Basic Information

Faculty

• 医学部

Professional Memberships

• Society for Neuroscience
• 日本解剖学会
• PHYSIOLOGICAL SOCIETY OF JAPAN
• THE JAPAN NEUROSCIENCE SOCIETY
• The Japanese society for motor contro;

Academic Degree

• 修士（理学）(東京大学)
• 博士（医学）(東京医科歯科大学)

Academic Resume (Graduate Schools)

• 東京大学, 大学院理学系研究科修士課程生物化学専攻, 修了
• 東京医科歯科大学, 大学院医歯学総合研究科博士課程生体支持組織学系専攻, 修了

Academic Resume (Undergraduate School/Majors)

• 東京大学, 理学部生物化学科, 卒業

Research History

• From May 2020, To Present

  Kyoto University, 大学院医学研究科 脳統合イメージング分野, 准教授
• From Apr. 2014, To May 2020

  国立精神・神経医療研究センター, 神経研究所, 室長
• From Apr. 2013, To Mar. 2014

  Yokohama City University, 医学部, 助教
• From Apr. 2007, To Mar. 2013

  National Institute for Physiological Sciences, 研究員
• From Apr. 2004, To Sep. 2006

  東京医科歯科大学 医歯(薬)学総合研究科, 研究員
• From Apr. 2002, To Mar. 2004

  日本学術振興会, 学術振興会特別研究員（DC2）

Profile

• Profile

  運動に伴って行われる感覚情報の調節のメカニズムについて、霊長類からの網羅的な記録を計算論的手法を用いて研究を行っています。
  
  これまでに、分子生物学・解剖学・生理学といった多岐にわたる分野を渡り歩いてきました。幅広い分野での経験を絡めて、深く掘り下げた研究を行いたいと思っています。

Language of Instruction

• Japanese

ID,URL

• J-Global ID

  201101086153940620

• External link

  https://nrid.nii.ac.jp/ja/nrid/1000090376723/

researchmap URL

• https://researchmap.jp/tatsuya_umeda

Research

Research Interests

• マーモセット
• dorsal root ganglion
• spinal cord
• multichannel recording
• スライス培養
• 2光子顕微鏡
• GFP

Research Areas

• Life sciences, Clinical pharmacy
• Life sciences, Physiology
• Life sciences, Neuroscience - general

Papers

• Future spinal reflex is embedded in primary motor cortex output.

  Tatsuya Umeda; Osamu Yokoyama; Michiaki Suzuki; Miki Kaneshige; Tadashi Isa; Yukio Nishimura

  Science advances, 20 Dec. 2024, Peer-reviewed, Lead author, Corresponding author

  Access this paper :

  
• fMRI analysis of prosthetic hand rehabilitation using a brain-machine interface

  Hiroshi Yokoi; Keita Sato; Souichiro Morishita; Tatuhiro Nakamura; Ryu Kato; Tatsuya Umeda; Hidenori Watanabe; Yukio Nishimura; Tadashi Isa; Katsunori Ikoma; Tamaki Miyamoto; Osamu Yamamura

  Advances in Therapeutic Engineering, 01 Jan. 2012

  
• Time course of recovery of different motor functions following a reproducible cortical infarction in non-human primates

  Akito Kosugi; Yosuke Saga; Moeko Kudo; Masashi Koizumi; Tatsuya Umeda; Kazuhiko Seki

  Frontiers in Neurology, 09 Feb. 2023, Peer-reviewed

  
• Temporal dynamics of the sensorimotor convergence underlying voluntary limb movement

  Tatsuya Umeda; Tadashi Isa; Yukio Nishimura

  Proceedings of the National Academy of Sciences, 29 Nov. 2022, Peer-reviewed, Lead author, Corresponding author

  Access this paper :

  
• Optogenetic recruitment of spinal reflex pathways from large-diameter primary afferents in non-transgenic rats transduced with AAV9/Channelrhodopsin 2.

  Shinji Kubota; Wupuer Sidikejiang; Moeko Kudo; Ken-Ichi Inoue; Tatsuya Umeda; Masahiko Takada; Kazuhiko Seki

  The Journal of physiology, Oct. 2019, Peer-reviewed

  
• Decoding of muscle activity from the sensorimotor cortex in freely behaving monkeys

  Umeda, T; Koizumi, M; Katakai, Y; Saito, R; Seki, K

  NeuroImage, Aug. 2019, Peer-reviewed, Lead author, Corresponding author

  
• The somatosensory cortex receives information about motor output

  Umeda, T; Isa, T; Nishimura, Y; corresponding author

  Science Advances, Jul. 2019, Peer-reviewed, Lead author, Corresponding author

  
• Causal Link between the Cortico-Rubral Pathway and Functional Recovery through Forced Impaired Limb Use in Rats with Stroke

  Akimasa Ishida; Kaoru Isa; Tatsuya Umeda; Kazuto Kobayashi; Kenta Kobayashi; Hideki Hida; Tadashi Isa

  JOURNAL OF NEUROSCIENCE, Jan. 2016, Peer-reviewed

  
• Engineering approach for functional recovery based on body image adjustment by using biofeedback of electrical stimulation

  Hiroshi Yokoi; Yuki Sato; Minako Suzuki; Yoshiko Yabuki; Tatsuhiro Nakamura; Takashi Mori; Soichiro Morishita; Ryu Kato; Osamu Yamamura; Masafumi Kubota; Tomoko Kamisawa; Chiaki Igarashi; Tadashi Isa; Tatsuya Umeda; Hidenori Watanabe; Yukio Nishimura; Katsunori Ikoma; Tamaki Miyamoto

  Clinical Systems Neuroscience, 01 Jan. 2015, Peer-reviewed

  
• Decoding of the spike timing of primary afferents during voluntary arm movements in monkeys

  Tatsuya Umeda; Hidenori Watanabe; Masa-aki Sato; Mitsuo Kawato; Tadashi Isa; Yukio Nishimura

  FRONTIERS IN NEUROSCIENCE, May 2014, Peer-reviewed, Lead author, Corresponding author

  
• Reorganization of sensory pathways after neonatal hemidecortication in rats

  Oraphan Wanakhachornkrai; Tatsuya Umeda; Kaoru Isa; Mayuree H. Tantisira; Boonyong Tantisira; Tadashi Isa

  NEUROSCIENCE RESEARCH, Feb. 2014, Peer-reviewed, Corresponding author

  
• Reorganization of motor circuits after neonatal hemidecortication

  Tatsuya Umeda; Kengo Funakoshi

  NEUROSCIENCE RESEARCH, Jan. 2014, Peer-reviewed, Lead author, Corresponding author

  
• A pilot study for the development of a portable leukocytapheresis system

  NOISHIKI Yasuharu; TAKEDA Yuma; UMEDA Tatsuya; ATOBE Yoshitoshi; TAKEDA Akihito; KANEKO Kanichiro; TAKIGUCHI Masahito; FUNAKOSHI Kengo

  Japanese Journal of Apheresis, 2014, Peer-reviewed

  
• Estimation of Firing Pattern of Primary Afferents from Joint Kinematics During Voluntary Arm Movements of Monkeys

  Umeda Tatsuya; Sato Masa-aki; Kawato Mitsuo; Isa Tadashi; Nishimura Yukio

  BME, 2013

  
• Population Coding of Forelimb Joint Kinematics by Peripheral Afferents in Monkeys

  Tatsuya Umeda; Kazuhiko Seki; Masa-aki Sato; Yukio Nishimura; Mitsuo Kawato; Tadashi Isa

  PLOS ONE, Oct. 2012, Peer-reviewed, Lead author, Corresponding author

  
• Differential contributions of rostral and caudal frontal forelimb areas to compensatory process after neonatal hemidecortication in rats

  Tatsuya Umeda; Tadashi Isa

  EUROPEAN JOURNAL OF NEUROSCIENCE, Nov. 2011, Peer-reviewed, Lead author, Corresponding author

  
• Formation of Descending Pathways Mediating Cortical Command to Forelimb Motoneurons in Neonatally Hemidecorticated Rats

  Tatsuya Umeda; Masahito Takahashi; Kaoru Isa; Tadashi Isa

  JOURNAL OF NEUROPHYSIOLOGY, Sep. 2010, Peer-reviewed, Lead author, Corresponding author

  
• Classification analysis of Monkey ECoG data for reaching motion

  Keita Sato; Tatsuhiro Nakamura; Soichiro Morishita; Tatsuya Umeda; Hidenori Watanabe; Ryu Kato; Tadashi Isa; Hiroshi Yokoi

  UEC & SJTU Proceedings of 3rd International Symposium on Robot and Artificial Intelligence, Jun. 2010

  
• Large-scale reorganization of corticofugal fibers after neonatal hemidecortication for functional restoration of forelimb movements

  Masahito Takahashi; Anusara Vattanajun; Tatsuya Umeda; Kaoru Isa; Tadashi Isa

  EUROPEAN JOURNAL OF NEUROSCIENCE, Nov. 2009, Peer-reviewed, Lead author

  
• Kinase-Dead Knock-In Mouse Reveals an Essential Role of Kinase Activity of Ca2+/Calmodulin-Dependent Protein Kinase II alpha in Dendritic Spine Enlargement, Long-Term Potentiation, and Learning

  Yoko Yamagata; Shizuka Kobayashi; Tatsuya Umeda; Akihiro Inoue; Hiroyuki Sakagami; Masahiro Fukaya; Masahiko Watanabe; Nobuhiko Hatanaka; Masako Totsuka; Takeshi Yagi; Kunihiko Obata; Keiji Imoto; Yuchio Yanagawa; Toshiya Manabe; Shigeo Okabe

  JOURNAL OF NEUROSCIENCE, Jun. 2009, Peer-reviewed

  
• Kinase activity of CaMKII alpha is essential for structural, functional and behavioral expression of synaptic memory

  Yoko Yamagata; Shizuka Kobayashi; Tatsuya Umeda; Akihiro Inoue; Hiroyuki Sakagami; Masahiro Fukaya; Masahiko Watanabe; Nobuhiko Hatanaka; Masako Totsuka; Takeshi Yagi; Kunihiko Obata; Keiji Imoto; Yuchio Yanagawa; Toshiya Manabe; Shigeo Okabe

  NEUROSCIENCE RESEARCH, 2009, Peer-reviewed

  
• Simultaneous observation of stably associated presynaptic varicosities and postsynaptic spines: morphological alterations of CA3-CA1 synapses in hippocampal slice cultures

  T Umeda; T Ebihara; S Okabe

  MOLECULAR AND CELLULAR NEUROSCIENCE, Feb. 2005, Peer-reviewed, Lead author

  
• Electroporation-mediated gene transfer system applied to cultured CNS neurons

  Kawabata, I; T Umeda; K Yamamoto; S Okabe

  NEUROREPORT, Apr. 2004, Peer-reviewed

  
• Postsynaptic expression of a new calcium pathway in hippocampal CA3 neurons and its influence on mossy fiber long-term potentiation

  W Kakegawa; N Yamada; M Iino; K Kameyama; T Umeda; K Tsuzuki; S Ozawa

  JOURNAL OF NEUROSCIENCE, Jun. 2002, Peer-reviewed

  

Misc.

• サル硬膜下電位からのリーチングタスクの状態判別率向上を目指した次元圧縮法

  坂井郁也; 森下壮一郎; 西村幸男; 渡辺秀典; 加藤龍; 梅田達也; 伊佐正; 横井浩史

  自律分散システム・シンポジウム(CD-ROM), 2014

  
• Optogenetic activation of cutaneous and proprioceptive afferent in the rat sciatic nerve

  Kubota S; Sidikejiang W; Kudoh M; Inoue K; Umeda T; Takada M; Seki K

  Neuroscience 2018(2018/11/4, San Diego, USA）, Nov. 2018

  
• In vivo electrophysiological evaluation of chanelrhodopsin-2-expressed dorsal root ganglion neurons in adults rats.

  Seki K; S Wupuer; Umeda T; Inoue K; Kudo M; Takada M

  第39回日本神経科学大会 (2017/07/20-22, 横浜), Jul. 2016

  
• Canonical correlation analysis (CCA) of multi-joint motion (JM) and dorsal root ganglion (DRG) neuronal activities

  Jun Morimoto; Tatsuya Umeda; Yukio Nishimura; Tadashi Isa; Mitsuo Kawato; Keisuke Toyama

  NEUROSCIENCE RESEARCH, 2011

  
• Extracting neuronal ensemble from dorsal root ganglia to encode hand/arm trajectories in monkeys

  Tatsuya Umeda; Masa-aki Sato; Mitsuo Kawato; Tadashi Isa

  NEUROSCIENCE RESEARCH, 2011

  
• Coding of hand/arm trajectories by neuronal activity in dorsal root ganglia of monkeys

  Tatsuya Umeda; Tomoya Sakatani; Jun Morimoto; Okito Yamashita; Masaaki Satoh; Kazuhiko Seki; Mitsuo Kawato; Tadashi Isa

  NEUROSCIENCE RESEARCH, 2010

  
• Estimation of common features shared by multiple sensor data including neural recordings

  Jun Morimoto; Tatsuya Umeda; Tomoya Sakatani; Tadashi Isa; Mitsuo Kawato

  NEUROSCIENCE RESEARCH, 2010

  
• THE ROLE OF KINASE ACTIVITY OF Ca2+/CALMODULIN-DEPENDENT PROTEIN KINASE II IN HIPPOCAMPAL SYNAPTIC PLASTICITY AND LEARNING

  Yoko Yamagata; Shizuka Kobayashi; Tatsuya Umeda; Akihiro Inoue; Hiroyuki Sakagami; Masahiro Fukaya; Masahiko Watanabe; Nobuhiko Hatanaka; Masako Totsuka; Takeshi Yagi; Kunihiko Oabata; Keiji Imoto; Yuchio Yanagawa; Toshiya Manabe; Shigeo Okabe

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009

  
• COMPENSATORY CORTICOMOTONEURONAL CONNECTIONS IN RATS WITH NEONATAL HEMIDECORTICATION

  Tatsuya Umeda; Masahito Takahashi; Anusara Vattanajun; Kaoru Isa; Tadashi Isa

  JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009

  
• Reorganization of corticospinal tract in rats with neonatal hemidecortication

  Tatsuya Umeda; Kaoru Isa; Tadashi Isa

  NEUROSCIENCE RESEARCH, 2008

  
• Large-scale change in the corticofugal projections in rats with neonatal hemi-decortication

  Masahito Takahashi; Anusara Vattanajun; Tatsuya Umeda; Kaoru Isa; Tadashi Isa

  NEUROSCIENCE RESEARCH, 2007

  
• Visualizing synapse formation and remodeling: recent advances in real-time imaging of CNS synapses

  T Umeda; S Okabe

  NEUROSCIENCE RESEARCH, Aug. 2001

  

Books and Other Publications

• fMRI Analysis of Prosthetic Hand Rehabilitation Using a Brain-Machine Interface

  Yokoi, H; Sato, K; Morishita, S; Nakamura, T; Kato, R; Umeda, T; Watanabe, H; Nishimura, Y; Isa, T; Ikoma, K; Miyamoto, T; Yamamura, O, Joint work

  Advance in Therapeutic Engineering, 2012, Not refereed

  

External funds: Kakenhi

• Neural mechanism of BMI rehabilitation in monkeys with cerebral infarction

  Grant-in-Aid for Scientific Research (C)

  Basic Section 59010:Rehabilitation science-related

  Kyoto University;National Center of Neurology and Psychiatry

  Umeda Tatsuya

  From 01 Apr. 2019, To 31 Mar. 2022, Project Closed

  マーモセット;皮質脳波;上肢運動;リーチング;脳梗塞;ECoG;末梢感覚神経;筋活動

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K11384/
• Analysis of parallel computing of the corticospinal pathways in the primates

  Grant-in-Aid for Scientific Research (C)

  National Center of Neurology and Psychiatry

  Tatsuya Umeda

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  皮質脊髄路;マカクサル;一次運動野;アデノ随伴ウイルス;premotor neuron

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K06749/
• Comprehensive analysis of cortico-motoneuronal pathways of adult rats using virus vectors

  Grant-in-Aid for Young Scientists (B)

  National Center of Neurology and Psychiatry;Yokohama City University

  Tatsuya UMEDA

  From 01 Apr. 2013, To 31 Mar. 2015, Project Closed

  運動ニューロン;ラット;ウイルスベクター;脊髄;遺伝子発現

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25871057/
• LTP形成におけるシナプス前部・後部の構造変化の解析

  Grant-in-Aid for Young Scientists (B)

  Tokyo Medical and Dental University

  梅田 達也

  From 01 Apr. 2005, To 31 Mar. 2007, Project Closed

  海馬;LTP;スライス培養;GFP;2光子顕微鏡

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17700331/
• Elucidating the neural mechanisms of perceiving object size by manual exploration

  Grant-in-Aid for Scientific Research (B)

  Basic Section 61060:Kansei informatics-related

  Kyoto University

  梅田 達也

  From 01 Apr. 2024, To 31 Mar. 2027, Granted

  マーモセット;体性感覚野;光遺伝学;立体知覚;手探り

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K03026/
• Neural information dynamics in a canonical microcircuit of the cerebral cortex.

  Grant-in-Aid for Transformative Research Areas (A)

  Transformative Research Areas, Section (IV)

  Kyoto University

  梅田 達也

  From 01 Apr. 2024, To 31 Mar. 2026, Granted

  マーモセット;体性感覚野;光遺伝学;超多極電極

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-24H02166/