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Handa, Tomohiro

Graduate School of Medicine Program-Specific Associate Professor

Handa, Tomohiro
list
    Last Updated :2023/01/25

    Basic Information

    Concurrent Affiliation

    • Graduate School of Medicine, 医学研究科 医学専攻

    Academic Degree

    • 博士(医学)(京都大学)

    ID,URL

    researchmap URL

    list
      Last Updated :2023/01/25

      Research

      Research Topics, Overview of the research

      • Research Topics

        Clinical and basic reserch of Interstitial lung diseases

      Papers

      • Can the Sarcoidosis Health Questionnaire predict the long-term outcomes in Japanese sarcoidosis patients?
        Kiminobu Tanizawa; Tomohiro Handa; Sonoko Nagai; Toru Oga; Takeshi Kubo; Yutaka Ito; Kensaku Aihara; Kohei Ikezoe; Akihiko Sokai; Yoshinari Nakatsuka; Toyohiro Hirai; Kazuo Chin; Michiaki Mishima; Takateru Izumi
        Respiratory medicine, Mar. 2019, Peer-reviewed
      • Serum matrix metalloproteinase levels in polymyositis/dermatomyositis patients with interstitial lung disease.
        Nakatsuka Y; Handa T; Nakashima R; Tanizawa K; Kubo T; Murase Y; Sokai A; Ikezoe K; Hosono Y; Watanabe K; Tokuda S; Uno K; Yoshizawa A; Tsuruyama T; Uozumi R; Nagai S; Hatta K; Taguchi Y; Mishima M; Chin K; Mimori T; Hirai T
        Rheumatology (Oxford)., 2019, Peer-reviewed
      • Nutrition-related factors associated with waiting list mortality in patients with interstitial lung disease: A retrospective cohort study.
        Oshima A; Nishimura A; Chen-Yoshikawa TF; Harashima SI; Komatsu T; Handa T; Aoyama A; Takahashi K; Ikeda M; Oshima Y; Ikezoe K; Sato S; Isomi M; Shide K; Date H; Inagaki N
        Clin Transplant., 2019, Peer-reviewed
      • The long-term outcome of interstitial lung disease with antiaminoacyl-tRNA synthetase antibodies
        Kiminobu Tanizawa; Tomohiro Handa; Ran Nakashima; Takeshi Kubo; Yuji Hosono; Kizuku Watanabe; Kensaku Aihara; Kohei Ikezoe; Akihiko Sokai; Yoshinari Nakatsuka; Yoshio Taguchi; Kazuhiro Hatta; Satoshi Noma; Yoichiro Kobashi; Akihiko Yoshizawa; Toru Oga; Toyohiro Hirai; Kazuo Chin; Sonoko Nagai; Takateru Izumi; Tsuneyo Mimori; Michiaki Mishima
        RESPIRATORY MEDICINE, Jun. 2017, Peer-reviewed
      • Outcomes of various transplant procedures (single, sparing, inverted) in living-donor lobar lung transplantation
        Hiroshi Date; Akihiro Aoyama; Kyoko Hijiya; Hideki Motoyama; Tomohiro Handa; Hideyuki Kinoshita; Shiro Baba; Toshiyuki Mizota; Kenji Minakata; Toyofumi F. Chen-Yoshikawa
        JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, Feb. 2017, Peer-reviewed
      • Comprehensive evaluation of airway involvement in pulmonary sarcoidosis
        Kiminobu Tanizawa; Tomohiro Handa; Sonoko Nagai; Akio Niimi; Tsuyoshi Oguma; Takeshi Kubo; Yutaka Ito; Kensaku Aihara; Kohei Ikezoe; Hisako Matsumoto; Toyohiro Hirai; Kazuo Chin; Michiaki Mishima
        ERJ Open Research, 01 Jan. 2017, Peer-reviewed
      • F-18-FDG Uptake in Less Affected Lung Field Provides Prognostic Stratification in Patients with Interstitial Lung Disease
        Tomomi Nobashi; Takeshi Kubo; Yuji Nakamoto; Tomohiro Handa; Sho Koyasu; Takayoshi Ishimori; Michiaki Mishima; Kaori Togashi
        JOURNAL OF NUCLEAR MEDICINE, Dec. 2016, Peer-reviewed
      • The utility of PET/CT with Ga-68-DOTATOC in sarcoidosis: comparison with Ga-67-scintigraphy
        Tomomi Nobashi; Yuji Nakamoto; Takeshi Kubo; Takayoshi Ishimori; Tomohiro Handa; Kiminobu Tanizawa; Kohei Sano; Michiaki Mishima; Kaori Togashi
        ANNALS OF NUCLEAR MEDICINE, Oct. 2016, Peer-reviewed
      • Microalbuminuria in Patients with Obstructive Sleep Apnea-Chronic Obstructive Pulmonary Disease Overlap Syndrome.
        Matsumoto T; Murase K; Tachikawa R; Minami T; Hamada S; Tanizawa K; Inouchi M; Handa T; Oga T; Yanagita M; Mishima M; Chin K
        Annals of the American Thoracic Society, Jun. 2016, Peer-reviewed
      • Role of mitochondrial hydrogen peroxide induced by intermittent hypoxia in airway epithelial wound repair in vitro
        Satoshi Hamada; Atsuyasu Sato; Mariko Hara-Chikuma; Hiroki Satooka; Koichi Hasegawa; Kazuya Tanimura; Kiminobu Tanizawa; Morito Inouchi; Tomohiro Handa; Toru Oga; Shigeo Muro; Michiaki Mishima; Kazuo Chin
        EXPERIMENTAL CELL RESEARCH, May 2016, Peer-reviewed
      • Aquaporin-3 potentiates allergic airway inflammation in ovalbumininduced murine asthma
        Kohei Ikezoe; Toru Oga; Tetsuya Honda; Mariko Hara-Chikuma; Xiaojun Ma; Tatsuaki Tsuruyama; Kazuko Uno; Jun-ichi Fuchikami; Kiminobu Tanizawa; Tomohiro Handa; Yoshio Taguchi; Alan S. Verkman; Shuh Narumiya; Michiaki Mishima; Kazuo Chin
        SCIENTIFIC REPORTS, May 2016, Peer-reviewed
      • Serial perfusion in native lungs in patients with idiopathic pulmonary fibrosis and other interstitial lung diseases after single lung transplantation
        Akihiko Sokai; Tomohiro Handa; Fengshi Chen; Kiminobu Tanizawa; Akihiro Aoyama; Takeshi Kubo; Kohei Ikezoe; Yoshinari Nakatsuka; Tsuyoshi Oguma; Toyohiro Hirai; Sonoko Nagai; Kazuo Chin; Hiroshi Date; Michiaki Mishima
        CLINICAL TRANSPLANTATION, Apr. 2016, Peer-reviewed
      • Two cases of autoimmune and secondary pulmonary alveolar proteinosis during immunosuppressive therapy in dermatomyositis with interstitial lung disease.
        Imura Y; Yukawa N; Handa T; Nakashima R; Murakami K; Yoshifuji H; Ohmura K; Ishii H; Nakata K; Mimori T
        Modern rheumatology, Mar. 2016, Peer-reviewed
      • PLATELET AGGREGABILITY IN PATIENTS WITH INTERSTITIAL PNEUMONIAS
        Tomohiro Handa; Kizuku Watanabe; Kiminobu Tanizawa; Toru Oga; Kensaku Aihara; Kohei Ikezoe; Akihiko Sokai; Yoshinari Nakatsuka; Toyohiro Hirai; Sonoko Nagai; Kazuo Chin; Hisanori Horiuchi; Michiaki Mishima
        SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, 2016, Peer-reviewed
      • Matrix metalloproteinase-10: a novel biomarker for idiopathic pulmonary fibrosis
        Akihiko Sokai; Tomohiro Handa; Kiminobu Tanizawa; Toru Oga; Kazuko Uno; Tatsuaki Tsuruyama; Takeshi Kubo; Kohei Ikezoe; Yoshinari Nakatsuka; Kazuya Tanimura; Shigeo Muro; Toyohiro Hirai; Sonoko Nagai; Kazuo Chin; Michiaki Mishima
        RESPIRATORY RESEARCH, Sep. 2015, Peer-reviewed
      • Bone mineral density in patients with idiopathic pulmonary fibrosis
        Kohei Ikezoe; Tomohiro Handa; Kiminobu Tanizawa; Takeshi Kubo; Tsuyoshi Oguma; Satoshi Hamada; Kizuku Watanabe; Kensaku Aihara; Akihiko Sokai; Yoshinari Nakatsuka; Shigeo Muro; Sonoko Nagai; Kazuko Uno; Kazuo Chin; Motonari Fukui; Toyohiro Hirai; Michiaki Mishima
        RESPIRATORY MEDICINE, Sep. 2015, Peer-reviewed
      • Clinical impact of high-attenuation and cystic areas on computed tomography in fibrotic idiopathic interstitial pneumonias
        Kiminobu Tanizawa; Tomohiro Handa; Sonoko Nagai; Toyohiro Hirai; Takeshi Kubo; Tsuyoshi Oguma; Isao Ito; Yutaka Ito; Kizuku Watanabe; Kensaku Aihara; Kohei Ikezoe; Toru Oga; Kazuo Chin; Takateru Izumi; Michiaki Mishima
        BMC PULMONARY MEDICINE, Jul. 2015, Peer-reviewed
      • Total lesion glycolysis as an IgG4-related disease activity marker
        Yoshinari Nakatsuka; Tomohiro Handa; Yuji Nakamoto; Tomomi Nobashi; Hajime Yoshihuji; Kiminobu Tanizawa; Kohei Ikezoe; Akihiko Sokai; Takeshi Kubo; Toyohiro Hirai; Kazuo Chin; Kaori Togashi; Tsuneyo Mimori; Michiaki Mishima
        MODERN RHEUMATOLOGY, Jul. 2015, Peer-reviewed
      • Living-donor lobar lung transplantation provides similar survival to cadaveric lung transplantation even for very ill patients
        Hiroshi Date; Masaaki Sato; Akihiro Aoyama; Tetsu Yamada; Toshiyuki Mizota; Hideyuki Kinoshita; Tomohiro Handa; Kiminobu Tanizawa; Kazuo Chin; Kenji Minakata; Fengshi Chen
        EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Jun. 2015, Peer-reviewed
      • A toll-like receptor 3 single nucleotide polymorphism in Japanese patients with sarcoidosis
        K. Ikezoe; T. Handa; K. Tanizawa; T. Kubo; I. Ito; A. Sokai; Y. Nakatsuka; S. Nagai; T. Izumi; M. Mishima
        TISSUE ANTIGENS, Mar. 2015, Peer-reviewed
      • Pleuroparenchymal fibroelastosis and non-specific interstitial pneumonia: frequent pulmonary sequelae of haematopoietic stem cell transplantation
        Yasuhide Takeuchi; Aya Miyagawa-Hayashino; Fengshi Chen; Takeshi Kubo; Tomohiro Handa; Hiroshi Date; Hironori Haga
        HISTOPATHOLOGY, Mar. 2015, Peer-reviewed
      • Impact of Obstructive Sleep Apnea on Abdominal Aortic Diameters
        Ryo Tachikawa; Satoshi Hamada; Masanori Azuma; Yoshiro Toyama; Kimihiko Murase; Kiminobu Tanizawa; Morito Inouchi; Tomohiro Handa; Toru Oga; Michiaki Mishima; Kazuo Chin
        AMERICAN JOURNAL OF CARDIOLOGY, Aug. 2014, Peer-reviewed
      • Neutrophil gelatinase-associated lipocalin in idiopathic pulmonary fibrosis
        Kohei Ikezoe; Tomohiro Handa; Kiyoshi Mori; Kizuku Watanabe; Kiminobu Tanizawa; Kensaku Aihara; Tatsuaki Tsuruyama; Aya Miyagawa-Hayashino; Akihiko Sokai; Takeshi Kubo; Shigeo Muro; Sonoko Nagai; Toyohiro Hirai; Kazuo Chin; Michiaki Mishima
        EUROPEAN RESPIRATORY JOURNAL, Jun. 2014, Peer-reviewed
      • The Multicenter Study of a New Assay for Simultaneous Detection of Multiple Anti-Aminoacyl-tRNA Synthetases in Myositis and Interstitial Pneumonia
        Ran Nakashima; Yoshitaka Imura; Yuji Hosono; Minae Seto; Akihiro Murakami; Kizuku Watanabe; Tomohiro Handa; Michiaki Mishima; Michito Hirakata; Tsutomu Takeuchi; Keishi Fujio; Kazuhiko Yamamoto; Hitoshi Kohsaka; Yoshinari Takasaki; Noriyuki Enomoto; Takafumi Suda; Kingo Chida; Shu Hisata; Toshihiro Nukiwa; Tsuneyo Mimori
        PLOS ONE, Jan. 2014, Peer-reviewed
      • Videothoracoscopy-assisted surgical lung biopsy for interstitial lung diseases
        M. Sonobe; T. Handa; K. Tanizawa; M. Sato; T. Sato; F. Chen; M. Omasa; T. Bando; H. Date; M. Mishima
        General Thoracic and Cardiovascular Surgery, 2014, Peer-reviewed
      • Treatment with Methotrexate and Low-dose Corticosteroids in Sarcoidosis Patients with Cardiac Lesions
        Sonoko Nagai; Takafumi Yokomatsu; Kiminobu Tanizawa; Kohei Ikezoe; Tomohiro Handa; Yutaka Ito; Shunpei Ogino; Takateru Izumi
        INTERNAL MEDICINE, 2014, Peer-reviewed
      • Clinical features of three cases with pulmonary alveolar proteinosis secondary to myelodysplastic syndrome developed during the course of Behçet's disease
        Tomohiro Handa; Takeshi Nakatsue; Motoo Baba; Toshinori Takada; Koh Nakata; Haruyuki Ishii
        Respiratory Investigation, Jan. 2014, Peer-reviewed
      • BMPR2 gene mutation in pulmonary arteriovenous malformation and pulmonary hypertension: A case report
        Tomohiro Handa; Yoshiaki Okano; Norifumi Nakanishi; Takayuki Morisaki; Hiroko Morisaki; Michiaki Mishima
        Respiratory Investigation, 2014, Peer-reviewed
      • Predictive factors for reintubation following noninvasive ventilation in patients with respiratory complications after living donor liver transplantation
        Yuichi Chihara; Hiroto Egawa; Toru Oga; Tomomasa Tsuboi; Tomohiro Handa; Shintaro Yagi; Taku Iida; Atsushi Yoshizawa; Kazuhiko Yamamoto; Michiaki Mishima; Koichi Tanaka; Shinji Uemoto; Kazuo Chin
        PLoS ONE, 05 Dec. 2013, Peer-reviewed
      • Interferon regulatory factor 5 polymorphisms in sarcoidosis
        Kiminobu Tanizawa; Tomohiro Handa; Sonoko Nagai; Hiroe Sato; Ryo Yamada; Isao Ito; Takeshi Kubo; Yutaka Ito; Kizuku Watanabe; Kensaku Aihara; Kohei Ikezoe; Michiaki Mishima; Takateru Izumi
        MODERN RHEUMATOLOGY, Nov. 2013, Peer-reviewed
      • Clinical Relevance of Plasma Prostaglandin F-2 alpha Metabolite Concentrations in Patients with Idiopathic Pulmonary Fibrosis
        Kensaku Aihara; Tomohiro Handa; Toru Oga; Kizuku Watanabe; Kiminobu Tanizawa; Kohei Ikezoe; Yoshio Taguchi; Hiroe Sato; Kazuo Chin; Sonoko Nagai; Shuh Narumiya; Athol U. Wells; Michiaki Mishima
        PLOS ONE, Jun. 2013, Peer-reviewed
      • Measurement of dyspnea in patients with obstructive sleep apnea
        Kensaku Aihara; Toru Oga; Chikara Yoshimura; Takefumi Hitomi; Yuichi Chihara; Yuka Harada; Kimihiko Murase; Yoshiro Toyama; Kiminobu Tanizawa; Tomohiro Handa; Tomomasa Tsuboi; Michiaki Mishima; Kazuo Chin
        SLEEP AND BREATHING, May 2013, Peer-reviewed
      • Analysis of systemic and airway inflammation in obstructive sleep apnea
        Kensaku Aihara; Toru Oga; Yuichi Chihara; Yuka Harada; Kiminobu Tanizawa; Tomohiro Handa; Takefumi Hitomi; Kazuko Uno; Michiaki Mishima; Kazuo Chin
        SLEEP AND BREATHING, May 2013, Peer-reviewed
      • The prognostic value of HRCT in myositis-associated interstitial lung disease
        Kiminobu Tanizawa; Tomohiro Handa; Ran Nakashima; Takeshi Kubo; Yuji Hosono; Kensaku Aihara; Kohei Ikezoe; Kizuku Watanabe; Yoshio Taguchi; Kazuhiro Hatta; Toru Oga; Kazuo Chin; Sonoko Nagai; Tsuneyo Mimori; Michiaki Mishima
        Respiratory Medicine, May 2013, Peer-reviewed
      • Analysis of systemic and airway inflammation in obstructive sleep apnea
        Kensaku Aihara; Toru Oga; Yuichi Chihara; Yuka Harada; Kiminobu Tanizawa; Tomohiro Handa; Takefumi Hitomi; Kazuko Uno; Michiaki Mishima; Kazuo Chin
        SLEEP AND BREATHING, May 2013, Peer-reviewed
      • Measurement of dyspnea in patients with obstructive sleep apnea
        Kensaku Aihara; Toru Oga; Chikara Yoshimura; Takefumi Hitomi; Yuichi Chihara; Yuka Harada; Kimihiko Murase; Yoshiro Toyama; Kiminobu Tanizawa; Tomohiro Handa; Tomomasa Tsuboi; Michiaki Mishima; Kazuo Chin
        SLEEP AND BREATHING, May 2013, Peer-reviewed
      • Flexible Positive Airway Pressure Improves Treatment Adherence Compared with Auto-adjusting PAP
        Yuichi Chihara; Tomomasa Tsuboi; Takefumi Hitomi; Masanori Azuma; Kimihiko Murase; Yoshiro Toyama; Yuka Harada; Kensaku Aihara; Kiminobu Tanizawa; Tomohiro Handa; Chikara Yoshimura; Toru Oga; Kazuhiko Yamamoto; Michiaki Mishima; Kazuo Chin
        SLEEP, Feb. 2013, Peer-reviewed
      • Impaired endothelium-dependent vasodilator response in patients with pulmonary fibrosis
        Kensaku Aihara; Tomohiro Handa; Sonoko Nagai; Kiminobu Tanizawa; Kohei Ikezoe; Kizuku Watanabe; Yuichi Chihara; Yuka Harada; Chikara Yoshimura; Toru Oga; Neiko Ozasa; Kazuko Uno; Kazuo Chin; Michiaki Mishima
        RESPIRATORY MEDICINE, Feb. 2013, Peer-reviewed
      • Association between Plasma Neutrophil Gelatinase Associated Lipocalin Level and Obstructive Sleep Apnea or Nocturnal Intermittent Hypoxia
        Kimihiko Murase; Kiyoshi Mori; Chikara Yoshimura; Kensaku Aihara; Yuichi Chihara; Masanori Azuma; Yuka Harada; Yoshiro Toyama; Kiminobu Tanizawa; Tomohiro Handa; Takefumi Hitomi; Toru Oga; Michiaki Mishima; Kazuo Chin
        PLoS ONE, 14 Jan. 2013, Peer-reviewed
      • Interstitial pneumonias associated with anti-ARS antibody and anti-CADM antibody
        T. Handa
        Japanese Journal of Chest Diseases, 2013, Peer-reviewed
      • Pulmonary hypertension in sarcoidosis
        T. Handa; S. Nagaj
        Japanese Journal of Chest Diseases, 2013, Peer-reviewed
      • Prognostic Significance of Preexisting Interstitial Lung Disease in Japanese Patients With Small-Cell Lung Cancer
        Yosuke Togashi; Katsuhiro Masago; Tomohiro Handa; Kiminobu Tanizawa; Chiyuki Okuda; Yuichi Sakamori; Hiroki Nagai; Young Hak Kim; Michiaki Mishima
        CLINICAL LUNG CANCER, Jul. 2012, Peer-reviewed
      • Analysis of anatomical and functional determinants of obstructive sleep apnea
        Kensaku Aihara; Toru Oga; Yuka Harada; Yuichi Chihara; Tomohiro Handa; Kiminobu Tanizawa; Kizuku Watanabe; Takefumi Hitomi; Tomomasa Tsuboi; Michiaki Mishima; Kazuo Chin
        SLEEP AND BREATHING, Jun. 2012, Peer-reviewed
      • Analysis of anatomical and functional determinants of obstructive sleep apnea
        Kensaku Aihara; Toru Oga; Yuka Harada; Yuichi Chihara; Tomohiro Handa; Kiminobu Tanizawa; Kizuku Watanabe; Takefumi Hitomi; Tomomasa Tsuboi; Michiaki Mishima; Kazuo Chin
        SLEEP AND BREATHING, Jun. 2012, Peer-reviewed
      • Impact of nasal continuous positive airway pressure for congenital adrenal hyperplasia with obstructive sleep apnea and bruxism
        Satoshi Hamada; Kazuo Chin; Takefumi Hitomi; Toru Oga; Tomohiro Handa; Tomomasa Tuboi; Akio Niimi; Michiaki Mishima
        SLEEP AND BREATHING, Mar. 2012, Peer-reviewed
      • Predictors of 5-year mortality in pulmonary Mycobacterium avium-intracellulare complex disease
        Y. Ito; T. Hirai; K. Maekawa; K. Fujita; S. Imai; S. Tatsumi; T. Handa; H. Matsumoto; S. Muro; A. Niimi; M. Mishima
        INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Mar. 2012, Peer-reviewed
      • Predictors of 5-year mortality in pulmonary Mycobacterium avium-intracellulare complex disease
        Y. Ito; T. Hirai; K. Maekawa; K. Fujita; S. Imai; S. Tatsumi; T. Handa; H. Matsumoto; S. Muro; A. Niimi; M. Mishima
        INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Mar. 2012, Peer-reviewed
      • Sarcoidosis Complicated with Major Pulmonary Artery Obstruction and Stenosis
        Koichi Hasegawa; Seiko Ohno; Mai Takada; Hiroshi Ogino; Shinsuke Shiotsu; Chieko Takumi; Noriya Hiraoka; Tomohiro Handa; Sonoko Nagai
        INTERNAL MEDICINE, 2012, Peer-reviewed
      • ENDPOINTS FOR CLINICAL TRIALS OF SARCOIDOSIS
        R. P. Baughman; M. Drent; D. A. Culver; J. C. Grutters; T. Handa; M. Humbert; M. A. Judson; E. E. Lower; J. Mana; C. A. Pereira; A. Prasse; R. Sulica; D. Valyere; V. Vucinic; A. U. Wells
        SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, 2012, Peer-reviewed
      • A CD40 single-nucleotide polymorphism affects the lymphocyte profiles in the bronchoalveolar lavage of Japanese patients with sarcoidosis
        K. Tanizawa; T. Handa; S. Nagai; I. Ito; T. Kubo; Y. Ito; K. Watanabe; K. Aihara; M. Mishima; T. Izumi
        TISSUE ANTIGENS, Dec. 2011, Peer-reviewed
      • HRCT features of interstitial lung disease in dermatomyositis with anti-CADM-140 antibody
        Kiminobu Tanizawa; Tomohiro Handa; Ran Nakashima; Takeshi Kubo; Yuji Hosono; Kizuku Watanabe; Kensaku Aihara; Toru Oga; Kazuo Chin; Sonoko Nagai; Tsuneyo Mimori; Michiaki Mishima
        RESPIRATORY MEDICINE, Sep. 2011, Peer-reviewed
      • Detection of antisynthetase syndrome in patients with idiopathic interstitial pneumonias
        Kizuku Watanabe; Tomohiro Handa; Kiminobu Tanizawa; Yuji Hosono; Yoshio Taguchi; Satoshi Noma; Yoichiro Kobashi; Takeshi Kubo; Kensaku Aihara; Kazuo Chin; Sonoko Nagai; Tsuneyo Mimori; Michiaki Mishima
        RESPIRATORY MEDICINE, Aug. 2011, Peer-reviewed
      • Comparison of biomarkers of subclinical lung injury in obstructive sleep apnea
        Kensaku Aihara; Toru Oga; Yuka Harada; Yuichi Chihara; Tomohiro Handa; Kiminobu Tanizawa; Kizuku Watanabe; Tomomasa Tsuboi; Takefumi Hitomi; Michiaki Mishima; Kazuo Chin
        RESPIRATORY MEDICINE, Jun. 2011, Peer-reviewed
      • Validation of the japanese version of the sarcoidosis health questionnaire: A cross-sectional study
        Kiminobu Tanizawa; Tomohiro Handa; Sonoko Nagai; Toru Oga; Takeshi Kubo; Yutaka Ito; Kizuku Watanabe; Kensaku Aihara; Kazuo Chin; Michiaki Mishima; Takateru Izumi
        HEALTH AND QUALITY OF LIFE OUTCOMES, May 2011, Peer-reviewed
      • Eosinophils and macrophages are involved in nitrosative stress in chronic eosinophilic pneumonia
        Hitoshi Nakaji; Hisako Matsumoto; Akio Niimi; Tomohiro Handa; Isao Ito; Makiko Kanai; Hisako Tabata; Hiroaki Sakai; Yoichiro Kobashi; Yoshiro Mochizuki; Kazuo Chin; Michiaki Mishima
        NITRIC OXIDE-BIOLOGY AND CHEMISTRY, May 2011, Peer-reviewed
      • Immediate Noninvasive Ventilation May Improve Mortality in Patients With Hepatopulmonary Syndrome After Liver Transplantation
        Yuichi Chihara; Hiroto Egawa; Tomomasa Tsuboi; Toru Oga; Tomohiro Handa; Kazuhiko Yamamoto; Michiaki Mishima; Koichi Tanaka; Shinji Uemoto; Kazuo Chin
        LIVER TRANSPLANTATION, Feb. 2011, Peer-reviewed
      • Long-term Changes in Airway-Wall Thickness on Computed Tomography in Asthmatic Patients
        H. Matsumoto; A. Niimi; M. Takemura; T. Ueda; M. Yamaguchi; H. Matsuoka; M. Jinnai; T. Takeda; K. Otsuka; T. Oguma; T. Handa; T. Hirai; K. Chin; M. Mishima
        JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY, 2011, Peer-reviewed
      • Efficacy of Blood-Patch Pleurodesis for Secondary Spontaneous Pneumothorax in Interstitial Lung Disease
        Kensaku Aihara; Tomohiro Handa; Sonoko Nagai; Kiminobu Tanizawa; Kizuku Watanabe; Yuka Harada; Yuichi Chihara; Takefumi Hitomi; Toru Oga; Tomomasa Tsuboi; Kazuo Chin; Michiaki Mishima
        INTERNAL MEDICINE, 2011, Peer-reviewed
      • To Authors Reply: Invasive Mechanical Ventilation in Patients with Idiopathic Pulmonary Fibrosis or Idiopathic Non-Specific Interstitial Pneumonia
        Keisuke Tomii; Ryo Tachikawa; Kazuo Chin; Kimihiko Murase; Tomohiro Handa; Michiaki Mishima; Kyosuke Ishihara
        INTERNAL MEDICINE, 2011, Peer-reviewed
      • Efficacy of Blood-Patch Pleurodesis for Secondary Spontaneous Pneumothorax in Interstitial Lung Disease
        Kensaku Aihara; Tomohiro Handa; Sonoko Nagai; Kiminobu Tanizawa; Kizuku Watanabe; Yuka Harada; Yuichi Chihara; Takefumi Hitomi; Toru Oga; Tomomasa Tsuboi; Kazuo Chin; Michiaki Mishima
        INTERNAL MEDICINE, 2011, Peer-reviewed
      • Importance of the PaCO2 from 3 to 6 months after initiation of long-term non-invasive ventilation
        Tomomasa Tsuboi; Motoharu Ohi; Toru Oga; Kazuko Machida; Yuichi Chihara; Yuka Harada; Kenichi Takahashi; Kensuke Sumi; Tomohiro Handa; Akio Niimi; Michiaki Mishima; Kazuo Chin
        RESPIRATORY MEDICINE, Dec. 2010, Peer-reviewed
      • Long-term nasal continuous positive airway pressure treatment lowers blood pressure in patients with obstructive sleep apnea regardless of age
        Kensaku Aihara; Kazuo Chin; Toru Oga; Ken-ichi Takahashi; Takefumi Hitomi; Misa Takegami; Tomohiro Handa; Akio Niimi; Tomomasa Tsuboi; Michiaki Mishima
        HYPERTENSION RESEARCH, Oct. 2010, Peer-reviewed
      • SIGNIFICANCE OF PLASMA NT-PROBNP LEVELS AS A BIOMARKER IN THE ASSESSMENT OF CARDIAC INVOLVEMENT AND PULMONARY HYPERTENSION IN PATIENTS WITH SARCOIDOSIS
        T. Handa; S. Nagai; S. Ueda; K. Chin; Y. Ito; K. Watanabe; K. Tanizawa; M. Tamaya; M. Mishima; T. Izumi
        SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, Jul. 2010, Peer-reviewed
      • CD24 GENE EXON 2 DIMORPHISM DOES NOT AFFECT DISEASE SUSCEPTIBILITY IN JAPANESE SARCOIDOSIS PATIENTS
        K. Tanizawa; T. Handa; S. Nagai; Y. Ito; K. Watanabe; K. Aihara; T. Izumi; M. Mishima
        SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, Jul. 2010, Peer-reviewed
      • Avoidance of Reintubation by Using Sedation during Noninvasive Positive Pressure Ventilation in a 3-Month-Old Infant with Postoperative Respiratory Failure
        Kizuku Watanabe; Kazuo Chin; Kenichi Takahashi; Masaya Murata; Hiraku Doi; Tomohiro Handa; Toru Oga; Tomomasa Tsuboi; Tadashi Ikeda; Tatsutoshi Nakahata; Ryuzo Sakata; Michiaki Mishima
        INTERNAL MEDICINE, 2010, Peer-reviewed
      • Noninvasive Ventilation Improves the Outcome of Pulmonary Complications after Liver Resection
        Masato Narita; Kiminobu Tanizawa; Kazuo Chin; Iwao Ikai; Tomohiro Handa; Toru Oga; Akio Niimi; Tomomasa Tsuboi; Michiaki Mishima; Shinji Uemoto; Etsuro Hatano
        INTERNAL MEDICINE, 2010, Peer-reviewed
      • Role of Non-invasive Ventilation in Managing Life-threatening Acute Exacerbation of Interstitial Pneumonia
        Keisuke Tomii; Ryo Tachikawa; Kazuo Chin; Kimihiko Murase; Tomohiro Handa; Michiaki Mishima; Kyosuke Ishihara
        INTERNAL MEDICINE, 2010, Peer-reviewed
      • Effects of Obstructive Sleep Apnea with Intermittent Hypoxia on Platelet Aggregability
        Toru Oga; Kazuo Chin; Arata Tabuchi; Kensuke Sumi; Kenichi Takahashi; Tomohiro Handa; Kanako Takahashi; Ryoji Taniguchi; Hirokazu Kondo; Mitsunori Kawato; Takeshi Morimoto; Michiaki Mishima; Toru Kita; Hisanori Horiuchi
        JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, Dec. 2009, Peer-reviewed
      • LONG-TERM COMPLICATIONS AND PROGNOSIS OF CHRONIC BERYLLIUM DISEASE
        T. Handa; S. Nagai; M. Kitaichi; K. Chin; Y. Ito; T. Oga; K. Takahashi; K. Watanabe; M. Mishima; T. Izumi
        SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, Jul. 2009, Peer-reviewed
      • Clinical and radiographic features of lung involvements in primary Sjögren syndrome
        T. Handa; I. Ito; S. Nagai
        Japanese Journal of Chest Diseases, 2009, Peer-reviewed
      • Computed Tomography Analysis of Airway Dimensions and Lung Density in Patients with Sarcoidosis
        Tomohiro Handa; Sonoko Nagai; Toyohiro Hirai; Kazuo Chin; Takeshi Kubo; Toru Oga; Akio Niimi; Hisako Matsumoto; Yutaka Ito; Kenichi Takahashi; Kizuku Watanabe; Takateru Izumi; Michiaki Mishima
        RESPIRATION, 2009, Peer-reviewed
      • Outcome of sarcoidosis
        Sonoko Nagai; Tomohiro Handa; Yutaka Ito; Kousuke Ohta; Manabu Tamaya; Takateru Izumi
        CLINICS IN CHEST MEDICINE, Sep. 2008, Peer-reviewed
      • Pharmacotherapy in patients with idiopathic pulmonary fibrosis
        S. Nagai; T. Handa; D. S. Kim
        Expert Opinion on Pharmacotherapy, Aug. 2008, Peer-reviewed
      • Bronchoalveolar lavage in idiopathic interstitial lung diseases
        Sonoko Nagai; Tomohiro Handa; Yutaka Ito; Minoru Takeuchi; Takateru Izumi
        SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, Oct. 2007, Peer-reviewed
      • HLA-DQB1*0602 allele is associated with splenomegaly in Japanese sarcoidosis
        H. Sato; S. Nagai; R. M. du Bois; T. Handa; Y. Suginoshita; K. Ohta; K. I. Welsh; T. Izumi
        JOURNAL OF INTERNAL MEDICINE, Oct. 2007, Peer-reviewed
      • Significance of pulmonary arterial pressure and diffusion capacity of the lung as prognosticator in patients with idiopathic pulmonary fibrosis
        Kunio Hamada; Sonoko Nagai; Shigeru Tanaka; Tomohiro Handa; Michio Shigematsau; Taishi Nagao; Michiaki Mishima; Masanori Kitaichi; Takateru Izumi
        CHEST, Mar. 2007, Peer-reviewed
      • Incidence of pulmonary hypertension and its clinical relevance in patients with interstitial pneumonias: Comparison between idiopathic and collagen vascular disease associated interstitial pneumonias
        Tomohiro Handa; Sonoko Nagai; Shinji Miki; Seigen Ueda; Naoichiro Yukawa; Yasutaka Fushimi; Yutaka Ito; Kosuke Ohta; Tsuneyo Mimori; Michiaki Mishima; Takateru Izumi
        INTERNAL MEDICINE, 2007, Peer-reviewed
      • Clinical and radiographic indices associated with airflow limitation in patients with sarcoidosis
        Tomohiro Handa; Sonoko Nagai; Yasataka Fushimi; Shinji Miki; Kosake Ohta; Akio Niimi
        CHEST, Dec. 2006, Peer-reviewed
      • Incidence of pulmonary hypertension and its clinical relevance in patients with sarcoidosis
        T Handa; S Nagai; S Miki; Y Fushimi; K Ohta; M Mishima; T Izumi
        CHEST, May 2006, Peer-reviewed
      • Multiple bone fractures found in a young sarcoidosis patient with long stable disease
        Tomohiro Handa; Sonoko Nagai; Isao Ito; Michio Shigematsu; Kunio Hamada; Masanori Kitaichi; Kosuke Ohta; Takateru Izumi; Michiaki Mishima
        Internal Medicine, 17 Jan. 2006, Peer-reviewed
      • Significance of BALF findings for diagnosis of diffuse lung diseases
        S. Nagai; T. Handa
        Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2006, Peer-reviewed
      • Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema
        Ito, I; S Nagai; T Handa; S Muro; T Hirai; M Tsukino; M Mishima
        AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Dec. 2005, Peer-reviewed
      • Patient characteristics and clinical features of Japanese sarcoidosis patients with low bronchoalveolar lavage CD4/CD8 ratios
        T Handa; S Nagai; M Shigematsu; RP Tabuena; M Takeuchi; T Mikuniya; K Hamada; T Izumi; M Mishima
        SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, Jun. 2005, Peer-reviewed
      • Long-term clinical course of a patient with anti PL-12 antibody accompanied by interstitial pneumonia and severe pulmonary hypertension
        T Handa; S Nagai; D Kawabata; T Nagao; M Takemura; M Kitaichi; T Izumi; T Mimori; M Mishima
        INTERNAL MEDICINE, Apr. 2005, Peer-reviewed
      • Pulmonary manifestations of primary Sjogren's syndrome
        Ito, I; S Nagai; M Kitaichi; AG Nicholson; T Johkoh; S Noma; DS Kim; T Handa; T Izumi; M Mishima
        AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Mar. 2005, Peer-reviewed
      • Sarcoidosis--immunological features and clinical issues
        T. Handa; S. Nagai; K. Ohta
        Nippon rinsho. Japanese journal of clinical medicine, 2005, Peer-reviewed
      • Pulmonary manifestations of primary Sjogren's syndrome: a clinical, radiologic, and pathologic study.
        tIto I; Nagai S; Kitaichi M; Nicholson AG; Johkoh T; Noma S; Kim DS; Handa T; Izumi T; Mishima M
        Am J Respir Crit Care Med., 2005, Peer-reviewed
      • Polymorphisms of B7 (CD80 and CD86) genes do not affect disease susceptibility to sarcoidosis
        T Handa; S Nagai; Ito, I; R Tabuena; M Shigematsu; K Hamada; M Kitaichi; T Izumi; T Aoyama; J Toguchida; M Mishima
        RESPIRATION, 2005, Peer-reviewed
      • Cell profiles of bronchoalveolar lavage fluid as prognosticators of idiopathic pulmonary fibrosis/usual interstitial pneumonia among Japanese patients
        RP Tabuena; S Nagai; T Tsutsumi; T Handa; T Minoru; T Mikuniya; M Shigematsu; K Hamada; T Izumi; M Mishima
        RESPIRATION, 2005, Peer-reviewed
      • Nonspecific interstitial pneumonia: a real clinical entity?
        S Nagai; T Handa; R Tabuena; M Kitaichi; T Izumi
        CLINICS IN CHEST MEDICINE, Dec. 2004, Peer-reviewed
      • Diabetes insipidius from neurosarcoidosis: Long-term follow-up for more than eight years
        RP Tabuena; S Nagai; T Handa; M Shigematsu; K Hamada; Ito, I; T Izumi; M Mishima; OP Sharma
        INTERNAL MEDICINE, Oct. 2004, Peer-reviewed
      • Cytotoxic T-lymphocyte antigen-4 (CTLA-4) exon 1 polymorphism affects lymphocyte profiles in bronchoalveolar lavage of patients with sarcoidosis
        T Handa; S Nagai; Ito, I; M Shigematsu; K Hamada; M Kitaichi; T Izumi; M Mishima
        SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, Oct. 2003, Peer-reviewed
      • Glomerulonephritis induced by methicillin-sensitive Staphylococcus aureus infection
        Tomohiro Handa; Takahiko Ono; Hitomi Watanabe; Toshiya Takeda; Eri Muso; Toru Kita
        Clinical and Experimental Nephrology, Sep. 2003, Peer-reviewed
      • Sarcoidosis with bilateral epididymal and testicular lesions
        T Handa; S Nagai; K Hamada; Ito, I; Y Hoshino; M Shigematsu; T Izumi; M Mishima
        INTERNAL MEDICINE, Jan. 2003, Peer-reviewed

      Awards

      • 2005
        京都医師会, 京都医師会臨床医会 学術奨励賞銅賞
      • 02 Nov. 2014
        Japan Society of Sarcoidosis and other Granulomatous disorders, 千葉保之・本間日臣記念賞

      External funds: Kakenhi

      • 生体肺移植におけるドナー、レシピエントの末梢血テロメア長と慢性移植肺機能不全
        Grant-in-Aid for Scientific Research (C)
        Basic Section 55010:General surgery and pediatric surgery-related
        Kyoto University
        半田 知宏
        From 01 Apr. 2020, To 31 Mar. 2023, Granted
        遺伝子多型;肺移植;慢性移植肺機能不全;アンギオテンシン転換酵素;テロメア;慢性拒絶
      • Multicenter study for peripheral blood telomere length in patients with idiopathic pulmonary fibrosis
        Grant-in-Aid for Scientific Research (C)
        Kyoto University
        Tomohiro Handa
        From 01 Apr. 2017, To 31 Mar. 2020, Project Closed
        特発性肺線維症;遺伝子変異;テロメア;ゲノム;老化;遺伝子;内科
      • Significance of sarcopenia in chronic respiratory diseases
        Grant-in-Aid for Scientific Research (C)
        Kyoto University
        Kiminobu Tanizawa
        From 01 Apr. 2016, To 31 Mar. 2019, Project Closed
        サルコペニア;慢性呼吸不全;間質性肺疾患;睡眠時無呼吸症候群;移植・再生医療;内科;臨床
      • Application of iPS cell technology to lung regeneration and development of bioresource for elucidating the mechanisms of lung diseases
        Grant-in-Aid for Scientific Research (A)
        Kyoto University
        Mishima Michiaki
        From 01 Apr. 2015, To 31 Mar. 2018, Project Closed
        分子細胞呼吸学;iPS細胞;肺臓器再生;疾患モデリング;分子細胞呼吸器学
      • Transcriptome analysis of pulmonary arterioles in interstitial pneumonia with pulmonary hypertension
        Grant-in-Aid for Scientific Research (C)
        Kyoto University
        Tomohiro Handa
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        間質性肺疾患;肺高血圧症;メトリックスメタロプロテアーゼ;マトリックスメタロプロテアーゼ;間質性肺炎;マイクロアレイ
      • Double-face culture system for application of alveolar epithelial cells induced from human iPS cells
        Grant-in-Aid for Scientific Research (B)
        Kyoto University
        Ito Isao
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        iPS細胞;肺胞上皮細胞;気道上皮細胞;肺前駆細胞;ナノファイバー;呼吸器疾患;肺気腫;再生医学;線毛上皮細胞;血管内皮細胞;ES細胞;nanofiber;microfluidics
      • Researches using iPS cells on intractable respiratory diseases to elucidate their pathogenesis and develop novel therapy.
        Grant-in-Aid for Scientific Research (A)
        Kyoto University
        MICHIAKI MISHIMA
        From 01 Apr. 2010, To 31 Mar. 2015, Project Closed
        iPS細胞;ES細胞;II型肺胞上皮細胞;surfactant protein C;carboxypeptidase M;3次元培養;Hermansky-Pudlak 症候群;嚢胞性線維症;疾患特異iPS;肺胞上皮細胞;特発性間質性肺炎;若年性肺気腫;リンパ脈管筋腫症;疾患特異的iPS;I型肺胞上皮細胞;分化誘導;Birt-Hogg-Dube症候群

      External funds: others

      • 難治性疾患政策研究事業 (2021年度分)
        厚生労働省, 厚生労働科学研究費補助金
        From 01 Apr. 2021, To 31 Mar. 2022
        分担
      • 特発性間質性肺炎における気管支肺胞洗浄液のトランスクリプトーム解析
        公益信託加藤記念難病研究助成基金
        From 2011, To 2012
        半田知宏
      • (2020度分)
        難治性疾患政策研究事業
        From 01 Apr. 2020, To 31 Mar. 2021
        分担
      • (2019年度分)
        難治性疾患等政策研究事業
        From 01 Apr. 2019, To 31 Mar. 2020
        分担
      • (平成29年度分)
        難治性疾患等政策研究事業(難治性疾患政策研究事業)
        From 01 Apr. 2017, To 31 Mar. 2018
        分担
      • (平成30年度分)
        難治性疾患等政策研究事業(難治性疾患政策研究事業)
        From 01 Apr. 2018, To 31 Mar. 2019
        分担
      list
        Last Updated :2023/01/25

        Education

        Teaching subject(s)

        • From Apr. 2015, To Mar. 2016
          Clinical Overview of Internal Medicine III
          Spring, 医学部(人間健康科学科)
        • From Apr. 2016, To Mar. 2017
          Clinical Overview of Internal Medicine III
          Spring, 医学部(人間健康科学科)
        • From Apr. 2017, To Mar. 2018
          Clinical Overview of Internal Medicine III
          Spring, 医学部(人間健康科学科)

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