Basic Information

Faculty

• 薬学部

Professional Memberships

• 日本細胞外小胞学会

Academic Degree

• 修士（薬学）(京都大学)
• 博士（薬学）(京都大学)

Research History

• From Apr. 2009

  Kyoto University, Assistant professor
• From Apr. 2008

  University of Pittsburgh, Postodoctral research associate
• -, -

Profile

• Profile

  Main field of my research is biopharmaceutics, especially in the development of drug delivery system. Regarding to education, my goal is to help graduate students acquire the aboility of thinking and practical skills needed to perform research by my guidance.

Language of Instruction

• English

ID,URL

• ORCID ID

  0000-0002-8772-2772

• J-Global ID

  201401058285757017

researchmap URL

• https://researchmap.jp/ytakahashi0125

Research

Research Topics, Overview of the research

• Research Topics

  Development of therapeutic system by DDS of nucleic acids and genes

• Overview of the research

  I started my research based on the consideration that gene therapy and oligonucleotide-based therapy can be an effective therapeutic treatment against refractory disease. To improve therapeutic effect in gene therapy, I designed the vector encoding therapeutic protein. Recently, my research focuses on the development of delivery system using cell-derived small particles such as exosomes.

Research Interests

• Biopharmaceutics, Drug delivery system, Gene therapy, Extracellular vesicle, Exosome

Research Areas

• Life sciences, Biomedical engineering

Papers

• Development of a simple labeling method using fluorescent protein fusion proteins targeting the membrane lipids of small extracellular vesicles

  Yuki Kobayashi; Yuki Takahashi; Hiroto Otera; Yuriko Higuchi; Yoshinobu Takakura

  Journal of Pharmaceutical and Biomedical Analysis, May 2026

  
• Development of Ribityllumazine Analogue as Mucosal-Associated Invariant T Cell Ligands.

  Ryosuke Takasaki; Emi Ito; Masamichi Nagae; Yuki Takahashi; Takuro Matsuoka; Wakana Yasue; Norihito Arichi; Hiroaki Ohno; Sho Yamasaki; Shinsuke Inuki

  Journal of the American Chemical Society, 21 Oct. 2024

  
• Development of immunotherapy using extracellular vesicles

  Yuki Takahashi; Yoshinobu Takakura

  Drug Delivery System, 2021

  
• Exosomes in cancer immunotherapy

  Yuki Takahashi; Yoshinobu Takakura

  Diagnostic and Therapeutic Applications of Exosomes in Cancer, 01 Jan. 2018

  
• Erratum to ‘Preservation of exosomes at room temperature using lyophilization’ (International Journal of Pharmaceutics (2018) 553(1–2) (1–7), (S0378517318307671) (10.1016/j.ijpharm.2018.10.032))

  Chonlada Charoenviriyakul; Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  International Journal of Pharmaceutics, 25 Mar. 2019

  
• Development of exosome-based DDS targeting gastrointestinal cancer

  Yuki Takahashi; Yoshinobu Takakura

  Drug Delivery System, 25 Nov. 2018

  
• インターフェロン持続発現プラスミドを利用した直接作用型抗ウイルス薬耐性C型肝炎ウイルス感染に対するインターフェロン遺伝子治療

  浜名 温志; 高橋 有己; 内田 宅郎; 西川 元也; 今村 道雄; 茶山 一彰; 高倉 喜信

  日本DDS学会学術集会プログラム予稿集, Jun. 2017

  
• Multivalent dendritic DNA aptamer molecules for the enhancement of therapeutic effect

  Yusuke Kawamoto; You Wu; Soyoung Park; Kumi Hidaka; Hiroshi Sugiyama; Yuki Takahashi; Yoshinobu Takakura

  Chemical Communications, 2024

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• Development of Enzymatic Depletion Methods for Preparation of Small Extracellular Vesicles with Long Blood-Circulation Half-Life

  Yuki Kobayashi; Shimpei Kitamura; Yuki Takahashi; Yoshinobu Takakura

  Pharmaceutical Research, 04 Oct. 2022

  
• Development of potent unmethylated CpG DNA hydrogel by introducing i-motifs into long single-stranded DNA

  Wakana Oda; Keisuke Umemura; Koichi Ito; Yusuke Kawamoto; Yuki Takahashi; Yoshinobu Takakura

  International Journal of Pharmaceutics, Sep. 2023

  
• The identification of novel small extracellular vesicle (sEV) production modulators using luciferase‐based sEV quantification method

  Aki Yamamoto; Yuki Takahashi; Shinsuke Inuki; Shumpei Nakagawa; Kodai Nakao; Hiroaki Ohno; Masao Doi; Yoshinobu Takakura

  Journal of Extracellular Biology, 27 Sep. 2022, Peer-reviewed

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• Pharmacokinetic Approach for the Elucidation of Elevated Plasma Small Extracellular Vesicle (sEV) Concentration in Cancer.

  Aki Yamamoto; Mihiro Toba; Yuki Takahashi; Yoshinobu Takakura

  Journal of pharmaceutical sciences, Jul. 2023

  
• Development of Nucleic Acid Medicines Based on Chemical Technology

  Yusuke Kawamoto; You Wu; Yuki Takahashi; Yoshinobu Takakura

  Advanced Drug Delivery Reviews, May 2023

  
• Drug-preloadable methacrylated gelatin microspheres fabricated using an aqueous two-phase system

  Yuya Mizukami; Takuma Yamaguchi; Miki Shiono; Yuki Takahashi; Kazunori Shimizu; Satoshi Konishi; Yoshinobu Takakura; Makiya Nishikawa

  European Polymer Journal, Dec. 2022

  
• Development of Hydrophobic Interaction-based DNA Supramolecules as Efficient Delivery Carriers of CpG DNA to Immune cells.

  Koichi Ito; Mustumi Kariya; Kento Yasui; Yuki Takahashi; Yoshinobu Takakura

  Journal of pharmaceutical sciences, Apr. 2022

  
• Interleukin-4-carrying small extracellular vesicles with a high potential as anti-inflammatory therapeutics based on modulation of macrophage function.

  Misako Takenaka; Ayane Yabuta; Yuki Takahashi; Yoshinobu Takakura

  Biomaterials, Nov. 2021

  
• Development of allergic rhinitis immunotherapy using antigen-loaded small extracellular vesicles.

  Wen Liu; Maki Ota; Mayu Tabushi; Yuki Takahashi; Yoshinobu Takakura

  Journal of controlled release : official journal of the Controlled Release Society, May 2022

  
• Enhanced Immunostimulatory Activity of Covalent DNA Dendrons

  Yusuke Kawamoto; Wen Liu; Ji Hye Yum; Soyoung Park; Hiroshi Sugiyama; Yuki Takahashi; Yoshinobu Takakura

  ChemBioChem, 08 Dec. 2021

  
• Calcium Peroxide-Containing Polydimethylsiloxane-Based Microwells for Inhibiting Cell Death in Spheroids through Improved Oxygen Supply

  Yuya Mizukami; Yuki Takahashi; Kazunori Shimizu; Satoshi Konishi; Yoshinobu Takakura; Makiya Nishikawa

  Biological and Pharmaceutical Bulletin, 01 Oct. 2021

  
• Phosphatidylserine-deficient small extracellular vesicle is a major somatic cell-derived sEV subpopulation in blood.

  Akihiro Matsumoto; Yuki Takahashi; Kosuke Ogata; Shimpei Kitamura; Naoki Nakagawa; Aki Yamamoto; Yasushi Ishihama; Yoshinobu Takakura

  iScience, 20 Aug. 2021

  
• Determining the role of surface glycans in the pharmacokinetics of small extracellular vesicles.

  Aki Yamamoto; Yukari Yasue; Yuki Takahashi; Yoshinobu Takakura

  Journal of pharmaceutical sciences, 03 Jun. 2021

  
• Critical contribution of macrophage scavenger receptor 1 to the uptake of nanostructured DNA by immune cells.

  Keisuke Umemura; Shozo Ohtsuki; Makoto Nagaoka; Kosuke Kusamori; Takao Inoue; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  Nanomedicine : nanotechnology, biology, and medicine, Jun. 2021

  
• Combined use of chemically modified nucleobases and nanostructured DNA for enhanced immunostimulatory activity of CpG oligodeoxynucleotide.

  Yuki Araie; Shozo Ohtsuki; Soyoung Park; Makoto Nagaoka; Keisuke Umemura; Hiroshi Sugiyama; Kosuke Kusamori; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  Bioorganic & medicinal chemistry, 01 Jan. 2021

  
• Intercellular delivery of NF-κB inhibitor peptide utilizing small extracellular vesicles for the application of anti-inflammatory therapy.

  Misako Takenaka; Yuki Takahashi; Yoshinobu Takakura

  Journal of controlled release : official journal of the Controlled Release Society, 10 Dec. 2020

  
• Antitumor immunity by small extracellular vesicles collected from activated dendritic cells through effective induction of cellular and humoral immune responses.

  Akihiro Matsumoto; Maho Asuka; Yuki Takahashi; Yoshinobu Takakura

  Biomaterials, Sep. 2020, Peer-reviewed

  
• DNA density-dependent uptake of DNA origami-based two-or three-dimensional nanostructures by immune cells.

  Tatsuoki Maezawa; Shozo Ohtsuki; Kumi Hidaka; Hiroshi Sugiyama; Masayuki Endo; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  Nanoscale, 16 Jul. 2020, Peer-reviewed

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• Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice.

  Yuto Nakamura; Shunbun Kita; Yoshimitsu Tanaka; Shiro Fukuda; Yoshinari Obata; Tomonori Okita; Hiroyuki Nishida; Yuki Takahashi; Yusuke Kawachi; Yuri Tsugawa-Shimizu; Yuya Fujishima; Hitoshi Nishizawa; Yoshinobu Takakura; Shigeru Miyagawa; Yoshiki Sawa; Norikazu Maeda; Iichiro Shimomura

  Molecular therapy : the journal of the American Society of Gene Therapy, 08 Jul. 2020, Peer-reviewed

  
• Development of CD40L-modified tumor small extracellular vesicles for effective induction of antitumor immune response.

  Wen Liu; Yuki Takahashi; Masaki Morishita; Makiya Nishikawa; Yoshinobu Takakura

  Nanomedicine (London, England), Jul. 2020, Peer-reviewed

  
• Development of RNA/DNA Hydrogel Targeting Toll-Like Receptor 7/8 for Sustained RNA Release and Potent Immune Activation.

  Fusae Komura; Kana Okuzumi; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  Molecules (Basel, Switzerland), 07 Feb. 2020, Peer-reviewed

  
• Analysis of Tertiary Structural Features of Branched DNA Nanostructures with Partially Common Sequences Using Small-Angle X-ray Scattering

  Mengmeng Tan; Natsuki Takahashi; Shota Fujii; Kazuo Sakurai; Kosuke Kusamori; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  ACS Applied Bio Materials, 21 Jan. 2020, Peer-reviewed

  
• Incorporation of Gelatin Microspheres into HepG2 Human Hepatocyte Spheroids for Functional Improvement through Improved Oxygen Supply to Spheroid Core.

  Yuya Mizukami; Ai Moriya; Yuki Takahashi; Kazunori Shimizu; Satoshi Konishi; Yoshinobu Takakura; Makiya Nishikawa

  Biological & pharmaceutical bulletin, 2020

  
• Therapeutic Application of Small Extracellular Vesicles (sEVs): Pharmaceutical and Pharmacokinetic Challenges.

  Yoshinobu Takakura; Akihiro Matsumoto; Yuki Takahashi

  Biological & pharmaceutical bulletin, 2020, Peer-reviewed

  
• Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance.

  Matsumoto A; Takahashi Y; Chang HY; Wu YW; Yamamoto A; Ishihama Y; Takakura Y

  Journal of extracellular vesicles, 2020, Peer-reviewed

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• Folding of single-stranded circular DNA into rigid rectangular DNA accelerates its cellular uptake.

  Shozo Ohtsuki; Yukako Shiba; Tatsuoki Maezawa; Kumi Hidaka; Hiroshi Sugiyama; Masayuki Endo; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  Nanoscale, 28 Dec. 2019, Peer-reviewed

  
• Development of DNA-anchored assembly of small extracellular vesicle for efficient antigen delivery to antigen presenting cells.

  Matsumoto A; Takahashi Y; Ariizumi R; Nishikawa M; Takakura Y

  Biomaterials, Dec. 2019, Peer-reviewed

  
• Development of a Nanostructured RNA/DNA Assembly as an Adjuvant Targeting Toll-Like Receptor 7/8

  Fusae Komura; Yuki Takahashi; Takao Inoue; Yoshinobu Takakura; Makiya Nishikawa

  Nucleic Acid Therapeutics, 01 Dec. 2019, Peer-reviewed

  
• Effects of Localization of Antigen Proteins in Antigen-Loaded Exosomes on Efficiency of Antigen Presentation.

  Arima Y; Liu W; Takahashi Y; Nishikawa M; Takakura Y

  Molecular pharmaceutics, Jun. 2019, Peer-reviewed

  
• Regulation of the Distribution of Cells in Mixed Spheroids by Altering Migration Direction.

  Mizukami Y; Takahashi Y; Shimizu K; Konishi S; Takakura Y; Nishikawa M

  Tissue engineering. Part A, Mar. 2019, Peer-reviewed

  
• Preservation of exosomes at room temperature using lyophilization.

  Charoenviriyakul C; Takahashi Y; Nishikawa M; Takakura Y

  International journal of pharmaceutics, Dec. 2018, Peer-reviewed

  
• Combined encapsulation of a tumor antigen and immune cells using a self-assembling immunostimulatory DNA hydrogel to enhance antigen-specific tumor immunity.

  Umeki Y; Saito M; Kusamori K; Tsujimura M; Nishimura M; Takahashi Y; Takakura Y; Nishikawa M

  Journal of controlled release : official journal of the Controlled Release Society, Oct. 2018, Peer-reviewed

  
• Development of orally-deliverable DNA hydrogel by microemulsification and chitosan coating

  Daiki Nomura; Masaaki Saito; Yosuke Takahashi; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  International Journal of Pharmaceutics, 25 Aug. 2018, Peer-reviewed

  
• Possibility of Exosome-Based Therapeutics and Challenges in Production of Exosomes Eligible for Therapeutic Application

  Takuma Yamashita; Yuki Takahashi; Yoshinobu Takakura

  Biological and Pharmaceutical Bulletin, 01 Jun. 2018, Peer-reviewed

  
• Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice

  Yosuke Takahashi; Yuki Araie; Daiki Nomura; Yuki Takahashi; Kohei Sano; Hideo Saji; Yoshinobu Takakura; Makiya Nishikawa

  Journal of Drug Targeting, 21 Apr. 2018, Peer-reviewed

  
• Role of Extracellular Vesicle Surface Proteins in the Pharmacokinetics of Extracellular Vesicles.

  Chonlada Charoenviriyakul; Yuki Takahashi; Masaki Morishita; Makiya Nishikawa; Yoshinobu Takakura

  Molecular pharmaceutics, 05 Mar. 2018, Peer-reviewed

  
• Safe and effective interferon-beta gene therapy for the treatment of multiple sclerosis by regulating biological activity through the design of interferon-beta-galectin-9 fusion proteins

  Atsushi Hamana; Yuki Takahashi; Akane Tanioka; Makiya Nishikawa; Yoshinobu Takakura

  International Journal of Pharmaceutics, 30 Jan. 2018, Peer-reviewed

  
• Control of polarization and tumoricidal activity of macrophages by multicellular spheroid formation

  Yutaro Tanaka; Makiya Nishikawa; Yuya Mizukami; Kosuke Kusamori; Yuka Ogino; Shunsuke Nishimura; Kazunori Shimizu; Satoshi Konishi; Yuki Takahashi; Yoshinobu Takakura

  Journal of Controlled Release, 28 Jan. 2018, Peer-reviewed

  
• Enhanced activity of immunosuppressive oligodeoxynucleotides by incorporating them into hexapod-like nanostructured DNA

  Yuki Araie; Yosuke Takahashi; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  Biological and Pharmaceutical Bulletin, 2018, Peer-reviewed

  
• Screening of Exosome-Tropic RNA

  Takuma Yamashita; Haruka Shinotsuka; Yuki Takahashi; Kana Kato; Makiya Nishikawa; Yoshinobu Takakura

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Dec. 2017, Peer-reviewed

  
• Elucidation of the Mechanism of Increased Activity of Immunostimulatory DNA by the Formation of Polypod-like Structure

  Kohta Mohri; Kengo Nagata; Shozo Ohtsuki; Shiori Toyama; Mao Nonomura; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa; Shinji Sakuma

  PHARMACEUTICAL RESEARCH, Nov. 2017, Peer-reviewed

  
• DNA nanotechnology-based composite-type gold nanoparticle-immunostimulatory DNA hydrogel for tumor photothermal immunotherapy

  Tomoya Yata; Yuki Takahashi; Mengmeng Tan; Hirotaka Nakatsuji; Shozo Ohtsuki; Tatsuya Murakami; Hiroshi Imahori; Yuka Umeki; Tomoki Shiomi; Yoshinobu Takakura; Makiya Nishikawa

  BIOMATERIALS, Nov. 2017, Peer-reviewed

  
• Enhanced Class I Tumor Antigen Presentation via Cytosolic Delivery of Exosomal Cargos by Tumor-Cell-Derived Exosomes Displaying a pH-Sensitive Fusogenic Peptide

  Masaki Morishita; Yuki Takahashi; Makiya Nishikawa; Reiichi Ariizumi; Yoshinobu Takakura

  MOLECULAR PHARMACEUTICS, Nov. 2017, Peer-reviewed

  
• Retardation of Antigen Release from DNA Hydrogel Using Cholesterol-Modified DNA for Increased Antigen-Specific Immune Response

  Yuka Umeki; Masaaki Saito; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  ADVANCED HEALTHCARE MATERIALS, Oct. 2017, Peer-reviewed

  
• Evaluation of antiviral effect of type I, II, and III interferons on direct-acting antiviral-resistant hepatitis C virus

  Atsushi Hamana; Yuki Takahashi; Takuro Uchida; Makiya Nishikawa; Michio Imamura; Kazuaki Chayama; Yoshinobu Takakura

  ANTIVIRAL RESEARCH, Oct. 2017, Peer-reviewed

  
• Reconstruction of Toll-like receptor 9-mediated responses in HEK-Blue hTLR9 cells by transfection of human macrophage scavenger receptor 1 gene

  Shozo Ohtsuki; Yuki Takahashi; Takao Inoue; Yoshinobu Takakura; Makiya Nishikawa

  SCIENTIFIC REPORTS, Oct. 2017, Peer-reviewed

  
• Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells

  Akihiro Matsumoto; Yuki Takahashi; Makiya Nishikawa; Kohei Sano; Masaki Morishita; Chonlada Charoenviriyakul; Hideo Saji; Yoshinobu Takakura

  CANCER SCIENCE, Sep. 2017, Peer-reviewed

  
• Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells.

  Akihiro Matsumoto; Yuki Takahashi; Makiya Nishikawa; Kohei Sano; Masaki Morishita; Chonlada Charoenviriyakul; Hideo Saji; Yoshinobu Takakura

  Cancer science, Sep. 2017, Peer-reviewed

  
• Pharmacokinetics of Exosomes-An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics

  Masaki Morishita; Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Sep. 2017, Peer-reviewed

  
• In Vitro and In Vivo Stimulation of Toll-Like Receptor 9 by CpG Oligodeoxynucleotides Incorporated Into Polypod-Like DNA Nanostructures

  Yosuke Takahashi; Tatsuoki Maezawa; Yuki Araie; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  JOURNAL OF PHARMACEUTICAL SCIENCES, Sep. 2017, Peer-reviewed

  
• Using size-controlled multicellular spheroids of murine adenocarcinoma cells to efficiently establish pulmonary tumors in mice

  Tomoko Nishikawa; Yutaro Tanaka; Kosuke Kusamori; Narumi Mizuno; Yuya Mizukami; Yuka Ogino; Kazunori Shimizu; Satoshi Konishi; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  BIOTECHNOLOGY JOURNAL, Aug. 2017, Peer-reviewed

  
• Amelioration of Experimental Autoimmune Encephalomyelitis in Mice by Interferon-Beta Gene Therapy, Using a Long-Term Expression Plasmid Vector

  Atsushi Hamana; Yuki Takahashi; Akane Tanioka; Makiya Nishikawa; Yoshinobu Takakura

  MOLECULAR PHARMACEUTICS, Apr. 2017, Peer-reviewed

  
• Targeted Delivery of Interferon Gamma Using a Recombinant Fusion Protein of a Fibrin Clot-Binding Peptide With Interferon Gamma for Cancer Gene Therapy

  Mitsuru Ando; Mai Fujimoto; Yuki Takahashi; Makiya Nishikawa; Atsushi Hamana; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Mar. 2017, Peer-reviewed

  
• Optimization of Albumin Secretion and Metabolic Activity of Cytochrome P450 1A1 of Human Hepatoblastoma HepG2 Cells in Multicellular Spheroids by Controlling Spheroid Size

  Tomoko Nishikawa; Yutaro Tanaka; Makiya Nishikawa; Yuka Ogino; Kosuke Kusamori; Narumi Mizuno; Yuya Mizukami; Kazunori Shimizu; Satoshi Konishi; Yuki Takahashi; Yoshinobu Takakura

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Mar. 2017, Peer-reviewed

  
• In Vivo Tracking of Extracellular Vesicles in Mice Using Fusion Protein Comprising Lactadherin and Gaussia Luciferase.

  Takahashi Y; Nishikawa M; Takakura Y

  Methods in molecular biology (Clifton, N.J.), 2017, Peer-reviewed

  
• Role of Phosphatidylserine-Derived Negative Surface Charges in the Recognition and Uptake of Intravenously Injected B16BL6-Derived Exosomes by Macrophages

  Akihiro Matsumoto; Yuki Takahashi; Makiya Nishikawa; Kohei Sano; Masaki Morishita; Chonlada Charoenviriyakul; Hideo Saji; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Jan. 2017, Peer-reviewed

  
• Improved sustained release of antigen from immunostimulatory DNA hydrogel by electrostatic interaction with chitosan

  Yumiko Ishii-Mizuno; Yuka Umeki; Yoshinori Onuki; Hiroshi Watanabe; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  INTERNATIONAL JOURNAL OF PHARMACEUTICS, Jan. 2017, Peer-reviewed

  
• Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics

  Chonlada Charoenviriyakul; Yuki Takahashi; Masaki Morishita; Akihiro Matsumoto; Makiya Nishikawa; Yoshinobu Takakura

  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Jan. 2017, Peer-reviewed

  
• Exosome-based tumor antigens-adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA

  Masaki Morishita; Yuki Takahashi; Akihiro Matsumoto; Makiya Nishikawa; Yoshinobu Takakura

  BIOMATERIALS, Dec. 2016, Peer-reviewed

  
• Interferon-Inducible Mx Promoter-Driven, Long-Term Transgene Expression System of Interferon-beta for Cancer Gene Therapy

  Atsushi Hamana; Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  HUMAN GENE THERAPY, Nov. 2016, Peer-reviewed

  
• Effects of transgene expression level per cell in mice livers on induction of transgene-specific immune responses after hydrodynamic gene transfer

  Y. Yin; Y. Takahashi; A. Hamana; M. Nishikawa; Y. Takakura

  GENE THERAPY, Jul. 2016, Peer-reviewed

  
• Depressive symptoms as a side effect of Interferon-alpha therapy induced by induction of indoleamine 2,3-dioxygenase 1

  Yuki Murakami; Takaaki Ishibashi; Eiichi Tomita; Yukio Imamura; Tomoyuki Tashiro; Kanitta Watcharanurak; Makiya Nishikawa; Yuki Takahashi; Yoshinobu Takakura; Satoko Mitani; Hidetsugu Fujigaki; Yoshiji Ohta; Hisako Kubo; Takayoshi Mamiya; Toshitaka Nabeshima; Hyoung-Chun Kim; Yasuko Yamamoto; Kuniaki Saito

  SCIENTIFIC REPORTS, Jul. 2016, Peer-reviewed

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• エキソソームのマクロファージによる取り込みにおけるホスファチジルセリンの関与

  松本 明宏; 高橋 有己; 佐野 紘平; 森下 将輝; Charoenviriyakul Chonlada; 西川 元也; 佐治 英郎; 高倉 喜信

  日本薬学会年会要旨集, Mar. 2016

  
• Application of Magnesium Pyrophosphate-Based Sponge-Like Microparticles to Enhance the Delivery Efficiency and Adjuvant Effects of Polyriboinosinic-Polyribocytidylic Acid in Immune Cells

  Shoichi Takagi; Yuki Takahashi; Kanako Sugimura; Makiya Nishikawa; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Feb. 2016, Peer-reviewed

  
• Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells

  Yu Nishida; Shozo Ohtsuki; Yuki Araie; Yuka Umeki; Masayuki Endo; Tomoko Emura; Kumi Hidaka; Hiroshi Sugiyama; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, Jan. 2016, Peer-reviewed

  
• Erratum: Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion (Scientific Reports (2015) 5 (14979) DOI: 10.1038/srep14979)

  Yata T; Takahashi Y; Tan M; Hidaka K; Sugiyama H; Endo M; Takakura Y; Nishikawa M

  Scientific Reports, Jan. 2016, Peer-reviewed

  
• Effect of exosome isolation methods on physicochemical properties of exosomes and clearance of exosomes from the blood circulation

  Takuma Yamashita; Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, Jan. 2016, Peer-reviewed

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• Analysis and Control of in Vivo Kinetics of Exosomes for the Development of Exosome-based DDS

  Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Jan. 2016, Peer-reviewed

  
• Increased Insulin Secretion from Insulin-Secreting Cells by Construction of Mixed Multicellular Spheroids

  Kosuke Kusamori; Makiya Nishikawa; Narumi Mizuno; Tomoko Nishikawa; Akira Masuzawa; Yutaro Tanaka; Yuya Mizukami; Kazunori Shimizu; Satoshi Konishi; Yuki Takahashi; Yoshinobu Takakura

  PHARMACEUTICAL RESEARCH, Jan. 2016, Peer-reviewed

  
• Atomic force microscopy analysis of orientation and bending of oligodeoxynucleotides in polypod-like structured DNA

  Tomoki Shiomi; Mengmeng Tan; Natsuki Takahashi; Masayuki Endo; Tomoko Emura; Kumi Hidaka; Hiroshi Sugiyama; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  NANO RESEARCH, Dec. 2015, Peer-reviewed

  
• Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion

  Tomoya Yata; Yuki Takahashi; Mengmeng Tan; Kumi Hidaka; Hiroshi Sugiyama; Masayuki Endo; Yoshinobu Takakura; Makiya Nishikawa

  SCIENTIFIC REPORTS, Oct. 2015, Peer-reviewed

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• Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells

  Shozo Ohtsuki; Noriyuki Matsuzaki; Kohta Mohri; Masayuki Endo; Tomoko Emura; Kumi Hidaka; Hiroshi Sugiyama; Yuki Takahashi; Kenichi Ishiyama; Norimitsu Kadowaki; Yoshinobu Takakura; Makiya Nishikawa

  NUCLEIC ACID THERAPEUTICS, Oct. 2015, Peer-reviewed

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• Induction of Potent Antitumor Immunity by Sustained Release of Cationic Antigen from a DNA-Based Hydrogel with Adjuvant Activity

  Yuka Umeki; Kohta Mohri; Yohji Kawasaki; Hiroshi Watanabe; Rei Takahashi; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  ADVANCED FUNCTIONAL MATERIALS, Sep. 2015, Peer-reviewed

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• Contribution of epigenetic modifications to the decline in transgene expression from plasmid DNA in mouse liver

  Lei Zang; Makiya Nishikawa; Mitsuru Ando; Yuki Takahashi; Yoshinobu Takakura

  Pharmaceutics, 09 Aug. 2015, Peer-reviewed

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• Self-Assembling DNA Dendrimer for Effective Delivery of Immunostimulatory CpG DNA to Immune Cells

  Kohta Mohri; Eri Kusuki; Shozo Ohtsuki; Natsuki Takahashi; Masayuki Endo; Kumi Hidaka; Hiroshi Sugiyama; Yuki Takahashi; Yoshinobu Takakura; Makiya Nishikawa

  BIOMACROMOLECULES, Apr. 2015, Peer-reviewed

  
• Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice

  Masaki Morishita; Yuki Takahashi; Makiya Nishikawa; Kohei Sano; Kana Kato; Takuma Yamashita; Takafumi Imai; Hideo Saji; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Feb. 2015, Peer-reviewed

  
• Nasal delivery of Japanese cedar pollen Cryj1 by using self-gelling immunostimulatory DNA for effective induction of immune responses in mice

  Yumiko Ishii-Mizuno; Yuka Umeki; Yuki Takahashi; Yukinori Kato; Tetsuji Takabayashi; Shigeharu Fujieda; Yoshinobu Takakura; Makiya Nishikawa

  JOURNAL OF CONTROLLED RELEASE, Feb. 2015, Peer-reviewed

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• Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice.

  Takafumi Imai; Yuki Takahashi; Makiya Nishikawa; Kana Kato; Masaki Morishita; Takuma Yamashita; Akihiro Matsumoto; Chonlada Charoenviriyakul; Yoshinobu Takakura

  Journal of extracellular vesicles, 2015, Peer-reviewed

  
• Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice.

  Takafumi Imai; Yuki Takahashi; Makiya Nishikawa; Kana Kato; Masaki Morishita; Takuma Yamashita; Akihiro Matsumoto; Chonlada Charoenviriyakul; Yoshinobu Takakura

  Journal of extracellular vesicles, 2015, Peer-reviewed

  
• Effects of upregulated indoleamine 2, 3-dioxygenase 1 by interferon gamma gene transfer on interferon gamma-mediated antitumor activity

  K. W Watcharanurak; L. Zang; M. Nishikawa; K. Yoshinaga; Y. Yamamoto; Y. Takahashi; M. Ando; K. Saito; Y. Watanabe; Y. Takakura

  GENE THERAPY, Sep. 2014, Peer-reviewed

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• Streptavidin-biotin結合に基づいたexosome放射標識法によるexosome体内動態の定量的解析

  森下 将輝; 高橋 有己; 佐野 紘平; 西川 元也; 佐治 英郎; 高倉 喜信

  日本DDS学会学術集会プログラム予稿集, Jul. 2014

  
• DNA nanotechnology-based development of delivery systems for bioactive compounds

  Kohta Mohri; Makiya Nishikawa; Yuki Takahashi; Yoshinobu Takakura

  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Jul. 2014, Peer-reviewed

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• Efficient delivery of immunostimulatory DNA to mouse and human immune cells through the construction of polypod-like structured DNA

  Shota Uno; Makiya Nishikawa; Kohta Mohri; Yuka Umeki; Noriyuki Matsuzaki; Yuki Takahashi; Haruyuki Fujita; Norimitsu Kadowaki; Yoshinobu Takakura

  NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, May 2014, Peer-reviewed

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• Enhancement of Anticancer Effect of Interferon-gamma Gene Transfer against Interferon-gamma-Resistant Tumor by Depletion of Tumor-Associated Macrophages

  Tsuyoshi Kiyota; Yuki Takahashi; Kanitta Watcharanurak; Makiya Nishikawa; Saori Ohara; Mitsuru Ando; Yoshihiko Watanabe; Yoshinobu Takakura

  MOLECULAR PHARMACEUTICS, May 2014, Peer-reviewed

  
• Injectable, self-gelling, biodegradable, and immunomodulatory DNA hydrogel for antigen delivery

  Makiya Nishikawa; Kohei Ogawa; Yuka Umeki; Kohta Mohri; Yohji Kawasaki; Hiroshi Watanabe; Natsuki Takahashi; Eri Kusuki; Rei Takahashi; Yuki Takahashi; Yoshinobu Takakura

  JOURNAL OF CONTROLLED RELEASE, Apr. 2014, Peer-reviewed

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• Streptavidin-biotin結合を利用したexosomeの放射標識によるexosome体内動態定量的解析法の開発

  森下 将輝; 高橋 有己; 佐野 紘平; 西川 元也; 佐治 英郎; 高倉 喜信

  日本薬学会年会要旨集, Mar. 2014

  
• Long-Term Elimination of Hepatitis C Virus from Human Hepatocyte Chimeric Mice After Interferon-gamma Gene Transfer

  Yuki Takahashi; Mitsuru Ando; Makiya Nishikawa; Nobuhiko Hiraga; Michio Imamura; Kazuaki Chayama; Yoshinobu Takakura

  HUMAN GENE THERAPY CLINICAL DEVELOPMENT, Mar. 2014, Peer-reviewed

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• Long-term elimination of hepatitis C virus from human hepatocyte chimeric mice after interferon-γ Gene Transfer

  Yuki Takahashi; Mitsuru Ando; Makiya Nishikawa; Nobuhiko Hiraga; Michio Imamura; Kazuaki Chayama; Yoshinobu Takakura

  Human Gene Therapy Clinical Development, 01 Mar. 2014, Peer-reviewed

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• Removal of transgene-expressing cells by a specific immune response induced by sustained transgene expression

  Yalei Yin; Yuki Takahashi; Norifumi Ebisuura; Makiya Nishikawa; Yoshinobu Takakura

  JOURNAL OF GENE MEDICINE, Mar. 2014, Peer-reviewed

  
• Transplantation of insulin-secreting multicellular spheroids for the treatment of type 1 diabetes in mice

  Kosuke Kusamori; Makiya Nishikawa; Narumi Mizuno; Tomoko Nishikawa; Akira Masuzawa; Kazunori Shimizu; Satoshi Konishi; Yuki Takahashi; Yoshinobu Takakura

  JOURNAL OF CONTROLLED RELEASE, Jan. 2014, Peer-reviewed

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• Prevention of adverse events of interferon gamma gene therapy by gene delivery of interferon gamma-heparin-binding domain fusion protein in mice

  Mitsuru Ando; Yuki Takahashi; Takuma Yamashita; Mai Fujimoto; Makiya Nishikawa; Yoshihiko Watanabe; Yoshinobu Takakura

  MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2014, Peer-reviewed

  
• Expression Profile-Dependent Improvement of Insulin Sensitivity by Gene Delivery of Interleukin-6 in a Mouse Model of Type II Diabetes

  Hanae Mukumoto; Yuki Takahashi; Mitsuru Ando; Makiya Nishikawa; Yoshinobu Takakura

  MOLECULAR PHARMACEUTICS, Oct. 2013, Peer-reviewed

  
• Gene Delivery of Albumin Binding Peptide-Interferon-gamma Fusion Protein with Improved Pharmacokinetic Properties and Sustained Biological Activity

  Noriko Miyakawa; Makiya Nishikawa; Yuki Takahashi; Mitsuru Ando; Masayuki Misaka; Yoshihiko Watanabe; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Sep. 2013, Peer-reviewed

  
• Poly(N-isopropylacrylamide)-coated microwell arrays for construction and recovery of multicellular spheroids

  Kazunori Shimizu; Kosuke Kusamori; Makiya Nishikawa; Narumi Mizuno; Tomoko Nishikawa; Akira Masuzawa; Shingo Katano; Yuki Takahashi; Yoshinobu Takakura; Satoshi Konishi

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Jun. 2013, Peer-reviewed

  
• Regulation of immunological balance by sustained interferon-γ gene transfer for acute phase of atopic dermatitis in mice

  K. Watcharanurak; M. Nishikawa; Y. Takahashi; K. Kabashima; R. Takahashi; Y. Takakura

  Gene Therapy, May 2013, Peer-reviewed

  
• Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection

  Yuki Takahashi; Makiya Nishikawa; Haruka Shinotsuka; Yuriko Matsui; Saori Ohara; Takafumi Imai; Yoshinobu Takakura

  JOURNAL OF BIOTECHNOLOGY, May 2013, Peer-reviewed

  
• Controlling the kinetics of interferon transgene expression for improved gene therapy

  Kanitta Watcharanurak; Makiya Nishikawa; Yuki Takahashi; Yoshinobu Takakura

  JOURNAL OF DRUG TARGETING, Nov. 2012, Peer-reviewed

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• Increased immunostimulatory activity of polypod-like structured DNA by ligation of the terminal loop structures

  Kohta Mohri; Natsuki Takahashi; Makiya Nishikawa; Eri Kusuki; Tomoki Shiomi; Yuki Takahashi; Yoshinobu Takakura

  JOURNAL OF CONTROLLED RELEASE, Nov. 2012, Peer-reviewed

  
• Fibronectin inhibits cytokine production induced by CpG DNA in macrophages without direct binding to DNA

  Hiroyuki Yoshida; Makiya Nishikawa; Sachiyo Yasuda; Hiroyasu Toyota; Tsuyoshi Kiyota; Yuki Takahashi; Yoshinobu Takakura

  CYTOKINE, Oct. 2012, Peer-reviewed

  
• Design and Development of Nanosized DNA Assemblies in Polypod-like Structures as Efficient Vehicles for Immunostimulatory CpG Motifs to Immune Cells

  Kohta Mohri; Makiya Nishikawa; Natsuki Takahashi; Tomoki Shiomi; Nao Matsuoka; Kohei Ogawa; Masayuki Endo; Kumi Hidaka; Hiroshi Sugiyama; Yuki Takahashi; Yoshinobu Takakura

  ACS NANO, Jul. 2012, Peer-reviewed

  
• Near-Infrared Fluorescence Probes for Enzymes Based on Binding Affinity Modulation of Squarylium Dye Scaffold

  Daihi Oushiki; Hirotatsu Kojima; Yuki Takahashi; Toru Komatsu; Takuya Terai; Kenjiro Hanaoka; Makiya Nishikawa; Yoshinobu Takakura; Tetsuo Nagano

  ANALYTICAL CHEMISTRY, May 2012, Peer-reviewed

  
• Constant and steady transgene expression of interferon-gamma by optimization of plasmid construct for safe and effective interferon-gamma gene therapy

  Mitsuru Ando; Yuki Takahashi; Makiya Nishikawa; Yoshihiko Watanabe; Yoshinobu Takakura

  JOURNAL OF GENE MEDICINE, Apr. 2012, Peer-reviewed

  
• Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice

  Xin Guan; Makiya Nishikawa; Hisoon Li; Takahashi Rei; Yuki Takahashi; Yoshinobu Takakura

  HUMAN VACCINES & IMMUNOTHERAPEUTICS, Feb. 2012, Peer-reviewed

  
• Comparison of antigen expression from plasmid DNA in tumor-free and antigen-expressing tumor-bearing mice

  Xin Guan; Makiya Nishikawa; Hisoon Li; Rei Takahashi; Yuki Takahashi; Yoshinobu Takakura

  Human Vaccines and Immunotherapeutics, Feb. 2012, Peer-reviewed

  
• Development of safe and effective nonviral gene therapy by eliminating CpG motifs from plasmid DNA vector

  Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  Frontiers in Bioscience - Scholar, 01 Jan. 2012, Peer-reviewed

  
• Saturation of Transgene Protein Synthesis From mRNA in Cells Producing a Large Number of Transgene mRNA

  Yuki Takahashi; Makiya Nishikawa; Naomi Takiguchi; Tetsuya Suehara; Yoshinobu Takakura

  BIOTECHNOLOGY AND BIOENGINEERING, Oct. 2011, Peer-reviewed

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• Inhibition of nuclear delivery of plasmid DNA and transcription by interferon gamma: hurdles to be overcome for sustained gene therapy

  L. Zang; M. Nishikawa; K. Machida; M. Ando; Y. Takahashi; Y. Watanabe; Y. Takakura

  GENE THERAPY, Sep. 2011, Peer-reviewed

  
• Inhibition of surgical trauma-enhanced peritoneal dissemination of tumor cells by human catalase derivatives in mice

  Chika Nishizaki; Makiya Nishikawa; Tomoya Yata; Toshiyuki Yamada; Yuki Takahashi; Masahide Oku; Hiroya Yurimoto; Yasuyoshi Sakai; Kenji Nakanishi; Yoshinobu Takakura

  FREE RADICAL BIOLOGY AND MEDICINE, Aug. 2011, Peer-reviewed

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• Prolonged Circulation Half-life of Interferon gamma Activity by Gene Delivery of Interferon gamma-Serum Albumin Fusion Protein in Mice

  Noriko Miyakawa; Makiya Nishikawa; Yuki Takahashi; Mitsuru Ando; Masayuki Misaka; Yoshihiko Watanabe; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Jun. 2011, Peer-reviewed

  
• Positive Correlation Between the Generation of Reactive Oxygen Species and Activation/Reactivation of Transgene Expression After Hydrodynamic Injections into Mice

  Naomi Takiguchi; Yuki Takahashi; Makiya Nishikawa; Yuriko Matsui; Yasushi Fukuhara; Daihi Oushiki; Kazuki Kiyose; Kenjiro Hanaoka; Tetsuo Nagano; Yoshinobu Takakura

  PHARMACEUTICAL RESEARCH, Apr. 2011, Peer-reviewed

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• 5′-Phosphate oligodeoxynucleotides enhance the phosphodiester-CpG DNA-induced inflammatory response in macrophages

  Hiroyuki Yoshida; Makiya Nishikawa; Tsuyoshi Kiyota; Shota Uno; Hiroyasu Toyota; Rei Takahashi; Miwako Narita; Yoshinobu Takakura

  European Journal of Immunology, Feb. 2011, Peer-reviewed

  
• Biodegradable CpG DNA hydrogels for sustained delivery of doxorubicin and immunostimulatory signals in tumor-bearing mice

  Makiya Nishikawa; Yumiko Mizuno; Kohta Mohri; Nao Matsuoka; Sakulrat Rattanakiat; Yuki Takahashi; Hisakage Funabashi; Dan Luo; Yoshinobu Takakura

  BIOMATERIALS, Jan. 2011, Peer-reviewed

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• Optimization of Gene Therapy Effect by Spaciotemporal Control of Expressed Proteins

  Makiya Nishikawa; Yuki Takahashi; Yoshinobu Takakura

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Nov. 2010, Peer-reviewed

  
• Persistent interferon transgene expression by RNA interference-mediated silencing of interferon receptors

  Yuki Takahashi; Elin Vikman; Makiya Nishikawa; Mitsuru Ando; Yoshihiko Watanabe; Yoshinobu Takakura

  JOURNAL OF GENE MEDICINE, Sep. 2010, Peer-reviewed

  
• Sustained Exogenous Expression of Therapeutic in Levels of IFN-gamma Ameliorates Atopic Dermatitis in NC/Nga Mice via Th1 Polarization

  Kayoko Hattori; Makiya Nishikawa; Kanitta Watcharanurak; Akihiko Ikoma; Kenji Kabashima; Hiroyasu Toyota; Yuki Takahashi; Rei Takahashi; Yoshihiko Watanabe; Yoshinobu Takakura

  JOURNAL OF IMMUNOLOGY, Mar. 2010, Peer-reviewed

  
• Induction of Tumor-specific Immune Response by Gene Transfer of Hsp70-cell-penetrating Peptide Fusion Protein to Tumors in Mice

  Makiya Nishikawa; Takayuki Otsuki; Atsushi Ota; Xin Guan; Seiji Takemoto; Yuki Takahashi; Yoshinobu Takakura

  MOLECULAR THERAPY, Feb. 2010, Peer-reviewed

  
• The Aldo-Keto Reductase Akr1b7 Gene Is a Common Transcriptional Target of Xenobiotic Receptors Pregnane X Receptor and Constitutive Androstane Receptor

  Ming-Jie Liu; Yuki Takahashi; Taira Wada; Jinhan He; Jie Gao; Yanan Tian; Song Li; Wen Xie

  MOLECULAR PHARMACOLOGY, Sep. 2009, Peer-reviewed

  
• TLR9-dependent systemic interferon-beta production by intravenous injection of plasmid DNA/cationic liposome complex in mice

  Hiroyuki Yoshida; Makiya Nishikawa; Sachiyo Yasuda; Yumiko Mizuno; Hiroyasu Toyota; Tsuyoshi Kiyota; Rei Takahashi; Yoshinobu Takakura

  JOURNAL OF GENE MEDICINE, Aug. 2009, Peer-reviewed

  
• Nonviral vector-mediated RNA interference: Its gene silencing characteristics and important factors to achieve RNAi-based gene therapy

  Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  ADVANCED DRUG DELIVERY REVIEWS, Jul. 2009, Peer-reviewed

  
• Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression

  Masaru Mitsui; Makiya Nishikawa; Lei Zang; Mitsuru Ando; Kayoko Hattori; Yuki Takahashi; Yoshihiko Watanabe; Yoshinobu Takakura

  JOURNAL OF GENE MEDICINE, May 2009, Peer-reviewed

  
• Quantitative and Temporal Analysis of Gene Silencing in Tumor Cells Induced by Small Interfering RNA or Short Hairpin RNA Expressed from Plasmid Vectors

  Yuki Takahashi; Kiyoshi Yamaoka; Makiya Nishikawa; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Jan. 2009, Peer-reviewed

  
• The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor. jointly worked

  Liu MJ; Takahashi Y; Wada T; He J; Gao J; Tian Y; Li S; Xie W

  Molecular Pharmacology,vol. 76, pp. 604-611, 2009, Peer-reviewed

  
• The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor

  Liu Ming-Jie; Takahashi Yuki; Wada Taira; He Jinhan; Gao Jie; Tian Yanan; Li Song; Xie Wen

  Molecular pharmacology, 2009, Peer-reviewed

  
• Gene silencing of beta-catenin in melanoma cells retards their growth but promotes the formation of pulmonary metastasis in mice

  Yuki Takahashi; Makiya Nishikawa; Tetsuya Suehara; Naomi Takiguchi; Yoshinobu Takakura

  INTERNATIONAL JOURNAL OF CANCER, Nov. 2008, Peer-reviewed

  
• Reactivation of Silenced Transgene Expression in Mouse Liver by Rapid, Large-Volume Injection of Isotonic Solution

  Makiya Nishikawa; Ayumi Nakayama; Yuki Takahashi; Yasushi Fukuhara; Yoshinobu Takakura

  HUMAN GENE THERAPY, Oct. 2008, Peer-reviewed

  
• Enhancement of antiproliferative activity of interferons by RNA interference-mediated silencing of SOCS gene expression in tumor cells

  Yuki Takahashi; Haruka Kaneda; Nana Takasuka; Kayoko Hattori; Makiya Nishikawa; Yoshinobu Takakura

  CANCER SCIENCE, Aug. 2008, Peer-reviewed

  
• Inhibition of tumor cell growth in the liver by RNA interference-mediated suppression of HIF-1 alpha expression in tumor cells and hepatocytes

  Y. Takahashi; M. Nishikawa; Y. Takakura

  GENE THERAPY, Apr. 2008, Peer-reviewed

  
• Three-dimensional seismic isolator with tilt prevention mechanism

  Matsuhisa H; Takahashi Y; Utsuno H; Yamada K; Yasuda M

  15th International Congress on Sound and Vibration 2008, ICSV 2008, 2008, Peer-reviewed

  
• Design of PCR-amplified DNA fragments for in vivo gene delivery: Size-dependency on stability and transgene expression

  Kazuhiro Hirata; Makiya Nishikawa; Naoki Kobayashi; Yuki Takahashi; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Sep. 2007, Peer-reviewed

  
• Improved anti-cancer effect of interferon gene transfer by sustained expression using CpG-reduced plasmid DNA

  Hiroki Kawano; Makiya Nishikawa; Masaru Mitsui; Yuki Takahashi; Keiko Kako; Kiyoshi Yamaoka; Yoshihiko Watanabe; Yoshinobu Takakura

  INTERNATIONAL JOURNAL OF CANCER, Jul. 2007, Peer-reviewed

  
• Novel material and strategy for gene delivery

  Hiroto Hatakeyama; Yuki Takahashi

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2007, Peer-reviewed

  
• Suppression of tumor growth by intratumoral injection of short hairpin RNA-expressing plasmid DNA targeting beta-catenin or hypoxia-inducible factor 1 alpha

  Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  JOURNAL OF CONTROLLED RELEASE, Nov. 2006, Peer-reviewed

  
• Moment analysis for kinetics of gene silencing by RNA interference

  Y Takahashi; K Yamaoka; M Nishikawa; Y Takakura

  BIOTECHNOLOGY AND BIOENGINEERING, Mar. 2006, Peer-reviewed

  
• Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: Quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases

  Y Takahashi; M Nishikawa; N Kobayashi; Y Takakura

  JOURNAL OF CONTROLLED RELEASE, Jul. 2005, Peer-reviewed

  
• Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice

  M Nishikawa; A Tamada; K Hyoudou; Y Umeyama; Y Takahashi; Y Kobayashi; H Kumai; E Ishida; F Staud; Y Yabe; Y Takakura; F Yamashita; M Hashida

  CLINICAL & EXPERIMENTAL METASTASIS, 2004, Peer-reviewed

  

Misc.

• Possibility of exosomes as drug delivery system

  高橋 有己; 高倉 喜信

  細胞, Jan. 2016

  
• Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion (vol 5, 14979, 2015)

  Tomoya Yata; Yuki Takahashi; Mengmeng Tan; Kumi Hidaka; Hiroshi Sugiyama; Masayuki Endo; Yoshinobu Takakura; Makiya Nishikawa

  SCIENTIFIC REPORTS, Jan. 2016

  
• DDS を指向した exosome 体内動態の解析と制御

  高橋有己; 西川元也; 高倉喜信

  YAKUGAKU ZASSHI, 2016, Peer-reviewed

  
• 核酸医薬のための次世代DDS開発

  西川元也; 高橋有己; 高倉喜信

  PHARM TECH JAPAN, Jan. 2015

  
• クローズアップ実験法 ハイドロダイナミクス法－高効率なin vivo遺伝子導入法

  高橋有己; 西川元也; 高倉喜信

  実験医学, Jan. 2015

  
• エクソソームの体内動態

  高橋有己; 西川元也; 高倉喜信

  Drug Delivery System, 2014, Peer-reviewed

  
• Exosome の特性と exosome を利用した診断・治療法の開発 (特集 脂質から形成されるナノマテリアル)

  森下将輝; 高橋有己; 西川元也

  オレオサイエンス, 2014, Peer-reviewed

  
• バイオ医薬品の動態制御

  高橋有己; 西川元也; 高倉喜信

  薬剤学, 2014, Peer-reviewed

  
• 細胞スフェロイド化技術の開発と細胞治療への応用

  草森浩輔; 西川元也; 高橋有己; 高倉喜信

  Drug Delivery System, 2013, Peer-reviewed

  
• RNA 干渉の適用による疾患治療法の開発

  高橋有己

  薬剤学= The archives of practical pharmacy, 2013, Peer-reviewed

  
• Control of Spatiotemporal Distribution of Interferon gamma by Genetically Fusing Functional Peptides

  Mitsuru Ando; Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Dec. 2012, Peer-reviewed

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• Development of Target-specific Gene Therapy System by Controlling Distribution of Interferon

  Yuki Takahashi

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Sep. 2012, Peer-reviewed

  
• 機能性ペプチド融合によるInterferon ?時空間制御

  安藤満; 高橋有己; 西川元也; 高倉喜信

  YAKUGAKU ZASSHI, Jan. 2012

  
• 核酸ナノデバイスの開発とDDS応用

  西川元也; 毛利浩太; 高橋有己; 高倉喜信

  遺伝子医学MOOK20号「ナノバイオ技術と最新創薬応用研究」, Jan. 2012

  
• RNA 干渉を利用した疾患治療システム

  高橋有己; Takahashi Yuki; 西川元也; Nishikawa Makiya; 高倉喜信; Takakura Yoshinobu

  生体の科学, 2012, Peer-reviewed

  
• RNA 干渉を利用した疾患治療システムの開発

  高橋有己

  Drug delivery system, 2010, Peer-reviewed

  
• 発現タンパク質の時空間制御による遺伝子治療効果の最適化

  西川元也; 高橋有己; 高倉喜信

  YAKUGAKU ZASSHI, 2010, Peer-reviewed

  
• Development of oligonucleotide-based nano-sized DDS

  Kohta Mohri; Makiya Nishikawa; Yuki Takahaski; Yoshinobu Takakura

  Drug Delivery System, 2010, Peer-reviewed

  
• In vivo siRNA delivery to tumor cells and its application to cancer gene therapy

  Yuki Takahashi; Makiya Nishikawa; Yoshinobu Takakura

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2007, Peer-reviewed

  
• Delivery of vectors expressing short hairpin RNA for cancer therapy

  Makiya Nishikawa; Yuki Takahashi; Yoshinobu Takakura

  Drug Delivery System, 2007, Peer-reviewed

  
• 新たな素材・戦略を用いた遺伝子デリバリー

  畠山浩人; 高橋有己

  YAKUGAKU ZASSHI, 2007, Peer-reviewed

  
• がん細胞への siRNA デリバリーとがん遺伝子治療への適用

  高橋有己; 西川元也; 高倉喜信

  薬学雑誌. 乙号, 2007, Peer-reviewed

  
• プラスミドベクターおよび投与方法の最適化によるインターフェロン遺伝子治療効果の増強

  町田一哉; 西川元也; 光井優; 高橋有己; 高倉喜信

  薬剤学= Journal of Pharmaceutical Science and Technology, Japan, 2007, Peer-reviewed

  
• Hydrodynamics法を用いたRNAiベクターの導入法

  高橋有己; 西川元也; 高倉喜信

  改訂RNAi実験プロトコール, Jan. 2004

  

Presentations

• 細胞外小胞の動態解析に基づく疾患治療法の開発

  髙橋 有己

  第6回日本細胞外小胞学会, Oct. 2019

  
• Pharmacokinetics of Exosomes Evaluated by Using Exosome Labeling Methods

  髙橋 有己

  大阪府立大学 研究推進機構 第31 回ケミカルバイオロジー研究所セミナー, Apr. 2019

  
• ３次元構造化による免疫細胞への核酸デリバリー

  髙橋 有己; 西川元也; 高倉喜信

  第34回日本DDS学会, Jun. 2018

  
• 細胞外小胞エキソソームを基盤とした疾患治療法の開発

  髙橋 有己

  第11回次世代を担う若手医療薬科学シンポジウム, Oct. 2017, Invited

  
• 核酸医薬のDDSへの応用を目的とした体内動態制御型核酸搭載exosomeの開発

  髙橋 有己

  第31回日本DDS学会学術集会, Jul. 2015, Invited

  
• DDSを指向したexosome体内動態の解析と制御

  髙橋 有己

  日本薬学会第135年会, Mar. 2015, Invited

  
• Exosomeを基盤とするDDS開発を指向した体内動態評価システムの開発

  髙橋 有己

  第29回日本DDS学会学術集会, Jul. 2013, Invited

  
• 体内動態と生体応答の制御に基づくインターフェロン癌遺伝子治療法の開発

  髙橋 有己

  日本薬剤学会第30年会, May 2012, Invited

  
• 体内動態制御によるインターフェロン遺伝子治療の最適化

  髙橋 有己

  第26回日本DDS学会学術集会, Jun. 2010, Invited

  

Books and Other Publications

• Diagnostic and Therapeutic Applications of Exosomes in Cancer

  Takahashi Y; Takakura Y, Contributor, Exosomes in Cancer Immunotherapy.

  Elsevier, 2018, Not refereed

  
• Extracellular Vesicles

  Takahashi Y; Nishikawa M; Takakura Y, Contributor, In Vivo Tracking of Extracellular Vesicles in Mice Using Fusion Protein Comprising Lactadherin and Gaussia Luciferase.

  Wiley, 2017, Not refereed

  
• 核酸医薬のための次世代DDS開発

  髙橋 有己

  ファームテックジャパン, 2015, Not refereed

  
• バイオ医薬品の動態制御

  髙橋 有己

  薬剤学, 2014, Not refereed

  
• エクソソームの体内動態

  髙橋 有己

  Drug Delivery System, 2014, Not refereed

  
• 薬剤学実験法必携マニュアル―(分担執筆）

  髙橋 有己; 高倉 喜信, Contributor, 遺伝子製剤

  南江堂, 2014, Not refereed

  
• Exosomeの特性とexosomeを利用した診断・治療法の開発

  髙橋 有己

  オレオサイエンス, 2014, Not refereed

  
• RNA 干渉の適用による疾患治療法の開発

  髙橋 有己

  薬剤学, 2013, Not refereed

  
• 細胞スフェロイド化技術の開発と細胞治療への応用

  髙橋 有己

  Drug Delivery System, 2013, Not refereed

  
• RNA干渉を利用した疾患治療システム

  髙橋 有己

  生体の科学, 2012, Not refereed

  
• RNA干渉を利用した疾患治療システムの開発

  髙橋 有己

  Drug Delivery System, 2010, Not refereed

  
• オリゴ核酸を基盤とするナノサイズDDS開発

  髙橋 有己

  Drug Delivery System, 2010, Not refereed

  
• 改訂RNAi実験プロトコール（分担執筆）

  髙橋 有己, Contributor, Hydrodynamics法を用いたRNAiベクターの導入法

  羊土社, 2005, Not refereed

  

Industrial Property Rights

• 特開WO2012/144560, 自己ゲル化核酸

  西川元也; 高橋有己; 高倉喜信

  

Awards

• 31 May 2018

  日本薬剤学会, 日本薬剤学会奨励賞

External funds: Kakenhi

• Development of vaccines based on the maximization of immune function and control of pharmacokinetics of extracellular vesicles derived from dendritic cells

  Grant-in-Aid for Scientific Research (B)

  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related

  Kyoto University

  Yoshinobu Takakura

  From 01 Apr. 2021, To 31 Mar. 2024, Project Closed

  細胞外小胞;エクソソーム;樹状細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21H02616/
• Development of tissue-cell two-step targeting method using cells producing siRNA-loaded exosomes.

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 90:Biomedical engineering and related fields

  Kyoto University

  Yuki Takahashi

  From 30 Jul. 2020, To 31 Mar. 2022, Project Closed

  細胞外小胞;エキソソーム;エクソソーム

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K21891/
• Analysis of naturally stealth exosome and its application as drug delivery carrier

  Grant-in-Aid for Scientific Research (B)

  Basic Section 90120:Biomaterials-related

  Kyoto University

  Yuki Takahashi

  From 01 Apr. 2020, To 31 Mar. 2024, Project Closed

  細胞外小胞;エキソソーム;ホスファチジルセリン;血中滞留性

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H04533/
• Development of in vivo gene therapy using exosomes loading immunomodulatory molecules

  Grant-in-Aid for Scientific Research (B)

  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related

  Kyoto University

  Yoshinobu Takakura

  From 01 Apr. 2018, To 31 Mar. 2021, Project Closed

  エキソソーム;ルシフェラーゼ;免疫療法;サイトカイン;免疫;内因性

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18H02562/
• Exploration of extracellular vesicles with long blood retention time and evaluateion of its physiological function

  Grant-in-Aid for Challenging Research (Exploratory)

  Kyoto University

  Yuki Takahashi

  From 30 Jun. 2017, To 31 Mar. 2019, Project Closed

  細胞由来小胞;エキソソーム;ルシフェラーゼ;細胞外小胞;体内動態

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K19390/
• Development of cytokine gene therapy with high therapeutic index by systemic regulation of transgene expression and biological response.

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Yoshinobu Takakura

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  遺伝子治療;サイトカイン;プラスミドDNA;ドラッグデリバリー;インターフェロン;抗原特異的免疫応答

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H04638/
• Efficient induction of in vivo RNA interference by designing exosome-tropic siRNA derivatives

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Yuki Takahashi

  From 01 Apr. 2014, To 31 Mar. 2016, Project Closed

  エキソソーム;ラジオアイソトープ;DDS;SELEX法

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26670266/
• Development of DDS applicable for immune therapy by using self-assembling RNA sponge particle

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Yoshinobu Takakura

  From 01 Apr. 2014, To 31 Mar. 2016, Project Closed

  ドラッグデリバリー;アジュバント;ワクチン;TLR3

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26670013/
• Development of therapeutic systems based on three-dimensional DNA nanostructures

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Makiya Nishikawa

  From 01 Apr. 2014, To 31 Mar. 2017, Project Closed

  核酸;DNA;DDS;ハイドロゲル;抗原

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26293008/
• Development of interferon cancer gene therapy by optimizing structure/pharmacokinetics/activity of transgene product

  Grant-in-Aid for Young Scientists (A)

  Kyoto University

  Yuki Takahashi

  From 01 Apr. 2013, To 31 Mar. 2016, Project Closed

  インターフェロン;遺伝子治療;DDS;ルシフェラーゼ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25713003/
• Development of microtissue therapeutic system based on mixed multicellular spheroids

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Makiya NISHIKAWA

  From 01 Apr. 2013, To 31 Mar. 2015, Project Closed

  細胞治療;スフェロイド;幹細胞;移植

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25670257/
• Development of target-specific multifunctional exosomes loaded with RNA drugs

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Yuki TAKAHASHI

  From 01 Apr. 2012, To 31 Mar. 2014, Project Closed

  ドラッグデリバリー;エキソソーム;ルシフェラーゼ;イメージング;DDS

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24659260/
• Optimization of cytokine gene therapy based on the regulation of transcription/translation, pharmacokinetics, and cellular response.

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Yoshinobu TAKAKURA

  From 01 Apr. 2012, To 31 Mar. 2015, Project Closed

  ドラッグデリバリー;遺伝子治療;インターフェロン;IDO-1;腫瘍組織関連マクロファージ;抗原特異的免疫応答;サイトカイン;プラスミドDNA;融合タンパク質;RNA干渉

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24390008/
• Development of targeted cell therapeutic systems based on cell characteristics

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Makiya NISHIKAWA

  From 01 Apr. 2011, To 31 Mar. 2013, Project Closed

  ドラッグデリバリー;細胞治療;体内分布;イメージング;細胞個性;細胞スフェロイド;PEG修飾

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23659283/
• Development of nano-sized DDS for nucleic acid drugs based on polypod-like structured nucleic acids

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Makiya NISHIKAWA

  From 01 Apr. 2011, To 31 Mar. 2014, Project Closed

  核酸;ナノ粒子;DDS;CpG;siRNA

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23390010/
• Development of target-specific gene therapy system by using cell surface adhesive interferon.

  Grant-in-Aid for Young Scientists (B)

  Kyoto University

  Yuki TAKAHASHI

  From 01 Apr. 2010, To 31 Mar. 2012, Project Closed

  ドラッグデリバリー;遺伝子治療;インターフェロン;薬学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22790034/
• 一回の投与で繰り返しタンパク質を供給可能なオンデマンド型遺伝子治療システムの開発

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  高倉 喜信

  From 01 Apr. 2010, To 31 Mar. 2011, Project Closed

  遺伝子発現;肝臓;転写因子;非ウィルスベクター;物理刺激

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659009/
• 細胞外小胞を基盤とした抗原特異的免疫応答の精密制御技術の創製

  Grant-in-Aid for Scientific Research (B)

  Basic Section 90120:Biomaterials-related

  Kyoto University

  高橋 有己

  From 01 Apr. 2024, To 31 Mar. 2028, Granted

  細胞外小胞;ワクチン

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K03280/
• 自然免疫型T細胞の機能を利用した新たな創薬モダリティの創出

  Grant-in-Aid for Scientific Research (B)

  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related

  The University of Tokushima

  井貫 晋輔

  From 01 Apr. 2024, To 31 Mar. 2028, Granted

  自然免疫型T細胞;MAIT細胞;MR1リガンド;コンジュゲート化;構造活性相関;低分子リガンド;ワクチンアジュバント;がん治療モダリティ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K02147/

External funds: others

• Development of RNA interference transduction system by using cell penetrating peptide.

  武田科学振興財団　薬学系研究奨励

  From 2010, To 2010

  代表

Education

Teaching subject(s)

• From 01 Apr. 2025, To 31 Mar. 2026

  ILAS Seminar

  Z001, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Laboratory Practice in Pharmaceutical Sciences II

  6304, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2025, To 31 Mar. 2026

  Laboratory Practice in Pharmaceutical Sciences I

  6303, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2025, To 31 Mar. 2026

  Laboratory Practice in Basic Pharmacodynanic Sciences

  4208, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2025, To 31 Mar. 2026

  Pharmaceutics I (Galenical Pharmacy)

  C310, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Pharmaceutics 1 (Liquid Formulations)

  A310, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  ２１ＣＯＥ化学講義３（理）

  8001, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Seminar for Pharmaceutical Sciences III

  6106, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Seminar for Pharmaceutical Sciences II

  6105, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Seminar for Pharmaceutical Sciences I

  6104, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences

  1208, Fall, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Basic Laboratory Techniques in Pharmaceutical Sciences

  6003, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Seminar in Basic Patho-Functional Analysis

  2308, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences

  1208, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Research in Pharmaceutical Sciences II

  6202, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2025, To 31 Mar. 2026

  Research in Pharmaceutical Sciences I

  6201, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2025, To 31 Mar. 2026

  Research in Basic Pharmacodynanic Sciences

  3208, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2025, To 31 Mar. 2026

  Research in Pharmaceutical Sciences III

  6203, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2025, To 31 Mar. 2026

  Pharmaceutical Laboratory III : Pharmaceutics and Pharmacology

  C905, Fall, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Practice in Pharmaceutical Sciences I

  6303, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Practice in Basic Pharmacodynanic Sciences

  4208, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Practice in Pharmaceutical Sciences II

  6304, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutics I (Galenical Pharmacy)

  C310, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutics 1 (Liquid Formulations)

  A310, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Research in Pharmaceutical Sciences I

  6201, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Research in Basic Pharmacodynanic Sciences

  3208, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Research in Pharmaceutical Sciences II

  6202, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory III : Pharmaceutics and Pharmacology

  C905, Fall, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar for Pharmaceutical Sciences II

  6105, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar for Pharmaceutical Sciences I

  6104, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Basic Laboratory Techniques in Pharmaceutical Sciences

  6003, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  ２１ＣＯＥ化学講義３（理）

  8001, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar for Pharmaceutical Sciences III

  6106, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar in Basic Patho-Functional Analysis

  2308, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences

  1208, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences

  1208, Fall, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Research in Pharmaceutical Sciences III

  6203, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Practice in Pharmaceutical Sciences II

  6304, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Practice in Pharmaceutical Sciences I

  6303, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Practice in Basic Pharmacodynanic Sciences

  4208, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory III : Pharmaceutics and Pharmacology

  C905, Fall, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  A905, Fall, Faculty of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Research in Pharmaceutical Sciences III

  6203, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Research in Pharmaceutical Sciences II

  6202, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Research in Pharmaceutical Sciences I

  6201, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Research in Basic Pharmacodynanic Sciences

  3208, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences

  1208, Fall, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  ２１ＣＯＥ化学講義３（理）

  8001, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Basic Laboratory Techniques in Pharmaceutical Sciences

  6003, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar in Basic Patho-Functional Analysis

  2308, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences

  1208, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar for Pharmaceutical Sciences III

  6106, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar for Pharmaceutical Sciences II

  6105, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar for Pharmaceutical Sciences I

  6104, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutics I (Galenical Pharmacy)

  C310, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutics 1 (Liquid Formulations)

  A310, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  A905, Fall, Faculty of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences

  1208, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar in Basic Patho-Functional Analysis

  2308, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Research in Basic Pharmacodynanic Sciences

  3208, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Basic Laboratory Techniques in Pharmaceutical Sciences

  6003, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutics 1 (Liquid Formulations)

  A310, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory III : Pharmaceutics and Pharmacology

  C905, Fall, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2022, To 31 Mar. 2023

  Laboratory Practice in Pharmaceutical Sciences I

  6303, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Laboratory Practice in Basic Pharmacodynanic Sciences

  4208, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  ２１ＣＯＥ化学講義３（理）

  8001, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Research in Pharmaceutical Sciences II

  6202, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Laboratory Practice in Pharmaceutical Sciences II

  6304, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar for Pharmaceutical Sciences I

  6104, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar for Pharmaceutical Sciences III

  6106, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar for Pharmaceutical Sciences II

  6105, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutics I (Galenical Pharmacy)

  C310, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Research in Pharmaceutical Sciences I

  6201, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Research in Pharmaceutical Sciences III

  6203, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From Apr. 2011, To Mar. 2012

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Research in Biopharmaceutics and Drug Metabolism

  Year-long, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Biopharmaceutics and Drug Metabolism Seminar

  Year-long, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Advanced Methods in Pharmacodynamic Sciences

  Year-long, 薬学研究科
• From Apr. 2011, To Mar. 2012

  薬学専門実習IV

  Fall, 薬学部
• From Apr. 2011, To Mar. 2012

  薬学専門実習３

  Fall, 薬学部
• From Apr. 2012, To Mar. 2013

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Pharmaceutical Laboratory III: Biochemistry and Microbiology

  Fall, 薬学部
• From Apr. 2012, To Mar. 2013

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2012, To Mar. 2013

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2013, To Mar. 2014

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2014, To Mar. 2015

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2015, To Mar. 2016

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2016, To Mar. 2017

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Fundamental Chemical Experiments

  Spring, 全学共通科目
• From Apr. 2017, To Mar. 2018

  Pharmaceutics 2 (Solid formulations)

  Spring, 薬学部
• From Apr. 2017, To Mar. 2018

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2017, To Mar. 2018

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2017, To Mar. 2018

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Pharmaceutics 2 (Solid formulations)

  Spring, 薬学部
• From Apr. 2018, To Mar. 2019

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2018, To Mar. 2019

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2018, To Mar. 2019

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  ILAS Seminar

  Spring, 全学共通科目
• From Apr. 2019, To Mar. 2020

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Pharmaceutics I (Galenical Pharmacy)

  Fall, 薬学部
• From Apr. 2019, To Mar. 2020

  Pharmaceutics 2 (Solid formulations)

  Spring, 薬学部
• From Apr. 2019, To Mar. 2020

  Pharmaceutics 1 (Liquid Formulations)

  Fall, 薬学部
• From Apr. 2019, To Mar. 2020

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2019, To Mar. 2020

  Laboratory Practice in Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Research in Pharmaceutical Sciences III

  Fall, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Research in Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Seminar for Pharmaceutical Sciences III

  Fall, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Seminar for Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Pharmaceutics I (Galenical Pharmacy)

  Fall, 薬学部
• From Apr. 2020, To Mar. 2021

  Pharmaceutics 1 (Liquid Formulations)

  Fall, 薬学部
• From Apr. 2020, To Mar. 2021

  Pharmaceutical Laboratory III : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2020, To Mar. 2021

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2020, To Mar. 2021

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Laboratory Practice in Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Research in Pharmaceutical Sciences III

  Spring, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Research in Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Seminar for Pharmaceutical Sciences III

  Spring, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Seminar for Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences

  Spring, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Basic Laboratory Techniques in Pharmacy and Biomedicinal Sciences

  Fall, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Pharmaceutics I (Galenical Pharmacy)

  Fall, 薬学部
• From Apr. 2021, To Mar. 2022

  Pharmaceutics 1 (Liquid Formulations)

  Fall, 薬学部
• From Apr. 2021, To Mar. 2022

  Basic Laboratory Techniques in Pharmaceutical Sciences

  Spring, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Basic Laboratory Techniques in Pharmaceutical Sciences

  Spring, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Pharmaceutical Laboratory III : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2021, To Mar. 2022

  Pharmaceutical Laboratory 3 : Pharmaceutics and Pharmacology

  Fall, 薬学部
• From Apr. 2021, To Mar. 2022

  Laboratory Practice in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Laboratory Practice in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科

Administration

School management (title, position)

• From 01 Oct. 2024, To 30 Sep. 2026

  動物実験委員会 委員
• From 01 Jun. 2024, To 31 Mar. 2026

  国際高等教育院 企画評価専門委員会 人文・社会科学部会1
• From 01 Apr. 2024, To 31 Mar. 2027

  環境科学センター　無機廃液管理小委員会　委員
• From 01 Jun. 2024, To 31 Mar. 2026

  国際高等教育院 企画評価専門委員会 人文・社会科学部会1
• From 01 Feb. 2018, To 31 Mar. 2020

  吉田事業場衛生委員会委員
• From 01 Aug. 2018, To 31 Mar. 2019

  物質―連携システム拠点連携助教
• From 01 Oct. 2018, To 30 Sep. 2020

  京都大学動物実験委員会 委員
• From 01 Oct. 2020, To 30 Sep. 2022

  京都大学動物実験委員会 委員

Faculty management (title, position)

• From 01 Apr. 2024, To 31 Mar. 2025

  実験動物施設運営委員会　委員
• From 01 Apr. 2012, To 31 Mar. 2025

  ホームページ広報委員会　委員
• From 01 Apr. 2014, To 31 Mar. 2025

  環境・安全衛生委員会　委員
• From 01 Apr. 2014

  衛生管理者
• From 01 Apr. 2011, To 31 Mar. 2016

  情報システム委員会　委員
• ＲＩ管理委員会　委員
• From 01 Apr. 2017, To 31 Mar. 2025

  建物・設備・共通機器管理運営委員会　委員
• From 01 May 2017, To 31 Mar. 2021

  薬学部構内実験排水系管理委員会 委員
• From 01 Apr. 2018, To 31 Mar. 2025

  教務委員会　委員
• From 01 Apr. 2018, To 31 Mar. 2025

  図書委員会　委員
• From 01 Apr. 2017, To 31 Mar. 2025

  動物実験委員会　委員