Basic Information

Faculty

• Faculty of Engineering

Concurrent Affiliation

• Center for the Promotion of Interdisciplinary Education and Research (C-PiER), スーパーグローバルコース 化学系ユニット

Professional Memberships

• 日本化学会
• 高分子学会

Academic Degree

• 修士（工学）(京都大学)
• 博士（工学）(京都大学)

Research History

• Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering, Associate Professor

ID,URL

• J-Global ID

  200901059960840782

• External link

  http://www.tmd.ac.jp/i-mde/www/org/jpn/index.html

researchmap URL

• https://researchmap.jp/read0057369

Research

Research Interests

• 疎水化多糖
• リポソーム
• 有機—無機ハイブリッド
• 人工細胞

Research Areas

• Nanotechnology/Materials, Biochemistry
• Nanotechnology/Materials, Functional solid-state chemistry
• Nanotechnology/Materials, Polymer chemistry
• Life sciences, Bioorganic chemistry
• Nanotechnology/Materials, Structural/physical organic chemistry
• Nanotechnology/Materials, Nano/micro-systems
• Nanotechnology/Materials, Nanobioscience
• Nanotechnology/Materials, Nanomaterials

Misc.

• Molecular chaperone-like activity of hydrogel nanoparticles of hydrophobized pullulan: Thermal stabilization with refolding of carbonic anhydrase B

  K Akiyoshi; Y Sasaki; J Sunamoto

  BIOCONJUGATE CHEMISTRY, May 1999

  
• "Hydrogel Nanoparticles Fromed by Self-Aggregation of Hydrophobized Polysaccharides"

  in proceedings of the American Chemical Society Division of Polymeric Materials ; Science and Engineering American Chemical Society, 1998

  
• A novel hydrophobized polysaccharidel ancoprotein complex Vaccinc induced in vitro and in vivo celluller and humoral immune responses against HER2-expressing murine sarcomas

  Cancer Research., 1998

  
• Controlled association of hydrophobized polysaccharide by cyclodextrin

  Kazunari Akiyoshi; Yoshihiro Sasaki; Kenichi Kuroda; Junzo Sunamoto

  Chemistry Letters, 1998

  
• 疎水化多糖とシクロデキストリンとの会合制御

  1997

  
• "Controlled Association of Macromolecules in Water ; Hydrophobized Polymers and Proteins"

  in Proceedings of Molecular Interactions and Time-Space Organization in Macromolecular systems

  

External funds: Kakenhi

• 膜タンパク質超集積化のための無細胞固相合成システムの開発

  Grant-in-Aid for Challenging Research (Pioneering)

  Medium-sized Section 90:Biomedical engineering and related fields

  Kyoto University

  佐々木 善浩

  From 09 Jul. 2021, To 31 Mar. 2026, Granted

  膜タンパク質;無細胞蛋白質合成;固相合成法;人工細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K18324/
• Investigation of Decellularized Tissue Functions to Obtain Guidelines for Designing Destination Use Devices

  Grant-in-Aid for Scientific Research (A)

  Medium-sized Section 90:Biomedical engineering and related fields

  Institute of Science Tokyo;Tokyo Medical and Dental University

  岸田 晶夫

  From 05 Apr. 2021, To 31 Mar. 2026, Granted

  組織工学;脱細胞化組織;再生医療;細胞外小胞;免疫反応;細胞外マトリックス;マトリックス結合型ベシクル;埋込型医療デバイス;細胞外小胞体

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21H04954/
• Creation of artificial enveloped virus equipped with membrane proteins and exploring of the cellular functions

  Grant-in-Aid for Scientific Research (B)

  Basic Section 37010:Bio-related chemistry

  Tottori University

  Kazunori MATSUURA

  From 01 Apr. 2018, To 31 Mar. 2021, Project Closed

  人工ウイルスキャプシド;エンベロープ;β-アニュラスペプチド;自己集合;膜タンパク質;人工ウイルスキャプシ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18H02089/
• Establishment of novel cell cycle control method using DDS with nanomagnetic composite molecule and application to cancer treatment

  Grant-in-Aid for Scientific Research (B)

  Tokyo Medical and Dental University

  Keiichi Morita

  From 01 Apr. 2016, To 31 Mar. 2019, Project Closed

  口腔がん;分子標的治療薬;細胞周期;ナノゲル;ナノ材料;癌

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16H05510/
• Fabrication of membrane morphogenic materials for nano medicine

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Yoshihiro Sasaki

  From 01 Apr. 2016, To 31 Mar. 2020, Project Closed

  ナノバイオ;ナノ材料;脂質;超薄膜;超分子;超分子化学;ナノチューブ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16H03842/
• Development of a micro drug delivery system using the nanogel-Fe3O4 hybrid and biological implant neodymium magnet

  Grant-in-Aid for Challenging Exploratory Research

  Tokyo Medical and Dental University

  Keiichi MORITA

  From 01 Apr. 2013, To 31 Mar. 2015, Project Closed

  ナノ磁性複合分子;ドラッグデリバリーシステム;口腔がん

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25670853/
• Construction lipid nanotubes for control of cellular functions

  Grant-in-Aid for Young Scientists (A)

  Kyoto University;Tokyo Medical and Dental University

  Yoshihiro SASAKI

  From 01 Apr. 2011, To 31 Mar. 2015, Project Closed

  脂質ナノチューブ;ナノ粒子;細胞間コミュニケーション;人工細胞膜;リポソーム;せん断流

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23681021/
• ソフトナノ粒子を基盤とする有機ー無機ハイブリッドの創成とバイオ応用

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Science and Engineering

  Kyoto University;Tokyo Medical and Dental University

  佐々木 善浩

  From 01 Apr. 2011, To 31 Mar. 2013, Project Closed

  ナノゲル;有機ー無機ハイブリッド;ヒドロキシアパタイト;バイオミネラリゼーション;両親媒性高分子;有機-無機ハイブリッド;ソフトナノ粒子;酸化鉄ナノ微粒子;ナノバイオ

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-23107510/
• Development of cancer-controlling vector conversion techniques using nano-DDS

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  Kazunari AKIYOSHI

  From 01 Apr. 2010, To 31 Mar. 2015, Project Closed

  ドラッグデリバリーシステム;がん治療;ナノゲル;ワクチン;エクソソーム;siRNA;腫瘍微小環境;細胞特異性;RGDペプチド;抗体;サイトカイン;タンパク質デリバリー;核酸デリバリー;エンドサイトーシス;遺伝子導入;シャペロン機能

  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-22114009/
• Comprehensive Research on Fusion Materials: Creative Development of Materials and Exploration of Their Function through Molecular Control

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Science and Engineering

  The University of Tokyo

  Takashi KATO

  From 01 Apr. 2010, To 31 Mar. 2016, Project Closed

  ハイブリッド材料;機能性高分子;融合マテリアル;自己組織化;分子制御;バイオミネラリゼーション;液晶;液晶材料;公開シンポジウム;若手育成;アウトリーチ;ニューズレター;ホームページ研究紹介

  https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-22107001/
• Development ofnew nanogel-based drug delivery systems

  Grant-in-Aid for Scientific Research (A)

  Kyoto University;Tokyo Medical and Dental University

  Kazunari AKIYOSHI

  From 01 Apr. 2008, To 31 Mar. 2013, Project Closed

  ナノゲル;ヒドロゲル;タンパク質;ドラッグデリバリー;細胞機能;多糖;タンパク質デリバリー;核酸デリバリー;反応性ナノゲル;骨形成;ビタミンB6;リポソーム;Schiff塩基;ドラッグデリバリーシステム;再生医療用足場材料;ナノゲル架橋微粒子;プロスタグランジンE1;骨再生;アパタイト;有機-無機ハイブリッド

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20240047/
• 光分子スイッチによる人工細胞ソーティング

  Grant-in-Aid for Young Scientists (B)

  Nara Institute of Science and Technology

  佐々木 善浩

  From 01 Apr. 2005, To 31 Mar. 2007, Project Closed

  ジェミニ型脂質;人工細胞膜;脂質二分子膜ベシクル;多細胞モデル;光応答性;相転移;ベシクルソーティング;アゾベンゼン

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17750159/
• 階層的人工多細胞システムの反応ダイナミクス解析

  Grant-in-Aid for Scientific Research on Priority Areas

  Science and Engineering

  Nara Institute of Science and Technology

  菊池 純一

  From 01 Apr. 2005, To 31 Mar. 2007, Project Closed

  自己組織化;超薄膜;表面・界面物性;ナノ材料;人工多細胞システム;セラソーム

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17034043/
• ジェミニ型脂質による人工細胞膜モルフォロジー制御

  Grant-in-Aid for Young Scientists (B)

  Nara Institute of Science and Technology

  佐々木 善浩

  From 01 Apr. 2003, To 31 Mar. 2005, Project Closed

  ジェミニ型脂質;人工細胞膜;脂質二分子膜ベシクル;多細胞膜モデル;擬クラウンエーテル;イオン認識;相転移

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15750145/
• Preparation and Functionalization of Artificial Multi-cellular Systems by employing Organic-Inorganic Hybrid Nanocapsules

  Grant-in-Aid for Scientific Research (A)

  Nara Institute of Science and Technology

  Jun-ichi KIKUCHI

  From 01 Apr. 2003, To 31 Mar. 2006, Project Closed

  ナノバイオ;人工細胞;有機-無機複合体;自己組織化;分子デバイス;セラソーム;ナノカプセル;人工多細胞;分子間コミュニケーション, Nano-Bio;Artificial Cell;Organic-Inorganic Hybrid;Self organization;Molecular Device;Cerasome

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15205022/
• DEVELOPMENT OF SYNTHETIC LIPOSOMES WITH CERAMIC SURFACE AND THEIR NOVEL FUNCTIONS

  Grant-in-Aid for Scientific Research (B)

  NARA INSTITUTE OF SCIENCE AND TECHNOLOGY

  Jun-ichi KIKUCHI

  From 01 Apr. 2000, To 31 Mar. 2003, Project Closed

  有機-無機複合材料;セラソーム;ナノ微粒子;セラミックス;リポソーム;二分子膜;人工多細胞;人工組織;光触媒;分子デバイス;交互積層;多細胞モデル;光触媒機能;ゾル-ゲル法;脂質リポソーム;膜物性, ORGANIC-INORGANIC HYBRID;CERASOME;NANO-PARTICLE;CERAMICS;LIPOSOME;BILAYER MEMBRANE;ARTIFICIAL MULTICELLULAR SYSTEM;ARTIFICIAL ORGAN

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12450364/
• 生体膜の分子進化に関する共同研究

  Grant-in-Aid for Scientific Research (B)

  Nara Institute of Science and Technology

  有賀 克彦

  From 01 Apr. 1999, To 31 Mar. 2002, Project Closed

  脂質の起源;生体膜;分子進化;単分子膜;二分子膜;酸解離;ポリプレニルリン酸;金属イオン;脂質;生命の起源;酸解離定数

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11694161/
• 多孔性テーラーメードゲル材料を用いた柔軟な舌筋の再生

  Grant-in-Aid for Scientific Research (C)

  Basic Section 57060:Surgical dentistry-related

  Tokyo Medical and Dental University

  原田 浩之

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  舌筋;再生;ナノゲル;舌癌;舌筋再生;多孔性ゲル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K10192/
• 生体内トラフィッキングを制御する分子集積ウイルスレプリカの創製

  Grant-in-Aid for Scientific Research (B)

  Basic Section 37010:Bio-related chemistry

  Tottori University

  松浦 和則

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  ウイルスレプリカ;生体内トラフィッキング;エンベロープ;ヘマグルチニン;血液脳関門

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H02199/
• Functional analyses of sugar codes of exosomes and biomedical applications

  Grant-in-Aid for Scientific Research (A)

  Medium-sized Section 90:Biomedical engineering and related fields

  Kyoto University

  秋吉 一成

  From 01 Apr. 2022, To 31 Mar. 2026, Granted

  エクソソーム;糖鎖解析;レクチンマイクロアレイ;レクチンマクロアレイ;糖鎖;レクチンマイクロアレイ解析

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H00585/
• デザイナーマトリックスによる生命現象の理解と制御

  Grant-in-Aid for Transformative Research Areas (A)

  Transformative Research Areas, Section (III)

  Institute of Science Tokyo;Tokyo Medical and Dental University;Nagoya University

  鳴瀧 彩絵

  From 01 Apr. 2023, To 31 Mar. 2028, Granted

  デザイナーマトリックス;ハイドロゲル;粘弾性;ナノゲル

  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-23H04934/
• 生体内トラフィッキングを制御する分子集積ウイルスレプリカの創製

  Grant-in-Aid for Scientific Research (B)

  Basic Section 37010:Bio-related chemistry

  Tottori University

  松浦 和則

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  ウイルスレプリカ;生体内トラフィッキング;エンベロープ;ヘマグルチニン;血液脳関門;核移行シグナル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K23466/
• オルガネラ機能の再構成による細胞オペレーション技術の創出

  Grant-in-Aid for Challenging Research (Pioneering)

  Medium-sized Section 90:Biomedical engineering and related fields

  Kyoto University

  安藤 満

  From 28 Jun. 2024, To 31 Mar. 2028, Granted

  オルガネラ機能再構成;膜タンパク質;無細胞タンパク質合成;ハイブリッド粒子;エネルギー産生

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K21340/
• ワクチンおよびDDSキャリアとしてのエンベロープ型ウイルスレプリカの創製

  Grant-in-Aid for Scientific Research (B)

  Basic Section 37010:Bio-related chemistry

  Tottori University

  松浦 和則

  From 01 Apr. 2025, To 31 Mar. 2028, Granted

  ウイルスレプリカ;エンベロープ;薬物送達;ワクチン;膜タンパク質

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25K01896/

Education

Teaching subject(s)

• From 01 Apr. 2025, To 31 Mar. 2026

  Introduction to Chemical Science and Technology

  7501, Spring, Faculty of Engineering, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Organic Chemistry III (Frontier Chemistry)

  7123, Fall, Faculty of Engineering, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Biomacromolecular Science

  H611, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2025, To 31 Mar. 2026

  Frontiers in the Field of Chemical Biology and Biological Chemistry

  H409, Fall, Graduate School of Engineering, 1.5
• From 01 Apr. 2025, To 31 Mar. 2026

  Biomacromolecular Science, Adv.

  H653, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2025, To 31 Mar. 2026

  Polymer Synthesis

  H649, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2025, To 31 Mar. 2026

  Frontier Chemistry Laboratory I(Frontier Chemistry)

  7135, Spring, Faculty of Engineering, 7
• From 01 Apr. 2025, To 31 Mar. 2026

  Frontier Chemistry Laboratory II(Frontier Chemistry)

  7136, Fall, Faculty of Engineering, 7
• From 01 Apr. 2024, To 31 Mar. 2025

  Organic Chemistry III (Frontier Chemistry)

  7123, Fall, Faculty of Engineering, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Biomacromolecular Science, Adv.

  H653, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2024, To 31 Mar. 2025

  Polymer Synthesis

  H649, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2024, To 31 Mar. 2025

  Biomacromolecular Science

  H611, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2024, To 31 Mar. 2025

  Frontier Chemistry Laboratory II(Frontier Chemistry)

  7136, Fall, Faculty of Engineering, 7
• From 01 Apr. 2024, To 31 Mar. 2025

  Frontier Chemistry Laboratory I(Frontier Chemistry)

  7135, Spring, Faculty of Engineering, 7
• From 01 Apr. 2023, To 31 Mar. 2024

  Organic Chemistry III (Frontier Chemistry)

  7123, Fall, Faculty of Engineering, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Biomacromolecular Science

  H611, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2023, To 31 Mar. 2024

  Frontiers in the Field of Chemical Biology and Biological Chemistry

  H409, Fall, Graduate School of Engineering, 1.5
• From 01 Apr. 2023, To 31 Mar. 2024

  Polymer Synthesis

  H649, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2023, To 31 Mar. 2024

  Biomacromolecular Science, Adv.

  H653, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2023, To 31 Mar. 2024

  Frontier Chemistry Laboratory II(Frontier Chemistry)

  7136, Fall, Faculty of Engineering, 7
• From 01 Apr. 2023, To 31 Mar. 2024

  Frontier Chemistry Laboratory I(Frontier Chemistry)

  7135, Spring, Faculty of Engineering, 7
• From 01 Apr. 2022, To 31 Mar. 2023

  Frontier Chemistry Laboratory II(Frontier Chemistry)

  7136, Fall, Faculty of Engineering, 7
• From 01 Apr. 2022, To 31 Mar. 2023

  Polymer Synthesis

  H649, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2022, To 31 Mar. 2023

  Biomacromolecular Science, Adv.

  H653, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2022, To 31 Mar. 2023

  Biomacromolecular Science

  H611, Spring, Graduate School of Engineering, 1.5
• From 01 Apr. 2022, To 31 Mar. 2023

  Organic Chemistry III (Frontier Chemistry)

  7123, Fall, Faculty of Engineering, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Frontier Chemistry Laboratory I(Frontier Chemistry)

  7135, Spring, Faculty of Engineering, 7
• From Apr. 2013, To Mar. 2014

  Organic Chemistry III (Frontier Chemistry)

  Fall, 工学部
• From Apr. 2013, To Mar. 2014

  Biomacromolecular Science

  Spring, 工学研究科
• From Apr. 2013, To Mar. 2014

  Polymer Synthesis

  Spring, 工学研究科
• From Apr. 2013, To Mar. 2014

  Polymer Chemistry, Adv. 1

  Spring, 工学研究科
• From Apr. 2014, To Mar. 2015

  Organic Chemistry III (Frontier Chemistry)

  Fall, 工学部
• From Apr. 2014, To Mar. 2015

  Polymer Synthesis

  Spring, 工学研究科
• From Apr. 2015, To Mar. 2016

  Organic Chemistry III (Frontier Chemistry)

  Fall, 工学部
• From Apr. 2015, To Mar. 2016

  Biomacromolecular Science

  Spring, 工学研究科
• From Apr. 2015, To Mar. 2016

  Polymer Chemistry, Adv. 1

  Spring, 工学研究科
• From Apr. 2015, To Mar. 2016

  Polymer Synthesis

  Spring, 工学研究科
• From Apr. 2016, To Mar. 2017

  Organic Chemistry III (Frontier Chemistry)

  Fall, 工学部
• From Apr. 2016, To Mar. 2017

  Biomacromolecular Science

  Spring, 工学研究科
• From Apr. 2016, To Mar. 2017

  Polymer Chemistry, Adv. 1

  Spring, 工学研究科
• From Apr. 2016, To Mar. 2017

  Polymer Synthesis

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Organic Chemistry III (Frontier Chemistry)

  Fall, 工学部
• From Apr. 2017, To Mar. 2018

  Biomacromolecular Science

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Polymer Chemistry, Adv. 1

  Spring, 工学研究科
• From Apr. 2017, To Mar. 2018

  Polymer Synthesis

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Organic Chemistry III (Frontier Chemistry)

  Fall, 工学部
• From Apr. 2018, To Mar. 2019

  Biomacromolecular Science

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Biomacromolecular Science, Adv.

  Spring, 工学研究科
• From Apr. 2018, To Mar. 2019

  Polymer Synthesis

  Spring, 工学研究科
• From Apr. 2019, To Mar. 2020

  Organic Chemistry III (Frontier Chemistry)

  Fall, 工学部
• From Apr. 2019, To Mar. 2020

  Biomacromolecular Science

  Spring, 工学研究科
• From Apr. 2019, To Mar. 2020

  Biomacromolecular Science, Adv.

  Spring, 工学研究科
• From Apr. 2019, To Mar. 2020

  Polymer Synthesis

  Spring, 工学研究科
• From Apr. 2020, To Mar. 2021

  Organic Chemistry III (Frontier Chemistry)

  Fall, 工学部
• From Apr. 2020, To Mar. 2021

  Biomacromolecular Science

  Spring, 工学研究科
• From Apr. 2020, To Mar. 2021

  Biomacromolecular Science, Adv.

  Spring, 工学研究科
• From Apr. 2020, To Mar. 2021

  Polymer Synthesis

  Spring, 工学研究科
• From Apr. 2021, To Mar. 2022

  Frontier Chemistry Laboratory I(Frontier Chemistry)

  Spring, 工学部
• From Apr. 2021, To Mar. 2022

  Organic Chemistry III (Frontier Chemistry)

  Fall, 工学部
• From Apr. 2021, To Mar. 2022

  Biomacromolecular Science

  Spring, 工学研究科
• From Apr. 2021, To Mar. 2022

  Biomacromolecular Science, Adv.

  Spring, 工学研究科
• From Apr. 2021, To Mar. 2022

  Polymer Synthesis

  Spring, 工学研究科

Participation in PhD Defense

• Recapitulating Human Development in Spatially and Temporally Controlled Artificial Microenvironments

  Wang Zhe, Graduate School of Engineering, Sub-chief Examiner

  25 Nov. 2024