal : official journal of the Japanese Circulation Society, Oct. 2003, Peer-reviewed

  
• Epidemiological evidence of an association between SLC6A2 gene polymorphism and hypertension.

  Koh Ono; Yoshitaka Iwanaga; Toshifumi Mannami; Yoshihiro Kokubo; Hitonobu Tomoike; Kazuo Komamura; Keisuke Shioji; Naomi Yasui; Naomi Tago; Naoharu Iwai

  Hypertension research : official journal of the Japanese Society of Hypertension, Sep. 2003, Peer-reviewed

  
• 心筋梗塞関連遺伝子多型の検討

  岩永善高; 尾野亘; 後藤葉一; 万波俊文; 野々木宏; 岩井直温

  日本動脈硬化学会総会プログラム・抄録集, 01 Sep. 2003

  
• Cタイプ・ナトリウム利尿ホルモン遺伝子遺伝的多型と高血圧の関連解析

  尾野亘; 万波俊文; 友池仁暢; 菅真一; 岩井直温

  Ther Res, 20 Aug. 2003

  
• Association of a promoter variant of the haeme oxygenase-1 gene with hypertension in women

  K Ono; T Mannami; N Iwai

  JOURNAL OF HYPERTENSION, Aug. 2003, Peer-reviewed

  
• Association of a promoter variant of the haeme oxygenase-1 gene with hypertension in women.

  Koh Ono; Toshifumi Mannami; Naoharu Iwai

  Journal of hypertension, Aug. 2003, Peer-reviewed

  
• Orphan nuclear receptor Nur77 is involved in caspase-independent macrophage cell death.

  Sung Ouk Kim; Koh Ono; Peter S Tobias; Jiahuai Han

  The Journal of experimental medicine, 02 Jun. 2003, Peer-reviewed

  
• An acyl-CoA synthetase gene family in chromosome 16p12 may contribute to multiple risk factors.

  Naoharu Iwai; Toshifumi Mannami; Hitonobu Tomoike; Koh Ono; Yoshitaka Iwanaga

  Hypertension (Dallas, Tex. : 1979), May 2003, Peer-reviewed

  
• 心臓・血管疾患の本態解明に関する研究 遺伝子破壊法によるネクローシスシグナル伝達遺伝子のクローニング

  尾野亘

  持田記念財団年報, 01 Apr. 2003

  
• Lack of association between angiotensin II type 1 receptor gene polymorphism and hypertension in Japanese.

  Koh Ono; Toshifumi Mannami; Shunroku Baba; Naomi Yasui; Toshio Ogihara; Naoharu Iwai

  Hypertension research : official journal of the Japanese Society of Hypertension, Feb. 2003, Peer-reviewed

  
• Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death.

  Koh Ono; Sung O Kim; Jiahuai Han

  Molecular and cellular biology, Jan. 2003, Peer-reviewed

  
• A GPVI polymorphism is a risk factor for myocardial infarction in Japanese

  S Takagi; N Iwai; S Baba; T Mannami; K Ono; C Tanaka; T Miyata; S Miyazaki; H Nonogi; Y Goto

  ATHEROSCLEROSIS, Dec. 2002, Peer-reviewed

  
• Aldehyde dehydrogenase 2 gene is a risk factor for myocardial infarction in Japanese men.

  Shuichi Takagi; Naoharu Iwai; Ryoko Yamauchi; Sunao Kojima; Shinji Yasuno; Takeshi Baba; Masahiro Terashima; Yoshiaki Tsutsumi; Shoji Suzuki; Isao Morii; Sotaro Hanai; Koh Ono; Shunroku Baba; Hitonobu Tomoike; Atsushi Kawamura; Shunichi Miyazaki; Hiroshi Nonogi; Yoichi Goto

  Hypertension research : official journal of the Japanese Society of Hypertension, Sep. 2002, Peer-reviewed

  
• A single-nucleotide polymorphism in C-type natriuretic peptide gene may be associated with hypertension.

  Koh Ono; Toshifumi Mannami; Shunroku Baba; Hitonobu Tomoike; Sin-ichi Suga; Naoharu Iwai

  Hypertension research : official journal of the Japanese Society of Hypertension, Sep. 2002, Peer-reviewed

  
• Amiodarone inhibits interleukin 6 production and attenuates myocardial injury induced by viral myocarditis in mice.

  Haruyasu Ito; Koh Ono; Ryousuke Nishio; Shigetake Sasayama; Akira Matsumori

  Cytokine, 21 Feb. 2002, Peer-reviewed

  
• Evidence for a role of mast cells in the evolution to congestive heart failure.

  Masatake Hara; Koh Ono; Myung-Woo Hwang; Atsushi Iwasaki; Masaharu Okada; Kazuki Nakatani; Shigetake Sasayama; Akira Matsumori

  The Journal of experimental medicine, 04 Feb. 2002, Peer-reviewed

  
• Circulating hepatocyte growth factor as a diagnostic marker of thrombus formation in patients with cerebral infarction.

  Akira Matsumori; Hajime Takano; Jun-ei Obata; Satoshi Takeda; Naohiko Tsuyuguchi; Koh Ono; Masaharu Okada; Tadashi Miyamoto; Tomokazu Ohnishi; Yasushi Daikuhara; Shigetake Sasayama

  Circulation journal : official journal of the Japanese Circulation Society, Feb. 2002, Peer-reviewed

  
• Endothelin antagonism with bosentan: current status and future perspectives.

  Koh Ono; Akira Matsumori

  Cardiovascular drug reviews, 2002, Peer-reviewed

  
• Resistance to tumor necrosis factor-induced cell death mediated by PMCA4 deficiency

  K Ono; XF Wang; JH Han

  MOLECULAR AND CELLULAR BIOLOGY, Dec. 2001, Peer-reviewed

  
• Apoptosis by pan-caspase inhibitors in lipopolysaccharide-activated macrophages

  SO Kim; K Ono; JH Han

  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Nov. 2001, Peer-reviewed

  
• Neutralization of interleukin-1 beta in the acute phase of myocardial infarction promotes the progression of left ventricular remodeling

  MW Hwang; A Matsumori; Y Furukawa; K Ono; M Okada; A Iwasaki; M Hara; T Miyamoto; M Touma; S Sasayama

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Nov. 2001, Peer-reviewed

  
• Gene suppression by tristetraprolin and release by the p38 pathway

  W Zhu; MA Brauchle; F Di Padova; H Gram; L New; K Ono; JS Downey; JH Han

  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Aug. 2001, Peer-reviewed

  
• Metaxin is required for tumor necrosis factor-induced cell death

  XF Wang; K Ono; SO Kim; Kravchenko, V; SC Lin; JH Han

  EMBO REPORTS, Jul. 2001, Peer-reviewed

  
• Role of p38 mitogen-activated protein kinase in neointimal hyperplasia after vascular injury

  N Ohashi; A Matsumori; Y Furukawa; K Ono; M Okada; A Iwasaki; T Miyamoto; A Nakano; S Sasayama

  ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, Dec. 2000, Peer-reviewed

  
• Circulating hepatocyte growth factor as a marker of thrombus formation in unstable angina pectoris

  A Matsumori; S Miyazaki; H Takano; K Ono; M Okada; T Miyamoto; H Nonogi; S Daikoku; K Mitsudo; Y Matsunaga; T Ohnishi; Y Daikuhara; S Sasayama

  JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, Oct. 2000, Peer-reviewed

  
• Hypertrophic cardiomyopathy as a manifestation of cardiac sarcoidosis

  A Matsumori; M Hara; S Nagai; T Izumi; N Ohashi; K Ono; S Sasayama

  JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, Sep. 2000, Peer-reviewed

  
• Roles and relationship of macrophages and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in the ischemic and reperfused rat heart

  T Kakio; A Matsumori; K Ono; H Ito; K Matsushima; S Sasayama

  LABORATORY INVESTIGATION, Jul. 2000, Peer-reviewed

  
• Amlodipine inhibits the production of cytokines induced by ouabain

  A Matsumori; K Ono; R Nishio; Y Nose; S Sasayama

  CYTOKINE, Mar. 2000, Peer-reviewed

  
• 肥満細胞を介する新しい心不全発症機序 代償性心肥大から非代償性心肥大への移行における肥満細胞の関与

  原正剛; 松森昭; 尾野亘; 篠山重威

  Jpn Circ J, 01 Mar. 2000

  
• ラット頚動脈バルーン傷害モデルにおける新生内膜形成に及ぼすp38 MAPキナーゼ阻害剤の効果

  大橋直弘; 松森昭; 古川裕; 尾野亘; 岩崎篤志; 岡田正治; 宮本忠司; 中野敦; 篠山重威

  Jpn Circ J, 01 Mar. 2000

  
• The p38 signal transduction pathway - Activation and function

  K Ono; JH Han

  CELLULAR SIGNALLING, Jan. 2000, Peer-reviewed

  
• Mast cells cause apoptosis of cardiomyocytes and proliferation of other intramyocardial cells in vitro

  A Matsumori; M Hara; K Ono; MW Hwang; T Miyamoto; S Sasayama

  CARDIOVASCULAR PHARMACOTHERAPY, 2000, Peer-reviewed

  
• High doses of digitalis increase the myocardial production of proinflammatory cytokines and worsen myocardial injury in viral myocarditis - A possible mechanism of digitalis toxicity

  A Matsumori; H Igata; K Ono; A Iwasaki; T Miyamoto; R Nishio; S Sasayama

  JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, Dec. 1999, Peer-reviewed

  
• Contribution of endothelin-1 to myocardial injury in a murine model of myocarditis - Acute effects of bosentan, an endothelin receptor antagonist

  K Ono; A Matsumori; T Shioi; Y Furukawa; S Sasayama

  CIRCULATION, Oct. 1999, Peer-reviewed

  
• Cytokine gene expression during the development of graft coronary artery disease in mice

  Y Furukawa; A Matsumori; MW Hwang; T Hirozane; K Ono; T Shioi; S Sasayama

  JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, Oct. 1999, Peer-reviewed

  
• Mast cells cause apoptosis of cardiomyocytes and proliferation of other intramyocardial cells in vitro

  M Hara; A Matsumori; K Ono; H Kido; MW Hwang; T Miyamoto; A Iwasaki; M Okada; K Nakatani; S Sasayama

  CIRCULATION, Sep. 1999, Peer-reviewed

  
• FTY720, a new immunosuppressant, promotes long-term graft survival and inhibits the progression of graft coronary artery disease in a murine model of cardiac transplantation

  MW Hwang; A Matsumori; Y Furukawa; K Ono; M Okada; A Iwasaki; M Hara; S Sasayama

  CIRCULATION, Sep. 1999, Peer-reviewed

  
• Apical hypertrophic cardiomyopathy and hepatitis C virus infection

  A Matsumori; N Ohashi; R Nishio; T Kakio; M Hara; Y Furukawa; K Ono; T Shioi; K Hasegawa; S Sasayama

  JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, Jun. 1999, Peer-reviewed

  
• Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric oxide synthase in a murine model of viral myocarditis

  A Iwasaki; A Matsumori; T Yamada; T Shioi; WZ Wang; K Ono; R Nishio; M Okada; S Sasayama

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Apr. 1999, Peer-reviewed

  
• Anti-monocyte chemoattractant protein-1 monocyte chemotactic and activating factor antibody inhibits neointimal hyperplasia in injured rat carotid arteries

  Y Furukawa; A Matsumori; N Ohashi; T Shioi; K Ono; A Harada; K Matsushima; S Sasayama

  CIRCULATION RESEARCH, Feb. 1999, Peer-reviewed

  
• Prevention of myocardial reperfusion injury in rats by an antibody against monocyte chemotactic and activating factor monocyte chemoattractant protein-1

  K Ono; A Matsumori; Y Furukawa; H Igata; T Shioi; K Matsushima; S Sasayama

  LABORATORY INVESTIGATION, Feb. 1999, Peer-reviewed

  
• Hepatocyte growth factor is a major mediator in heparin-induced angiogenesis

  M Okada; A Matsumori; K Ono; T Miyamoto; M Takahashi; S Sasayama

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Feb. 1999, Peer-reviewed

  
• Role of cytokines and NO in the pathogenesis of congestive heart failure.

  尾野亘; 松森昭; 篠山重威

  循環器科, Feb. 1999

  
• Current treatment for heart failure

  K. Ono; A. Matsumori; S. Sasayma

  Respiration and Circulation, 1999, Peer-reviewed

  
• Erratum: Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric oxide synthase in a murine model of viral myocarditis (Journal of the American College of Cardiology (1999) 33 (1400-14007))

  A. Iwasaki; A. Matsumori; Y. Takehiko; T. Shioi; W. Wang; K. Ono; R. Nishio; M. Okada; S. Sasayama

  Journal of the American College of Cardiology, 1999, Peer-reviewed

  
• Cytokines and Cardiovascular Diseases. Chemokines in ischemic heart disease.

  尾野亘; 松森昭

  循環器科, Dec. 1998

  
• Immediate increase in circulating hepatocyte growth factor/scatter factor by heparin

  A Matsumori; K Ono; M Okada; T Miyamoto; Y Sato; S Sasayama

  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Oct. 1998, Peer-reviewed

  
• Denopamine, a beta 1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: Suppression of tumor necrosis factor-alpha production in the heart

  R Nishio; A Matsumori; T Shioi; WZ Wang; T Yamada; K Ono; S Sasayama

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Sep. 1998, Peer-reviewed

  
• Cytokine gene expression after myocardial infarction in rat hearts - Possible implication in left ventricular remodeling

  K Ono; A Matsumori; T Shioi; Y Furukawa; S Sasayama

  CIRCULATION, Jul. 1998, Peer-reviewed

  
• Cyclic stretch upregulates production of interleukin-8 and monocyte chemotactic and activating factor monocyte chemoattractant protein-1 in human endothelial cells

  M Okada; A Matsumori; K Ono; Y Furukawa; T Shioi; A Iwasaki; K Matsushima; S Sasayama

  ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, Jun. 1998, Peer-reviewed

  
• Circulating hepatocyte growth factor as an early marker of arterial thrombus formation

  A Matsumori; K Ono; Y Furukawa; M Okada; S Sasayama

  JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, Apr. 1998, Peer-reviewed

  
• Basic Research and Clinical Relevance of Chemokines. Functions of Chemokines in Cardiovascular Disease.

  尾野亘; 松森昭

  最新医学, Apr. 1998

  
• Enhanced expression of hepatocyte growth factor/c-Met by myocardial ischemia and reperfusion in a rat model

  K. Ono; A. Matsumori; T. Shioi; Y. Furukawa; S. Sasayama

  Journal of Cardiology, 1998, Peer-reviewed

  
• Increased expression of interleukin-1 beta and monocyte chemotactic and activating factor monocyte chemoattractant protein-1 in the hypertrophied and failing heart with pressure overload

  T Shioi; A Matsumori; Y Kihara; M Inoko; K Ono; Y Iwanaga; T Yamada; A Iwasaki; K Matsushima; S Sasayama

  CIRCULATION RESEARCH, Nov. 1997, Peer-reviewed

  
• Apoptosis in an experimental model of viral myocarditis in mice.

  山田武彦; 松森昭; 塩井哲雄; 大橋直弘; 尾野亘; 篠山重威; WANG W Z

  心筋の構造と代謝, Nov. 1997

  
• Role of interleukin 12 in viral myocarditis.

  塩井哲雄; 松森昭; 西尾亮介; 尾野亘; 垣尾匡史; 篠山重威

  日本免疫学会総会・学術集会記録, Oct. 1997

  
• Amiodarone inhibits production of tumor necrosis factor-α by human mononuclear cells: A possible mechanism for its effect in heart failure

  Akira Matsumori; Koh Ono; Ryosuke Nishio; Yoshisuke Nose; Shigetake Sasayama

  Circulation, 02 Sep. 1997, Peer-reviewed

  
• Modulation of cytokine production and protection against lethal endotoxemia by the cardiac glycoside ouabain

  A Matsumori; K Ono; R Nishio; H Igata; T Shioi; S Matsui; Y Furukawa; A Iwasaki; Y Nose; S Sasayama

  CIRCULATION, Sep. 1997, Peer-reviewed

  
• Protective role of interleukin-12 in viral myocarditis

  T Shioi; A Matsumori; R Nishio; K Ono; T Kakio; S Sasayama

  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Sep. 1997, Peer-reviewed

  
• Cardiovascular reconstruction. Functional disorder brought about by cardiovascular reconstruction.Cytokine, growth factor, and heart reconstruction.

  尾野亘; 松森昭; 篠山重威

  Heart View, Sep. 1997

  
• Enhanced expression of hepatocyte growth factor/c-Met by myocardial ischemia and reperfusion in a rat model

  K. Ono; A. Matsumori; T. Shioi; Y. Furakawa; S. Sasayama

  Circulation, 03 Jun. 1997, Peer-reviewed

  
• Treatment strategy of the medical diseases based on evidence. Circulatory organ. Cardiomyopathy.

  尾野亘; 松森昭

  内科, Jun. 1997

  
• Varicose vein and venous thrombosis; Myocardial disease.

  尾野亘; 松森昭

  綜合臨床, May 1997

  
• Plasma levels of the monocyte chemotactic and activating factor monocyte chemoattractant protein-1 are elevated in patients with acute myocardial infarction

  A Matsumori; Y Furukawa; T Hashimoto; A Yoshida; K Ono; T Shioi; M Okada; A Iwasaki; R Nishio; K Matsushima; S Sasayama

  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Jan. 1997, Peer-reviewed

  
• Cardiac hypertrophy, dilatation and to cardiac insufficiency. From the cardiac hypertrophy to the cardiac insufficiency.

  尾野亘; 松森昭

  Heart View, Jan. 1997

  
• Differential modulation of cytokine production by drugs: Implications for therapy in heart failure

  A Matsumori; K Ono; Y Sato; T Shioi; Y Nose; S Sasayama

  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Dec. 1996, Peer-reviewed

  
• New birth intimal proliferation control by anti-MCAF/MCP-1 antibody. Examination with rat carotid artery injury model.

  古川裕; 松森昭; 塩井哲雄; 尾野亘; 松島綱治; 篠山重威

  日本免疫学会総会・学術集会記録, Oct. 1996

  
• Involvement of cytokinein in heart ventricle remodeling with rat myocardial infarction model.

  尾野亘; 松森昭; 塩井哲雄; 古川裕; 井形英樹; 篠山重威

  日本免疫学会総会・学術集会記録, Oct. 1996

  
• Inotropic agents differentially inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages

  A Matsumori; Okada, I; T Shioi; Y Furukawa; T Nakamura; K Ono; A Iwasaki; S Sasayama

  LIFE SCIENCES, Aug. 1996, Peer-reviewed

  
• Cardiomyopathy. Natural progress of hypertrophic cardiomyopathy.

  佐藤幸人; 竹村元三; 尾野亘; 竹内雄三; 片岡一明; 伊藤晴康; 鷹津良樹

  診療と新薬, Jul. 1996

  
• Detection of hepatitis C virus RNA from the heart of patients with hypertrophic cardiomyopathy

  A Matsumori; Y Matoba; R Nishio; T Shioi; K Ono; S Sasayama

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, May 1996, Peer-reviewed

  
• Increased circulating hepatocyte growth factor in the early stage of acute myocardial infarction

  A Matsumori; Y Furukawa; T Hashimoto; K Ono; T Shioi; M Okada; A Iwasaki; R Nishio; S Sasayama

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 1996, Peer-reviewed

  
• Immunomodulation by an adenylate cyclase activator, NKH477, in vivo and in vitro

  Y Furukawa; A Matsumori; T Hirozane; S Matsui; Y Sato; K Ono; S Sasayama

  CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, Apr. 1996, Peer-reviewed

  
• Example of aortitis disease syndrome showing coronary ostium stenosis. (Hyogo Prefectural Amagasaki Hospital S) (Hyogo Prefectural Inst. for Oriental Medicine S).

  大畑順子; 尾野亘; 太田真弓; 和泉俊明; 竹村元三; 鷹津良樹; 山中一朗; 笹橋望; 安藤史隆

  兵庫県立尼崎病院年報, Mar. 1996

  
• Coronary diseases - from its morbid state to clinic.Morbid state of coronary diseases.Ventricular remodeling and its development to cardiac insufficiency.

  尾野亘; 松森昭; 篠山重威

  臨床医, Aug. 1995

  
• A case of acute fulminant myocarditis which combined Guillain-Barre syndrome.

  木下道広; 松本圭司; 市川桂二; 鷹津良樹; 尾野亘; 竹村元三; 藤原久義

  日本内科学会雑誌, Feb. 1995

  
• USEFULNESS OF ELECTRON-MICROSCOPY IN THE DIAGNOSIS OF CARDIAC SARCOIDOSIS

  G TAKEMURA; Y TAKATSU; K ONO; T IZUMI; H FUJIWARA

  HEART AND VESSELS, 1995, Peer-reviewed

  
• Transvenous Pacemaker Implantation of Sick Sinus Syndrome associated with Persistent Left Superior Vena Cava.

  笹橋望; 安藤史隆; 岡本文雄; 山中一郎; 大谷成裕; 曾我部浩; 花田智樹; 尾野亘; 松野修一

  呼吸と循環, Apr. 1994

  
• A case of aged ( 82-year-old ) Epstein's abnormality.

  尾野真弓; 尾野亘; 竹村元三; 鷹津良樹

  血管と心研究会誌, Feb. 1993

  
• A case of acute myocardial infarction combined with coronary ectasia without accompaning stenotic lesions.

  尾野亘; 尾野真弓; 鷹津良樹

  血管と心研究会誌, Sep. 1992

  
• Contribution of caveolin-1??and Akt to TNF-??induced cell death. Am J Physiol 2004; 287: 201-209.

  Ono K; Iwanaga Y; Hirayama M; Kawamura T; Sowa N; Hasegawa K

  Peer-reviewed

  

Misc.

• Post-discharge Use of Tolvaptan in Patients with Heart Failure as a Predictor of 2-year Rehospitalization: Explainable Artificial-Intelligence Based Study

  糀谷泰彦; 糀谷泰彦; 糀谷泰彦; 山本絵里香; 内野詠一郎; 田中宗和; 瀬尾拓哉; 仲山加奈子; 高野橋健太; 尾野亘; 奥野恭史; 奥野恭史

  日本循環器学会学術集会(Web), 2024

  
• 洞不全症候群に対してリードレスペースメーカ植込み後,VVI作動時にショックとなった1例

  西脇修司; 井上智之; 森永晃史; 米田史哉; 田中宗和; 糀谷泰彦; 静田聡; 尾野亘

  植込みデバイス関連冬季大会プログラム・抄録集(Web), 2024

  
• VF zoneでICD頻回作動する頻拍を心内電位解析からTypical AVNRTと推定できた1例

  井上智之; 西脇修司; 森永晃史; 米田史哉; 田中宗和; 相澤卓範; 糀谷泰彦; 静田聡; 尾野亘

  植込みデバイス関連冬季大会プログラム・抄録集(Web), 2024

  
• microRNA-33bの特異的抑制は炎症反応経路を介して腹部大動脈瘤形成を抑制する

  山崎智弘; 堀江貴裕; 小山智史; 中尾哲史; 馬場理; 曽和尚也; 小比賀聡; 小比賀聡; 笠原勇矢; 笠原勇矢; 小寺淳; 岡幸蔵; 藤田領; 佐々木隆史; 竹宮明広; 木村剛; 尾野亘

  日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), 2022

  
• microRNA-33bの特異的抑制による腹部大動脈瘤形成抑制効果の検討

  山崎智弘; 堀江貴裕; 小山智; 中尾哲史; 馬場理; 曽和尚也; 小比賀聡; 小比賀聡; 笠原勇矢; 小寺淳; 岡幸蔵; 藤田領; 佐々木隆史; 竹宮明広; 木村剛; 尾野亘

  日本動脈硬化学会総会・学術集会プログラム・抄録集(Web), 2021

  
• 持続性心房細動に対するアブレーション中に大量の右左シャントによる低酸素血症で救命困難となった不整脈原性右室心筋症の1例

  井上智之; 喜多村恭平; 羽賀博典; 森永晃史; 米田史哉; 西脇修司; 田中宗和; 糀谷泰彦; 牧山武; 尾野亘; 静田聡

  日本心臓病学会学術集会(Web), 2023

  
• 上大静脈をtriggerとし冠状静脈洞とマーシャル静脈の分岐部をsubstrateとするAFを心内心電図より明瞭に同定できた1例

  田中宗和; 静田聡; 井上智之; 森永晃史; 米田史哉; 西脇修司; 糀谷泰彦; 尾野亘

  日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023

  
• QDOT Micro電極とBi-polar電極の電位を比較することでOriginを推定し,大動脈左冠尖からの通電で同時に根治した2種類のLV summit PVCの1例

  西脇修司; 井上智之; 森永晃史; 米田史哉; 田中宗和; 糀谷泰彦; 静田聡; 尾野亘

  日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023

  
• 右房分界稜に著明なfractionated potentialsをみとめ,exit blockを伴う発火と頻拍中の拡張期電位をみとめた肺静脈隔離後の心房頻拍の1例

  井上智之; 静田聡; 森永晃史; 米田史哉; 西脇修司; 田中宗和; 糀谷泰彦; 尾野亘

  日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023

  
• QDOTのマイクロ電極に著明なdelayed potentialが記録された心尖部瘤を伴う肥大型心筋症の心室頻拍の1例

  米田史哉; 静田聡; 井上智之; 森永晃史; 田中宗和; 西脇修司; 糀谷泰彦; 尾野亘

  日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023

  
• QDOTカテーテルを用いたアブレーションのおけるContact Forceによる違いによる食道傷害の検討

  西脇修司; 静田聡; 井上智之; 森永晃史; 米田史哉; 田中宗和; 糀谷泰彦; 尾野亘

  日本不整脈心電学会カテーテルアブレーション関連大会(Web), 2023

  
• The analysis of CT and 3D-VRCT images in highly elderly patients with congestive heart failure/pulmonary edema

  何澤信礼; 井上良一; 尾野亘; 久米典昭; 南方謙二; 池田義; 坂田隆造

  臨床放射線, 2012

  
• CMA1機能欠損変異はトロンビン不活性化を介して心筋梗塞発生を増加させる(Loss-of-Function Mutation of CMA1 Increase the Incidence of Myocardial Infarction by Thrombin Inactivation)

  尾野 亘; 高木 修一; 宮崎 俊一; 野々木 宏; 後藤 葉一; 万波 俊文; 岩井 直温

  日本動脈硬化学会総会プログラム・抄録集, Sep. 2003

  
• アルデヒド脱水酵素2遺伝子は日本人男子における心筋梗塞危険因子の1つである(Aldehyde Dehydrogenase 2 Gene Is a Risk Factor for Myocardial Infarction in Japanese Men)

  尾野 亘; 高木 修一; 宮崎 俊一; 野々木 宏; 後藤 葉一; 万波 俊文; 友池 仁暢; 岩井 直温

  日本動脈硬化学会総会プログラム・抄録集, Sep. 2003

  
• Imidaprilとsimvastatinの併用は血清可溶性VEGF受容体2レベルを低下させる

  浦 修一; 和田 啓道; 浅原 哲子; 尾野 亘; 森本 達也; 島津 章; 長谷川 浩二

  肥満研究, Sep. 2012

  
• 高脂肪食負荷マウスの脂肪組織においてLOX-1はMCP-1と密接に関連して発現が誘導される

  高鍋 利依子; 尾野 亘; 阿部 由希子; 和田 啓道; 高谷 智英; 佐藤 哲子; 島津 章; 藤田 正俊; 沢村 達也; 長谷川 浩二

  日本臨床分子医学会学術総会プログラム・抄録集, Apr. 2009

  
• Different roles of monocyte chemoattractant protein-1 in smokers and nonsmokers

  S. Shimada; M. Komiyama; K. Ono; H. Wada; H. Yamakage; N. Asahara; M. Akao; T. Morimoto; Y. Takahashi; K. Hasegawa

  EUROPEAN HEART JOURNAL, Aug. 2016

  
• Neural cell adhesion molecule is a cardioprotective factor upregulated by metabolic stress

  K. Nagao; K. Ono; T. Horie; Y. Tamaki; Y. Iwanaga; T. Makita; T. Inada; M. Tanaka; T. Kita; T. Kimura

  EUROPEAN HEART JOURNAL, Aug. 2011

  
• OE-334 Overexpression of MicroRNA-1 in Mouse Embryonic Stem Cells Represses Myocardial Differentiation(Development and differentiation(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

  Takaya Tomohide; Kawamura Teruhisa; Ono Koh; Takanabe Rieko; Kaichi Shinji; Kita Toru; Wada Hiromichi; Morimoto Tatsuya; Shimatsu Akira; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2008

  
• OE-166 Upregulation of MicroRNA Targeting Retinoid X Receptor A Contributes to Development of Cardiac Hypertrophy(Molecular biology, myocardium (M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

  Nishi Hitoo; Ono Koh; Horie Takahiro; Kinoshita Minako; Nagao Kazuya; Iwanaga Yoshitaka; Hasegawa Koji; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2008

  
• PE-182 A Soluble VEGF Receptor-2 is a Possible Novel Biomaker of Cardiovascular Risk in the Metabolic Syndrome(Diabetes/Obesity/Metabolic syndrome(05)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

  Wada Hiromichi; Satoh Noriko; Ono Koh; Shinjo Daisuke; Morimoto Tatsuya; Nakano Tameo; Shimatsu Akira; Fujita Masatoshi; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2008

  
• OE-233 MicroRNA-133 Regulates the Expression of GLUT4 by Targeting KLF15 and is Involved in Metabolic Control in Cardiac Myocytes(Metabolism/Biochemistry/Energetics(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

  Horie Takahiro; Ono Koh; Kinoshita Minako; Nishi Hitoo; Nagao Kazuya; Mori Rieko; Iwanaga Yoshitaka; Hasegawa Koji; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2008

  
• PE-419 Enkephalin is Required for Adipocyte Differentiation and is Involved in Impaired Glucose Tolerance in Rat Model of Type II Diabetes(Diabetes/Obesity/Metabolic syndrome-06, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Ono Koh; Horie Takahiro; Takanabe Rieko; Kinoshita Minako; Nishi Hitoo; Nagao Kazuya; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• PE-409 Functional Cloning of the Genes which Regulates GLUT4 Trafficking in Cardiac Myocytes(Diabetes/Obesity/Metabolic syndrome-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Kinoshita Minako; Ono Koh; Horie Takahiro; Nagao Kazuya; Nishi Hitoo; Hasegawa Koji; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• PE-417 Activation of TG-interacting Factor by Insulin Regulates Adipocyte Differentiation(Diabetes/Obesity/Metabolic syndrome-06, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Horie Takahiro; Ono Koh; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• PE-531 A GATA-4 Mutant Lacking p300-Induced Acetylation Suppresses Myocardial Cell Hypertrophy(Molecular biology, myocardium-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Takaya Tomohide; Kawamura Teruhisa; Morimoto Tatsuya; Ono Koh; Kita Toru; Shimatsu Akira; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• OJ-201 Serum Levels of Soluble Flk-1, an Endogenous Inhibitor of VEGF, are Decreased by Weight Reduction Therapy in Male Obese Patients(Diabetes/Obesity/Metabolic syndrome-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Wada Hiromichi; Satoh Noriko; Ono Koh; Shinjo Daisuke; Morimoto Tatsuya; Kawamura Teruhisa; Nakano Tameo; Yamada Kazunori; Shimatsu Akira; Fujita Masatoshi; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• FRS-024 Up-Regulated Expression of MicroRNA-143 in the Adipose Tissue of High-Fat Diet-Induced Obese Mice(Diabetes/Obesity (basic), The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Takanabe Rieko; Ono Koh; Takaya Tomohide; Horie Takahiro; Kita Toru; Shimatsu Akira; Hasegawa Kouji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• PE-368 Soluble FIK-1, an Endogenous Inhibitor of Vascular Endothelial Growth Factor is Increased in Serum of Smoking Men(Smoking, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Wada Hiromichi; Funato Tadao; Shinjo Daisuke; Ono Koh; Satoh Noriko; Morimoto Tatsuya; Kawamura Teruhisa; Nakano Tameo; Shimatsu Akira; Fujita Masatoshi; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• OE-109 Trapping of Genes that Encode Secreted and Transmembrane Proteins in H9C2 cardiomyoblasts(Growth factor/Cytokine-1(H/M), The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Nagao Kazuya; Ono Koh; Horie Takahiro; Nishi Hitoo; Kinoshita Minako; Hasegawa Koji; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• OE-134 Regulated Expression of MicroRNAs During Differentiation of Mouse Embryonic Stem Cells into Cardiac Myocytes(Development and differentiation-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Takaya Tomohide; Kawamura Teruhisa; Ono Koh; Takanabe Rieko; Kaichi Shinji; Kita Toru; Wada Hiromichi; Morimoto Tatsuya; Shimatsu Akira; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• PE-171 Oxidative Stress Induces GLUT4 Translocation by Dual AMPK Kinase Activation in Cardiac Myocytes(Metabolism/Biochemistry/Energetics-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Horie Takahiro; Ono Koh; Wada Hiromichi; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• PE-172 miR-133 Controls GLUT4 Expression by Targeting KLF15 in Cardiomyocytes(Metabolism/Biochemistry/Energetics-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Horie Takahiro; Ono Koh; Nishi Hitoo; Nagao Kazuya; Kinosita Minako; Hasegawa Koji; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• OE-317 MicroRNA-206 Controls Expression of α-and β-Myosin Heavy Chain Genes in Cardiac Myocytes(Molecular biology, myocardium-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

  Nishi Hitoo; Ono Koh; Horie Takahiro; Kinoshita Minako; Nagao Kazuya; Hasegawa Koji; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2007

  
• 第2回心不全学会学術集会

  松森 昭; 尾野 亘

  循環制御 = CIRCULATION CONTROL, 18 Dec. 1998

  
• 0864 ラット心筋虚血再灌流モデルにおける肝細胞増殖因子(HGF)とその受容体(c-Met)の発現とその意義

  尾野 亘; 松森 昭; 塩井 哲雄; 古川 裕; 篠山 重威

  Japanese circulation journal, 05 Mar. 1997

  
• 0895 エンドセリン受容体拮抗薬TAK-044のウイルス性心筋炎マウスにおける生存率改善作用と心保護作用

  井形 英樹; 北吉 正人; 渡邊 敏文; 尾野 亘; 松森 昭

  Japanese circulation journal, 05 Mar. 1997

  
• P100 ヒト臍帯静脈内皮細胞(HUVEC)の伸展刺激によるサイトカイン産生に関する研究

  岡田 正治; 松森 昭; 塩井 哲雄; 古川 裕; 尾野 亘; 岩崎 篤志; 篠山 重威; 松島 綱治

  Japanese circulation journal, 05 Mar. 1997

  
• P351 ウイルス性心筋炎におけるエンドセリンの産生動態とエンドセリン受容体拮抗薬による治療効果の検討

  尾野 亘; 松森 昭; 井形 英樹; 篠山 重威

  Japanese circulation journal, 05 Mar. 1997

  
• P352 ウイルス性心筋炎におけるTh1及びTh2サイトカインの役割

  塩井 哲雄; 松森 昭; 尾野 亘; 西尾 亮介; 篠山 重威

  Japanese circulation journal, 05 Mar. 1997

  
• 1038 抗MCAF抗体投与によるラット頚動脈新生内膜過増殖の抑制

  古川 裕; 松森 昭; 塩井 哲雄; 尾野 亘; 篠山 重威; 松島 綱治

  Japanese circulation journal, 05 Mar. 1997

  
• 1046 ウイルス性心筋炎におけるインターロイキン12の役割

  塩井 哲雄; 松森 昭; 尾野 亘; 西尾 亮介; 垣尾 匡史; 篠山 重威

  Japanese circulation journal, 05 Mar. 1997

  
• MAPキナーゼ

  尾野 亘

  循環器専門医 : 日本循環器学会専門医誌, 20 Apr. 1998

  
• Genetics of Coronary Heart Diseases

  Ono Koh; Takagi Shuichi; Miyazaki Shunichi; Nonogi Hiroshi; Goto Yoichi; Iwai Naoharu

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2003

  
• SLC6A2 May Be One of the Genes Contributing to Hypertension in Japanese

  Iwanaga Yoshitaka; Ono Koh; Mannami Toshifumi; Iwai Naoharu

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2003

  
• 0119 心筋梗塞後左室リモデリングにおける抗IL1β治療の有効性の検討

  黄 明宇; 松森 昭; 尾野 亘; 古川 裕; 篠山 重威

  Japanese circulation journal, 01 Mar. 2000

  
• 0581 マウス心移植モデルを用いた新規免疫抑制剤FTY720の有効性の検討

  黄 明宇; 松森 昭; 古川 裕; 尾野 亘; 篠山 重威

  Japanese circulation journal, 28 Feb. 1998

  
• 0484 心筋梗塞後リモデリングにおける炎症サイトカインの関与

  尾野 亘; 松森 昭; 塩井 哲雄; 古川 裕; 篠山 重威

  Japanese circulation journal, 28 Feb. 1998

  
• 1099 ピモペンダンの心筋炎・心不全マウスにおける炎症性サイトカインおよびiNOS産生抑制効果

  岩崎 篤志; 松森 昭; 尾野 亘; 西尾 亮介; 篠山 重威

  Japanese circulation journal, 28 Feb. 1998

  
• IS056 Recombinant hepatocyte growth factor induces capillary endothelial regeneration in a rat model of myocardial ischemia and reperfusion

  Ono Koh; Matsumori Akira; Shioi Tetsuo; Furukawa Yutaka; Sasayama Shigetake

  Japanese circulation journal, 28 Feb. 1998

  
• P848 ヒト臍帯静脈内皮細胞(HUVEC)における機械的伸展刺激によるケモカイン産生誘導機序の検討

  岡田 正治; 松森 昭; 尾野 亘; 古川 裕; 岩崎 篤志; 篠山 重威; 松島 綱治

  Japanese circulation journal, 28 Feb. 1998

  
• 0922 致死的敗血症におけるAmiodaroneの効果

  尾野 亘; 松森 昭; 伊藤 晴康; 篠山 重威

  Japanese circulation journal, 28 Feb. 1998

  
• p300-mediated Inhibition of Doxorubicin-induced Myocardial Cell Apoptosis Involves Ubiquitin-dependent p53 Degradation by Mdm2(Apoptosis/Necrosis/Regeneration 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

  Morimoto Tatsuya; Ono Koh; Kawamura Teruhisa; Miyamoto Shoichi; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2005

  
• Differentiation of Monkey ES Cells into Cardiac Myocytes And Their Delivery into the Monkey Infracted Myocardium through PTCA Balloon Catheters(Apoptosis/Necrosis/Regeneration 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

  Hoseinkani Mohsen; Ono Koh; Kawamura Teruhisa; Ehara Natsuhiko; Morimoto Tatsuya; Furukawa Yutaka; Kita Toru; Suemori Hirofumi; Nakatsuji Norio; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2005

  
• Enkephalin is Expressed in Visceral Adipose Tissue And Required for Differentiation into Mature Adipocytes(Diabetes/Obesity 4 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

  Ono Koh; Abe Yukiko; Kawamura Teruhisa; Shimatsu Akira; Morimoto Tatsuya; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2005

  
• Chromatin Remodeling during Differentiation of ES Cells into Cardiac Myocytes(Cardiovascular Development, The 69th Annual Scientific Meeting of the Japanese Circulation Society)

  Hasegawa Koji; Ono Koh; Morimoto Tatsuya; Kawamura Teruhisa; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2005

  
• Epigallocatechin-3-gallate, a Major Polyphenolic Constituent of Green Tea, Induces Apoptosis in 3T3-L1 Preadipocytes After Induction of Differentiation(Diabetes/Obesity 3 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

  Abe Yukiko; Ono Koh; Kawamura Teruhisa; Morimoto Tatsuya; Kita Toru; Shimatsu Akira; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2005

  
• Continuous Low-doses of G-CSF Therapy Improve Left Ventricular Systolic Function in Cardiomyopathic Hamsters of End-staged Heart Failure(Heart Failure, Basic 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

  Kawamura Teruhisa; Miyamoto Shoichi; Ono Koh; Morimoto Tatsuya; Abe Yukiko; Kanoh Mayumi; Kuwaki Tomoaki; Nomura Hideaki; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2005

  
• Identification of Genes Required for Adipocyte Differentiation by Retrovirus Insertion-mediated Random Mutagenesis(Development and Differentiation 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

  Ono Koh; Abe Yukiko; Kawamura Teruhisa; Shimatsu Akira; Morimoto Tatsuya; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2005

  
• Leptin Activates JAK2/STAT3 Pathways And Induces Elongation in Cardiac Myocytes(Cardiac Hypertrophy 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

  Abe Yukiko; Ono Koh; Kawamura Teruhisa; Shimatsu Akira; Morimoto Tatsuya; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2005

  
• Chemical Inhibitors of Histone Acetyltransferase Represses Phenylephrine-induced Hypertrophic Responses in Cardiac Myocytes(Cardiac Hypertrophy 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

  Kawamura Teruhisa; Morimoto Tatsuya; Ono Koh; Abe Yukiko; Miyamoto Shoichi; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2005

  
• P427 選択的β1作動薬denopamineのウイルス性心筋炎による心不全モデルにおける効果の検討

  西尾 亮介; 松森 昭; 塩井 哲雄; 尾野 亘; 王 衛中; 篠山 重威

  Japanese circulation journal, 20 Feb. 1996

  
• 0466 肥満細胞はキマーゼを介して心筋細胞のアポトーシスを誘導し, 非心筋細胞を増殖させる

  原 正剛; 松森 昭; 尾野 亘; 篠山 重威; 木戸 博; 仲谷 和記

  Japanese circulation journal, 01 Mar. 1999

  
• P830 インスリン様増殖因子-1はウイルス増殖を促進し心筋炎を悪化する

  中野 敦; 松森 昭; 尾野 亘; 伊藤 晴康; 篠山 重威

  Japanese circulation journal, 01 Mar. 1999

  
• 0613 マウス心筋梗塞モデルを用いたIL-1b, 抗IL-1b抗体の急性期における効果の検討

  黄 明宇; 松森 昭; 古川 裕; 尾野 亘; 岩崎 篤志; 岡田 正治; 宮本 忠司; 大橋 直弘; 原 正剛; 篠山 重威

  Japanese circulation journal, 01 Mar. 1999

  
• P052 心筋炎・心不全マウスにおけるアミオダロンの炎症性サイトカイン産生抑制および生存率改善効果

  伊藤 晴康; 松森 昭; 尾野 亘; 西尾 亮介; 篠山 重威

  Japanese circulation journal, 01 Mar. 1999

  
• 0797 ウィルス性心筋炎モデルにおける肥満細胞の役割 : ヘルパーT細胞分化への関与の可能性

  宮本 忠司; 松森 昭; 塩井 哲雄; 尾野 亘; 岩崎 篤志; 西尾 亮介; 篠山 重威

  Japanese circulation journal, 01 Mar. 1999

  
• 1065 内因性抗酸化剤Adult T cell leukemia-derived factor(ADF)はNF-kBの活性化を抑制し再灌流障害を軽減する

  中野 敦; 松森 昭; 尾野 亘; 篠山 重威; 木村 比登史; 淀井 淳司

  Japanese circulation journal, 01 Mar. 1999

  
• PE-349 Leptin Induces Physiological and Compensated Growth of the Left Ventricles Following Myocardial Infarction in Vivo(Diabetes/Obesity/Metabolic syndrome-7 (H) PE59,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

  Abe Yukiko; Ono Koh; Kawamura Teruhisa; Miyamoto Shoichi; Wada Hiromichi; Horie Takahiro; Shimatsu Akira; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2006

  
• PE-245 Adipocyte-derived Serotonin Regulates Adipocyte Differentiation via an Autocrine/paracrine Mechanism(Diabetes/Obesity/Metabolic syndrome-8 (H) PE41,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

  Ono Koh; Horie Takahiro; Abe Yukiko; Kawamura Teruhisa; Shimatsu Akira; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2006

  
• OJ-048 A Soluble Flk-1, an Endogenous Inhibitor of Vascular Endothelial Growth Factor, is Increased in Serum of Patients with Metabolic Syndrome(Diabetes/Obesity/Metabolic syndrome-3 (H) OJ8,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

  Wada Hiromichi; Ono Koh; Kameda Sachica; Abe Yukiko; Kawamura Teruhisa; Morimoto Tatsuya; Kita Toru; Shimatsu Akira; Nakano Tameo; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2006

  
• PJ-736 A Natural p300 Specific Acetyltransferase Inhibitor, Crucumin, Represses Phenylephrine-induced Hypertrophic Responses in Cardiac Myocytes(Cardiac hypertrophy, basic/clinical-4 (M) PJ125,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

  Morimoto Tatsuya; Ono Koh; Kawamura Teruhisa; Miyamoto Shoichi; Wada Hiromichi; Kita Toru; Hasegawa Kouji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2006

  
• OE-196 Identification of Signaling Pathways that Mediate Myocardial GLUT4 Translocation using a Novel Lenti Viral-mediated GLUT4 Reporter Gene(Metabolism/Biochemistry/Energetics-1 (H) OE33,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

  Horie Takahiro; Ono Koh; Abe Yukiko; Kawamura Teruhisa; Shimatsu Akira; Hasegawa Koji; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2006

  
• 4 The Effects of Ubiquitin Ligase p300 on the Cardiac Myocytes Apoptosis(Signaling pathways that modulate differentiation and death in cardiovascular cells,Topic 6 (TP6) (M),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

  Morimoto Tatsuya; Ono Koh; Kawamura Teruhisa; Wada Hiromichi; Miyamoto Shoici; Kita Toru; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2006

  
• 36) 産褥期のマレイン酸メチルエルゴメトリン内服との関連を否定できない冠攣縮性狭心症の一例(第105回日本循環器学会近畿地方会)

  仁木 俊一郎; 齋藤 成達; 早野 護; 尾野 亘; 北 徹; 赤尾 昌治; 木村 剛

  Circulation journal : official journal of the Japanese Circulation Society, 20 Oct. 2008

  
• KCHF Study InvestigatorsSex differences in patients with acute decompensated heart failure in Japan: observation from the KCHF registry (vol 7, pg 2485, 2020)

  Erika Yamamoto; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Yoshihiro Himura; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mitsunori Kawato; Yuta Seko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura

  ESC HEART FAILURE, Feb. 2021

  
• Optimal Cut-Off Value for Fractional Flow Reserve Derived From Coronary Computed Tomography Angiography for Predicting Hemodynamically Significant Coronary Artery Disease

  Yukiko Matsumura-Nakano; Hiroki Shiomi; Tetsuma Kawaji; Masako Kataoka; Kanae Miyake-Kawai; Charles A. Taylor; Sohie Khem; Shojiro Tatsushima; Hirotoshi Watanabe; Junichi Tazaki; Masao Imai; Naritatsu Saito; Satoshi Shizuta; Koh Ono; Takeshi Morimoto; Takeshi Kimura

  CIRCULATION, Nov. 2017

  
• OE-392 Progranulin Expression in Advanced Human Atherosclerotic Plaque(OE66,Atherosclerosis (Clinical/Pathophysiology) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

  Kojima Yoji; Ono Koh; Inoue Katsumi; Yoshida Yoshinori; Nakashima Yasuhiro; Matsumae Hironobu; Furukawa Yutaka; Nobuyoshi Masakiyo; Kimura Takeshi; Kita Toru; Tanaka Makoto

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2009

  
• PE-263 Neural Cell Adehesion Molecule is Upregulated by Metabolic Stress and Enhances the Cardiomyocyte Survival(PE044,Molecular Biology (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

  Nagao Kazuya; Ono Koh; Horie Takahiro; Kinoshita Minako; Nishi Hitoo; Tamaki Yodo; Kuwabara Yasuhide; Iwanaga Yoshitaka; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2009

  
• PE-297 LOX-1 is Expressed in the Adipose Tissue of High-Fat Diet-Induced Obese Mice in Close Association with MCP-1(PE050,Diabetes 1 (H),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

  Takanabe Rieko; Ono Koh; Abe Yukiko; Wada Hiromichi; Takaya Tomohide; Satoh Noriko; Shimatsu Akira; Fujita Masatoshi; Sawamura Tatsuya; Hasegawa Koji

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2009

  
• FRS-064 NF-kB-dependent Induction of MicroRNA-146 Downregulates ErbB4 and may be Involved in the Deterioration of Cardiomyocyte Survival(FRS13,Novel Molecular Mechanisms of Heart Failure 2 (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

  Horie Takahiro; Ono Koh; Iwanaga Yoshitaka; Nishi Hitoo; Nagao Kazuya; Kinoshita Minako; Mori Rieko; Kuwabara Yasuhide; Hasegawa Koji; Kita Toru

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2009

  
• FRS-022 IGF Axis and Adiponectin as Prognostic Markers in Patients with Congestive Heart Failure(FRS5,Novel Biomarkers in Heart Failure (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

  Watanabe Shin; tamura toshihiro; Ono Koh; Kita Toru; Kimura Takeshi; Furukawa Yutaka

  Circulation journal : official journal of the Japanese Circulation Society, 01 Mar. 2009

  
• More- vs. Less-Intensive Lipid Lowering Therapy: Systematic Review and a Meta-Analysis.

  Toshiaki Toyota; Takeshi Morimoto; Yugo Yamashita; Hiroki Shiomi; Takao Kato; Takeru Makiyama; Yasuaki Nakagawa; Naritatsu Saito; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  CIRCULATION, Nov. 2018

  
• 活動性がんを有する患者に見つかった無症候性の下肢深部静脈血栓症の診療実態と予後

  山下侑吾; 塩見紘樹; 森本剛; 米田智也; 山田千夏; 牧山武; 加藤貴雄; 齋藤成達; 静田聡; 尾野亘; 木村剛

  心臓, 15 Jul. 2018

  
• 家族性高コレステロール血症に合併した労作性狭心症に対してPCIを施行した症例

  米田史哉; 塩見紘樹; 渡部宏俊; 豊田俊彬; 田崎淳一; 齋藤成達; 加藤貴雄; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2018

  
• Single-Session versus Staged Procedures for Elective Multi-Vessel Percutaneous Coronary Intervention

  Toshiaki Toyota; Takeshi Morimoto; Hiroki Shiomi; Kyohei Yamaji; Kenji Ando; Koh Ono; Satoshi Shizuta; Naritatsu Saito; Takao Kato; Shuichiro Kaji; Yutaka Furukawa; Yoshihisa Nakagawa; Kazushige Kadota; Minoru Horie; Takeshi Kimura

  CIRCULATION, Nov. 2017

  
• 当院における左心疾患を合併した強皮症関連肺動脈性肺高血圧症の臨床的特徴

  木下 秀之; 柳澤 洋; 吉藤 元; 北野 一樹; 田中 宗和; 今田 一彰; 吉田 雅晴; 辰島 正二郎; 森内 健史; 稲住 英明; 斎藤 成達; 中川 靖章; 尾野 亘; 木村 剛

  日本心臓病学会学術集会抄録, Sep. 2017

  
• 心臓サルコイドーシスにおける診断と免疫抑制療法

  柳澤 洋; 加藤 貴雄; 木下 秀之; 斎藤 成達; 静田 聡; 中川 靖章; 尾野 亘; 木村 剛

  第3回心筋症研究会, Apr. 2017, Peer-reviewed

  
• Molecular Basis of Cardiovascular Dysfunction in Metabolic Diseases 'Molecular Links between Lipid Metabolism and Heart Failure'

  Koh Ono

  第81回日本循環器学会Symposium 10, Mar. 2017

  
• 全身性強皮症に心アミロイドーシスを合併した1症例

  玉内華子; 今田一彰; 木下秀之; 北野一樹; 辰島正二郎; 柳澤洋; 森内健史; 今井逸雄; 齋藤成達; 牧山武; 中川靖章; 尾野亘; 木村剛

  日本循環器学会近畿地方会(Web), 2017

  
• Angiogenic Effects of Local Sustained Release of MicroRNA-126 in Murine Hindlimb Ischemia

  Shinichi Tsumaru; Kenji Minakata; Hidetoshi Masumoto; Koh Ono; Masayasu Izuhara; Kazuhiro Yamazaki; Tadashi Ikeda; Ryuzo Sakata

  CIRCULATION, Nov. 2016

  
• MicroRNA-33 Maintains Cellular Cholesterol Content in Fibroblasts and Fibrotic Response in Heart

  Masataka Nishiga; Takahiro Horie; Yasuhide Kuwabara; Osamu Baba; Tetsushi Nakao; Tomohiro Nishino; Daihiko Hakuno; Yasuhiro Nakashima; Kazuya Nagao; Koji Hasegawa; Toru Kita; Takeshi Kimura; Koh Ono

  CIRCULATION, Nov. 2016

  
• 今が旬!マイクロRNA・エクソソーム最前線 循環器領域におけるmiRNAの重要性

  尾野 亘

  血管医学, Oct. 2016

  
• Smoking Status-dependent Association between Monocyte Chemoattractant Protein-1 and Blood Pressure

  Maki Komiyama; Rieko Takanabe; Koh Ono; Sayaka Shimada; Hiromichi Wada; Hajime Yamakage; Noriko Satoh-Asahara; Masaharu Akao; Tatsuya Morimoto; Akira Shimatsu; Yuko Takahashi; Koji Hasegawa

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Oct. 2016

  
• Characteristics of Diagnostic Modalities and Corticosteroid Therapy in Cardiac Sarcoidosis

  Yanagisawa H; Kinoshita H; Kato T; Saito N; Shizuta S; Nakagawa Y; Kuwahara K; Ono K; Kimura T

  心不全学会 2016, Oct. 2016, Peer-reviewed

  
• Overexpression of the lincRNA Regulated by Pressure-Overload Leads to Cardiomyocyte Hypertrophy

  Yasuhide Kuwabara; Takahiro Horie; Osamu Baba; Masataka Nishiga; Tetsushi Nakao; Tomohiro Nishino; Fumiko Nakazeki; Satoshi Koyama; Takeshi Kimura; Koh Ono

  JOURNAL OF CARDIAC FAILURE, Sep. 2016

  
• Changes and Physiological Meanings of Serum microRNA during Therapeutic Course of Acute Heart Failure

  Satoshi Koyama; Takashi Kuragaichi; Yukihito Sato; Yasuhide Kuwabara; Takahiro Horie; Osamu Baba; Takeshi Kimura; Koh Ono

  JOURNAL OF CARDIAC FAILURE, Sep. 2016

  
• MicroRNA-33 Promotes Cardiac Fibrosis Through Maintaining Cellular Lipid Contents

  Masataka Nishiga; Takehiro Horie; Yasuhide Kuwabara; Kazuya Nagao; Takeshi Kimura; Koh Ono

  JOURNAL OF CARDIAC FAILURE, Sep. 2016

  
• Relationship between Systemic Remodeling of Extracellular Matrix (ECM) and Clinical Course of the Diseases in Heart Failure

  Kazuya Nagao; Hiroshi Yukawa; Kiyotaka Shimamura; Masataka Nishiga; Takahiro Horie; Koh Ono; Yukihito Sato; Tsukasa Inada; Toshinori Makita; Masaru Tanaka

  JOURNAL OF CARDIAC FAILURE, Sep. 2016

  
• COMPARISON OF SHORT- AND LONG-TERM MORTALITY BETWEEN ST-SEGMENT ELEVATION AND NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION

  Hidenori Yaku; Hiroki Shiomi; Takeshi Morimoto; Yugo Yamashita; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Mitsuru Abe; Miki Shinji; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Apr. 2016

  
• LONG-TERM CARDIAC AND NON-CARDIAC MORTALITY IN ST-ELEVATION ACUTE MYOCARDIAL INFARCTION PATIENTS WHO UNDERWENT PRIMARY PERCUTANEOUS CORONARY INTERVENTION: INSIGHT FROM THE CREDO-KYOTO AMI REGISTRY

  Yugo Yamashita; Hiroki Shiomi; Takeshi Morimoto; Hidenori Yaku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Mitsuru Abe; Satoshi Shizuta; Koh Ono; Takeshi Kimura

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Apr. 2016

  
• ｢miR-33a/bの生体における働きの解明と臨床応用への取り組み｣

  尾野 亘

  第53回日本臨床分子医学会 東京国際フォーラム, Apr. 2016

  
• MicroRNA-451 Exacerbates Lipotoxicity in Cardiomyocytes and High-Fat Diet-Induced Cardiac Hypertrophy in Mice through Suppression of the LKB1/AMPK Pathway

  Koh Ono

  AHA-JCS Joint Symposium “Functional Importance of Immune Cells in the Heart”, Mar. 2016

  
• Long Intergenic Noncoding RNA and Myogenin Circuitry Promotes Myoblast Differentiation.

  Yasuhide Kuwabara; Takahiro Horie; Shin Watanabe; Osamu Baba; Takeshi Kimura; Koh Ono

  Keystone Symposia, Noncoding RNAs in Health and Disease, Feb. 2016, Peer-reviewed

  
• MicroRNA-451 Aggravates Lipotoxic Cardiomyopathy through Suppression of the LKB1/AMP Pathway.

  Yasuhide Kuwabara; Takahiro Horie; Osamu Baba; Toru Kita; Takeshi Kimura; Koh Ono

  Basic Cardiovascular Sciences, Jul. 2015, Peer-reviewed

  
• 脂質恒常性維持におけるマイクロRNA-33の働き

  尾野 亘

  第1回J-ISCP学術集会 医学・薬学ジョイントシンポジウム 心血管疾患の創薬分子標的と再生・発生, Jun. 2015

  
• microRNA-33a/bによる細胞・臓器レベルの脂質代謝制御機構

  尾野 亘

  第58回日本糖尿病学会年次学術集会 シンポジウム25 脂質代謝研究の最前線, May 2015

  
• Future Perspective in Atherosclerosis Research: Seeking for Novel Therapeutic Targets against Cardiovascular Diseases ‘miR-33a/b as novel therapeutic targets for the treatment of cardiovascular diseases’

  Koh Ono

  第79回日本循環器学会 プレナリーセッション, Apr. 2015

  
• MicroRNA-33b Knock-in Mice for an Intron of Sterol Regulatory Element-Binding Factor 1 (Srebf1) Exhibit Reduced HDL-C in vivo

  Takahiro Horie; Tomohiro Nishino; Osamu Baba; Yasuhide Kuwabara; Tetsushi Nakao; Masataka Nishiga; Shunsuke Usami; Masayasu Izuhara; Fumiko Nakazeki; Yuya Ide; Satoshi Koyama; Masayuki Yokode; Toru Kita; Takeshi Kimura; Koh Ono

  CIRCULATION, Nov. 2014

  
• Self-rating Depression Scale Score as an Inverse and Independent Predictor of Successful Smoking Cessation with a Pharmacological Treatment for Nicotine Addiction

  Shuichi Ura; Hiromichi Wada; Noriko Satoh-Asahara; Masaharu Akao; Mitsuru Abe; Koh Ono; Tatsuya Morimoto; Akira Shimatsu; Yuko Takahashi; Koji Hasegawa

  CIRCULATION, Nov. 2014

  
• Serum levels of soluble Flt-1 are associated with cardiovascular events in patients with chronic kidney disease

  H. Wada; S. Ura; N. Masunaga; M. Akao; M. Ishii; T. Unoki; M. Abe; K. Ono; T. Morimoto; K. Hasegawa

  EUROPEAN HEART JOURNAL, Sep. 2014

  
• microRNA-33の動脈硬化・脂質制御における役割｣

  尾野 亘

  第46回日本動脈硬化学会総会・学術集会Featured Session：最先端の病態研究, Jul. 2014

  
• High impact of microRNA-33 on atherosclerosis and lipid metabolism

  Koh Ono

  第46回日本動脈硬化学会総会・学術集会、第9回五島雄一郎賞受賞講演, Jul. 2014

  
• MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo

  Takahiro Horie; Tomohiro Nishino; Osamu Baba; Yasuhide Kuwabara; Tetsushi Nakao; Masataka Nishiga; Shunsuke Usami; Masayasu Izuhara; Fumiko Nakazeki; Yuya Ide; Satoshi Koyama; Naoya Sowa; Naoya Yahagi; Hitoshi Shimano; Tomoyuki Nakamura; Koji Hasegawa; Noriaki Kume; Masayuki Yokode; Toru Kita; Takeshi Kimura; Koh Ono

  SCIENTIFIC REPORTS, Jun. 2014

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• 致死性不整脈症候群の病態解明に関する研究 臨床・基礎研究(ヒト疾患特異的人工多能性幹(iPS)細胞を用いた解析)

  木村 剛; 北 徹; 堀江 稔; 堀内 久徳; 尾野 亘; 牧山 武; 吉田 善紀

  医科学応用研究財団研究報告, Feb. 2014

  
• イントロンに存在するmicroRNA-33aおよび33bとそのホスト遺伝子SREBP2およびSREBP1間の脂質代謝クロストークの解明

  堀江 貴裕; 尾野 亘; 木村 剛

  医科学応用研究財団研究報告, 2013

  
• Soluble Vascular Endothelial Growth Factor Receptor-1 as a Predictor of Cardiovascular Events in Stable Outpatients with Chronic Kidney Disease

  Hiromichi Wada; Shuichi Ura; Nobutoyo Masunaga; Masaharu Akao; Mitsuru Ishii; Takashi Unoki; Mitsuru Abe; Yasuyo Nakajima; Mikihiko Kanasaki; Koh Ono; Tatsuya Morimoto; Noriko Satoh-Asahara; Akira Shimatsu; Koji Hasegawa

  CIRCULATION, Nov. 2012

  
• Circulating Levels of Vascular Endothelial Growth Factor-C are Closely Associated with Dyslipidemia and Atherosclerosis

  Shuichi Ura; Hiromichi Wada; Shuji Kitaoka; Noriko Satoh-Asahara; Takahiro Horie; Koh Ono; Tomohide Takaya; Rieko Takanabe-Mori; Masaharu Akao; Mitsuru Abe; Tatsuya Morimoto; Toshinori Murayama; Masayuki Yokode; Masatoshi Fujita; Akira Shimatsu; Koji Hasegawa

  CIRCULATION, Nov. 2012

  
• MicroRNA-33 Deficiency Reduced Atherosclerosis Formation In Vivo

  Takahiro Horie; Osamu Baba; Koh Ono; Yasuhide Kuwabara; Koji Hasegawa; Noriaki Kume; Masayuki Yokode; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2012

  
• MicroRNA 33 Deficiency in Leukocytes Reduced the Lipid Accumulation in Atherosclerotic Plaque in ApoE Knockout Mice

  Osamu Baba; Takahiro Horie; Yasuhide Kuwabara; Masayasu Izuhara; Shunsuke Usami; Tetsushi Nakao; Masataka Nishiga; Tomohiro Nishino; Naoya Sowa; Koji Hasegawa; Noriaki Kume; Masayuki Yokode; Toru Kita; Takeshi Kimura; Koh Ono

  CIRCULATION, Nov. 2012

  
• Neural Cell Adhesion Molecule is a Cardioprotective Factor Up-regulated In Rodent and Human Failing Heart

  Kazuya Nagao; Koh Ono; Yohei Yamauchi; Motoko Tokunaga; Kohei Fukuchi; Koji Uchiyama; Haruyasu Ito; Fujio Hayashi; Toshinori Makita; Tsukasa Inada; Masaru Tanaka; Takahiro Horie; Hitoo Nishi; Minako Kinoshita; Yasuhide Kuwabara; Katsumi Inoue; Takeshi Kimura

  CIRCULATION, Nov. 2012

  
• Serum Levels of Vascular Endothelial Growth Factor-C are Inversely Correlated with Future Cardiovascular Events

  Nobutoyo Masunaga; Hiromichi Wada; Masaharu Akao; Shuichi Ura; Mitsuru Ishii; Takashi Unoki; Mitsuru Abe; Mikhiko Kanasaki; Yasuyo Nakashima; Koh Ono; Tatsuya Morimoto; Noriko Asahara; Akira Shimatu; Koji Hasegawa

  CIRCULATION, Nov. 2012

  
• 血管内皮増殖因子Cと脂質異常・動脈硬化との関連

  浦 修一; 和田 啓道; 北岡 修二; 浅原 哲子; 堀江 貴裕; 尾野 亘; 赤尾 昌治; 阿部 充; 森本 達也; 村山 敏典; 横出 正之; 島津 章; 長谷川 浩二

  肥満研究, Sep. 2012

  
• MicroRNA-33 deficiency reduces atherosclerotic plaque progression in apoE knockout mice

  O. Baba; T. Horie; T. Nakamura; K. Hasegawa; N. Kume; M. Yokode; T. Kita; T. Kimura; K. Ono

  EUROPEAN HEART JOURNAL, Aug. 2012

  
• Interaction of S100A4 with p53 in fibroblasts modulates cardiac fibrosis through two distinct mechanisms

  Y. Tamaki; Y. Iwanaga; K. Ono; T. Shioi; S. P. Sheikh; N. Ambartsumian; E. Lukanidin; T. Koshimizu; S. Miyazaki; T. Kimura

  EUROPEAN HEART JOURNAL, Aug. 2012

  
• Serum MCP-1 levels are increased with duration of smoking and blood pressure in smoking patients

  Rieko Takanabe-Mori; Koh Ono; Hiromichi Wada; Hajime Yamakage; Noriko Satoh-Asahara; Akira Shimatsu; Yuko Takahashi; Koji Hasegawa

  CIRCULATION, May 2012

  
• 血管内皮増殖因子Cは脂質異常及び動脈硬化と関連している

  浦 修一; 和田 啓道; 北岡 修二; 佐藤 哲子; 堀江 貴裕; 尾野 亘; 高谷 智英; 森 利依子; 赤尾 昌治; 阿部 充; 森本 達也; 村山 敏典; 横出 正之; 藤田 正俊; 島津 章; 長谷川 浩二

  糖尿病, Apr. 2012

  
• LECTIN-LIKE OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR-1 (LOX-1) MAY BE INVOLVED IN SMOKING-INDUCED INFLAMMATION AT VESSEL WALLS

  Rieko Takanabe-Mori; Koh Ono; Hiromichi Wada; Tomohide Takaya; Hajime Yamakage; Noriko Satoh-Asahara; Akira Shimatsu; Yuko Takahashi; Masatoshi Fujita; Yoshiko Fujita; Tatsuya Sawamura; Koji Hasegawa

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Mar. 2012

  
• 人工弁置換術後の僧帽弁狭窄症に対してPTMCを施行した一例

  濱谷康弘; 齋藤成達; 夏秋政浩; 田崎淳一; 今井逸雄; 牧山武; 尾野亘; 塩井哲雄; 井上寛治; 木村剛

  日本循環器学会近畿地方会(Web), 2012

  
• MicroRNA 26b Encoded by the Intron of Small CTD Phosphatases (SCPs) 1 Has an Antagonistic Effect on its Host Gene and Suppresses Cardiac Hypertrophy

  Naoya Sowa; Koh Ono; Takahiro Horie; Koji Hasegawa; Takeshi Kimura

  CIRCULATION, Nov. 2011

  
• Soluble Vascular Endothelial Growth Factor Receptor-1 Serves as a Marker of Cardiovascular Risk in Chronic Kidney Disease Patients

  Hiromichi Wada; Shuichi Ura; Nobutoyo Masunaga; Masaharu Akao; Mitsuru Abe; Junko Funatsu; Yasuyo Nakajima; Mikihiko Kanasaki; Tameo Nakano; Koh Ono; Tatsuya Morimoto; Akira Shimatsu; Koji Hasegawa

  CIRCULATION, Nov. 2011

  
• CaMKK beta Contributes To Energy Supply In Adaptive Phase Of Pressure-overload-induced Heart Failure

  Shin Watanabe; Koh Ono; Takahiro Horie; Yasuhide Kuwabara; Osamu Baba; Yoshimasa Chujo; Takechi Kimura

  JOURNAL OF CARDIAC FAILURE, Sep. 2011

  
• Elevated microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular diseases indicate the myocardial damage

  Y. Kuwabara; K. Ono; T. Horie; H. Nishi; S. Watanabe; M. Kinoshita; O. Baba; T. Kita; T. Kimura

  EUROPEAN HEART JOURNAL, Aug. 2011

  
• alpha1-antitrypsin-low-density-lipoprotein serves as a marker of smoking-specific oxidative stress

  H. Wada; N. Satoh-Asahara; M. Akao; M. Abe; K. Ono; T. Morimoto; M. Fujita; A. Shimatsu; Y. Takahashi; K. Hasegawa

  EUROPEAN HEART JOURNAL, Aug. 2011

  
• CaMKK beta contributes to energy supply in adaptive phase of pressure-overload-induced heart failure

  S. Watanabe; K. Ono; T. Horie; H. Nishi; Y. Kuwabara; O. Baba; T. Kimura

  EUROPEAN HEART JOURNAL, Aug. 2011

  
• 市中獲得型MRSA感染性心内膜炎にて急性心不全をきたしたが,外科治療にて救命し得た一例

  吉澤尚志; 木村剛; 塩井哲雄; 尾野亘; 静田聡; 牧山武; 小笹寧子; 土井孝浩; 西山慶; 今井逸雄; 守上裕子

  日本循環器学会近畿地方会(Web), 2011

  
• Ca2+/Calmodulin-Dependent Kinase Kinsae Beta Contributes to Energy Supply in Adaptive Phase of Pressure-Overload-Induced Heart Failure

  Shin Watanabe; Koh Ono; Takahiro Horie; Hitoo Nishi; Minako Kinoshita; Yasuhide Kuwabara; Osamu Baba; Takeshi Kimura

  CIRCULATION, Nov. 2010

  
• MiR-146a-induced Inhibition of Neuregulin1-ErbB4 Pathway may be Involved in Deterioration of Cardiotoxicity under Concurrent Chemotherapy with Doxorubicin and Trastuzumab.

  Takahiro Horie; Koh Ono; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Shin Watanabe; Yasuhide Kuwabara; Yasuhiro Nakashima; Rieko Takanabe-Mori; Eiichiro Nishi; Koji Hasegawa; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2010

  
• Serum Adiponectin Levels are Increased by Pathologically Induced Left Ventricular Hypertrophy

  Hiromichi Wada; Masaharu Akao; Nobutoyo Masunaga; Tomohide Takaya; Rieko Takanabe-Mori; Mitsuru Abe; Junko Funatsu; Yasuyo Nakajima; Mikihiko Kanasaki; Genta Osakada; Tameo Nakano; Koh Ono; Noriko Satoh-Asahara; Akira Shimatsu; Koji Hasegawa

  CIRCULATION, Nov. 2010

  
• Microrna-27a Regulates Beta-Myosin Heavy Chain Gene Expression by Targeting Thyroid Hormone Receptor Beta 1 in Neonatal Rat Ventricular Myocytes

  Hitoo Nishi; Koh Ono; Takahiro Horie; Minao Kinoshita; Shin Watanabe; Yasuhide Kuwabara; Osamu Baba; Yasuhiro Nakashima; Kazuya Nagao; Rieko Takanabe-Mori; Koji Hasegawa; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2010

  
• Metastasis-associated Protein S100A4 Contributes to Cardiac Fibrosis through the Modulation of PTEN

  Yodo Tamaki; Yoshitaka Iwanaga; Junji Okuda; Shinichiro Niizuma; Tsuneaki Kawashima; Takao Kato; Yasutaka Inuzuka; Tetsuo Shioi; Koh Ono; Taka-aki Koshimizu; Shunichi Miyazaki; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2010

  
• MicroRNA-1 and MicroRNA-133a are Useful as Early Diagnostic Biomarkers in Patients with Acute Coronary Syndrome

  Yasuhide Kuwabara; Koh Ono; Takahiro Horie; Hitoo Nishi; Minako Kinoshita; Shin Watanabe; Yasuhiro Nakashima; Kazuya Nagao; Yoji Kojima; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2010

  
• Microrna 26b Family Encoded by the Introns of Small CTD Phosphatases (SCPs) 1 to 3 Suppresses Phenylephrine-Induced Cardiomyocyte Hypertrophy by Targeting TRPC3/6 and GATA4

  Koh Ono; Naoya Sowa; Takahiro Horie; Koji Hasegawa; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2010

  
• LOX-1 is Required for the Adiposal Expression of Proinflammatory Cytokines in High-fat Diet-induced Obese Mice

  Rieko Takanabe-Mori; Koh Ono; Naoya Sowa; Hiromichi Wada; Tomohide Takaya; Noriko Satoh-Asahara; Akira Shimatsu; Masatoshi Fujita; Tatsuya Sawamura; Koji Hasegawa

  CIRCULATION, Nov. 2010

  
• Ca2+/calmodulin-dependent kinase kinase beta contributes to energy supply in adaptive phase of pressure-overload-induced heart failure

  S. Watanabe; K. Ono; T. Horie; H. Nishi; Y. Kuwabara; T. Kimura

  EUROPEAN HEART JOURNAL, Sep. 2010

  
• Autophagy Reduces the Size of Acute Myocardial Infarction Induced by Permanent Coronary Artery Occlusion

  Hiromitsu Kanamori; Genzou Takemura; Kazuko Goto; Koh Ono; Kazuya Ngano; Takako Fujiwara; Hisayoshi Fujiwara; Mitsuru Seishima; Shinya Minatoguchi

  JOURNAL OF CARDIAC FAILURE, Sep. 2010

  
• 99mTc-MIBIのwashout亢進がMRI遅延造影と一致したARVDの一例

  加藤貴雄; 塩井哲雄; 横山信吾; 塩見紘樹; 土井孝浩; 静田聡; 尾野亘; 金尾昌太郎; 富樫かおり; 木村剛

  第20回日本心臓核医学会学術集会, Jun. 2010, Peer-reviewed

  
• Progranulin is Expressed in the Human Atherosclerotic Plaque and Reduces IL-8 Secretion from Smooth Muscle Cells, Endothelial Cells, And Macrophages

  KOJIMA Yoji; ONO Koh; INOUE Katsumi; YOSHIDA Yoshinori; NAKASHIMA Yasuhiro; NOBUYOSHI Masakiyo; KITA Toru; KIMURA Takeshi; TANAKA Makoto

  Circ J, 01 Mar. 2010, Peer-reviewed

  
• Neural Cell Adhesion Molecule is a Cardioprotective Factor Upregulated by Metabolic Stress

  Kazuya Nagao; Koh Ono; Takahiro Horie; Hitoo Nishi; Minako Kinoshita; Yoji Kojima; Yodo Tamaki; Yasuhide Kuwabara; Yoshitaka Iwanaga; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2009

  
• Aortic Stenosis and Acquired Type 2a von Willebrand Syndrome: Correlation Between Severity of Aortic Stenosis and Gastrointestinal Angiodysplasia(Heyde's Syndrome)

  Toshihiro Tamura; Tomohisa Tada; Koh Ono; Hisanori Horiuchi; Takeshi Kimura

  CIRCULATION, Nov. 2009

  
• MicroRNA-15b,-16,-195, And-424, Which Have the Same Seed Sequence, Regulate ADP-rybosylation Factor-like 2 And Cellular ATP Levels in Neonatal Rat Cardiac Myocytes

  Hitoo Nishi; Koh Ono; Takahiro Horie; Kazuya Nagao; Minako Kinoshita; Yasuhide Kuwabara; Rieko T. Mori; Koji Hasegawa; Genzou Takemura; Yoshitaka Iwanaga; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2009

  
• Let-7/miR-98 Family Regulates the Expression of GLUT4 by Targeting MEF-2C in Metabolic Control of Cardiomyocytes

  Naoya Sowa; Koh Ono; Takahiro Horie; Yoshitaka Iwanaga; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Rieko Takanabe-Mori; Toru Kita; Takeshi Kimura; Koji Hasegawa

  CIRCULATION, Nov. 2009

  
• Acute Doxorubicin Cardiotoxicity is Associated With miR-146a-induced Inhibition of the Neureglin-ErbB4 Pathway

  Takahiro Horie; Koh Ono; Yoshitaka Iwanaga; Hitoo Nishi; Kazuya Nagao; Mianko Kinoshita; Yasuhide Kuwabara; Rieko Takanabe-Mori; Koji Hasegawa; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2009

  
• The Identification of the Nkx2-5-regulated Genes Using Purified ES Cell-derived Cardiomyocytes

  Yasuhiro Nakashima; Koh Ono; Yoshinori Yoshida; Yoji Kojima; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2009

  
• Holes of Lectin-like Oxidized Low-density Lipoprotein (LDL) Receptor-1 for Maintenance of Normal Glucose Tolerance in Normal and Obese States

  Rieko Takanabe-Mori; Koh Ono; Naoya Sowa; Hiromichi Wada; Tomohide Takaya; Noriko Satoh; Akira Shimatsu; Masatoshi Fujita; Tatsuya Sawamura; Koji Hasegawa

  CIRCULATION, Nov. 2009

  
• MicroRNA-378, Which Exists Intronic Lesion of PGC-1beta, Deteriorate Cardiomyocyte Survival Under Oxidative Stress

  Yasuhide Kuwabara; Koh Ono; Takahiro Horie; Hitoo Nishi; Kazuya Nagao; Shin Watanabe; Yoji Kojima; Minako Kinosita; Rieko Mori; Toru Kita; Takeshi Kimura

  CIRCULATION, Nov. 2009

  
• Expression of LOX-1 (OLR1) is Markedly Increased in the Adipose Tissue of High-fat Diet-induced Obese Mice in Close Association With MCP-1

  Rieko Takanabe-Mori; Koh Ono; Yukiko Abe; Hiromichi Wada; Tomohide Takaya; Noriko Satoh; Akira Shimatsu; Masatoshi Fujita; Tatsuya Sawamura; Koji Hasegawa

  CIRCULATION, Nov. 2009

  
• MicroRNA-15b,-16,-195, and-424 are Involved in the Deterioration of Mitochondrial Function in Cardiomyocytes

  Hitoo Nishi; Koh Ono; Yoshitaka Iwanaga; Takahiro Horie; Kazuya Nagao; Genzou Takemura; Takanabe Rieko Mori; Koji Hasegawa; Toru Kita; Takeshi Kimura

  JOURNAL OF CARDIAC FAILURE, Sep. 2009

  
• PROGRANULIN IN ADVANCED HUMAN ATHEROSCLEROTIC PLAQUE

  Yoji Kojima; Koh Ono; Katsumi Inoue; Yasushi Takagi; Ken-Ichiro Kikuta; Masaki Nishimura; Yoshinori Yoshida; Yasuhiro Nakashima; Hironobu Matsumae; Yutaka Furukawa; Nobuhiro Mikuni; Masakiyo Nobuyoshi; Takeshi Kimura; Toru Kita; Makoto Tanaka

  JOURNAL OF VASCULAR RESEARCH, 2009

  
• Efficasy of Catheter Ablation for Atial Fibrillation with Sinus Node Dysfunction

  静田 聡; 土井 孝浩; 早野 護; 中尾 哲史; 西山 慶; 田村 俊寛; 当麻 正直; 尾野 亘; 北 徹; 木村 剛

  2009年3月 第73回 日本循環器学会学術総会 (大阪), 2009, Peer-reviewed

  
• Upregulation of MicroRNA 27a, which Downregulates Retinoid X Receptor alpha, Controls Cardiac Myosin Heavy Chain Gene Expression in Neonatal Rat Cardiomyocyte

  Hitoo Nishi; Koh Ono; Minako Kinoshita; Kazuya Nagao; Takahlro Horie; Rieko Takanabe; Koji Hasegawa; Yoshitaka Iwanaga; Toru Kita

  CIRCULATION, Oct. 2008

  
• Up-Regulated Expression of MicroRNA-143 In Association with Obesity in the Adipose Tissue of Mice Fed High Fat Diet

  Rieko Takanabe; Koh Ono; Tomohide Takaya; Takahiro Horie; Hiromichi Wada; Toru Kita; Akira Shimatsu; Koji Hasegawa

  CIRCULATION, Oct. 2008

  
• Cardiac-specific transcription in ES cells by Cdk9

  Shinji Kaichi; Tomohide Takaya; Tatsuya Morimoto; Yoichi Sunagawa; Teruhisa Kawamura; Koh Ono; Koji Hasegawa

  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Oct. 2008

  
• Overexpression of MicroRNA-1 in Mouse Embryonic Stem Cells Represses Myocardial Differentiation

  Tomohide Takaya; Teruhisa Kawamura; Koh Ono; Rieko Takanabe; Shinji Kaichi; Tatsuya Morimoto; Hiromichi Wada; Toru Kita; Akira Shimatsu; Koji Hasegawa

  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Oct. 2008

  
• Nf-kb-dependent Induction Of Microrna-146 Downregulates Erbb4 And May Be Involved In The Deterioration Of Cardiomyocyte Survival

  Takahiro Horie; Koh Ono; Yoshitaka Iwanaga; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Rieko Mori; Koji Hasegawa; Toru Kita

  CIRCULATION, Oct. 2008

  
• Neural Cell Adhesion Molecule Is Upregulated By Metabolic Stress And Enhances The Cardiomyocyte Survival Rate Through Neurite-cardiomyocyte Communication

  Kazuya Nagao; Koh Ono; Takahim Horie; Yoji Kojima; Hitoo Nish; Minako Kinoshita; Toru Kita

  CIRCULATION, Oct. 2008

  
• IGF axis and adiponectin as prognostic markers of patients with congestive heart failure

  S. Watanabe; T. Tamura; K. Ono; T. Kita; T. Kimura; Y. Furukawa

  EUROPEAN HEART JOURNAL, Sep. 2008

  
• MicroRNA-1の過剰発現はマウスES細胞の心筋分化を抑制する

  高谷 智英; 川村 晃久; 尾野 亘; 高鍋 利依子; 鷄内 伸二; 馬場 志郎; 平家 俊男; 中畑 龍俊; 森本 達也; 北 徹; 島津 章; 長谷川 浩二

  日本臨床分子医学会学術総会プログラム・抄録集, Jul. 2008

  
• MicroRNA-133 regulates the expression of CPT-1b and GLUT4 by targeting SRF and KLF15 and is involved in metabolic control in cardiac myocytes

  Hone Takahiro; Koh Ono; Yoshitaka Warraga; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Rieko Mori; Koji Hasegawa; Toru Kita

  CIRCULATION, Oct. 2007

  
• Roles of muscle-specific MicroRNAs during differentiation of mouse embryonic stem cells into cardiac myocytes

  Tomohide Takaya; Teruhisa Kawamura; Koh Ono; Rieko Takanabe-Mori; Shinji Kaichi; Toru Kita; Hiromichi Wade; Tatsuya Morimoto; Akira Shimatsu; Koji Hasegawa

  CIRCULATION, Oct. 2007

  
• MicroRNA-206 controls cardiac myosin heavy chain gene expression by targeting RXR-alpha

  Hitoo Nishi; Koh Ono; Yoshitaka Iwanaga; Takahiro Horie; Minako Kinoshita; Kazuya Nagao; Rieko Mori; Koji Hasegawa; Toru Kita

  CIRCULATION, Oct. 2007

  
• Serotonin in adipose tissue acts as an autocrine factor required for adipocyte differentiation and lipolysis

  Koh Ono; Takahiro Horie; Yukiko Abe; Teruhisa Kawamura; Minako Kinoshita; Hitoo Nishi; Kazuya Nagao; Noriko Satoh; Akira Shimatsu; Toru Kita; Koji Hasegawa

  CIRCULATION, Oct. 2007

  
• Oxidative stress induces GLUT4 translocation by dual AMPK kinase activation in cardiac myocytes

  Horie Takahiro; Koh Ono; Yukiko Abe; Teruhisa Kawamura; Hiromichi Wada; Minako Kinoshita; Kazuya Nagao; Hitoo Nishi; Akira Shimatsu; Toru Kita; Koji Hasegawa

  CIRCULATION, Oct. 2007

  
• Chronic administration of endogenous inotropic peptide, apelin, prevents left ventricular remodeling and improves survival in hypertensive rats with heart failure

  Yodo Tamaki; Yoshitaka Iwanaga; ShiniGhiro Niizuma; Tsuneaki Kawashima; Takao Kato; Yasutaka Inuzuka; Koh Ono; Tetsuo Shioi; Toru Kita

  CIRCULATION, Oct. 2007

  
• C-C chemokine receptor-2 inhibitor ameliorates insulin resistance and hepatic steatosis in db/db mice.

  Yukinori Tamura; Hidenon Arai; Masayuki Sugimoto; Toshinori Murayama; Yukihiko Ueda; Hiroshi Kanamori; Koh Ono; Hiroyuki Ariyasu; Takashi Akamizu; Toru Kita; Masayuki Yokode

  CIRCULATION, Oct. 2007

  
• Mulberry leaf ameliorates the production of adipocytokines by inhibiting oxidative stress in white adipose tissue in db/db mice

  Masayuki Sugimoto; Hidenori Arai; Yukinori Tamura; Toshinori Murayama; Koh Ono; Hiroyuki Ariyasu; Takashi Alkamizu; Toru Kita; Kaeko Kamei; Masayuki Yokode

  CIRCULATION, Oct. 2007

  
• Activation of smad transcriptional corepressor TGIF by insulin is required for adipocyte differentiation

  Hone Takahiro; Koh Ono; Yukiko Abe; Teruhisa Kawamura; Akira Shimatsu; Toru Kita; Koji Hasegawa

  CIRCULATION, Oct. 2007

  
• Identification of signaling pathways that mediate the oxidative stress-induced translocation of myocardial GLUT4 using a novel lenti-viral mediated GLUT4 reporter gene

  Takahiro Horie; Koh Ono; Yukiko Abe; Teruhisa Kasamura; Akira Shimatsu; Koji Hasegawa; Toru Kita

  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Dec. 2006

  
• Identification of signaling pathways that mediate the oxidative stress-induced translocation of myocardial GLUT4 using a novel lenti-viral-mediated GLUT4 reporter gene

  Takahiro Horie; Koh Ono; Yukiko Abe; Teruhisa Kawamura; Akira Shimatsu; Toru Kita; Koji Hasegawa

  JOURNAL OF CARDIAC FAILURE, Oct. 2006

  
• Identification of GATA-4 acetylation targets by p300 during myocardial cell hypertrophy

  Tomohide Takaya; Teruhisa Kawamura; Tatsuya Morimoto; Koh Ono; Toru Kita; Akira Shimatsu; Koji Hasegawa

  CIRCULATION, Oct. 2006

  
• Soluble Flk-1 and soluble Tie-2, endogenous inhibitors of endothelial cell-specific angiogenic signals, are increased in serum of patients with metabolic syndrome.

  Hiromichi Wada; Koh Ono; Noriko Satoh; Sachika Kameda; Daisuke Shinjo; Yukiko Abe; Teruhisa Kawamura; Tatsuya Morimoto; Tameo Nakano; Akira Shimatsu; Masatoshi Fujita; Koji Hasegawa

  CIRCULATION, Oct. 2006

  
• Identification of signaling pathways that mediate the oxidative stress-induced translocation of myocardial GLUT4 using a novel lenti viral-mediated GLUT4 reporter gene

  Takahiro Horie; Koh Ono; Yukiko Abe; Teruhisa Kawamura; Akira Shimatsu; Koji Hasegawa; Toru Kita

  CIRCULATION, Oct. 2006

  
• Adipocyte-derived serotonin regulates adipocyte differentiation via an autocrine/paracrine mechanism

  Koh Ono; Takahiro Horie; Yukiko Abe; Teruhisa Kawamura; Akira Shimatsu; Koji Hasegawa; Toru Kita

  JOURNAL OF CARDIAC FAILURE, Oct. 2006

  
• Prognostic value of serum adiponectin level in patients with congestive heart failure

  T. Tamura; Y. Furukawa; R. Taniguchi; K. Ono; T. Kita; T. Kimura

  EUROPEAN HEART JOURNAL, Aug. 2006

  
• p300-mediated inhibition of doxorubicin-induced myocardial cell apoptosis involves ubiquitin-dependent p53 degradation

  T Morimoto; K Ono; T Kawamura; T Kita; K Hasegawa

  JOURNAL OF CARDIAC FAILURE, Dec. 2005

  
• Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling following myocardial infarction in adult mice in vivo

  S Miyamoto; T Kawamura; T Morimoto; K Ono; Y Kawase; T Kita; K Hasegawa

  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, Dec. 2005

  
• A natural histone acetyltransferase inhibitor, garcinol, represses pherrylephrine-induced hypertrophic responses in cardiac myocytes

  T Kawamura; T Morimoto; K Ono; T Kita; K Hasegawa

  CIRCULATION, Oct. 2005

  
• Enkephalin is predominantly expressed in the adipose tissue of diabetes with obesity and is required for differentiation into mature adipocytes

  K Ono; Y Abe; T Morimoto; T Kita; A Shimatsu; K Hasegawa

  CIRCULATION, Oct. 2005

  
• A continuous low-dose, but not high-dose of granulocyte-colony stimulating factor therapy in cardiomyopathic hamsters with end-stage

  T Kawamura; S Miyamoto; K Ono; T Morimoto; H Wada; Y Abe; M Kano; T Kuwaki; H Nomura; T Kita; K Hasegawa

  CIRCULATION, Oct. 2005

  
• Screening of circulating cytokines for novel biological markers in patients with congestive heart failure

  T. Tamura; Y. Furukawa; K. Ono; T. Kita; T. Kimura

  EUROPEAN HEART JOURNAL, Sep. 2005

  
• Differentiation of mouse and monkey ES cells into cardiac myocytes and cell implantation for myocardial regeneration therapy

  T Kawamura; K Ono; N Ehara; M Hoseinkani; T Morimoto; R Taniguchi; Y Furukawa; T Kita; H Suemori; N Nakatsuji; K Hasegawa

  CIRCULATION RESEARCH, Jul. 2005

  
• Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling following myocardial infarction in adult mice in vivo

  S Miyamoto; T Kawamura; T Morimoto; K Ono; Y Kawase; T Kita; K Hasegawa

  CIRCULATION RESEARCH, Jul. 2005

  
• 再生医療 カニクイザルES細胞を用いた心筋再生療法

  長谷川 浩二; 川村 晃久; 尾野 亘; Hosseinkhani Mohsen; 古川 裕; 日高 京子; 森崎 隆幸; 平家 俊男; 中畑 龍俊; 末盛 博文; 中辻 憲夫; 北 徹

  日本臨床分子医学会学術総会プログラム・抄録集, Jul. 2005

  
• Hypertrophic stimuli induce association of mineralocorticoid receptor with a transcriptional coactivator p300 in cardiac myocytes

  T Kawamura; K Ono; T Morimoto; Y Yoshida; Y Abe; N Sowa; K Hasegawa

  CIRCULATION, Oct. 2004

  
• Leptin induces elongation of cardiac myocytes through the activation of JAK2/STAT3 cascade

  Y Abe; K Ono; T Kawamura; A Shimazu; K Hasegawa; T Morimoto; S Miyamoto

  CIRCULATION, Oct. 2004

  
• Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling following myocardial infarction in adult mice in vivo

  S Miyamoto; T Morimoto; K Ono; Y Kawase; T Kita; K Hasegawa

  CIRCULATION, Oct. 2004

  
• ヒストン脱アセチル化酵素の阻害は心筋細胞への分化を亢進する

  川村 晃久; 尾野 亘; 森本 達也; 長谷川 浩二; 日高 京子; 森崎 隆幸; 平家 俊男; 中畑 龍俊; 末盛 博文; 中辻 憲夫; 北 徹

  日本臨床分子医学会学術総会プログラム・抄録集, Jul. 2004

  
• Gene expression of cardiac mast cell chymase and tryptase in a murine model of heart failure caused by viral myocarditis (vol 67, pg 881, 2003)

  K Kitaura-Inenaga; M Hara; K Higuchi; K Yamamoto; A Yamaki; K Ono; A Nakano; M Kinoshita; S Sasayama; A Matsumori

  CIRCULATION JOURNAL, Dec. 2003

  
• A promoter variant of heme oxygenase-1 gene may reduce the incidence of ischemic heart disease through its activity in Japanese

  K Ono; Y Goto; S Takagi; S Baba; M Terashima; Y Tsutsumi; S Suzuki; H Nonogi; N Iwai

  CIRCULATION, Nov. 2002

  
• Elucidation of necrosis signaling pathway using a functional gene identification approach

  K Ono; XF Wang; JH Han

  CIRCULATION, Oct. 2001

  
• Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric oxide synthase in a murine model of viral myocarditis. (vol 33, pg 1400, 1999)

  A Iwasaki; A Matsumori; Y Takehiko; T Shioi; W Wang; K Ono; R Nishio; M Okada; S Sasayama

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Aug. 1999

  
• NF-kappa B activation and enhanced cytokine gene expression occurs in the non-infarcted myocardium of rat hearts

  K Ono; T Shioi; Y Furukawa; A Nakano; A Matsumori

  CIRCULATION, Oct. 1998

  
• Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric bride synthase in a murine model of viral myocarditis

  A Iwasaki; K Ono; R Nishio; M Okada; A Matsumori

  CIRCULATION, Oct. 1998

  
• Treatment with endothelin receptor antagonist has a cardioprotective effect without affecting viral replication in a murine model of myocarditis

  K Ono; A Matsumori

  CIRCULATION, Oct. 1998

  
• Hepatocyte growth factor is a major mediator in heparin-induced angiogenesis.

  M Okada; K Ono; M Takahashi; T Miyamoto; A Matsumori

  CIRCULATION, Oct. 1998

  
• Hypertrophic cardiomyopathy associated with hepatitis C virus infection

  A Matsumori; Y Matoba; R Nishio; T Shioi; K Ono; T Kakio; N Ohashi; M Hara

  CIRCULATION, Oct. 1997

  
• Anti monocyte chemotactic and activating factor monocyte chemoattractant protein-1 antibody inhibits neointimal hyperplasia in rats

  Y Furukawa; K Ono; T Shioi; K Matsushima; A Matsumori

  CIRCULATION, Oct. 1997

  
• Recombinant rat hepatocyte growth factor induces capillary endothelial regeneration in a rat model of myocardial ischemia and reperfusion

  K Ono; T Shioi; Y Furukawa; A Matsumori

  CIRCULATION, Oct. 1997

  
• P338 圧負荷心における炎症性サイトカイン発現 : 代償性心肥大から心不全への移行における意義

  塩井 哲雄; 松森 昭; 木原 康樹; 猪子 森明; 尾野 亘; 岩崎 篤志; 篠山 重威

  Japanese circulation journal, 05 Mar. 1997

  
• Fas ligand Fas system is more important in apoptosis than tumor necrosis factor-alpha in congestive heart failure induced by viral myocarditis in mice

  T Yamada; K Ono; A Matsumori; S Sasayama

  CIRCULATION, Oct. 1996

  
• Autophagy limits acute myocardial infarction induced by permanent coronary artery occlusion

  Hiromitsu Kanamori; Hiromitsu Kanamori; Genzou Takemura; Kazuko Goto; Rumi Maruyama; Koh Ono; Kazuya Nagao; Akiko Tsujimoto; Atsushi Ogino; Toshiaki Takeyama; Tomonori Kawaguchi; Takatomo Watanabe; Masanori Kawasaki; Takako Fujiwara; Hisayoshi Fujiwara; Mitsuru Seishima; Shinya Minatoguchi

  American Journal of Physiology - Heart and Circulatory Physiology, 1978