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Yamashita, Kouhei

Graduate School of Medicine, Medicine Associate Professor

Yamashita, Kouhei
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    Last Updated :2025/04/23

    Basic Information

    Faculty

    • 医学部

    Academic Degree

    • 博士（医学）(京都大学)

    Academic Resume (Graduate Schools)

    • 京都大学, 大学院医学研究科博士課程, 修了

    Academic Resume (Undergraduate School/Majors)

    • 京都大学, 医学部医学科, 卒業

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    researchmap URL

    list
      Last Updated :2025/04/23

      Research

      Research Topics, Overview of the research

      • Research Topics

        1. The function of neutrophils
        2. The pathophysiology of the complications of allogeneic hematopoietic stem cell transplantation, such as GVHD and thrombotic microangiopathy.
        3. The role of sphingolipids on immune tolerance.

      • Overview of the research

        We investigate the function of neutrophils, especially focusing on neutrophil extracellular traps (NETs), known a novel extracelluar killing mechanism of neutrophils. We also examine the role of neutrophils in the pathogenesis of the complications of allogeneic stem cell transplantation, such as GVHD and microangiopathy. Furthermore, we are studying the role of sphingolipids on immune tolerance, such a maintaining pregnancy.

      Research Areas

      • Life sciences, Hematology and oncology

      Papers

      • 新菌種非結核性抗酸菌Mycobacterium kyorinenseによる縦隔リンパ節炎を発症した骨髄異形成症候群の1例
        西澤 正俊; 菱澤 方勝; 大楠 清文; 山下 浩平; 近藤 忠一; 樋口 武史; 飯沼 由嗣; 一山 智; 石川 隆之
        感染症学雑誌, Nov. 2010
      • 新菌種非結核性抗酸菌Mycobacterium kyorinenseによる縦隔リンパ節炎を発症した骨髄異形成症候群の一例
        西澤 正俊; 菱澤 方勝; 大楠 清文; 山下 浩平; 近藤 忠一; 樋口 武史; 飯沼 由嗣; 一山 智; 石川 隆之
        感染症学雑誌, Mar. 2010
      • Hearing loss occurs prior to thrombocytopenia in both mice and humans with DFNA1
        Shunkou Kurasawa; Akira Ganaha; Shinya Ayabe; Atsushi Yoshiki; Fumiya Kawama; Shota Kitayama; Keiji Tabuchi; Kouhei Yamashita; Takehiko Ueyama
        The FASEB Journal, 20 Jan. 2025
      • Increased relative eosinophil counts portend neck oedema after chimeric antigen receptor-T therapy.
        Naokazu Nakamura; Tomoyasu Jo; Yasuyuki Arai; Toshio Kitawaki; Momoko Nishikori; Chisaki Mizumoto; Junya Kanda; Kouhei Yamashita; Miki Nagao; Akifumi Takaori-Kondo
        British journal of haematology, 06 Jan. 2025
      • Severe cases of local cytokine release syndrome (CRS); craniocervical edema soon after chimeric antigen T-cell (CAR-T) therapy.
        Naokazu Nakamura; Tomoyasu Jo; Yasuyuki Arai; Toshio Kitawaki; Momoko Nishikori; Chisaki Mizumoto; Junya Kanda; Kouhei Yamashita; Miki Nagao; Akifumi Takaori-Kondo
        Oxford medical case reports, Jan. 2025
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      • Fluctuation of physical function during chimeric antigen receptor T-cell therapy during rehabilitation intervention: Real-world data and risk factor analyses.
        Ryota Hamada; Yasuyuki Arai; Toshio Kitawaki; Naokazu Nakamura; Masanobu Murao; Michiko Matsushita; Junsuke Miyasaka; Tsugumi Asano; Tomoyasu Jo; Momoko Nishikori; Junya Kanda; Chisaki Mizumoto; Kouhei Yamashita; Ryosuke Ikeguchi; Akifumi Takaori-Kondo
        EJHaem, Dec. 2024
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      • CAR-T細胞療法後に肺動脈内のT細胞塊を認めたtriple-hit DLBCLの1例
        中村 直和; 錦織 桃子; 水本 智咲; 阪本 貴士; 諫田 淳也; 白川 康太郎; 北脇 年雄; 近藤 忠一; 山下 浩平; 高折 晃史
        臨床血液, Aug. 2022
      • 嚥下障害を伴う治療関連急性骨髄性白血病に対してベネトクラクスを導入した1例
        中村 名欧; 和田 典也; 阪本 貴士; 諫田 淳也; 山際 岳朗; 米澤 淳; 寺田 智祐; 水本 智咲; 北脇 年雄; 近藤 忠一; 山下 浩平; 高折 晃史
        臨床血液, Feb. 2022
      • Early Diagnosis of Hereditary Angioedema in Japan Based on a US Medical Dataset: Algorithm Development and Validation.
        Kouhei Yamashita; Yuji Nomoto; Tomoya Hirose; Akira Yutani; Akira Okada; Nayu Watanabe; Ken Suzuki; Munenori Senzaki; Tomohiro Kuroda
        JMIR medical informatics, 13 Sep. 2024
      • [Concentration of gilteritinib in the cerebrospinal fluid of a patient with relapsed FLT3-ITD positive acute myeloid leukemia with optic nerve involvement].
        Yuta Suzuki; Toshio Kitawaki; Yasuyuki Arai; Shunsaku Nakagawa; Kazuhisa Chonabayashi; Yasuhito Nannya; Kouhei Yamashita; Seishi Ogawa; Akifumi Takaori-Kondo
        [Rinsho ketsueki] The Japanese journal of clinical hematology, 2024
      • Population Pharmacokinetic Modeling of Posaconazole in Japanese Patients Receiving Fungal Prophylaxis.
        Mitsuhiro Sugimoto; Atsushi Yonezawa; Junya Kanda; Kotaro Itohara; Daiki Hira; Takeo Yamagiwa; Risa Taniguchi; Yuta Hanyu; Mizuki Watanabe; Yasuyuki Arai; Chisaki Mizumoto; Toshio Kitawaki; Tadakazu Kondo; Kouhei Yamashita; Akifumi Takaori-Kondo; Tomohiro Terada
        Therapeutic drug monitoring, 04 Apr. 2024
      • 維持透析中の多発性骨髄腫患者に対する,キメラ抗原受容体T細胞(CAR-T)用リンパ球採取の経験
        河原 宏紀; 佐野 瞳; 城 友泰; 水本 智咲; 新井 康之; 諫田 淳也; 山下 浩平; 高折 晃史; 松原 雄; 柳田 素子
        日本輸血細胞治療学会誌, Feb. 2024
      • Utilizing red blood cell distribution width (RDW) as a reliable biomarker to predict treatment effects after chimeric antigen receptor T cell therapy
        Naokazu Nakamura; Tomoyasu Jo; Yasuyuki Arai; Toshio Kitawaki; Momoko Nishikori; Chisaki Mizumoto; Junya Kanda; Kouhei Yamashita; Miki Nagao; Akifumi Takaori-Kondo
        Clinical and Experimental Medicine, 21 May 2024
      • Bortezomib-cyclophosphamide-dexamethasone induction/consolidation and bortezomib maintenance for transplant-eligible newly diagnosed multiple myeloma: phase 2 multicenter trial
        Hiroyuki Muranushi; Junya Kanda; Masayuki Kobayashi; Takeshi Maeda; Toshiyuki Kitano; Masaaki Tsuji; Yasunori Ueda; Takayuki Ishikawa; Masaharu Nohgawa; Mitsumasa Watanabe; Kazunori Imada; Toshinori Moriguchi; Mitsuru Itoh; Hitoshi Ohno; Akihito Yonezawa; Hirokazu Hirata; Nobuyoshi Arima; Kohsuke Asagoe; Naoyuki Anzai; Kayoko Nagata; Shinji Yasuno; Yoshihiro Kuwabara; Hiromi Kitao; Ihhwa Kim; Kiyomi Kawagishi; Kenji Ueshima; Shinjiro Tominari; Takeo Nakayama; Kouhei Yamashita; Akifumi Takaori-Kondo
        Hematology, 13 Feb. 2022
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      • Maxillary sinus augmentation in a patient with hereditary angioedema with normal C1 inhibitor and familial Mediterranean fever
        Takuma Watanabe; Nodoka Mano; Kouhei Yamashita
        Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 2024
      • Clinical impact of CRS on prolonged hematotoxicity after CAR-T cell therapy: KyoTox a-score, a novel prediction model.
        Naokazu Nakamura; Tomoyasu Jo; Yasuyuki Arai; Toshio Kitawaki; Momoko Nishikori; Chisaki Mizumoto; Junya Kanda; Kouhei Yamashita; Miki Nagao; Akifumi Takaori-Kondo
        Transplantation and cellular therapy, 26 Jan. 2024
      • KyoTox-e score; prediction of post-CAR-T prolonged thrombocytopenia using peripheral blood data before apheresis
        Tomoyasu Jo; Yasuyuki Arai; Toshio Kitawaki; Naokazu Nakamura; Momoko Nishikori; Chisaki Mizumoto; Junya Kanda; Kouhei Yamashita; Miki Nagao; Akifumi Takaori-Kondo
        Bone Marrow Transplantation, 19 Dec. 2023
      • Risk analysis of fluctuating hypercalcemia after leukapheresis in cellular therapy
        Tomoyasu Jo; Yasuyuki Arai; Toshio Kitawaki; Momoko Nishikori; Chisaki Mizumoto; Junya Kanda; Kouhei Yamashita; Miki Nagao; Akifumi Takaori-Kondo
        Scientific Reports, 11 Sep. 2023
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      • Reciprocal regulation of protein arginine deiminase 2 and 4 expression in the colonic mucosa of ulcerative colitis
        Yasuo Otsuka; Yasuhiro Masuta; Kosuke Minaga; Natsuki Okai; Akane Hara; Ryutaro Takada; Sho Masaki; Ken Kamata; Hajime Honjo; Kouhei Yamashita; Masatoshi Kudo; Tomohiro Watanabe
        Journal of Clinical Biochemistry and Nutrition, 2023
      • Impact of Antimicrobial Drug-Drug Interactions on Acute Kidney Injury after Allogeneic Hematopoietic Cell Transplantation
        Fumiya Wada; Yasuyuki Arai; Tomoyasu Jo; Chisaki Mizumoto; Junya Kanda; Toshio Kitawaki; Momoko Nishikori; Kouhei Yamashita; Akifumi Takaori-Kondo
        Transplantation and Cellular Therapy, Jul. 2023
      • Epitope Mismatch at HLA-DRB1 Associates with Reduced Relapse Risk in Cord Blood Transplantation for Standard-Risk Hematologic Malignancy
        Mari Morita-Fujita; Takero Shindo; Tomoki Iemura; Yasuyuki Arai; Junya Kanda; Kazuya Okada; Yasunori Ueda; Onda Yoshiyuki; Naoyuki Anzai; Takuto Mori; Takayuki Ishikawa; Yasuyuki Otsuka; Akihito Yonezawa; Naoki Yuhi; Kazunori Imada; Akifumi Oba; Mitsuru Itoh; Yoshio Okamoto; Toshiyuki Kitano; Takashi Ikeda; Shinichi Kotani; Takashi Akasaka; Kazuhiro Yago; Mitsumasa Watanabe; Masaharu Nohgawa; Masaaki Tsuji; Tomoharu Takeoka; Ryusuke Yamamoto; Nobuyoshi Arima; Noriyoshi Yoshinaga; Masakatsu Hishizawa; Kouhei Yamashita; Tadakazu Kondo; Akifumi Takaori-Kondo
        Transplantation and Cellular Therapy, Jun. 2023
      • An adult case of refractory autoimmune neutropenia after liver transplantation.
        Huye Sun; Fumiya Wada; Junya Kanda; Chisaki Mizumoto; Takashi Ito; Yuuki Masano; Yoichiro Uchida; Etsurou Hatano; Kimiko Yurugi; Rie Hishida; Kouhei Yamashita; Akifumi Takaori-Kondo
        International journal of hematology, 21 Feb. 2023
      • 肝移植後に難治性自己免疫性好中球減少症を発症した成人の1例
        孫 胡曄; 和田 典也; 諫田 淳也; 水本 智咲; 山下 浩平; 高折 晃史; 伊藤 孝司; 政野 裕紀; 内田 洋一朗; 波多野 悦朗; 万木 紀美子; 菱田 理恵
        臨床血液, Feb. 2023
      • T-cell counts in peripheral blood at leukapheresis predict responses to subsequent CAR-T cell therapy
        Fumiya Wada; Tomoyasu Jo; Yasuyuki Arai; Toshio Kitawaki; Chisaki Mizumoto; Junya Kanda; Momoko Nishikori; Kouhei Yamashita; Miki Nagao; Akifumi Takaori-Kondo
        Scientific Reports, 04 Nov. 2022
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      • Burden of illness seen in hereditary angioedema in Japanese patients: Results from a patient reported outcome survey
        Beverley Yamamoto; Daisuke Honda; Isao Ohsawa; Kazumasa Iwamoto; Takahiko Horiuchi; Atsushi Fukunaga; Junichi Maehara; Kouhei Yamashita; Michihiro Hide
        Intractable & Rare Diseases Research, 28 Feb. 2023
      • Ph陰性B-ALLに対するブリナツモマブ治療中の採卵の実施可能性(Feasibility of fertility preservation during blinatumomab treatment for Ph-negative B-ALL)
        田代 裕介; 諫田 淳也; 家村 知樹; 近藤 忠一; 山下 浩平; 砂田 真澄; 堀江 昭史; 高折 晃史
        日本血液学会学術集会, Sep. 2021
      • Significance of Omitting Day 11 Mini-Dose Methotrexate for GVHD Prophylaxis After Unrelated Bone Marrow Transplantation
        Naokazu Nakamura; Fumiya Wada; Tadakazu Kondo; Kazunari Aoki; Yasuyuki Arai; Chisaki Mizumoto; Junya Kanda; Toshio Kitawaki; Kouhei Yamashita; Akifumi Takaori-Kondo
        Transplantation and Cellular Therapy, Nov. 2022
      • Decreased serum phosphate levels are a useful biomarker to predict occurrence and severity of cytokine release syndrome in chimeric antigen receptor T ‐cell therapy
        Naokazu Nakamura; Yasuyuki Arai; Toshio Kitawaki; Tomoyasu Jo; Chisaki Mizumoto; Junya Kanda; Momoko Nishikori; Kouhei Yamashita; Akifumi Takaori‐Kondo
        British Journal of Haematology, 11 Oct. 2022
      • Feasibility of ovarian stimulation for fertility preservation during and after blinatumomab treatment for Ph-negative B-cell acute lymphoblastic leukemia
        Yusuke Tashiro; Junya Kanda; Tomoki Iemura; Tadakazu Kondo; Kouhei Yamashita; Masumi Sunada; Akihito Horie; Akifumi Takaori-Kondo
        International Journal of Hematology, Sep. 2022
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      • Effects of combined test-dose and therapeutic drug monitoring strategy in exposure-directed busulfan
        Tomoki Iemura; Tadakazu Kondo; Atsushi Ueda; Takeshi Maeda; Toshio Kitawaki; Yasuyuki Arai; Junya Kanda; Takashi Ikeda; Kazunori Imada; Takayuki Ishikawa; Naoyuki Anzai; Mitsuru Itoh; Tomoharu Takeoka; Takashi Akasaka; Kazuhiro Yago; Akihito Yonezawa; Nobuyoshi Arima; Toshiyuki Kitano; Masaharu Nohgawa; Mitsumasa Watanabe; Toshinori Moriguchi; Kouhei Yamashita; Yasunori Ueda; Kana Matsumoto; Akifumi Takaori-Kondo
        05 Jul. 2022
      • Addition and drug monitoring of mycophenolate mofetil for GVHD prophylaxis in unrelated bone marrow transplantation
        Fumiya Wada; Tadakazu Kondo; Ryusuke Yamamoto; Takero Yamagiwa; Yasuyuki Arai; Chisato Mizumoto; Junya Kanda; Toshio Kitawaki; Kouhei Yamashita; Akifumi Takaori-Kondo
        Bone Marrow Transplantation, Jul. 2022
      • Coexistence of HLA and KIR ligand mismatches as a risk factor for viral infection early after cord blood transplantation
        Tomoki Iemura; Yasuyuki Arai; Toshio Kitawaki; Junya Kanda; Tadakazu Kondo; Yasunori Ueda; Takuto Mori; Kazunori Imada; Akihito Yonezawa; Kazuhiro Yago; Naoyuki Anzai; Shinichi Kotani; Masaharu Nohgawa; Toshiyuki Kitano; Mitsuru Itoh; Nobuyoshi Arima; Toshinori Moriguchi; Mitsumasa Watanabe; Masaaki Tsuji; Kouhei Yamashita; Akifumi Takaori-Kondo
        Bone Marrow Transplantation, May 2022
      • Small B-cell neoplasm responding to ibrutinib after 17 years of cold agglutinin disease symptom.
        Morimoto S; Shindo T; Iga Y; Morita M; Yurugi K; Masuda K; Hori H; Hishizawa M; Kondo T; Yamashita K; Haga H; Takaori-Kondo A
        Rinsho Ketsueki, Dec. 2021, Peer-reviewed, Invited
      • Activation of nucleotide-binding oligomerization domain 2 by muramyl dipeptide negatively regulates Toll-like receptor 9-mediated colonic inflammation through the induction of deubiquitinating enzyme A expression
        Yasuhiro Masuta; Kosuke Minaga; Masayuki Kurimoto; Ikue Sekai; Akane Hara; Naoya Omaru; Natsuki Okai; Yasuo Otsuka; Ryutaro Takada; Tomoe Yoshikawa; Sho Masaki; Ken Kamata; Hajime Honjo; Yasuyuki Arai; Kouhei Yamashita; Masatoshi Kudo; Tomohiro Watanabe
        International Immunology, 29 Sep. 2022
      • Drug monitoring for mycophenolic acid in graft-vs-host disease prophylaxis in cord blood transplantation.
        Muranushi H; Kanda J; Arai Y; Shindo T; Hishizawa M; Yamamoto T; Kondo T; Yamashita K; Matsubara K; Takaori-Kondo A
        British journal of clinical pharmacology, May 2020, Peer-reviewed
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      • 肺腺がんを合併した小リンパ球性リンパ腫の3例
        天ヶ瀬 寛記; 錦織 桃子; 秋山 大介; 赤荻 杏奈; 島津 裕; 近藤 忠一; 山下 浩平; 高折 晃史
        臨床血液, Feb. 2022
      • CD19-CAR-T療法後に汎血球減少を認めたびまん性大細胞型B細胞リンパ腫の1例
        天ヶ瀬 寛記; 岩崎 惇; 諫田 淳也; 島津 裕; 水本 智咲; 近藤 忠一; 山下 浩平; 高折 晃史
        臨床血液, Mar. 2021
      • Expression levels of cellular inhibitor of apoptosis proteins and colitogenic cytokines are inversely correlated with the activation of interferon regulatory factor 4
        Sho Masaki; Tomohiro Watanabe; Yasuyuki Arai; Ikue Sekai; Akane Hara; Masayuki Kurimoto; Yasuo Otsuka; Yasuhiro Masuta; Tomoe Yoshikawa; Ryutaro Takada; Ken Kamata; Kosuke Minaga; Kouhei Yamashita; Masatoshi Kudo
        Clinical and Experimental Immunology, 17 Jan. 2022
      • PET-CT評価に注意を要した悪性リンパ腫症例
        井上 令一; 錦織 桃子; 近藤 忠一; 山下 浩平; 高折 晃史; 藤本 正数
        臨床血液, Sep. 2021
      • サルコイドーシスの経過観察中に発症した肺門部の非ホジキンリンパ腫
        天ヶ瀬 寛記; 岩崎 惇; 進藤 岳郎; 諫田 淳也; 錦織 桃子; 近藤 忠一; 山下 浩平; 高折 晃史; 谷澤 公伸; 藤本 正数
        臨床血液, Sep. 2021
      • Next‐generation sequencing in two cases of de novo acute basophilic leukaemia
        Takuya Shimizu; Tadakazu Kondo; Yasuhito Nannya; Mizuki Watanabe; Toshio Kitawaki; Takero Shindo; Masakatsu Hishizawa; Kouhei Yamashita; Seishi Ogawa; Akifumi Takaori‐Kondo
        Journal of Cellular and Molecular Medicine, Jul. 2021
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      • Successful treatment with famciclovir for varicella zoster virus infection resistant to acyclovir.
        Tomomi Oka; Masakatsu Hishizawa; Kouhei Yamashita; Kimiyasu Shiraki; Akifumi Takaori-Kondo
        Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, May 2021
      • The diagnosis and treatment of hereditary angioedema patients in Japan: A patient reported outcome survey.
        Kazumasa Iwamoto; Beverley Yamamoto; Isao Ohsawa; Daisuke Honda; Takahiko Horiuchi; Akira Tanaka; Atsushi Fukunaga; Junichi Maehara; Kouhei Yamashita; Tomoyuki Akita; Michihiro Hide
        Allergology international : official journal of the Japanese Society of Allergology, Apr. 2021
      • Possible nosocomial transmission of virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation.
        Yoshiyuki Onda; Junya Kanda; Nozomu Hanaoka; Mizuki Watanabe; Yasuyuki Arai; Masakatsu Hishizawa; Tadakazu Kondo; Kouhei Yamashita; Miki Nagao; Tsuguto Fujimoto; Akifumi Takaori-Kondo
        Annals of hematology, Mar. 2021
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      • Favorable Outcomes after Single Cord Blood Transplantation for Patients with High-Risk Hematologic Diseases: A Single-Institute Retrospective Analysis.
        Fumiya Wada; Junya Kanda; Mizuki Watanabe; Yasuyuki Arai; Masakatsu Hishizawa; Tadakazu Kondo; Kouhei Yamashita; Akifumi Takaori-Kondo
        Transplantation and cellular therapy, 25 Feb. 2021
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      • Changes in tonsillolith characteristics detected in a follow-up CT study.
        Kouhei Yamashita; Masafumi Oda; Tatsurou Tanaka; Ikuko Nishida; Nao Wakasugi-Sato; Shinobu Matsumoto-Takeda; Manabu Habu; Teppei Sago; Osamu Takahashi; Hiroki Tsurushima; Shiro Tabe; Taishi Otani; Daigo Yoshiga; Masaaki Sasaguri; Takaaki Joujima; Yuichi Miyamura; Yasuhiro Morimoto
        BMC oral health, 16 Feb. 2021
      • Orthognathic Surgery in Hereditary Angioedema With Normal C1 Inhibitor: A Clinical Response to Concentrated C1 Inhibitor Against Angioedema Attack.
        Takuma Watanabe; Kouhei Yamashita; Kazuhisa Bessho
        Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, Feb. 2021
      • Survey of actual conditions of erythema marginatum as a prodromal symptom in Japanese patients with hereditary angioedema.
        Isao Ohsawa; Atsushi Fukunaga; Shinya Imamura; Kazumasa Iwamoto; Akio Tanaka; Michihiro Hide; Daisuke Honda; Kouhei Yamashita; Chisako Fujiwara; Osamu Ishikawa; Takeo Yamaguchi; Junichi Maehara; Tomoya Hirose; Masahiro Ieko; Kunihiko Umekita; Yuya Nakamura; Hiromichi Gotoh
        The World Allergy Organization journal, Feb. 2021
      • Impact of HLA class I allele-level mismatch on viral infection within 100 days after cord blood transplantation.
        Tomoki Iemura; Yasuyuki Arai; Junya Kanda; Toshio Kitawaki; Masakatsu Hishizawa; Tadakazu Kondo; Kouhei Yamashita; Akifumi Takaori-Kondo
        Scientific reports, 03 Dec. 2020
      • High-dose cytarabine chemotherapy (≥4 g/m2/day) before allogeneic hematopoietic stem cell transplantation for non-core-binding-factor AML in the first complete remission.
        Yosuke Nagahata; Tadakazu Kondo; Yuichiro Ono; Nobuhiro Hiramoto; Toshiyuki Kitano; Masakatsu Hishizawa; Kouhei Yamashita; Hisako Hashimoto; Takayuki Ishikawa; Akifumi Takaori-Kondo
        Leukemia & lymphoma, Dec. 2020
      • A case of allogeneic hematopoietic stem cell transplantation for primary plasma cell leukemia after treatment with daratumumab.
        Yoshihito Horisawa; Tadakazu Kondo; Masakatsu Hishizawa; Kouhei Yamashita; Akifumi Takaori-Kondo
        Annals of hematology, Nov. 2020
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      • ATG16L1 negatively regulates RICK/RIP2-mediated innate immune responses.
        Hajime Honjo; Tomohiro Watanabe; Yasuyuki Arai; Ken Kamata; Kosuke Minaga; Yoriaki Komeda; Kouhei Yamashita; Masatoshi Kudo
        International immunology, 10 Sep. 2020
      • Exaggerated neutrophil extracellular trap formation in Kawasaki disease: a key phenomenon behind the outbreak in western countries?
        Kouhei Yamashita; Akifumi Takaori-Kondo; Kiyomi Mizugishi
        Annals of the rheumatic diseases, 21 Aug. 2020
      • Lymphopenia at diagnosis predicts survival of patients with immunodeficiency-associated lymphoproliferative disorders.
        Mizuki Watanabe; Junya Kanda; Masakatsu Hishizawa; Momoko Nishikori; Tadakazu Kondo; Kouhei Yamashita; Akifumi Takaori-Kondo
        Annals of hematology, Jul. 2020, Peer-reviewed
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      • Activation of interferon regulatory factor 7 in plasmacytoid dendritic cells promotes experimental autoimmune pancreatitis.
        Kosuke Minaga; Tomohiro Watanabe; Yasuyuki Arai; Masahiro Shiokawa; Akane Hara; Tomoe Yoshikawa; Ken Kamata; Kouhei Yamashita; Masatoshi Kudo
        Journal of gastroenterology, May 2020, Peer-reviewed
      • Successful treatment of Hodgkin lymphoma-like EBV-associated post-transplant lymphoproliferative disorder following allogeneic hematopoietic stem cell transplantation with nivolumab.
        Fumiya Wada; Tadakazu Kondo; Momoko Nakamura; Kazuhisa Chonabayashi; Momoko Nishikori; Masakatsu Hishizawa; Kouhei Yamashita; Akifumi Takaori-Kondo
        Annals of hematology, Apr. 2020, Peer-reviewed
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      • 同種移植前後にgilteritinibを投与したFLT3-ITD変異陽性治療抵抗性急性骨髄性白血病の1例
        虎谷 和則; 光吉 貴哉; 家村 知樹; 新井 康之; 近藤 忠一; 山下 浩平; 高折 晃史
        臨床血液, Feb. 2020
      • 多発溶骨性病変と高カルシウム血症を伴った若年diffuse large B-cell lymphomaの1例
        増尾 優輝; 阪本 貴士; 北脇 年雄; 櫻田 紘基; 菱澤 方勝; 近藤 忠一; 山下 浩平; 高折 晃史
        臨床血液, Feb. 2020
      • 骨髄炎に続発した髄外腫瘤を伴う急性前骨髄球性白血病
        櫻田 紘基; 孫 春暁; 阪本 貴士; 進藤 岳郎; 菱澤 方勝; 近藤 忠一; 山下 浩平; 高折 晃史; 岩井 俊樹; 内山 人二
        臨床血液, Feb. 2020
      • Neutropenia and renal dysfunction due to intravesical cidofovir for virus-associated hemorrhagic cystitis after kidney and allogenic hematopoietic stem cell transplantations.
        Takuya Shimizu; Tadakazu Kondo; Kana Matsumoto; Masakatsu Hishizawa; Kouhei Yamashita; Akifumi Takaori-Kondo
        Transplant infectious disease : an official journal of the Transplantation Society, Dec. 2019
      • Acute myeloid leukemia with a cryptic NUP98/PRRX2 rearrangement developing after low-dose methotrexate therapy for rheumatoid arthritis.
        Kazuhisa Chonabayashi; Yoshinori Yoshida; Toshio Kitawaki; Yasuhito Nannya; Momoko Nakamura; Shinichiro Oshima; Masakatsu Hishizawa; Kouhei Yamashita; Seishi Ogawa; Akifumi Takaori-Kondo
        Annals of hematology, Dec. 2019, Peer-reviewed
      • NK-cell post-transplant lymphoproliferative disease with chronic active Epstein-Barr virus infection-like clinical findings.
        Tomoki Iemura; Tadakazu Kondo; Masakatsu Hishizawa; Kouhei Yamashita; Hiroshi Kimura; Akifumi Takaori-Kondo
        International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, Nov. 2019
      • Effectiveness of cord blood transplantation for the treatment of refractory angioimmunoblastic T-cell lymphoma: a series of three cases.
        Yasuhiro Kazuma; Yayoi Shimazu; Masakatsu Hishizawa; Momoko Nishikori; Toshiyuki Kitano; Tadakazu Kondo; Kouhei Yamashita; Akifumi Takaori-Kondo
        Bone marrow transplantation, Oct. 2019, Peer-reviewed
      • Metronidazole-induced encephalopathy during treatment for refractory diarrhea after cord blood transplantation.
        Tomoki Iemura; Toshiyuki Kitano; Akira Ishii; Masakatsu Hishizawa; Tadakazu Kondo; Kouhei Yamashita; Akifumi Takaori-Kondo
        Clinical journal of gastroenterology, Oct. 2019, Peer-reviewed
      • Impact of cumulative steroid dose on infectious diseases after allogenic hematopoietic stem cell transplantation.
        Watanabe M; Kanda J; Hishizawa M; Kondo T; Yamashita K; Takaori-Kondo A
        Transplant infectious disease : an official journal of the Transplantation Society, Apr. 2019, Peer-reviewed
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      • Lymphocyte Area Under the Curve as a Predictive Factor for Viral Infection after Allogenic Hematopoietic Stem Cell Transplantation.
        Watanabe M; Kanda J; Hishizawa M; Kondo T; Yamashita K; Takaori-Kondo A
        Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, Mar. 2019, Peer-reviewed
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      • Allogeneic hematopoietic stem cell transplantation for 8p11 myeloproliferative syndrome with BCR-FGFR1 gene rearrangement: a case report and literature review.
        Yoshinobu Konishi; Tadakazu Kondo; Kensuke Nakao; Kohusuke Asagoe; Yasuyuki Otsuka; Momoko Nishikori; Masakatsu Hishizawa; Kouhei Yamashita; Akifumi Takaori-Kondo
        Bone marrow transplantation, Feb. 2019, Peer-reviewed
      • [Successful treatment with recombinant thrombomodulin in transplant-associated thrombotic microangiopathy following HLA-haploidentical transplantation].
        Yasuyuki Otsuka; Tadakazu Kondo; Ryosuke Nomura; Kouhei Yamashita; Akifumi Takaori-Kondo
        [Rinsho ketsueki] The Japanese journal of clinical hematology, 2019
      • Effect of laminar air flow and building construction on aspergillosis in acute leukemia patients: a retrospective cohort study.
        Iwasaki M; Kanda J; Hishizawa M; Kitano T; Kondo T; Yamashita K; Takaori-Kondo A
        BMC infectious diseases, Jan. 2019, Peer-reviewed
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      • Impact of the Use and Type of Antibiotics on Acute Graft-versus-Host Disease.
        Nishi K; Kanda J; Hishizawa M; Kitano T; Kondo T; Yamashita K; Takaori-Kondo A
        Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, Nov. 2018, Peer-reviewed
      • Prognostic impact of activation-induced cytidine deaminase expression for patients with diffuse large B-cell lymphoma.
        Hiroshi Arima; Masakazu Fujimoto; Momoko Nishikori; Toshiyuki Kitano; Wataru Kishimoto; Masakatsu Hishizawa; Tadakazu Kondo; Kouhei Yamashita; Masahiro Hirata; Hironori Haga; Akifumi Takaori-Kondo
        Leukemia & lymphoma, Sep. 2018, Peer-reviewed
      • Familial Mediterranean Fever Mutations in a Patient with Periodic Episodes of Systemic Pain Deriving from Cancer Bone Metastases.
        Yamashita K; Mizugishi K; Takaori-Kondo A
        Internal medicine (Tokyo, Japan), May 2018, Peer-reviewed
      • Occurrence and improvement of renal dysfunction and serum potassium abnormality during administration of liposomal amphotericin B in patients with hematological disorders: A retrospective analysis
        Hiroyuki Yamazaki; Tadakazu Kondo; Kazunai Aoki; Kouhei Yamashita; Akifumi Takaori-Kondo
        Diagnostic Microbiology and Infectious Disease, 01 Feb. 2018, Peer-reviewed
      • A single-center retrospective analysis of extramedullary relapse after allogeneic stem cell transplantation for myeloid neoplasms
        Takeshi Ito; Tadakazu Kondo; Kouhei Yamashita; Akifumi Takaori-Kondo
        Journal of Hematopoietic Cell Transplantation, 2018
      • Chronic Kidney Disease in Long-Term Survivors after Allogeneic Hematopoietic Stem Cell Transplantation: Retrospective Analysis at a Single Institute
        Tomoyasu Jo; Yasuyuki Arai; Tadakazu Kondo; Toshiyuki Kitano; Masakatsu Hishizawa; Kouhei Yamashita; Akifumi Takaori-Kondo
        BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, Dec. 2017, Peer-reviewed
      • Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background
        Kiyomi Mizugishi; Kouhei Yamashita
        FASEB JOURNAL, Dec. 2017, Peer-reviewed
      • Chronic Fibro-Inflammatory Responses in Autoimmune Pancreatitis Depend on IFN-alpha and IL-33 Produced by Plasmacytoid Dendritic Cells
        Tomohiro Watanabe; Kouhei Yamashita; Yasuyuki Arai; Kosuke Minaga; Ken Kamata; Tomoyuki Nagai; Yoriaki Komeda; Mamoru Takenaka; Satoru Hagiwara; Hiroshi Ida; Toshiharu Sakurai; Naoshi Nishida; Warren Strober; Masatoshi Kudo
        JOURNAL OF IMMUNOLOGY, May 2017, Peer-reviewed
      • Outcome of allogeneic hematopoietic stem cell transplantation in cases of mature T/NK-cell neoplasms: a single-center retrospective analysis
        Hiroyuki Yamazaki; Kazunari Aoki; Tadakazu Kondo; Momoko Nishikori; Toshiyuki Kitano; Masakatsu Hishizawa; Kouhei Yamashita; Akifumi Takaori-Kondo
        ANNALS OF HEMATOLOGY, Feb. 2017, Peer-reviewed
      • A rare case of adult autoimmune neutropenia successfully treated with prednisolone
        Fujita Mari; Kawabata Hiroshi; Oka Tomomi; Hishizawa Masakatsu; Kitano Toshiyuki; Kondo Tadakazu; Yamashita Kohei; Yurugi Kimiko; Hirai Hideyo; Maekawa Taira; Takaori-Kondo Akifumi
        Internal Medicine, 2017
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      • Isolation of mesenchymal stromal/stem cells from cryopreserved umbilical cord blood cells
        Fujita M; Kawabata H; Oka T; Hishizawa M; Kitano T; Kondo T; Yamashita K; Yurugi K; Hirai H; Maekawa T; Takaori-Kondo A
        Intern Med, 2017, Peer-reviewed
      • Follicular lymphoma with plasmacytic differentiation accompanied by monoclonal IgG gammopathy.
        Oka T; Kobayashi M; Komori T; Nakamine H; Kitano T; Hishizawa M; Kondoh T; Yamashita K; Takaori-Kondo A
        [Rinsho ketsueki] The Japanese journal of clinical hematology, 2017, Peer-reviewed
      • [FLT3 Mutations in Acute Myeloid Leukemia].
        Shoji T; Kida Y; Yamashita K; Ichiyama S
        Rinsho byori. The Japanese journal of clinical pathology, Jan. 2017, Peer-reviewed
      • IgG4-Related Disease and Innate Immunity
        Tomohiro Watanabe; Kouhei Yamashita; Masatoshi Kudo
        IGG4-RELATED DISEASE, 2017, Peer-reviewed
      • Successful treatment with intravesical cidofovir for virus-associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation: A case report and a review of the literature
        Maki Sakurada; Tadakazu Kondo; Masayuki Umeda; Hiroshi Kawabata; Kouhei Yamashita; Akifum Takaori-Kondo
        JOURNAL OF INFECTION AND CHEMOTHERAPY, Jul. 2016, Peer-reviewed
      • Plasmacytoid Dendritic Cell Activation and IFN-alpha Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis
        Yasuyuki Arai; Kouhei Yamashita; Katsutoshi Kuriyama; Masahiro Shiokawa; Yuzo Kodama; Toshiharu Sakurai; Kiyomi Mizugishi; Kazushige Uchida; Norimitsu Kadowaki; Akifumi Takaori-Kondo; Masatoshi Kudo; Kazuichi Okazaki; Warren Strober; Tsutomu Chiba; Tomohiro Watanabe
        JOURNAL OF IMMUNOLOGY, Oct. 2015, Peer-reviewed
      • Increased bone marrow uptake of 18F-FDG in leukemia patients: preliminary findings
        Maya Kato Arimoto; Yuji Nakamoto; Koya Nakatani; Takayoshi Ishimori; Kouhei Yamashita; Akifumi Takaori-Kondo; Kaori Togashi
        SPRINGERPLUS, Sep. 2015, Peer-reviewed
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      • Phagocytosis by human monocytes is required for the secretion of presepsin
        Yasuyuki Arai; Kiyomi Mizugishi; Kazuhiko Nonomura; Katsuki Naitoh; Akifumi Takaori-Kondo; Kouhei Yamashita
        JOURNAL OF INFECTION AND CHEMOTHERAPY, Aug. 2015, Peer-reviewed
      • Increased number of peripheral CD8(+) T cells but not eosinophils is associated with late-onset skin reactions caused by bendamustine
        Momoko Nishikori; Toshiyuki Kitano; Masayuki Kobayashi; Masakatsu Hishizawa; Toshio Kitawaki; Tadakazu Kondo; Kouhei Yamashita; Hiroshi Kawabata; Norimitsu Kadowaki; Yusuke Takei; Hironori Haga; Akifumi Takaori-Kondo
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Jul. 2015, Peer-reviewed
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      • Enhancement of neutrophil autophagy by an IVIG preparation against multidrug-resistant bacteria as well as drug-sensitive strains
        Hiroshi Itoh; Hidemasa Matsuo; Naoko Kitamura; Sho Yamamoto; Takeshi Higuchi; Hiromu Takematsu; Yasuhiko Kamikubo; Tadakazu Kondo; Kouhei Yamashita; Masataka Sasada; Akifumi Takaori-Kondo; Souichi Adachi
        JOURNAL OF LEUKOCYTE BIOLOGY, Jul. 2015, Peer-reviewed
      • Risk factors for late-onset neutropenia after rituximab treatment of B-cell lymphoma
        Yasuyuki Arai; Kouhei Yamashita; Kiyomi Mizugishi; Momoko Nishikori; Masakatsu Hishizawa; Tadakazu Kondo; Toshiyuki Kitano; Hiroshi Kawabata; Norimitsu Kadowaki; Akifumi Takaori-Kondo
        Hematology, May 2015, Peer-reviewed
      • [Clinical value of 18F-FDG-PET and 11C-MET-PET in patients with plasma cell malignancy].
        Kobayashi M; Yamashita K; Takaori-Kondo A
        Nihon rinsho. Japanese journal of clinical medicine, Jan. 2015, Peer-reviewed
      • Monitoring mycophenolate mofetil is necessary for the effective prophylaxis of acute GVHD after cord blood transplantation
        Arai, Y; Kondo, T; Kitano, T; Hishizawa, M; Yamashita, K; Kadowaki, N; Yamamoto, T; Yano, I; Matsubara, K; Takaori-Kondo, A
        Bone Marrow Transplantation, 2015, Peer-reviewed
      • Sphingolipid Pathway Regulates Innate Immune Responses at the Fetomaternal Interface during Pregnancy
        Kiyomi Mizugishi; Takuya Inoue; Hiroshi Hatayama; Jacek Bielawski; Jason S. Pierce; Yukiyasu Sato; Akifunni Takaori-Kondo; Ikuo Konishi; Kouhei Yamashita
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 2015, Peer-reviewed
      • [Usefulness of quantitative PCR in biopsy specimens for early therapeutic intervention in gastro-intestinal cytomegalovirus infections after allogeneic stem cell transplantation].
        Arai Y; Kondo T; Kitano T; Hishizawa M; Yamashita K; Kadowaki N; Takaori-Kondo A
        [Rinsho ketsueki] The Japanese journal of clinical hematology, Dec. 2014, Peer-reviewed
      • Nuclear factor Y (NF-Y) regulates the proximal promoter activity of the mouse collagen alpha 1(XI) gene (Col11a1) in chondrocytes
        Mariko Hida; Ryoji Hamanaka; Osamu Okamoto; Kouhei Yamashita; Takako Sasaki; Hidekatsu Yoshioka; Noritaka Matsuo
        IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, Apr. 2014, Peer-reviewed
      • A case of minor BCR-ABL1 positive acute lymphoblastic leukemia following essential thrombocythemia and originating from a clone distinct from that harboring the JAK2-V617F mutation
        Yuya Nagai; Masahiro Kawahara; Noriko Sugino; Yayoi Shimazu; Masakatsu Hishizawa; Kouhei Yamashita; Norimitsu Kadowaki; Akifumi Takaori-Kondo
        Experimental Hematology and Oncology, 17 Feb. 2014, Peer-reviewed
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      • Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation
        Yasuyuki Arai; Yoko Nishinaka; Toshiyuki Arai; Makiko Morita; Kiyomi Mizugishi; Souichi Adachi; Akifumi Takaori-Kondo; Tomohiro Watanabe; Kouhei Yamashita
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jan. 2014, Peer-reviewed
      • Risk factors for hypogammaglobulinemia after allo-SCT
        Y. Arai; K. Yamashita; K. Mizugishi; T. Kondo; T. Kitano; M. Hishizawa; N. Kadowaki; A. Takaori-Kondo
        Bone Marrow Transplantation, 2014, Peer-reviewed
      • NOD2 down-regulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6
        Chiba T; Shimosegawa T; Strober W; Watanabe T; Meng G; Asano N; Arai Y; Yamashita K; Kudo M; Sakurai T; Kitani A; Fuss I.J
        Mucosal Immunol, 2014, Peer-reviewed
      • CKIP-1 Is an Intrinsic Negative Regulator of T-Cell Activation through an Interaction with CARMA1
        Takashi Sakamoto; Masayuki Kobayashi; Kohei Tada; Masanobu Shinohara; Katsuhiro Io; Kayoko Nagata; Fumie Iwai; Yoko Takiuchi; Yasuyuki Arai; Kouhei Yamashita; Keisuke Shindo; Norimitsu Kadowaki; Yoshio Koyanagi; Akifumi Takaori-Kondo
        PLOS ONE, Jan. 2014, Peer-reviewed
      • Serum Neutrophil Extracellular Trap Levels Predict Thrombotic Microangiopathy after Allogeneic Stem Cell Transplantation
        Yasuyuki Arai; Kouhei Yamashita; Kiyomi Mizugishi; Tomohiro Watanabe; Soichiro Sakamoto; Toshiyuki Kitano; Tadakazu Kondo; Hiroshi Kawabata; Norimitsu Kadowaki; Akifumi Takaori-Kondo
        Biology of Blood and Marrow Transplantation, Dec. 2013, Peer-reviewed
      • Prolonged ictal monoparesis with parietal Periodic Lateralised Epileptiform Discharges (PLEDs)
        Takashi Murahara; Masako Kinoshita; Kiyohide Usami; Masashi Matsui; Kouhei Yamashita; Ryosuke Takahashi; Akio Ikeda
        Epileptic Disorders, Jun. 2013, Peer-reviewed
      • The implications of myelodysplastic syndrome - associated chromosomal abnormalities in the development of graft-versus-host disease
        Yasuyuki Arai; Kouhei Yamashita; Kiyomi Mizugishi; Akifumi Takaori-Kondo; Tsutomu Chiba; Tomohiro Watanabe
        European Journal of Haematology, Jun. 2013, Peer-reviewed
      • Clinical value of C-11-methionine PET/CT in patients with plasma cell malignancy: comparison with F-18-FDG PET/CT
        Yuji Nakamoto; Kensuke Kurihara; Masatoshi Nishizawa; Kouhei Yamashita; Koya Nakatani; Tadakazu Kondo; Akifumi Takaori-Kondo; Kaori Togashi
        EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, May 2013, Peer-reviewed
      • Enhanced generation of reactive oxygen species by interferon-gamma may have contributed to successful treatment of invasive pulmonary aspergillosis in a patient with chronic granulomatous disease
        Kouhei Yamashita; Takashi Miyoshi; Yasuyuki Arai; Kiyomi Mizugishi; Akifumi Takaori-Kondo; Takehiko Ueyama
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Apr. 2013, Peer-reviewed
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      • Human herpesvirus-6 encephalitis during hematopoietic stem cell transplantation leads to poor prognosis
        Y. Shimazu; T. Kondo; T. Ishikawa; K. Yamashita; A. Takaori-Kondo
        TRANSPLANT INFECTIOUS DISEASE, Apr. 2013, Peer-reviewed
      • Familial Mediterranean fever mutations in a patient with recurrent episodes of acute respiratory distress syndrome
        Yasuyuki Arai; Kouhei Yamashita; Kiyomi Mizugishi; Tomohiro Watanabe; Tadakazu Kondo; Toshiyuki Kitano; Hiroshi Kawabata; Norimitsu Kadowaki; Akifumi Takaori-Kondo
        CLINICAL IMMUNOLOGY, Apr. 2013, Peer-reviewed
      • Toll-like receptor activation in basophils contributes to the development of IgG4-related disease
        Tomohiro Watanabe; Kouhei Yamashita; Toshiharu Sakurai; Masatoshi Kudo; Masahiro Shiokawa; Norimitsu Uza; Yuzo Kodama; Kazushige Uchida; Kazuichi Okazaki; Tsutomu Chiba
        Journal of Gastroenterology, Feb. 2013, Peer-reviewed
      • Syndrome of inappropriate antidiuretic hormone secretion induced by Tacrolimus Following Allogeneic Cord Blood Transplantation
        Yasuyuki Arai; Tadakazu Kondo; Toshiyuki Kitano; Kouhei Yamashita; Norimitsu Kadowaki; Akifumi Takaori-Kondo
        Internal Medicine, 2013, Peer-reviewed
      • Differing impacts of pretransplant serum ferritin and C-reactive protein levels on the incidence of chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
        Soichiro Sakamoto; Hiroshi Kawabata; Junya Kanda; Tatsuki Uchiyama; Chisaki Mizumoto; Tadakazu Kondo; Kouhei Yamashita; Tatsuo Ichinohe; Takayuki Ishikawa; Norimitsu Kadowaki; Akifumi Takaori-Kondo
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Jan. 2013, Peer-reviewed
      • Long-term remission in patients with plasma cell myeloma after reduced-intensity conditioning allogeneic hematopoietic stem cell transplantation::A 10-year single-center experience
        Mori Minako; Kondo Tadakazu; Hishizawa Masakatsu; Nishikori Momoko; Yamashita Kouhei; Ichinohe Tatsuo; Kadowaki Norimitsu; Ishikawa Takayuki; Takaori-Kondo Akifumi
        Journal of Hematopoietic Cell Transplantation, 2013
      • Involvement of activation of toll-like receptors and nucleotide-binding oligomerization domain-like receptors in enhanced IgG4 responses in autoimmune pancreatitis
        Tomohiro Watanabe; Kouhei Yamashita; Saori Fujikawa; Toshiharu Sakurai; Masatoshi Kudo; Masahiro Shiokawa; Yuzo Kodama; Kazushige Uchida; Kazuichi Okazaki; Tsutomu Chiba
        ARTHRITIS AND RHEUMATISM, Mar. 2012, Peer-reviewed
      • Involvement of activation of toll-like receptors and nucleotide-binding oligomerization domain-like receptors in enhanced IgG4 responses in autoimmune pancreatitis
        Tomohiro Watanabe; Kouhei Yamashita; Saori Fujikawa; Toshiharu Sakurai; Masatoshi Kudo; Masahiro Shiokawa; Yuzo Kodama; Kazushige Uchida; Kazuichi Okazaki; Tsutomu Chiba
        ARTHRITIS AND RHEUMATISM, Mar. 2012, Peer-reviewed
      • Singlet oxygen is essential for neutrophil extracellular trap formation
        Yoko Nishinaka; Toshiyuki Arai; Souichi Adachi; Akifumi Takaori-Kondo; Kouhei Yamashita
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Sep. 2011, Peer-reviewed
      • Control of an outbreak of carbapenem-resistant Pseudomonas aeruginosa in a haemato-oncology unit
        M. Nagao; Y. Iinuma; J. Igawa; T. Saito; K. Yamashita; T. Kondo; A. Matsushima; S. Takakura; A. Takaori-Kondo; S. Ichiyama
        JOURNAL OF HOSPITAL INFECTION, Sep. 2011, Peer-reviewed
      • Clinical significance of subcategory and severity of chronic graft-versus-host disease evaluated by National Institutes of Health consensus criteria
        Takayuki Sato; Tatsuo Ichinohe; Junya Kanda; Kouhei Yamashita; Tadakazu Kondo; Takayuki Ishikawa; Takashi Uchiyama; Akifumi Takaori-Kondo
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Apr. 2011, Peer-reviewed
      • Pretransplant serum ferritin and C-reactive protein as predictive factors for early bacterial infection after allogeneic hematopoietic cell transplantation
        J. Kanda; C. Mizumoto; T. Ichinohe; H. Kawabata; T. Saito; K. Yamashita; T. Kondo; S. Takakura; S. Ichiyama; T. Uchiyama; T. Ishikawa
        BONE MARROW TRANSPLANTATION, Feb. 2011, Peer-reviewed
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      • Neurolymphomatosis as a manifestation of relapsed primary cardiac lymphoma
        Masatoshi Nishizawa; Kouhei Yamashita; Yuji Nakamoto; Shin-ichi Kotani; Tadakazu Kondo; Akifumi Takaori-Kondo
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Dec. 2010, Peer-reviewed
      • The role of endothelial interleukin-8/NADPH oxidase 1 axis in sepsis
        Takashi Miyoshi; Kouhei Yamashita; Toshiyuki Arai; Kokichi Yamamoto; Kiyomi Mizugishi; Takashi Uchiyama
        IMMUNOLOGY, Nov. 2010, Peer-reviewed
      • The Rapid Induction of HLA-E Is Essential for the Survival of Antigen-Activated Naive CD4 T Cells from Attack by NK Cells
        Sumiko Takao; Takayuki Ishikawa; Kouhei Yamashita; Takashi Uchiyama
        JOURNAL OF IMMUNOLOGY, Nov. 2010, Peer-reviewed
      • Impact of discontinuing fluoroquinolone prophylaxis on early mortality after allogeneic marrow or peripheral blood SCT with myeloablative conditioning
        J. Kanda; T. Ichinohe; T. Saito; K. Yamashita; T. Kondo; T. Ishikawa; S. Ichiyama; T. Uchiyama
        BONE MARROW TRANSPLANTATION, Aug. 2010, Peer-reviewed
      • C-11-Methionine PET/CT for multiple myeloma
        Masatoshi Nishizawa; Yuji Nakamoto; Tsuyoshi Suga; Toshiyuki Kitano; Takayuki Ishikawa; Kouhei Yamashita
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Jun. 2010, Peer-reviewed
      • Edaravone directly reacts with singlet oxygen and protects cells from attack
        Yoko Nishinaka; Hiroko Mori; Nobuyuki Endo; Takashi Miyoshi; Kouhei Yamashita; Souichi Adachi; Toshiyuki Arai
        LIFE SCIENCES, May 2010, Peer-reviewed
      • Substituent Effects of Pterin Derivatives on Singlet Oxygen Scavenging Activity
        Hiroko Mori; Yoko Nishinaka; Mitsuru Nonogawa; Piyanart Sommani; Keisuke Makino; Kouhei Yamashita; Toshiyuki Arai
        BIOLOGICAL & PHARMACEUTICAL BULLETIN, May 2010, Peer-reviewed
      • Gastrointestinal follicular lymphoma: review of the literature
        Shuji Yamamoto; Hiroshi Nakase; Kouhei Yamashita; Minoru Matsuura; Mariko Takada; Chiharu Kawanami; Tsutomu Chiba
        JOURNAL OF GASTROENTEROLOGY, Apr. 2010, Peer-reviewed
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      • NB4 cells treated with all-trans retinoic acid generate toxic reactive oxygen species that cause endothelial hyperpermeability
        Takashi Miyoshi; Toshiyuki Arai; Kouhei Yamashita; Masataka Sasada; Takashi Uchiyama
        LEUKEMIA RESEARCH, Mar. 2010, Peer-reviewed
      • [Neutrophil functions].
        K. Yamashita; T. Miyoshi
        Nippon rinsho. Japanese journal of clinical medicine, 2010, Peer-reviewed
      • Clinical Significance of Serum Hepcidin Levels on Early Infectious Complications in Allogeneic Hematopoietic Stem Cell Transplantation
        Junya Kanda; Chisaki Mizumoto; Hiroshi Kawabata; Tatsuo Ichinohe; Hideyuki Tsuchida; Naohisa Tomosugi; Keitaro Matsuo; Kouhei Yamashita; Tadakazu Kondo; Takayuki Ishikawa; Takashi Uchiyama
        BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, Aug. 2009, Peer-reviewed
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      • Successful treatment with intravenous colistin for sinusitis, orbital cellulites, and pneumonia caused by multidrug-resistant metallo-beta-lactamase-producing Pseudomonas aeruginosa in a patient with acute myeloid leukemia
        Takashi Saito; Akifumi Takaori-Kondo; Masaharu Tashima; Kohei Yamashita; Yoshitsugu Iinuma; Shunji Takakura; Miki Nagao; Tatsuo Ichinohe; Takayuki Ishikawa; Takashi Uchiyama; Satoshi Ichiyama
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Jun. 2009, Peer-reviewed
      • MALT lymphoma of the thymus with Sjogren's syndrome: biphasic changes in serological abnormalities over a 4-year period following thymectomy
        Takashi Sakamoto; Kouhei Yamashita; Chisaki Mizumoto; Maki Ueda; Tomoharu Takeoka; Terutoshi Hishita; Shigefusa Hada; Tatsuharu Ohno
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Jun. 2009, Peer-reviewed
      • Clinical challenges and images in GI. Image 4. Transplant-associated thrombotic microangiopathy of the colon accompanied by graft-versus-host disease.
        Shuji Yamamoto; Hiroshi Nakase; Tsutomu Chiba; Kouhei Yamashita; Masafumi Ito
        Gastroenterology, Jun. 2009, Peer-reviewed
      • Mycophenolate mofetil combined with tacrolimus and minidose methotrexate after unrelated donor bone marrow transplantation with reduced-intensity conditioning
        Chisaki Mizumoto; Junya Kanda; Tatsuo Ichinohe; Takayuki Ishikawa; Masashi Matsui; Norimitsu Kadowaki; Tadakazu Kondo; Kazunori Imada; Masakatsu Hishizawa; Hiroshi Kawabata; Momoko Nishikori; Kouhei Yamashita; Akifumi Takaori-Kondo; Toshiyuki Hori; Takashi Uchiyama
        INTERNATIONAL JOURNAL OF HEMATOLOGY, May 2009, Peer-reviewed
      • Simultaneous Occurrence of Inflammatory Bowel Disease and Myelodysplastic Syndrome due to Chromosomal Abnormalities in Bone Marrow Cells
        Fumiyasu Nakamura; Tomohiro Watanabe; Kimiko Hori; Yoshiaki Ohara; Kouhei Yamashita; Yoshihisa Tsuji; Yoshihide Ueda; Sakae Mikami; Hiroshi Nakase; Tsutomu Chiba
        DIGESTION, 2009, Peer-reviewed
      • 無症状で発見された心臓原発リンパ腫の一例
        仁木俊一郎; 中尾哲史; 田村俊寛; 尾野亘; 木村剛; 西澤正俊; 山下浩平; 辻崇
        日本循環器学会近畿地方会(Web), 2009
      • Clinical Significance of Severity and Subcategory of Chronic GVHD Evaluated by NIH Consensus Criteria
        Sato, Takayuki; Ichinohe, Tatsuo; Kanda, Junya; Yamashita, Kouhei; Kondo, Tadakazu; Ishikawa, Takayuki; Uchiyama, Takashi
        BLOOD, 2009
      • alpha-Phenyl-N-tert-butyl Nitrone Has Scavenging Activity Against Singlet Oxygen(O-1(2)) and Attenuates O-1(2)-Induced Neuronal Cell Death
        Anna Kawai; Yoko Nishinaka; Toshiyuki Arai; Kiichi Hirota; Hiroko Mori; Nobuyuki Endo; Takashi Miyoshi; Kouhei Yamashita; Masataka Sasada
        JOURNAL OF PHARMACOLOGICAL SCIENCES, Dec. 2008, Peer-reviewed
      • Ozone production by amino acids contributes to killing of bacteria
        Kouhei Yamashita; Takashi Miyoshi; Toshiyuki Arai; Nobuyuki Endo; Hiroshi Itoh; Keisuke Makino; Kiyomi Mizugishi; Takashi Uchiyama; Masataka Sasada
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Nov. 2008, Peer-reviewed
      • Effects of injectable propofol emulsion on singlet oxygen released from activated human neutrophils and that chemically generated
        Chika Senda; Yoko Nishinaka; Toshiyuki Arai; Hajime Segawa; Hiroko Mori; Mitsuru Nonogawa; Nobuyuki Endo; Takashi Miyoshi; Kouhei Yamashita; Masataka Sasada
        JOURNAL OF PHARMACOLOGICAL SCIENCES, Aug. 2008, Peer-reviewed
      • Anticancer photodynamic and non-photodynamic effects of pterin derivatives on a pancreatic cancer cell line
        Takashi Miyoshi; Toshlyuki Arai; Mitsuru Nonogawa; Keisuke Makino; Hiroko Mori; Kouhei Yamashita; Masataka Sasada
        JOURNAL OF PHARMACOLOGICAL SCIENCES, Jun. 2008, Peer-reviewed
      • The radical scavenger edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) reacts with a pterin derivative and produces a cytotoxic substance that induces intracellular reactive oxygen species generation and cell death
        Toshiyuki Arai; Mitsuru Nonogawa; Keisuke Makino; Nobuyuki Endo; Hiroko Mori; Takashi Miyoshi; Kouhei Yamashita; Masataka Sasada; Masahiro Kakuyama; Kazuhiko Fukuda
        JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Feb. 2008, Peer-reviewed
      • Familial Mediterranean fever gene as a possible modifier of sweet syndrome with chronic myelogenous leukemia
        Takashi Miyoshi; Kouhei Yamashita; Tatsuharu Ohno; Taisuke Izumi; Akifumi Takaori-Kondo; Masataka Sasada; Takashi Uchiyama
        ACTA HAEMATOLOGICA, 2008, Peer-reviewed
      • Reactivation of Human Herpes Virus 6 (HHV6) during Hematopoietic Stem Cell Transplantation: Risk Factor Analysis of HHV6 Encephalitis and Survival
        Shimazu, Yutaka; Ishikawa, Takayuki; Ichinohe, Tatsuo; Kondo, Tadakazu; Yamashita, Kouhei; Maruyama, Wataru; Uchiyama, Takashi
        BLOOD, 2008
      • Inhibitory effect of 6-formylpterin on HIF-1 alpha protein accumulation
        Piyanart Sommani; Kouhei Yamashita; Takashi Miyoshi; Hiroko Tsunemine; Tsutomu Kodaki; Hiroko Mori; Kiichi Hirota; Toshiyuki Arai; Masataka Sasada; Keisuke Makino
        BIOLOGICAL & PHARMACEUTICAL BULLETIN, Nov. 2007, Peer-reviewed
      • Analysis of serum angiogenic factors in a young multiple myeloma patient with high-output cardiac failure
        Kazunari Sasaki; Kouhei Yamashita; Takashi Miyoshi; Yutaka Furukawa; Takeshi Kimura; Toru Kita; Tatsuo Ichinohe; Takayuki Ishikawa; Masataka Sasada; Takashi Uchiyama
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Jul. 2007, Peer-reviewed
      • Effects of edaravone on singlet oxygen released from activated human neutrophils
        Piyanart Sommani; Toshiyuki Arai; Kouhei Yamashita; Takashi Miyoshi; Hiroko Mori; Masataka Sasada; Keisuke Makino
        JOURNAL OF PHARMACOLOGICAL SCIENCES, Jan. 2007, Peer-reviewed
      • Leukemic and meningeal relapse of CD5(+) intravascular large B-Cell lymphoma with down-modulation of CD20 after rituximab therapy
        Tatsuharu Ohno; Takashi Sakamoto; Chisaki Mizumoto; Takashi Miyoshi; Maki Ueda; Tomoharu Takeoka; Kouhei Yamashita; Terutoshi Hishita; Shigefusa Hada
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Jul. 2006, Peer-reviewed
      • LPS-induced ROS generation and changes in glutathione level and their relation to the maturation of human monocyte-derived dendritic cells
        H Yamada; T Arai; N Endo; K Yamashita; K Fukuda; M Sasada; T Uchiyama
        LIFE SCIENCES, Jan. 2006, Peer-reviewed
      • Unique abnormalities of CD4(+) and CD8(+) central memory cells associated with chronic graft-versus-host disease improve after extracorporeal photopheresis
        K Yamashita; ME Horwitz; A Kwatemaa; E Nomicos; K Castro; R Sokolic; SF Foster; M Garofalo; U Choi; M Ryherd; MR Brown; SF Leitman; AS Wayne; DH Fowler; MR Bishop; RW Childs; AJ Barrett; SZ Pavletic; HL Malech
        BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, Jan. 2006, Peer-reviewed
      • Etodolac使用中にRichter's syndromeを発症したCLLの一症例
        水本 智咲; 阪本 貴士; 上田 真紀; 竹岡 友晴; 山下 浩平; 日下 輝俊; 波田 重英; 大野 辰治
        日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2005
      • Bortezomibが著効を示した治療抵抗性多発性骨髄腫の一例
        大野 辰治; 水本 智咲; 阪本 貴士; 上田 真紀; 竹岡 友晴; 山下 浩平; 日下 輝俊; 波田 重英
        日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2005
      • Sjoegren症候群に合併した,RF活性をもつIgA型M蛋白血症を伴った胸腺MALTomaの症例
        阪本 貴士; 山下 浩平; 水本 智咲; 上田 真紀; 竹岡 友晴; 日下 輝俊; 波田 重英; 大野 辰治
        日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2005
      • Photodynamic effects of a novel pterin derivative on a pancreatic cancer cell line
        H Yamada; T Arai; N Endo; K Yamashita; M Nonogawa; K Makino; K Fukuda; M Sasada; T Uchiyama
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Aug. 2005, Peer-reviewed
      • Nitric oxide derived from human umbilical vein endothelial cells inhibits transendothelial migration of neutrophils
        S Oka; M Sasada; K Yamamoto; M Nohgawa; A Takahashi; K Yamashita; H Yamada; T Uchiyama
        INTERNATIONAL JOURNAL OF HEMATOLOGY, Apr. 2005, Peer-reviewed
      • Short-term delay of Fas-stimulated apoptosis by GM-CSF as a result of temporary suppression of FADD recruitment in neutrophils: evidence implicating phosphatidylinositol 3-kinase and MEK1-ERK1/2 pathways downstream of classical protein kinase C
        Y Kotone-Miyahara; K Yamashita; KK Lee; S Yonehara; T Uchiyama; M Sasada; A Takahashi
        JOURNAL OF LEUKOCYTE BIOLOGY, Nov. 2004, Peer-reviewed
      • Nuclear-localizing O-6-benzylguanine-resistant GFP-MGMT fusion protein as a novel in vivo selection marker
        U Choi; SS DeRavin; K Yamashita; N Whiting-Theobald; GF Linton; NA Loktionova; AE Pegg; HL Malech
        EXPERIMENTAL HEMATOLOGY, Aug. 2004, Peer-reviewed
      • Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cells
        K Yamashita; U Choi; PC Woltz; SF Foster; MC Sneller; F Hakim; DH Fowler; MR Bishop; SZ Pavletic; M Tamari; K Castro; AJ Barrett; RW Childs; GG Illei; SF Leitman; HL Malech; ME Horwitz
        BLOOD, May 2004, Peer-reviewed
      • Effects of intracellular reactive oxygen species generated by 6-formylpterin on T cell functions
        T Arai; H Yamada; T Namba; H Mori; H Ishii; K Yamashita; M Sasada; K Makino; K Fukuda
        BIOCHEMICAL PHARMACOLOGY, Mar. 2004, Peer-reviewed
      • Effects of 6-formylpterin as an internal source of hydrogen peroxide on cell death of human peripheral blood leukocytes
        M Nishioka; T Arai; K Yamashita; M Sasada; H Mori; H Ishii; K Tajima; K Makino; K Fukuda
        LIFE SCIENCES, May 2003, Peer-reviewed
      • Effects of 6-formylpterin as an internal source of hydrogen peroxide on cell death of human peripheral blood leukocytes
        M Nishioka; T Arai; K Yamashita; M Sasada; H Mori; H Ishii; K Tajima; K Makino; K Fukuda
        LIFE SCIENCES, May 2003, Peer-reviewed
      • Calpain-mediated X-linked inhibitor of apoptosis degradation in neutrophil apoptosis and its impairment in chronic neutrophilic leukemia
        S Kobayashi; K Yamashita; T Takeoka; T Ohtsuki; Y Suzuki; R Takahashi; K Yamamoto; SH Kaufmann; T Uchiyama; M Sasada; A Takahashi
        JOURNAL OF BIOLOGICAL CHEMISTRY, Sep. 2002, Peer-reviewed
      • 6-formylpterin intracellularly generates hydrogen peroxide and restores the impaired bactericidal activity of human neutrophils
        K Yamashita; T Arai; K Fukuda; H Mori; H Ishii; M Nishioka; K Tajima; K Makino; M Sasada
        BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Nov. 2001, Peer-reviewed
      • 6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation
        T Arai; N Endo; K Yamashita; M Sasada; H Mori; H Ishii; K Hirota; K Makino; K Fukuda
        FREE RADICAL BIOLOGY AND MEDICINE, Feb. 2001, Peer-reviewed
      • Caspases mediate tumor necrosis factor-alpha-induced neutrophil apoptosis and downregulation of reactive oxygen production
        K Yamashita; A Takahashi; S Kobayashi; H Hirata; PW Mesner; SH Kaufmann; S Yonehara; K Yamamoto; T Uchiyama; M Sasada
        BLOOD, Jan. 1999, Peer-reviewed
      • The expression of co-stimulatory molecules and their relationship to the prognosis of human acute myeloid leukaemia: poor prognosis of B7-2-positive leukaemia
        A Maeda; K Yamamoto; K Yamashita; K Asagoe; M Nohgawa; K Kita; H Iwasaki; T Ueda; A Takahashi; M Sasada
        BRITISH JOURNAL OF HAEMATOLOGY, Sep. 1998, Peer-reviewed
      • Successful treatment with donor leukocyte transfusion followed by interferon-alpha in a patient with relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation
        A. Maeda; K. Yamamoto; Y. Kotone; K. Yamashita; N. Yoshinaga; H. Hirata; K. Asagoe; M. Nohgawa; A. Takahashi; H. Ohno; M. Tashima; M. Sasada
        [Rinshō ketsueki] The Japanese journal of clinical hematology, 1998, Peer-reviewed

      Misc.

      • Efficacy of Foscarnet in Preventing HHV6 Encephalitis in Adult Cord Blood Transplantation
        鈴木光太郎; 諫田淳也; 家村知樹; 新井康之; 渡邊瑞希; 島津裕; 北脇年雄; 水本智咲; 山下浩平; 高折晃史
        日本造血・免疫細胞療法学会総会プログラム・抄録集, 2024
      • 高濃度尿酸によるNADPH oxidase非依存性NETosisの誘導
        西中瑶子; 森田真紀子; 荒井俊之; 山下浩平; 足立壯一
        日本Cell Death学会学術集会プログラム抄録集, 2012
      • NETosisにおける一重項酸素の役割
        西中瑶子; 森田真紀子; 山下浩平; 荒井俊之; 足立壯一
        日本Cell Death学会学術集会プログラム抄録集, 2011
      • 細胞内で発生させた一重項酸素による細胞死に対するエダラボンの効果
        西中瑶子; 荒井俊之; 山下浩平; 足立壯一
        日本Cell Death学会学術集会プログラム抄録集, 2010
      • N-アセチルシステインの一重項酸素消去能と細胞死について
        西中瑶子; 荒井俊之; 三好隆史; 山下浩平; 足立壯一
        日本アポトーシス研究会学術集会プログラム要旨集, 2009
      • 移植に伴う感染症 同種造血幹細胞移植後に合併したHHV-6脳炎の6例
        齋藤 崇; 山下 浩平; 白野 倫徳; 松島 晶; 長尾 美紀; 藤原 尚子; 高倉 俊二; 伊藤 穣; 飯沼 由嗣; 一山 智
        感染症学雑誌, Sep. 2008
      • 移植に伴う感染症 同種造血細胞幹移植後に合併したHHV-6脳炎の6例
        齋藤 崇; 山下 浩平; 白野 倫徳; 松島 晶; 長尾 美紀; 藤原 尚子; 高倉 俊二; 伊藤 穣; 飯沼 由嗣; 一山 智
        感染症学雑誌, Mar. 2008
      • コリスチンの全身投与により軽快したメタロβラクタマーゼ産生緑膿菌感染症の1例
        斉藤 崇; 田嶌 政治; 山下 浩平; 樋口 武史; 白野 倫徳; 松島 晶; 長尾 美紀; 藤原 尚子; 高倉 俊二; 伊藤 穣; 田中 美智男; 飯沼 由嗣; 一山 智
        感染症学雑誌, Mar. 2007
      • MEFV gene mutation in two cases of pyoderma gangrenosum with aseptic arthritis
        Y. Honda; A. Otsuka; K. Yamashita; A. Takaori-Kondo; K. Kabashima
        JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, Dec. 2016
      • 炎症巣における好中球の機能制御 : イノシンの役割について
        伊藤 洋志; 山下 浩平; 山本 徹也; 笹田 昌孝
        痛風と核酸代謝 = Gout and nucleic acid metabolism, 01 Jul. 2007
      • 高尿酸血症の治療 (特集 プライマリ・ケア医のための高尿酸血症・痛風の診かた)
        笹田 昌孝; 山下 浩平
        治療, Nov. 2006
      • purines による好中球のO_2^-放出能と遊走能に対する修飾作用
        伊藤 洋志; 山下 浩平; 山本 徹也; 山本 孝吉; 笹田 昌孝
        痛風と核酸代謝 = Gout and nucleic acid metabolism, 01 Jun. 2005
      • 痛風発作の病態--好中球の役割
        笹田 昌孝; 山下 浩平
        京都大学医療技術短期大学部紀要, 2000
      • 成人白血病に対する臍帯血移植療法--非血縁者ドナー骨髄移植療法との比較検討
        山下 浩平; 一戸 辰夫
        内科, Nov. 2005
      • Reappraisal of bacterial prophylaxis in allogeneic marrow or peripheral blood stem cell transplantations after myeloablative conditionings
        J. Kanda; T. Ichinohe; T. Saito; K. Yamashita; T. Kondo; T. Ishikawa; S. Ichiyama; T. Uchiyama
        BONE MARROW TRANSPLANTATION, Mar. 2009
      • 好中球の遊走と活性酸素産生を制御する purine nucleosides の作用機序について
        伊藤 洋志; 山下 浩平; 山本 徹也; 笹田 昌孝
        痛風と核酸代謝 = Gout and nucleic acid metabolism, 01 Jul. 2006
      • 痛風発作と食細胞
        山下 浩平; 笹田 昌孝
        痛風と核酸代謝 = Gout and nucleic acid metabolism, 01 Dec. 2000
      • Characteristics and clinical significance of late-onset neutropenia after rituximab treatment
        新井 康之; 山下 浩平
        血液内科, Apr. 2014
      • X連鎖重症複合免疫不全症に合併したホジキン様EBV関連リンパ増殖性疾患の1例
        和田 典也; 中村 桃子; 近藤 忠一; 進藤 岳郎; 北脇 年雄; 菱澤 方勝; 山下 浩平; 高折 晃史; 井澤 和司; 八角 高裕
        臨床血液, Feb. 2020
      • EBV陽性の孤発性髄外形質細胞腫の1例
        河原 宏紀; 藤田 晴之; 菱澤 方勝; 山下 浩平; 高折 晃史; 坂中 克行
        臨床血液, Jan. 2019
      • Sphingolipid Pathway Regulates Innate Immune Responses at the Fetomaternal Interface during Pregnancy
        Kiyomi Mizugishi; Kouhei Yamashita
        FASEB JOURNAL, Apr. 2015
      • 多発性骨髄腫の画像診断 : FDG-PET, MET-PET (特集 多発性骨髄腫の病態と最新治療 : 基礎と臨床の最新情報) -- (診断と治療研究)
        小林 正行; 山下 浩平; 高折 晃史
        日本臨床, Jan. 2015
      • Presepsin ( soluble CD14 subtype) Is Secreted from Human Monocytes after Phagocytosis - in Vitro Analyses and a Retrospective Cohort Study in Patients with Allogeneic Stem Cell Transplantation
        Yasuyuki Arai; Kouhei Yamashita; Kiyomi Mizugishi; Akifumi Takaori-Kondo
        BLOOD, Dec. 2014
      • 消化管生検検体を用いた定量的PCR法による同種移植後サイトメガロウイルス胃腸炎の診断と早期治療介入の有用性
        新井 康之; 近藤 忠一; 北野 俊行; 菱澤 方勝; 山下 浩平; 門脇 則光; 高折 晃史
        臨床血液, Dec. 2014
      • ANTI-LACTOFERRIN AUTOANTIBODIES CONTRIBUTE TO THE PATHOGENESIS OF IGG4-RELATED DISEASE BY INDUCING NEUTROPHIL EXTRACELLULAR TRAP FORMATION
        Y. Arai; K. Yamashita; K. Mizugishi; A. Takaori-Kondo
        ANNALS OF THE RHEUMATIC DISEASES, Jun. 2014
      • Uric Acid Induces NADPH Oxidase-Independent Neutrophil Extracellular Trap Formation
        Yasuyuki Arai; Yoko Nishinaka; Toshiyuki Arai; Kiyomi Mizugishi; Souichi Adachi; Akifumi Takaori-Kondo; Kouhei Yamashita
        BLOOD, Nov. 2013
      • PLASMACYTOID DENDRITIC CELLS ACTIVATED BY NEUTROPHIL EXTRACELLULAR TRAPS CONTRIBUTE TO THE PATHOGENESIS OF IGG4-RELATED DISEASE
        Y. Arai; K. Yamashita; K. Mizugishi; A. Takaori-Kondo
        ANNALS OF THE RHEUMATIC DISEASES, Jun. 2013
      • Serum Neutrophil Extracellular Traps (NETs) Are a Potential Predictive Marker for Thrombotic Microangiopathy (TMA) After Allogeneic Stem Cell Transplantation
        Yasuyuki Arai; Soichiro Sakamoto; Kouhei Yamashita; Kiyomi Mizugishi; Toshiyuki Kitano; Tadakazu Kondo; Hiroshi Kawabata; Norimitsu Kadowaki; Akifumi Takaori-Kondo
        BLOOD, Nov. 2012
      • A novel role of uric acid in neutrophil extracellular trap formation
        NISHINAKA Yoko; ARAI Toshiyuki; MORITA Makiko; ARAI Yasuyuki; MIZUGISHI Kiyomi; ADACHI Souichi; TAKAORI‐KONDO Akifumi; YAMASHITA Kouhei
        臨床血液, 30 Sep. 2012
      • Recent advances in diagnostic imaging of multiple myeloma focusing on positron emission tomography
        西澤 正俊; 山下 浩平; 高折 晃史
        医学のあゆみ, 29 Sep. 2012
      • 発熱性好中球減少症の発症時に,敗血症性ショック発症の予測は可能か
        小西義延; 高倉俊二; 堀田剛; 山本正樹; 松村康史; 松島晶; 長尾美紀; 伊藤穣; 近藤忠一; 山下浩平; 高折晃史; 一山智
        感染症学雑誌, 20 Sep. 2012
      • 同種造血幹細胞移植におけるタクロリムス水和物徐放性カプセルの使用経験
        新井 康之; 近藤 忠一; 小林 正行; 山下 浩平; 一戸 辰夫; 門脇 則光; 石川 隆之; 高折 晃史
        日本造血細胞移植学会雑誌, Jul. 2012
      • 骨髄腫に対するフルダラビンを前処置に用いた同種造血幹細胞移植後の治療成績の検討
        MORI MINAKO; KONDO TADAKAZU; HISHISAWA MASAKATSU; NISHIKORI MOMOKO; MIURA YASUO; YAMASHITA KOHEI; ICHINOHE TATSUO; KADOWAKI NORIMITSU; TAKAORI AKIFUMI
        日本造血細胞移植学会総会プログラム・抄録集, 01 Feb. 2012
      • Activation of Toll-like Receptors and NOD-like Receptors Is Involved in Enhanced IgG4 Responses in Autoimmune Pancreatitis
        渡邉 智裕; 山下 浩平; 藤川 砂織
        細胞科学研究財団助成研究報告集, 2012
      • Singlet Oxygen Is Essential for Neutrophil Extracellular Trap Formation
        Yoko Nishinaka; Makiko Morita; Toshiyuki Arai; Souichi Adachi; Akifumi Takaori-Kondo; Kouhei Yamashita
        BLOOD, Nov. 2011
      • Singlet oxygen is essential for neutrophil extracellular trap formation
        YAMASHITA Kouhei; NISHINAKA Yoko; ARAI Toshiyuki; ADACHI Souichi; TAKAORI‐KONDO Akifumi
        臨床血液, 30 Sep. 2011
      • 免疫抑制剤中止後に発症した重症水痘帯状疱疹ウイルス感染症の3例
        上原晶子; 安間恵子; 吉本啓助; 山本正樹; 松村康史; 松島晶; 長尾美紀; 伊藤穣; 高倉俊二; 樋口武史; 田中美智男; 一山智; 山下浩平; 高折晃史
        感染症学雑誌, 20 Mar. 2011
      • 中枢神経原発悪性リンパ腫に対するBonnプロトコールの経験
        TADA KOHEI; KONDO TADAKAZU; NISHIKIORI MOMOKO; HISHIZAWA KAZUMASA; YAMASHITA KOHEI; ICHINOHE TATSUO; ISHIKAWA TAKAYUKI; UCHIYAMA SUGURU
        臨床血液, 30 Sep. 2009
      • 当院における成人T細胞白血病症例の後方視的解析
        内山 達樹; 菱澤 方勝; 諫田 淳也; 一戸 辰夫; 小林 正行; 錦織 桃子; 川端 浩; 門脇 則光; 高折 晃史; 山下 浩平; 近藤 忠一; 石川 隆之; 内山 卓
        臨床血液, Sep. 2009
      • 当科におけるミニ移植の成績
        近藤 忠一; 一戸 辰夫; 小林 正行; 菱澤 方勝; 錦織 桃子; 川端 浩; 門脇 則光; 高折 晃史; 山下 浩平; 石川 隆之; 内山 卓
        臨床血液, Sep. 2009
      • マントル細胞リンパ腫におけるR-Hyper CVAD療法
        島津 裕; 近藤 忠一; 石川 隆之; 内山 達樹; 坂本 宗一郎; 佐藤 貴之; 多田 浩平; 丸山 亙; 小林 正行; 錦織 桃子; 菱澤 方勝; 門脇 則光; 川端 浩; 高折 晃史; 山下 浩平; 一戸 辰夫; 内山 卓
        臨床血液, Sep. 2009
      • 急性前骨髄球性白血病のPETHEMAプロトコールによる治療成績
        坂本 宗一郎; 石川 隆之; 吉岡 聡; 菱澤 方勝; 錦織 桃子; 小林 正行; 近藤 忠一; 山下 浩平; 一戸 辰夫; 川端 浩; 高折 晃史; 門脇 則光; 内山 卓
        臨床血液, Sep. 2009
      • T細胞性リンパ腫症例における末梢血T細胞のPD‐1発現の意義
        YAMAMOTO REI; TAJIMA MASAHARU; NISHIKIORI MOMOKO; SAKAI TOMOMI; HISHIZAWA TAKAMASA; YAMASHITA KOHEI; KONDO TADAKAZU; OMORI KATSUYUKI; SUZUKI TAKAYO; UCHIYAMA TAKASHI
        臨床血液, 30 Sep. 2008
      • 当科における治療関連MDS/AML 22症例の解析
        藤田 晴之; 近藤 忠一; 山下 浩平; 菱澤 方勝; 錦織 桃子; 川端 浩; 一戸 辰夫; 高折 晃史; 門脇 則光; 石川 隆之; 内山 卓
        臨床血液, Sep. 2008
      • 臍帯血移植後にdonor cell leukemiaを発症した悪性リンパ腫の1例
        山本 和代; 近藤 忠一; 菱澤 方勝; 錦織 桃子; 山下 浩平; 一戸 辰夫; 川端 浩; 高折 晃史; 門脇 則光; 堀 利行; 石川 隆之; 内山 卓
        臨床血液, Sep. 2008
      • 緩和な前処置を用いた同種造血幹細胞移植後の造血器腫瘍再発例の予後に関する検討
        山内 達樹; 一戸 辰夫; 丸山 亙; 山本 和代; 石上 隆宏; 篠原 正信; 阪本 貴士; 藤田 晴之; 小林 正行; 錦織 桃子; 菱澤 方勝; 川端 浩; 門脇 則光; 高折 晃史; 堀 利行; 山下 浩平; 近藤 忠一; 石川 隆之; 内山 卓
        臨床血液, Sep. 2008
      • 単一施設における複数回同種移植に関する検討
        丸山 亙; 一戸 辰夫; 山本 和代; 石上 隆宏; 内山 達樹; 篠原 正信; 阪本 貴士; 藤田 晴之; 菱澤 方勝; 錦織 桃子; 山下 浩平; 近藤 忠一; 川端 浩; 高折 晃史; 門脇 則光; 堀 利行; 石川 隆之; 内山 卓
        臨床血液, Sep. 2008
      • 移植前血清フェリチン値が造血器腫瘍に対する同種造血幹細胞移植の成績に与える影響の検討
        水本 智咲; 諫田 淳也; 川端 浩; 一戸 辰夫; 菱澤 方勝; 錦織 桃子; 高折 晃史; 門脇 則光; 山下 浩平; 近藤 忠一; 石川 隆之; 内山 卓
        臨床血液, Sep. 2008
      • 当院における同種造血幹細胞移植後多発性筋炎の検討
        阪本 貴士; 一戸 辰夫; 篠原 正信; 島津 裕; 門脇 則光; 山下 浩平; 近藤 忠一; 石川 隆之; 内山 卓
        臨床血液, Sep. 2008
      • 非血縁者間骨髄移植後の非感染性肺合併症 緩和な前処置と従来型前処置の比較
        篠原 正信; 諫田 淳也; 一戸 辰夫; 丸山 亙; 山本 和代; 石上 隆宏; 内山 達樹; 阪本 貴士; 藤田 晴之; 小林 正行; 錦織 桃子; 菱澤 方勝; 川端 浩; 門脇 則光; 高折 晃史; 堀 利行; 山下 浩平; 近藤 忠一; 石川 隆之; 内山 卓
        臨床血液, Sep. 2008
      • 血液内科病棟におけるカルバペネム系抗菌剤使用制限
        石上隆宏; 斉藤崇; 石川隆之; 井尾克宏; 松井道志; 蝶名林和久; 一戸辰夫; 山下浩平; 近藤忠一; 一山智; 内山卓
        臨床血液, 30 Sep. 2007
      • 緩和な前処置を用いた同種造血幹細胞移植における幹細胞源としての骨髄と末梢血の比較
        松井 道志; 諫田 淳也; 一戸 辰夫; 井尾 克宏; 蝶名林 和久; 石上 隆宏; 菱澤 方勝; 錦織 桃子; 川端 浩; 山下 浩平; 近藤 忠一; 高折 晃史; 堀 利行; 門脇 則光; 石川 隆之; 内山 卓
        臨床血液, Sep. 2007
      • HTLV-I陰性成熟T/NK細胞腫瘍に対する同種造血幹細胞移植
        蝶名林 和久; 石川 隆之; 一戸 辰夫; 井尾 克宏; 石上 隆宏; 松井 道志; 鷹尾 珠美子; 近藤 忠一; 山下 浩平; 菱澤 方勝; 錦織 桃子; 川端 浩; 高折 晃史; 門脇 則光; 堀 利行; 内山 卓
        臨床血液, Sep. 2007
      • 急性骨髄性白血病・ハイリスク骨髄異形成症候群に対する同種造血幹細胞移植の成績に急性GVHDが与える影響
        井尾 克宏; 諌田 淳也; 一戸 辰夫; 松井 道志; 蝶名林 和久; 石上 隆宏; 菱澤 方勝; 錦織 桃子; 川端 浩; 山下 浩平; 近藤 忠一; 高折 晃史; 堀 利行; 門脇 則光; 石川 隆之; 内山 卓
        臨床血液, Sep. 2007
      • Effects of edaravone on singlet oxygen released from activated human neutrophils (vol 103, pg 117, 2007)
        Piyanart Sommani; Toshiyuki Arai; Kouhei Yamashita; Takashi Miyoshi; Hiroko Mori; Masataka Sasada; Keisuke Makino
        JOURNAL OF PHARMACOLOGICAL SCIENCES, Feb. 2007
      • T細胞性リンパ腫におけるEBER陽性率と臨床経過・予後についての検討
        田中 康博; 諌田 淳也; 水本 智咲; 田嶌 政治; 錦織 桃子; 山下 浩平; 近藤 忠一; 川端 浩; 一戸 辰夫; 高折 晃文; 門脇 則光; 堀 利行; 石川 隆之; 内山 卓; 橘 充弘; 羽賀 博典
        臨床血液, Sep. 2006
      • 非破壊的前処置を用いた非血縁者間同種血液幹細胞移植の検討
        三好 隆史; 石川 隆之; 山下 浩平; 近藤 忠一; 一戸 辰夫; 高折 晃史; 門脇 則光; 堀 利行; 内山 卓
        日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2005
      • B細胞リンパ腫に対するmelphalanとnitrosourea併用前処置による自家造血幹細胞移植の有効性
        笹田 亜麻子; 石川 隆之; 山下 浩平; 近藤 忠一; 一戸 辰夫; 高折 晃史; 門脇 則光; 堀 利行; 内山 卓
        日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2005
      • 成人T細胞白血病に対する同種造血幹細胞移植後の症候性サイトメガロウイルス感染症
        山本 玲; 石川 隆之; 三好 隆史; 吉岡 聡; 山下 浩平; 近藤 忠一; 一戸 辰夫; 高折 晃史; 門脇 則光; 堀 利行; 内山 卓
        日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2005
      • 血液分離菌より見た抗菌剤使用制限の効果
        吉岡 聡; 斉藤 崇; 山本 玲; 三好 隆史; 山下 浩平; 近藤 忠一; 一戸 辰夫; 高折 晃史; 門脇 則光; 石川 隆之; 堀 利行; 一山 智; 内山 卓
        日本血液学会・日本臨床血液学会総会プログラム・抄録集, Sep. 2005
      • 好中球の機能制御におけるプリン体 : 好中球の諸機能修飾作用
        伊藤 洋志; 平田 大二; 山下 浩平; 笹田 昌孝
        痛風と核酸代謝 = Gout and nucleic acid metabolism, 01 Jul. 2004
      • In vivo selective enhancement of correction of human X-linked chronic granulomatous disease neutrophils in NOD/SCID mice transplanted with CD34+stem cells transduced with a bicistronic gp91phox/benzyl guanine resistant methylguanine methyltransferase vector
        U Choi; K Yamashita; L Caldwell; HL Malech
        MOLECULAR THERAPY, May 2004
      • Severe chronic graft-versus-host-disease is characterized by an increase in CD4(+) effector memory cells relative to central memory cells that normalize following extracorporeal photopheresis.
        K Yamashita; U Choi; PC Woltz; M Tamari; K Castro; FT Hakim; SZ Pavletic; HL Malech; ME Horwitz
        BLOOD, Nov. 2003
      • Ex vivo generation of potent murine regulatory CD4 T-cells using TGF-beta.
        K Yamashita; GZ Song; DA Horwitz; HL Malech; ME Horwitz
        BLOOD, Nov. 2002
      • Dissection of caspase cascade in Fas-induced apoptosis.
        H Hirata; S Kobayashi; K Yamashita; T Okazaki; H Sawai; A Takahashi; K Yamamoto; T Uchiyama; M Sasada
        BLOOD, Nov. 1998

      External funds: others

      • 好中球細胞外トラップの炎症・免疫疾患における役割とその制御機構の解明
        平成23年度（第30回）血液医学研究分野一般研究助成金
        公益財団法人先進医薬研究振興財団
      • 免疫グロブリンによるオゾン産生の機序解析と殺菌作用への応用
        平成18年度（第8回）血液医学分野萌芽研究助成
        財団法人先進医薬研究振興財団　
      list
        Last Updated :2025/04/23

        Education

        Teaching subject(s)

        • From 01 Apr. 2024, To 31 Mar. 2025
          Advanced Cancer Nursing Lecture I
          M298, Spring, Graduate School of Medicine, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Cancer Nursing Lecture I
          M298, Spring, Graduate School of Medicine, 2
        • From Apr. 2011, To Mar. 2012
          生体防御学
          Fall, 医学部
        • From Apr. 2011, To Mar. 2012
          生体防御学概論
          Fall, 医学部
        • From Apr. 2011, To Mar. 2012
          生体防御看護学
          Fall, 医学部
        • From Apr. 2011, To Mar. 2012
          臨床基礎看護学Ⅱ
          Fall, 医学部
        • From Apr. 2012, To Mar. 2013
          The Outline of Host Defense
          Fall, 医学部
        • From Apr. 2012, To Mar. 2013
          The Outline of Host Defense
          Fall, 医学部
        • From Apr. 2012, To Mar. 2013
          Host defense & Infenction Control Nursing
          Fall, 医学部
        • From Apr. 2012, To Mar. 2013
          Clinical Principle of Nursing II
          Fall, 医学部
        • From Apr. 2013, To Mar. 2014
          The Outline of Host Defense
          Fall, 医学部（人間健康科学科）
        • From Apr. 2013, To Mar. 2014
          The Outline of Host Defense
          Fall, 医学部（人間健康科学科）
        • From Apr. 2014, To Mar. 2015
          The Outline of Host Defense
          Fall, 医学部（人間健康科学科）
        • From Apr. 2014, To Mar. 2015
          The Outline of Host Defense
          Fall, 医学部（人間健康科学科）
        • From Apr. 2015, To Mar. 2016
          The Outline of Host Defense
          Fall, 医学部（人間健康科学科）
        • From Apr. 2016, To Mar. 2017
          The Outline of Host Defense
          Fall, 医学部（人間健康科学科）
        • From Apr. 2017, To Mar. 2018
          The Outline of Host Defense
          Fall, 医学部（人間健康科学科）
        • From Apr. 2019, To Mar. 2020
          The Outline of Host Defense
          Spring, 医学部（人間健康科学科）
        • From Apr. 2020, To Mar. 2021
          The Outline of Host Defense
          Spring, 医学部（人間健康科学科）
        list
          Last Updated :2025/04/23

          Administration

          School management (title, position)

          • From 01 Apr. 2021, To 31 Mar. 2023
            組換えＤＮＡ実験安全委員会 委員

          Faculty management (title, position)

          • 安全衛生委員会
          • 研修医ワーキンググループ

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