Basic Information

Faculty

• Faculty of Medicine
• 医学部

Academic Degree

• 23 Mar. 2005

  京都大学博士（医学）
• 博士（医学）(京都大学)

Academic Resume (Graduate Schools)

• 京都大学, 大学院医学研究科博士課程眼科学専攻, 修了
• 京都大学, 大学院医学研究科博士課程眼科学専攻, 修了

Academic Resume (Undergraduate School/Majors)

• 京都大学, 医学部医学科, 卒業
• 京都大学, 医学部医学科, 卒業

High School

• High School

  洛南高等学校

Language of Instruction

• English

ID,URL

• J-Global ID

  201401018553779043

researchmap URL

• https://researchmap.jp/7000009571

Research

Research Topics, Overview of the research

• Research Topics

  Imaging research in macular diseases and retinal vascular diseases

• Overview of the research

  To investigate the cellular level pathology in retinal diseases　using adaptive optics fundus imaging.

Papers

• Efficacy of Photodynamic Therapy for Polypoidal Choroidal Vasculopathy Associated with and without Pachychoroid Phenotypes.

  Hata M; Tagawa M; Oishi A; Kawashima Y; Nakata I; Akagi-Kurashige Y; Yamashiro K; Ooto S; Tamura H; Miyata M; Miyake M; Ueda-Arakawa N; Takahashi A; Tsujikawa A

  Ophthalmology. Retina, Dec. 2019, Peer-reviewed

  
• Predictive Genes for the Prognosis of Central Serous Chorioretinopathy.

  Hosoda Y; Yamashiro K; Miyake M; Ooto S; Oishi A; Miyata M; Uji A; Khor CC; Wong TY; Tsujikawa A

  Ophthalmology. Retina, Nov. 2019, Peer-reviewed

  
• Branch Retinal Vein Occlusion: Treatment Outcomes According to the Retinal Nonperfusion Area, Clinical Subtype, and Crossing Pattern.

  Iida-Miwa Y; Muraoka Y; Iida Y; Ooto S; Murakami T; Suzuma K; Tsujikawa A

  Scientific reports, 25 Apr. 2019, Peer-reviewed

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• Four-Year Outcome of Aflibercept for Neovascular Age-Related Macular Degeneration and polypoidal choroidal vasculopathy.

  Nishikawa K; Oishi A; Hata M; Miyake M; Ooto S; Yamashiro K; Miyata M; Tamura H; Ueda-Arakawa N; Takahashi A; Kawashima Y; Tsujikawa A

  Scientific reports, 06 Mar. 2019, Peer-reviewed

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• Abnormal Outer Choroidal Vasculature in Amblyopia.

  Terada N; Miyata M; Muraoka Y; Hata M; Fujimoto M; Yokota S; Nakanishi H; Suda K; Yoshikawa M; Ooto S; Ohtsuki H; Tsujikawa A

  Journal of ophthalmology, 2019, Peer-reviewed

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• Segmentation of the Four-Layered Retinal Vasculature Using High-Resolution Optical Coherence Tomography Angiography Reveals the Microcirculation Unit.

  Muraoka Y; Uji A; Ishikura M; Iida Y; Ooto S; Tsujikawa A

  Investigative ophthalmology & visual science, Dec. 2018, Peer-reviewed

  
• Subretinal drusenoid deposits AKA pseudodrusen.

  Spaide RF; Ooto S; Curcio CA

  Survey of ophthalmology, Nov. 2018, Peer-reviewed

  
• Time-Course Change in Eye Shape and Development of Staphyloma in Highly Myopic Eyes.

  Tomotaka Wakazono; Kenji Yamashiro; Masahiro Miyake; Masayuki Hata; Manabu Miyata; Akihito Uji; Hideo Nakanishi; Akio Oishi; Hiroshi Tamura; Sotaro Ooto; Akitaka Tsujikawa

  Investigative ophthalmology & visual science, 01 Nov. 2018, Peer-reviewed

  
• Novel Predictors of Visual Outcome in Anti-VEGF Therapy for Myopic Choroidal Neovascularization Derived Using OCT Angiography.

  Hosoda Y; Miyata M; Uji A; Ooto S; Yamashiro K; Tamura H; Oishi A; Ueda-Arakawa N; Miyake M; Hata M; Muraoka Y; Takahashi A; Tsujikawa A

  Ophthalmology. Retina, Nov. 2018, Peer-reviewed

  
• Effect of Retinal Nonperfusion on Two-Year Outcomes of Ranibizumab Treatment for Eyes with Branch Retinal Vein Occlusion

  Tsujikawa Akitaka; Muraoka Yuki; Ooto Sotaro; Iida Yuto; Suzuma Kiyoshi; Murakami Tomoaki; Miyake Masahiro; Ghashut Rima; Iida-Miwa Yuko

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Jul. 2018, Peer-reviewed

  
• Association Between Aqueous VEGF Levels and Clinical Parameters in Ranibizumab Treatment for Eyes with Branch Retinal Vein Occlusion

  Miyake Masahiro; Muraoka Yuki; Takahashi Ayako; Iida-Miwa Yuko; Murakami Tomoaki; Ooto Sotaro; Ghashut Rima; Suzuma Kiyoshi; Tsujikawa Akitaka; Iida Yuto

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Jul. 2018, Peer-reviewed

  
• FIXATION STATUS AFTER RESOLUTION OF MACULAR EDEMA ASSOCIATED WITH BRANCH RETINAL VEIN OCCLUSION.

  Kogo T; Muraoka Y; Ooto S; Suzuma K; Murakami T; Iida Y; Iida-Miwa Y; Ghashut R; Miyata M; Tsujikawa A

  Retina (Philadelphia, Pa.), Jul. 2018, Peer-reviewed

  
• Five-year visual outcomes after anti-VEGF therapy with or without photodynamic therapy for polypoidal choroidal vasculopathy

  Manabu Miyata; Sotaro Ooto; Kenji Yamashiro; Hiroshi Tamura; Masayuki Hata; Naoko Ueda-Arakawa; Munemitsu Yoshikawa; Shogo Numa; Akitaka Tsujikawa

  British Journal of Ophthalmology, 06 Jun. 2018, Peer-reviewed

  
• Pachychoroid Geographic Atrophy: Clinical and Genetic Characteristics.

  Takahashi A; Ooto S; Yamashiro K; Tamura H; Oishi A; Miyata M; Hata M; Yoshikawa M; Yoshimura N; Tsujikawa A

  Ophthalmology. Retina, Apr. 2018, Peer-reviewed

  
• Association between Eye Shape and Myopic Traction Maculopathy in High Myopia.

  Tomotaka Wakazono; Kenji Yamashiro; Masahiro Miyake; Hideo Nakanishi; Akio Oishi; Sotaro Ooto; Akitaka Tsujikawa; Nagahisa Yoshimura

  Ophthalmology, Apr. 2016, Peer-reviewed

  
• Retinal Pigment Epithelial Atrophy in Neovascular Age-Related Macular Degeneration After Ranibizumab Treatment

  Yoshimasa Kuroda; Kenji Yamashiro; Akitaka Tsujikawa; Sotaro Ooto; Hiroshi Tamura; Akio Oishi; Hideo Nakanishi; Masahiro Miyake; Munemitsu Yoshikawa; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Jan. 2016, Peer-reviewed

  
• Evaluation of Photoreceptors in Bietti Crystalline Dystrophy with CYP4V2 Mutations Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Manabu Miyata; Sotaro Ooto; Ken Ogino; Norimoto Gotoh; Satoshi Morooka; Yukiko Makiyama; Tomoko Hasegawa; Masako Sugahara; Masayuki Hata; Kenji Yamashiro; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Jan. 2016, Peer-reviewed

  
• Cotton Wool Spots after Anti-Vascular Endothelial Growth Factor Therapy for Macular Edema Associated with Central Retinal Vein Occlusion

  Teruyo Kida; Akitaka Tsujikawa; Yuki Muraoka; Seiyo Harino; Rie Osaka; Tomoaki Murakami; Sotaro Ooto; Kiyoshi Suzuma; Seita Morishita; Masanori Fukumoto; Hiroyuki Suzuki; Tsunehiko Ikeda

  OPHTHALMOLOGICA, 2016, Peer-reviewed

  
• Foveal Damage Due to Subfoveal Hemorrhage Associated with Branch Retinal Vein Occlusion

  Yuki Muraoka; Akitaka Tsujikawa; Ayako Takahashi; Yuto Iida; Tomoaki Murakami; Sotaro Ooto; Kiyoshi Suzuma; Akihito Uji; Nagahisa Yoshimura

  PLOS ONE, Dec. 2015, Peer-reviewed

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• Pachychoroid neovasculopathy and age-related macular degeneration

  Masahiro Miyake; Sotaro Ooto; Kenji Yamashiro; Ayako Takahashi; Munemitsu Yoshikawa; Yumiko Akagi-Kurashige; Naoko Ueda-Arakawa; Akio Oishi; Hideo Nakanishi; Hiroshi Tamura; Akitaka Tsujikawa; Nagahisa Yoshimura

  SCIENTIFIC REPORTS, Nov. 2015, Peer-reviewed

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• Association Between Insufficient Photoreceptor Layer Plugging and Postoperative Visual Outcome in the Surgically Closed Macular Hole

  Yu Kawashima; Akihito Uji; Sotaro Ooto; Masanori Hangai; Yoshikatsu Hosoda; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Nov. 2015, Peer-reviewed

  
• Factors Associated with Recurrence of Age-Related Macular Degeneration after Anti-Vascular Endothelial Growth Factor Treatment

  Yoshimasa Kuroda; Kenji Yamashiro; Masahiro Miyake; Munemitsu Yoshikawa; Hideo Nakanishi; Akio Oishi; Hiroshi Tamura; Sotaro Ooto; Akitaka Tsujikawa; Nagahisa Yoshimura

  OPHTHALMOLOGY, Nov. 2015, Peer-reviewed

  
• Foveal Photoreceptor Deformation as a Significant Predictor of Postoperative Visual Outcome in Idiopathic Epiretinal Membrane Surgery

  Yoshikatsu Hosoda; Sotaro Ooto; Masanori Hangai; Akio Oishi; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Oct. 2015, Peer-reviewed

  
• MULTIMODAL VISUAL FUNCTION TESTING IN EYES WITH NONEXUDATIVE AGE-RELATED MACULAR DEGENERATION

  Sotaro Ooto; Mihoko Suzuki; Sritatath Vongkulsiri; Taku Sato; Richard F. Spaide

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Sep. 2015, Peer-reviewed

  
• MULTIMODAL VISUAL FUNCTION TESTING IN EYES WITH NONEXUDATIVE AGE-RELATED MACULAR DEGENERATION

  Sotaro Ooto; Mihoko Suzuki; Sritatath Vongkulsiri; Taku Sato; Richard F. Spaide

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Sep. 2015, Peer-reviewed

  
• Effects of age and blood pressure on the retinal arterial wall, analyzed using adaptive optics scanning laser ophthalmoscopy

  Shigeta Arichika; Akihito ' Uji; Sotaro Ooto; Yuki Muraoka; Nagahisa Yoshimura

  SCIENTIFIC REPORTS, Jul. 2015, Peer-reviewed

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• MULTIMODAL IMAGING FINDINGS AND MULTIMODAL VISION TESTING IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

  Taku Sato; Mihoko Suzuki; Sotaro Ooto; Richard F. Spaide

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Jul. 2015, Peer-reviewed

  
• One-Year Result of Aflibercept Treatment on Age-Related Macular Degeneration and Predictive Factors for Visual Outcome

  Akio Oishi; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Hiroshi Tamura; Hideo Nakanishi; Naoko Ueda-Arakawa; Masahiro Miyake; Yumiko Akagi-Kurashige; Masayuki Hata; Munemitsu Yoshikawa; Yoshimasa Kuroda; Ayako Takahashi; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, May 2015, Peer-reviewed

  
• Paravascular Inner Retinal Defect Associated With High Myopia or Epiretinal Membrane

  Yuki Muraoka; Akitaka Tsujikawa; Masayuki Hata; Kenji Yamashiro; Abdallah A. Ellabban; Ayako Takahashi; Hideo Nakanishi; Sotaro Ooto; Teruyo Tanabe; Nagahisa Yoshimura

  JAMA OPHTHALMOLOGY, Apr. 2015, Peer-reviewed

  
• Two-year visual outcome of polypoidal choroidal vasculopathy treated with photodynamic therapy combined with intravitreal injections of ranibizumab

  Masayuki Hata; Akitaka Tsujikawa; Masahiro Miyake; Kenji Yamashiro; Sotaro Ooto; Akio Oishi; Isao Nakata; Ayako Takahashi; Nagahisa Yoshimura

  GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, Feb. 2015, Peer-reviewed

  
• Two-year visual outcome of ranibizumab in typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy

  Masayuki Hata; Akitaka Tsujikawa; Masahiro Miyake; Kenji Yamashiro; Sotaro Ooto; Akio Oishi; Hideo Nakanishi; Ayako Takahashi; Nagahisa Yoshimura

  GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, Feb. 2015, Peer-reviewed

  
• Effects of Sex and Age on the Normal Retinal and Choroidal Structures on Optical Coherence Tomography

  Sotaro Ooto; Masanori Hangai; Nagahisa Yoshimura

  CURRENT EYE RESEARCH, Feb. 2015, Peer-reviewed

  
• Retinal Pigment Epithelial Tear After Intravitreal Aflibercept for Neovascular Age-Related Macular Degeneration

  Taku Sato; Sotaro Ooto; Mihoko Suzuki; Richard F. Spaide

  Ophthalmic Surgery Lasers & Imaging Retina, Jan. 2015, Peer-reviewed

  
• Retinal Hemorheologic Characterization of Early-Stage Diabetic Retinopathy Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Shigeta Arichika; Akihito Uji; Tomoaki Murakami; Noriyuki Unoki; Shin Yoshitake; Yoko Dodo; Sotaro Ooto; Kazuaki Miyamoto; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Dec. 2014, Peer-reviewed

  
• Efficacy of Intravitreal Injection of Aflibercept in Neovascular Age-Related Macular Degeneration With or Without Choroidal Vascular Hyperpermeability

  Masayuki Hata; Akio Oishi; Akitaka Tsujikawa; Kenji Yamashiro; Masahiro Miyake; Sotaro Ooto; Hiroshi Tamura; Hideo Nakanishi; Ayako Takahashi; Munemitsu Yoshikawa; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Dec. 2014, Peer-reviewed

  
• Dome-Shaped Macular Configuration: Longitudinal Changes in the Sclera and Choroid by Swept-Source Optical Coherence Tomography Over Two Years

  Abdallah A. Ellabban; Akitaka Tsujikawa; Yuki Muraoka; Kenji Yamashiro; Akio Oishi; Sotaro Ooto; Hideo Nakanishi; Yoshimasa Kuroda; Masayuki Hata; Ayako Takahashi; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Nov. 2014, Peer-reviewed

  
• The Lack of Concordance Between Subretinal Drusenoid Deposits and Large Choroidal Blood Vessels

  Sritatath Vongkulsiri; Sotaro Ooto; Sarah Mrejen; Mihoko Suzuki; Richard F. Spaide

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Oct. 2014, Peer-reviewed

  
• Vitrectomy with Inner Retinal Fenestration for Optic Disc Pit Maculopathy

  Sotaro Ooto; Robert A. Mittra; Miriam E. Ridley; Richard F. Spaide

  OPHTHALMOLOGY, Sep. 2014, Peer-reviewed

  
• High-Resolution Imaging of Photoreceptors in Macular Microholes

  Sotaro Ooto; Masanori Hangai; Kohei Takayama; Naoko Ueda-Arakawa; Yukiko Makiyama; Masaaki Hanebuchi; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Sep. 2014, Peer-reviewed

  
• Association of Focal Choroidal Excavation With Age-Related Macular Degeneration

  Yoshimasa Kuroda; Akitaka Tsujikawa; Sotaro Ooto; Kenji Yamashiro; Akio Oishi; Hideo Nakanishi; Kyoko Kumagai; Masayuki Hata; Shigeta Arichika; Abdallah A. Ellabban; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Sep. 2014, Peer-reviewed

  
• Outer Retinal Corrugations in Age-Related Macular Degeneration

  Sotaro Ooto; Sritatath Vongkulsiri; Taku Sato; Mihoko Suzuki; Christine A. Curcio; Richard F. Spaide

  JAMA OPHTHALMOLOGY, Jul. 2014, Peer-reviewed

  
• Retinal Microstructural Changes in Eyes With Resolved Branch Retinal Vein Occlusion: An Adaptive Optics Scanning Laser Ophthalmoscopy Study

  Yumiko Akagi-Kurashige; Akitaka Tsujikawa; Sotaro Ooto; Yukiko Makiyama; Yuki Muraoka; Kyoko Kumagai; Akihito Uji; Shigeta Arichika; Tomoaki Murakami; Kazuaki Miyamoto; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Jun. 2014, Peer-reviewed

  
• Macular Choroidal Thickness and Volume of Eyes With Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography

  Naoko Ueda-Arakawa; Sotaro Ooto; Abdallah A. Ellabban; Ayako Takahashi; Akio Oishi; Hiroshi Tamura; Kenji Yamashiro; Akitaka Tsujikawa; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, May 2014, Peer-reviewed

  
• Choroidal Neovascularization in Eyes With Choroidal Vascular Hyperpermeability

  Masahiro Miyake; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Akio Oishi; Hiroshi Tamura; Isao Nakata; Fumihiko Matsuda; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, May 2014, Peer-reviewed

  
• Cone Abnormalities in Fundus Albipunctatus Associated With RDH5 Mutations Assessed Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Yukiko Makiyama; Sotaro Ooto; Masanori Hangai; Ken Ogino; Norimoto Gotoh; Akio Oishi; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Mar. 2014, Peer-reviewed

  
• Multimodal evaluation of macular function in age-related macular degeneration

  Ken Ogino; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Akio Oishi; Isao Nakata; Masahiro Miyake; Ayako Takahashi; Abdallah A. Ellabban; Nagahisa Yoshimura

  JAPANESE JOURNAL OF OPHTHALMOLOGY, Mar. 2014, Peer-reviewed

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• Adaptive Optics-Assisted Identification of Preferential Erythrocyte Aggregate Pathways in the Human Retinal Microvasculature

  Shigeta Arichika; Akihito Uji; Sotaro Ooto; Kazuaki Miyamoto; Nagahisa Yoshimura

  PLOS ONE, Feb. 2014, Peer-reviewed

  
• Reduction of Retinal Sensitivity in Eyes With Reticular Pseudodrusen

  Sotaro Ooto; Abdallah A. Ellabban; Naoko Ueda-Arakawa; Akio Oishi; Hiroshi Tamura; Kenji Yamashiro; Akitaka Tsujikawa; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Dec. 2013, Peer-reviewed

  
• Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration

  Akihito Uji; Sotaro Ooto; Masanori Hangai; Shigeta Arichika; Nagahisa Yoshimura

  PLoS ONE, 12 Nov. 2013, Peer-reviewed

  
• Macular Cone Abnormalities in Retinitis Pigmentosa with Preserved Central Vision Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Yukiko Makiyama; Sotaro Ooto; Masanori Hangai; Kohei Takayama; Akihito Uji; Akio Oishi; Ken Ogino; Satoko Nakagawa; Nagahisa Yoshimura

  PLOS ONE, Nov. 2013, Peer-reviewed

  
• Focal choroidal excavation in eyes with central serous chorioretinopathy

  Abdallah A. Ellabban; Akitaka Tsujikawa; Sotaro Ooto; Kenji Yamashiro; Akio Oishi; Isao Nakata; Masahiro Miyake; Yumiko Akagi-Kurashige; Naoko Ueda-Arakawa; Shigeta Arichika; Shin Yoshitake; Ayako Takahashi; Nagahisa Yoshimura

  American Journal of Ophthalmology, Oct. 2013, Peer-reviewed

  
• Comparison of Cone Pathologic Changes in Idiopathic Macular Telangiectasia Types 1 and 2 Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Sotaro Ooto; Masanori Hangai; Kohei Takayama; Naoko Ueda-Arakawa; Akitaka Tsujikawa; Kenji Yamashiro; Akio Oishi; Masaaki Hanebuchi; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Jun. 2013, Peer-reviewed

  
• LOCAL BIOMETRIC FEATURES AND VISUAL PROGNOSIS AFTER SURGERY FOR TREATMENT OF MYOPIC FOVEOSCHISIS

  Yuto Iida; Masanori Hangai; Munemitsu Yoshikawa; Sotaro Ooto; Nagahisa Yoshimura

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Jun. 2013, Peer-reviewed

  
• High-penetration optical coherence tomography and enhanced depth imaging in presumed retinal pigment epithelial hamartoma

  Ayako Takahashi; Sotaro Ooto; Nagahisa Yoshimura

  Retinal Cases and Brief Reports, Jun. 2013, Peer-reviewed

  
• Features and surgical outcome of retinal nerve fiber layer alterations associated with epiretinal membrane

  Yoko Ozeki-Jingami; Sotaro Ooto; Masanori Hangai; Akitaka Tsujikawa; Nagahisa Yoshimura

  Retinal Cases and Brief Reports, Jun. 2013, Peer-reviewed

  
• High-Resolution Imaging of Retinal Nerve Fiber Bundles in Glaucoma Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Kohei Takayama; Sotaro Ooto; Masanori Hangai; Naoko Ueda-Arakawa; Sachiko Yoshida; Tadamichi Akagi; Hanako Ohashi Ikeda; Atsushi Nonaka; Masaaki Hanebuchi; Takashi Inoue; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, May 2013, Peer-reviewed

  
• Intravitreal injection of ranibizumab for recovery of macular function in eyes with subfoveal polypoidal choroidal vasculopathy.

  Ogino K; Tsujikawa A; Yamashiro K; Ooto S; Oishi A; Nakata I; Miyake M; Yoshimura N

  Investigative ophthalmology & visual science, May 2013, Peer-reviewed

  
• Objective Assessment of Foveal Cone Loss Ratio in Surgically Closed Macular Holes Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Satoshi Yokota; Sotaro Ooto; Masanori Hangai; Kohei Takayama; Naoko Ueda-Arakawa; Yuki Yoshihara; Masaaki Hanebuchi; Nagahisa Yoshimura

  PLOS ONE, May 2013, Peer-reviewed

  
• Two-year outcome of photodynamic therapy combined with intravitreal injection of bevacizumab and triamcinolone acetonide for polypoidal choroidal vasculopathy

  Isao Nakata; Akitaka Tsujikawa; Kenji Yamashiro; Atsushi Otani; Sotaro Ooto; Yumiko Akagi-Kurashige; Naoko Ueda-Arakawa; Daisuke Iwama; Nagahisa Yoshimura

  Graefe's Archive for Clinical and Experimental Ophthalmology, Apr. 2013, Peer-reviewed

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• THE TIME COURSE CHANGES OF CHOROIDAL NEOVASCULARIZATION IN ANGIOID STREAKS

  Satoko Nakagawa; Kenji Yamashiro; Akitaka Tsujikawa; Atsushi Otani; Hiroshi Tamura; Sotaro Ooto; Nagahisa Yoshimura

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Apr. 2013, Peer-reviewed

  
• Tomographic Features of Macula After Successful Macular Hole Surgery

  Kazuyuki Nukada; Masanori Hangai; Sotaro Ooto; Munemitsu Yoshikawa; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Apr. 2013, Peer-reviewed

  
• PHOTORECEPTOR OUTER SEGMENT ABNORMALITIES AND RETINAL SENSITIVITY IN ACUTE ZONAL OCCULT OUTER RETINOPATHY

  Tomotaka Wakazono; Sotaro Ooto; Masanori Hangai; Nagahisa Yoshimura

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Mar. 2013, Peer-reviewed

  
• SENSITIVITY AND SPECIFICITY OF DETECTING RETICULAR PSEUDODRUSEN IN MULTIMODAL IMAGING IN JAPANESE PATIENTS

  Naoko Ueda-Arakawa; Sotaro Ooto; Akitaka Tsujikawa; Kenji Yamashiro; Akio Oishi; Nagahisa Yoshimura

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Mar. 2013, Peer-reviewed

  
• Prevalence and Genomic Association of Reticular Pseudodrusen in Age-Related Macular Degeneration

  Naoko Ueda-Arakawa; Sotaro Ooto; Isao Nakata; Kenji Yamashiro; Akitaka Tsujikawa; Akio Oishi; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Feb. 2013, Peer-reviewed

  
• Three-Dimensional Tomographic Features of Dome-Shaped Macula by Swept-Source Optical Coherence Tomography

  Abdallah A. Ellabban; Akitaka Tsujikawa; Akiko Matsumoto; Kenji Yamashiro; Akio Oishi; Sotaro Ooto; Isao Nakata; Yumiko Akagi-Kurashige; Masahiro Miyake; Hussein S. Elnahas; Tarek M. Radwan; Khaled A. Zaky; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Feb. 2013, Peer-reviewed

  
• Long-term effect of intravitreal injection of anti-VEGF agent for visual acuity and chorioretinal atrophy progression in myopic choroidal neovascularization

  Akio Oishi; Kenji Yamashiro; Akitaka Tsujikawa; Sotaro Ooto; Hiroshi Tamura; Isao Nakata; Masahiro Miyake; Nagahisa Yoshimura

  Graefe's Archive for Clinical and Experimental Ophthalmology, Jan. 2013, Peer-reviewed

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• Noninvasive and direct monitoring of erythrocyte aggregates in human retinal microvasculature using adaptive optics scanning laser ophthalmoscopy

  Shigeta Arichika; Akihito Uji; Masanori Hangai; Sotaro Ooto; Nagahisa Yoshimura

  Investigative Ophthalmology and Visual Science, 2013, Peer-reviewed

  
• Visual prognosis of eyes with submacular hemorrhage associated with exudative age-related macular degeneration

  Naoko Ueda-Arakawa; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Hiroshi Tamura; Nagahisa Yoshimura

  JAPANESE JOURNAL OF OPHTHALMOLOGY, Nov. 2012, Peer-reviewed

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• Macular Choroidal Thickness Measured by Swept Source Optical Coherence Tomography in Eyes with Inferior Posterior Staphyloma

  Abdallah A. Ellabban; Akitaka Tsujikawa; Akiko Matsumoto; Kenji Yamashiro; Akio Oishi; Sotaro Ooto; Isao Nakata; Yumiko Akagi-Kurashige; Masahiro Miyake; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Nov. 2012, Peer-reviewed

  
• RETINAL STRUCTURAL ALTERATIONS AND MACULAR SENSITIVITY IN IDIOPATHIC MACULAR TELANGIECTASIA TYPE 1

  Kohei Takayama; Sotaro Ooto; Hiroshi Tamura; Kenji Yamashiro; Atsushi Otani; Akitaka Tsujikawa; Nagahisa Yoshimura

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Oct. 2012, Peer-reviewed

  
• Three-beam spectral-domain optical coherence tomography for retinal imaging

  Nobuhito Suehira; Sotaro Ooto; Masanori Hangai; Kazuhiro Matsumoto; Nobuhiro Tomatsu; Takashi Yuasa; Kazuro Yamada; Nagahisa Yoshimura

  JOURNAL OF BIOMEDICAL OPTICS, Oct. 2012, Peer-reviewed

  
• Association of ARMS2 Genotype With Bilateral Involvement of Exudative Age-Related Macular Degeneration

  Hiroshi Tamura; Akitaka Tsujikawa; Kenji Yamashiro; Yumiko Akagi-Kurashige; Isao Nakata; Hideo Nakanishi; Hisako Hayashi; Sotaro Ooto; Atsushi Otani; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Sep. 2012, Peer-reviewed

  
• Relationship between retinal morphological findings and visual function in age-related macular degeneration

  Yumiko Akagi-Kurashige; Akitaka Tsujikawa; Akio Oishi; Sotaro Ooto; Kenji Yamashiro; Hiroshi Tamura; Isao Nakata; Naoko Ueda-Arakawa; Nagahisa Yoshimura

  GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, Aug. 2012, Peer-reviewed

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• Assessment of Macular Choroidal Thickness by Optical Coherence Tomography and Angiographic Changes in Central Serous Chorioretinopathy

  Pichai Jirarattanasopa; Sotaro Ooto; Akitaka Tsujikawa; Kenji Yamashiro; Masanori Hangai; Masaya Hirata; Akiko Matsumoto; Nagahisa Yoshimura

  OPHTHALMOLOGY, Aug. 2012, Peer-reviewed

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• Oximetry of Retinal Capillaries by Multicomponent Analysis

  Hiromitsu Furukawa; Hidenobu Arimoto; Tomohiro Shirai; Sotaro Ooto; Masanori Hangai; Nagahisa Yoshimura

  APPLIED SPECTROSCOPY, Aug. 2012, Peer-reviewed

  
• Factors Associated With the Response of Age-Related Macular Degeneration to Intravitreal Ranibizumab Treatment

  Kenji Yamashiro; Kaoruko Tomita; Akitaka Tsujikawa; Isao Nakata; Yumiko Akagi-Kurashige; Masahiro Miyake; Sotaro Ooto; Hiroshi Tamura; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Jul. 2012, Peer-reviewed

  
• Photoreceptor Damage and Foveal Sensitivity in Surgically Closed Macular Holes: An Adaptive Optics Scanning Laser Ophthalmoscopy Study

  Sotaro Ooto; Masanori Hangai; Kohei Takayama; Naoko Ueda-Arakawa; Masaaki Hanebuchi; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Jul. 2012, Peer-reviewed

  
• Choroidal thickness after intravitreal ranibizumab injections for choroidal neovascularization

  Abdallah A Ellabban; Akitaka Tsujikawa; Ken Ogino; Sotaro Ooto; Kenji Yamashiro; Akio Oishi; Nagahisa Yoshimura

  Clinical Ophthalmology, 02 Jun. 2012, Peer-reviewed

  
• Macular Choroidal Thickness and Volume in Eyes With Angioid Streaks Measured by Swept Source Optical Coherence Tomography

  Abdallah A. Ellabban; Akitaka Tsujikawa; Akiko Matsumoto; Ken Ogino; Masanori Hangai; Sotaro Ooto; Kenji Yamashiro; Masahiro Akiba; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Jun. 2012, Peer-reviewed

  
• Choroidal Thickness, Vascular Hyperpermeability, and Complement Factor H in Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy

  Pichai Jirarattanasopa; Sotaro Ooto; Isao Nakata; Akitaka Tsujikawa; Kenji Yamashiro; Akio Oishi; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Jun. 2012, Peer-reviewed

  
• In Vivo Imaging of Lamina Cribrosa Pores by Adaptive Optics Scanning Laser Ophthalmoscopy

  Tadamichi Akagi; Masanori Hangai; Kohei Takayama; Atsushi Nonaka; Sotaro Ooto; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Jun. 2012, Peer-reviewed

  
• Automated Assessment of Drusen Using Three-Dimensional Spectral-Domain Optical Coherence Tomography

  Daisuke Iwama; Masanori Hangai; Sotaro Ooto; Atsushi Sakamoto; Hideo Nakanishi; Takashi Fujimura; Amitha Domalpally; Ronald P. Danis; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Mar. 2012, Peer-reviewed

  
• High-Resolution Imaging of the Retinal Nerve Fiber Layer in Normal Eyes Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Kohei Takayama; Sotaro Ooto; Masanori Hangai; Naoko Arakawa; Susumu Oshima; Naohisa Shibata; Masaaki Hanebuchi; Takashi Inoue; Nagahisa Yoshimura

  PLOS ONE, Mar. 2012, Peer-reviewed

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• Treatment of Polypoidal Choroidal Vasculopathy With Photodynamic Therapy Combined With Intravitreal Injections of Ranibizumab

  Kaoruko Tomita; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Hiroshi Tamura; Atsushi Otani; Yoshihito Nakayama; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Jan. 2012, Peer-reviewed

  
• The Source of Moving Particles in Parafoveal Capillaries Detected by Adaptive Optics Scanning Laser Ophthalmoscopy

  Akihito Uji; Masanori Hangai; Sotaro Ooto; Kohei Takayama; Naoko Arakawa; Hiroshi Imamura; Koji Nozato; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Jan. 2012, Peer-reviewed

  
• Photoreceptor restoration in unilateral acute idiopathic maculopathy on adaptive optics scanning laser ophthalmoscopy.

  Ooto S; Hangai M; Yoshimura N

  Archives of ophthalmology (Chicago, Ill. : 1960), Dec. 2011, Peer-reviewed

  
• Effects of Age, Sex, and Axial Length on the Three-Dimensional Profile of Normal Macular Layer Structures

  Sotaro Ooto; Masanori Hangai; Atsuo Tomidokoro; Hitomi Saito; Makoto Araie; Tomohiro Otani; Shoji Kishi; Kenji Matsushita; Naoyuki Maeda; Motohiro Shirakashi; Haruki Abe; Shinji Ohkubo; Kazuhisa Sugiyama; Aiko Iwase; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Nov. 2011, Peer-reviewed

  
• Genetic Variants in Pigment Epithelium-Derived Factor Influence Response of Polypoidal Choroidal Vasculopathy to Photodynamic Therapy

  Isao Nakata; Kenji Yamashiro; Ryo Yamada; Norimoto Gotoh; Hideo Nakanishi; Hisako Hayashi; Akitaka Tsujikawa; Atsushi Otani; Sotaro Ooto; Hiroshi Tamura; Masaaki Saito; Kuniharu Saito; Tomohiro Iida; Akio Oishi; Yasuo Kurimoto; Fumihiko Matsuda; Nagahisa Yoshimura

  OPHTHALMOLOGY, Jul. 2011, Peer-reviewed

  
• Macular Choroidal Thickness and Volume in Normal Subjects Measured by Swept-Source Optical Coherence Tomography

  Masaya Hirata; Akitaka Tsujikawa; Akiko Matsumoto; Masanori Hangai; Sotaro Ooto; Kenji Yamashiro; Masahiro Akiba; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Jul. 2011, Peer-reviewed

  
• High-Resolution Photoreceptor Imaging in Idiopathic Macular Telangiectasia Type 2 Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Sotaro Ooto; Masanori Hangai; Kohei Takayama; Naoko Arakawa; Akitaka Tsujikawa; Hideki Koizumi; Susumu Oshima; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Jul. 2011, Peer-reviewed

  
• Association of Lesion Size and Visual Prognosis to Polypoidal Choroidal Vasculopathy

  Akitaka Tsujikawa; Yumiko Ojima; Kenji Yamashiro; Isao Nakata; Sotaro Ooto; Hiroshi Tamura; Hideo Nakanishi; Hisako Hayashi; Atsushi Otani; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Jun. 2011, Peer-reviewed

  
• High-Resolution Imaging of the Photoreceptor Layer in Epiretinal Membrane Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Sotaro Ooto; Masanori Hangai; Kohei Takayama; Atsushi Sakamoto; Akitaka Tsujikawa; Susumu Oshima; Takashi Inoue; Nagahisa Yoshimura

  OPHTHALMOLOGY, May 2011, Peer-reviewed

  
• Development of polypoidal lesions in age-related macular degeneration

  A. Tsujikawa; Y. Ojima; K. Yamashiro; S. Ooto; H. Tamura; I. Nakata; N. Yoshimura

  EYE, Apr. 2011, Peer-reviewed

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• RETINAL MICROSTRUCTURAL ABNORMALITIES IN CENTRAL SEROUS CHORIORETINOPATHY AND POLYPOIDAL CHOROIDAL VASCULOPATHY

  Sotaro Ooto; Akitaka Tsujikawa; Satoshi Mori; Hiroshi Tamura; Kenji Yamashiro; Atsushi Otani; Nagahisa Yoshimura

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Mar. 2011, Peer-reviewed

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• Prognostic factors for visual outcomes 2-years after intravitreal bevacizumab for myopic choroidal neovascularization

  H. Nakanishi; A. Tsujikawa; Y. Yodoi; Y. Ojima; A. Otani; H. Tamura; K. Yamashiro; S. Ooto; N. Yoshimura

  EYE, Mar. 2011, Peer-reviewed

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• INTRAOCULAR GAS DYNAMICS AFTER 20-GAUGE AND 23-GAUGE VITRECTOMY WITH SULFUR HEXAFLUORIDE GAS TAMPONADE

  Sentaro Kusuhara; Sotaro Ooto; Daisaku Kimura; Kyoko Itoi; Hirokazu Mukuno; Noriko Miyamoto; Masayuki Akimoto; Hitoshi Takagi

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Feb. 2011, Peer-reviewed

  
• Spectral-domain optical coherence tomography for three-dimensional visualization of the detached membrane in Valsalva retinopathy

  Tomoko Hasegawa; Sotaro Ooto; Nagahisa Yoshimura

  JAPANESE JOURNAL OF OPHTHALMOLOGY, Jan. 2011, Peer-reviewed

  
• Intravitreal bevacizumab for type 1 idiopathic macular telangiectasia

  K. Takayama; S. Ooto; H. Tamura; K. Yamashiro; A. Otani; A. Tsujikawa; N. Yoshimura

  EYE, Sep. 2010, Peer-reviewed

  
• High-Resolution Imaging of Resolved Central Serous Chorioretinopathy Using Adaptive Optics Scanning Laser Ophthalmoscopy

  Sotaro Ooto; Masanori Hangai; Atsushi Sakamoto; Akitaka Tsujikawa; Kenji Yamashiro; Yumiko Ojima; Yoshihiko Yamada; Hideo Mukai; Susumu Oshima; Takashi Inoue; Nagahisa Yoshimura

  OPHTHALMOLOGY, Sep. 2010, Peer-reviewed

  
• Thickness of photoreceptor layers in polypoidal choroidal vasculopathy and central serous chorioretinopathy

  Sotaro Ooto; Akitaka Tsujikawa; Satoshi Mori; Hiroshi Tamura; Kenji Yamashiro; Nagahisa Yoshimura

  GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, Aug. 2010, Peer-reviewed

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• Relationship between retinal sensitivity and morphologic changes in eyes with confluent soft drusen

  Daisuke Iwama; Akitaka Tsujikawa; Yumiko Ojima; Hideo Nakanishi; Kenji Yamashiro; Hiroshi Tamura; Sotaro Ooto; Nagahisa Yoshimura

  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, Jul. 2010, Peer-reviewed

  
• Treatment of polypoidal choroidal vasculopathy by intravitreal injection of bevacizumab

  Akitaka Tsujikawa; Sotaro Ooto; Kenji Yamashiro; Hiroshi Tamura; Atsushi Otani; Nagahisa Yoshimura

  JAPANESE JOURNAL OF OPHTHALMOLOGY, Jul. 2010, Peer-reviewed

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• Macular hole formation following photodynamic therapy combined with intravitreal injection of bevacizumab and triamcinolone acetonide

  Daisuke Iwama; Sotaro Ooto; Akitaka Tsujikawa; Kenji Yamashiro; Nagahisa Yoshimura

  JAPANESE JOURNAL OF OPHTHALMOLOGY, Jul. 2010, Peer-reviewed

  
• PUNCTATE HYPERFLUORESCENT SPOTS ASSOCIATED WITH CENTRAL SEROUS CHORIORETINOPATHY AS SEEN ON INDOCYANINE GREEN ANGIOGRAPHY

  Akitaka Tsujikawa; Yumiko Ojima; Kenji Yamashiro; Sotaro Ooto; Hiroshi Tamura; Satoko Nakagawa; Nagahisa Yoshimura

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, May 2010, Peer-reviewed

  
• STERILE ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION OF BEVACIZUMAB OBTAINED FROM A SINGLE BATCH

  Kenji Yamashiro; Akitaka Tsujikawa; Kazuaki Miyamoto; Hideasu Oh; Atsushi Otani; Hiroshi Tamuara; Sotaro Ooto; Manabu Sasahara; Daisuke Iwama; Nagahisa Yoshimura

  RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Mar. 2010, Peer-reviewed

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• Prognostic Factors of Vitreous Hemorrhage Secondary to Exudative Age-Related Macular Degeneration

  Tomoko Hasegawa; Atsushi Otani; Manabu Sasahara; Norimoto Gotoh; Sotaro Ooto; Hiroshi Tamura; Kenji Yamashiro; Akitaka Tsujikawa; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Feb. 2010, Peer-reviewed

  
• Three-Dimensional Profile of Macular Retinal Thickness in Normal Japanese Eyes

  Sotaro Ooto; Masanori Hangai; Atsushi Sakamoto; Atsuo Tomidokoro; Makoto Araie; Tomohiro Otani; Shoji Kishi; Kenji Matsushita; Naoyuki Maeda; Motohiro Shirakashi; Haruki Abe; Hisashi Takeda; Kazuhisa Sugiyama; Hitomi Saito; Aiko Iwase; Nagahisa Yoshimura

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Jan. 2010, Peer-reviewed

  
• Restoration of outer segments of foveal photoreceptors after resolution of central serous chorioretinopathy

  Yumiko Ojima; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Hiroshi Tamura; Nagahisa Yoshimura

  JAPANESE JOURNAL OF OPHTHALMOLOGY, Jan. 2010, Peer-reviewed

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• Comparative Assessment of Photodynamic Therapy for Typical Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy: A Multicenter Study in Hyogo Prefecture, Japan

  Shigeru Honda; Hisanori Imai; Kenji Yamashiro; Yasuo Kurimoto; Noriko Kanamori-Matsui; Yasuaki Kagotani; Yasushi Tamura; Hiroyuki Yamamoto; Sotaro Ohoto; Hitoshi Takagi; Mamoru Uenishi; Akira Negi

  OPHTHALMOLOGICA, 2009, Peer-reviewed

  
• Suprachoroidal fluid as a complication of 23-gauge vitreous surgery

  S. Ooto; D. Kimura; K. Itoi; H. Mukuno; S. Kusuhara; N. Miyamoto; M. Akimoto; H. Takagi

  BRITISH JOURNAL OF OPHTHALMOLOGY, Oct. 2008, Peer-reviewed

  
• Outcomes of 23-and 25-gauge transconjunctival sutureless vitrectomies for idiopathic macular holes

  S. Kusuhara; S. Ooto; D. Kimura; K. Itoi; H. Mukuno; N. Miyamoto; M. Akimoto; S. Kuriyama; H. Takagi

  BRITISH JOURNAL OF OPHTHALMOLOGY, Sep. 2008, Peer-reviewed

  
• Identifying pathogenic genetic background of simplex or multiplex retinitis pigmentosa patients: a large scale mutation screening study

  Z-B Jin; M. Mandai; T. Yokota; K. Higuchi; K. Ohmori; F. Ohtsuki; S. Takakura; T. Itabashi; Y. Wada; M. Akimoto; S. Ooto; T. Suzuki; Y. Hirami; H. Ikeda; N. Kawagoe; A. Oishi; S. Ichiyama; M. Takahashi; N. Yoshimura; S. Kosugi

  JOURNAL OF MEDICAL GENETICS, Jul. 2008, Peer-reviewed

  
• Association between abnormal autofluorescence and photoreceptor disorganization in retinitis pigmentosa

  Tomoaki Murakami; Masayuki Akimoto; Sotaro Ooto; Takuya Suzuki; Hanako Ikeda; Naoaki Kawagoe; Masayo Takahashi; Nagahisa Yoshimura

  AMERICAN JOURNAL OF OPHTHALMOLOGY, Apr. 2008, Peer-reviewed

  
• Wnt signaling promotes regeneration in the retina of adult mammals

  Fumitaka Osakada; Sotaro Ooto; Tadamichi Akagi; Michiko Mandai; Akinori Akaike; Masayo Takahashi

  JOURNAL OF NEUROSCIENCE, Apr. 2007, Peer-reviewed

  
• Wnt signaling promotes retinal regeneration in adult mammals

  Fumitaka Osakada; Sotaro Ooto; Tadamichi Akagi; Michiko Mandai; Akinori Akaike; Masayo Takahashi

  NEUROSCIENCE RESEARCH, 2007, Peer-reviewed

  
• [Potential for neural regeneration in the adult mammalian retina].

  Ooto S

  Nippon Ganka Gakkai zasshi, Nov. 2006, Peer-reviewed

  
• Otx2 homeobox gene induces photoreceptor-specific phenotypes in cells derived from adult iris and ciliary tissue

  T Akagi; M Mandai; S Ooto; Y Hirami; F Osakada; R Kageyama; N Yoshimura; M Takahashi

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Dec. 2004, Peer-reviewed

  
• The role of estrogen and estrogen receptor beta in choroidal neovascularization

  M Tanemura; N Miyamoto; M Mandai; H Kamizuru; S Ooto; T Yasukawa; M Takahashi; Y Honda

  MOLECULAR VISION, Dec. 2004, Peer-reviewed

  
• Potential for neural regeneration after neurotoxic injury in the adult mammalian retina

  S Ooto; T Akagi; R Kageyama; J Akita; M Mandai; Y Honda; M Takahashi

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Sep. 2004, Peer-reviewed

  
• In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells

  M Haruta; Y Sasai; H Kawasaki; K Amemiya; S Ooto; M Kitada; H Suemori; N Nakatsuji; C Ide; Y Honda; M Takahashi

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Mar. 2004, Peer-reviewed

  
• Effects of prolonged delivery of brain-derived neurotrophic factor on the fate of neural stem cells transplanted into the developing rat retina

  T Suzuki; S Ooto; T Akagi; K Amemiya; R Igarashi; Y Mizushima; M Takahashi

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Oct. 2003, Peer-reviewed

  
• Induction of the differentiation of lentoids from primate embryonic stem cells

  S Ooto; M Haruta; Y Honda; H Kawasaki; Y Sasai; M Takahashi

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Jun. 2003, Peer-reviewed

  

Presentations

• 教育セミナー 網膜硝子体検査の撮りかた、見かた「OCT」

  大音 壮太郎

  第54回日本網膜硝子体学会総会, 06 Dec. 2015, Invited

  
• 次世代OCT: Spectralis OCT2の画像を読むVol.2

  大音 壮太郎

  第54回日本網膜硝子体学会, 04 Dec. 2015, Invited

  
• Pachychoroid neovasculopathyとAMD

  大音 壮太郎

  新・黄斑疾患個別化医療研究会, 03 Dec. 2015, Invited

  
• 網脈絡膜画像診断～黄斑疾患のOCT画像を読む～

  大音 壮太郎

  Ophthalmology Webカンファレンス, 04 Nov. 2015, Invited

  
• BRVOにおけるranibizumabによる網膜下出血の吸収と視力予後

  大音 壮太郎

  RVO Scientific advisory meeting, 03 Nov. 2015, Invited

  
• ドルーゼンと加齢黄斑変性

  大音 壮太郎

  第26回宮城眼科先端医療研究会, 30 Oct. 2015, Invited

  
• Spectralis OCT2/OCT angiographyの使用経験

  大音 壮太郎

  第2回Spectralisユーザーズセミナー, 24 Oct. 2015, Invited

  
• 次世代OCT Spectralis OCT2の画像を読む

  大音 壮太郎

  第69回日本臨床眼科学会, 24 Oct. 2015, Invited

  
• 網膜変性疾患の画像診断

  大音 壮太郎

  第48回神戸市立医療センター中央市民病院 眼科臨床懇話会, 03 Sep. 2015, Invited

  
• OCT 緑内障

  大音 壮太郎

  コメディカルセミナー, 12 Jul. 2015, Invited

  
• ドルーゼンと加齢黄斑変性

  大音 壮太郎

  第4回North Kato RETINA Club, 27 Jun. 2015, Invited

  
• ドルーゼンと加齢黄斑変性

  大音 壮太郎

  第73回埼玉眼科講習会, 12 Jun. 2015, Invited

  
• シンポジウム Imagingの最先端「AO-SLO」

  大音 壮太郎

  第4回日本視野学会学術集会, 30 May 2015, Invited

  
• RVO Medical

  大音 壮太郎

  第10回Ophthalmic Gallery眼科研究会, 23 May 2015, Invited

  
• シンポジウム 画像診断－垣根を越えて－「Adaptive Optics SLO」

  大音 壮太郎

  第119回日本眼科学会総会, 17 Apr. 2015

  
• ドルーゼンと加齢黄斑変性

  大音 壮太郎

  北摂地区眼科診療アップデートセミナー, 04 Feb. 2015, Invited

  
• Adaptive Optics SLO

  大音 壮太郎

  Japan Glaucoma Council 2014, 06 Dec. 2014, Invited

  
• 補償光学と黄斑疾患

  大音 壮太郎

  群馬県眼科医会学術講演会, 24 Oct. 2014, Invited

  
• シンポジウム 補償光学眼底検査アップデート「AO:OCTとの関係」

  大音 壮太郎

  第62回日本臨床視覚電気生理学会, 04 Oct. 2014

  
• ドルーゼンと加齢黄斑変性

  大音 壮太郎

  第45回岸和田市医師会眼科懇話会, 30 Aug. 2014, Invited

  
• AO-SLOを用いた網膜構造の評価

  大音 壮太郎

  2014シンポジウムシリーズ すばる望遠鏡から顕微鏡へ, 20 Aug. 2014, Invited

  
• ドルーゼンと加齢黄斑変性

  大音 壮太郎

  京都府眼科医会夏期集談会, 26 Jul. 2014, Invited

  
• ドルーゼンと加齢黄斑変性

  大音 壮太郎

  第125回北大阪眼科セミナー, 大阪, 19 Jun. 2014, Invited

  
• シンポジウム 最新緑内障検査機器のアップデート「Adaptive Optics SLOによる網膜神経線維束の可視化」

  大音 壮太郎

  第118回日本眼科学会総会, 03 Apr. 2014

  
• 教育セミナー 網膜硝子体の新しい検査法「AO-SLOによる視細胞の解析」

  大音 壮太郎

  第118回日本眼科学会総会, 03 Apr. 2014

  
• Adaptive Optics in Glaucoma

  Sotaro Ooto

  World Ophthalmology Conference, 02 Apr. 2014

  
• 眼底イメージング～OCTの読み方から補償光学技術まで～

  大音 壮太郎

  大阪赤十字眼科フォーラム, 09 Mar. 2013, Invited

  
• シンポジウム 眼光学から考える眼底イメージング「Adaptive Optics」

  大音 壮太郎

  第66回日本臨床眼科学会総会, 26 Oct. 2012

  
• SIG黄斑研究会 網膜形態評価法はどこまで進歩したか「補償光学 視細胞」

  大音 壮太郎

  第66回日本臨床眼科学会総会, 25 Oct. 2012

  
• 視機能研究会 画像は機能を推し量れるか「黄斑上膜における視細胞配列異常」

  大音 壮太郎

  第60回日本視覚電気生理学会総会, 06 Oct. 2012

  
• サブスペシャリティサンデー 後眼部疾患 網膜疾患：手術システム・診断機器の進歩「形態学的診断機器の進歩」

  大音 壮太郎

  第66回日本眼科学会総会, 08 Apr. 2012

  
• Adaptive Optics-a-state-of–the-art

  Sotaro Ooto

  EURETINA winter meeting, 28 Jan. 2012

  
• シンポジウム 網脈絡膜画像解析「補償光学」

  大音 壮太郎

  第47回日本眼光学学会総会, 03 Sep. 2011

  
• 教育セミナー 眼底画像診断の進歩「補償光学」

  大音 壮太郎

  第115回日本眼科学会総会, 12 May 2011

  
• シンポジウム 黄斑部毛細血管拡張症の病態と治療「AO-SLOによる視細胞異常所見」

  大音 壮太郎

  網膜2010（第49回日本網膜硝子体学会総会・第16回日本糖尿病眼学会総会）, 28 Nov. 2010

  
• 黄斑研究会 最先端の画像診断「Adaptive Optics SLO」

  大音 壮太郎

  第64回日本臨床眼科学会総会, 11 Nov. 2010

  
• シンポジウム 眼底画像診断のこれから「AO-SLOによる視細胞イメージング」

  大音 壮太郎

  第27回日本眼循環学会総会, 30 Jul. 2010

  

Awards

• 11 Oct. 2015

  Achievement Award(American Academy of Ophthalmology)
• 15 Apr. 2006

  日本眼科学会平成17年度学術奨励賞
• 29 Jul. 2011

  SILVER AWARD(わかもと先進眼科医療研究会)
• 24 Oct. 2012

  Alcon japan Hida Memorial Award(日本アルコン)
• 13 Oct. 2019

  Secretariat Award(American Academy of Ophthalmology)
• 07 Dec. 2013

  田野Young investigator’s Award(日本網膜硝子体学会)
• 2005

  Japanese Ophthalmological Society, Academic Encouragement Award
• 2011

  わかもと先進眼科医療会, WACAMOTO Silver Award
• 2012

  Alcon Japan, Alcon Japan Hida Memorial Award
• 2013

  Japanese Retina and Vitreous Society, Tano Young Investigator's Award
• 2015

  American Academy of Ophthalmology, Achievement Award
• 12 Oct. 2019

  American Academy of Ophthalmology, Secretariat Award

External funds: Kakenhi

• Pathological clarification and development of novel treatment in neovascular age-related macular degeneration using adaptive-optics optical coherence tomography

  Grant-in-Aid for Scientific Research (C)

  Basic Section 56060:Ophthalmology-related

  Kyoto University

  Manabu Miyata

  From 01 Apr. 2021, To 31 Mar. 2024, Project Closed

  加齢黄斑変性;長期視力予後;組織プラスミノゲンアクチベータ;アフリベルセプト;黄斑下血腫;補償光学OCT;滲出型加齢黄斑変性;イメージング;aflibercept;Muller細胞;黄斑下出血;補償光学走査型レーザー検眼鏡;長期視力経過;網膜色素上皮裂孔;補償光学;光干渉断層計

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K09716/
• Novel therapeutic targets regarding autoimmune neurodegeneration in diabetic retinopathy

  Grant-in-Aid for Scientific Research (C)

  Basic Section 56060:Ophthalmology-related

  Kyoto University

  Tomoaki Murakami

  From 01 Apr. 2020, To 31 Mar. 2023, Project Closed

  糖尿病網膜症;糖尿病黄斑虚血;網膜変性;細胞外小胞;細胞外ミトコンドリア;XRCC5, XRCC6;網膜色素上皮;糖尿病黄斑浮腫;自己免疫;橋渡し研究;微小小胞;神経変性;自己抗体;OCT angiography;抗fumarase抗体;抗hexokinase 1抗体;視細胞障害;光干渉断層計アンギオグラフィー;補体

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K09788/
• Pathology and treatment for dry age-related macular degeneration using adaptive optics OCT

  Grant-in-Aid for Scientific Research (C)

  Basic Section 56060:Ophthalmology-related

  Kyoto University

  Ooto Sotaro

  From 01 Apr. 2019, To 31 Mar. 2022, Project Closed

  加齢黄斑変性;視細胞;脈絡膜;OCT;補償光学;光干渉断層計

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K09948/
• Histopathological changes and their autoimmune mechanisms in chorioretinal diseases

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields

  Kyoto University

  Akitaka Tsujikawa

  From 29 Jun. 2018, To 31 Mar. 2020, Project Closed

  糖尿病網膜症;加齢黄斑変性;光干渉断層計アンギオグラフィー;抗VEGF療法;自己抗体;ゲノムワイドイド関連解析;補体;網膜静脈閉塞症;抗fumarase抗体;抗hexokinase 1抗体;視細胞障害;糖尿病黄斑浮腫;光干渉断層計;自己免疫

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K19610/
• Pathological clarification and development of novel treatment in age-related macular degeneration by a multiple approach

  Grant-in-Aid for Scientific Research (C)

  Basic Section 56060:Ophthalmology-related

  Kyoto University

  Manabu Miyata

  From 01 Apr. 2018, To 31 Mar. 2021, Project Closed

  加齢黄斑変性;ポリープ状脈絡膜血管症;光線力学療法;抗VEGF療法;パキコロイド;光干渉断層計;イメージング;脈絡膜新生血管;OCT angiography;強度近視;長期経過;脈絡毛細血管板;網膜色素上皮;遺伝子

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K09444/
• Retinal vascular regeneration for diabetic macular edema by succinate & erythropoietin

  Grant-in-Aid for Scientific Research (C)

  Basic Section 56060:Ophthalmology-related

  Kagawa University

  Kiyoshi Suzuma

  From 01 Apr. 2018, To 31 Mar. 2021, Project Closed

  糖尿病網膜症;エリスロポエチン;コハク酸

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K09404/
• Exploratory study of new lesions on fundus imaging and their molecular mechanisms in diabetic retinopathy

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Tomoaki Murakami

  From 01 Apr. 2017, To 31 Mar. 2020, Project Closed

  糖尿病網膜症;糖尿病黄斑浮腫;光干渉断層計アンギオグラフィー;抗VEGF療法;自己抗体;視細胞障害;抗fumarase抗体;抗hexokinase 1抗体;眼底自発蛍光;眼底イメージング;神経変性;OCT angiography;トランスレーショナルリサーチ;免疫学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K11423/
• High-resolution Imaging using next generation adaprive optics imaging in dry age-related macular degeneration

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  SOTARO OOTO

  From 01 Apr. 2016, To 31 Mar. 2019, Project Closed

  補償光学;加齢黄斑変性;脈絡膜;視細胞;光干渉断層計;走査型レーザー検眼鏡;眼科学;網膜;眼底イメージング

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K11321/
• Pathogenesis of early age-related macular degeneration using adaptive optics SLO

  Grant-in-Aid for Research Activity Start-up

  Kyoto University

  OOTO SOTARO

  From 29 Aug. 2014, To 31 Mar. 2016, Project Closed

  加齢黄斑変性;補償光学;視細胞;走査型レーザー検眼鏡;光干渉断層計;ドルーゼン

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26893131/
• Building an prediction model for the fellow eye involvement of age-relate macular degeneration using genome information, and physiological or morphological feature of photo receptor

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  HIROSHI TAMURA

  From 01 Apr. 2012, To 31 Mar. 2015, Project Closed

  加齢黄斑変性;予測モデル;2眼目;ゲノム;国際情報交換;国際情報交換（アメリカ）

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24592626/
• Evaluation of the pathologic changes of the foveal photoreceptor cells affected with macular edema associated with retinal vein occlusion

  Grant-in-Aid for Scientific Research (C)

  Kagawa University;Kyoto University

  AKITAKA TSUJIKAWA

  From 01 Apr. 2012, To 31 Mar. 2015, Project Closed

  補償光学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24592625/
• Analysis of pathology and development of treatment for dry age-related macular degeneration using adaptive optics scanning laser ophthalmoscopy

  Grant-in-Aid for Young Scientists (B)

  Kyoto University

  Sotaro OOTO

  From 01 Apr. 2011, To 31 Mar. 2013, Project Closed

  加齢黄斑変性;眼底イメージング;視細胞;補償光学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23791979/
• Analysis of retinal nerve fiber bundle damages in glaucoma by using adaptive optics laser scanning ophthalmoscope

  Grant-in-Aid for Scientific Research (C)

  Saitama Medical University;Kyoto University

  Masanori HANGAI

  From 01 Apr. 2011, To 31 Mar. 2014, Project Closed

  緑内障;補償光学;イメージング;網膜神経線維束;神経節細胞;補償光学レーザー走査検眼鏡;網膜神経線維

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592565/
• Pathology of retinitis pigmentosa detected by adaptive optics scanning laser ophthalmoscopy

  Grant-in-Aid for Young Scientists (B)

  Kyoto University

  Sotaro OOTO

  From 01 Apr. 2009, To 31 Mar. 2011, Project Closed

  臨床研究;網膜色素変性;補償光学;走査型レーザー検眼鏡;眼底イメージング;視細胞;網膜再生;光干渉断層計

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21791679/
• Hemodynamic analysis of parafoveal capillaries in eyes with diabetes mellitus using adaptive optics scanning laser ophthalmoscopy

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Akitaka TSUJIKAWA

  From 01 Apr. 2009, To 31 Mar. 2012, Project Closed

  補償光学;走査型レーザー検眼鏡;光干渉断層計;視細胞;血流;糖尿病

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21592256/
• 補償光学適用光干渉断層計による加齢黄斑変性・パキコロイドの病態解明

  Grant-in-Aid for Scientific Research (C)

  Basic Section 56060:Ophthalmology-related

  Kyoto University

  大音 壮太郎

  From 01 Apr. 2022, To 31 Mar. 2025, Declined

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K09790/
• 補償光学適用光干渉断層計を用いた加齢黄斑変性とパキコロイド関連疾患の病態解明

  Grant-in-Aid for Scientific Research (C)

  Basic Section 56060:Ophthalmology-related

  Kyoto University

  大音 壮太郎

  From 01 Apr. 2024, To 31 Mar. 2027, Granted

  加齢黄斑変性;パキコロイド;補償光学;光干渉断層計

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K12760/

External funds: others

• Photoreceptor abnormalities associated with the development and progression of age-related macular degeneration

  京都大学教育研究振興財団　在外研究長期助成

  From 2013, To 2014

  大音壮太郎
• 補償光学適用走査レーザー検眼鏡による早期加齢黄斑変性の病態メカニズム解明

  京都大学若手研究者スタートアップ研究費

  From 2014, To 2014

  大音壮太郎
• 補償光学適用走査レーザー検眼鏡による早期加齢黄斑変性の病態メカニズム解明

  鈴木謙三記念医科学応用研究財団　調査研究補助金

  From 2014, To 2015

  大音壮太郎

Education

Teaching subject(s)

• From Apr. 2014, To Mar. 2015

  Clinical Overview of Surgery III

  Spring, 医学部（人間健康科学科）
• From Apr. 2015, To Mar. 2016

  Clinical Overview of Surgery III

  Spring, 医学部（人間健康科学科）
• From Apr. 2016, To Mar. 2017

  Clinical Overview of Surgery III

  Spring, 医学部（人間健康科学科）
• From Apr. 2017, To Mar. 2018

  Clinical Overview of Surgery III

  Spring, 医学部（人間健康科学科）