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Okamura, Hitoshi

Graduate School of Medicine, Medicine

Okamura, Hitoshi
list
    Last Updated :2025/05/02

    Basic Information

    Faculty

    • 薬学部

    Academic Degree

    • 医学博士(京都府立医科大学)

    Academic Resume (Undergraduate School/Majors)

    • 京都府立医科大学, 卒業

    Language of Instruction

    • English

    ID,URL

    Website(s) (URL(s))

    researchmap URL

    list
      Last Updated :2025/05/02

      Research

      Research Topics, Overview of the research

      • Research Topics

        Molecular mechanisms of the biological clock in health and diseases
      • Overview of the research

        Dr. Hitoshi Okamura is a Professor of Department of Systems Biology in Kyoto University Graduate School of Pharmaceutical Sciences. He received BA, MD and PhD in Kyoto Prfectural University of Medicine. Before the present status, he was the Professor of Brain Sciences in Kobe University Graduate School of Medicine between 1995-2008. Dr. Okamura begins his circadian study from 1982 by the peptide work in the suprachiasmatic nucleus (SCN) using the technique of histochemistry. He established quantitative histochemistry in 80’s, and in vitro slice culture of SCN in early 90’s. In Kobe, Dr. Okamura had his own laboratory, and he and his team discovered a number of important molecular mechanisms in mammals including cloning clock genes, cell rhythm at single cell level, clock-regulation of cell cycle timing, and transduction of rhythm signals in the body. After moving to Kyoto in 2007, Dr. Okamura and his team widened their works not only in the basic molecular mechanisms of circadian clocks but also the translational research linking molecular clock and life-style related diseases. They discovered that methylation of messenger RNA alters the period length of circadian rhythms, and also isolated a critical novel steroid synthetic enzyme in salt-induced hypertension from mice with dyregulated clock. They also found a molecular mechanism of jet-lag. Dr. Okamura received Medal with Purple Ribbon from Emperor of Japan for his contribution to the study on circadian rhythms.

      Research Interests

      • 時計遺伝子
      • 視交叉上核
      • サーカディアンリズム
      • 生体リズム
      • in situ hybridization
      • 転写因子
      • ノックアウトマウス
      • 体内時計
      • VIP
      • ピリオド遺伝子
      • ルシフェラーゼ
      • 細胞分裂
      • Per2
      • 副腎
      • Cry
      • 視床下部
      • 哺乳類時計遺伝子
      • 生物時計
      • リズム変異マウス

      Research Areas

      • Life sciences, Neuroanatomy and physiology
      • Life sciences, Neuroscience - general
      • Life sciences, Psychiatry
      • Life sciences, Biomaterials
      • Life sciences, Biomedical engineering
      • Life sciences, Pathobiochemistry
      • Life sciences, Cell biology

      Misc.

      • Central Circadian Clock and Energy Metabolism
        薛 元瑞; 土居 雅夫; 岡村 均
        内分泌・糖尿病・代謝内科 = Endocrinology, diabetology & metabolism, Jul. 2015

      Awards

      • Jul. 1999
        第13回塚原仲晃記念賞
      • Feb. 2001
        第17回井上学術賞
      • Nov. 2003
        日本医師会医学賞
      • Oct. 2004
        井植記念賞
      • Jun. 2007
        紫綬褒章
      • May 2009
        Aschoff-Ruler Prize

      External funds: Kakenhi

      • 昼行性霊長類を用いた生体リズ ム解析系の確立
        Grant-in-Aid for Challenging Research (Exploratory)
        Medium-sized Section 10:Psychology and related fields
        Osaka University
        冨永 恵子
        From 30 Jul. 2020, To 31 Mar. 2024, Granted
        概日リズム;マーモセット;昼行性霊長類;体内時計;脳波;ケモカイン
      • Circadian clock oscillation in primate SCN
        Grant-in-Aid for Scientific Research (A)
        Medium-sized Section 46:Neuroscience and related fields
        Kyoto University
        Hitoshi Okamura
        From 01 Apr. 2018, To 31 Mar. 2021, Project Closed
        概日リズム;時計遺伝子;視交叉上核;時差;シグナル伝達;ケモカイン;自然免疫;霊長類;生体リズム;リズム発振;リズム同調;哺乳類;神経科学;生体分子;脳・神経;シスエレメント;ノンコーディングDNA;細胞・組織;遺伝子;脳神経機構
      • Circadian regulation of sex steroids in aged skin after menopause
        Grant-in-Aid for Challenging Exploratory Research
        Kyoto University
        Doi Masao
        From 01 Apr. 2015, To 31 Mar. 2016, Project Closed
        概日時計;皮膚;性ステロイド;ステロイド合成律速酵素
      • Development of mice model of breast cancer with abnormal clock
        Grant-in-Aid for Challenging Exploratory Research
        Kyoto University
        Hitoshi Okamura
        From 01 Apr. 2015, To 31 Mar. 2016, Project Closed
        時計遺伝子;乳癌;トランスクリプトーム;免疫;マウス
      • Circadian clock oscillation in the SCN
        Grant-in-Aid for Scientific Research (A)
        Kyoto University
        HITOSHI OKAMURA
        From 01 Apr. 2015, To 31 Mar. 2018, Project Closed
        概日リズム;時計遺伝子;シグナル伝達;視交叉上核;Gタンパク質;細胞周期;時差;昼寝;生体リズム;RNAメチル化;カゼインキナーゼ;遺伝子;GPCR;脳・神経;生体分子;神経科学;細胞・組織;神経回路;生理学;時間生物学;光ファイバー;ルシフェラーゼ
      • Development of plasma steroid precursor-based new differential diagnosis and molecular targeted therapies for hyperaldosteronism
        Grant-in-Aid for Challenging Exploratory Research
        Kyoto University
        Doi MASAO
        From 01 Apr. 2014, To 31 Mar. 2015, Project Closed
        アルドステロン;副腎;ステロイド合成酵素
      • Epigenetics of developmental abnormality of biological rhythms
        Grant-in-Aid for Challenging Exploratory Research
        Kyoto University
        Hitoshi OKAMURA
        From 01 Apr. 2014, To 31 Mar. 2015, Project Closed
        生物リズム・エピジェネティックス;生体リズム;エピジェネティックス
      • Elucidating the mechanisms of kidney fibrosis and regeneration
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        Motoko Yanagita
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        線維化;再生;炎症;老化;内科;再生医学;循環器;急性腎障害;慢性腎臓病;腎性貧血
      • Identification and characterization of a potential drug target regulating the pace of the central circadian clock in the brain
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        Masao Doi
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        G蛋白質共役型受容体;体内時計;オーファン受容体;視交叉上核;G蛋白質共役受容体;概日時計;GPCR
      • Alternation of organ function in mice of jet-lag model
        Grant-in-Aid for Challenging Exploratory Research
        Kyoto University
        Hitoshi OKAMURA
        From 01 Apr. 2013, To 31 Mar. 2014, Project Closed
        脳とリズム;時差;生活習慣病;シフトワーク;視交叉上核;体重増加
      • ステロイド合成細胞のクロノメタボリズム:細胞代謝と生理の概日時計による制御機構
        Grant-in-Aid for JSPS Fellows
        Kyoto University
        岡村 均
        From 01 Apr. 2013, To 31 Mar. 2016, Project Closed
        circadian;ステロイド;アルドステロン;脂肪;生体リズム;転写制御;時計遺伝子
      • Detection of circadian rhythms from peripheral blood samples in the diagnosis of diseases of elderly people
        Grant-in-Aid for Challenging Exploratory Research
        Kyoto University
        Hitoshi OKAMURA
        From 01 Apr. 2012, To 31 Mar. 2013, Project Closed
        遺伝子;循環器・高血圧;トランスレーションリサーチ;バイオテクノロジー
      • SCN-Gene-Project: Molecular analysis of biological rhythms
        Grant-in-Aid for Scientific Research (A)
        Kyoto University
        Hitoshi OKAMURA
        From 01 Apr. 2012, To 31 Mar. 2015, Project Closed
        時計遺伝子・視交叉上核・時差;生体リズム;時差;バソプレッシン;受容体;視交叉上核;DNAマイクロアレイ;ノックアウトマウス;ペプチド;シグナル伝達;生理学;脳・神経
      • 時差症候群の分子機構の解明とその治療に関する研究
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Kyoto University
        岡村 均
        From 01 Apr. 2012, To 31 Mar. 2014, Project Closed
        生体リズム;時差;時計遺伝子;バソプレッシン;視交叉上核;受容体;拮抗剤;遺伝子;行動学;生理学;トランスレーショナルリサーチ;脳・神経
      • Histone demethylase Jmjd1a as a regulator of glycolipid metabolism
        Grant-in-Aid for Young Scientists (A)
        The University of Tokyo
        Takeshi INAGAKI
        From 01 Apr. 2009, To 31 Mar. 2013, Project Closed
        エピゲノム;ヒストン脱メチル化酵素;Jmjd1a;糖脂質代謝調節;ヒストン;Jmjdla;肥満;ChIPシークエンス;RNAシークエンス;ヒストンメチル化;エビゲノム;H3K9;Jhdm2a;代謝;糖脂質代謝;ChIP
      • Investigation on molecular biological mechanism of diurnal micturition rhythm
        Grant-in-Aid for Scientific Research (B)
        Hyogo Medical University;Kyoto University
        Akihiro KANEMATSU
        From 01 Apr. 2009, To 31 Mar. 2012, Project Closed
        時計遺伝子;コネキシン43;ギャップジャンクション;Rev-erbalpha;Sp-1;日内排尿リズム;PTH-rP;排尿発達
      • Molecular Clocks to Biological Rhythms
        Grant-in-Aid for Specially Promoted Research
        Biological Sciences
        Kyoto University;Kobe University
        Hitoshi OKAMURA
        From 01 Apr. 2006, To 31 Mar. 2011, Project Closed
        時計遺伝子;視交叉上核;G蛋白質;臓器の時計;高血圧;神経科学;発現制御;生理学;脳科学;遺伝子;発光;皮膚;生体リズム;サーカディアンリズム;GPCR;振動子;ペプチド;腎尿細管;ヒートショックプロテイン;喘息;Flightless;Per2
      • 睡眠時の副腎皮質ホルモン分泌の時計遺伝子によるサーカディアン制御機構
        Grant-in-Aid for Scientific Research (C)
        Kobe University
        上山 友子
        From 01 Apr. 2005, To 31 Mar. 2008, Project Closed
        生体リズム;発現制御;生理学;脳・神経;時計遺伝子
      • Study on the imaging technique of fluorescent marker and reporter to extract biological function and gene expression base on the ultrasound tagging fluorescence detection method
        Grant-in-Aid for Scientific Research (C)
        Tohoku Institute of Technology
        Masaki KOBAYASHI
        From 01 Apr. 2005, To 31 Mar. 2007, Project Closed
        生体;蛍光;超音波;音響光学効果;遺伝子発現;レポータ遺伝子;可視化;イメージング, biomedical imaging;fluorescence;ultrasound;acousto-optic;gene expression;reporter gene;visualization;imaging
      • 細胞から個体までのリズム遺伝子発現の統合システムの解析
        Grant-in-Aid for Scientific Research (A)
        Kobe University
        岡村 均
        From 01 Apr. 2005, To 31 Mar. 2007, Project Closed
        時計遺伝子;Per2;コア・ループ;視交叉上核;副腎皮質ホルモン;転写
      • 脳における時間シグナルの構築
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Kobe University
        岡村 均
        From 01 Apr. 2005, To 31 Mar. 2006, Project Closed
        視交叉上核;副腎;時計遺伝子;時計蛋白結合;マウス
      • 細胞時計による生死決定とがん化の研究
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Kobe University
        岡村 均
        From 01 Apr. 2005, To 31 Mar. 2006, Project Closed
        発癌剤;アポトーシス;副腎;肝臓;マウス
      • Clarification of molecular mechanism of Jet Lag
        Grant-in-Aid for Scientific Research (C)
        Kobe University
        Satoru MASUBUCHI
        From 01 Apr. 2004, To 31 Mar. 2006, Project Closed
        時差症候群;時計遺伝子, Jet lag syndrome;Clock genes
      • 発がん時の細胞時計の研究
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Kobe University
        岡村 均
        From 01 Apr. 2004, To 31 Mar. 2005, Project Closed
        時計遺伝子;ユビキチン・プロテアゾーム;細胞分裂;Per2;Per1
      • 時計遺伝子による皮膚の日内リズムの解明
        Grant-in-Aid for Exploratory Research
        Kobe University
        岡村 均
        From 01 Apr. 2003, To 31 Mar. 2005, Project Closed
        時計遺伝子;皮膚;細胞分裂;ケラチノサイト;末梢臓器;生体リズム;per2;免疫組織化学;ノーザンブロット
      • 体内時計の分子・生理機構
        Grant-in-Aid for Scientific Research (C)
        Waseda University
        柴田 重信
        From 01 Apr. 2003, To 31 Mar. 2004, Project Closed
        体内時計;時計遺伝子;分子機構;リズム障害;分子生理;環境生理;生体リズム;細胞内・細胞間情報伝達
      • Signal transduction of clock genes in molecular clock
        Grant-in-Aid for Scientific Research (A)
        Kobe University
        Hitoshi OKAMURA
        From 01 Apr. 2003, To 31 Mar. 2005, Project Closed
        時計遺伝子;mPer遺伝子群;Hes;末梢時計;コルチコステロン;副腎;生体リズム;松果体;視交叉上核;細胞分裂;細胞周期;シングルセルリズム;遺伝子発現, clock genes;suprachiasmatic nucleus;liver;mPer;Hes;clock signals;cell cycle
      • 時計遺伝子を利用したリズム障害調整剤の開発
        Grant-in-Aid for Exploratory Research
        Kobe University
        岡村 均
        From 01 Apr. 2001, To 31 Mar. 2002, Project Closed
        時計遺伝子;エンドセリン;トランスジェニックマウス;視交叉上核;サーカディアンリズム;ペプチド;アミン
      • 生物時計の動きの機構の解明
        Grant-in-Aid for Scientific Research (S)
        Kobe University
        岡村 均
        From 01 Apr. 2001, To 31 Mar. 2004, Project Closed
        時計遺伝子;サーカディアンリズム;転写因子;遺伝子改変マウス;生物時計;中枢;核内移行;リズム変異マウス
      • 哺乳類生体リズムの分子制御機構の解明
        Grant-in-Aid for Scientific Research (A)
        Kobe University
        岡村 均
        From 01 Apr. 2001, To 31 Mar. 2002, Project Closed
      • GAL4-UASを用いた時計遺伝子過剰発現システム
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Kobe University
        山口 瞬
        From 01 Apr. 2001, To 31 Mar. 2003, Project Closed
        時計遺伝子;体内時計;概日リズム;トランスジェニックマウス
      • 生物時計遺伝子によるリズム発振分子機構の解析
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Kobe University
        岡村 均
        From 01 Apr. 2001, To 31 Mar. 2003, Project Closed
        CRY;時計遺伝子;サーカディアンリズム;転写因子;遺伝子改変マウス;ショウジョウバエ;mPer1プロモーター;トランスジェニックマウス;ルシフェラーゼ;概日リズム;cry遺伝子;dbp;Cry;ノックアウトマウス;フォルスコリン;単一細胞のリズム;mPer1ゲノム
      • トランスジェニックショウジョウバエを用いた哺乳類時計遺伝子の機能解析
        Grant-in-Aid for Exploratory Research
        Kobe University
        岡村 均
        From 01 Apr. 2000, To 31 Mar. 2001, Project Closed
        ショウジョウバエ;時計遺伝子;period遺伝子;無周期ミュータント;timeless;遺伝子導入
      • 哺乳類GAL4/UASシステムの開発による時計遺伝子発振システムの解明
        Grant-in-Aid for Scientific Research (B)
        Kobe University
        岡村 均
        From 01 Apr. 2000, To 31 Mar. 2003, Project Closed
        GAL4-UAS;mPer1プロモーター;時計遺伝子;トランスジェニックマウス
      • GAL4-UASシステムを用いた時計遺伝子の解析
        Grant-in-Aid for Scientific Research on Priority Areas (A)
        Biological Sciences
        Kobe University
        山口 瞬
        From 01 Apr. 2000, To 31 Mar. 2001, Project Closed
        体内時計;時計遺伝子;プロモーター;視交叉上核;行動リズム
      • 人工生物時計(バイオクロック)の開発
        Grant-in-Aid for Exploratory Research
        Kobe University
        岡村 均
        From 01 Apr. 1999, To 31 Mar. 2000, Project Closed
        生物時計;哺乳類時計遺伝子;サーカディアンリズム;rat-1;Cos7;遺伝子導入;培養細胞
      • Molecular basis of circadian rhythms : function of clock genes
        Grant-in-Aid for Scientific Research (A).
        Nagoya University
        Takao KONDO
        From 01 Apr. 1999, To 31 Mar. 2001, Project Closed
        シアノバクテリア;マウス;概日時計;時計遺伝子;ショウジョウバエ;蛋白質相互作用;視交叉上核;時計蛋白のリン酸化, cyanobacteria;mouse;circadian clock;clock genes;Drosophila;protein interaction;suprachiasmatic nuclei;phosphorylation
      • Molecular mechanism of mammalian biological rhythms
        Grant-in-Aid for Scientific Research (C)
        Kobe University
        Toru TAKUMI
        From 01 Apr. 1999, To 31 Mar. 2001, Project Closed
        概日リズム;時計遺伝子;視交叉上核;視交又上核;period;timeless, Circadian rhythm;clock gene;suprachiasmatic nucleus
      • Molecular Biology of the Biological Clock : From Gene to Behavior
        Grant-in-Aid for Scientific Research (B).
        Kobe University
        Hitoshi OKAMURA
        From 01 Apr. 1999, To 31 Mar. 2001, Project Closed
        ノックアウトマウス;cry;時計遺伝子;mPer1プロモーター;E-box;トランスジェニックマウス;ルシフェラーゼ;概日リズム;哺乳類時計遺伝子;サーカディアンリズム;Cry;単一細胞のリズム, mPer1;clock genes;dbp;cry;e4bp4;circadian rhythm;transgenic mice;suprachiasmatic nucleus
      • 生体時計の分子機構
        Grant-in-Aid for Scientific Research on Priority Areas
        Biological Sciences
        Waseda University;Kobe University
        柴田 重信;岡村 均
        From 01 Apr. 1999, To 31 Mar. 2003, Project Closed
        時計遺伝子;体内時計;サーカディアンリズム;機能分子;睡眠リズム障害;睡眠相後退症候群;季節性感情障害患者;転写因子;リズム変異マウス;遺伝子改変マウス;生物時計;早期発現遺伝子;トランスジェニックマウス;視交叉上核;概日リズム;メラトニン;マルチ電極ディッシュ;Cry;ノックアウトマウス;リズムの消失;アンチセンス
      • 哺乳類時計遺伝子mPer1,mPer2,mPer3の転写調節機構
        Grant-in-Aid for Scientific Research on Priority Areas (A)
        Kobe University
        岡村 均
        From 01 Apr. 1999, To 31 Mar. 2000, Project Closed
        mPer1;mPer2;哺乳類時計遺伝子;mPer1プロモーター;サーカディアンリズム;遺伝子導入
      • 光による時計蛋白TIMELESSの分解機構の解明
        Grant-in-Aid for Scientific Research on Priority Areas (A)
        Kobe University
        内匠 透
        From 01 Apr. 1999, To 31 Mar. 2000, Project Closed
        概日リズム;時計蛋白;視交又上核;蛋白分解;TIMELESS
      • 抗がん剤の薬物動態と投薬のタイミングの基盤となる生体リズムの制御機構
        Grant-in-Aid for Scientific Research on Priority Areas (A)
        Kobe University
        内匠 透
        From 01 Apr. 1999, To 31 Mar. 2000, Project Closed
        概日リズム;時計遺伝子;視交又上核;薬物動態
      • サーカディアンリズム形成に伴う時計遺伝子の発現とその制御機構
        Grant-in-Aid for Scientific Research on Priority Areas (A)
        Kobe University
        岡村 均
        From 01 Apr. 1998, To 31 Mar. 1999, Project Closed
        転写因子;DNA結合ドメイン;クローニング;視交叉上核;時計遺伝子;発生;サーカディアンリズム
      • 時計遺伝子のリズム位相制御機構
        Grant-in-Aid for Scientific Research on Priority Areas (A)
        Kobe University
        岡村 均
        From 01 Apr. 1998, To 31 Mar. 1999, Project Closed
        視交叉上核;時計遺伝子;ピリオド遺伝子;核移行;サーカディアンリズム;タイムレス遺伝子;位相変位;クローニング
      • Study of DNA repair deficient mice
        Grant-in-Aid for Scientific Research (B)
        Tohoku University
        Akira YASUI
        From 01 Apr. 1998, To 31 Mar. 2001, Project Closed
        DNA修復;ジーンターゲッティング;修復欠損マウス;日周リズム;光回復;光回復酵素;サーカディアンリズム;ノックアウトマウス;活性酸素;老化;ジーンターゲーティング;青色光受容体, DNA repair;gene targeting;repair deficient mouse;circadian rhythm;photo repair
      • 松果体メラトニンリズムの神経栄養因子による制御機構
        Grant-in-Aid for Scientific Research (C)
        Kobe University
        藤本 悦子
        From 01 Apr. 1997, To 31 Mar. 1999, Project Closed
        メラトニン;松果体;超微細構造
      • Molecular analysis of the mammalian circulation rhythm
        Grant-in-Aid for Scientific Research (B)
        Kobe University
        Hitoshi OKAMURA
        From 01 Apr. 1997, To 31 Mar. 1999, Project Closed
        視交叉上核;時計遺伝子;ピリオド遺伝子;タイムレス遺伝子;位相変位;クローニング;明暗条件;サーカディアンリズム;哺乳類period遺伝子;内因性リズム;光誘導, clock genes;circadian rhythms;mPer1;mPer2;mPer3;mTim;suprachiasmatic nucleus;mammals
      • 概日リズムの形成及び同調に伴う遺伝子発現とその制御機構
        Grant-in-Aid for Scientific Research on Priority Areas
        Kobe University
        岡村 均
        From 01 Apr. 1997, To 31 Mar. 1998, Project Closed
        哺乳類period遺伝子;時間特異的発現遺伝子;光誘発遺伝子;リズム発現
      • Effects of aging to circadian entrainment
        Grant-in-Aid for Scientific Research (C)
        Kyoto Prefectural University of Medicine
        Fumio KAWAKAMI
        From 01 Apr. 1996, To 31 Mar. 1998, Project Closed
        Vasoactive intestinal peptide;Suprachiasmatic nucleus;in situ hybridization;Aging;Rat, Vasoactive intestinal peptide;Suprachiasmatic nucleus;In situ hybridization;Aging
      • Real time monitoring of mammalian circadian rhythm by bio-sensor
        Grant-in-Aid for Scientific Research (A)
        Kobe University
        Hitoshi OKAMURA
        From 01 Apr. 1996, To 31 Mar. 1999, Project Closed
        水晶振動子センサー;免疫センサー;共振周波数;細胞培養;ルシフェラーゼ;時計遺伝子;サーカディアンリズム;フォトン検出装置;Rat1;視交叉上核;ピリオド遺伝子;概日リズム, clock genes;luciferase-;mPer1-promotor;bioaffinity binding
      • 光による生体内情報リズムの制御機構
        Grant-in-Aid for Scientific Research (A)
        Kyoto Prefectural University of Medicine
        井端 泰彦
        From 01 Apr. 1996, To 31 Mar. 1998, Project Closed
        概日リズム;視交叉上核;遺伝子;内分泌;行動;自律神経;ゲッ歯類;ヒト
      • 概日リズムの位相変位関連遺伝子の視交叉上核における発現
        Grant-in-Aid for Scientific Research on Priority Areas
        Kobe University
        岡村 均
        From 01 Apr. 1996, To 31 Mar. 1998, Project Closed
        Differential mRNA display法;VIP;時間特異的発現遺伝子;光誘発関連遺伝子;リズム発現
      • Serotonergic regulation to the suprachiasmatic nuleus
        Grant-in-Aid for General Scientific Research (C)
        Kyoto Prefectural University of Medicine
        Fumio KAWAKAMI
        From 01 Apr. 1994, To 31 Mar. 1996, Project Closed
        セロトニン;視交叉上核;生体リズム;In situ hybridazation, Suprachiasmatic nucleus;Vasoactive intestinal peptide;Serotonin;In situ hybridization
      • Hypothalamic hormones and central neuronal regulation following
        Grant-in-Aid for General Scientific Research (C)
        Kyoto Prefectural University of Medicine
        Hitoshi OKAMURA
        From 01 Apr. 1993, To 31 Mar. 1995, Project Closed
        侵害刺激;VGF;バソプレッシン;エンケファリン;in situhybridization;水浸拘束ストレス;高張食塩水負荷;視床下部ペプチド;後根神経節;視床下部;神経ペプチド;c-fos;in situ hybridization, nociception;hyperosmotic stress;vasopressin;dynorphin;galanin;VGF;immunocytochemistry;in situ hybridization
      • 6-OHDA及びMPPのよる黒質線条体系ドーパミン神経細胞死とフリーラジカル
        Grant-in-Aid for Scientific Research on Priority Areas
        Kyoto Prefectural University of Medicine
        井端 泰彦
        From 01 Apr. 1993, To 31 Mar. 1994, Project Closed
        6-CHDA;ドーパミン;NCS;プロテインカイネースC;免疫細胞化学;生化学;線条体;黒質
      • Functional morphology of suprachiasmatic nucleus
        Grant-in-Aid for General Scientific Research (B)
        Kyoto Prefectural University of Medicine
        Yasuhiko IBATA
        From 01 Apr. 1992, To 31 Mar. 1994, Project Closed
        視交叉上核;VIP;バソプレシン;AADC;免疫細胞化学;インサイツハイブリデーション;網膜;霊長類;視神経;二重標識電顕免疫細胞化学;ニホンザル;ラット, Suprachiasmatic nucleus;VIP;Vasopressin;AADC;immunocytochemistry;in situ hybidization;retina;primate
      • Functional Morphology of A PUD neurons in the central nervous system
        Grant-in-Aid for General Scientific Research (C)
        Kyoto prefectural University of Medicine
        Hitoshi OKAMURA
        From 01 Apr. 1991, To 31 Mar. 1993, Project Closed
        Amine Precursor uptake and decarboxylation;L-DOPA;Aromatic L-amino acid decarboxylase;ドーパミン;^3H-DOPA;視床下部;aromaticL-aminoacid decarboxylase;in situ hybridization;オートラジオグラフィー;aromatic Lーamino acid decarboxyla;tyrosine hydroxylase;ド-パミン;amine precursor uptake and de, Amine Precursor uptake and decarboxylation;L-DOPA;Aromatic L-amino acid decarboxylase;dopamine;^3H-DOPA;Hypothalamus;Brain
      • Morphological Survey of L-DOPA Containing Neurons in the Central Nervous System.
        Grant-in-Aid for General Scientific Research (C)
        Kyoto Prefectural University of Medicine
        Hitoshi OKAMURA
        From 01 Apr. 1989, To 31 Mar. 1991, Project Closed
        ド-パミン;ド-パ;免疫組織化学, L-DOPA;Dopamine;Immunocytochemistry;Tyrosine Hydroxylase;Aromatic L-amino acid decarboxylase.
      • Functional Morphology of the Suprachiasmatic Nucleus with Special Reference to its Role as the Circadian Oscillator Under Influence of Retinal Input.
        Grant-in-Aid for General Scientific Research (B)
        Kyoto Prefectural University of Medicine
        Yasuhiko IBATA
        From 01 Apr. 1989, To 31 Mar. 1991, Project Closed
        視交叉上核;VIP;バワプレシン;日内変動;免疫細胞化学;mRNA;in situ hybridization;光刺激;バソプレシン;上丘;網膜;線維投射;霊長類;画像解析;視神経入力;ラット, suprachiasmatic nucleus;VIP;vasopressin;mRNA;immunocytochemistry;in sity hybridization;retina;primate
      • Research on functional morphology of hypothalamic paraventricular and suprachiasmatic nuclei.
        Grant-in-Aid for General Scientific Research (B)
        Kyoto Prefectural University of Medicine
        Yasuhiko. IBATA
        From 01 Apr. 1985, To 31 Mar. 1988, Project Closed
        ペプチド;室傍核;視交叉上核;弓状核;微細構造;線維入力;免疫細胞化学;視床下部;VIP;PHI;バソプレシン;NPY;光顕免疫組織化学;電顕免疫組織化学, Peptides;Parayentricular nucleus;Suprachiasmatic nucleus;Arcuate nucleus;Fine structure;Neuronal input
      • Research on the biological rhythm oscillation by full-spectrum solar LED
        Grant-in-Aid for Challenging Research (Pioneering)
        Medium-sized Section 51:Brain sciences and related fields
        Kyoto University
        岡村 均
        From 30 Jun. 2022, To 31 Mar. 2025, Granted
        生体リズム;LED;光;リズム中枢;霊長類;齧歯類
      • Primate neurobiological mechanisms underlying sleep-wake abnormality
        Grant-in-Aid for Scientific Research (B)
        Basic Section 51030:Pathophysiologic neuroscience-related
        Kyoto University
        岡村 均
        From 01 Apr. 2023, To 31 Mar. 2026, Granted
        生体リズム;睡眠覚醒リズム;霊長類;時差;睡眠障害
      • Primate neurobiological mechanisms underlying sleep-wake abnormality
        Grant-in-Aid for Scientific Research (B)
        Basic Section 51030:Pathophysiologic neuroscience-related
        Kyoto University
        岡村 均
        From 01 Apr. 2023, To 31 Mar. 2026, Granted
        生体リズム;睡眠覚醒リズム;霊長類;時差;睡眠障害

      External funds: others

      • ゲノム解析による原発性アルドステロン症の原因診断学の再構築
        厚生労働科学研究費
        From 01 Apr. 2010, To 31 Mar. 2013
        岡村均
      list
        Last Updated :2025/05/02

        Education

        Teaching subject(s)

        • From Apr. 2011, To Mar. 2012
          一般生理学
          Fall, 薬学部
        • From Apr. 2011, To Mar. 2012
          特別実習(システムバイオロジー)
          Year-long, 薬学部
        • From Apr. 2011, To Mar. 2012
          生理学1(解剖生理学)
          Fall, 薬学部
        • From Apr. 2011, To Mar. 2012
          特別実習[システムバイオロジー]
          Year-long, 薬学部
        • From Apr. 2011, To Mar. 2012
          Introduction to Modern Life Sciences
          Spring, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Skill Development for
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Skill Development for
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Bioinformatics II: Lead Discovery
          Spring, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Advanced Methods in Systems
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Advanced Methods in Systems
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Research in Systems
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Research in Systems
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          生理学4(病態ゲノム学)
          Spring, 薬学部
        • From Apr. 2011, To Mar. 2012
          生理学3(病態生理学)
          Fall, 薬学部
        • From Apr. 2011, To Mar. 2012
          病態生理学
          Fall, 薬学部
        • From Apr. 2011, To Mar. 2012
          An Introduction to Pharmaceutical Sciences and Ethics
          Spring, 全学共通科目
        • From Apr. 2012, To Mar. 2013
          General Physiology
          Fall, 薬学部
        • From Apr. 2012, To Mar. 2013
          Bioinformatics II: Lead Discovery
          Spring, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          doctoral program
          Spring, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          doctoral program
          Fall, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2012, To Mar. 2013
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2012, To Mar. 2013
          Introduction to Modern Life Sciences
          Spring, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Research in Systems Biology & Drug Dicovery
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Physiology 4 (Genomic medicine)
          Spring, 薬学部
        • From Apr. 2012, To Mar. 2013
          Physiology 3 (Pathophysiology for drug discovery and personalized medicine)
          Fall, 薬学部
        • From Apr. 2012, To Mar. 2013
          Physiology 1 (Anatomical Physiology)
          Fall, 薬学部
        • From Apr. 2012, To Mar. 2013
          Pathogenesis of major symptoms and signs
          Fall, 薬学部
        • From Apr. 2012, To Mar. 2013
          Skill Development for Clinical Researches
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          An Introduction to Pharmaceutical Sciences and Ethics
          Spring, 全学共通科目
        • From Apr. 2013, To Mar. 2014
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2013, To Mar. 2014
          Physiology 1 (Anatomical Physiology)
          Fall, 薬学部
        • From Apr. 2013, To Mar. 2014
          Physiology 3 (Pathophysiology for drug discovery and personalized medicine)
          Fall, 薬学部
        • From Apr. 2013, To Mar. 2014
          Physiology 4 (Genomic medicine)
          Spring, 薬学部
        • From Apr. 2013, To Mar. 2014
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2013, To Mar. 2014
          Introduction to Modern Life Sciences
          Spring, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Skill Development for Clinical Researches
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Research in Systems Biology & Drug Dicovery
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          doctoral program
          Spring, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          doctoral program
          Fall, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          An Introduction to Pharmaceutical Sciences and Ethics
          Spring, 全学共通科目
        • From Apr. 2014, To Mar. 2015
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2014, To Mar. 2015
          Physiology 1 (Anatomical Physiology)
          Fall, 薬学部
        • From Apr. 2014, To Mar. 2015
          Physiology 3 (Pathophysiology for drug discovery and personalized medicine)
          Fall, 薬学部
        • From Apr. 2014, To Mar. 2015
          Physiology 4 (Genomic medicine)
          Spring, 薬学部
        • From Apr. 2014, To Mar. 2015
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2014, To Mar. 2015
          Introduction to Modern Life Sciences
          Spring, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Bioinformatics II: Lead Discovery
          Spring, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Skill Development for Clinical Researches
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Research in Systems Biology & Drug Dicovery
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          An Introduction to Pharmaceutical Sciences and Ethics
          Spring, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Global Frontier in Life Science A
          Spring, 生命科学研究科
        • From Apr. 2015, To Mar. 2016
          Introduction to Information Sciences
          Spring, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2015, To Mar. 2016
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2015, To Mar. 2016
          Introduction to Modern Life Sciences
          Spring, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Frontiers of Biology
          Spring, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Research in Systems Biology & Drug Dicovery
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Physiology 4 (Genomic medicine)
          Spring, 薬学部
        • From Apr. 2015, To Mar. 2016
          Physiology 3 (Pathophysiology for drug discovery and personalized medicine)
          Fall, 薬学部
        • From Apr. 2015, To Mar. 2016
          Physiology 1 (Anatomical Physiology)
          Fall, 薬学部
        • From Apr. 2015, To Mar. 2016
          Skill Development for Clinical Researches
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          An Introduction to Pharmaceutical Sciences and Ethics
          Spring, 全学共通科目
        • From Apr. 2016, To Mar. 2017
          Bioinformatics II: Lead Discovery
          Spring, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Introduction to Information Sciences
          Spring, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2016, To Mar. 2017
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2016, To Mar. 2017
          Introduction to Modern Life Sciences
          Spring, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Frontiers of Biology
          Spring, 全学共通科目
        • From Apr. 2016, To Mar. 2017
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Research in Systems Biology & Drug Dicovery
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Physiology 4 (Genomic medicine)
          Spring, 薬学部
        • From Apr. 2016, To Mar. 2017
          Physiology 3 (Pathophysiology for drug discovery and personalized medicine)
          Fall, 薬学部
        • From Apr. 2016, To Mar. 2017
          Physiology 1 (Anatomical Physiology)
          Fall, 薬学部
        • From Apr. 2016, To Mar. 2017
          Skill Development for Clinical Researches
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Introduction to Pharmaceutical Sciences and Ethics
          Spring, 全学共通科目
        • From Apr. 2017, To Mar. 2018
          Introduction to Modern Life Sciences for Drug Discovery
          Spring, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Advanced Basic Biological Chemistry I
          Spring, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Introduction to Information Sciences
          Spring, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2017, To Mar. 2018
          Research Training(Systems Biology)
          Year-long, 薬学部
        • From Apr. 2017, To Mar. 2018
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Advanced Methods in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Research in Systems Biology & Drug Dicovery
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Research in Systems Biology & Drug Discovery
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Physiology 4 (Genomic medicine)
          Spring, 薬学部
        • From Apr. 2017, To Mar. 2018
          Physiology 3 (Pathophysiology for drug discovery and personalized medicine)
          Fall, 薬学部
        • From Apr. 2017, To Mar. 2018
          Physiology 1 (Anatomical Physiology)
          Fall, 薬学部
        • From Apr. 2017, To Mar. 2018
          Skill Development for Clinical Researches
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Introduction to Clinical Pharmacy
          Spring, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Introduction to Pharmaceutical Sciences and Ethics
          Spring, 全学共通科目
        list
          Last Updated :2025/05/02

          Administration

          School management (title, position)

          • From 01 Apr. 2010, To 31 Mar. 2011
            国際教育プログラム委員会 委員
          • From 01 Apr. 2009, To 31 Mar. 2011
            FD研究検討委員会 委員
          • From 01 Apr. 2011, To 31 Mar. 2012
            国際教育プログラム委員会 委員

          Faculty management (title, position)

          • From 01 Apr. 2015, To 31 Mar. 2019
            薬学研究科医薬創成情報科学専攻長
          • From 01 Apr. 2011, To 31 Mar. 2012
            情報システム委員会 委員
          • From 01 Apr. 2013, To 31 Mar. 2014
            入試等問題検討委員会 委員
          • From 01 Apr. 2015, To 31 Mar. 2016
            入試等問題検討委員会 委員長
          • From 01 Apr. 2015
            将来計画委員会 委員
          • From 01 Apr. 2015
            予算委員会 委員
          • From 01 Apr. 2015
            自己評価等調査検討委員会 委員
          • From 01 Apr. 2015
            薬用植物園管理委員会 委員
          • From 01 Apr. 2015
            エネルギー管理委員会 委員
          • From 01 Apr. 2015
            国際交流委員会 委員
          • From 01 Apr. 2015
            寄附講座検討委員会 委員
          • From 01 Apr. 2011, To 30 Sep. 2012
            教務委員会 委員

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