Basic Information

Faculty

• Faculty of Medicine

Email Address

• Email Address

  ohara.hiroaki.3jkyoto-u.ac.jp

Academic Degree

• 23 Jan. 2024

  京都大学博士（医学）

Academic Resume (Graduate Schools)

• 京都大学, 大学院医学研究科博士課程医学専攻, 修了
• 京都大学, 大学院医学研究科博士課程医学専攻, 研究指導認定退学

Academic Resume (Undergraduate School/Majors)

• 奈良県立医科大学, 医学部医学科, 卒業
• 奈良県立医科大学, 医学部医学科, 卒業

ID,URL

• J-Global ID

  202201011099158924

• Researcher number

  20964018

researchmap URL

• https://researchmap.jp/hiroakiohara

Research

Papers

• Substitutions of nucleotides at the 3' ends of COL6A1/2/3 exons induce exon skipping associated with collagen VI-related muscular dystrophies and therapeutic strategies

  Seung-Ah Lee; Megumu Ogawa; Yoshihiko Saito; Rui Shimazaki; Tomonari Awaya; Motoyasu Hosokawa; Ryo Kurosawa; Hiroaki Ohara; Akihide Takeuchi; Shinichiro Hayashi; Yu-ichi Goto; Masatoshi Hagiwara; Ichizo Nishino; Satoru Noguchi

  Genetics in Medicine, Apr. 2025

  
• Profiling of pathogenic variants in Japanese patients with sarcoglycanopathy

  Rui Shimazaki; Yoshihiko Saito; Tomonari Awaya; Narihiro Minami; Ryo Kurosawa; Motoyasu Hosokawa; Hiroaki Ohara; Shinichiro Hayashi; Akihide Takeuchi; Masatoshi Hagiwara; Yukiko K. Hayashi; Satoru Noguchi; Ichizo Nishino

  Orphanet Journal of Rare Diseases, 04 Jan. 2025

  
• Branchpoints as potential targets of exon-skipping therapies for genetic disorders.

  Hiroaki Ohara; Motoyasu Hosokawa; Tomonari Awaya; Atsuko Hagiwara; Ryo Kurosawa; Yukiya Sako; Megumu Ogawa; Masashi Ogasawara; Satoru Noguchi; Yuichi Goto; Ryosuke Takahashi; Ichizo Nishino; Masatoshi Hagiwara

  Molecular therapy. Nucleic acids, 12 Sep. 2023

  Access this paper :

  
• Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation

  Eisho Kanemitsu; Xiangdong Zhao; Keiko Iwaisako; Asuka Inoue; Akihide Takeuchi; Shintaro Yagi; Hidetoshi Masumoto; Hiroaki Ohara; Motoyasu Hosokawa; Tomonari Awaya; Junken Aoki; Etsuro Hatano; Shinji Uemoto; Masatoshi Hagiwara

  Translational Research, Nov. 2022

  
• Intracardiac Thrombus Following Rivaroxaban Treatment in a Patient with Atrial Fibrillation Associated with Rheumatic Heart Disease

  Hiroaki Ohara; Shiro Yamamoto; Keiko Nagano; Kazuo Hashikawa

  Journal of Stroke and Cerebrovascular Diseases, Nov. 2019

  

Books and Other Publications

• 指定難病ペディア

  水澤, 英洋; 五十嵐, 隆; 北川, 泰久; 高橋, 和久(内科学); 弓倉, 整, Contributor, 13 ハンチントン病 ［指定難病8］

  日本医師会,診断と治療社 (発売), Jul. 2019

  Find Kyoto University's collection of books :

  

Awards

• 12 Dec. 2021

  第7回日本筋学会学術集会 Student Award 最優秀賞
• 19 May 2021

  第62回日本神経学会学術大会 優秀演題賞
• 12 Dec. 2021

  第7回日本筋学会学術集会 Student Award 最優秀賞
• 19 May 2021

  第62回日本神経学会学術大会 優秀演題賞

External funds: Kakenhi

• ブランチポイントを標的とした新たなエクソンスキップ法の確立

  Grant-in-Aid for Research Activity Start-up

  0801:Pharmaceutical sciences and related fields

  Japanese Red Cross Wakayama Medical Center;Kyoto University

  大原 寛明

  From 31 Aug. 2022, To 31 Mar. 2025, Granted

  スプライシング;ブランチポイント;アンチセンス核酸

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K20710/
• ブランチポイントを標的としたアンチセンス核酸による新規遺伝子治療の確立

  Grant-in-Aid for Early-Career Scientists

  Basic Section 48030:Pharmacology-related

  Kyoto University

  大原 寛明

  From 01 Apr. 2025, To 31 Mar. 2028, Adopted

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25K18711/