Basic Information

Faculty

• Faculty of Pharmaceutical Sciences

Professional Memberships

• From Apr. 2024, To Present

  日本薬学会

Academic Degree

• 修士（薬学）(京都薬科大学)
• 博士（生命科学）(京都大学)

ID,URL

• J-Global ID

  202101004215234133

• Researcher number

  60948686

Research

Papers

• Hexanoic acid improves metabolic health in mice fed high-fat diet

  Takako Ikeda; Yuki Nishimoto; Daisuke Ichikawa; Tomoka Matsunaga; Ami Kawauchi; Ikuo Kimura

  27 Feb. 2025, Lead author, Corresponding author

  
• The pivotal role of a novel free fatty acid receptor GPR164 in the intestinal barrier function

  Takako Ikeda; Yuki Masujima; Keita Watanabe; Akari Nishida; Mayu Yamano; Miki Igarashi; Nobuo Sasaki; Hironori Katoh; Ikuo Kimura

  26 Feb. 2025, Lead author, Corresponding author

  
• Sucrose-preferring gut microbes prevent host obesity by producing exopolysaccharides.

  Hidenori Shimizu; Junki Miyamoto; Keiko Hisa; Ryuji Ohue-Kitano; Hiromi Takada; Mayu Yamano; Akari Nishida; Daiki Sasahara; Yuki Masujima; Keita Watanabe; Shota Nishikawa; Sakura Takahashi; Takako Ikeda; Yuya Nakajima; Naofumi Yoshida; Chiaki Matsuzaki; Takuya Kageyama; Ibuki Hayashi; Akari Matsuki; Ryo Akashi; Seiichi Kitahama; Masako Ueyama; Takumi Murakami; Shinsuke Inuki; Junichiro Irie; Noriko Satoh-Asahara; Hirokazu Toju; Hiroshi Mori; Shinji Nakaoka; Tomoya Yamashita; Atsushi Toyoda; Kenji Yamamoto; Hiroaki Ohno; Takane Katayama; Hiroshi Itoh; Ikuo Kimura

  Nature communications, 29 Jan. 2025

  
• Medium‐chain fatty acid receptor GPR84 deficiency leads to metabolic homeostasis dysfunction in mice fed high‐fat diet

  Akari Nishida; Ryuji Ohue‐Kitano; Yuki Masujima; Hazuki Nonaka; Miki Igarashi; Takako Ikeda; Ikuo Kimura

  FASEB BioAdvances, 17 Oct. 2024

  
• Medium-chain fatty acids suppress lipotoxicity-induced hepatic fibrosis via the immunomodulating receptor GPR84.

  Ryuji Ohue-Kitano; Hazuki Nonaka; Akari Nishida; Yuki Masujima; Daisuke Takahashi; Takako Ikeda; Akiharu Uwamizu; Miyako Tanaka; Motoyuki Kohjima; Miki Igarashi; Hironori Katoh; Tomohiro Tanaka; Asuka Inoue; Takayoshi Suganami; Koji Hase; Yoshihiro Ogawa; Junken Aoki; Ikuo Kimura

  JCI insight, 24 Jan. 2023, Peer-reviewed

  Access this paper :

  
• Acceleration of matrix metalloproteinase-1 production and activation of platelet-derived growth factor receptor beta in human coronary smooth muscle cells by oxidized LDL and 4-hydroxynonenal.

  Satoshi Akiba; Satomi Kumazawa; Hidenori Yamaguchi; Naoya Hontani; Takeyoshi Matsumoto; Takako Ikeda; Mayuko Oka; Takashi Sato

  Biochimica et biophysica acta, Aug. 2006, Peer-reviewed

  
• Short-chain fatty acid receptors and gut microbiota as therapeutic targets in metabolic, immune, and neurological diseases

  Takako Ikeda; Akari Nishida; Mayu Yamano; Ikuo Kimura

  Pharmacology & Therapeutics, Nov. 2022, Peer-reviewed, Lead author

  
• Identification of chemical compounds as an inhibitor of mitochondrial ATP synthesis, leading to an increased stress resistance and an extended lifespan in C. elegans

  Takako Ikeda; Jun-ichi Kishikawa; Yuki Hayashida; Makoto Fujikawa; Ken Yokoyama

  Biochimica et Biophysica Acta (BBA) - Bioenergetics, Nov. 2020, Peer-reviewed, Lead author, Corresponding author

  
• The MYST family histone acetyltransferase complex regulates stress resistance and longevity through transcriptional control of DAF ‐16/ FOXO transcription factors

  Takako Ikeda; Masaharu Uno; Sakiko Honjoh; Eisuke Nishida

  EMBO reports, Oct. 2017, Peer-reviewed, Lead author

  
• The microRNA machinery regulates fasting-induced changes in gene expression and longevity in Caenorhabditis elegans

  Akiko Kogure; Masaharu Uno; Takako Ikeda; Eisuke Nishida

  Journal of Biological Chemistry, Jul. 2017, Peer-reviewed

  
• Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction

  Akira Kobayashi; Takako Tsukide; Tomohiro Miyasaka; Tomoko Morita; Tatsuya Mizoroki; Yoshiro Saito; Yasuo Ihara; Akihiko Takashima; Noriko Noguchi; Akiyoshi Fukamizu; Yosuke Hirotsu; Makiko Ohtsuji; Fumiki Katsuoka; Masayuki Yamamoto

  Genes to Cells, Jun. 2011, Peer-reviewed

  
• Hypoxia stimulates the autocrine regulation of migration of vascular smooth muscle cells via HIF-1α-dependent expression of thrombospondin-1

  Mayuko Osada-Oka; Takako Ikeda; Satoshi Akiba; Takashi Sato

  Journal of Cellular Biochemistry, 01 Aug. 2008, Peer-reviewed

  
• The Role of Thrombospondin-1 in Hypoxia-induced Migration of Human Vascular Smooth Muscle Cells

  Minoru TAKAHASHI; Mayuko OKA; Takako IKEDA; Satoshi AKIBA; Takashi SATO

  YAKUGAKU ZASSHI, 01 Mar. 2008

  
• VEGF-Enhanced Proliferation under Hypoxia by an Autocrine Mechanism in Human Vascular Smooth Muscle Cells

  Mayuko Osada-Oka; Takako Ikeda; Susumu Imaoka; Satoshi Akiba; Takashi Sato

  Journal of Atherosclerosis and Thrombosis, 2008, Peer-reviewed

  

Presentations

• 脂肪酸受容体による生体恒常性の維持機構

  池田貴子

  日本生理学会, 29 Mar. 2024, Invited

  
• 新規脂肪酸受容体GPR164による腸管恒常性維持機構

  池田貴子

  日本免疫食品学会, 15 Nov. 2023, Invited

  

Books and Other Publications

• 食と腸内細菌による宿主の代謝制御.

  高田紘翠; 池田貴子; 木村郁夫

  診断と治療社, Feb. 2025

  
• 代謝疾患と腸内細菌

  池田貴子; 高田紘翠; 木村郁夫

  医歯薬出版株式会社, Nov. 2024

  
• マイクロバイオームによる代謝・内分泌制御

  山野真由; 池田貴子; 西田朱里; 木村郁夫, Joint work

  羊土社, Oct. 2024

  
• 腸内細菌の代謝産物のはたらき

  池田貴子; 西田朱里; 木村郁夫, Joint work, 全て

  南山堂, 05 May 2024

  Find Kyoto University's collection of books :

  
• 短鎖脂肪酸受容体を介したエネルギー代謝と生理作用

  池田貴子; 西田朱里; 山野真由; 木村郁夫

  臨床化学, Aug. 2023

  
• 代謝制御におけるケトン体受容体の役割

  西田 朱里; 泉 綾乃; 池田 貴子; 木村 郁夫

  Oct. 2022

  
• 栄養環境の変化を認識する短鎖脂肪酸受容体

  池田 貴子; 西田 朱里; 山野 真由; 木村 郁夫

  羊土社, May 2022

  Find Kyoto University's collection of books :

  

External funds: Kakenhi

• 新規の脂肪酸受容体GPR164による腸管を起点とした生体機能制御機構

  Grant-in-Aid for Research Activity Start-up

  0909:Sports sciences, physical education, health sciences, and related fields

  Kyoto University

  池田 貴子

  From 31 Aug. 2022, To 31 Mar. 2024, Granted

  脂肪酸受容体;腸管機能制御;中鎖脂肪酸

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K21208/
• 腸管を起点とした全身の生体機能維持に関わる新規脂肪酸受容体の機能解明

  Grant-in-Aid for Early-Career Scientists

  Basic Section 59040:Nutrition science and health science-related

  Kyoto University

  池田 貴子

  From 01 Apr. 2023, To 31 Mar. 2025, Granted

  脂肪酸受容体;腸管を起点とした生体恒常性の維持

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K16794/

Education

Teaching subject(s)

• From 01 Apr. 2024, To 31 Mar. 2025

  Research Proposal Writing Practice A

  8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory Coaching Practice A

  8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Research Proposal Writing Practice B

  8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory IV : Biochemistry and Microbiology

  C906, Fall, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Medicinal Frontier Science Research C

  8408, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Medicinal Frontier Science Research B

  8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Medicinal Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar on Critical Reading of Scientific Papers B

  8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory Coaching Practice A

  8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Research Proposal Writing Practice A

  8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Research Proposal Writing Practice B

  8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Medicinal Frontier Science Research B

  8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Medicinal Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar on Critical Reading of Scientific Papers B

  8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Medical Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Research Proposal Writing Practice A

  8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory Coaching Practice A

  8301, Year-long, Graduate School of Pharmaceutical Sciences, 1