Basic Information

Academic Degree

• 博士（医学）(京都大学)

Language of Instruction

• English

ID,URL

• J-Global ID

  201701005807035730

researchmap URL

• https://researchmap.jp/7000020624

Research

Research Topics, Overview of the research

• Research Topics

  Development of prevention method from chemotherapy-induced peripheral neuropathy
  Development of breast cancer prediction model and construction of medical treatment system for high risk group (including familial and hereditary breast cancer)
  Development of breast cancer diagnostic marker using IgG glycosylation etc
  Research on the mechanism and tolerance of hormonal therapy in breast cancer

• Overview of the research

  We are proceeding a clinical research of compression therapy to prevent peripheral neuropathy, which causes lower QOL in breast cancer chemotherapy.
  In addition, using samples and clinical information (thanks to Kyoto University and related facilities and patients), we are conducting 'Development of breast cancer prediction model and construction of medical treatment system for high risk group (including familial and hereditary breast cancer)', 'Development of breast cancer diagnostic marker using IgG glycosylation etc' and
  'Research on the mechanism and tolerance of hormonal therapy in breast cancer'.

Research Interests

• Prevention of side effects
• Chemotherapy-Induced Peripheral Neuropathy
• Hereditary Breast Cancer
• Cancer Prevention
• Systemic Therapy
• Breast Cancer

Research Areas

• Life sciences, General surgery, pediatric surgery

Papers

• 乳癌免疫療法のリアルワールドでの問題点、そして今後の展望 Triple Negative乳癌に対するPembrolizumab併用術前化学療法のMRI評価 早期治療効果予測の可能性

  片岡 正子; 岡澤 藍夏; 川島 雅央; 川口 展子; 河口 浩介; 本田 茉也; 太田 理恵; 飯間 麻美; 山田 洋介; 竹内 康英; 三宅 可奈江; 山口 絢音; 高田 正泰; 中本 裕士

  日本乳癌学会総会プログラム抄録集, Jul. 2024

  
• 自然言語処理による多モダリティ病歴テキストの自動結合データベース化に関する研究

  山口 絢音; 西山 智弘; 工藤 紀子; 河口 浩介; 川島 雅央; 川口 展子; 森 由希子; 荒牧 英治; 高田 正泰; 戸井 雅和

  日本乳癌学会総会プログラム抄録集, Jul. 2024

  
• 乳癌免疫療法のリアルワールドでの問題点、そして今後の展望 Triple Negative乳癌に対するPembrolizumab併用術前化学療法のMRI評価 早期治療効果予測の可能性

  片岡 正子; 岡澤 藍夏; 川島 雅央; 川口 展子; 河口 浩介; 本田 茉也; 太田 理恵; 飯間 麻美; 山田 洋介; 竹内 康英; 三宅 可奈江; 山口 絢音; 高田 正泰; 中本 裕士

  日本乳癌学会総会プログラム抄録集, Jul. 2024

  
• 自然言語処理による多モダリティ病歴テキストの自動結合データベース化に関する研究

  山口 絢音; 西山 智弘; 工藤 紀子; 河口 浩介; 川島 雅央; 川口 展子; 森 由希子; 荒牧 英治; 高田 正泰; 戸井 雅和

  日本乳癌学会総会プログラム抄録集, Jul. 2024

  
• がん遺伝子パネル検査が有用であったTMB-highのER陽性HER2陰性転移性乳癌の一例

  梅島 章裕; 川口 展子; 高田 正泰; 川島 雅央; 河口 浩介; 鈴木 千晶; 森 由希子; 吉岡 正博; 金井 雅史; 武藤 学; 戸井 雅和

  日本癌治療学会学術集会抄録集, Oct. 2023

  
• Predicting invasive disease-free survival in ER-positive, HER2-negative early breast cancer using the PAM50 risk-of-recurrence score: a retrospective analysis using single-center long-term follow-up data of Japanese patients with breast cancer

  Akane Higami; Masahiro Takada; Nobuko Kawaguchi-Sakita; Masahiro Kawashima; Kosuke Kawaguchi; Ayane Yamaguchi; Yasuhide Takeuchi; Yosuke Yamada; Masakazu Kawaguchi Toi

  13 Feb. 2024

  
• Quantitative analysis of the effect of docetaxel-induced edema on quality of life in patients with breast cancer and related factors: a prospective cohort study.

  Tomoko Izawa; Ami Kobayashi; Masahiro Kawashima; Nobuko Kawaguchi-Sakita; Akiyoshi Nakakura; Yuki Kataoka; Kenichiro Shide; Yukiko Mori; Kazuhiro Yamazaki; Masakazu Toi; Harue Arao

  BMC women's health, 07 Mar. 2024

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• Remarkable remission of symptomatic dermatomyositis after curative breast cancer surgery

  Makoto Fujino; Masahiro Kawashima; Hajime Yoshifuji; Ran Nakashima; Yosuke Yamada; Yoshiaki Matsumoto; Nobuko Kawaguchi-Sakita; Yukiko Mori; Fengling Pu; Ayane Yamaguchi; Kosuke Kawaguchi; Masahiro Takada; Masakazu Toi

  International Cancer Conference Journal, 25 Jan. 2024

  
• デュアルトレーサーを用いた乳房専用PETが術前診断に有用であったDCIS症例の検討

  田口 真凜; 三宅 可奈江; 片岡 正子; 川島 雅央; 梅島 章裕; 川西 佳奈; 山口 絢音; 河口 浩介; 鈴木 千晶; 古武 剛; 川口 展子; 森 由希子; 高田 正泰; 竹内 康英; 山田 洋介; 中本 裕士; 戸井 雅和

  日本乳癌学会総会プログラム抄録集, Jun. 2023

  
• Comparison of cisplatin-based versus standard preoperative chemotherapy in patients with operable triple-negative breast cancer: propensity score matching and inverse probability of treatment weighting analysis.

  Ayane Yamaguchi; Kosuke Kawaguchi; Kana Kawanishi; Yurina Maeshima; Akiyoshi Nakakura; Tatsuki R Kataoka; Sachiko Takahara; Shunsaku Nakagawa; Atsushi Yonezawa; Masahiro Takada; Masahiro Kawashima; Nobuko Kawaguchi-Sakita; Takeshi Kotake; Eiji Suzuki; Hanako Shimizu; Masae Torii; Satoshi Morita; Hiroshi Ishiguro; Masakazu Toi

  Breast cancer research and treatment, 21 Dec. 2023

  
• 局所治療のde-escalationを可能にする画像診断 De-escalationを目指した乳房MRI造影および拡散強調画像による術前薬物療法後の乳房内残存腫瘍評価

  片岡 正子; 太田 理恵; 本田 茉也; 飯間 麻美; 岡澤 藍夏; 山田 洋介; 竹内 康英; 三宅 可奈江; 高田 正泰; 川島 雅央; 河口 浩介; 川口 展子; 戸井 雅和; 中本 裕士

  日本乳癌学会総会プログラム抄録集, Jun. 2023

  
• 局所治療のde-escalationを可能にする画像診断 De-escalationを目指した乳房MRI造影および拡散強調画像による術前薬物療法後の乳房内残存腫瘍評価

  片岡 正子; 太田 理恵; 本田 茉也; 飯間 麻美; 岡澤 藍夏; 山田 洋介; 竹内 康英; 三宅 可奈江; 高田 正泰; 川島 雅央; 河口 浩介; 川口 展子; 戸井 雅和; 中本 裕士

  日本乳癌学会総会プログラム抄録集, Jun. 2023

  
• デュアルトレーサーを用いた乳房専用PETが術前診断に有用であったDCIS症例の検討

  田口 真凜; 三宅 可奈江; 片岡 正子; 川島 雅央; 梅島 章裕; 川西 佳奈; 山口 絢音; 河口 浩介; 鈴木 千晶; 古武 剛; 川口 展子; 森 由希子; 高田 正泰; 竹内 康英; 山田 洋介; 中本 裕士; 戸井 雅和

  日本乳癌学会総会プログラム抄録集, Jun. 2023

  
• 15歳女性に発生した悪性葉状腫瘍に対してTP53遺伝学的検査を施行した1例

  岩野 由季; 川口 展子; 中島 健; 河口 浩介; 高田 正泰; 川島 雅央; 松本 純明; 川西 佳奈; 田口 真凜; 梅島 章裕; 戸井 雅和

  日本乳癌学会総会プログラム抄録集, Jun. 2023

  
• 外来化学療法を受けている乳がん患者における味覚障害の実態と栄養管理の在り方について

  小林 亜海; 井沢 知子; 川島 雅央; 中谷 美幸; 川口 展子; 森 由希子; 幣 憲一郎; 原田 範雄; 稲垣 暢也

  日本病態栄養学会誌, Jan. 2023

  
• Visualization of tumor-related blood vessels in human breast by photoacoustic imaging system with a hemispherical detector array

  M. Toi; Y. Asao; Y. Matsumoto; H. Sekiguchi; A. Yoshikawa; M. Takada; M. Kataoka; T. Endo; N. Kawaguchi-Sakita; M. Kawashima; E. Fakhrejahani; S. Kanao; I. Yamaga; Y. Nakayama; M. Tokiwa; M. Torii; T. Yagi; T. Sakurai; K. Togashi; T. Shiina

  SCIENTIFIC REPORTS, Feb. 2017, Peer-reviewed

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• 乳癌診断予測に有望である血清中IgG Fc N型糖鎖の安定性について

  川口 展子; 川島 雅央; 常盤 麻里子; 鈴木 栄治; 戸井 雅和

  日本乳癌学会総会プログラム抄録集, Jul. 2017

  
• Abstract P2-10-12: Relationship between predicted risks of carrying breast cancer susceptibility genes and the presence of germline variants in Japanese patients with primary breast cancer

  Noriko Senda; Nobuko Kawaguchi-Sakita; Masahiro Kawashima; Yukiko Inagaki-Kawata; Kenichi Yoshida; Tomomi Nishimura; Masahiro Takada; Eiji Suzuki; Yuki Kataoka; Fumiaki Sato; Yoshiaki Matsumoto; Masae Torii; Hiroshi Yoshibayashi; Kazuhiro Yamagami; Shigeru Tsuyuki; Akira Yamauchi; Nobuhiko Shinkura; Hironori Kato; Yoshio Moriguchi; Ryuji Okamura; Norimichi Kan; Hirofumi Suwa; Shingo Sakata; Susumu Mashima; Fumiaki Yotsumoto; Tsuyoshi Tachibana; Mitsuru Tanaka; Takashi Inamoto; Masahiro Sugimoto; Seishi Ogawa; Masakazu Toi

  Poster Session Abstracts, 15 Feb. 2020, Peer-reviewed

  
• Efficacy of Metformin in Patients With Breast Cancer Receiving Chemotherapy or Endocrine Therapy: Systematic Review and Meta-analysis.

  Kayoko Morio; Yasuko Kurata; Nobuko Kawaguchi-Sakita; Akihiro Shiroshita; Yuki Kataoka

  The Annals of pharmacotherapy, Mar. 2022

  
• Optimization of prediction methods for risk assessment of pathogenic germline variants in the Japanese population.

  Noriko Senda; Nobuko Kawaguchi-Sakita; Masahiro Kawashima; Yukiko Inagaki-Kawata; Kenichi Yoshida; Masahiro Takada; Masako Kataoka; Masae Torii; Tomomi Nishimura; Kosuke Kawaguchi; Eiji Suzuki; Yuki Kataoka; Yoshiaki Matsumoto; Hiroshi Yoshibayashi; Kazuhiko Yamagami; Shigeru Tsuyuki; Sachiko Takahara; Akira Yamauchi; Nobuhiko Shinkura; Hironori Kato; Yoshio Moriguchi; Ryuji Okamura; Norimichi Kan; Hirofumi Suwa; Shingo Sakata; Susumu Mashima; Fumiaki Yotsumoto; Tsuyoshi Tachibana; Mitsuru Tanaka; Kaori Togashi; Hironori Haga; Takahiro Yamada; Shinji Kosugi; Takashi Inamoto; Masahiro Sugimoto; Seishi Ogawa; Masakazu Toi

  Cancer science, Aug. 2021

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• Kinetic information from dynamic contrast-enhanced MRI enables prediction of residual cancer burden and prognosis in triple-negative breast cancer: a retrospective study.

  Ayane Yamaguchi; Maya Honda; Hiroshi Ishiguro; Masako Kataoka; Tatsuki R Kataoka; Hanako Shimizu; Masae Torii; Yukiko Mori; Nobuko Kawaguchi-Sakita; Kentaro Ueno; Masahiro Kawashima; Masahiro Takada; Eiji Suzuki; Yuji Nakamoto; Kosuke Kawaguchi; Masakazu Toi

  Scientific reports, 12 May 2021

  
• Pronociceptive Roles of Schwann Cell-Derived Galectin-3 in Taxane-Induced Peripheral Neuropathy.

  Madoka Koyanagi; Satoshi Imai; Mayuna Matsumoto; Yoko Iguma; Nobuko Kawaguchi-Sakita; Takeshi Kotake; Yuki Iwamitsu; Mpumelelo Ntogwa; Ren Hiraiwa; Kazuki Nagayasu; Mamiko Saigo; Takashi Ogihara; Atsushi Yonezawa; Tomohiro Omura; Shunsaku Nakagawa; Takayuki Nakagawa; Kazuo Matsubara

  Cancer research, 15 Apr. 2021

  
• Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants.

  Yukiko Inagaki-Kawata; Kenichi Yoshida; Nobuko Kawaguchi-Sakita; Masahiro Kawashima; Tomomi Nishimura; Noriko Senda; Yusuke Shiozawa; Yasuhide Takeuchi; Yoshikage Inoue; Aiko Sato-Otsubo; Yoichi Fujii; Yasuhito Nannya; Eiji Suzuki; Masahiro Takada; Hiroko Tanaka; Yuichi Shiraishi; Kenichi Chiba; Yuki Kataoka; Masae Torii; Hiroshi Yoshibayashi; Kazuhiko Yamagami; Ryuji Okamura; Yoshio Moriguchi; Hironori Kato; Shigeru Tsuyuki; Akira Yamauchi; Hirofumi Suwa; Takashi Inamoto; Satoru Miyano; Seishi Ogawa; Masakazu Toi

  Communications biology, 16 Oct. 2020

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• Incidence, features, and prognosis of immune-related adverse events involving the thyroid gland induced by nivolumab.

  Ichiro Yamauchi; Akihiro Yasoda; Shigemi Matsumoto; Yuichi Sakamori; Young Hak Kim; Motoo Nomura; Atsushi Otsuka; Toshinari Yamasaki; Ryoichi Saito; Morimasa Kitamura; Toshio Kitawaki; Masakatsu Hishizawa; Nobuko Kawaguchi-Sakita; Toshihito Fujii; Daisuke Taura; Masakatsu Sone; Nobuya Inagaki

  PloS one, 2019

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• Real-time navigation system for sentinel lymph node biopsy in breast cancer patients using projection mapping with indocyanine green fluorescence.

  Masahiro Takada; Megumi Takeuchi; Eiji Suzuki; Fumiaki Sato; Yoshiaki Matsumoto; Masae Torii; Nobuko Kawaguchi-Sakita; Hiroto Nishino; Satoru Seo; Etsuro Hatano; Masakazu Toi

  Breast cancer (Tokyo, Japan), Nov. 2018

  
• Vascular branching point counts using photoacoustic imaging in the superficial layer of the breast: A potential biomarker for breast cancer.

  Iku Yamaga; Nobuko Kawaguchi-Sakita; Yasufumi Asao; Yoshiaki Matsumoto; Aya Yoshikawa; Toshifumi Fukui; Masahiro Takada; Masako Kataoka; Masahiro Kawashima; Elham Fakhrejahani; Shotaro Kanao; Yoshie Nakayama; Mariko Tokiwa; Masae Torii; Takayuki Yagi; Takaki Sakurai; Hironori Haga; Kaori Togashi; Tsuyoshi Shiina; Masakazu Toi

  Photoacoustics, Sep. 2018

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• Serum immunoglobulin G Fc region N-glycosylation profiling by matrix-assisted laser desorption/ionization mass spectrometry can distinguish breast cancer patients from cancer-free controls.

  Nobuko Kawaguchi-Sakita; Kaoru Kaneshiro-Nakagawa; Masahiro Kawashima; Masahiro Sugimoto; Mariko Tokiwa; Eiji Suzuki; Shigeki Kajihara; Yuichiro Fujita; Shinichi Iwamoto; Koichi Tanaka; Masakazu Toi

  Biochemical and biophysical research communications, 22 Jan. 2016

  
• High-resolution imaging mass spectrometry reveals detailed spatial distribution of phosphatidylinositols in human breast cancer.

  Masahiro Kawashima; Noriko Iwamoto; Nobuko Kawaguchi-Sakita; Masahiro Sugimoto; Takayuki Ueno; Yoshiki Mikami; Kazuya Terasawa; Taka-Aki Sato; Koichi Tanaka; Kazuharu Shimizu; Masakazu Toi

  Cancer science, Oct. 2013

  
• Alterations of circulating endothelial cell and endothelial progenitor cell counts around the ovulation.

  Sunao Tanaka; Takayuki Ueno; Fumiaki Sato; Yoshitsugu Chigusa; Nobuko Kawaguchi-Sakita; Masahiro Kawashima; Noriyoshi Fujisawa; Kenichi Yoshimura; Satoshi Teramukai; Hiroshi Fujiwara; Masatoshi Fujita; Masakazu Toi

  The Journal of clinical endocrinology and metabolism, Nov. 2012

  
• Prognostic significance of tumor/stromal caveolin-1 expression in breast cancer patients.

  Niansong Qian; Takayuki Ueno; Nobuko Kawaguchi-Sakita; Masahiro Kawashima; Noriyuki Yoshida; Yoshiki Mikami; Tomoko Wakasa; Masayuki Shintaku; Shigeru Tsuyuki; Takashi Inamoto; Masakazu Toi

  Cancer science, Aug. 2011

  
• Sinisan, a traditional Chinese medicine, attenuates experimental chronic pancreatitis induced by trinitrobenzene sulfonic acid in rats.

  Yu Tang; Yonghui Liao; Nobuko Kawaguchi-Sakita; Vikram Raut; Elham Fakhrejahani; Niansong Qian; Masakazu Toi

  Journal of hepato-biliary-pancreatic sciences, Jul. 2011

  

Misc.

• 悪性リンパ腫に重複した乳癌腋窩リンパ節転移の一例

  岡田 有紀; 鈴木 栄治; 小味 由里絵; 石井 慧; 波々伯部; 絵里; 松本 純明; 川島 雅央; 鳥井 雅恵; 川口 展子; 高田 正泰; 竹内 恵; 佐藤 史顕; 戸井 雅和; 片岡 竜貴

  日本乳癌学会総会プログラム抄録集, May 2018

  
• ホルモン補充療法中のTurner症候群に発症した乳癌の一例

  波々伯部; 絵理; 戸井 雅和; 竹内 恵; 鈴木 栄治; 高田 正泰; 佐藤 史顕; 鳥井 雅恵; 吉川 伊津美; 川口 展子; 松本 純明; 川島 雅央; 石井 慧; 小味 由里絵; 岡田 有紀

  日本乳癌学会総会プログラム抄録集, May 2018

  
• PALB2遺伝子変異による遺伝性乳癌9例に関する検討

  樋上明音; 川口展子; 仙田典子; 川田有希子; 村上裕美; 本田明夏; 山田崇弘; 吉田健一; 橘強; 山上和彦; 露木茂; 岡村隆仁; 小杉眞司; 小川誠司; 戸井雅和

  日本癌治療学会学術集会(Web), 2020

  
• Development of photoacoustic vascular imaging system for breast cancer

  M. Toi; Y. Asao; M. Takada; M. Kataoka; T. Endo; M. Kawashima; I. Yamaga; Y. Nakayama; M. Tokiwa; E. Fakhrejahani; M. Torii; N. Kawaguchi-Sakita; S. Kanao; Y. Matsumoto; T. Yagi; T. Sakurai; K. Togashi; T. Shiina

  CANCER RESEARCH, Feb. 2017

  
• High-resolution MALDI imaging mass spectrometry demonstrated the correlation between phosphatidylinositol profiles and invasion/metastasis in human breast cancer

  Kawashima Masahiro; Kawaguchi-Sakita Nobuko; Sugimoto Masahiro; Sato Taka-Aki; Tanaka Koichi; Toi Masakazu

  CANCER RESEARCH, 01 Oct. 2014, Peer-reviewed

  
• MALDI-MSによる血清IgG Fc領域のN型糖鎖修飾プロファイリングを用いた乳がんの予測モデルの開発

  川口 展子; 中川 薫; 川島 雅央; 杉本 昌弘; 常盤 麻里子; 梶原 茂樹; 藤田 雄一郎; 岩本 慎一; 戸井 雅和; 田中 耕一

  日本癌学会総会記事, Oct. 2016

  
• The long-lasting anti-tumor activity of cisplatin affecting the sustainable systemic immune alteration may improve distant-disease free survival of triple-negative breast cancer in patients with a substantial residual tumor following preoperative chemotherapy: A retrospective analysis with translational research.

  Ayane Yamaguchi; Kosuke Kawaguchi; Hiroshi Ishiguro; Tatsuki R. Kataoka; Masae Torii; Chenfeng He; Nobuko Kawaguchi-Sakita; Masahiro Kawashima; Masahiro Takada; Eiji Suzuki; Masakazu Toi

  JOURNAL OF CLINICAL ONCOLOGY, May 2020

  
• High resolution imaging mass spectrometry reveals the breast cancer cell-related profiles of phosphatidylinositol unsaturation

  Masahiro Kawashima; Noriko Iwamoto; Nobuko Kawaguchi-Sakita; Masahiro Sugimoto; Takayuki Ueno; Kazuya Terasawa; Taka-Aki Sato; Koichi Tanaka; Kazuharu Shimizu; Masakazu Toi

  CANCER RESEARCH, Apr. 2013

  
• Nuclear localization of S6K is associated with unfavorable disease-free survival in hormone-receptor positive breast cancer cases

  Nobuko Kawaguchi-Sakita; Rafaat Abd El-Aal Bakheet Mohamed; Fumiaki Sato; Takayuki Ueno; Masahiro Kawashima; Noriyuki Yoshida; Wen Zhao Li; Tomoharu Suaie; Yoshiki Mikami; Shigehira Saji; Takashi Inamoto; Masakazu Toi

  CANCER RESEARCH, Apr. 2013

  
• 薬物療法マネージメントのこつ 化学療法誘発性末梢神経障害 本邦の現状とASCO/ESMOガイドライン2020

  川口 展子

  Cancer Board of the Breast, Mar. 2022

  
• 【がんゲノム医療-網羅的解析からの知見と臨床応用の展望】固形腫瘍の網羅的なゲノム解析と分子標的 乳がんの遺伝子解析に基づく治療戦略

  中川 梨恵; 川口 展子; 戸井 雅和

  医学のあゆみ, Oct. 2020

  
• 【乳癌学-最新の診断と治療-】乳癌の治療 乳癌の薬物療法と支持療法 乳癌の抗HER2療法 抗HER2療法に伴う副作用とその対策

  眞鍋 恵理子; 川口 展子; 石黒 洋

  日本臨床, Apr. 2017

  
• 薬物療法マネージメントのこつ Cryotherapyによる副作用予防

  川口 展子; 石黒 洋

  Cancer Board of the Breast, Feb. 2017

  
• 【がん幹細胞と支持細胞を標的とする薬剤の開発】乳がんのがん幹細胞様集団を標的とする薬剤の開発

  川口 展子; 上野 貴之; 戸井 雅和

  最新医学, Mar. 2011

  
• 【広範囲 血液・尿化学検査免疫学的検査[第7版] その数値をどう読むか】プロスタノイド、サイトカイン、増殖因子、ケモカイン 血管内皮増殖因子(VEGF)

  川口 展子; 上野 貴之; 戸井 雅和

  日本臨床, Jul. 2010

  
• State of the ART 乳癌の幹細胞

  川口 展子; 上野 貴之; 戸井 雅和

  Cancer Board 乳癌, Oct. 2009

  

Awards

• 19 Oct. 2018

  The 56th annual meeting of Japan Society of Clinical Oncology, The 56th annual meeting of Japan Society of Clinical Oncology Exellent Abstruct Award

External funds: Kakenhi

• Medical Language Processing Platform for Clinical Use of Patient Texts

  Grant-in-Aid for Scientific Research (B)

  Basic Section 62010:Life, health and medical informatics-related

  Nara Institute of Science and Technology

  荒牧 英治

  From 01 Apr. 2021, To 31 Mar. 2024, Granted

  自然言語処理;医療情報学;臨床医学;医療言語処理;医療情報;患者コミュニケーション

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21H03543/
• 乳癌臨床検体を用いたホルモン治療耐性メカニズムの解明

  Grant-in-Aid for Early-Career Scientists

  Basic Section 55010:General surgery and pediatric surgery-related

  Kyoto University

  川口 展子

  From 01 Apr. 2020, To 31 Mar. 2024, Granted

  乳がん;ホルモン療法抵抗性;ホルモン受容体陽性乳癌

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K17549/
• Development of breast cancer predection model using IgGFc N-glycosylation

  Grant-in-Aid for Young Scientists (B)

  Kyoto University

  Nobuko Kawaguchi

  From 01 Apr. 2017, To 31 Mar. 2020, Project Closed

  乳癌;IgG糖鎖;診断予測モデル;バイオマーカー;血清IgGN型糖鎖;糖鎖;癌;トランスレーショナルリサーチ;免疫学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K16505/
• The development of a program to promote adherence to compression therapy in elderly patients with lower limb lymphedema.

  Grant-in-Aid for Scientific Research (C)

  Basic Section 58060:Clinical nursing-related

  Kyoto University

  井沢 知子

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  下肢リンパ浮腫;高齢がん患者;圧迫療法;アドヒアランス;ランダム化比較試験;リンパ浮腫;高齢者

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K10868/

External funds: others

• 弾性圧迫グローブ・ストッキングによる圧迫療法の化学療法起因性末梢神経障害予防効果を検討 する探索的な多施設共同ランダム化比較試験

  Japan Agency for Medical Research and Development

  From 01 Oct. 2018, To 31 Mar. 2021

  川口展子

Education

Student achievements: Awards

• Outstanding Award

  Sayaka　Matsudaira, The 58th Annual Meetings of Japan society of Clinical Oncology, 22 Oct. 2020
• Best Presentation Award

  Akane　Higami, The 58tu Annual Meetings of Japan Society of Clinical Oncology, 24 Oct. 2020

Student achievements: Papers

• Optimization of prediction methods for risk assessment of pathogenic germline variants in the Japanese population

  Senda N, Kawaguchi-Sakita N, Kawashima M, Inagaki-Kawata Y, Yoshida K, Takada M, Kataoka M, Torii M, Nishimura T, Kawaguchi K, Suzuki E, Kataoka Y, Matsumoto Y, Yoshibayashi H, Yamagami K, Tsuyuki S, Takahara S, Yamauchi A, Shinkura N, Kato H, Moriguchi Y, Okamura R, Kan N, Suwa H, Sakata S, Mashima S, Yotsumoto F, Tachibana T, Tanaka M, Togashi K, Haga H, Yamada T, Kosugi S, Inamoto T, Sugimoto M, Ogawa S, Toi M.

  28 Jun. 2021, Cancer Sci., 112, 8, 3338, 3348, Peer-reviewed, English, Scientific journal

  https://doi.org/doi: 10.1111/cas.14986.
• Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants.

  Inagaki-Kawata Y, Yoshida K, Kawaguchi-Sakita N, Kawashima M, Nishimura T, Senda N, Shiozawa Y, Takeuchi Y, Inoue Y, Sato-Otsubo A, Fujii Y, Nannya Y, Suzuki E, Takada M, Tanaka H, Shiraishi Y, Chiba K, Kataoka Y, Torii M, Yoshibayashi H, Yamagami K, Okamura R, Moriguchi Y, Kato H, Tsuyuki S, Yamauchi A, Suwa H, Inamoto T, Miyano S, Ogawa S, Toi M

  16 Oct. 2020, Commun Biol., 3, 1, 578, Peer-reviewed

  https://doi.org/doi: 10.1038/s42003-020-01301-9