Basic Information

Email Address

• Email Address

  umetsu.daiki.2tkyoto-u.ac.jp

Professional Memberships

• 日本細胞生物学会
• 日本発生生物学会
• 日本分子生物学会

Academic Degree

• 29 Mar. 2002

  東京大学修士（理学）
• 23 Mar. 2006

  東京大学博士（理学）

Academic Resume (Undergraduate School/Majors)

• 埼玉大学, 理学部分子生物学科, 卒業

Research History

• From Apr. 2026, To Present

  Kyoto University, Graduate School of Biostudies, Program-Specific Associate Professor
• From Apr. 2026, To Present

  京都大学大学院生命科学研究科, 特任准教授
• From Apr. 2023, To Mar. 2026

  Osaka University, Graduate School of Science Department of Biological Sciences, Lecturer
• From Apr. 2016, To Mar. 2023

  東北大学生命科学研究科, 助教
• From Oct. 2014, To Mar. 2016

  理化学研究所 多細胞システム形成研究センター, 研究員
• From Feb. 2014, To Sep. 2014

  理化学研究所 発生・再生科学総合研究センター, 研究員
• From Mar. 2012, To Jan. 2014

  Technische Universität Dresden, Research scientist
• From Apr. 2007, To Feb. 2012

  Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Postdoctoral fellow
• From Apr. 2006, To Mar. 2007

  東京大学分子細胞生物学研究所, ポスドク

ID,URL

• J-Global ID

  201801017091366183

researchmap URL

• https://researchmap.jp/7000022447

Research

Research Interests

• ショウジョウバエ
• 細胞力学
• 組織形成
• 多細胞

Research Areas

• Life sciences, Molecular biology
• Life sciences, Cell biology
• Life sciences, Developmental biology

Papers

• ショウジョウバエ表皮組織に学ぶ秩序の安定化と再構成

  梅津大輝

  生産と技術, Apr. 2026, Invited, Lead author, Last author, Corresponding author

  
• Dual-purpose dynamics emerge from a heterogeneous cell population in Drosophila metamorphosis

  Daiki Wakita; Satoshi Yamaji; Daiki Umetsu; Takeshi Kano

  PLOS Computational Biology, 28 Aug. 2025, Peer-reviewed, Corresponding author

  
• Cell-cell verification architectures underlying multicellular assemblies-an overview from cellular slime molds and animal

  澤井哲; 梅津大輝

  実験医学, 2025, Invited

  
• Reduction of endocytosis and EGFR signaling is associated with the switch from isolated to clustered apoptosis during epithelial tissue remodeling in Drosophila

  Kevin Yuswan; Xiaofei Sun; Erina Kuranaga; Daiki Umetsu

  PLOS Biology, 14 Oct. 2024, Peer-reviewed, Last author, Corresponding author

  
• Numb Suppresses Notch-Dependent Activation of Enhancer of split during Lateral Inhibition in the Drosophila Embryonic Nervous System

  Elzava Yuslimatin Mujizah; Satoshi Kuwana; Kenjiroo Matsumoto; Takuma Gushiken; Naoki Aoyama; Hiroyuki O. Ishikawa; Takeshi Sasamura; Daiki Umetsu; Mikiko Inaki; Tomoko Yamakawa; Martin Baron; Kenji Matsuno

  Biomolecules, 26 Aug. 2024, Peer-reviewed

  
• Nutrient-driven dedifferentiation of enteroendocrine cells promotes adaptive intestinal growth

  Hiroki Nagai; Luis Augusto Eijy Nagai; Sohei Tasaki; Ryuichiro Nakato; Daiki Umetsu; Erina Kuranaga; Masayuki Miura; Yu-ichiro Nakajima

  Developmental Cell, 25 Sep. 2023, Peer-reviewed

  
• Quantitative Analysis of the Coordinated Movement of Cells in a Freely Moving Cell Population

  Daiki Umetsu; Satoshi Yamaji; Daiki Wakita; Takeshi Kano

  Journal of Robotics and Mechatronics, 20 Aug. 2023, Peer-reviewed, Invited, Lead author, Corresponding author

  
• Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation.

  Hideaki Fujita; Junichi Kaneshiro; Maki Takeda; Kensuke Sasaki; Rikako Yamamoto; Daiki Umetsu; Erina Kuranaga; Shuichiro Higo; Takumi Kondo; Yoshihiro Asano; Yasushi Sakata; Shigeru Miyagawa; Tomonobu M Watanabe

  Life science alliance, Jul. 2023, Peer-reviewed

  
• Cell mechanics and cell-cell recognition controls by Toll-like receptors in tissue morphogenesis and homeostasis.

  Daiki Umetsu

  Fly, Dec. 2022, Peer-reviewed, Invited, Lead author, Corresponding author

  
• Compartmentalizing Epithelia by Differential Adhesion

  梅津大輝

  生物物理(Web), 2022, Peer-reviewed, Invited, Lead author, Last author, Corresponding author

  
• Sample Preparation and Imaging of the Pupal Drosophila Abdominal Epidermis.

  Daiki Umetsu

  Methods in molecular biology (Clifton, N.J.), 2022, Invited, Lead author, Last author, Corresponding author

  
• A Novel Cell Vertex Model Formulation that Distinguishes the Strength of Contraction Forces and Adhesion at Cell Boundaries

  Katsuhiko Sato; Daiki Umetsu

  Frontiers in Physics, 22 Jul. 2021, Peer-reviewed, Invited, Last author

  
• Differential cell adhesion implemented by Drosophila Toll corrects local distortions of the anterior-posterior compartment boundary.

  Norihiro Iijima; Katsuhiko Sato; Erina Kuranaga; Daiki Umetsu

  Nature communications, 10 Dec. 2020, Peer-reviewed, Last author, Corresponding author

  
• Reduction of endocytic activity accelerates cell elimination during tissue remodeling of the Drosophila epidermal epithelium.

  Shinichiro Hoshika; Xiaofei Sun; Erina Kuranaga; Daiki Umetsu

  Development (Cambridge, England), 14 Apr. 2020, Peer-reviewed, Last author, Corresponding author

  
• The role of endocytosis for epidermal tissue remodeling during insect metamorphosis

  梅津大輝; 倉永英里奈

  医学のあゆみ, 2020

  
• Competition for Space Is Controlled by Apoptosis-Induced Change of Local Epithelial Topology.

  Alice Tsuboi; Shizue Ohsawa; Daiki Umetsu; Yukari Sando; Erina Kuranaga; Tatsushi Igaki; Koichi Fujimoto

  Current biology : CB, 09 Jul. 2018, Peer-reviewed

  
• Inference of cell mechanics in heterogeneous epithelial tissue based on multivariate clone shape quantification

  Alice Tsuboi; Daiki Umetsu; Erina Kuranaga; Koichi Fujimoto

  Frontiers in Cell and Developmental Biology, 03 Aug. 2017, Peer-reviewed, Invited, Lead author, Corresponding author

  
• Planar polarized contractile actomyosin networks in dynamic tissue morphogenesis

  Daiki Umetsu; Erina Kuranaga

  CURRENT OPINION IN GENETICS & DEVELOPMENT, Aug. 2017, Peer-reviewed, Invited, Lead author

  
• Segmentation and quantitative analysis of epithelial tissues

  Benoit Aigouy; Daiki Umetsu; Suzanne Eaton

  Methods in Molecular Biology, 2016, Peer-reviewed

  
• A local difference in Hedgehog signal transduction increases mechanical cell bond tension and biases cell intercalations along the Drosophila anteroposterior compartment boundary.

  Katrin Rudolf; Daiki Umetsu; Maryam Aliee; Liyuan Sui; Frank Jülicher; Christian Dahmann

  Development (Cambridge, England), 15 Nov. 2015, Peer-reviewed

  
• Signals and mechanics shaping compartment boundaries in Drosophila

  Daiki Umetsu; Christian Dahmann

  WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY, Jul. 2015, Peer-reviewed, Lead author

  
• An RNA Interference Screen for Genes Required to Shape the Anteroposterior Compartment Boundary in Drosophila Identifies the Eph Receptor

  Daiki Umetsu; Sebastian Dunst; Christian Dahmann

  PLOS ONE, Dec. 2014, Peer-reviewed, Lead author

  
• Local Increases in Mechanical Tension Shape Compartment Boundaries by Biasing Cell Intercalations

  Daiki Umetsu; Benoit Aigouy; Maryam Aliee; Liyuan Sui; Suzanne Eaton; Frank Juelicher; Christian Dahmann

  CURRENT BIOLOGY, Aug. 2014, Peer-reviewed, Lead author

  
• Coordinated sequential action of EGFR and Notch signaling pathways regulates proneural wave progression in the Drosophila optic lobe.

  Tetsuo Yasugi; Atsushi Sugie; Daiki Umetsu; Tetsuya Tabata

  Development (Cambridge, England), Oct. 2010, Peer-reviewed

  
• Recognition of pre- and postsynaptic neurons via nephrin/NEPH1 homologs is a basis for the formation of the Drosophila retinotopic map.

  Atsushi Sugie; Daiki Umetsu; Tetsuo Yasugi; Karl-Friedrich Fischbach; Tetsuya Tabata

  Development (Cambridge, England), Oct. 2010, Peer-reviewed

  
• Compartment boundaries Sorting cells with tension

  Daiki Umetsu; Christian Dahmann

  FLY, Jul. 2010, Peer-reviewed, Lead author

  
• A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor.

  Shun Sawatsubashi; Takuya Murata; Jinseon Lim; Ryoji Fujiki; Saya Ito; Eriko Suzuki; Masahiko Tanabe; Yue Zhao; Shuhei Kimura; Sally Fujiyama; Takashi Ueda; Daiki Umetsu; Takashi Ito; Ken-ichi Takeyama; Shigeaki Kato

  Genes & development, 15 Jan. 2010, Peer-reviewed

  
• Increased cell bond tension governs cell sorting at the Drosophila anteroposterior compartment boundary.

  Katharina P Landsberg; Reza Farhadifar; Jonas Ranft; Daiki Umetsu; Thomas J Widmann; Thomas Bittig; Amani Said; Frank Jülicher; Christian Dahmann

  Current biology : CB, 01 Dec. 2009, Peer-reviewed, Lead author

  
• Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is negatively regulated by JAK/STAT.

  Tetsuo Yasugi; Daiki Umetsu; Satoshi Murakami; Makoto Sato; Tetsuya Tabata

  Development (Cambridge, England), Apr. 2008, Peer-reviewed, Lead author

  
• 神経回路形成におけるシナプス前後細胞間認識に必要な因子の網羅的探索:ショウジョウバエ視覚系神経節の形成をモデルとして

  杉江淳; 梅津大輝; 多羽田哲也

  生化学, 2008

  
• Focal adhesion kinase controls morphogenesis of the Drosophila optic stalk.

  Satoshi Murakami; Daiki Umetsu; Yuko Maeyama; Makoto Sato; Shoko Yoshida; Tetsuya Tabata

  Development (Cambridge, England), Apr. 2007, Peer-reviewed

  
• ショウジョウバエ成虫脳における同心円ゾーンと細胞移動による神経回路の構築

  佐藤純; 田井美也子; 梅津大輝; 北田祐介; 多羽田哲也

  生化学, 2007

  
• 神経幹細胞を形成するProneural waveの進行はJAK/STATにより負に制御されている

  多羽田哲也; 八杉徹雄; 梅津大輝; 村上智史; 吉田章子; 佐藤純

  生化学, 2007

  
• The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system.

  Daiki Umetsu; Satoshi Murakami; Makoto Sato; Tetsuya Tabata

  Development (Cambridge, England), Mar. 2006, Peer-reviewed, Lead author

  
• DWnt4 controls the dorsoventral specificity of the optic nerve axonal projection in Drosophila optic system.

  佐藤純; 梅津大輝; 村上智史; 八杉徹雄; 多羽田哲也

  細胞工学, 2006

  
• DWnt4 regulates the dorsoventral specificity of retinal projections in the Drosophila melanogaster visual system.

  Makoto Sato; Daiki Umetsu; Satoshi Murakami; Tetsuo Yasugi; Tetsuya Tabata

  Nature neuroscience, Jan. 2006, Peer-reviewed

  
• Visual system of Drosophila melanogaster: A model system for understanding mechanisms underlying brain development

  吉田章子; 佐藤純; 梅津大輝; 多羽田哲也

  蛋白質 核酸 酵素, 2006, Peer-reviewed

  
• DPP signaling controls development of the lamina glia required for retinal axon targeting in the visual system of Drosophila.

  Shoko Yoshida; Laurent Soustelle; Angela Giangrande; Daiki Umetsu; Satoshi Murakami; Tetsuo Yasugi; Takeshi Awasaki; Kei Ito; Makoto Sato; Tetsuya Tabata

  Development (Cambridge, England), Oct. 2005, Peer-reviewed

  

Misc.

• 大腸菌ホスファチジルセリン合成酵素のN,C両末端における塩基性領域の機能解析

  西野有紀; 古川裕; 梅津大輝; 落合州子; 松岡聡; 松本幸次; 原弘志

  日本遺伝学会大会プログラム・予稿集, 2013

  
• ショウジョウバエ視覚系において眼柄形成に関与する新規遺伝子corsetの解析

  村上智史; 梅津大輝; 佐藤純; 粟崎健; 伊藤啓; 多羽田哲也

  日本発生生物学会大会発表要旨集, 2005

  
• ショウジョウバエ視覚中枢においてJAK/STATシグナルはラミナ神経細胞の分化を制御する

  八杉徹雄; 梅津大輝; 村上智史; 高橋邦明; 西郷薫; 上田龍; 吉田章子; 佐藤純; 多羽田哲也

  日本分子生物学会年会講演要旨集, 2005

  
• ショウジョウバエoptic stalkの生物学的意義とその形成機構

  村上智史; 梅津大輝; 佐藤純; 多羽田哲也

  日本分子生物学会年会講演要旨集, 2005

  
• DWnt4はショウジョウバエ視覚系において視神経投射の背腹方向の特異性を制御する

  佐藤純; 梅津大輝; 村上智史; 粟崎健; 伊藤啓; 多羽田哲也

  日本分子生物学会年会プログラム・講演要旨集, 2004

  
• 発生Drosophila視覚系におけるCG3624,新しいIgスーパーファミリーメンバーの機能解析(原標題は英語)

  村上智史; 梅津大輝; 佐藤純; 粟崎健; 伊藤啓; 多羽田哲也

  日本分子生物学会年会プログラム・講演要旨集, 2004

  
• Wntシグナルによるショウジョウバエ視神経軸索の背腹方向の投射制御

  佐藤純; 梅津大輝; 村上智史; 粟崎健; 伊藤啓; 多羽田哲也

  日本発生生物学会大会発表要旨集, 2004

  
• ショウジョウバエ視覚中枢の投射標的細胞の分化におけるNotchシグナルの制御機構とその役割

  梅津大輝; 村上智史; 佐藤純; 粟崎健; 伊藤啓; 多羽田哲也

  日本分子生物学会年会プログラム・講演要旨集, 2004

  

Presentations

• ショウジョウバエ組織リモデリング時の新生筋形成に対する不要筋の寄与の解明

  梅津大輝

  第12回 日本筋学会学術集会, 01 Aug. 2026, Invited

  
• Cell assembly dynamics at boundaries in epithelial tissues

  Daiki Umetsu

  EPIC Assembly 2026 Symposium: From Biological Complexity to Evolutionary Principles, 15 Mar. 2026, Invited

  
• Temporal coordination of cell degradation and tissue growth by macrophages during muscle remodeling in Drosophila

  Daiki Umetsu

  2025 NTHU-UOsaka Joint Symposium, 29 Sep. 2025, Invited

  
• Emergence of multitasking from heterogeneity in a motile cell population

  脇田大輝; 加納剛史; 梅津大輝

  IIBMP2025, 04 Sep. 2025, Invited

  
• Heterogeneous ECM dynamics regulate cell survival and abdominal epithelium remodeling in Drosophila

  Kevin Yuswan; Daiki Umetsu; Erina Kuranaga

  Joint Meeting of JSCB 77th JSDB 58th, 17 Jul. 2025

  
• Muscle specific time-delayed cargo degradation in macrophages is associated with muscle remodeling in Drosophila

  Daiki Umetsu

  Joint Meeting of JSCB 77th JSDB 58th, 16 Jul. 2025

  
• Histological analysis of Drosophila macrophages retaining fragmented larval muscle tissue for an extended time

  Saki Hirao; Kenji Matsuno; Daiki Umetsu

  Joint Meeting of JSCB 77th JSDB 58th

  
• 筋断片を長時間保持し続けるマクロファージの解剖学的解析

  平尾 咲; 松野 健治; 梅津 大輝

  第12回 細胞競合コロキウム, 05 Mar. 2025

  
• ショウジョウバエの筋組織リモデリングにおけるマクロファージの筋断片保持の分子遺伝学的解析

  小屋裕章; 髙田志瑠; 松野健治; 梅津大輝

  第12回 細胞競合コロキウム, 05 Mar. 2025

  
• Toll7細胞外ドメインを認識コードとした異所的細胞排除の認識様式

  坂爪 俊介; 北村 大樹; 松野 健治; 梅津 大輝

  第12回 細胞競合コロキウム, 05 Mar. 2025

  
• Heterogeneous ECM dynamics regulate cell survival and abdominal epithelium remodeling in Drosophila

  Kevin Yuswan; Daiki Umetsu; Erina Kuranaga

  第47回 日本分子生物学会年会, 29 Nov. 2024

  
• 筋組織リモデリングにおけるマクロファージの機能的特性解明へむけたscRNA-seq解析

  奥野 瑚利美; 松野 健治; 梅津 大輝

  第47回 日本分子生物学会年会, 29 Nov. 2024

  
• 筋肉のリモデリングにおいて筋断片を長時間保持し続けるマクロファージの細胞組織学的解析

  平尾 咲; 松野 健治; 梅津 大輝

  第47回 日本分子生物学会年会, 28 Nov. 2024

  
• Unraveling the genetic regulatory network controlling L-R asymmetry formation in the anterior gut of Drosophila melanogaster

  Florian Lucas Neugebauer; Takamasa Higashi; Daiki Umetsu; Mikiko Inaki; Akira Nakamura; Kenji Matsuno

  第47回 日本分子生物学会年会, 28 Nov. 2024

  
• Differential adhesion by Toll straightens boundaries in epithelium

  Daiki Umetsu

  SWARM2024, 20 Sep. 2024, Invited

  
• Investigation of a role for caspases in muscle fragmentation and remodeling during metamorphosis

  Shiryu Takata; Erina Kuranaga; Kenji Matsuno; Daiki Umetsu

  Japan Drosophila Research Conference 16, 19 Sep. 2024

  
• Heterogeneous ECM dynamics regulate cell survival and abdominal epithelium remodeling in Drosophila

  Kevin Yuswan; Daiki Umetsu; Erina Kuranaga

  Japan Drosophila Research Conference 16, 18 Sep. 2024

  
• Differential adhesion by Toll sets smooth boundaries in the absence of local increase in Myosin II accumulation

  Norihiro Iijima; Erina Kuranaga; Daiki Umetsu

  Self-Organization in Biology: Freiburg Spemann-Mangold Centennial Symposium, 17 Sep. 2024

  
• Live imaging analysis of heterogeneous cell population during the insect muscle remodeling dynamics

  Daiki Umetsu

  第46回 日本分子生物学会年会 シンポジウム 群知能に共通原理は存在する？, 08 Dec. 2023, Invited

  
• ECM dynamics modulate cell elimination patterns to regulate the abdominal epithelium remodeling in Drosophila

  Kevin Yuswan; Xiaofei Sun; Daiki Umetsu; Erina Kuranaga

  第46回 日本分子生物学会年会, 07 Dec. 2023

  
• Live imaging analysis of caspase activity during skeletal muscle histolysis in Drosophila

  Shiryu Takata; Erina Kuranaga; Kenji Matsuno; Daiki Umetsu

  第56回 発生生物学会年会, 23 Jul. 2023

  
• ECM dynamics modulate endocytosis and EGFR signaling to regulate the abdominal epithelium remodeling in Drosophila

  Kevin Yuswan; Xiaofei Sun; Daiki Umetsu; Erina Kuranaga

  第56回 発生生物学会年会, 23 Jul. 2023

  
• 動き回る筋断片による筋組織リサイクル

  梅津大輝

  第10回定量生物学の会, 15 Dec. 2022, Invited

  
• Muscle cell swarm intelligence: Live imaging analysis of the muscle remodeling dynamics during insect metamorphosis

  梅津大輝

  第45回日本分子生物学会年会 ワークショップ 動き回るヘテロな細胞集団の群知能的動態に迫れ, 30 Nov. 2022, Invited

  
• 昆虫変態時の筋組織リモデリングにおける細胞動態

  梅津大輝

  第55回発生生物学会年会 フリースタイルワークショップ, 31 May 2022, Invited

  
• Self-organization of muscle remodeling during insect metamorphosis

  Daiki Umetsu

  金沢大学 新学術創成研究機構 数理神経科学ユニット-栄養代謝研究ユニット 異分野融合セミナー, 11 Mar. 2022, Invited

  
• Reassembly of muscle fragments during skeletal muscle remodeling in Drosophila

  Daiki Umetsu

  The 44th annual meeting of the molecular biology society Japan, 03 Dec. 2021, Invited

  
• Endocytic activity and EGFR signaling regulate the elimination process of larval epidermal cells during the abdominal epithelium remodeling of Drosophila melanogaster

  Kevin Yuswan; Xiaofei Sun; Daiki Umetsu; Erina Kuranaga

  The 44th annual meeting of the molecular biology society of Japan, 02 Dec. 2021

  
• Differential adhesion by Toll sets straight compartment boundaries in the absence of local increase in Myosin II accumulation

  Daiki Umetsu; Norihiro Iijima; Erina Kuranaga

  Japan Drosophila Research Conference 14, 16 Sep. 2021

  
• Shuffling and reassembly of fragmented muscles

  梅津大輝

  JSMB2021 Annual Meeting, 15 Sep. 2021, Invited

  
• Swarm of fragmented muscle shuffles and reassembles into an ordered configuration

  Daiki Umetsu; Erina Kuranaga

  The 43rd Annual Meeting of the Molecular Biology Society of Japan, 04 Dec. 2020, Invited

  
• ミオシンVIの機械刺激応答メカニズムと発生への寄与

  古川晴比古; 川元悠平; 梅津大輝; 倉永英里奈

  第42回日本分子生物学会, Dec. 2019

  
• Identification of the molecules mediating larval epidermal cells death regulated by endocytosis

  Xiaofei Sun; Shinichiro Hoshika; Daiki Umetsu; Erina Kuranaga

  第42回日本分子生物学会, Dec. 2019

  
• Tissue Replacement during Drosophila Metamorphosis as a Model for Morphomeostatic Control of Cell Birth and Death

  Daiki Umetsu

  4th Morphomeostasis Meeting, Sep. 2019, Invited

  
• Differential expression of Toll-1 maintains sharp compartment boundary in proliferating epithelium

  Daiki Umetsu; Norihiro Iijima; Erina Kuranaga

  26th European Drosophila Research Conference, Sep. 2019

  
• 細胞除去を伴う頂端部収縮のエンドサイトーシスによる制御機能

  星加真一朗; 梅津大輝; 倉永英里奈

  第41回日本分子生物学会, Nov. 2018

  
• 組織コンパートメント境界維持機構におけるToll受容体の関与

  飯島寛大; 梅津大輝; 倉永英里奈

  第41回日本分子生物学会, Nov. 2018

  
• 自然免疫センサーTLRは上皮組織パターン形成過程で細胞間接着分子として機能する

  飯島寛大; 梅津大輝; 倉永英里奈

  第41回日本分子生物学会年会, Nov. 2018, Invited

  
• Homeostatic control of cell dynamics during tissue morphogenesis and remodeling

  Daiki Umetsu

  Biologisches Kolloquium, Technische Universität Dresden, Oct. 2018, Invited

  
• First aid of jagged boundaries in the absence of junction Myosin II

  Daiki Umetsu

  3rd Morphomeostasis Meeting, Jun. 2018, Invited

  
• A Drosophila Toll-like receptor family protein prevents cell mixing through homophileic adhesion during epithelial morphogenesis

  Daiki Umetsu; Norihiro Iijima; Erina Kuranaga

  Joint Annual Meeting of JSDB 51st and JSDCB 70th, Jun. 2018

  
• Mechanisms to maintain mechanical boundaries in the epithelium

  Daiki Umetsu

  NanoLSI Open Seminar, Apr. 2018, Invited

  
• Differential expression of an ancient cell surface recognition molecule guides cell sorting at the anteroposterior compartment boundary in Drosophila

  Daiki Umetsu; Norihiro Iijima; Erina Kuranaga

  EMBO|EMBL Symposium: Tissue Self-Organization: Challenging the Systems, Mar. 2018

  
• PTP61Fによる細胞増殖の力学的制御と細胞競合への関与

  梅津 大輝

  新学術領域 「幹細胞老化と疾患」「細胞競合」総括班主催「若手の会」, Feb. 2018

  
• ハエから学ぶ「力が生き物の形をつくるしくみ」

  梅津大輝

  小型魚類研究会 サテライトシンポジウム 第２回 帰ってきた ムシvs.サカナ, Aug. 2017, Invited

  
• Inference of cell mechanics in heterogeneous epithelial tissue based on multivariate clone shape quantification

  梅津 大輝

  第2回 次世代生命科学の研究会, 13 Jul. 2017

  
• Inference of cell mechanics in heterogeneous epithelial tissue based on multivariate clone shape quantification

  Daiki Umetsu

  2nd Morphomeostasis Meeting, Jun. 2017, Invited

  
• Inference of cell mechanics in heterogeneous epithelial tissue based on multivariate clone shape quantification

  Daiki Umetsu; Alice Tsuboi; Koichi Fujimoto; Erina Kuranaga

  4th Asia Pacific Drosophila Research Conference, May 2017

  
• PTP61Fの制御機構が細胞競合と細胞増殖の力学的制御のつながりを示唆する

  梅津 大輝

  新学術領域 細胞競合・ダイイングコード 合同若手ワークショップ, Jan. 2017

  
• A Link between Mechanical Control of Tissue Growth and Cell Competition

  Daiki Umetsu; Erina Kuranaga

  12th Japanese Drosophila Research Conference, 09 Sep. 2016

  
• アクチン細胞骨格と原癌遺伝子Mycによる組織成長制御メカニズム

  Daiki Umetsu

  第一回 次世代生命科学の研究会, 12 Aug. 2016, Invited

  
• A link between mechanical control of tissue growth and cell competition

  Daiki Umetsu

  1st Morphomeostasis Meeting, 26 Jun. 2016, Invited

  
• Identification of mechanisms that protect cells from cell competition at anteroposterior compartment boundary in developing Drosophila wings

  Umetsu, D.; Kuranaga, E.

  1st International Symposium on Cell Competition, Cell Competition in Development and Cancer, Sep. 2015

  
• Tissue proliferation control by mechanical stresses

  Umetsu, D.; Kuranaga, E.

  The 26th CDB Meeting, Mechanistic Perspectives of Multicellular Organization, Sep. 2015

  
• 機械的ストレス応答による組織増殖の制御機構

  梅津大輝; 倉永英里奈

  第27回 高遠・分子細胞生物学シンポジウム, 26 Aug. 2015

  
• Local increases in mechanical tension guide cell sorting along compartment boundaries by biasing cell intercalations

  Daiki Umetsu

  48th Annual Meeting of the Japanese Society of Developmental Biologists, 02 Jun. 2015

  
• PTP61Fの制御機構が細胞競合と細胞増殖の力学的制御のつながりを示唆する

  梅津大輝; 倉永英里奈

  第五回 細胞競合コロキウム, 17 Mar. 2015

  
• コンパートメント境界における細胞競合の防護メカニズムの解明

  梅津大輝; 倉永英里奈

  第四回 細胞競合コロキウム, 12 Mar. 2015

  
• コンパートメント境界における細胞競合の防護機構メカニズムの同定をめざして

  梅津大輝; 倉永英里奈

  第２回新学術領域研究会議 細胞競合, 13 Jan. 2015

  
• 一細胞レベルでの細胞動態の解析から増殖する上皮組織で細胞の混ざり合いを防ぐメカニズムを明らかにする

  Daiki Umetsu; Benoit Aigouy; Maryam Aliee; Suzanne Eaton; Frank Jülicher; Christian Dahmann; Aigouy, B; Aliee, M; Eaton, S; Jülicher, F; Dahmann, C

  定量生物学の会, 11 Jan. 2015

  
• 細胞間接着にかかる張力が細胞介入にバイアスをかけることによってコンパートメント境界を形成する

  Daiki Umetsu; Benoit Aigouy; Maryam Aliee; Suzanne Eaton; Frank Jülicher; Christian Dahmann

  第26回 高遠・分子細胞生物学シンポジウム, 28 Aug. 2014

  
• Local increases in mechanical tension shape compartment boundaries by biasing cell intercalations

  Daiki Umetsu; Benoit Aigouy; Maryam Aliee; Suzanne Eaton; Frank Jülicher; Christian Dahmann

  The Joint Annual Meeting of the Japanese Society for Mathematical Biology and the Society for Mathematical Biology, 28 Jul. 2014, Invited

  
• Local increases in mechanical tension shape compartment boundaries by biasing cell intercalations

  Daiki Umetsu; Benoit Aigouy; Maryam Aliee; Suzanne Eaton; Frank Jülicher; Christian Dahmann

  11th Japanese Drosophila Research Conference, Jun. 2014

  
• Local increases in mechanical tension shape compartment boundaries by biasing cell intercalations

  Daiki Umetsu; Benoit Aigouy; Maryam Aliee; Suzanne Eaton; Frank Jülicher; Christian Dahmann

  47th Annual Meeting of the Japanese Society of Developmental Biologists, May 2014

  
• Local increases in mechanical tension guide cell sorting at compartment boundaries by constraining junctional dynamics

  Daiki Umetsu

  CDB seminar, Aug. 2013

  
• Local increases in mechanical tension guide cell sorting at compartment boundaries by constraining junctional dynamics

  Daiki Umetsu

  セミナー 大阪大学理学研究科, Aug. 2013

  
• Local increases in mechanical tension guide cell sorting at compartment boundaries by constraining junctional dynamics

  Daiki Umetsu; Benoit Aigouy; Suzanne Eaton; Christian Dahmann

  2nd Asia-Pacific Drosophila Research Conference, May 2013

  
• Live imaging reveals dynamics of cell sorting at lineage restriction boundaries in Drosophila

  Daiki Umetsu

  Tissue Growth and Morphogenesis: from Genetics to Mechanics and Back, Jul. 2012, Invited

  
• Increased mechanical tension guides cell sorting at anteroposterior compartment boundaries in Drosophila

  Daiki Umetsu; Katharina Landsberg; Reza Farhadifar; Jonas Ranft; Thomas Widmann; Thomas Bittig; Amani Said; Benoit Aigouy; Suzanne Eaton; Frank Jülicher; Christian Dahmann

  22nd European Drosophila Research Conference, Sep. 2011

  
• Mechanical Tension Guides Cell Sorting at Compartment Boundaries

  Daiki Umetsu; Katharina Landsberg; Reza Farhadifar; Jonas Ranft; Thomas Widmann; Thomas Bittig; Amani Said; Benoit Aigouy; Suzanne Eaton; Frank Jülicher; Christian Dahmann

  1st Asia-Pacific Drosophila Research Conference, May 2011

  
• Mechanical Tension Guides Cell Sorting at the Anteroposterior Compartment Boundary in Drosophila

  Daiki Umetsu; Katharina Landsberg; Reza Farhadifar; Jonas Ranft; Thomas Widmann; Thomas Bittig; Amani Said; Benoit Aigouy; Suzanne Eaton; Frank Jülicher; Christian Dahmann

  44th Annual Meeting for the Japanese Society of Developmental Biologists, May 2011

  
• Mechanical Tension Guides Cell Sorting at the Anteroposterior compartment boundary

  Daiki Umetsu; Katharina Landsberg; Reza Farhadifar; Jonas Ranft; Thomas Widmann; Thomas Bittig; Amani Said; Benoit Aigouy; Suzanne Eaton; Frank Jülicher; Christian Dahmann

  Joint Meeting of the German and Japanese Societies of Developmental Biologists, Mar. 2011

  
• Increased cell bond tension governs cell sorting at the Drosophila anteroposterior compartment boundary

  Daiki Umetsu; Katharina Landsberg; Reza Farhadifar; Jonas Ranft; Thomas Widmann; Thomas Bittig; Amani Said; Benoit Aigouy; Suzanne Eaton; Frank Jülicher; Christian Dahmann

  51st Annual Drosophila Research Conference, Apr. 2010

  
• An RNAi-based screen to identify molecules required for the formation of the anterior-posterior compartment boundary in the Drosophila wing

  Umetsu, D.; Dunst, S.; Dahmann, C.

  21th European Drosophila Research Conference, Nov. 2009

  
• An RNAi based screen to identify molecules required for the formation of the anterior-posterior compartment boundary in Drosophila wings

  Daiki Umetsu

  EMBO fellows meeting, Jun. 2009, Invited

  
• Molecular mechanisms that underlie the transition of neuroepithelial cells to neuroblasts in the Drosophila optic lobe

  Umetsu, D; Yasugi, T.; Sato, M.; Tabata T.

  48th Annual Drosophila Research Conference, Mar. 2007

  
• The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system

  Daiki Umetsu

  IBDM Seminar, Jul. 2006

  
• The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system

  Daiki Umetsu

  CBG seminar, Jul. 2006

  
• The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system

  Umetsu, D.; Murakami, S.; Sato, M.; Tabata, T.

  CDB symposium 2006, Apr. 2006

  
• The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system

  Umetsu, D.; Murakami, S.; Sato, M.; Tabata, T.

  47th Annual Drosophila Research Conference, Mar. 2006

  
• The enhancer trap screens for genes involved in formation of the fly visual center

  Umetsu D.; Murakami S.; Awasaki T.; Ito K.; Tabata, T.

  44th Annual Drosophila Research Conference, Mar. 2003

  

Books and Other Publications

• Sample Preparation and Imaging of the Pupal Drosophila Abdominal Epidermis

  Daiki Umetsu, Contributor

  Humana, New York, NY, 19 Aug. 2022

  
• Segmentation and Quantitative Analysis of Epithelial Tissues.

  Benoit Aigouy; Daiki Umetsu; Suzanne Eaton, Joint work

  12 Oct. 2016, Not refereed

  

Media Coverage

• 阪大と東北大、昆虫の変態で組織の作り替えを加速する仕組みを解明

  日本経済新聞, 17 Oct. 2024, Internet

  
• Protein Tells Developing Cells to Stick Together

  Tohoku University, https://www.tohoku.ac.jp/en/press/protein_tells_developing_cells_to_stick_together.html, 24 Dec. 2020, Internet

  
• 上皮組織の境目を保つのは細胞の接着性の違い 免疫系で働く遺伝子の接着分子としての新機能を発見

  東北大学, https://www.tohoku.ac.jp/japanese/2020/12/press20201211-01-toll.html, 11 Dec. 2020, Internet

  
• 東北大、免疫系で働く遺伝子の接着分子としての新機能を発見

  日本経済新聞, 10 Dec. 2020, Internet

  
• 変態スピードを速めるメカニズムを世界で初めて解明 〜物質の取り込み能力の低下が細胞死の引き金を引く〜

  東北大学, https://www.tohoku.ac.jp/japanese/2020/04/press20200414-02-speed.html, 15 Apr. 2020, Internet

  
• 東北大、昆虫の変態スピードを速めるメカニズムを解明

  日本経済新聞, 14 Apr. 2020, Internet

  
• Protein tells developing cells to stick together

  EurekAlert, https://www.eurekalert.org/pub_releases/2020-12/tu-ptd122420.php, Internet

  

Academic, Social Contribution

Committee Memberships

• From Apr. 2025, To Present

  教務委員, 大阪大学理学部生物科学科
• From Apr. 2024, To Mar. 2025

  研究環境整備委員, 大阪大学理学部生物科学科
• From Apr. 2023, To Mar. 2024

  教務委員, 大阪大学理学部生物科学科
• From Apr. 2016, To Mar. 2023

  安全管理委員, 東北大学理学部生物学科
• From Apr. 2016, To Mar. 2023

  学生実習委員, 東北大学理学部生物学科
• From Apr. 2020, To Mar. 2021

  オープンキャンパス実行委員, 東北大学理学部生物学科
• From Apr. 2020, To Mar. 2021

  学生実習委員長, 東北大学理学部生物学科
• From Apr. 2019, To Mar. 2020

  自然科学総合実験 課題11 課題責任者, 東北大学

Social Contribution

• 生き物のかたちづくりと力

  Lecturer

  理化学研究所多細胞システム形成センター, 高校生のための発生生物学実習講座, From 25 Dec. 2015, To 26 Dec. 2015