Basic Information

Academic Degree

• 博士（医学）(京都大学)

Language of Instruction

• Japanese
• English

ID,URL

• ORCID ID

  0000-0001-9781-7321

• J-Global ID

  202001019621010904

• Researcher number

  00886319

researchmap URL

• https://researchmap.jp/tmnbs

Research

Research Topics, Overview of the research

• Research Topics

  Nuclear Medicine, Molecular Imaging

Research Interests

• Molecular Imaging
• Nuclear Medicine

Research Areas

• Life sciences, Radiology, Nuclear Medicine

Papers

• Imaging Characteristics and Diagnostic Performance of 2-deoxy-2-[18F]fluoro-D-Glucose PET/CT for Melanoma Patients Who Demonstrate Hyperprogressive Disease When Treated with Immunotherapy.

  Ryusuke Nakamoto; Lisa C Zaba; Jarrett Rosenberg; Sunil Arani Reddy; Tomomi W Nobashi; Valentina Ferri; Guido Davidzon; Carina Mari Aparici; Judy Nguyen; Farshad Moradi; Andrei Iagaru; Benjamin Lewis Franc

  Molecular imaging and biology, Feb. 2021

  
• [18F]F-AraGの臨床利用に向けた多目的合成装置による製造法の検討

  志水 陽一; 野橋 智美; 中本 裕士

  核医学, Aug. 2022

  
• Novel Artificial Intelligence-based Technology for Chest Computed Tomography Analysis of Idiopathic Pulmonary Fibrosis.

  Tomohiro Handa; Kiminobu Tanizawa; Tsuyoshi Oguma; Ryuji Uozumi; Kizuku Watanabe; Naoya Tanabe; Takafumi Niwamoto; Hiroshi Shima; Ryobu Mori; Tomomi W Nobashi; Ryo Sakamoto; Takeshi Kubo; Atsuko Kurosaki; Kazuma Kishi; Yuji Nakamoto; Toyohiro Hirai

  Annals of the American Thoracic Society, Mar. 2022

  
• Whole-body PET Imaging of T-cell Response to Glioblastoma.

  Tomomi W Nobashi; Aaron T Mayer; Zunyu Xiao; Carmel T Chan; Aisling M Chaney; Michelle L James; Sanjiv S Gambhir

  Clinical cancer research : an official journal of the American Association for Cancer Research, 01 Dec. 2021

  
• Imaging alloreactive T cells provides early warning of organ transplant rejection.

  Toshihito Hirai; Aaron T Mayer; Tomomi W Nobashi; Po-Yu Lin; Zunyu Xiao; Tomokatsu Udagawa; Kinya Seo; Federico Simonetta; Jeanette Baker; Alan G Cheng; Robert S Negrin; Sanjiv S Gambhir

  JCI insight, 08 Jul. 2021

  
• CT-ORG, a new dataset for multiple organ segmentation in computed tomography.

  Blaine Rister; Darvin Yi; Kaushik Shivakumar; Tomomi Nobashi; Daniel L Rubin

  Scientific data, 11 Nov. 2020

  
• Visualization of Activated T Cells by OX40-ImmunoPET as a Strategy for Diagnosis of Acute Graft-versus-Host Disease.

  Israt S Alam; Federico Simonetta; Lukas Scheller; Aaron T Mayer; Surya Murty; Ophir Vermesh; Tomomi W Nobashi; Juliane K Lohmeyer; Toshihito Hirai; Jeanette Baker; Kenneth H Lau; Robert Negrin; Sanjiv S Gambhir

  Cancer research, 01 Nov. 2020

  
• Detectability of PET/CT with 68Ga-DOTATOC for identifying suspected or unknown primary neuroendocrine tumors

  Nakamoto Yuji; Sano Kohei; Nakatani Koya; Arimoto Maya; Nobashi Tomomi; Togashi Kaori

  JOURNAL OF NUCLEAR MEDICINE, May 2014, Peer-reviewed

  
• Detectability of PET/CT with 68Ga-DOTATOC for identifying suspected or unknown primary neuroendocrine tumors

  Nakamoto Yuji; Sano Kohei; Nakatani Koya; Arimoto Maya; Nobashi Tomomi; Togashi Kaori

  JOURNAL OF NUCLEAR MEDICINE, May 2014, Peer-reviewed

  
• Evaluation of intratumoral microenvironment with 18F-misonidazole PET and dynamic contrast enhanced CT in tumor-bearing mice models

  Koyasu Sho; Nakamoto Yuji; Harada Hiroshi; Kimura Hiroyuki; Sano Kohei; Koizumi Koji; Tsuji Yoshihisa; Nobashi Tomomi; Kurihara Kensuke; Togashi Kaori

  JOURNAL OF NUCLEAR MEDICINE, May 2014, Peer-reviewed

  
• 粘膜悪性黒色腫におけるFDG PET/CTの検出能と予後予測能

  北口 耕輔; 中本 裕士; 野橋 智美; 子安 翔; 三宅 可奈江; 石守 崇好; 佐賀 恒夫

  核医学, Oct. 2020

  
• ICOS Is an Indicator of T-cell-Mediated Response to Cancer Immunotherapy.

  Zunyu Xiao; Aaron T Mayer; Tomomi W Nobashi; Sanjiv S Gambhir

  Cancer research, 15 Jul. 2020, Peer-reviewed

  
• Prognostic value of volumetric PET parameters at early response evaluation in melanoma patients treated with immunotherapy.

  Ryusuke Nakamoto; Lisa C Zaba; Jarrett Rosenberg; Sunil Arani Reddy; Tomomi Watanabe Nobashi; Guido Davidzon; Carina Mari Aparici; Judy Nguyen; Farshad Moradi; Andrei Iagaru; Benjamin Lewis Franc

  European journal of nuclear medicine and molecular imaging, 15 Apr. 2020, Peer-reviewed

  
• Comparison of 3 Interpretation Criteria for 68Ga-PSMA11 PET Based on Inter- and Intrareader Agreement.

  Akira Toriihara; Tomomi Nobashi; Lucia Baratto; Heying Duan; Farshad Moradi; Sonya Park; Negin Hatami; Carina Mari Aparici; Guido Davidzon; Andrei Iagaru

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Apr. 2020, Peer-reviewed

  
• Performance Comparison of Individual and Ensemble CNN Models for the Classification of Brain 18F-FDG-PET Scans.

  Tomomi Nobashi; Claudia Zacharias; Jason K Ellis; Valentina Ferri; Mary Ellen Koran; Benjamin L Franc; Andrei Iagaru; Guido A Davidzon

  Journal of digital imaging, Apr. 2020, Peer-reviewed

  
• Prognostic value of somatostatin receptor expressing tumor volume calculated from 68Ga-DOTATATE PET/CT in patients with well-differentiated neuroendocrine tumors.

  Akira Toriihara; Lucia Baratto; Tomomi Nobashi; Sonya Park; Negin Hatami; Guido Davidzon; Pamela L Kunz; Andrei Iagaru

  European journal of nuclear medicine and molecular imaging, Oct. 2019, Peer-reviewed

  
• Predicting Response to Immunotherapy by Evaluating Tumors, Lymphoid Cell-Rich Organs, and Immune-Related Adverse Events Using FDG-PET/CT.

  Tomomi Nobashi; Lucia Baratto; Sunil A Reddy; Sandhya Srinivas; Akira Toriihara; Negin Hatami; Thomas K Yohannan; Erik Mittra

  Clinical nuclear medicine, Apr. 2019, Peer-reviewed

  
• PD-1 Blockade-induced Inflammatory Arthritis.

  Tomomi Nobashi; Erik Mittra

  Radiology, Dec. 2018, Peer-reviewed

  
• Enhanced intestinal 2-deoxy-2-[18F]fluoro-D-glucose uptake under metformin is not fully suppressed by loperamide.

  Tomomi Nobashi; Tsuneo Saga; Yuji Nakamoto; Yoichi Shimizu; Sho Koyasu; Takayoshi Ishimori; Masao Watanabe; Hiroyuki Kimura; Kaori Togashi

  Endocrine regulations, 01 Oct. 2018, Peer-reviewed

  
• Effects of diffusion time on non-Gaussian diffusion and intravoxel incoherent motion (IVIM) MRI parameters in breast cancer and hepatocellular carcinoma xenograft models.

  Mami Iima; Tomomi Nobashi; Hirohiko Imai; Sho Koyasu; Tsuneo Saga; Yuji Nakamoto; Masako Kataoka; Akira Yamamoto; Tetsuya Matsuda; Kaori Togashi

  Acta radiologica open, Jan. 2018, Peer-reviewed

  
• 造影ダイナミックCTとフッ素18フルオロミソニダゾール陽電子放出断層撮像法を用いた、腫瘍間質の評価および腫瘍低酸素との関連性の評価

  子安 翔; 辻 喜久; 原田 浩; 中本 裕士; 野橋 智美; 木村 寛之; 佐野 紘平; 小泉 幸司; 濱路 政嗣; 富樫 かおり

  JSMI Report, Dec. 2016

  
• 18F-FDG Uptake in Less Affected Lung Field Provides Prognostic Stratification in Patients with Interstitial Lung Disease.

  Tomomi Nobashi; Takeshi Kubo; Yuji Nakamoto; Tomohiro Handa; Sho Koyasu; Takayoshi Ishimori; Michiaki Mishima; Kaori Togashi

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Dec. 2016, Peer-reviewed

  
• 造影ダイナミックCTとフッ素18フルオロミソニダゾール陽電子放出断層撮像法を用いた、腫瘍間質の評価および腫瘍低酸素との関連性の評価

  子安 翔; 辻 喜久; 原田 浩; 中本 裕士; 野橋 智美; 木村 寛之; 佐野 紘平; 小泉 幸司; 濱路 政嗣; 富樫 かおり

  核医学, Oct. 2016

  
• The utility of PET/CT with (68)Ga-DOTATOC in sarcoidosis: comparison with (67)Ga-scintigraphy.

  Tomomi Nobashi; Yuji Nakamoto; Takeshi Kubo; Takayoshi Ishimori; Tomohiro Handa; Kiminobu Tanizawa; Kohei Sano; Michiaki Mishima; Kaori Togashi

  Annals of nuclear medicine, Oct. 2016, Peer-reviewed

  
• Evaluation of Tumor-associated Stroma and Its Relationship with Tumor Hypoxia Using Dynamic Contrast-enhanced CT and (18)F Misonidazole PET in Murine Tumor Models.

  Sho Koyasu; Yoshihisa Tsuji; Hiroshi Harada; Yuji Nakamoto; Tomomi Nobashi; Hiroyuki Kimura; Kohei Sano; Koji Koizumi; Masatsugu Hamaji; Kaori Togashi

  Radiology, Mar. 2016, Peer-reviewed

  
• Prognostic value of fluorine-18 fludeoxyglucose positron emission tomography parameters differs according to primary tumour location in small-cell lung cancer.

  Tomomi Nobashi; Sho Koyasu; Yuji Nakamoto; Takeshi Kubo; Takayoshi Ishimori; Young H Kim; Akihiko Yoshizawa; Kaori Togashi

  The British journal of radiology, 2016, Peer-reviewed

  
• Total lesion glycolysis as an IgG4-related disease activity marker.

  Yoshinari Nakatsuka; Tomohiro Handa; Yuji Nakamoto; Tomomi Nobashi; Hajime Yoshihuji; Kiminobu Tanizawa; Kohei Ikezoe; Akihiko Sokai; Takeshi Kubo; Toyohiro Hirai; Kazuo Chin; Kaori Togashi; Tsuneyo Mimori; Michiaki Mishima

  Modern rheumatology, Jul. 2015, Peer-reviewed

  
• A rigid and bioabsorbable material for anterior chest wall reconstruction in a canine model.

  Masatsugu Hamaji; Fumitsugu Kojima; Sho Koyasu; Tomomi Nobashi; Tatsuaki Tsuruyama; Hiroshi Date; Tatsuo Nakamura

  Interactive cardiovascular and thoracic surgery, Mar. 2015, Peer-reviewed

  
• 神経内分泌腫瘍に対するDOTATOC-PET/CT診断 後期像に臨床的意義はあるか?

  中本 裕士; 佐野 紘平; 石守 崇好; 早川 延幸; 野橋 智美; 西松 佳代; 中本 隆介; 富樫 かおり

  核医学, Sep. 2014

  

Misc.

• The effect of metformin on gut in F-18-FDG PET/CT: comparison with autoradiograph and expression of GLUT-1 and GLUT-2

  Tomomi Nobashi; Yoichi Shimizu; Sho Koyasu; Tsuneo Saga; Yuji Nakamoto; Takayoshi Ishimori; Kaori Togashi

  JOURNAL OF NUCLEAR MEDICINE, May 2017

  
• シンチグラフィによる肺移植患者における胃排出能の評価:MRIを用いた蠕動評価との関連

  早川延幸; 中本裕士; 陳豊史; 木戸晶; 藤本晃司; 石守崇好; 栗原研輔; 西松佳代; 野橋智美; 中本隆介; 富樫かおり

  核医学, 30 Nov. 2014

  
• Preliminary assessment of the risk of bone marrow involvement by FDG PET/CT _ focusing on anatomical distribution patterns of the accumulation

  K. Nakatani; Y. Nakamoto; N. Hayakawa; K. Nishimatsu; T. Nobashi; K. Togashi

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Oct. 2014

  
• Clinical value of scanning additional areas in FDG-PET/CT for breast cancer patients

  T. Nobashi; Y. Nakamoto; K. Nakatani; Y. Hamanaka; K. Hayashida; K. Togashi

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Oct. 2014

  
• The prognostic value of FDG PET/CT volumetric parameters for small cell lung cancer, according to the primary tumor location: center or periphery

  Tomomi Nobashi; Sho Koyasu; Yuji Nakamoto; Takeshi Kubo; Masahiro Tomoi; Kohei Hayashida; Eiji Tadamura; Kaori Togashi

  JOURNAL OF NUCLEAR MEDICINE, May 2015

  
• Prognostic value of FDG-PET/CT in small cell lung cancer, according to location of primary tumour

  T. Nobashi; S. Koyasu; Y. Nakamoto; T. Kubo; E. Tadamura; K. Hayashida; M. Tomoi; K. Togashi

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Oct. 2014

  
• Evaluation of tumour hypoxia and cancer stroma using F-18-misonidazole PET and dynamic contrast enhanced CT in tumor-bearing mice models

  S. Koyasu; Y. Nakamoto; H. Harada; Y. Tsuji; H. Kimura; K. Sano; T. Nobashi; K. Togashi

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Oct. 2014

  
• FDG uptake observed around the lumbar interspinous process

  Kayo Nishimatsu; Yuji Nakamoto; Koya Nakatani; Kensuke Kurihara; Nobuyuki Hayakawa; Maya Arimoto; Sho Koyasu; Tomomi Nobashi; Kaori Togashi

  JOURNAL OF NUCLEAR MEDICINE, May 2014

  
• Ga-68-DOTATOC-PET/CT for tumor localization in tumor-induced osteomalacia

  Nobuyuki Hayakawa; Yuji Nakamoto; Koya Nakatani; Maya Arimoto; Sho Koyasu; Kayo Nishimatsu; Tomomi Nobashi; Kaori Togashi

  JOURNAL OF NUCLEAR MEDICINE, May 2014

  
• Ga-68-DOTATOC-PET/CT for tumor localization in tumor-induced osteomalacia

  Nobuyuki Hayakawa; Yuji Nakamoto; Koya Nakatani; Maya Arimoto; Sho Koyasu; Kayo Nishimatsu; Tomomi Nobashi; Kaori Togashi

  JOURNAL OF NUCLEAR MEDICINE, May 2014

  
• FDG uptake observed around the lumbar interspinous process

  Kayo Nishimatsu; Yuji Nakamoto; Koya Nakatani; Kensuke Kurihara; Nobuyuki Hayakawa; Maya Arimoto; Sho Koyasu; Tomomi Nobashi; Kaori Togashi

  JOURNAL OF NUCLEAR MEDICINE, May 2014

  
• 粘膜悪性黒色腫におけるFDG PET/CTの検出能と予後予測能

  北口耕輔; 中本裕士; 野橋智美; 子安翔; 三宅可奈江; 石守崇好; 佐賀恒夫

  核医学(Web), 2020

  
• 造影ダイナミックCTとフッ素¹⁸フルオロミソニダゾール陽電子放出断層撮像法を用いた,腫瘍間質の評価および腫瘍低酸素との関連性の評価

  子安翔; 辻喜久; 原田浩; 中本裕士; 野橋智美; 木村寛之; 佐野紘平; 小泉幸司; 濱路政嗣; 富樫かおり

  核医学(Web), 2016

  

Awards

• 11 Jul. 2020

  Center for Molecular Imaging Innovation & Translation at SNMMI, 2nd place at Young Investigator Award

External funds: Kakenhi

• Visualization of T cell exhaustion using ImmunoPET

  Grant-in-Aid for Early-Career Scientists

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  野橋 智美

  From 01 Apr. 2021, To 31 Mar. 2023, Granted

  Tim-3;疲弊化免疫細胞;immunoPET;悪性黒色腫;PET;分子イメージング;免疫療法;T細胞;チェックポイント

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K15764/
• PET分子画像診断を用いた転移性担癌モデルでの癌攻撃免疫細胞の画像診断法の開発

  Grant-in-Aid for Research Activity Start-up

  0901:Oncology and related fields

  Kyoto University

  野橋 智美

  From 11 Sep. 2020, To 31 Mar. 2023, Granted

  悪性黒色腫;免疫療法;immunoPET;分子イメージング;OX40;PET;活性化T細胞;免疫細胞イメージング;T細胞イメージング

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K22844/
• Activated T cell PET imaging for the evaluation of checkpoint inhibitor immunotherapy

  Grant-in-Aid for Early-Career Scientists

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  野橋 智美

  From 01 Apr. 2023, To 31 Mar. 2026, Granted

  免疫PET;免疫療法;T細胞イメージング;治療効果モニタリング;活性化T細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K14865/