Basic Information

Academic Degree

• (Kyoto University)

Research History

• From Apr. 2015, To Mar. 2017

  日本赤十字社 福井赤十字病院, 放射線科

ID,URL

• J-Global ID

  202101006275463487

Research

Research Topics, Overview of the research

• Research Topics

  high-precision radiation therapy

• Overview of the research

  Clinical research on high-precision radiotherapy, mainly for urological tumors.

Research Interests

• 前立腺癌
• 放射線治療

Research Areas

• Life sciences, Radiology

Papers

• [Evaluation of the Intra-fractional Motion in Stereotactic Body Radiation Therapy for Metastatic Spinal Tumors].

  Teruyo Sugiura; Norimasa Matsushita; Makoto Sasaki; Takahiro Fujimoto; Manabu Nakata; Hideaki Hirashima; Rihito Aizawa; Takashi Mizowaki

  Nihon Hoshasen Gijutsu Gakkai zasshi, 2026

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• Stereotactic Body Radiation Therapy for Spinal Metastasis Using Biaxially Rotational Dynamic Radiation Therapy (BROAD-RT).

  Akira Ueta; Rihito Aizawa; Yuka Ono; Yusuke Iizuka; Kiyonao Nakamura; Nobutaka Mukumoto; Hideaki Hirashima; Mitsuhiro Nakamura; Takashi Mizowaki

  Anticancer research, Jan. 2026

  
• Computed Tomography-Based Radiomics Prediction of Biochemical Failure and Distant Metastasis in Patients With High- and Very High-Risk Localized Prostate Cancer.

  Takanori Adachi; Kota Hirata; Rihito Aizawa; Hideaki Hirashima; Takashi Ogata; Mitsuhiro Nakamura; Takashi Mizowaki

  Advances in radiation oncology, Dec. 2025

  
• Online adaptive radiation therapy for muscle-invasive bladder cancer: short-course and high-precision definitive treatment for elderly or medically fragile patients.

  Peter J K Tokuda; Rihito Aizawa; Hiraku Iramina; Takahsi Ogata; Hideaki Hirashima; Yuki Kita; Takayuki Sumiyoshi; Takashi Kobayashi; Takashi Mizowaki

  Japanese journal of radiology, 10 Oct. 2025

  
• Protocol summary of a randomized controlled phase III trial for confirming the superiority of local radiotherapy for prostate cancer patients with high-volume metastasis sensitive to hormonal therapy: the JCOG2011 (HimeRT study).

  Naoki Terada; Keiji Nihei; Rihito Aizawa; Shintaro Narita; Takahiro Kojima; Masaki Shiota; Shusuke Akamatsu; Takahiro Kimura; Takahiro Inoue; Mikio Sugimoto; Yuta Sekino; Keita Sasaki; Taro Shibata; Haruhiko Fukuda; Hiroyuki Nishiyama; Hiroshi Kitamura; Takashi Mizowaki

  Japanese journal of clinical oncology, 06 Oct. 2025

  
• BROAD-RTで根治的治療を施行された非転移性前立腺癌の多施設前向き観察研究の治療成績

  緒方 隆司; 相澤 理人; 中村 清直; 坂本 隆吏; 高山 賢二; 松尾 幸憲; 溝脇 尚志

  日本癌治療学会学術集会抄録集, Oct. 2025

  
• Development of a novel risk model to predict CRPC progression following IMRT: Implications for tailoring treatment intensity

  Takashi Ogata; Rihito Aizawa; Hiroyasu Abe; Takayuki Goto; Kiyonao Nakamura; Yuki Kita; Takayuki Sumiyoshi; Kaoru Murakami; Kei Mizuno; Satoshi Morita; Takashi Kobayashi; Takashi Mizowaki

  BJUI Compass, 07 Sep. 2025

  
• 脊椎転移に対して可変軌道を用いた体幹部定位放射線治療の長期治療成績および有害事象

  上田 哲; 相澤 理人; 小野 幸果; 飯塚 裕介; 中村 清直; 椋本 宜学; 平島 英明; 中村 光宏; 溝脇 尚志

  日本癌治療学会学術集会抄録集, Oct. 2024

  
• Clinical Outcomes of Metastasis-directed Therapy for Oligo-metastatic Prostate Cancer Diagnosed Using PSMA-PET/CT or Whole-body MRI.

  Rihito Aizawa; Takashi Ogata; Takayuki Goto; Tomoaki Otani; Kiyonao Nakamura; Yuki Kita; Ryusuke Nakamoto; Yoichi Shimizu; Takayuki Sumiyoshi; Kaoru Murakami; Kei Mizuno; Takashi Kobayashi; Yuji Nakamoto; Takashi Mizowaki

  Anticancer research, Jun. 2025

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• Highly hypofractionated biaxially rotational dynamic radiation therapy (BROAD-RT) for high-risk prostate cancer.

  Rihito Aizawa; Takashi Ogata; Takayuki Goto; Kiyonao Nakamura; Kenji Takayama; Ryo Ashida; Yuki Kita; Takayuki Sumiyoshi; Kaoru Murakami; Kei Mizuno; Takashi Kobayashi; Takashi Mizowaki

  Cancer science, Apr. 2025

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• The real prevalence and clinical courses of non-metastatic castration-resistant prostate cancer: a retrospective single-institutional study.

  Hajime Takamori; Takayuki Goto; Soki Kashima; Takayuki Yoshino; Takashi Ogata; Rihito Aizawa; Kiyonao Nakamura; Takeshi Sano; Atsuro Sawada; Shusuke Akamatsu; Toshinari Yamasaki; Takahiro Inoue; Takashi Mizowaki; Osamu Ogawa; Takashi Kobayashi

  Japanese journal of clinical oncology, 17 Jan. 2025

  
• Impact of diaphragm motion on dosimetry in lower thoracic spine stereotactic body radiotherapy

  Kohei Kawata; Hideaki Hirashima; Manabu Nakata; Takahiro Fujimoto; Rihito Aizawa; Takashi Mizowaki

  Physica Medica, Jan. 2025

  
• Significance of androgen‐deprivation therapy for intermediate‐ and high‐risk prostate cancer treated with high‐dose radiotherapy: A literature review

  Rihito Aizawa; Hitoshi Ishikawa; Manabu Kato; Shosei Shimizu; Takashi Mizowaki; Yasuo Kohjimoto; Shiro Hinotsu; Isao Hara

  International Journal of Urology, 17 Jul. 2024, Lead author

  
• Evaluation of internal margins for prostate for step and shoot intensity‐modulated radiation therapy and volumetric modulated arc therapy using different margin formulas

  Daiki Higuchi; Tomohiro Ono; Ryo Kakino; Rihito Aizawa; Naoki Nakayasu; Hitoshi Ito; Takashi Sakamoto

  Journal of Applied Clinical Medical Physics, 19 Jun. 2022

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• Intensity-modulated radiation therapy for prostate cancer after rectal surgery: a single hospital long-term safety analysis

  Shuang Zhang; Kiyonao Nakamura; Rihito Aizawa; Shusuke Akamatsu; Takashi Mizowaki

  International Journal of Clinical Oncology, 05 Feb. 2022

  
• Clinical factors predicting the outcome of salvage radiotherapy for patients with biochemical recurrence after radical prostatectomy.

  Takeru Fujimoto; Takayuki Goto; Rihito Aizawa; Takashi Ogata; Kiyonao Nakamura; Takayuki Sumiyoshi; Yuki Kita; Kimihiko Masui; Takeshi Sano; Atsuro Sawada; Ryoichi Saito; Shusuke Akamatsu; Takashi Mizowaki; Takashi Kobayashi

  International journal of clinical oncology, Sep. 2024

  
• Spatial Pattern of Intraprostatic Recurrence after Definitive External-Beam Radiation Therapy for Prostate Cancer: Implications for Focal Boost to Intraprostatic Dominant Lesion.

  Rihito Aizawa; Tomoaki Otani; Takashi Ogata; Yusaku Moribata; Aki Kido; Shusuke Akamatsu; Takayuki Goto; Kimihiko Masui; Takayuki Sumiyoshi; Yuki Kita; Takashi Kobayashi; Yuji Nakamoto; Takashi Mizowaki

  Advances in radiation oncology, Jun. 2024, Lead author

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• Long-term safety of high-dose whole pelvic IMRT for high-risk localized prostate cancer through 10-year follow-up

  Rihito Aizawa; Kiyonao Nakamura; Yoshiki Norihisa; Takashi Ogata; Takahiro Inoue; Toshinari Yamasaki; Takashi Kobayashi; Shusuke Akamatsu; Osamu Ogawa; Takashi Mizowaki

  International Journal of Clinical Oncology, 01 Nov. 2021, Lead author

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• Long-term outcomes of an esophagus-preserving chemoradiotherapy strategy for patients with endoscopically unresectable stage I thoracic esophageal squamous cell carcinoma

  Tatsuya Suwa; Yuichi Ishida; Yoshiharu Negoro; Fusako Kusumi; Yoshio Kadokawa; Rihito Aizawa; Toshifumi Nakajima; Yoshiaki Okamoto; Yoshishige Okuno; Kazunari Yamada; Masakazu Ogura; Masao Murakami; Takashi Mizowaki

  Clinical and Translational Radiation Oncology, 01 Sep. 2021

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• 前立腺摘除術後の生化学的再発に対する救済放射線治療の予後予測因子に関する研究

  藤本 健尊; 後藤 崇之; 相澤 理人; 緒方 隆司; 中村 清直; 松岡 崇志; 河野 仁; 住吉 崇幸; 北 悠希; 増井 仁彦; 佐野 剛視; 澤田 篤郎; 溝脇 尚志; 小林 恭; 赤松 秀輔

  日本癌治療学会学術集会抄録集, Oct. 2022

  
• Impact of prostate position-based image-guidance in intensity-modulated radiation therapy for localized prostate cancer

  Rihito Aizawa; Haruo Inokuchi; Itaru Ikeda; Kiyonao Nakamura; Takashi Ogata; Shusuke Akamatsu; Takayuki Goto; Kimihiko Masui; Takayuki Sumiyoshi; Yuki Kita; Takashi Kobayashi; Takashi Mizowaki

  International Journal of Clinical Oncology, 08 Jan. 2024, Lead author

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• Current trends in the promising immune checkpoint inhibition and radiotherapy combination for locally advanced and metastatic urothelial carcinoma

  Takeshi Sano; Ryoichi Saito; Rihito Aizawa; Tsubasa Watanabe; Kaoru Murakami; Yuki Kita; Kimihiko Masui; Takayuki Goto; Takashi Mizowaki; Takashi Kobayashi

  International Journal of Clinical Oncology, 24 Oct. 2023

  
• Impact of Long-term Adjuvant Hormonal Therapy in High-dose IMRT for Unfavorable Locally Advanced Prostate Cancer.

  Takashi Ogata; Rihito Aizawa; Kiyonao Nakamura; Takashi Kobayashi; Shusuke Akamatsu; Eijiro Nakamura; Osamu Ogawa; Takashi Mizowaki

  Anticancer research, Aug. 2023

  
• Efficacy and Tolerability of Second-line Pembrolizumab With Radiation Therapy in Advanced Urothelial Carcinoma.

  Takeshi Sano; Rihito Aizawa; Katsuhiro Ito; Kiyonao Nakamura; Takashi Ogata; Masashi Takeda; Akihiro Hamada; Takashi Matsuoka; Jin Kono; Yuki Kita; Kimihiko Masui; Takayuki Goto; Atsuro Sawada; Shusuke Akamatsu; Osamu Ogawa; Takashi Mizowaki; Takashi Kobayashi

  Anticancer research, May 2023

  
• Efficacy and Safety of External-beam Radiation Therapy for Unresectable Primary or Local Recurrent Cholangiocarcinoma

  TAKASHI MURAKAMI; RIHITO AIZAWA; YUKINORI MATSUO; HIDEKI HANAZAWA; KOJIRO TAURA; AKIHISA FUKUDA; NORIMITSU UZA; MASAHIRO SHIOKAWA; MASASHI KANAI; ETSURO HATANO; HIROSHI SENO; MANABU MUTO; TAKASHI MIZOWAKI

  Cancer Diagnosis & Prognosis, 03 Nov. 2022, Corresponding author

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• Ten-year outcomes of whole-pelvic intensity-modulated radiation therapy for prostate cancer with regional lymph node metastasis.

  Kiyonao Nakamura; Yoshiki Norihisa; Itaru Ikeda; Haruo Inokuchi; Rihito Aizawa; Toshiyuki Kamoto; Tomomi Kamba; Takahiro Inoue; Toshinari Yamasaki; Shusuke Akamatsu; Takashi Kobayashi; Osamu Ogawa; Takashi Mizowaki

  Cancer medicine, 19 Dec. 2022

  
• 【泌尿器がんの新しい放射線治療戦略】前立腺がん cN1およびM1症例に対する放射線外部照射療法の新展開

  相澤 理人; 溝脇 尚志

  泌尿器科, Apr. 2020, Lead author

  
• Clinical significance of IDC-P as predictive factor after intensity-modulated radiation therapy

  Rihito Aizawa; Toyonori Tsuzuki; Hironori Haga; Kiyonao Nakamura; Takashi Ogata; Takahiro Inoue; Takashi Kobayashi; Shusuke Akamatsu; Takayuki Goto; Osamu Ogawa; Takashi Mizowaki

  Cancer Science, Jul. 2022, Lead author

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• Narrative review of local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer.

  Naoki Terada; Rihito Aizawa; Keiji Nihei; Masaki Shiota; Takahiro Kojima; Takahiro Kimura; Takahiro Inoue; Hiroshi Kitamura; Mikio Sugimoto; Hiroyuki Nishiyama; Takashi Mizowaki; Toshiyuki Kamoto

  Japanese journal of clinical oncology, 31 May 2022

  
• Detection efficacy of PET/CT with 18F-FSU-880 in patients with suspected recurrent prostate cancer: a prospective single-center study.

  Tomoaki Otani; Tsuneo Saga; Takayoshi Ishimori; Eitaro Kidera; Yoichi Shimizu; Rihito Aizawa; Kiyonao Nakamura; Takayuki Goto; Shusuke Akamatsu; Takashi Mizowaki; Yuji Nakamoto

  Annals of nuclear medicine, Mar. 2022

  
• 局所進行前立腺がんの至適治療戦略 ホルモン療法併用全骨盤IMRT リンパ節領域照射の意義

  溝脇 尚志; 相澤 理人; 中村 清直; 井上 貴博; 小林 恭; 山崎 俊成; 赤松 秀輔; 小川 修

  泌尿器外科, Aug. 2020

  
• Highly hypofractionated intensity-modulated radiation therapy for nonmetastatic prostate cancer with a simultaneous integrated boost to intraprostatic lesions: a planning study.

  Ryo Ashida; Kiyonao Nakamura; Rihito Aizawa; Hiraku Iramina; Kenji Takayama; Mitsuhiro Nakamura; Takashi Mizowaki

  Japanese journal of radiology, 05 Aug. 2021

  
• Long-term clinical outcomes of external beam radiation therapy for oligometastatic prostate cancer: A combination of prostate-targeted treatment and metastasis-directed therapy.

  Rihito Aizawa; Kenji Takayama; Kiyonao Nakamura; Takashi Ogata; Takahiro Inoue; Toshinari Yamasaki; Takashi Kobayashi; Shusuke Akamatsu; Yu Tashiro; Hideto Ota; Osamu Ogawa; Takashi Mizowaki

  International journal of urology : official journal of the Japanese Urological Association, 02 Apr. 2021, Lead author

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• Increased risk of disease progression in younger men: Analysis of factors predicting biochemical failure and castration-resistant prostate cancer after high-dose intensity-modulated radiation therapy for nonmetastatic prostate cancer.

  Rihito Aizawa; Kenji Takayama; Kiyonao Nakamura; Takahiro Inoue; Toshinari Yamasaki; Takashi Kobayashi; Shusuke Akamatsu; Osamu Ogawa; Takashi Mizowaki

  Urologic oncology, Feb. 2021, Lead author

  
• Long-term clinical outcomes of salvage pelvic radiation therapy for oligo-recurrent pelvic lymph nodes after definitive external-beam radiation therapy for non-metastatic prostate cancer.

  Genki Edward Sato; Rihito Aizawa; Kiyonao Nakamura; Kenji Takayama; Takahiro Inoue; Toshinari Yamasaki; Takashi Kobayashi; Shusuke Akamatsu; Osamu Ogawa; Takashi Mizowaki

  Journal of radiation research, 06 Jul. 2020

  
• Low incidence of late recurrence in patients with intermediate-risk prostate cancer treated by intensity-modulated radiation therapy plus short-term androgen deprivation therapy.

  Rihito Aizawa; Kenji Takayama; Kiyonao Nakamura; Takahiro Inoue; Toshinari Yamasaki; Takashi Kobayashi; Shusuke Akamatsu; Osamu Ogawa; Takashi Mizowaki

  International journal of clinical oncology, Apr. 2020, Lead author

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• Ten-year outcomes of high-dose intensity-modulated radiation therapy for nonmetastatic prostate cancer with unfavorable risk: early initiation of salvage therapy may replace long-term adjuvant androgen deprivation.

  Rihito Aizawa; Kenji Takayama; Kiyonao Nakamura; Takahiro Inoue; Toshinari Yamasaki; Takashi Kobayashi; Shusuke Akamatsu; Osamu Ogawa; Takashi Mizowaki

  International journal of clinical oncology, Oct. 2019, Lead author

  
• Radiation-induced cystic brain necrosis developing 10 years after linac-based stereotactic radiosurgery for brain metastasis.

  Rihito Aizawa; Megumi Uto; Keiichi Takehana; Yoshiki Arakawa; Susumu Miyamoto; Takashi Mizowaki

  Oxford medical case reports, Nov. 2018, Lead author

  
• Long-term outcomes of definitive external-beam radiotherapy for non-metastatic castration-resistant prostate cancer.

  Rihito Aizawa; Kenji Takayama; Kiyonao Nakamura; Takahiro Inoue; Takashi Kobayashi; Shusuke Akamatsu; Toshinari Yamasaki; Osamu Ogawa; Takashi Mizowaki

  International journal of clinical oncology, Aug. 2018, Lead author

  
• The Use of External-beam Radiotherapy for Muscle-invasive Bladder Cancer in Elderly or Medically-fragile Patients.

  Rihito Aizawa; Masato Sakamoto; Nobuaki Orito; Masanori Kono; Masakazu Ogura; Yoshiharu Negoro; Tadashi Sagoh; Kenji Tsukahara; Kazuto Komatsu; Masato Noguchi

  Anticancer research, Oct. 2017, Lead author, Corresponding author

  
• Severe esophagitis associated with cytomegalovirus during concurrent chemoradiotherapy for esophageal cancer.

  Rihito Aizawa; Shigemi Matsumoto; Yu Uneno; Yoshitaka Nishikawa; Yoshinao Ozaki; Yukiko Mori; Masashi Kanai; Yuichi Ishida; Katsuyuki Sakanaka; Masahiro Hiraoka; Manabu Muto

  Japanese journal of clinical oncology, 01 Sep. 2017, Lead author

  

Misc.

• 【高リスク前立腺癌の治療戦略】強度変調放射線治療

  相澤 理人; 溝脇 尚志

  Prostate Journal, Oct. 2019

  

Awards

• 21 Oct. 2020

  Japan Society of Clinical Oncology, 第20回日本癌治療学会研究奨励賞
• 20 Oct. 2018

  Japan Society of Clinical Oncology, 第56回日本癌治療学会学術集会優秀演題賞
• 24 Oct. 2019

  Japan Society of Clinical Oncology, 第57回日本癌治療学会学術集会優秀演題賞

External funds: Kakenhi

• Development of an innovative radiation therapy approach to non-metastatic ultra-high risk prostate cancer

  Grant-in-Aid for Scientific Research (B)

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  溝脇 尚志

  From 01 Apr. 2022, To 31 Mar. 2027, Granted

  前立腺癌;放射線療法;寡分割照射;強度変調同時ブースト照射;超高リスクがん;骨盤照射

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H03022/
• 前立腺癌放射線治療後局所再発に対する革新的な救済局所再照射アプローチの開発

  Grant-in-Aid for Early-Career Scientists

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  相澤 理人

  From 01 Apr. 2023, To 31 Mar. 2028, Granted

  前立腺癌;外部放射線治療;局所再発;再照射;体幹部定位放射線治療;Prostate cancer;re-irradiation;locally recurrent

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K14892/
• Development of an innovative radiotherapy approach for non-metastatic very high-risk prostate cancer.

  Grant-in-Aid for Scientific Research (B)

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  溝脇 尚志

  From 01 Apr. 2024, To 31 Mar. 2027, Granted

  前立腺癌;放射線治療;高度寡分割照射;全骨盤照射;超高リスク;寡分割照射;強度変調放射線治療;放射線療法;強度変調同時ブースト照射;超高リスクがん;骨盤照射

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K24283/

External funds: others

• 非転移性前立腺癌への根治的放射線治療後再発を予測するリスクモデルの開発

  藤原記念財団奨励金

  From 01 Jul. 2021, To 31 Mar. 2022

  相澤理人