Basic Information

Email Address

• Email Address

  arima.hiroshi.3zkyoto-u.ac.jp

Professional Memberships

• Japanese Society for Transplantation and Cellular Therapy
• Japanese Society for Lymphoreticular Tissue Research
• Japanese Cancer Association
• Japanese Society of Internal Medicine
• Japanese Society of Hematology

Academic Degree

• 23 Jan. 2019

  京都大学博士（医学）

Academic Resume (Undergraduate School/Majors)

• 京都大学, 医学部医学科, 卒業

Research History

• From Jun. 2022, To Present

  Kyoto University, Hospital, Department of Hematology, Assistant Professor
• From Apr. 2019, To May 2022

  IFOM - The FIRC Institute of Molecular Oncology, Genetics of B Cells and Lymphomas Lab (Stefano Casola's Lab), Post Doc
• From Apr. 2017, To Mar. 2019

  Kyoto University, Hospital, Department of Hematology, Clinical Fellow
• From Apr. 2016, To Mar. 2017

  Kyoto University, Graduate School of Medicine, Associate Fellow
• From Apr. 2014, To Mar. 2016

  Kyoto University, Graduate School of Medicine, JSPS (Japan Society for the Promotion of Science) Research Fellowship for Young Scientists
• From Apr. 2009, To Mar. 2012

  Kobe City Medical Center General Hospital, Department of Hematology, Senior Resident
• From Apr. 2007, To Mar. 2009

  Kyoto University, Hospital, Junior Resident

ID,URL

• ORCID ID

  0000-0003-0609-846X

• J-Global ID

  202201019435305141

• Researcher number

  50618014

researchmap URL

• https://researchmap.jp/hiarima

Research

Research Interests

• Tumor immunology
• Malignant lymphoma

Research Areas

• Life sciences, Hematology and oncology, Malignant lymphoma, Tumor immunology

Papers

• Concurrent development of small lymphocytic lymphoma and lung cancer: A report of two cases and a review of the literature.

  Kensuke Nakao; Momoko Nishikori; Masakazu Fujimoto; Hiroshi Arima; Hironori Haga; Akifumi Takaori-Kondo

  Journal of clinical and experimental hematopathology : JCEH, 28 Jun. 2023

  
• [Fatal hepatic failure due to AL amyloidosis in a patient with multiple myeloma].

  Sumie Tabata; Masayuki Kurata; June Takeda; Yuuki Funayama; Nobuhiko Yamauchi; Kazunari Aoki; Aiko Kato; Yuichirou Ono; Hiroshi Arima; Yoko Takiuchi; Seiji Nagano; Akiko Matsushita; Yukihiro Imai; Takayuki Ishikawa; Takayuki Takahashi

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 01 Nov. 2012, Peer-reviewed

  
• Successful living donor liver transplantation for severe hepatic GVHD histologically resembling autoimmune hepatitis after bone marrow transplantation from the same sibling donor.

  Minako Mori; Sumie Tabata; Hisako Hashimoto; Daichi Inoue; Takaharu Kimura; Sonoko Shimoji; Yuya Nagai; Katsuhiro Togami; Kiminari Itoh; Akiko Matsushita; Kenichi Nagai; Eiji Ikeda; Naoya Kimoto; Kenji Uryuhara; Satoru Kaihara; Yukihiro Imai; Masafumi Itoh; Takayuki Takahashi

  Transplant international : official journal of the European Society for Organ Transplantation, 01 May 2010, Peer-reviewed

  
• The EZH2 inhibitor tazemetostat upregulates the expression of CCL17/TARC in B-cell lymphoma and enhances T-cell recruitment.

  Hepei Yuan; Momoko Nishikori; Yasuyuki Otsuka; Hiroshi Arima; Toshio Kitawaki; Akifumi Takaori-Kondo

  Cancer science, Nov. 2021

  Access this paper :

  
• Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development.

  Fumiya Moribe; Momoko Nishikori; Tsuyoshi Takashima; Daiki Taniyama; Nobuyuki Onishi; Hiroshi Arima; Hiroyuki Sasanuma; Remi Akagawa; Fathi Elloumi; Shunichi Takeda; Yves Pommier; Eiichi Morii; Akifumi Takaori-Kondo; Junko Murai

  PloS one, 2021

  
• LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells.

  Tomoyasu Jo; Momoko Nishikori; Yasunori Kogure; Hiroshi Arima; Katsuhiro Sasaki; Yoshiteru Sasaki; Tomoko Nakagawa; Fumie Iwai; Shuji Momose; Aki Shiraishi; Hiroshi Kiyonari; Noritaka Kagaya; Tetsuo Onuki; Kazuo Shin-Ya; Minoru Yoshida; Keisuke Kataoka; Seishi Ogawa; Kazuhiro Iwai; Akifumi Takaori-Kondo

  Blood, 06 Aug. 2020

  
• EZH2 inhibitors restore epigenetically silenced CD58 expression in B-cell lymphomas.

  Yasuyuki Otsuka; Momoko Nishikori; Hiroshi Arima; Kiyotaka Izumi; Toshio Kitawaki; Masakatsu Hishizawa; Akifumi Takaori-Kondo

  Molecular immunology, Mar. 2020

  
• B cells with aberrant activation of Notch1 signaling promote Treg and Th2 cell-dominant T-cell responses via IL-33.

  Hiroshi Arima; Momoko Nishikori; Yasuyuki Otsuka; Wataru Kishimoto; Kiyotaka Izumi; Koubun Yasuda; Tomohiro Yoshimoto; Akifumi Takaori-Kondo

  Blood advances, 25 Sep. 2018

  
• Prognostic impact of activation-induced cytidine deaminase expression for patients with diffuse large B-cell lymphoma.

  Hiroshi Arima; Masakazu Fujimoto; Momoko Nishikori; Toshiyuki Kitano; Wataru Kishimoto; Masakatsu Hishizawa; Tadakazu Kondo; Kouhei Yamashita; Masahiro Hirata; Hironori Haga; Akifumi Takaori-Kondo

  Leukemia & lymphoma, Sep. 2018

  
• Expression of Tim-1 in primary CNS lymphoma.

  Wataru Kishimoto; Momoko Nishikori; Hiroshi Arima; Hiroaki Miyoshi; Yuya Sasaki; Toshio Kitawaki; Kotaro Shirakawa; Takeharu Kato; Yoshitaka Imaizumi; Takayuki Ishikawa; Hitoshi Ohno; Hironori Haga; Koichi Ohshima; Akifumi Takaori-Kondo

  Cancer medicine, Nov. 2016

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• Prognostic significance of pleural or pericardial effusion and the implication of optimal treatment in primary mediastinal large B-cell lymphoma: a multicenter retrospective study in Japan.

  Tomohiro Aoki; Koji Izutsu; Ritsuro Suzuki; Chiaki Nakaseko; Hiroshi Arima; Kazuyuki Shimada; Akihiro Tomita; Makoto Sasaki; Jun Takizawa; Kinuko Mitani; Tadahiko Igarashi; Yoshinobu Maeda; Noriko Fukuhara; Fumihiro Ishida; Nozomi Niitsu; Ken Ohmachi; Hirotaka Takasaki; Naoya Nakamura; Tomohiro Kinoshita; Shigeo Nakamura; Michinori Ogura

  Haematologica, Dec. 2014

  
• Successful allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning for B-cell prolymphocytic leukemia in partial remission.

  Hiroshi Arima; Yuichiro Ono; Sumie Tabata; Akiko Matsushita; Hisako Hashimoto; Takayuki Ishikawa; Takayuki Takahashi

  International journal of hematology, Apr. 2014

  
• IP-10/CXCL10 and MIG/CXCL9 as novel markers for the diagnosis of lymphoma-associated hemophagocytic syndrome.

  Hayato Maruoka; Daichi Inoue; Yoko Takiuchi; Seiji Nagano; Hiroshi Arima; Sumie Tabata; Akiko Matsushita; Takayuki Ishikawa; Tatsuo Oita; Takayuki Takahashi

  Annals of hematology, Mar. 2014

  
• Gender identification by calls and body size of the Streaked Shearwater examined by CHD genes

  Arima Hiroshi; Oka Nariko; Baba Yoshiyuki; Sugawa Hisashi; Ota Takahiro

  ORNITHOLOGICAL SCIENCE, 2014

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• Pleurisy as a novel clinical manifestation associated with human herpesvirus 6 after unrelated cord blood transplantation

  Arima Hiroshi; Kondo Tadakazu; Takahashi Nozomi; Kitano Toshiyuki; Kadowaki Norimitsu; Takaori-Kondo Akifumi

  Journal of Hematopoietic Cell Transplantation, 2014

  
• Simultaneous thrombosis of the mesenteric artery and vein as a novel clinical manifestation of intravascular large B-cell lymphoma.

  Hiroshi Arima; Daichi Inoue; Sumie Tabata; Akiko Matsushita; Yukihiro Imai; Takayuki Ishikawa; Takayuki Takahashi

  Acta haematologica, 2014

  
• Impact of occult bone marrow involvement on the outcome of rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone therapy for diffuse large B-cell lymphoma.

  Hiroshi Arima; Hayato Maruoka; Koji Nasu; Sumie Tabata; Masayuki Kurata; Akiko Matsushita; Yukihiro Imai; Takayuki Takahashi; Takayuki Ishikawa

  Leukemia & lymphoma, Dec. 2013

  
• Therapeutic effects of lenalidomide on hemorrhagic intestinal myeloma-associated AL amyloidosis.

  Seiji Nagano; Minako Mori; Aiko Kato; Yuichiro Ono; Kazunari Aoki; Hiroshi Arima; Yoko Takiuchi; Sumie Tabata; Soshi Yanagita; Akiko Matsushita; Takayuki Ishikawa; Hiroyuki Imai; Takayuki Takahashi

  Internal medicine (Tokyo, Japan), 2013

  
• Monocytic crisis of chronic myeloid leukemia in the era of tyrosine kinase inhibitor.

  Hiroko Tsunemine; Hiroshi Arima; Kiminari Itoh; Emiko Sakane-Ishikawa; Hiroshi Akasaka; Taiichi Kodaka; Takayuki Takahashi

  Journal of clinical and experimental hematopathology : JCEH, 2013

  
• Central nervous system involvement of primary cutaneous diffuse large B cell lymphoma-leg type diagnosed according to the WHO 2008 classification.

  Kazunari Aoki; Hiroshi Arima; Sumie Tabata; Akiko Matsushita; Takayuki Ishikawa; Takayuki Takahashi

  Annals of hematology, Dec. 2012

  
• Human herpes virus 6-associated myelitis following allogeneic bone marrow transplantation.

  Kazunari Aoki; Hiroshi Arima; Aiko Kato; Hisako Hashimoto; Sumie Tabata; Akiko Matsushita; Takayuki Ishikawa

  Annals of hematology, Oct. 2012

  
• Successful treatment of γ-heavy-chain disease with rituximab and fludarabine.

  Daichi Inoue; Akiko Matsushita; Mineyo Kiuchi; Yoko Takiuchi; Seiji Nagano; Hiroshi Arima; Minako Mori; Sumie Tabata; Akiko Yamashiro; Hayato Maruoka; Tatsuo Oita; Yukihiro Imai; Takayuki Takahashi

  Acta haematologica, 2012

  
• Leukemic manifestation of blastic plasmacytoid dendritic cell neoplasm lacking skin lesion : a borderline case between acute monocytic leukemia.

  Yoko Takiuchi; Hayato Maruoka; Kazunari Aoki; Aiko Kato; Yuichiro Ono; Seiji Nagano; Hiroshi Arima; Daichi Inoue; Minako Mori; Sumie Tabata; Soshi Yanagita; Akiko Matsushita; Mari Nishio; Yukihiro Imai; Yukihiro Imai; Kiminari Ito; Haruyuki Fujita; Norimitsu Kadowaki; Takayuki Ishikawa; Takayuki Takahashi

  Journal of clinical and experimental hematopathology : JCEH, 2012

  
• Enteropathy-associated T-cell lymphoma type II complicated by autoimmune hemolytic anemia.

  Aiko Kato; Yoko Takiuchi; Kazunari Aoki; Yuichiro Ono; Hiroshi Arima; Seiji Nagano; Sumie Tabata; Soshi Yanagita; Akiko Matsushita; Hayato Maruoka; Masaya Wada; Yukihiro Imai; Takayuki Ishikawa; Takayuki Takahashi

  Journal of clinical and experimental hematopathology : JCEH, 2011

  
• Systemic follicular lymphoma with massive intestinal involvement with leukemic manifestation.

  Yuichiro Ono; Kazunari Aoki; Aiko Kato; Hiroshi Arima; Yohko Takiuchi; Seiji Nagano; Sumie Tabata; Sohshi Yanagita; Akiko Matsushita; Hayato Maruoka; Yukihiro Imai; Takayuki Ishikawa; Takayuki Takahashi

  Journal of clinical and experimental hematopathology : JCEH, 2011

  
• Excellent therapeutic effect of tocilizumab on intestinal amyloid a deposition secondary to active rheumatoid arthritis.

  Daichi Inoue; Hiroshi Arima; Chiharu Kawanami; Yoko Takiuchi; Seiji Nagano; Takaharu Kimura; Sonoko Shimoji; Minako Mori; Sumie Tabata; Soshi Yanagita; Akiko Matsushita; Kenichi Nagai; Yukihiro Imai; Takayuki Takahashi

  Clinical rheumatology, Oct. 2010

  
• Histiocytic sarcoma and underlying chronic myelomonocytic leukemia: a proposal for the developmental classification of histiocytic sarcoma.

  Minako Mori; Akiko Matsushita; Yohko Takiuchi; Hiroshi Arima; Seiji Nagano; Sonoko Shimoji; Takaharu Kimura; Daichi Inoue; Sumie Tabata; Sohshi Yanagita; Kenichi Nagai; Yukihiro Imai; Takayuki Takahashi

  International journal of hematology, Jul. 2010

  
• Fulminant sepsis caused by Bacillus cereus in patients with hematologic malignancies: analysis of its prognosis and risk factors.

  Daichi Inoue; Yuya Nagai; Minako Mori; Seiji Nagano; Yoko Takiuchi; Hiroshi Arima; Takaharu Kimura; Sonoko Shimoji; Katsuhiro Togami; Sumie Tabata; Soshi Yanagita; Akiko Matsushita; Kenichi Nagai; Yukihiro Imai; Hiroshi Takegawa; Takayuki Takahashi

  Leukemia & lymphoma, May 2010

  
• [Therapeutic efficacy of cyclosporin A for refractory angioimmunoblastic T cell lymphoma].

  Minako Mori; Daichi Inoue; Hiroshi Arima; Yohko Takiuchi; Seiji Nagano; Takaharu Kimura; Sonoko Shimoji; Yuya Nagai; Sumie Tabata; Sohshi Yanagita; Akiko Matsushita; Kenichi Nagai; Yukihiro Imai; Takayuki Takahashi

  [Rinsho ketsueki] The Japanese journal of clinical hematology, May 2010

  
• Successful treatment of extranodal natural killer/T-cell lymphoma, nasal type, complicated by severe hemophagocytic syndrome, with dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide chemotherapy followed by autologous stem cell transplant.

  Daichi Inoue; Yuya Nagai; Yoko Takiuchi; Seiji Nagano; Hiroshi Arima; Takaharu Kimura; Sonoko Shimoji; Minako Mori; Katsuhiro Togami; Sumie Tabata; Soshi Yanagita; Akiko Matsushita; Kenichi Nagai; Hayato Maruoka; Yukihiro Imai; Ritsuro Suzuki; Takayuki Takahashi

  Leukemia & lymphoma, Apr. 2010

  
• Successful allogeneic bone marrow transplantation for diamond-blackfan anemia complicated by severe cardiac dysfunction due to transfusion-induced hemochromatosis.

  Sumie Tabata; Minako Mori; Yuya Nagai; Hisako Hashimoto; Hiroshi Arima; Seiji Nagano; Yoko Takiuchi; Daichi Inoue; Takaharu Kimura; Sonoko Shimoji; Soshi Yanagita; Kiminari Ito; Akiko Matsushita; Kenichi Nagai; Takayuki Takahashi

  Internal medicine (Tokyo, Japan), 2010

  
• [Successful treatment of chronic disseminated intravascular coagulation syndrome with continuous subcutaneous infusion of heparin using a mobile infusion pump: report of 2 cases].

  Katsuhiro Togami; Yuya Nagai; Hiroshi Arima; Sonoko Shimoji; Takahiro Kimura; Daichi Inoue; Minako Mori; Haruyuki Fujita; Sumie Tabata; Masayuki Kurata; Soshi Yanagida; Akiko Matsushita; Kenichi Nagai; Shuichiroh Kaji; Takayuki Takahashi

  [Rinsho ketsueki] The Japanese journal of clinical hematology, Dec. 2009

  
• Usefulness of avian buccal cells for molecular sexing

  Arima Hiroshi; Ohnishi Naoki

  ORNITHOLOGICAL SCIENCE, 2006

  
• Correlation between the pitch of calls and external measurements of Streaked Shearwaters Calonectris leucomelas breeding on Kanmuri Island

  Arima Hiroshi; Sugawa Hisashi

  Japanese Journal of Ornithology, 2004

  

Misc.

• 肝アミロイドーシスによる肝不全で死亡した多発性骨髄腫

  田端 淑恵; 倉田 雅之; 竹田 淳恵; 船山 由樹; 山内 寛彦; 青木 一成; 加藤 愛子; 小野 祐一郎; 有馬 浩史; 瀧内 曜子; 永野 誠治; 松下 章子; 今井 幸弘; 石川 隆之; 高橋 隆幸

  臨床血液, Nov. 2012

  
• 高リスクMDSに対するAzacitidineの治療効果

  田端 淑恵; 竹田 淳恵; 船山 由樹; 山内 寛彦; 青木 一成; 加藤 愛子; 小野 祐一郎; 有馬 浩史; 瀧内 曜子; 永野 誠治; 松下 章子; 石川 隆之

  臨床血液, Sep. 2012

  
• 6カラーフローサイトメトリーによる造血器腫瘍のイムノフェノタイピング

  丸岡 隼人; 江藤 正明; 那須 浩二; 老田 達雄; 岸本 健治; 宇佐美 郁哉; 青木 一成; 小野 祐一郎; 加藤 愛子; 有馬 浩史; 瀧内 曜子; 永野 誠治; 田端 淑恵; 柳田 宗之; 松下 章子; 高橋 隆幸; 石川 隆之

  神戸市立病院紀要, Mar. 2012

  
• Double Ph cloneが確認されたCMLに対しダサチニブを使用した1例

  永野 誠治; 竹田 淳恵; 船山 由樹; 山内 寛彦; 青木 一成; 小野 祐一郎; 加藤 愛子; 有馬 浩史; 瀧内 曜子; 田端 淑恵; 松下 章子; 石川 隆之

  臨床血液, Jan. 2012

  
• 大顆粒リンパ球性白血病に合併した赤芽球癆によるヘモクロマトーシスに行った鉄キレート療法

  永野 誠治; 青木 一成; 小野 祐一郎; 加藤 愛子; 有馬 浩史; 瀧内 曜子; 田端 淑恵; 柳田 宗之; 松下 章子; 石川 隆之

  臨床血液, Aug. 2011

  
• Expression of Tim-1 and Its Pathogenetic Role in Primary CNS Lymphoma

  Momoko Nishikori; Wataru Kishimoto; Hiroshi Arima; Kotaro Shirakawa; Toshio Kitawaki; Akifumi Takaori-Kondo

  BLOOD, Dec. 2014

  

Awards

• 31 Oct. 2014

  第76回日本血液学会学術集会優秀ポスター賞
• 03 Dec. 2016

  The 58th ASH Annual Meeting and Exposition ASH Abstract Achievement Award
• 12 Oct. 2018

  EHA-JSH Collaborative Exchange Award

External funds: Kakenhi

• B細胞リンパ腫がB細胞受容体シグナル依存性から脱却するメカニズムとその治療応用

  Grant-in-Aid for Early-Career Scientists

  Basic Section 54010:Hematology and medical oncology-related

  Kyoto University

  有馬 浩史

  From 01 Apr. 2023, To 31 Mar. 2026, Granted

  悪性リンパ腫;ダブルヒットリンパ腫;B細胞受容体

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K15325/