Basic Information

Affiliated programs (koza)

• Graduate School of Medicine, 医科学専攻 がん・幹細胞シグナル, 教授
• Graduate School of Medicine, 医学専攻 がん・幹細胞シグナル, 教授
• Graduate School of Pharmaceutical Sciences, 薬科学専攻 がん・幹細胞シグナル学, 教授

Professional Memberships

• International Society for Stem Cell Research
• Japanese Biochemistry Society
• The Molecular Biology Society of Japan
• The Japanese Society of Hematology
• International Society for Experimental Hematology
• Japanese Cancer Association

Academic Degree

• M.Sc.(The University of Tokyo)
• Ph.D.(The University of Tokyo)

Research History

• From 2022, To Present

  Kyoto University, Institute for Life and Medical Sciences, 教授, Professor
• From 2019, To 2022

  Kyoto University, Institute for Frontier Life and Medical Sciences, 教授
• From 2019, To 2019

  University of Georgia, Dept of Biochemistry and Molecular Biology, Associate Professor
• From 2013, To 2019

  University of Georgia, Dept of Biochemistry and Molecular Biology, Assistant Professor
• From 2011, To 2013

  University of California San Diego, Dept of Pharmacology, CIRM Postdoctoral fellow
• From 2007, To 2010

  Duke University Medical Center, Pharmacology and Cancer Biology, Postdoctoral fellow
• From 2000, To 2007

  The University of Tokyo, Graduate School of Pharmaceutical Sciences, Assistant Professor
• From 1998, To 2000

  Japan Society for the Promotion of Science (JSPS), JSPS Predoctoral Fellow

Language of Instruction

• English

researchmap URL

• https://researchmap.jp/takahiroito

Research

Research Topics, Overview of the research

• Research Topics

  Regulation of cell fates in stem cells and cancer

• Overview of the research

  What determines how stem cells and cancer behave?
  The primary goal of our research is to understand the molecular basis of self-renewal and differentiation in stem cells and cancer, i.e. cell fates. Specifically, we study hematopoiesis and myogenesis to identify cellular machinery that regulates tissue homeostasis and regeneration as well as molecular drivers of transformation that lead to human malignancies such as leukemia. We are particularly interested in the stem cell regulatory circuits governed by RNA binding proteins and cellular metabolism. Recent studies, including our own work, have revealed that normal stem cells and cancer share similar cellular hierarchy and regulatory signals while several components are distinct in these tissues. These results showed us that understanding machineries operating in stem cells and cancer could help us to develop new effective approaches to treat human diseases including cancers.

Research Interests

• metabolism
• stem cells
• cancer
• regulation of gene expression
• hematopoiesis

Research Areas

• Life sciences, Tumor biology
• Life sciences, Hematology and oncology
• Life sciences, Medical biochemistry
• Life sciences, Pharmaceuticals - health and biochemistry
• Life sciences, Molecular biology

Papers

• Targeted genetic and small molecule disruption of N-Ras CaaX cleavage alters its localization and oncogenic potential.

  Emily R Hildebrandt; Shaneela A Hussain; Michelle A Sieburg; Rajani Ravishankar; Nadeem Asad; Sangram Gore; Takahiro Ito; James L Hougland; Timothy M Dore; Walter K Schmidt

  Bioorganic chemistry, Jun. 2024

  
• The RNA-binding protein Msi2 regulates autophagy during myogenic differentiation.

  Ruochong Wang; Futaba Kato; Rio Yasui Watson; Aaron M Beedle; Jarrod A Call; Yugo Tsunoda; Takeshi Noda; Takaho Tsuchiya; Makoto Kashima; Ayuna Hattori; Takahiro Ito

  Life science alliance, May 2024

  Access this paper :

  
• Regulation of amino acid metabolism in myeloid leukemia

  Takahiro Ito

  Cancer Science, 2021

  
• Uncovering the metabolic reprogramming of stem cell fates in leukemia

  Takahiro Ito

  Cancer Science, 2021

  
• Identification of Syndecan-1 As a Key Dependency of Myeloid Leukemia Growth and Dissemination

  Takahiro Ito

  Blood, 2018

  
• Reduced expression of Sytl 1 and Ccdc21 and impaired induction of Mt I by oxidative stress in SII-K1 knockout mice

  Takahiro Ito

  Drug Discoveries & Therapeutics, 2010

  
• Reduced expression of Sytl 1 and Ccdc21 and impaired induction of Mt I by oxidative stress in SII-K1 knockout mice.

  Takahiro Ito

  Drug Discoveries & Therapeutics, 2010

  
• Reduced expression of Sytl 1 and Ccdc21 and impaired induction of Mt I by oxidative stress in SII-K1 knockout mice.

  Tano, K; Hamamoto, H; Ito, T; Sumiya, E; Rakwal, R; Shibato, J; Masuo, Y; Ijiri, K; Sekimizu, K; Akimitsu, N

  Drug discoveries & therapeutics, 2010

  
• Lack of polymorphisms in the coding region of the highly conserved gene encoding transcription elongation factor S-II (TCEA1)

  Takahiro Ito

  Drug Discoveries & Therapeutics, 2007

  
• The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia.

  Kei Kozawa; Miho Sekai; Kenji Ohba; Shoko Ito; Hiroaki Sako; Takeshi Maruyama; Mai Kakeno; Takanobu Shirai; Keisuke Kuromiya; Tomoko Kamasaki; Koki Kohashi; Shinya Tanaka; Susumu Ishikawa; Nanami Sato; Shota Asano; Hironori Suzuki; Nobuyuki Tanimura; Yohei Mukai; Noriko Gotoh; Mishie Tanino; Shinya Tanaka; Ken Natsuga; Tomoyoshi Soga; Tomonori Nakamura; Yukihiro Yabuta; Mitinori Saitou; Takahiro Ito; Kenkyo Matsuura; Makoto Tsunoda; Toyone Kikumori; Tadashi Iida; Yasuyuki Mizutani; Yuki Miyai; Kozo Kaibuchi; Atsushi Enomoto; Yasuyuki Fujita

  Current biology : CB, 26 Jul. 2021

  
• Determination of intracellular 2-hydroxyglutarate enantiomers using two-dimensional liquid chromatography

  Takuma Ohtawa; Ayuna Hattori; Muneki Isokawa; Masashi Harada; Takashi Funatsu; Takahiro Ito; Makoto Tsunoda

  Journal of Chromatography Open, Nov. 2021

  
• Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia.

  Koji Jimbo; Ayuna Hattori; Shuhei Koide; Takahiro Ito; Katsuhiro Sasaki; Kazuhiro Iwai; Yasuhito Nannya; Atsushi Iwama; Arinobu Tojo; Takaaki Konuma

  Leukemia, 09 Nov. 2022

  
• Immunoglobulin superfamily member 8 maintains myeloid leukemia stem cells through inhibition of β-catenin degradation.

  Koji Jimbo; Yaeko Nakajima-Takagi; Takahiro Ito; Shuhei Koide; Yasuhito Nannya; Atsushi Iwama; Arinobu Tojo; Takaaki Konuma

  Leukemia, 13 Apr. 2022

  
• A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia.

  Kyle Spinler; Jeevisha Bajaj; Takahiro Ito; Bryan Zimdahl; Michael Hamilton; Armin Ahmadi; Claire S Koechlein; Nikki Lytle; Hyog Young Kwon; Ferdous Anower-E-Khuda; Hao Sun; Allen Blevins; Joi Weeks; Marcie Kritzik; Jan Karlseder; Mark H Ginsberg; Pyong Woo Park; Jeffrey D Esko; Tannishtha Reya

  Nature communications, 26 Nov. 2020, Peer-reviewed

  
• Analysis of intracellular α-keto acids by HPLC with fluorescence detection

  Takuya Fujiwara; Ayuna Hattori; Takahiro Ito; Takashi Funatsu; Makoto Tsunoda

  Analytical Methods, 21 May 2020, Peer-reviewed

  
• Continuous in vivo Metabolism by NMR

  Takahiro Ito

  Frontiers in Molecular Biosciences, 30 Apr. 2019, Peer-reviewed

  
• Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia.

  Ayuna Hattori; Makoto Tsunoda; Takaaki Konuma; Masayuki Kobayashi; Tamas Nagy; John Glushka; Fariba Tayyari; Daniel McSkimming; Natarajan Kannan; Arinobu Tojo; Arthur S Edison; Takahiro Ito

  Nature, 25 May 2017, Peer-reviewed, Corresponding author

  
• RNA binding protein MSI2 positively regulates FLT3 expression in myeloid leukemia.

  Ayuna Hattori; Daniel McSkimming; Natarajan Kannan; Takahiro Ito

  Leukemia research, Mar. 2017, Peer-reviewed, Corresponding author

  
• Analysis of Branched-Chain Keto Acids in Cell Extracts by HPLC-Fluorescence Detection

  Ayuna Hattori; Takahiro Ito; Makoto Tsunoda

  CHROMATOGRAPHY, 2017, Peer-reviewed

  
• High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo.

  Claire S Koechlein; Jeffrey R Harris; Timothy K Lee; Joi Weeks; Raymond G Fox; Bryan Zimdahl; Takahiro Ito; Allen Blevins; Seung-Hye Jung; John P Chute; Amit Chourasia; Markus W Covert; Tannishtha Reya

  Nature communications, 18 Jul. 2016, Peer-reviewed

  
• Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.

  Raymond G Fox; Nikki K Lytle; Dawn V Jaquish; Frederick D Park; Takahiro Ito; Jeevisha Bajaj; Claire S Koechlein; Bryan Zimdahl; Masato Yano; Janel Kopp; Marcie Kritzik; Jason Sicklick; Maike Sander; Paul M Grandgenett; Michael A Hollingsworth; Shinsuke Shibata; Donald Pizzo; Mark Valasek; Roman Sasik; Miriam Scadeng; Hideyuki Okano; Youngsoo Kim; A Robert MacLeod; Andrew M Lowy; Tannishtha Reya

  Nature, 16 Jun. 2016, Peer-reviewed

  
• Regulation of Stem Cell Self-Renewal and Oncogenesis by RNA-Binding Proteins; RNA PROCESSING: DISEASE AND GENOME-WIDE PROBING

  Ayuna Hattori; Kristina Buac; Takahiro Ito

  Advances in Experimental Medicine and Biology, 2016, Peer-reviewed, Invited, Corresponding author

  
• Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia.

  Hyog Young Kwon; Jeevisha Bajaj; Takahiro Ito; Allen Blevins; Takaaki Konuma; Joi Weeks; Nikki K Lytle; Claire S Koechlein; David Rizzieri; Charles Chuah; Vivian G Oehler; Roman Sasik; Gary Hardiman; Tannishtha Reya

  Cell stem cell, 06 Aug. 2015, Peer-reviewed

  
• Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration.

  William Lento; Takahiro Ito; Chen Zhao; Jeffrey R Harris; Wei Huang; Chen Jiang; Kouros Owzar; Sadhna Piryani; Luigi Racioppi; Nelson Chao; Tannishtha Reya

  Genes & development, 01 May 2014, Peer-reviewed

  
• Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia.

  Bryan Zimdahl; Takahiro Ito; Allen Blevins; Jeevisha Bajaj; Takaaki Konuma; Joi Weeks; Claire S Koechlein; Hyog Young Kwon; Omead Arami; David Rizzieri; H Elizabeth Broome; Charles Chuah; Vivian G Oehler; Roman Sasik; Gary Hardiman; Tannishtha Reya

  Nature genetics, Mar. 2014, Peer-reviewed, Lead author

  
• Stem cell maintenance and disease progression in chronic myeloid leukemia.

  Takahiro Ito

  International journal of hematology, Dec. 2013, Peer-reviewed, Invited, Corresponding author

  
• Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.

  Manabu Kurokawa; Takahiro Ito; Chih-Sheng Yang; Chen Zhao; Andrew N Macintyre; David A Rizzieri; Jeffrey C Rathmell; Michael W Deininger; Tannishtha Reya; Sally Kornbluth

  Proceedings of the National Academy of Sciences of the United States of America, 05 Feb. 2013, Peer-reviewed

  
• Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche.

  Heather A Himburg; Jeffrey R Harris; Takahiro Ito; Pamela Daher; J Lauren Russell; Mamle Quarmyne; Phuong L Doan; Katherine Helms; Mai Nakamura; Emma Fixsen; Gonzalo Herradon; Tannishtha Reya; Nelson J Chao; Sheila Harroch; John P Chute

  Cell reports, 25 Oct. 2012, Peer-reviewed

  
• β-Arrestin2 mediates the initiation and progression of myeloid leukemia.

  Mark Fereshteh; Takahiro Ito; Jeffrey J Kovacs; Chen Zhao; Hyog Young Kwon; Valerie Tornini; Takaaki Konuma; Minyong Chen; Robert J Lefkowitz; Tannishtha Reya

  Proceedings of the National Academy of Sciences of the United States of America, 31 Jul. 2012, Peer-reviewed

  
• aSIRTing control over cancer stem cells.

  Takahiro Ito; Bryan Zimdahl; Tannishtha Reya

  Cancer cell, 14 Feb. 2012, Peer-reviewed, Lead author

  
• Regulation of myeloid leukaemia by the cell-fate determinant Musashi.

  Takahiro Ito; Hyog Young Kwon; Bryan Zimdahl; Kendra L Congdon; Jordan Blum; William E Lento; Chen Zhao; Anand Lagoo; Gareth Gerrard; Letizia Foroni; John Goldman; Harriet Goh; Soo-Hyun Kim; Dong-Wook Kim; Charles Chuah; Vivian G Oehler; Jerald P Radich; Craig T Jordan; Tannishtha Reya

  Nature, 05 Aug. 2010, Peer-reviewed, Lead author

  
• Novel RNA polymerase II mutation suppresses transcriptional fidelity and oxidative stress sensitivity in rpb9Δ yeast

  Hiroshi Koyama; Tomofumi Ueda; Takahiro Ito; Kazuhisa Sekimizu

  Genes to Cells, Feb. 2010, Peer-reviewed

  
• Transcription arrest relief by S-II/TFIIS during gene expression in erythroblast differentiation

  Makiko Nagata; Takahiro Ito; Nagisa Arimitsu; Hiroshi Koyama; Kazuhisa Sekimizu

  GENES TO CELLS, Mar. 2009, Peer-reviewed

  
• Transcriptional repression of the IMD2 gene mediated by the transcriptional co-activator Sub1

  Hiroshi Koyama; Eriko Sumiya; Makiko Nagata; Takahiro Ito; Kazuhisa Sekimizu

  GENES TO CELLS, Nov. 2008, Peer-reviewed

  
• Improved method for the PCR-based gene disruption in Saccharomyces cerevisiae

  Hiroshi Koyama; Eriko Sumiya; Takahiro Ito; Kazuhisa Sekimizu

  FEMS Yeast Research, Mar. 2008, Peer-reviewed

  
• Defective FESTA/EAF2-mediated transcriptional activation in S-II-deficient embryonic stem cells

  Takahiro Ito; Kayoko Saso; Nagisa Arimitsu; Kazuhisa Sekimizu

  Biochemical and Biophysical Research Communications, 23 Nov. 2007, Peer-reviewed, Lead author

  
• Stimulation of RNA polymerase II transcript cleavage activity contributes to maintain transcriptional fidelity in yeast

  Hiroshi Koyama; Takahiro Ito; Toshiyuki Nakanishi; Kazuhisa Sekimizu

  Genes to Cells, May 2007, Peer-reviewed

  
• Antioxidant N-acetyl-l-cysteine inhibits erythropoietin-induced differentiation of erythroid progenitors derived from mouse fetal liver

  Makiko Nagata; Nagisa Arimitsu; Takahiro Ito; Kazuhisa Sekimizu

  Cell Biology International, Mar. 2007, Peer-reviewed

  
• Transcription elongation factor S-II is required for definitive hematopoiesis

  T Ito; N Arimitsu; M Takeuchi; N Kawamura; M Nagata; K Saso; N Akimitsu; H Hamamoto; S Natori; A Miyajima; K Sekimizu

  Molecular and Cellular Biology, Apr. 2006, Peer-reviewed, Lead author

  
• Direct interaction between metastasis-associated protein 1 and endophilin 3

  Y Aramaki; K Ogawa; Y Toh; T Ito; N Akimitsu; H Hamamoto; K Sekimizu; K Matsusue; A Kono; H Iguchi; S Takiguchi

  FEBS LETTERS, Jul. 2005, Peer-reviewed

  
• Participation of Rho-dependent transcription termination in oxidative stress sensitivity caused by an rpoB mutation

  Nobuyuki Kawamura; Kenji Kurokawa; Takahiro Ito; Hiroshi Hamamoto; Hiroshi Koyama; Chikara Kaito; Kazuhisa Sekimizu

  Genes to Cells, 31 Mar. 2005, Peer-reviewed

  
• GRIP1 tau, a novel PDZ domain-containing transcriptional activator, cooperates with the testis-specific transcription elongation factor SII-T1

  A Nakata; T Ito; M Nagata; S Hori; K Sekimizu

  Genes to Cells, Nov. 2004, Peer-reviewed

  
• Transcription elongation factor S-II maintains transcriptional fidelity and confers oxidative stress resistance

  H Koyama; T Ito; T Nakanishi; N Kawamura; K Sekimizu

  Genes to Cells, Oct. 2003, Peer-reviewed

  
• Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II

  K Saso; T Ito; S Natori; K Sekimizu

  Journal of Biochemistry, Apr. 2003, Peer-reviewed

  
• Gene structure and chromosome mapping of mouse transcription elongation factor S-II (Tcea1)

  T Ito; MF Seldin; MM Taketo; T Kubo; S Natori

  Gene, Feb. 2000, Peer-reviewed

  
• Gene organization and chromosome mapping of the testis-specific S-II

  T Ito; MF Seldin; MM Taketo; T Kubo; S Natori

  Mammalian Genome, Nov. 1998, Peer-reviewed, Lead author

  
• Spermatocyte-specific expression of the gene for mouse testis-specific transcription elongation factor S-II

  T Ito; QH Xu; H Takeuchi; T Kubo; S Natori

  FEBS Letters, Apr. 1996, Peer-reviewed, Lead author

  

Misc.

• ROLE OF AMINO ACID METABOLISM IN CANCER PROGRESSION

  Ayuna Hattori; Takahiro Ito

  EXPERIMENTAL HEMATOLOGY, Sep. 2016

  
• AMINO ACID METABOLISM IN MYELOID LEUKEMIA

  Ayuna Hattori; Takahiro Ito

  EXPERIMENTAL HEMATOLOGY, Sep. 2015

  
• Deficiency of the E3 Ligase Hoip Impairs Adult Hematopoiesis and Myeloid Leukemia

  Koji Jimbo; Shuhei Koide; Takahiro Ito; Arinobu Tojo; Katsuhiro Sasaki; Kazuhiro Iwai; Atsushi Iwama; Yasuhito Nannya; Takaaki Konuma

  BLOOD, Nov. 2021

  
• 糖巣特異的S-II(SII-T1)遺伝子の精巣内での発現の解析

  伊藤 貴浩; XU Qihong; 竹内 秀明; 久保 健雄; 名取 俊二

  日本分子生物学会年会プログラム・講演要旨集, 01 Aug. 1996

  
• Premature Aging-Like Phenotypes in Metastasis-Associated Protein I (Mta1) Null Mice

  S. Takiguchi; M. Yaguchi; K. Ogawa; Y. Wada; K. Matsusue; T. Ito; H. Hamamoto; N. Akimitsu; K. Sekimizu; Y. Toh; H. Iguchi

  JOURNAL OF BONE AND MINERAL RESEARCH, Sep. 2008

  
• Immunoglobulin Superfamily Member 8 Is Indispensable for Myeloid Leukemia Via Wnt/beta-Catenin Signaling Pathway

  Koji Jimbo; Takaaki Konuma; Takahiro Ito; Yaeko Nakajima-Takagi; Atsushi Iwama; Arinobu Tojo

  BLOOD, Nov. 2020

  

External funds: Kakenhi

• Mechanism and Regulation of Stem Cell Fates by the Branched-Chain Amino Acid Metabolism in Cancer

  Grant-in-Aid for Scientific Research (S)

  Broad Section I

  Kyoto University

  伊藤 貴浩

  From 05 Jul. 2021, To 31 Mar. 2026, Granted

  代謝;がん幹細胞;アミノ酸

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21H05048/
• 白血病単一細胞分岐鎖アミノ酸代謝特性解析のためのマイクロ分離分析法の開発

  Grant-in-Aid for Scientific Research (B)

  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related

  The University of Tokyo

  角田 誠

  From 01 Apr. 2021, To 31 Mar. 2024, Granted

  アミノ酸;がん;クロマトグラフィー;液体クロマトグラフィー

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21H02613/
• 黄色ブドウ球菌の滑走能低下を指標とした抗菌治療薬に関する研究

  Grant-in-Aid for Exploratory Research

  The University of Tokyo

  関水 和久

  From 01 Apr. 2007, To 31 Mar. 2008, Project Closed

  黄色ブドウ球菌;MSSA;MRSA;滑走能力;メチシリン

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19659016/
• 造血幹細胞の自己複製・多分化能の維持における転写伸長因子の機能

  Grant-in-Aid for Young Scientists (B)

  The University of Tokyo

  伊藤 貴浩

  From 01 Apr. 2006, To 31 Mar. 2008, Project Closed

  転写伸長因子;S-II;胚性幹細胞;造血

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18790047/
• 転写中断解除因子と組織特異的転写活性化因子の協調作用に基づく遺伝子発現制御機構

  Grant-in-Aid for Young Scientists (B)

  The University of Tokyo

  伊藤 貴浩

  From 01 Apr. 2003, To 31 Mar. 2006, Project Closed

  S-II;造血肝細胞;転写伸長因子;赤芽球

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15790037/
• Functions of transcription elongation factor S-II for cell stress response and development

  Grant-in-Aid for Scientific Research (A)

  The University of Tokyo

  Kazuhisa SEKIMIZU

  From 01 Apr. 2002, To 31 Mar. 2004, Project Closed

  転写因子;S-II;RNAポリメラーゼII;発生分化;遺伝子ノックアウト;酵母細胞;イースト2ハイブリット法;赤芽球分化;遺伝子ノックアウトマウス;イースト2ハイブリッド法;マウス;胎生致死;酸化ストレス;酸化型損傷塩基;転写忠実度維持, transcription factor;S-II;RNA polymerase II;development;gene knock-out;yeast cells;yeast two hybrid method;erythro differentiation

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14207097/
• マウスDNAトポイソメラーゼIIαの細胞周期制御における役割に関する分子遺伝学

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  The University of Tokyo

  関水 和久

  From 01 Apr. 2002, To 31 Mar. 2004, Project Closed

  トポイソメラーゼ;細胞周期;ノックアウトマウス;G0期;血清飢餓;シュナイダー細胞;酵母細胞;アポトーシス;DNAトポイソメラーゼ;遺伝子ノックアウトマウス;マウス初期胚;ICRF-193;RNAi;カスパーゼ;HeLa細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14033207/
• 転写伸長因子S-IIによる新しい遺伝子発現制御機構に関する研究

  Grant-in-Aid for Young Scientists (B)

  The University of Tokyo

  伊藤 貴浩

  From 01 Apr. 2001, To 31 Mar. 2003, Project Closed

  マウス;S-II;赤血球;胎生致死;カイコ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13771376/
• 疾病キラルバイオマーカー定量を指向した高感度・高精度なオンチップ分離分析法の開発

  Grant-in-Aid for Scientific Research (B)

  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related

  The University of Tokyo

  角田 誠

  From 01 Apr. 2024, To 31 Mar. 2027, Granted

  クロマトグラフィー;マイクロ流体デバイス;白血病;慢性腎臓病

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K02163/
• Understanding the molecular and cellular basis and controlling cellular phenomena: A New Concept for Intracellular Delivery of Antibodies

  Grant-in-Aid for Scientific Research (S)

  Broad Section E

  Kyoto University

  二木 史朗

  From 01 Apr. 2024, To 31 Mar. 2029, Granted

  ペプチド;抗体;細胞内送達;細胞膜透過性;細胞機能制御

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24H00051/
• AI利用型高速画像解析による核小体動態の分子解剖

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 50:Oncology and related fields

  Kyoto University

  伊藤 貴浩

  From 28 Jun. 2024, To 31 Mar. 2026, Adopted

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K22069/
• AI利用型高速画像解析による核小体動態の分子解剖

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 50:Oncology and related fields

  Kyoto University

  伊藤 貴浩

  From 28 Jun. 2024, To 31 Mar. 2026, Granted

  核小体

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K22069/

Education

Teaching subject(s)

• From 01 Apr. 2024, To 31 Mar. 2025

  ILAS Seminar

  Z001, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Pharmaceutical Biochemistry B

  8206, Spring, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Practice in Basic Molecular Biology

  4204, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Laboratory Practice in Basic Molecular Biology

  4204, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory Coaching Practice A

  8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Research Proposal Writing Practice B

  8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  International Skills Practice B

  8304, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  International Skills Practice A

  8303, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory Coaching Practice B

  8302, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Research Proposal Writing Practice A

  8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Industry-academia Collaborative Internship B

  8306, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Industry-academia Collaborative Internship A

  8305, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Medicinal Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Research in Basic Molecular Biology

  3204, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Research in Basic Molecular Biology

  3204, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Medicinal Frontier Science Research C

  8408, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Medicinal Frontier Science Research B

  8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory IV : Biochemistry and Microbiology

  C906, Fall, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Infection and Host Defense 1

  A216, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Infection and Host Defense 2

  A217, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Infection and Host Defense II

  C217, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Infection and Host Defense I

  C216, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Basic Molecular Biology Seminar

  2304, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Basic Laboratory Techniques in Biological Chemistry

  1207, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Introduction to Modern Life Sciences for Drug Discovery

  1027, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Introduction to Pharmaceutical Sciences

  6002, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Introduction to Clinical Pharmacy

  6001, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Basic Molecular Biology Seminar

  2304, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Pharmaceutical Sciences III

  6007, Fall, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Introduction to Pharmaceutical Biochemistry

  8103, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  ２１ＣＯＥ化学講義３（理）

  8001, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar on Critical Reading of Scientific Papers B

  8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  ILAS Seminar

  Z001, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Practice in Basic Molecular Biology

  4204, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Laboratory Practice in Basic Molecular Biology

  4204, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Pharmaceutical Biochemistry A

  8205, Fall, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  International Skills Practice A

  8303, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory Coaching Practice B

  8302, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory Coaching Practice A

  8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Research Proposal Writing Practice B

  8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Research Proposal Writing Practice A

  8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Industry-academia Collaborative Internship A

  8305, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Research Training(Cell Fate Dynamics and Therapeutics)

  E822, Year-long, Faculty of Pharmaceutical Sciences, 14
• From 01 Apr. 2023, To 31 Mar. 2024

  Research Training(Cell Fate Dynamics and Therapeutics)

  D165, Year-long, Faculty of Pharmaceutical Sciences, 10
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory IV : Biochemistry and Microbiology

  C906, Fall, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Molecular Genetics II

  3726, Spring, Faculty of Science, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Research in Basic Molecular Biology

  3204, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Research in Basic Molecular Biology

  3204, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Medicinal Frontier Science Research B

  8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Medicinal Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory 4 : Biochemistry and Microbiology

  A906, Fall, Faculty of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Research Training(Cell Fate Dynamics and Therapeutics)

  8164, Year-long, Faculty of Pharmaceutical Sciences, 6
• From 01 Apr. 2023, To 31 Mar. 2024

  Infection and Host Defense 2

  A217, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Infection and Host Defense 1

  A216, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Infection and Host Defense II

  C217, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Infection and Host Defense I

  C216, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar on Critical Reading of Scientific Papers B

  8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Introduction to Pharmaceutical Biochemistry

  8103, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Basic Molecular Biology Seminar

  2304, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Basic Molecular Biology Seminar

  2304, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Basic Biological Chemistry I

  1213, Fall, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  ２１ＣＯＥ化学講義３（理）

  8001, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Pharmaceutical Sciences III

  6007, Fall, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Introduction to Pharmaceutical Sciences

  6002, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Basic Laboratory Techniques in Biological Chemistry

  1207, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Introduction to Modern Life Sciences for Drug Discovery

  1027, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Pharmaceutical Biochemistry B

  8206, Spring, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory 4 : Biochemistry and Microbiology

  A906, Fall, Faculty of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Research Proposal Writing Practice A

  8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Infection and Host Defense 1

  A216, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Research Training(Cell Fate Dynamics and Therapeutics)

  8164, Year-long, Faculty of Pharmaceutical Sciences, 6
• From 01 Apr. 2022, To 31 Mar. 2023

  Research Training(Cell Fate Dynamics and Therapeutics)

  D165, Year-long, Faculty of Pharmaceutical Sciences, 10
• From 01 Apr. 2022, To 31 Mar. 2023

  Research in Basic Molecular Biology

  3204, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Infection and Host Defense 2

  A217, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory IV : Biochemistry and Microbiology

  C906, Fall, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2022, To 31 Mar. 2023

  Molecular Genetics II

  3726, Spring, Faculty of Science, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Introduction to Modern Life Sciences for Drug Discovery

  1027, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Basic Laboratory Techniques in Biological Chemistry

  1207, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory Coaching Practice A

  8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  ２１ＣＯＥ化学講義３（理）

  8001, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Infection and Host Defense I

  C216, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Laboratory Practice in Basic Molecular Biology

  4204, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Introduction to Pharmaceutical Biochemistry

  8103, Spring, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Basic Molecular Biology Seminar

  2304, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Infection and Host Defense II

  C217, Fall, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Medical Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From Apr. 2020, To Mar. 2021

  Molecular Genetics II

  Spring, 理学部
• From Apr. 2020, To Mar. 2021

  Laboratory Practice in Basic Molecular Biology

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Research in Basic Molecular Biology

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Basic Molecular Biology Seminar

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Basic Laboratory Techniques in Biological Chemistry

  Spring, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Infection and Host Defense II (Immunology and Virology)

  Fall, 薬学部
• From Apr. 2020, To Mar. 2021

  Infection and Host Defense 1

  Spring, 薬学部
• From Apr. 2020, To Mar. 2021

  Infection and Host Defense 2

  Fall, 薬学部
• From Apr. 2020, To Mar. 2021

  Infection and Host Defense I (Microbiology and Virology)

  Spring, 薬学部
• From Apr. 2020, To Mar. 2021

  Research Training(Cell Fate Dynamics and Therapeutics)

  Year-long, 薬学部
• From Apr. 2020, To Mar. 2021

  Basic Laboratory Techniques in Pharmaceutical Sciences

  Spring, 薬学研究科
• From Apr. 2021, To Mar. 2022

  ILAS Seminar :Seminar on Developmental Biology and Regenerative Medicine

  Spring, 全学共通科目
• From Apr. 2021, To Mar. 2022

  Molecular Genetics II

  Spring, 理学部
• From Apr. 2021, To Mar. 2022

  Introduction to Modern Life Sciences for Drug Discovery

  Spring, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Laboratory Practice in Basic Molecular Biology

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Research in Basic Molecular Biology

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Basic Molecular Biology Seminar

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Basic Laboratory Techniques in Biological Chemistry

  Spring, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Infection and Host Defense I

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Infection and Host Defense II

  Fall, 薬学部
• From Apr. 2021, To Mar. 2022

  Infection and Host Defense 1

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Infection and Host Defense 2

  Fall, 薬学部
• From Apr. 2021, To Mar. 2022

  Research Training(Cell Fate Dynamics and Therapeutics)

  Year-long, 薬学部
• From Apr. 2021, To Mar. 2022

  Research Training(Cell Fate Dynamics and Therapeutics)

  Year-long, 薬学部
• From Apr. 2021, To Mar. 2022

  Basic Laboratory Techniques in Pharmaceutical Sciences

  Spring, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Pharmaceutical Laboratory IV : Biochemistry and Microbiology

  Fall, 薬学部
• From Apr. 2021, To Mar. 2022

  Pharmaceutical Laboratory 4 : Biochemistry and Microbiology

  Fall, 薬学部

Participation in PhD Defense

• Combination therapy with EGFR tyrosine kinase inhibitors and TEAD inhibitor increases tumor suppression effects in EGFR mutation-positive lung cancer

  OGIMOTO TATSUYA, Graduate School of Medicine, Chief Examiner

  25 Mar. 2024
• Brg1 controls stemness and metastasis of pancreatic cancer through regulating hypoxia pathway

  ARAKI OSAMU, Graduate School of Medicine, Sub-chief Examiner

  25 Mar. 2024
• Deep generative design of RNA family sequences

  SUMI SHUNSUKE, Graduate School of Medicine, Sub-chief Examiner

  25 Mar. 2024
• Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz

  YAMADA SHINNOSUKE, Graduate School of Medicine, Sub-chief Examiner

  25 Mar. 2024
• Beta-1,4-galactosyltransferase-3 deficiency suppresses the growth of immunogenic tumors in mice

  WEI Heng, Graduate School of Medicine, Chief Examiner

  23 Jan. 2024
• Serum amyloid alpha 1-2 are not required for liver inflammation in the 4T1 murine breast cancer model

  HE CHENFENG, Graduate School of Medicine, Chief Examiner

  23 May 2023
• Bmal1 Regulates Prostate Growth via Cell-Cycle Modulation

  UEDA MASAKATSU, Graduate School of Medicine, Sub-chief Examiner

  25 Sep. 2023
• Novel and efficient method for culturing patient-derived gastric cancer stem cells

  MORIMOTO TOMONORI, Graduate School of Medicine, Sub-chief Examiner

  25 Sep. 2023
• Calcium sparks enhance the tissue fluidity within epithelial layers and promote apical extrusion of transformed cells

  KUROMIYA KEISUKE, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2023
• Remote solid cancers rewire hepatic nitrogen metabolism via host nicotinamide-N-methyltransferase

  MIZUNO RIN, Graduate School of Medicine, Chief Examiner

  23 Mar. 2023
• A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice

  YAMAMOTO ETSUKO, Graduate School of Medicine, Chief Examiner

  23 Mar. 2023
• 臨床ビッグデータ解析及び薬理学的実証によるジペプチジルペプチダーゼ4阻害薬誘発類天疱瘡抑制法の創出

  NOZAWA KEISUKE, Graduate School of Pharmaceutical Sciences, Sub-chief Examiner

  23 Mar. 2023
• Inhibition of Dopamine Receptor D1 Signaling Promotes Human Bile Duct Cancer Progression via WNT signaling

  YOGO AKITADA, Graduate School of Medicine, Chief Examiner

  23 Mar. 2023
• ILF2 enhances the DNA cytosine deaminase activity of tumor mutator APOBEC3B in multiple myeloma cells

  KAZUMA YASUHIRO, Graduate School of Medicine, Chief Examiner

  26 Sep. 2022
• Oncogenic FGFR1 mutation and amplification in common cellular origin in a composite tumor with neuroblastoma and pheochromocytoma

  TASAKA KEIJI, Graduate School of Medicine, Sub-chief Examiner

  26 Sep. 2022
• 3D epigenome dynamics in normal and stalled development

  HU BO, Graduate School of Medicine, Sub-chief Examiner

  26 Sep. 2022
• HER2 G776S mutation promotes oncogenic potential in colorectal cancer cells when accompanied by loss of APC function

  MITANI YOSUKE, Graduate School of Medicine, Chief Examiner

  26 Sep. 2022
• Role of the RNA binding protein Musashi2 in myogenesis

  Wang Ruochong, Graduate School of Pharmaceutical Sciences, Chief Examiner

  26 Sep. 2022
• CXCL13-producing CD4+ T cells accumulate in the early phase of tertiary lymphoid structures in ovarian cancer

  UKITA MASAYO, Graduate School of Medicine, Sub-chief Examiner

  26 Sep. 2022
• SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2

  MASUO KENJI, Graduate School of Medicine, Sub-chief Examiner

  25 Jul. 2022
• Amplified EPOR/JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia

  TAKEDA JUNE, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2023
• CDH18 is a fetal epicardial biomarker regulating differentiation towards vascular smooth muscle cells

  Julia Junghof, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2022
• APOBEC3B is preferentially expressed at the G2/M phase of cell cycle.

  HIRABAYASHI SHIGEKI, Graduate School of Medicine, Chief Examiner

  24 May 2021
• Establishment and characterization of a novel treatment-related neuroendocrine prostate cancer cell line KUCaP13

  OKASHO KOSUKE, Graduate School of Medicine, Sub-chief Examiner

  24 Jan. 2022
• SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization

  SUWA TATSUYA, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2022
• グルコース飢餓におけるアミノ酸トランスポーターxCTを介したEphA2リガンド非依存的シグナルの制御

  TERAMOTO KOJI, Graduate School of Pharmaceutical Sciences, Sub-chief Examiner

  23 Mar. 2022
• Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion

  OKUMURA SHINTARO, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2022
• PDK2 leads to cisplatin resistance through suppression of　mitochondrial function in ovarian clear cell carcinoma

  KITAMURA SACHIKO, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2022
• Rb and p53 Execute Distinct Roles in the Development of Pancreatic Neuroendocrine Tumors

  YAMAUCHI　YUKI, Graduate School of Medicine, Sub-chief Examiner

  24 May 2021
• Suppression of malignant rhabdoid tumors through Chb-M′-mediated RUNX1 inhibition

  DAIFU TOMOO, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2022
• Indolent feature of Helicobacter pylori-uninfected intramucosal signet ring cell carcinomas with CDH1 mutations

  NIKAIDO MITSUHIRO, Graduate School of Medicine, Sub-chief Examiner

  24 Sep. 2021

Part-time lecturer

• From 01 Jul. 2024, To 30 Jun. 2025

  Developmental and Regenerative Biology

  香港中文大学
• From 01 Oct. 2023, To 31 Mar. 2024

  疾患生物学特論

  東京大学, 大学院薬学系研究科
• From 01 Apr. 2023, To 31 Mar. 2024

  医科学特論Ⅰ

  東京大学
• From 05 Apr. 2022, To 31 Mar. 2023

  熊本大学

Administration

School management (title, position)

• From 01 Apr. 2024

  白眉センター　プログラムマネジャー
• From 01 Jan. 2023

  Amgen Scholars Program タスクフォース委員

Faculty management (title, position)

• From 01 Apr. 2024

  iSAL 運営委員
• From 01 Apr. 2024

  自己点検・評価委員会　委員
• From 01 Apr. 2024

  広報委員会　委員
• From 01 Apr. 2024

  医生物学研究所　研究支援室　広報ユニット
• From 01 Oct. 2023

  将来構想委員会　委員
• From 20 Jul. 2023

  学術委員会　委員
• From 01 Apr. 2024

  医生物学研究所　研究支援室　共同利用機器ユニット　ユニット長
• From 01 May 2021, To 31 Mar. 2024

  共同利用機器等委員会　委員長
• From 01 Apr. 2022, To 05 Jan. 2024

  研究データ保全委員会　委員
• From 01 Apr. 2022

  ウイルス・幹細胞システム医生物学共同研究拠点専門委員会　委員
• From 01 Jul. 2022

  再生実験動物施設飼育室施設運営委員会 委員
• From 01 Apr. 2020, To 01 Apr. 2021

  共同利用機器等委員会　委員
• From 01 Feb. 2024, To 31 Jul. 2024

  医学研究科　論文選定委員会委員長
• From 01 Feb. 2024, To 31 Jul. 2024

  医学研究科　運営委員会委員
• From 01 Aug. 2023, To 31 Jul. 2024

  医学研究科　論文選定委員会委員
• From 01 Oct. 2020, To 30 Sep. 2022

  医学研究科　運営委員会委員