Basic Information

Professional Memberships

• The Japan Neuroscience Society
• Japanese Society for Magnetic Resonance in Medicine
• The Japanese Society of Psychiatry and Neurology

Academic Degree

• 博士（医学）(浜松医科大学)

Academic Resume (Graduate Schools)

• 浜松医科大学, 大学院博士課程医学系研究科, 修了

Academic Resume (Undergraduate School/Majors)

• 浜松医科大学, 医学部医学科, 卒業

High School

• High School

  筑波大学附属駒場高校

Research History

• From Sep. 2019, To Present

  京都大学医学部附属病院精神科神経科, 助教
• From 16 Oct. 2017

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• From 01 Jul. 2013

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• From 01 Apr. 2010

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• From 01 Apr. 2010

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• From 01 Apr. 2009

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• From 01 Aug. 2003

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• From 01 May 2003

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• From 01 May 2002

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ID,URL

• J-Global ID

  201701016459488221

researchmap URL

• https://researchmap.jp/7000021621

Research

Research Areas

• Life sciences, Psychiatry, Neuroimaging

Papers

• Autism-spectrum quotient mediates the relationship between clinical symptoms and quality of life in schizophrenia

  Miki Ishizuka; Sadao Otsuka; Jun Miyata; Yujiro Yoshihara; Manabu Kubota; Toshiya Murai

  Schizophrenia Research, Jan. 2025, Peer-reviewed

  
• Nuclei-specific abnormalities of amygdala functional connectivity and their changes after multiple types of treatments for depression: a multicenter MRI study

  Naoya Oishi; Yuzuki Ishikawa; Yusuke Kyuragi; Momoko Hatakoshi; Jinichi Hirano; Takamasa Noda; Yujiro Yoshihara; Hiroyuki Igarashi; Kento Takahashi; Shingo Murakami; Hiroyuki Kanno; Akihiro Takamiya; Junya Matsumoto; Fumitoshi Kodaka; Kazuyuki Nakagome; Masaru Mimura; Toshiya Murai; Taro Suwa

  28 Jan. 2025

  
• Gray and White Matter Microstructural Alterations in Major Depressive Disorder: A Multi-Center Diffusion Imaging Study

  Toshiya Murai; Kento Takahashi; Taro Suwa; Yujiro Yoshihara; Yusuke Kyuragi; Naoya Oishi; Harumasa Takano; Takamasa Noda; Jinichi Hirano; Momoko Hatakoshi; Yuzuki Ishikawa; Jun Miyata; Hiroyuki Igarashi; Hiroyuki Kanno; Shingo Murakami; Masaru Mimura; Kazuyuki Nakagome

  26 Dec. 2024

  
• Electroconvulsive therapy-specific volume changes in nuclei of the amygdala and their relationship to long-term anxiety improvement in depression

  Yuzuki Ishikawa; Naoya Oishi; Yusuke Kyuragi; Momoko Hatakoshi; Jinichi Hirano; Takamasa Noda; Yujiro Yoshihara; Yuri Ito; Jun Miyata; Kiyotaka Nemoto; Yoshihisa Fujita; Hiroyuki Igarashi; Kento Takahashi; Shingo Murakami; Hiroyuki Kanno; Yudai Izumi; Akihiro Takamiya; Junya Matsumoto; Fumitoshi Kodaka; Kazuyuki Nakagome; Masaru Mimura; Toshiya Murai; Taro Suwa

  Molecular Psychiatry, 16 Dec. 2024

  
• Generalizable and transportable resting-state neural signatures characterized by functional networks, neurotransmitters, and clinical symptoms in autism

  Takashi Itahashi; Ayumu Yamashita; Yuji Takahara; Noriaki Yahata; Yuta Y. Aoki; Junya Fujino; Yujiro Yoshihara; Motoaki Nakamura; Ryuta Aoki; Tsukasa Okimura; Haruhisa Ohta; Yuki Sakai; Masahiro Takamura; Naho Ichikawa; Go Okada; Naohiro Okada; Kiyoto Kasai; Saori C. Tanaka; Hiroshi Imamizu; Nobumasa Kato; Yasumasa Okamoto; Hidehiko Takahashi; Mitsuo Kawato; Okito Yamashita; Ryu-ichiro Hashimoto

  Molecular Psychiatry, 28 Sep. 2024

  
• メランコリー型うつ病バイオマーカーを対象とした結合ニューロフィードバック 抑うつ・反芻症状の改善

  茂木 智和; 山田 貴志; 河島 孝彦; 小林 祐子; 吉原 雄二郎; 宮田 淳; 村井 俊哉; 川人 光男; Taylor Jessica

  精神神経学雑誌, Sep. 2021

  
• Generalisable functional imaging classifiers of schizophrenia have multifunctionality as trait, state, and staging biomarkers

  Takahiko Kawashima; Ayumu Yamashita; Yujiro Yoshihara; Yuko Kobayashi; Naohiro Okada; Kiyoto Kasai; Ming-Chyi Huang; Akira Sawa; Junichiro Yoshimoto; Okito Yamashita; Toshiya Murai; Jun Miyata; Mitsuo Kawato; Hidehiko Takahashi

  04 Jan. 2024

  
• Segmentation and volume estimation of habenula using deep-learning in patients with depression

  Yusuke Kyuragi; Naoya Oishi; Momoko Hatakoshi; Jinichi Hirano; Takamasa Noda; Yujiro Yoshihara; Yuri Ito; Hiroyuki Igarashi; Jun Miyata; Kento Takahashi; Kei Kamiya; Junya Matsumoto; Tomohisa Okada; Yasutaka Fushimi; Kazuyuki Nakagome; Masaru Mimura; Toshiya Murai; Taro Suwa

  Biological Psychiatry Global Open Science, Apr. 2024

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• Computational Mechanisms of Neuroimaging Biomarkers Uncovered by Multicenter Resting-State fMRI Connectivity Variation Profile

  Okito Yamashita; Ayumu Yamashita; Yuji Takahara; Yuki Sakai; Yasumasa Okamoto; Go Okada; Masahiro Takamura; Motoaki Nakamura; Takashi Itahashi; Takashi Hanakawa; Hiroki Togo; Yujiro Yoshihara; Toshiya Murai; Tomohisa Okada; Jin Narumoto; Hidehiko Takahashi; Haruto Takagishi; Koichi Hosomi; Kiyoto Kasai; Naohiro Okada; Osamu Abe; Hiroshi Imamizu; Takuya Hayashi; Shinsuke Koike; Saori C. Tanaka; Mitsuo Kawato

  02 Apr. 2024

  
• Seasonal Variations of Neuromotor Development By 14 Months of Age: Hamamatsu Birth Cohort for Mothers and Children (HBC Study)

  Kenji J. Tsuchiya; Hiroshi Tsutsumi; Kaori Matsumoto; Nori Takei; Makiko Narumiya; Maiko Honda; Ismail Thanseem; Ayyappan Anitha; Katsuaki Suzuki; Hideo Matsuzaki; Yasuhide Iwata; Kazuhiko Nakamura; Norio Mori

  PLoS ONE, 19 Dec. 2012, Peer-reviewed

  
• Psychosocial risk factors for postpartum depression and their relation to timing of onset: The Hamamatsu Birth Cohort (HBC) Study

  Tsuruko Mori; Kenji J. Tsuchiya; Kaori Matsumoto; Katsuaki Suzuki; Norio Mori; Nori Takei

  Journal of Affective Disorders, Dec. 2011, Peer-reviewed

  
• Age-specific 3-month cumulative incidence of postpartum depression: The Hamamatsu Birth Cohort (HBC) Study

  Kaori Matsumoto; Kenji J. Tsuchiya; Hiroaki Itoh; Naohiro Kanayama; Shiro Suda; Hideo Matsuzaki; Yasuhide Iwata; Katsuaki Suzuki; Kazuhiko Nakamura; Norio Mori; Nori Takei

  Journal of Affective Disorders, Oct. 2011, Peer-reviewed

  
• Psychosocial Determinants of Mistimed and Unwanted Pregnancy: The Hamamatsu Birth Cohort (HBC) Study

  Shun Takahashi; Kenji J. Tsuchiya; Kaori Matsumoto; Katsuaki Suzuki; Norio Mori; Nori Takei

  Maternal and Child Health Journal, 14 Sep. 2011, Peer-reviewed

  
• 著効例と工夫 間歇型一酸化炭素中毒による認知機能障害と錐体外路症状に対する高気圧酸素治療の有効性 一酸化炭素の洗い出し効果

  陣上 直人; 新田 孝幸; 吉原 雄二郎; 小林 勝哉; 石黒 義孝; 趙 晃済; 柚木 知之; 村井 俊哉; 高橋 良輔; 大鶴 繁

  日本高気圧環境・潜水医学会雑誌, Feb. 2023

  
• Generalizable neuromarker for autism spectrum disorder across imaging sites and developmental stages: A multi-site study.

  Takashi Itahashi; Ayumu Yamashita; Yuji Takahara; Noriaki Yahata; Motoaki Nakamura; Yuta Aoki; Ryuta Aoki; Junya Fujino; Haruhisa Ohta; Yujiro Yoshihara; Yuki Sakai; Masahiro Takamura; Naho Ichikawa; Go Okada; Naohiro Okada; Kiyoto Kasai; Saori Tanaka; Hiroshi Imamizu; Nobumasa Kato; Yasumasa Okamoto; Hidehiko Takahashi; Mitsuo Kawato; Okito Yamashita; Ryuichiro Hashimoto

  Research square, 15 May 2023

  
• Generalizable neuromarker for autism spectrum disorder across imaging sites and developmental stages: A multi-site study.

  Takashi Itahashi; Ayumu Yamashita; Yuji Takahara; Noriaki Yahata; Yuta Y Aoki; Junya Fujino; Yujiro Yoshihara; Motoaki Nakamura; Ryuta Aoki; Haruhisa Ohta; Yuki Sakai; Masahiro Takamura; Naho Ichikawa; Go Okada; Naohiro Okada; Kiyoto Kasai; Saori C Tanaka; Hiroshi Imamizu; Nobumasa Kato; Yasumasa Okamoto; Hidehiko Takahashi; Mitsuo Kawato; Okito Yamashita; Ryu-Ichiro Hashimoto

  bioRxiv : the preprint server for biology, 28 Mar. 2023

  
• Aberrant Large-Scale Network Interactions Across Psychiatric Disorders Revealed by Large-Sample Multi-Site Resting-State Functional Magnetic Resonance Imaging Datasets.

  Takuya Ishida; Yuko Nakamura; Saori C Tanaka; Yuki Mitsuyama; Satoshi Yokoyama; Hotaka Shinzato; Eri Itai; Go Okada; Yuko Kobayashi; Takahiko Kawashima; Jun Miyata; Yujiro Yoshihara; Hidehiko Takahashi; Susumu Morita; Shintaro Kawakami; Osamu Abe; Naohiro Okada; Akira Kunimatsu; Ayumu Yamashita; Okito Yamashita; Hiroshi Imamizu; Jun Morimoto; Yasumasa Okamoto; Toshiya Murai; Kiyoto Kasai; Mitsuo Kawato; Shinsuke Koike

  Schizophrenia bulletin, 09 Mar. 2023, Peer-reviewed

  
• Distinctive alterations in the mesocorticolimbic circuits in various psychiatric disorders

  Yuko Nakamura; Takuya Ishida; Saori C. Tanaka; Yuki Mitsuyama; Satoshi Yokoyama; Hotaka Shinzato; Eri Itai; Go Okada; Yuko Kobayashi; Takahiko Kawashima; Jun Miyata; Yujiro Yoshihara; Hidehiko Takahashi; Ryuta Aoki; Motoaki Nakamura; Haruhisa Ota; Takashi Itahashi; Susumu Morita; Shintaro Kawakami; Osamu Abe; Naohiro Okada; Akira Kunimatsu; Ayumu Yamashita; Okito Yamashita; Hiroshi Imamizu; Jun Morimoto; Yasumasa Okamoto; Toshiya Murai; Ryu‐Ichiro Hashimoto; Kiyoto Kasai; Mitsuo Kawato; Shinsuke Koike

  Psychiatry and Clinical Neurosciences, 11 Mar. 2023, Peer-reviewed

  
• Altered white matter microstructure and neurocognitive function of HIV-infected patients with low nadir CD4.

  Yujiro Yoshihara; Tadatsugu Kato; Dai Watanabe; Masaji Fukumoto; Keiko Wada; Naoya Oishi; Takahiro Nakakura; Keiko Kuriyama; Takuma Shirasaka; Toshiya Murai

  Journal of neurovirology, 01 Jul. 2022, Peer-reviewed

  
• Development of a classifier for gambling disorder based on functional connections between brain regions

  Hideaki Takeuchi; Noriaki Yahata; Giuseppe Lisi; Kosuke Tsurumi; Yujiro Yoshihara; Ryosaku Kawada; Takuro Murao; Hiroto Mizuta; Tatsunori Yokomoto; Takashi Miyagi; Yukako Nakagami; Toshinori Yoshioka; Junichiro Yoshimoto; Mitsuo Kawato; Toshiya Murai; Jun Morimoto; Hidehiko Takahashi

  Psychiatry and Clinical Neurosciences, 13 Mar. 2022, Peer-reviewed

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• Depressive symptoms reduce when dorsolateral prefrontal cortex-precuneus connectivity normalizes after functional connectivity neurofeedback.

  Jessica Elizabeth Taylor; Takashi Yamada; Takahiko Kawashima; Yuko Kobayashi; Yujiro Yoshihara; Jun Miyata; Toshiya Murai; Mitsuo Kawato; Tomokazu Motegi

  Scientific reports, 16 Feb. 2022, Peer-reviewed

  
• A multi-site, multi-disorder resting-state magnetic resonance image database.

  Saori C Tanaka; Ayumu Yamashita; Noriaki Yahata; Takashi Itahashi; Giuseppe Lisi; Takashi Yamada; Naho Ichikawa; Masahiro Takamura; Yujiro Yoshihara; Akira Kunimatsu; Naohiro Okada; Ryuichiro Hashimoto; Go Okada; Yuki Sakai; Jun Morimoto; Jin Narumoto; Yasuhiro Shimada; Hiroaki Mano; Wako Yoshida; Ben Seymour; Takeshi Shimizu; Koichi Hosomi; Youichi Saitoh; Kiyoto Kasai; Nobumasa Kato; Hidehiko Takahashi; Yasumasa Okamoto; Okito Yamashita; Mitsuo Kawato; Hiroshi Imamizu

  Scientific data, 30 Aug. 2021, Peer-reviewed

  
• Early and late effects of electroconvulsive therapy associated with different temporal lobe structures

  Shimpei Yamasaki; Toshihiko Aso; Jun Miyata; Genichi Sugihara; Masaaki Hazama; Kiyotaka Nemoto; Yujiro Yoshihara; Yukiko Matsumoto; Tomohisa Okada; Kaori Togashi; Toshiya Murai; Hidehiko Takahashi; Taro Suwa

  Translational Psychiatry, Dec. 2020, Peer-reviewed

  
• Cognition and interpersonal coordination of patients with schizophrenia who have sports habits

  Keisuke Fujii; Yujiro Yoshihara; Yukiko Matsumoto; Keima Tose; Hideaki Takeuchi; Masanori Isobe; Hiroto Mizuta; Daisuke Maniwa; Takehiko Okamura; Toshiya Murai; Yoshinobu Kawahara; Hidehiko Takahashi

  PLOS ONE, 09 Nov. 2020, Peer-reviewed

  
• Publisher Correction: Primary functional brain connections associated with melancholic major depressive disorder and modulation by antidepressants.

  Naho Ichikawa; Giuseppe Lisi; Noriaki Yahata; Go Okada; Masahiro Takamura; Ryu-Ichiro Hashimoto; Takashi Yamada; Makiko Yamada; Tetsuya Suhara; Sho Moriguchi; Masaru Mimura; Yujiro Yoshihara; Hidehiko Takahashi; Kiyoto Kasai; Nobumasa Kato; Shigeto Yamawaki; Ben Seymour; Mitsuo Kawato; Jun Morimoto; Yasumasa Okamoto

  Scientific reports, 14 Oct. 2020, Peer-reviewed

  
• Neurocognitive impairment and gray matter volume reduction in HIV-infected patients

  Tadatsugu Kato; Yujiro Yoshihara; Dai Watanabe; Masaji Fukumoto; Keiko Wada; Takahiro Nakakura; Keiko Kuriyama; Takuma Shirasaka; Toshiya Murai

  Journal of NeuroVirology, Aug. 2020, Peer-reviewed

  
• Overlapping but Asymmetrical Relationships Between Schizophrenia and Autism Revealed by Brain Connectivity.

  Yujiro Yoshihara; Giuseppe Lisi; Noriaki Yahata; Junya Fujino; Yukiko Matsumoto; Jun Miyata; Gen-Ichi Sugihara; Shin-Ichi Urayama; Manabu Kubota; Masahiro Yamashita; Ryuichiro Hashimoto; Naho Ichikawa; Weipke Cahn; Neeltje E M van Haren; Susumu Mori; Yasumasa Okamoto; Kiyoto Kasai; Nobumasa Kato; Hiroshi Imamizu; René S Kahn; Akira Sawa; Mitsuo Kawato; Toshiya Murai; Jun Morimoto; Hidehiko Takahashi

  Schizophrenia bulletin, 17 Apr. 2020, Peer-reviewed

  
• Primary functional brain connections associated with melancholic major depressive disorder and modulation by antidepressants.

  Naho Ichikawa; Giuseppe Lisi; Noriaki Yahata; Go Okada; Masahiro Takamura; Ryu-Ichiro Hashimoto; Takashi Yamada; Makiko Yamada; Tetsuya Suhara; Sho Moriguchi; Masaru Mimura; Yujiro Yoshihara; Hidehiko Takahashi; Kiyoto Kasai; Nobumasa Kato; Shigeto Yamawaki; Ben Seymour; Mitsuo Kawato; Jun Morimoto; Yasumasa Okamoto

  Scientific reports, 26 Feb. 2020, Peer-reviewed

  
• Harmonization of resting-state functional MRI data across multiple imaging sites via the separation of site differences into sampling bias and measurement bias

  Ayumu Yamashita; Noriaki Yahata; Takashi Itahashi; Giuseppe Lisi; Takashi Yamada; Naho Ichikawa; Masahiro Takamura; Yujiro Yoshihara; Akira Kunimatsu; Naohiro Okada; Hirotaka Yamagata; Koji Matsuo; Ryuichiro Hashimoto; Go Okada; Yuki Sakai; Jun Morimoto; Jin Narumoto; Yasuhiro Shimada; Kiyoto Kasai; Nobumasa Kato; Hidehiko Takahashi; Yasumasa Okamoto; Saori C. Tanaka; Mitsuo Kawato; Okito Yamashita; Hiroshi Imamizu

  PLoS Biology, 2019, Peer-reviewed

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• A prediction model of working memory across health and psychiatric disease using whole-brain functional connectivity

  Masahiro Yamashita; Yujiro Yoshihara; Ryuichiro Hashimoto; Noriaki Yahata; Naho Ichikawa; Yuki Sakai; Takashi Yamada; Noriko Matsukawa; Go Okada; Saori C. Tanaka; Kiyoto Kasai; Nobumasa Kato; Yasumasa Okamoto; Ben Seymour; Hidehiko Takahashi; Mitsuo Kawato; Hiroshi Imamizu

  eLife, 01 Dec. 2018, Peer-reviewed

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• Effect of phase-encoding direction on group analysis of resting-state functional magnetic resonance imaging.

  Mori Y; Miyata J; Isobe M; Son S; Yoshihara Y; Aso T; Kouchiyama T; Murai T; Takahashi H

  Psychiatry and clinical neurosciences, Sep. 2018, Peer-reviewed

  
• Additive Effect of Cigarette Smoking on Gray Matter Abnormalities in Schizophrenia.

  Naoto Yokoyama; Hitoshi Sasaki; Yasuo Mori; Miki Ono; Kousuke Tsurumi; Ryosaku Kawada; Yukiko Matsumoto; Yujiro Yoshihara; Genichi Sugihara; Jun Miyata; Toshiya Murai; Hidehiko Takahashi

  Schizophrenia bulletin, 06 Apr. 2018, Peer-reviewed

  
• Resting-State Functional Connectivity-Based Biomarkers and Functional MRI-Based Neurofeedback for Psychiatric Disorders: A Challenge for Developing Theranostic Biomarkers

  Takashi Yamada; Ryu-ichiro Hashimoto; Noriaki Yahata; Naho Ichikawa; Yujiro Yoshihara; Yasumasa Okamoto; Nobumasa Kato; Hidehiko Takahashi; Mitsuo Kawato

  INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, Oct. 2017, Peer-reviewed

  
• Ambiguity aversion in schizophrenia: An fMRI study of decision-making under risk and ambiguity.

  Junya Fujino; Kimito Hirose; Shisei Tei; Ryosaku Kawada; Kosuke Tsurumi; Noriko Matsukawa; Jun Miyata; Genichi Sugihara; Yujiro Yoshihara; Takashi Ideno; Toshihiko Aso; Kazuhisa Takemura; Hidenao Fukuyama; Toshiya Murai; Hidehiko Takahashi

  Schizophrenia research, Dec. 2016, Peer-reviewed

  
• Microglial Activation in Young Adults With Autism Spectrum Disorder

  Katsuaki Suzuki; Genichi Sugihara; Yasuomi Ouchi; Kazuhiko Nakamura; Masami Futatsubashi; Kiyokazu Takebayashi; Yujiro Yoshihara; Kei Omata; Kaori Matsumoto; Kenji J. Tsuchiya; Yasuhide Iwata; Masatsugu Tsujii; Toshirou Sugiyama; Norio Mori

  JAMA PSYCHIATRY, Jan. 2013, Peer-reviewed

  
• Effects of Brain Amyloid Deposition and Reduced Glucose Metabolism on the Default Mode of Brain Function in Normal Aging

  Mitsuru Kikuchi; Tetsu Hirosawa; Masamichi Yokokura; Shunsuke Yagi; Norio Mori; Etsuji Yoshikawa; Yujiro Yoshihara; Genichi Sugihara; Kiyokazu Takebayashi; Yasuhide Iwata; Katsuaki Suzuki; Kazuhiko Nakamura; Takatoshi Ueki; Yoshio Minabe; Yasuomi Ouchi

  JOURNAL OF NEUROSCIENCE, Aug. 2011, Peer-reviewed

  
• Plasma Cytokine Profiles in Subjects with High-Functioning Autism Spectrum Disorders

  Katsuaki Suzuki; Hideo Matsuzaki; Keiko Iwata; Yosuke Kameno; Chie Shimmura; Satomi Kawai; Yujiro Yoshihara; Tomoyasu Wakuda; Kiyokazu Takebayashi; Shu Takagai; Kaori Matsumoto; Kenji J. Tsuchiya; Yasuhide Iwata; Kazuhiko Nakamura; Masatsugu Tsujii; Toshirou Sugiyama; Norio Mori

  PLOS ONE, May 2011, Peer-reviewed

  
• Reduced Acetylcholinesterase Activity in the Fusiform Gyrus in Adults With Autism Spectrum Disorders

  Katsuaki Suzuki; Genichi Sugihara; Yasuomi Ouchi; Kazuhiko Nakamura; Masatsugu Tsujii; Masami Futatsubashi; Yasuhide Iwata; Kenji J. Tsuchiya; Kaori Matsumoto; Kiyokazu Takebayashi; Tomoyasu Wakuda; Yujiro Yoshihara; Shiro Suda; Mitsuru Kikuchi; Nori Takei; Toshirou Sugiyama; Toshiaki Irie; Norio Mori

  ARCHIVES OF GENERAL PSYCHIATRY, Mar. 2011, Peer-reviewed

  
• In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer's disease

  Masamichi Yokokura; Norio Mori; Shunsuke Yagi; Etsuji Yoshikawa; Mitsuru Kikuchi; Yujiro Yoshihara; Tomoyasu Wakuda; Genichi Sugihara; Kiyokazu Takebayashi; Shiro Suda; Yasuhide Iwata; Takatoshi Ueki; Kenji J. Tsuchiya; Katsuaki Suzuki; Kazuhiko Nakamura; Yasuomi Ouchi

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Feb. 2011, Peer-reviewed

  
• Progression from Unilateral to Bilateral Parkinsonism in Early Parkinson Disease: Implication of Mesocortical Dopamine Dysfunction by PET

  Shunsuke Yagi; Etsuji Yoshikawa; Masami Futatsubashi; Masamichi Yokokura; Yujiro Yoshihara; Tatsuo Torizuka; Yasuomi Ouchi

  JOURNAL OF NUCLEAR MEDICINE, Aug. 2010, Peer-reviewed

  
• Voxel-based structural magnetic resonance imaging (MRI) study of patients with early onset schizophrenia.

  Yujiro Yoshihara; Genichi Sugihara; Hideo Matsumoto; John Suckling; Katsuhiko Nishimura; Takao Toyoda; Haruo Isoda; Kenji J Tsuchiya; Kiyokazu Takebayashi; Katsuaki Suzuki; Harumi Sakahara; Kazuhiko Nakamura; Norio Mori; Nori Takei

  Annals of general psychiatry, 22 Dec. 2008, Peer-reviewed

  

Misc.

• 統合失調症患者の社会経済状況(Socioeconomic Status:SESと生活の質(QoL)との関連

  石塚美樹; 中神由香子; 中神由香子; 孫樹洛; 河島孝彦; 小林裕子; 大塚貞男; 久保田学; 鶴身考介; 吉原雄二郎; 村井俊哉; 宮田淳

  統合失調症研究, 2023

  
• Association between ”impending understanding” aspect of aberrant salience and temporal pole

  宮田淳; 中神由香子; 孫樹洛; 吉原雄二郎; 村井俊哉; 高橋英彦

  日本生物学的精神医学会(Web), 2023

  
• 統合失調症の認知とメタ認知に関わる神経ネットワークの解明

  小野田悠希; KIRK Geier; KIRK Geier; 中神由香子; 中神由香子; 五十嵐裕幸; 河島孝彦; 久良木悠介; 久保田学; 小林啓; 小林祐子; 佐々木仁; 孫樹洛; 堀朝樹; 三嶋亮; 水田弘人; 吉原雄二郎; 大石直也; 村井俊哉; 宮田淳

  統合失調症研究, 2022

  
• 間歇型一酸化炭素中毒による認知機能低下に対する高気圧酸素治療の有効性

  陣上 直人; 新田 孝幸; 川竹 絢子; 荒深 桜子; 橋本 健之; 堀 晃暢; 吉原 雄二郎; 小林 勝哉; 石黒 義孝; 趙 晃済; 柚木 知之; 村井 俊哉; 高橋 良輔; 大鶴 繁

  老年精神医学雑誌, Nov. 2022

  
• 間歇型一酸化炭素中毒に高気圧酸素治療が有効であった一例

  陣上 直人; 新田 孝幸; 吉原 雄二郎; 小林 勝哉; 石黒 義孝; 趙 晃済; 柚木 知之; 村井 俊哉; 高橋 良輔; 大鶴 繁

  日本救急医学会雑誌, Oct. 2022

  
• 間歇型一酸化炭素中毒による認知機能低下に対する高気圧酸素治療の有効性

  陣上 直人; 新田 孝幸; 川竹 絢子; 荒深 桜子; 橋本 健之; 堀 晃暢; 吉原 雄二郎; 小林 勝哉; 石黒 義孝; 趙 晃済; 柚木 知之; 村井 俊哉; 高橋 良輔; 大鶴 繁

  Dementia Japan, Oct. 2022

  
• 人工知能技術を用いた疾患判別法による統合失調症と自閉症スペクトラム障害の関係性

  吉原雄二郎

  精神科臨床legato / 「精神科臨床legato」編集委員会 編, Aug. 2021, Lead author

  
• 検査からみる神経疾患 MRSによる神経機能検査

  吉原雄二郎; 福山秀直

  Clinical Neuroscience（クリニカルニューロサイエンス）, Aug. 2019, Lead author

  
• Association between aberrant salience and ego-disturbance

  宮田淳; 中神由香子; 吉原雄二郎; 浅井智久; 大井博貴; 前田貴記; 村井俊哉; 高橋英彦; 高橋英彦

  日本生物学的精神医学会(Web), 2022

  
• HIV関連神経認知障害(HAND)と脳構造

  加藤賢嗣; 吉原雄二郎; 渡邊大; 福本真司; 和田恵子; 安尾利彦; 白阪琢磨; 村井俊哉

  日本エイズ学会誌, 20 Nov. 2018

  
• 脳科学で解き明かす精神神経症候 fMRIニューロフィードバツクの精神疾患への応用

  戸瀬景茉; 吉原雄二郎; 高橋英彦

  Brain and Nerve, 01 Nov. 2018

  
• FMRI Neurofeedback and its Application to Psychiatric Disorders

  戸瀨 景茉; 吉原 雄二郎; 高橋 英彦

  Brain and nerve, Nov. 2018

  
• 統合失調症における抗N‐methyl‐D‐aspartate receptor(NMDA‐R)抗体について

  中神由香子; 杉原玄一; 藤本岳; 川端美智子; 吉原雄二郎; 稲葉啓通; 岩田和彦; 白井隆光; 林拓二; 佐藤晋一; 蓑島豪智; 近藤誉之; 松本理器; 池田昭夫; 村井俊哉

  日本精神神経学会総会プログラム・抄録集, Jun. 2018

  
• 統合失調症における抗グルタミン酸受容体抗体価の検討

  杉原玄一; 中神由香子; 藤本岳; 川端美智子; 吉原雄二郎; 村井俊哉; 稲葉啓通; 岩田和彦; 白井隆光; 林拓二; 佐藤晋一; 蓑島豪智; 高橋幸利

  大和証券ヘルス財団研究業績集, Mar. 2018

  
• 複数精神疾患に渡って汎化する全脳結合作業記憶健常モデル

  山下真寛; 吉原雄二郎; 橋本龍一郎; 八幡憲明; 八幡憲明; 市川奈穂; 酒井雄希; 酒井雄希; 山田貴志; 山田貴志; 松河理子; 岡田剛; 田中沙織; 笠井清人; 加藤進昌; 岡本泰昌; SEYMOUR Ben; SEYMOUR Ben; SEYMOUR Ben; 高橋英彦; 川人光男; 川人光男; 今水寛; 今水寛; 今水寛

  日本ヒト脳機能マッピング学会プログラム・抄録集, 2017

  
• HIV感染症及びその合併症の課題を克服する研究 MRI画像による,神経認知障害の神経基盤の解明

  村井俊哉; 渡邊大; 安尾利彦; 下司有加; 東政美; 福本真司; 吉原雄二郎; 加藤賢嗣

  HIV感染症及びその合併症の課題を克服する研究 平成28年度 研究報告書(Web), 2017

  
• HIV感染症及びその合併症の課題を克服する研究 MRI画像による,神経認知障害の神経基盤の解明

  村井俊哉; 渡邊大; 安尾利彦; 下司有加; 東政美; 福本真司; 吉原雄二郎; 加藤賢嗣

  HIV感染症及びその合併症の課題を克服する研究 平成27年度 研究報告書, 2016

  
• 精神疾患の作業記憶能力を特徴づける機能的脳ネットワークの特異的変化(Uniquely altered functional brain networks characterize working memory ability in psychiatric disorders)

  山下 真寛; 吉原 雄二郎; 松河 理子; 高橋 英彦; 市川 奈穂; 岡本 泰昌; 加藤 進昌; 橋本 龍一郎; 八幡 憲明; 田中 沙織; 酒井 雄希; 川人 光男; 今水 寛

  日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集, Sep. 2015

  
• HIV感染症及びその合併症の課題を克服する研究 MRI画像による,神経認知障害の神経基盤の解明に関する研究

  村井俊哉; 仲倉高広; 安尾利彦; 鍛冶まどか; 渡邊大; 下司有加; 東政美; 福本真司; 吉原雄二郎; 加藤賢嗣

  HIV感染症及びその合併症の課題を克服する研究 平成26年度 研究報告書, 2015

  
• HIV感染症及びその合併症の課題を克服する研究 MRI画像による,神経認知障害の神経基盤の解明に関する研究

  村井俊哉; 仲倉高広; 安尾利彦; 鍛冶まどか; 渡邊大; 下司有加; 東政美; 福本真司; 吉原雄二郎; 加藤賢嗣

  HIV感染症及びその合併症の課題を克服する研究 平成24-26年度 総合研究報告書, 2015

  
• HIV感染症及びその合併症の課題を克服する研究 MRI画像による,神経認知障害の神経基盤の解明に関する研究

  村井俊哉; 仲倉高広; 鍛冶まどか; 渡邊大; 下司有加; 東政美; 福本真司; 吉原雄二郎; 加藤賢嗣

  HIV感染症及びその合併症の課題を克服する研究 平成25年度 研究報告書, 2014

  
• 難治性強迫性障害に対する森田療法と曝露反応妨害法の併用療法

  大隅香苗; 望月洋介; 近藤玲加; 橋詰由加里; 渡邊知子; 井上淳; 大城将也; 吉原雄二郎; 岩田泰秀

  月刊精神科, 28 Dec. 2010

  
• 強迫性障害に対する森田療法と暴露反応妨害法の併用療法の有用性

  近藤玲加; 大城将也; 吉原雄二郎; 望月洋介; 大隅香苗; 橋詰由加里; 岩田泰秀; 中村和彦; 森則夫

  精神神経学雑誌, 25 Aug. 2010

  
• 第1回統合失調症国際研究学会に参加して

  吉原 雄二郎; 武井 教使

  精神神經學雜誌 = Psychiatria et neurologia Japonica, 25 Aug. 2009, Lead author

  
• 若年発症の統合失調症の脳形態学的変化と臨床評価との関連

  吉原雄二郎; 杉原玄一; 松本英夫; SUCKLING John; 礒田治夫; 阪原晴海; 森則夫; 武井教使

  日本生物学的精神医学会プログラム・講演抄録, 2009

  
• 成人自閉症者における脳内コリン系機能~PETによる検討~

  鈴木勝昭; 杉原玄一; 吉原雄二郎; 横倉正倫; 中村和彦; 尾内康臣; 武井教使; 亀野陽亮; 森則夫

  日本脳科学会プログラム・講演抄録集, 2008

  

Presentations

• Differences between cognition and brain white matter of cART-treated HIV-infected patients with low and high CD4 nadir

  Yujiro Yoshihara; Tadatsugu Kato; Dai Watanabe; Takuma Shirasaka; Toshiya Murai

  Society for Neuroscience, Chicago, USA, 2019

  
• Functional connectivity-based neurofeedback for impaired working memory in schizophrenia

  Yujiro Yoshihara; Tomohisa Asai; Masahiro Yamashita; Takashi Yamada; Hiroshi Imamizu; Hidehiko Takahashi; Mitsuo Kawato

  real-time functional imaging and neurofeedback conference, Nara, Japan, 2017

  
• Schizophrenia biomarker using whole brain resting-state functional connectivity MRI: generalization to independent cohorts from different countries and disorder stages

  Yujiro Yoshihara

  Society for Neuroscience, Washington, USA, 2017

  
• Axonal Fiber Connectivity in Schizophrenia: A Graph Theoretical Analysis in a Japanese Sample

  Yujiro Yoshihara; Naoya Oishi; Genichi Sugihara; Toshiya Murai

  21st Annual Meeting of the Organization for Human Brain Mapping, Hawaii, USA, 2015

  
• Elevated Glutamatergic Metabolism in the Amygdala-Hippocampal Complex associated with Autism Spectrum Disorders

  Yujiro Yoshihara; Genichi Sugihara; Yasuomi Ouchi; Akira Ishizuka; Hideto Yogo; Kaori Matsumoto; Kenji J Tsuchiya; Nori Takei; Masatsugu Tsujii; Haruo Isoda; Kazuhiko Nakamura; Toshiro Sugiyama; Norio Mori

  International Society for Autism Research (INSAR) Annual Meeting, Toronto, Canada, 2012

  
• Discrimination of Autism Adults from Controls using Data on Structural MRI in a Japanese Sample

  Yujiro Yoshihara; Genichi Sugihara; Sean Deoni; Akira Ishizuka; Hideto Yogo; Kaori Matsumoto; Kenji J Tsuchiya; Masatsugu Tsujii; Kazuhiko Nakamura; Declan G Murphy; Norio Mori; Nori Takei

  Human Brain Mapping, Quebec, Canada, 2011

  
• Voxel-based structural MRI study of patients with early-onset schizophrenia

  Yujiro Yoshihara; Genichi Sugihara; John Suckling; Haruo Isoda; Harumi Sakahara; Norio Mori; Nori Takei

  The 1st Schizophrenia International Research Society Conference, Venice, Italy, 2008

  
• 若年発症の統合失調症の脳形態学的変化と臨床評価との関連

  吉原雄二郎; 杉原玄一; 武井教使; 礒田治夫; John Suckling; 阪原 晴海; 森則夫

  日本ヒト脳機能マッピング学会 10th Congress of Japan Human Brain Mapping Society, 山形, 2008

  
• Voxel-based structural MRI study of patients with early-onset schizophrenia

  Yujiro Yoshihara; Genichi Sugihara; John Suckling; Haruo Isoda; Harumi Sakahara; Norio Mori; Nori Takei

  The 12th Conference of Peace through Mind/Brain Science, Hamamatsu, Japan, 2008

  

External funds: Kakenhi

• 超高磁場MRによる脳内代謝物計測法の開発と病態フィンガープリントの解明

  Grant-in-Aid for Scientific Research (B)

  Basic Section 90110:Biomedical engineering-related

  Kyoto University

  岡田 知久

  From 01 Apr. 2021, To 31 Mar. 2024, Granted

  脳内代謝物質;MRスペクトロスコピー;超高磁場MR装置;病態バイオマーカー;脳内代謝物;超高磁場;超高磁場磁気共鳴装置;病態フィンガープリント

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21H03806/
• 7T MRSI・fMRSによる統合失調症のCCTCC障害仮説の検証

  Grant-in-Aid for Scientific Research (C)

  Basic Section 52030:Psychiatry-related

  Kyoto University

  吉原 雄二郎

  From 01 Apr. 2020, To 31 Mar. 2024, Granted

  統合失調症;スペクトロスコピー;グルタチオン;グルタミン酸;MRスペクトロスコピー

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K07919/
• Brain glutathione, structure, and blood flow in patients with schizophrenia

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Yujiro Yoshihara

  From 01 Apr. 2015, To 31 Mar. 2019, Project Closed

  グルタチオン;MRスペクトロスコピー;統合失調症;日内変動;グルタミン酸;スペクトロスコピー

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K09826/
• Protective and risk factors associated with progressive brain alterations in schizophrenia

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Genichi Sugihara

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  統合失調症;脳画像

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K09825/
• Neural networks underlying social cognitive impairment in schizophrenia and their plasticity

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Toshiya Murai

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  神経科学;臨床

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H04893/
• 高機能自閉症者の軸策走行異常と活性型ミクログリア

  Grant-in-Aid for Scientific Research (C)

  Hamamatsu University School of Medicine

  吉原 雄二郎

  From 01 Apr. 2013, To 31 Mar. 2014, Declined

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25461761/
• Abnormal activation and alterations in neuron density and neurotransmitters in the default mode network in autism

  Grant-in-Aid for Scientific Research (C)

  Hamamatsu University School of Medicine

  Kei OMATA

  From 01 Apr. 2012, To 31 Mar. 2015, Project Closed

  自閉症;脳構造;MRS;デフォルトモードネットワーク;顔認知;紡錘状回;脳機能;国際情報交換

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24591701/
• Clarification of pathophysiology of autism related to single-incidence family and multiple-incidence families by combining brain imaging study and CNV analysis study

  Grant-in-Aid for Scientific Research (B)

  Hirosaki University;Hamamatsu University School of Medicine

  KAZUHIKO NAKAMURA

  From 01 Apr. 2011, To 31 Mar. 2014, Project Closed

  児童・思春期精神医学;自閉症;CNV解析;トリオサンプル;CNV

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23390288/
• Glutamate concentration in the brain of individuals with autism: A proton magnetic resonance spectroscopy study.

  Grant-in-Aid for Scientific Research (C)

  Hamamatsu University School of Medicine

  Yujiro YOSHIHARA

  From 01 Apr. 2010, To 31 Mar. 2013, Project Closed

  児童;思春期精神医学;分子イメージング;自閉症;磁気共鳴スペクトル法;グルタミン酸;脳構造;拡散テンソル画像法;MRS;拡散強調画像;核磁気共鳴スペクトロスコピー;拡散強調テンソル画像

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22591281/
• Frontal lobe abnormalities in alcoholics: a multimodal molecular imaging study

  Grant-in-Aid for Scientific Research (C)

  Hamamatsu University School of Medicine

  Yasuhide IWATA

  From 01 Apr. 2010, To 31 Mar. 2013, Project Closed

  中毒性精神障害;アルコール依存;分子イメージング;アルコール依存症;前頭葉傷害;ALDH2;活性型ミクログリア;PET;DTI;CANTAB

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22591258/
• Molecular imaging of cholinergic system in the brain of autism: A positron emission tomography study.

  Grant-in-Aid for Scientific Research (B)

  Hamamatsu University School of Medicine

  Katsuaki SUZUKI

  From 01 Apr. 2010, To 31 Mar. 2013, Project Closed

  児童・思春期精神医学;分子イメージング;コリンエステラーゼ;PET;自閉症;陽電子断層法;アセチルコリンエステラーゼ;広汎性発達障害;紡錘状回

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22390221/
• An epidemiological study of mental health in children and neuroimaging investigation : in view of social and emotional developments

  Grant-in-Aid for Scientific Research (B)

  Hamamatsu University School of Medicine

  Noriyoshi TAKEI

  From 01 Apr. 2007, To 31 Mar. 2010, Project Closed

  子ども;メンタルヘルス;社会性;疫学;脳発達;自閉症;脳画像

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19390303/