Basic Information

Professional Memberships

• From Nov. 2021, To Present

  Society for Health Data Science
• From Jun. 2021, To Present

  The Japanese Society of. Clinical Pharmacology and Therapeutics
• From Dec. 1992, To Present

  The Japan Stroke Society
• From Dec. 1991, To Present

  The Japanese Society of Internal Medicine
• From Oct. 2015, To Present

  Japan Society of Clinical Trials and Research

Academic Degree

• MD, PhD(Osaka University)

Profile

• Profile

  Nagai studied both pharmaceutical sciences at Univ. of Tokyo (1982 -1987) and medicine at Osaka Univ. Medical School (1987–1991). After completing residency, he worked as a stroke neurologist at a general hospital (1992-1996) and later at Osaka Univ. Hospital (1998-2003). Also, as a Visiting Fellow at the National Institutes of Health in US (1996-1998), he engaged in a large clinical study and received the relevant trainings. Thereafter, he worked at the Translational Research Informatics Center (since 2003) and Kobe University Hospital (since 2015), and is currently working at Kyoto University Hospital (since 2021), with the primary commitment to the consolidation of national and institutional infrastructure for promoting clinical and translational researches, as well as to the facilitation of individual research projects.

Language of Instruction

• Japanese

ID,URL

• ORCID ID

  0000-0002-0836-0495

• J-Global ID

  201501020051741452

researchmap URL

• https://researchmap.jp/7000013832

Research

Research Topics, Overview of the research

• Research Topics

  Study on the logics and ethics of clinical science, Study on the infrastructure and methodologies of clinical science

• Overview of the research

  Clinical researches play a crucial role for the development of new medicine and optimization of current medicine. Indeed, no matter how good ideas are born in the clinic, they do not lead to the therapeutic improvements, unless they are substantiated by clinical researches. Particularly, researches with interventions are the human projects underpinned by the dedication of patients, the prerequisite of which is human right protection, and the results of which should be shared by all people. Also, because the results are directly reflected in medicine, clinical researches must not be harmful both to the current and future patients, which are ensured by the scientific validity and data credibility. Inversely, unreliable or fake results will mislead people, posing serious threats to the public welfare. Then, each research must be implemented through scientifically and ethically righteous methodologies, requiring interdisciplinary approaches based on the principle of clinical science. Thus, we are dedicated to the cultivation of scientific principles underpinning the processes, as well as to the facilitation of respective clinical researches.

Research Areas

• Life sciences, Neurology
• Life sciences, Healthcare management, medical sociology

Papers

• Pivotal trial of low-intensity pulsed ultrasound therapy for early Alzheimer's disease: Rationale and design

  Hiroaki Shimokawa; Masahiro Akishita; Masafumi Ihara; Satoshi Teramukai; Aiko Ishiki; Yoji Nagai; Masanori Fukushima

  Journal of Alzheimer's Disease Reports, Jan. 2025

  
• Randomized Controlled Trial of Cilostazol Addition for In-Stent Restenosis After Carotid Artery Stenting

  Hiroshi Yamagami; Tomohiko Ozaki; Kuniaki Ogasawara; Izumi Nagata; Yuji Matsumaru; Shinichi Yoshimura; Makoto Sasaki; Kazuyuki Nagatsuka; Kazuo Minematsu; Yoji Nagai; Chiaki Sakai; Yasushi Matsumoto; Masayuki Ezura; Hideyuki Ishihara; Nobuyuki Sakai

  Stroke, Dec. 2024

  
• Efficacy of a non-pharmaceutical multimodal intervention program in a group setting for patients with mild cognitive impairment: A single-arm interventional study with pre-post and external control analyses

  Satoshi Nakagawa; Hisatomo Kowa; Yumi Takagi; Yasumasa Kakei; Tatsuo Kagimura; Shoji Sanada; Yoji Nagai

  Contemporary Clinical Trials Communications, Aug. 2024

  
• Changing paradigms of periprocedural antithrombotic therapy in neuroendovascular therapy: Analysis of JR-NET 3

  Yukiko Enomoto; Japanese Registry of Neuroendovascular Therapy (JR-NET) investigators; Daisuke Mizutani; Shinichi Yoshimura; Nobuyuki Sakai; Nobuyuki Sakai; Koji Iihara; Tetsu Satow; Masayuki Ezura; Akio Hyodo; Shigeru Miyachi; Susumu Miyamoto; Yoji Nagai; Kunihiro Nishimura; Kazunori Toyoda; Toshiyuki Fujinaka; Toshio Higashi; Masaru Hirohata; Akira Ishii; Hirotoshi Imamura; Yasushi Ito; Naoya Kuwayama; Hidenori Oishi; Yuji Matsumaru; Yasushi Matsumoto; Ichiro Nakahara; Chiaki Sakai; Kenji Sugiu; Tomoaki Terada; Shinichi Yoshimura

  Neurologia Medico-Chirurgica, 2019

  
• Clinical trials of medical devices for intra-cerebrovascular treatment and experiments of multi-institutional joint research

  Chiaki Sakai; Nobuyuki Sakai; Haruko Yamamoto; Yoji Nagai; Shinichi Yoshimura; Hirotoshi Imamura

  Japanese Pharmacology and Therapeutics, 2017

  
• Parent artery occlusion for unruptured cerebral aneurysms: Results of the Japanese registry of neuroendovascular therapy 3

  Hidehisa Nishi; Akira Ishii; Tetsu Satow; Koji Iihara; Nobuyuki Sakai; Masayuki Ezura; Akio Hyodo; Shigeru Miyachi; Susumu Miyamoto; Yoji Nagai; Kunihiro Nishimura; Kazunori Toyoda; Toshiyuki Fujinaka; Toshio Higashi; Masaru Hirohata; Hirotoshi Imamura; Yasushi Ito; Naoya Kuwayama; Hidenori Oishi; Yuji Matsumaru; Yasushi Matsumoto; Ichiro Nakahara; Chiaki Sakai; Kenji Sugiu; Tomoaki Terada; Shinichi Yoshimura; Japanese Registry of Neuroendovascular Therapy (JR-NET) investigators

  Neurologia Medico-Chirurgica, 2019

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• Endovascular treatment for vasospasm after aneurysmal subarachnoid hemorrhage based on data of JR-NET3

  Hirotoshi Imamura; Nobuyuki Sakai; Tetsu Satow; Koji Iihara; Masayuki Ezura; Akio Hyodo; Shigeru Miyachi; Susumu Miyamoto; Yoji Nagai; Kunihiro Nishimura; Kazunori Toyoda; Toshiyuki Fujinaka; Toshio Higashi; Masaru Hirohata; Akira Ishii; Yasushi Ito; Naoya Kuwayama; Hidenori Oishi; Yuji Matsumaru; Yasushi Matsumoto; Ichiro Nakahara; Chiaki Sakai; Kenji Sugiu; Tomoaki Terada; Shinichi Yoshimura; JR-NET investigators

  Neurologia Medico-Chirurgica, 2018

  
• Tooth Loss as a Predictor of Long-Term Care Requirements in the Elderly: A Study in Kobe City, Japan.

  Yasumasa Kakei; Tatsuo Kagimura; Yasuji Yamamoto; Tohmi Osaki; Hiroyuki Kajita; Shinsuke Kojima; Hisatomo Kowa; Miyuki Kawabata; Takumi Hasegawa; Masaya Akashi; Yoji Nagai

  Cureus, Dec. 2023

  
• 【橋渡し研究の推進】主要国における橋渡し研究推進体制 わが国の競争力強化に向けて

  永井 洋士

  Precision Medicine, Nov. 2020

  
• 【ディオバン事件のもたらしたもの】アカデミア臨床研究規制の歴史と今後の方向性 ディオバン事件の教訓と臨床研究法の課題

  永井 洋士

  薬剤疫学, Aug. 2019

  
• Preliminary evaluation of the Japanese version of the Cognitive Function Instrument in a memory clinic(和訳中)

  Osaki Tohmi; Yamamoto Yasuji; Kowa Hisatomo; Kojima Shinsuke; Maeda Kiyoshi; Kajita Hiroyuki; Kakei Yasumasa; Nagai Yoji

  日本認知症予防学会誌, Mar. 2022, Peer-reviewed

  
• Implication of using cognitive function-related simple questions to stratify the risk of long-term care need: population-based prospective study in Kobe, Japan.

  Shinsuke Kojima; Takashi Kikuchi; Yasumasa Kakei; Hisatomo Kowa; Yasuji Yamamoto; Hiroyuki Kajita; Tohmi Osaki; Masanori Fukushima; Ryoma Kayano; Yoji Nagai

  Health research policy and systems, 29 Nov. 2022, Peer-reviewed, Last author

  
• Effect of Treating Hyperphosphatemia With Lanthanum Carbonate vs Calcium Carbonate on Cardiovascular Events in Patients With Chronic Kidney Disease Undergoing Hemodialysis

  Hiroaki Ogata; Masafumi Fukagawa; Hideki Hirakata; Tatsuo Kagimura; Masanori Fukushima; Tadao Akizawa; Masashi Suzuki; Yoshiki Nishizawa; Chikao Yamazaki; Shiro Tanaka; Shuzo Kobayashi; Issei Komuro; Kazuhiko Tsuruya; Hideki Fujii; Hirotaka Komaba; Masatomo Taniguchi; Takeshi Hasegawa; Takayuki Hamano; Masahide Mizobuchi; Takashi Akiba; Ryoichi Ando; Kunitoshi Iseki; Masaaki Inaba; Takatoshi Kakuta; Hitoshi Kato; Hideki Kawanishi; Eriko Kinugasa; Fumihiko Koiwa; Takashi Shigematsu; Tetsuo Shoji; Yoshiharu Tsubakihara; Yoshihiro Tominaga; Masaaki Nakayama; Ichiei Narita; Shinichi Nishi; Kosaku Nitta; Jun Minakuchi; Keitaro Yokoyama; Yuzo Watanabe; Noritomo Itami; Tetsuo Komota; Kenji Yuasa; Akimi Uehata; Ikuo Takahashi; Mikihiko Fujishima; Kazutaka Kukita; Ibuki Yajima; Kanji Shishido; Noriko Toshima; Masato Oroku; Tomoki Yonaha; Koshi Goto; Kazuyuki Maeno; Motoko Tanaka; Tomoko Okuda; Hiroyuki Tamura; Tokihiko Sawada; Senji Okuno; Masaki Fukushima; Takashi Sekiguchi; Kazuyoshi Nakamura; Ryuji Suzuki; Teruo Kowatari; Ikuto Masakane; Minoru Ito; Hirofumi Hashimoto; Hiroaki Ogata; Ryuji Aoyagi; Sumi Hidaka; Jun Mizuguchi; Toshio Shinoda; Kenji Tanaka; Shohei Sawada; Takahiro Kawakami; Masayuki Iyoda; Yuki Shindo; Yoshiko Tanaka; Masakazu Otsuka; Makoto Watanabe; Yoshihiro Tsujimoto; Yoshihiko Ohtsubo; Shigeki Okada; Akio Yokochi; Naoto Kobayashi; Tomoki Morikawa; Harumichi Higashi; Hiroshi Asakura; Masanori Mukai; Hidetoshi Kanai; Tateki Kitaoka; Masaki Kobayashi; Ryo Karasawa; Toru Sanai; Michio Kuwahara; Satomi Shikuma; Keiko Takahashi; Masuo Tokoo; Shoji Koga; Yoko Hayami; Tetsuro Michihata; Zenzo Fujii; Yasushi Suto; Kazunori Ogiu; Yoshiko Chida; Tetsuro Takeda; Yuji Takatori; Soichi Uekihara; Keiji Kono; Ken Kitamura; Yuriko Yonekura; Akira Okuyama; Naoki Hamazaki; Tatsuo Iizumi; Kenichiro Shigemoto; Hideki Ikenaga; Toru Kawai; Kenichi Saito; Noriko Minamisono; Masahiro Tominaga; Takashi Miyamoto; Hideo Kobayashi; Hajime Yamazaki; Takashi Ishimatsu; Dai Matsuo; Hirofumi Ikeda; Kei Hori; Nobuaki Shinozaki; Norimitsu Kurogi; Noriyuki Ozawa; Shizuo Hatashita; Akio Imada; Tomohiko Naruse; Isoji Sasagawa; Kanyu Miyamoto; Masabumi Yoshino; Akihiko Shirahama; Chihiro Shirahama; Katsufumi Sakata; Tatsuji Kashiki; Shohei Nakanishi; Muneo Tomizawa; Hideki Ueno; Kazuhiro Harada; Toyonori Saiki; Keita Kimura; Yasuhiro Horii; Kazuhiro Suzuki; Naoki Hamaguchi; Akira Nakamura; Morihiro Kondo; Seikon Kin; Shoji Sanma; Yoshinori Tanaka; Shin Hasegawa; Satoru Fujimi; Akira Takehara; Yasuko Yuasa; Yuko Shibuya; Naoaki Hayama; Yasunori Nakashima; Tomoko Teramura; Yoshifumi Inada; Yuji Oyabu; Naofumi Ikeda; Fumiaki Kumagai; Tetsuhiko Yoshida; Takahito Nasu; Yutaka Watanabe; Naoyuki Kobayashi; Masaki Kohara; Yoshihiro Tani; Kei Fukami; Akira Onozaki; Yutaka Nakajima; Masahito Tamura; Kenjiro Kumakawa; Kiyoshi Ikeda; Jun Suzuki; Tsutomu Sanaka; Yoshikazu Onda; Kazo Kaizu; Futoshi Oikawa; Hiromitsu Noto; Takahiko Sato; Akihisa Yamazaki; Yoshiyuki Oshiro; Shuzo Yamamoto; Chie Ogawa; Fumiyoshi Nakayama; Kenichi Motomura; Takao Tanaka; Ryoji Hagiwara; Kazuaki Takahashi; Nobukazu Suzuki; Shinya Kobayashi; Koji Tomori; Keigo Shibagaki; Tatsuhiko Kamata; Takashi Ariyoshi; Hiroyuki Hyakutake; Suguru Matsui; Makoto Takano; Kenji Ito; Toshiaki Murata; Hidekazu Okamoto; Masahiko Ogihara; Hisashi Terajima; Takashi Uchida; Sohei Morita; Masato Nishioka; Hironori Nakamura; Yutaka Kanno; Kazuhiro Fujisawa; Yutaka Tachiki; Mitsunori Yasuda; Motoko Yanagita; Kimio Tomita; Naoaki Kanamori; Hideki Takano; Fukuji Takeda; Masashi Kaneko; Yoshihisa Inukai; Akifumi Hirata; Hirotake Kasuga; Tatsuaki Watanabe; Hironobu Miyai; Kunihiko Natori; Toshimitsu Sato; Joji Takada; Yasunori Suga; Kazuo Miyatani; Keitaro Iijima; Tsutomu Tanaka; Teruhiro Nakada; Takashi Sato; Fumiko Fukuchi; Yoshinobu Hamasaki; Yoshifumi Wada; Nobuyuki Suzuki; Masami Hashimoto; Noriko Kaburagi; Matsuhiko Suenaga; Tomohide Nomura; Toshihito Haba; Kazutaka Murakami; Keizo Kitano; Keiichi Kono; Tomio Suzuki; Fusae Deguchi; Tatsuya Nonaka; Yuko Ozawa; Kenji Maeda; Satoshi Sugiyama; Gen Konemori; Masao Mizuno; Yasunobu Shimano; Kunihiro Nabeshima; Sadahiko Hiramatsu; Yoshiyasu Iida; Yoshinari Tsuruta; Naoto Kawamura; Etsuko Kumagai; Masato Tsuboi; Wataru Tsukada; Yoshihiro Nakamura; Makoto Miyasaka; Hironori Kawamura; Takeyuki Hiramatsu; Susumu Uda; Haruki Wakai; Yasue Obi; Tetsuya Imai; Shigeru Miyahara; Kazuto Sato; Shunji Miura; Kazunobu Sugimura; Takashi Miyazaki; Kiichiro Ueno; Kazuhiro Yoshimine; Tetsuya Hashimoto; Satoru Yamazaki; Hiroyuki Kobayashi; Masuo Terashima; Tomomasa Oguchi; Masahiro Mori; Manabu Kuse; Tetsuo Chiba; Takayasu Taira; Yasuo Futoo; Takayoshi Hamada; Masanobu Horie; Kohei Miura; Tetsushi Nagai; Takehiko Muramatsu; Shuhei Tozawa; Hiroya Mukai; Kosei Kurosawa; Junko Takahashi; Naoki Matsuhashi; Aiji Yajima; Takeshi Furukawa; Yuji Ishida; Masahiro Miyata; Yukihiko Miyata; Takako Ohtsuka; Makoto Hasegawa; Hirofumi Tamai; Tetsuro Yoshioka; Hiroshi Shiozaki; Toru Takemura; Takashi Mori; Isao Aoyama; Takako Sawasaki; Daisuke Nakayama; Katsuhide Toyama; Sumiko Ito; Mayuri Ichinose; Kyoko Inoue; Kazuyoshi Kataoka; Shinji Ako; Akihiro Nagamoto; Tatsuro Arii; Kosuke Masutani; Yoshie Sasatomi; Naoki Tachibana; Atsuhiko Kawamoto; Hideaki Kaneda; Shinsuke Kojima; Miyuki Matsuo; Mikio Yoshidomi; Yoko Nakagawa; Kenichi Kohno; Emiko Uno; Tomoko Shinno; Yoji Nagai; Kaori Kuronaka; Yoichiro Nishimura; Satoshi Nakagawa; Mitsuru Maeda; Hideki Nogi; Masanori Nishi

  JAMA, 18 May 2021, Peer-reviewed

  
• がん在宅医療Web検索システムの構築

  貞池 哲志; 多田 春江; 永井 洋士; 福島 雅典

  日本在宅医学会雑誌, Oct. 2004

  
• The effect of a multimodal dementia prevention program involving community-dwelling elderly.

  Hiroyuki Kajita; Kiyoshi Maeda; Tohmi Osaki; Yasumasa Kakei; Kavita U Kothari; Yoji Nagai

  Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, Jan. 2022, Last author

  
• Kobe project for the exploration of newer strategies to reduce the social burden of dementia: a study protocol of cohort and intervention studies.

  Yoji Nagai; Shinsuke Kojima; Hisatomo Kowa; Yasuji Yamamoto; Hiroyuki Kajita; Tohmi Osaki; Yasumasa Kakei; Kavita U Kothari; Ryoma Kayano

  BMJ open, 18 Jun. 2021, Peer-reviewed, Lead author

  
• Effect of Statin on Stroke Recurrence Prevention at Different Infarction Locations: A Post Hoc Analysis of The J-STARS Study.

  Tomohisa Nezu; Naohisa Hosomi; Kazuo Kitagawa; Yoji Nagai; Yoko Nakagawa; Shiro Aoki; Tatsuo Kagimura; Hirofumi Maruyama; Hideki Origasa; Kazuo Minematsu; Shinichiro Uchiyama; Masayasu Matsumoto

  Journal of atherosclerosis and thrombosis, 25 Sep. 2019, Peer-reviewed

  
• Different Influences of Statin Treatment in Preventing At-Risk Stroke Subtypes: A Post Hoc Analysis of J-STARS.

  Naohisa Hosomi; Kazuo Kitagawa; Yoji Nagai; Yoko Nakagawa; Shiro Aoki; Tomohisa Nezu; Tatsuo Kagimura; Hirofumi Maruyama; Hideki Origasa; Kazuo Minematsu; Shinichiro Uchiyama; Masayasu Matsumoto

  Journal of atherosclerosis and thrombosis, 18 Sep. 2019, Peer-reviewed

  
• A comparison of the prevalence and risk factors of complications in intracranial tumor embolization between the Japanese Registry of NeuroEndovascular Therapy 2 (JR-NET2) and JR-NET3

  Tomohito Hishikawa; Kenji Sugiu; Satoshi Murai; Yu Takahashi; Naoya Kidani; Shingo Nishihiro; Masafumi Hiramatsu; Isao Date; Tetsu Satow; Koji Iihara; Nobuyuki Sakai; Akio Hyodo; Shigeru Miyachi; Yoji Nagai; Chiaki Sakai; Tetsu Satoh; Waro Taki; Tomoaki Terada; Masayuki Ezura; Toshio Hyogo; Shunji Matsubara; Kentaro Hayashi; Toshiyuki Fujinaka; Yasushi Ito; Shigeki Kobayashi; Masaki Komiyama; Naoya Kuwayama; Yuji Matsumaru; Yasushi Matsumoto; Yuichi Murayama; Ichiro Nokahara; Shigeru Nemoto; Koichi Sato; Shinichi Yoshimura; Susumu Miyamoto; Kunihiro Nishimura; Kazunori Toyoda; Masaru Hirohata; Akira Ishii; Hirotoshi Imamura; Hidenori Oishi

  ACTA NEUROCHIRURGICA, Aug. 2019, Peer-reviewed

  
• Assessing long-term care risk in older individuals with possible cognitive decline: A large population-based study using the Kihon Checklist.

  Shinsuke Kojima; Kenta Murotani; Bin Zhou; Kavita U Kothari; Masanori Fukushima; Yoji Nagai

  Geriatrics & gerontology international, Jul. 2019, Peer-reviewed

  
• Baseline carotid intima-media thickness and stroke recurrence during secondary prevention with pravastatin

  Wada S; Koga M; Minematsu K; Toyoda K; Suzuki R; Kagimura T; NAGAI YOJI; Aoki S; Nezu T; Hosomi N; Origasa H; Ohtsuki T; Maruyama H; Yasaka M; Kitagawa K; Uchiyama S; Matsumoto M

  Stroke, Jun. 2019, Peer-reviewed

  
• Japanese Surveillance of Neuroendovascular Therapy in JR-NET - Part II. Japanese Registry of NeuroEndovascular Treatment 3. Main Report.

  Nobuyuki Sakai; Kazutaka Uchida; Koji Iihara; Tetsu Satow; Masayuki Ezura; Akio Hyodo; Shigeru Miyachi; Susumu Miyamoto; Yoji Nagai; Kunihiro Nishimura; Kazunori Toyoda; Shinichi Yoshimura; Hirotoshi Imamura; Chiaki Sakai; Yuji Matsumaru

  Neurologia medico-chirurgica, 15 Mar. 2019

  
• Japanese Surveillance of Neuroendovascular Therapy in JR-NET - Part II. Japanese Registry of NeuroEndovascular Treatment 3. Main Report

  Sakai N; Uchida K; Iihara K; Satow T; Ezura M; Hyodo A; Miyachi S; Miyamoto S; NAGAI YOJI; Nishimura K; Toyoda K; Yoshimura S; Imamura H; Sakai C; Matsumaru Y; Japanese Registry of; NeuroendovascularTherapy (JR-NET) investigators

  Neurol Med Chir (Tokyo), Mar. 2019, Peer-reviewed

  
• Cumulative Effects of LDL Cholesterol and CRP Levels on Recurrent Stroke and TIA

  Kitagawa K; Hosomi N; NAGAI YOJI; Kagimura T; Ohtsuki T; Maruyama H; Origasa H; Minematsu K; Uchiyama S; Nakamura M; Matsumoto M; J-STARS collaborators

  J Atheroscler Thromb, Mar. 2019, Peer-reviewed

  
• One-year Outcome of Shanghai Mild Cognitive Impairment Cohort Study

  Zhou B; Zhao Q; Kojima S; Ding D; Higashide S; NAGAI YOJI; Guo Q; Kagimura T; Fukushima M; Hong Z

  Curr Alzheimer Res, 2019, Peer-reviewed

  
• Desirable Low-Density Lipoprotein Cholesterol Levels for Preventing Stroke Recurrence: A Post Hoc Analysis of the J-STARS Study (Japan Statin Treatment Against Recurrent Stroke)

  Hosomi N; Kitagawa K; NAGAI YOJI; Nakagawa Y; Aoki S; Nezu T; Kagimura T; Maruyama H; Origasa H; Minematsu K; Uchiyama S; Matsumoto M; J-STARS Collaborators

  Stroke, Apr. 2018, Peer-reviewed

  
• Ten-year standardization of lipids and high-sensitivity C-reactive protein in a randomized controlled trial to assess the effects of statins on secondary stroke prevention: Japan Statin Treatment Against Recurrent Stroke

  Masakazu Nakamura; Tatsuyuki Fukukawa; Kazuo Kitagawa; Yoji Nagai; Naohisa Hosomi; Kazuo Minematsu; Shinichiro Uchiyama; Masayasu Matsumoto; Yoshihiro Miyamoto; for J-STARS collaborators

  Annals of Clinical Biochemistry, 01 Jan. 2018, Peer-reviewed

  
• Factors associated with intima-media complex thickness of the common carotid artery in Japanese noncardioembolic stroke patients with hyperlipidemia: The J-STARS echo study

  Shinichi Wada; Masatoshi Koga; Kazunori Toyoda; Kazuo Minematsu; Masahiro Yasaka; Yoji Nagai; Shiro Aoki; Tomohisa Nezu; Naohisa Hosomi; Tatsuo Kagimura; Hideki Origasa; Kenji Kamiyama; Rieko Suzuki; Toshiho Ohtsuki; Hirofumi Maruyama; Kazuo Kitagawa; Shinichiro Uchiyama; Masayasu Matsumoto; The Japan Statin Treatment Against Recurrent Stroke (J-Stars) Echo Study Collaborators

  Journal of Atherosclerosis and Thrombosis, 2018, Peer-reviewed

  
• Long-term effect of pravastatin on carotid intima-media complex thickness the J-STARS Echo Study (Japan Statin Treatment Against Recurrent Stroke)

  Masatoshi Koga; Kazunori Toyoda; Kazuo Minematsu; Masahiro Yasaka; Yoji Nagai; Shiro Aoki; Tomohisa Nezu; Naohisa Hosomi; Tatsuo Kagimura; Hideki Origasa; Kenji Kamiyama; Rieko Suzuki; Toshiho Ohtsuki; Hirofumi Maruyama; Kazuo Kitagawa; Shinichiro Uchiyama; Masayasu Matsumoto

  Stroke, 2018, Peer-reviewed

  
• Pravastatin reduces the risk of atherothrombotic stroke when administered within six months of an initial stroke event

  Naohisa Hosomi; Yoji Nagai; Kazuo Kitagawa; Yoko Nakagawa; Shiro Aoki; Tomohisa Nezu; Tatsuo Kagimura; Hirofumi Maruyama; Hideki Origasa; Kazuo Minematsu; Shinichiro Uchiyama; Masayasu Matsumoto; J-STARS collaborators

  Journal of Atherosclerosis and Thrombosis, 2018, Peer-reviewed

  
• プラバスタチン長期投与による頸動脈内中膜複合体厚への影響 J-STARS Echo研究

  古賀 政利; 豊田 一則; 峰松 一夫; 矢坂 正弘; 永井 洋士; 細見 直永; 折笠 秀樹; 北川 一夫; 内山 真一郎; 松本 昌泰

  Neurosonology, Jun. 2017

  
• The Japan Statin Treatment Against Recurrent Stroke (J-STARS) Echo Study: Rationale and Trial Protocol

  Kazunori Toyoda; Kazuo Minematsu; Masahiro Yasaka; Yoji Nagai; Naohisa Hosomi; Hideki Origasa; Kazuo Kitagawa; Shinichiro Uchiyama; Masatoshi Koga; Masayasu Matsumoto

  JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, Mar. 2017, Peer-reviewed

  
• Reduction in high-sensitivity C-reactive protein levels in patients with ischemic stroke by statin Treatment: Hs-CRP Sub-Study in J-STARS

  Kazuo Kitagawa; J-STARS Investigators; Naohisa Hosomi; Yoji Nagai; Tatsuo Kagimura; Toshiho Ohtsuki; Hideki Origasa; Kazuo Minematsu; Shinichiro Uchiyama; Masakazu Nakamura; Masayasu Matsumoto

  Journal of Atherosclerosis and Thrombosis, 2017, Peer-reviewed

  
• Specific clinical signs and symptoms are predictive of clinical course in sporadic Creutzfeldt-Jakob disease

  E. Nakatani; Y. Kanatani; H. Kaneda; Y. Nagai; S. Teramukai; T. Nishimura; B. Zhou; S. Kojima; H. Kono; M. Fukushima; T. Kitamoto; H. Mizusawa

  EUROPEAN JOURNAL OF NEUROLOGY, Sep. 2016, Peer-reviewed

  
• Treatment With Pravastatin Decreases the Level of Serum Hs-CRP in Ischemic Stroke Patients-Hs-CRP Sub-study of the Japan Statin Treatment Against Recurrent Stroke (J-STARS)

  Kazuo Kitagawa; Naohisa Hosomi; Yoji Nagai; Tatsuo Kagimura; Hideki Origasa; Kazuo Minematsu; Shinichiro Uchiyama; Masakazu Nakamura; Masayasu Matsumoto

  STROKE, Feb. 2016, Peer-reviewed

  
• SURVIVAL OF CENTENARIANS IN JAPAN.

  Kenta Murotani; Bin Zhou; Hideaki Kaneda; Eiji Nakatani; Shinsuke Kojima; Yoji Nagai; Masanori Fukushima

  Journal of biosocial science, Nov. 2015, Peer-reviewed

  
• Pravastatin Treatment Is More Effective for Preventing Occurrence of Atherothrombotic Infarction When Started Within 6 Months after Initial Stroke: Post-Hoc Analysis of J-STARS

  N. Hosomi; Y. Nagai; S. Aoki; T. Nezu; K. Kitagawa; K. Minematsu; S. Uchiyama; M. Matsumoto

  CEREBROVASCULAR DISEASES, Oct. 2015

  
• The Japan Statin Treatment Against Recurrent Stroke (J-STARS): A Multicenter, Randomized, Open-label, Parallel-group Study.

  Naohisa Hosomi; Yoji Nagai; Tatsuo Kohriyama; Toshiho Ohtsuki; Shiro Aoki; Tomohisa Nezu; Hirofumi Maruyama; Norio Sunami; Chiaki Yokota; Kazuo Kitagawa; Yasuo Terayama; Makoto Takagi; Setsuro Ibayashi; Masakazu Nakamura; Hideki Origasa; Masanori Fukushima; Etsuro Mori; Kazuo Minematsu; Shinichiro Uchiyama; Yukito Shinohara; Takenori Yamaguchi; Masayasu Matsumoto

  EBioMedicine, Sep. 2015, Peer-reviewed

  
• Temporal and regional variations in sporadic Creutzfeldt-Jakob disease in Japan, 2001-2010.

  E Nakatani; T Nishimura; B Zhou; H Kaneda; S Teramukai; Y Nagai; M Fukushima; Y Kanatani

  Epidemiology and infection, Apr. 2015, Peer-reviewed

  
• Final results of cilostazol-aspirin therapy against recurrent stroke with intracranial artery stenosis (CATHARSIS)

  Shinichiro Uchiyama; Nobuyuki Sakai; Sono Toi; Masayuki Ezura; Yasushi Okada; Makoto Takagi; Yoji Nagai; Yoshihiro Matsubara; Kazuo Minematsu; Norihiro Suzuki; Norio Tanahashi; Waro Taki; Izumi Nagata; Masayasu Matsumoto

  Cerebrovascular Diseases Extra, 2015, Peer-reviewed

  
• Rationale, design, and baseline features of a randomized controlled trial to assess the effects of statin for the secondary prevention of stroke: the Japan Statin Treatment Against Recurrent Stroke (J-STARS).

  Yoji Nagai; Tatsuo Kohriyama; Hideki Origasa; Kazuo Minematsu; Chiaki Yokota; Shinichiro Uchiyama; Setsuro Ibayashi; Yasuo Terayama; Makoto Takagi; Kazuo Kitagawa; Eiichi Nomura; Naohisa Hosomi; Toshiho Ohtsuki; Takemori Yamawaki; Yoshihiro Matsubara; Masakazu Nakamura; Yoshimitsu Yamasaki; Etsuro Mori; Masanori Fukushima; Shotai Kobayashi; Yukito Shinohara; Takenori Yamaguchi; Masayasu Matsumoto

  International journal of stroke : official journal of the International Stroke Society, Feb. 2014, Peer-reviewed

  
• Recent trends in neuroendovascular therapy in Japan: analysis of a nationwide survey--Japanese Registry of Neuroendovascular Therapy (JR-NET) 1 and 2.

  Nobuyuki Sakai; Shinichi Yoshimura; Waro Taki; Akio Hyodo; Shigeru Miyachi; Yoji Nagai; Chiaki Sakai; Tetsu Satow; Tomoaki Terada; Masayuki Ezura; Toshio Hyogo; Shunji Matsubara; Kentaro Hayashi; Toshiyuki Fujinaka; Yasushi Ito; Shigeki Kobayashi; Masaki Komiyama; Naoya Kuwayama; Yuji Matsumaru; Yasushi Matsumoto; Yuichi Murayama; Ichiro Nakahara; Shigeru Nemoto; Koichi Satoh; Kenji Sugiu; Akira Ishii; Hirotoshi Imamura

  Neurologia medico-chirurgica, 2014, Peer-reviewed

  
• Recent trends in neuroendovascular therapy in Japan: analysis of a nationwide survey--Japanese Registry of Neuroendovascular Therapy (JR-NET) 1 and 2.

  Nobuyuki Sakai; Shinichi Yoshimura; Waro Taki; Akio Hyodo; Shigeru Miyachi; Yoji Nagai; Chiaki Sakai; Tetsu Satow; Tomoaki Terada; Masayuki Ezura; Toshio Hyogo; Shunji Matsubara; Kentaro Hayashi; Toshiyuki Fujinaka; Yasushi Ito; Shigeki Kobayashi; Masaki Komiyama; Naoya Kuwayama; Yuji Matsumaru; Yasushi Matsumoto; Yuichi Murayama; Ichiro Nakahara; Shigeru Nemoto; Koichi Satoh; Kenji Sugiu; Akira Ishii; Hirotoshi Imamura

  Neurologia medico-chirurgica, 2014, Peer-reviewed

  
• Association between abnormal myocardial fatty acid metabolism and cardiac-derived death among patients undergoing hemodialysis: results from a cohort study in Japan.

  Masao Moroi; Nagara Tamaki; Masato Nishimura; Kazuo Haze; Tsunehiko Nishimura; Eiji Kusano; Takashi Akiba; Tokuichiro Sugimoto; Hiroki Hase; Kazuhiro Hara; Tomoaki Nakata; Shinichiro Kumita; Yoji Nagai; Akiyoshi Hashimoto; Mitsuru Momose; Keiko Miyakoda; Naoyuki Hasebe; Kenjiro Kikuchi

  American journal of kidney diseases : the official journal of the National Kidney Foundation, Mar. 2013, Peer-reviewed

  
• Final Results of Cilostazol-Aspirin Therapy Against Recurrent Stroke with Intracranial Artery Stenosis (CATHARSIS)

  Shinichiro Uchiyama; Nobuyuki Sakai; Sono Toi; Masayuki Ezura; Yasushi Okada; Makoto Takagi; Yoji Nagai; Keiko Miyakoda; Kazuo Minematsu; Norihiro Suzuki; Norio Tanahashi; Waro Taki; Izumi Nagata; Masayasu Matsumoto

  STROKE, Feb. 2013, Peer-reviewed

  
• Risk classification in mild cognitive impairment patients for developing Alzheimer's disease.

  Bin Zhou; Eiji Nakatani; Satoshi Teramukai; Yoji Nagai; Masanori Fukushima

  Journal of Alzheimer's disease : JAD, 2012, Peer-reviewed

  
• Regenerative medicine in critical limb ischemia.

  Takayuki Ohno; Hideaki Kaneda; Yoji Nagai; Masanori Fukushima

  Journal of atherosclerosis and thrombosis, 2012, Peer-reviewed

  
• 医師主導治験実施計画書テンプレートの開発

  古川 恵子; 手良向 聡; 黒中 香織; 松山 琴音; 柏木 直子; 都田 桂子; 大野 隆之; 野口 雄次; 永井 洋士; 福島 雅典

  臨床薬理, Oct. 2011, Peer-reviewed

  
• Analysis of baseline data on the Cilostazol-Aspirin Therapy Against Recurrent Stroke with Intracranial Artery Stenosis (CATHARSIS)

  Shinichiro Uchiyama; Nobuyuki Sakai; Makoto Takagi; Kazuo Minematsu; Masayuki Ezura; Yasushi Okada; Yoji Nagai

  STROKE, Mar. 2011, Peer-reviewed

  
• Characterization of conditioned medium of cultured bone marrow stromal cells.

  Norihiko Nakano; Yoshiyasu Nakai; Tae-Boem Seo; Yoshihiro Yamada; Takayuki Ohno; Atsuo Yamanaka; Yoji Nagai; Masanori Fukushima; Yoshiyuki Suzuki; Toshio Nakatani; Chizuka Ide

  Neuroscience letters, 08 Oct. 2010, Peer-reviewed

  
• The current situation and challenges with management of clinical studies supported by Translational Research Informatics Center

  Kotone Matsuyama; Takayuki Ohno; Yoji Nagai; Masanori Fukushima

  Japanese Pharmacology and Therapeutics, 30 Jul. 2010, Peer-reviewed

  
• Modified Enrichment Method for Identification of Human Cerebrospinal Fluid Proteins by Mass Spectrometry

  Bin Zhou; Yoshinori Tanaka; Akira Matsumoto; Hideo Akiyama; Yoji Nagai; Masanori Fukushima

  CURRENT PROTEOMICS, Oct. 2009, Peer-reviewed

  
• Prospective evaluation of whole-body cancer screening with multiple modalities including [18F]fluorodeoxyglucose positron emission tomography in a healthy population: a preliminary report.

  Sadahiko Nishizawa; Shinsuke Kojima; Satoshi Teramukai; Masayuki Inubushi; Hironobu Kodama; Yoshiki Maeda; Hiroyuki Okada; Bin Zhou; Yoji Nagai; Masanori Fukushima

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 10 Apr. 2009, Peer-reviewed

  
• Prognostic study of cardiac events in Japanese high risk hemodialysis patients using I-BMIPP-SPECT: B-SAFE study design.

  Naoyuki Hasebe; Masao Moroi; Masato Nishimura; Kazuhiro Hara; Hiroki Hase; Akiyoshi Hashimoto; Shinichiro Kumita; Kazuo Haze; Mitsuru Momose; Yoji Nagai; Tokuichiro Sugimoto; Eiji Kusano; Takashi Akiba; Tomoaki Nakata; Tsunehiko Nishimura; Nagara Tamaki; Kenjiro Kikuchi

  Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, Dec. 2008, Peer-reviewed

  
• Safety evaluation of oral fluoropyrimidine S-1 for short- and long-term delivery in advanced gastric cancer: analysis of 3,758 patients.

  Takeharu Yamanaka; Shigemi Matsumoto; Satoshi Teramukai; Ryota Ishiwata; Yoji Nagai; Masanori Fukushima

  Cancer chemotherapy and pharmacology, Feb. 2008, Peer-reviewed

  
• Predictive value of chemotherapy-induced neutropenia for the efficacy of oral fluoropyrimidine S-1 in advanced gastric carcinoma.

  T Yamanaka; S Matsumoto; S Teramukai; R Ishiwata; Y Nagai; M Fukushima

  British journal of cancer, 02 Jul. 2007, Peer-reviewed

  
• 【癌臨床試験を支援する機構のあり方】臨床試験の支援のしくみとあり方

  福島 雅典; 永井 洋士; 手良向 聡; 平尾 佳彦

  癌の臨床, Apr. 2007, Peer-reviewed

  
• 【癌臨床試験を支援する機構のあり方】臨床研究情報センター(TRI)の役割と活動

  松山 琴音; 永井 洋士; 手良向 聡; 福島 雅典; 村上 雅義

  癌の臨床, Apr. 2007, Peer-reviewed

  
• Carotid intima-media thickness and risk of cardiovascular events in high-risk patients. Results of the Osaka Follow-Up Study for Carotid Atherosclerosis 2 (OSACA2 Study).

  Kazuo Kitagawa; Hidetaka Hougaku; Hiroshi Yamagami; Hiroyuki Hashimoto; Taiji Itoh; Yoshiomi Shimizu; Daisuke Takahashi; Shinji Murata; Yujiro Seike; Kimito Kondo; Taku Hoshi; Shigetaka Furukado; Yuko Abe; Yoshiki Yagita; Manabu Sakaguchi; Masafumi Tagaya; Hideki Etani; Ryuzo Fukunaga; Yoji Nagai; Masayasu Matsumoto; Masatsugu Hori

  Cerebrovascular diseases (Basel, Switzerland), 2007, Peer-reviewed

  
• Analysis of risk factors for severe adverse effects of oral 5-fluorouracil S-1 in patients with advanced gastric cancer.

  Takeharu Yamanaka; Shigemi Matsumoto; Satoshi Teramukai; Ryota Ishiwata; Yoji Nagai; Masanori Fukushima

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2007, Peer-reviewed

  
• The baseline ratio of neutrophils to lymphocytes is associated with patient prognosis in advanced gastric cancer.

  Takeharu Yamanaka; Shigemi Matsumoto; Satoshi Teramukai; Ryota Ishiwata; Yoji Nagai; Masanori Fukushima

  Oncology, 2007, Peer-reviewed

  
• Associations of serum IL-18 levels with carotid intima-media thickness.

  Hiroshi Yamagami; Kazuo Kitagawa; Taku Hoshi; Shigetaka Furukado; Hidetaka Hougaku; Yoji Nagai; Masatsugu Hori

  Arteriosclerosis, thrombosis, and vascular biology, Jul. 2005, Peer-reviewed

  
• Associations of soluble intercellular adhesion molecule-1 with carotid atherosclerosis progression.

  Kimito Kondo; Kazuo Kitagawa; Yoji Nagai; Hiroshi Yamagami; Hiroyuki Hashimoto; Hidetaka Hougaku; Masatsugu Hori

  Atherosclerosis, Mar. 2005, Peer-reviewed

  
• Infrastructure of clinical trials/studies-Role of Translational Research Informatics Center-:Role of Translational Research Informatics Center

  Nagai Yoji; Fukushima Masanori

  Jpn. J. Stroke, 2005

  
• Higher levels of interleukin-6 are associated with lower echogenicity of carotid artery plaques.

  Hiroshi Yamagami; Kazuo Kitagawa; Yoji Nagai; Hidetaka Hougaku; Manabu Sakaguchi; Keisuke Kuwabara; Kimito Kondo; Tohru Masuyama; Masayasu Matsumoto; Masatsugu Hori

  Stroke, Mar. 2004, Peer-reviewed

  
• 医療技術評価の基盤としての大規模疾患登録・追跡システムの構築

  手良向 聡; 木村 剛; 永井 洋士; 井上 智夫; 福島 雅典

  医療情報学連合大会論文集, Nov. 2003, Peer-reviewed

  
• Effects of aldehyde dehydrogenase genotypes on carotid atherosclerosis.

  Masako Narita; Kazuo Kitagawa; Yoji Nagai; Hidetaka Hougaku; Hiroyuki Hashimoto; Manabu Sakaguchi; Xing Yang; Tatsuya Takeshita; Kanehisa Morimoto; Masayasu Matsumoto; Masatsugu Hori

  Ultrasound in medicine & biology, Oct. 2003, Peer-reviewed

  
• Mechanical compression of the extracranial vertebral artery during neck rotation.

  M Sakaguchi; K Kitagawa; H Hougaku; H Hashimoto; Y Nagai; H Yamagami; T Ohtsuki; N Oku; K Hashikawa; K Matsushita; M Matsumoto; M Hori

  Neurology, 23 Sep. 2003, Peer-reviewed

  
• Carotid atherosclerosis as a risk factor for complex aortic lesions in patients with ischemic cerebrovascular disease.

  Yoshiomi Shimizu; Kazuo Kitagawa; Yoji Nagai; Masako Narita; Hidetaka Hougaku; Tohru Masuyama; Masayasu Matsumoto; Masatsugu Hori

  Circulation journal : official journal of the Japanese Circulation Society, Jul. 2003, Peer-reviewed

  
• Equivalence of plaque score and intima-media thickness of carotid ultrasonography for predicting severe coronary artery lesion.

  Manabu Sakaguchi; Kazuo Kitagawa; Yoji Nagai; Hiroshi Yamagami; Kimito Kondo; Kohji Matsushita; Naohiko Oku; Hidetaka Hougaku; Toshiho Ohtsuki; Tohru Masuyama; Masayasu Matsumoto; Masatsugu Hori

  Ultrasound in medicine & biology, Mar. 2003, Peer-reviewed

  
• Implication of earlier carotid atherosclerosis for stroke and its subtypes.

  Yoji Nagai; Kazuo Kitagawa; Masayasu Matsumoto

  Preventive cardiology, 2003, Peer-reviewed

  
• The carotid artery as a noninvasive window for cardiovascular risk in apparently healthy individuals.

  Yoji Nagai; Masayasu Matsumoto; E Jeffrey Metter

  Ultrasound in medicine & biology, Oct. 2002, Peer-reviewed

  
• Carotid artery intima-media thickness and plaque score for the risk assessment of stroke subtypes.

  Yoji Nagai; Kazuo Kitagawa; Hiroshi Yamagami; Kimito Kondo; Hidetaka Hougaku; Masatsugu Hori; Masayasu Matsumoto

  Ultrasound in medicine & biology, Oct. 2002, Peer-reviewed

  
• Carotid atherosclerosis as a predictor for complex aortic lesions in patients with ischemic cerebrovascular disease

  Y Shimizu; K Kitagawa; Y Nagai; M Narita; H Hougaku; T Masuyama; M Matsumoto; M Hori

  JOURNAL OF HYPERTENSION, Jun. 2002, Peer-reviewed

  
• Association of plasma homocysteine concentration with atherosclerotic carotid plaques and lacunar infarction.

  Tsutomu Sasaki; Manabu Watanabe; Yoji Nagai; Taku Hoshi; Masashi Takasawa; Masaru Nukata; Akihiko Taguchi; Kazuo Kitagawa; Naokazu Kinoshita; Masayasu Matsumoto

  Stroke, Jun. 2002, Peer-reviewed

  
• Smoking habit as a putative risk factor for carotid plaque ulcers

  Osamu Iiji; Yoji Nagai; Taiji Itoh; Hidetaka Hougaku; Kazuo Kitagawa; Masatsugu Hori; Masayasu Matsumoto

  Journal of Stroke and Cerebrovascular Diseases, 2002, Peer-reviewed

  
• Associations of aortic Windkessel function with age, gender and cardiovascular risk factors.

  Y Nagai; J Helwegen; J L Fleg; M K Beemer; C J Earley; E J Metter

  Ultrasound in medicine & biology, Sep. 2001, Peer-reviewed

  
• Significance of earlier carotid atherosclerosis for stroke subtypes.

  Y Nagai; K Kitagawa; M Sakaguchi; Y Shimizu; H Hashimoto; H Yamagami; M Narita; T Ohtsuki; M Hori; M Matsumoto

  Stroke, Aug. 2001, Peer-reviewed

  
• C-reactive protein is an independent predictor of the rate of increase in early carotid atherosclerosis.

  H Hashimoto; K Kitagawa; H Hougaku; Y Shimizu; M Sakaguchi; Y Nagai; S Iyama; H Yamanishi; M Matsumoto; M Hori

  Circulation, 03 Jul. 2001, Peer-reviewed

  
• Clinical usefulness of duplex ultrasonography for the assessment of renal arteriosclerosis in essential hypertensive patients.

  Y Shimizu; T Itoh; H Hougaku; Y Nagai; H Hashimoto; M Sakaguchi; N Handa; K Kitagawa; M Matsumoto; M Hori

  Hypertension research : official journal of the Japanese Society of Hypertension, Jan. 2001, Peer-reviewed

  
• Implication of early carotid atherosclerosis for stroke subtypes

  Y Nagai; M Matsumoto; H Yamagami; Y Shimizu; M Sakaguchi; H Hashimoto; K Kitagawa; M Hori

  STROKE, Nov. 2000, Peer-reviewed

  
• Decay Index: a new carotid Doppler waveform measure associated with the Windkessel function of elastic arteries.

  Y Nagai; J Helwegen; J L Fleg; M K Kemper; C J Earley; T M Rywik; P Wijn; E J Metter

  Ultrasound in medicine & biology, Nov. 1999, Peer-reviewed

  
• Carotid arterial stiffness as a surrogate for aortic stiffness: relationship between carotid artery pressure-strain elastic modulus and aortic pulse wave velocity.

  Y Nagai; J L Fleg; M K Kemper; T M Rywik; C J Earley; E J Metter

  Ultrasound in medicine & biology, Feb. 1999, Peer-reviewed

  
• Influence of age and postmenopausal estrogen replacement therapy on carotid arterial stiffness in women.

  Y Nagai; C J Earley; M K Kemper; C S Bacal; E J Metter

  Cardiovascular research, Jan. 1999, Peer-reviewed

  
• Increased carotid artery intimal-medial thickness: risk factor for exercise-induced myocardial ischemia in asymptomatic older individuals.

  Y Nagai; E J Metter; J L Fleg

  Vascular medicine (London, England), 1999, Peer-reviewed

  
• Increased carotid artery intimal-medial thickness in asymptomatic older subjects with exercise-induced myocardial ischemia.

  Y Nagai; E J Metter; C J Earley; M K Kemper; L C Becker; E G Lakatta; J L Fleg

  Circulation, 13 Oct. 1998, Peer-reviewed

  
• Blood-flow velocities and their relationships in carotid and middle cerebral arteries.

  Y Nagai; M K Kemper; C J Earley; E J Metter

  Ultrasound in medicine & biology, Oct. 1998, Peer-reviewed

  

Misc.

• Cognitive Function Instrument(CFI)日本語版の信頼性・妥当性に関する中間解析

  尾嵜 遠見; 山本 泰司; 永井 洋士; 古和 久朋; 小島 伸介; 菊池 隆; 梶田 博之; 前田 潔

  Dementia Japan, Oct. 2019

  
• 神戸市の高齢者を対象とした要介護認定のリスクの予測に関する前向きコホート研究

  小島 伸介; 菊池 隆; 永井 洋士; 古和 久朋; 山本 泰司; 梶田 博之; 尾嵜 遠見; Kothari Kavita; 茅野 龍馬

  日本老年医学会雑誌, May 2021

  
• 【ここまで進んだ先端医療】アカデミアのR&Dパイプラインの確立とTRネットワーク形成

  福島 雅典; 大野 隆之; 松山 琴音; 永井 洋士

  臨牀と研究, Apr. 2011

  
• わが国における大規模臨床試験の振興について

  福島 雅典; 大野 隆之; 松山 琴音; 小島 伸介; 永井 洋士

  臨床評価, Mar. 2011

  
• 研究者主導臨床試験の支援をどうするか 臨床研究情報センター(TRI)における臨床研究支援の現状と課題

  松山 琴音; 大野 隆之; 永井 洋士; 福島 雅典

  薬理と治療, Jul. 2010

  
• 守る会助成課題 小児がん治療ガイドラインおよび小児がん治療成績のインターネット配信実現に係る研究

  松山 琴音; 小野寺 理恵; 細井 創; 家原 知子; 永井 洋士; 福島 雅典

  小児がん, Nov. 2008

  
• J-STARS試験に登録された脳梗塞患者1000例の臨床的特徴

  松本 昌泰; 郡山 達男; 橋田 寿美; 大槻 俊輔; 野村 栄一; 永井 洋士; 松山 琴音

  臨床神経学, Dec. 2007

  
• 小児がん治療ガイドラインおよび小児がん治療成績のインターネット配信実現に係る研究

  松山 琴音; 小野寺 理恵; 細井 創; 家原 知子; 永井 洋士; 福島 雅典

  小児がん, Dec. 2007

  
• J-STARS試験登録症例の臨床的特徴 1000症例登録時点での解析

  松本 昌泰; 郡山 達男; 橋田 寿美; 永井 洋士; 松山 琴音; 峰松 一夫; 横田 千晶; 折笠 秀樹; 内山 真一郎; 井林 雪郎

  脳卒中, Mar. 2007

  
• 小児がん治療ガイドラインおよび小児がん治療成績のインターネット配信実現に係る研究

  松山 琴音; 細井 創; 家原 知子; 永井 洋士; 福島 雅典

  日本小児血液学会雑誌, Oct. 2006

  
• 脳卒中の大規模調査 脳卒中大規模臨床試験(J-STARS)をモデルとした電子的臨床データ収集基盤の構築

  永井 洋士; 松山 琴音; 高原 志津子; 橋田 寿美; 郡山 達男; 松本 昌泰

  脳卒中, Mar. 2006

  
• 脳血管疾患の再発に対するスタチンの予防効果に関する大規模臨床試験の実施体制整備

  橋田 寿美; 郡山 達男; 児玉 仁美; 住田 裕美; 野村 栄一; 山下 拓史; 大槻 俊輔; 松山 琴音; 永井 洋士; 松本 昌泰

  脳卒中, Mar. 2006

  
• Construction of electronic data capture and its facilitating systems for a large scale clinical trial model

  NAGAI Yoji; MATSUYAMA Kotone; TAKAHARA Shizuko; HASHIDA Hisami; KOHRIYAMA Tatsuo; MATSUMOTO Masayasu

  脳卒中, 25 Dec. 2006

  
• 低コストかつ効率的な臨床研究データ遠隔収集システムの構築

  黒木 慎也; 多田 春江; 山本 景一; 石戸 是亘; 菅田 勝文; 岸本 容司; 天辰 香織; 楠 康代; 松山 琴音; 小島 伸介; 手良向 聡; 永井 洋士; 福島 雅典

  医療情報学連合大会論文集, Oct. 2006

  
• 24OP15-13 小児がん治療ガイドラインおよび小児がん治療成績のインターネット配信実現に係る研究(ポスター がんの子供を守る会助成課題,第22回日本小児がん学会 第48回日本小児血液学会 第4回日本小児がん看護研究会 同時期開催)

  松山 琴音; 細井 創; 家原 知子; 永井 洋士; 福島 雅典

  小児がん : 小児悪性腫瘍研究会記録, 2006

  
• トランスレーショナルリサーチ実施にあたっての共通倫理審査指針

  浅野 茂隆; 岩本 愛吉; 田原 秀晃; 大島 伸一; 吉田 純; 直江 知樹; 金倉 譲; 澤 芳樹; 橋爪 誠; 中西 洋一; 村上 雅義; 永井 洋士; 小田 英世; 田中 紘一; 清水 章; 横出 正之; 手良向 聡; 福島 雅典

  臨床評価, Apr. 2004

  
• 質の高い臨床試験を計画・実施するためのプロトコルテンプレートの開発

  古川 恵子; 手良向 聡; 岡 昌子; 松山 琴音; 黒中 香織; 荒田 さおり; 都田 桂子; 大野 隆之; 松山 晃文; 永井 洋士; 福島 雅典

  臨床薬理, Nov. 2010

  
• 癌臨床試験を支援する機構のあり方 臨床研究情報センター(TRI)の役割

  松山 琴音; 永井 洋士; 稲岡 正子; 手良向 聡; 松井 茂之; 福島 雅典; 村上 雅義

  日本癌治療学会誌, Sep. 2006

  
• 医師主導臨床試験「J-STARS」におけるWeb症例登録・追跡システム

  松山 琴音; 永井 洋士; 山本 景一; 高橋 繁利; 原田 智佳子; 手良向 聡; 橋田 寿美; 児玉 仁美; 野村 栄一; 中村 克人; 郡山 達男; 松本 昌泰; 福島 雅典

  医療情報学連合大会論文集, Nov. 2005

  
• 臨床研究実施計画書作成支援システム「スタディデザイナー」の開発

  楠 康代; 江口 直樹; 小島 伸介; 大門 貴志; 多田 春江; 津村 はやみ; 手良向 聡; 永井 洋士; 福島 雅典; 藤井 由佳; 松山 晶子

  医療情報学連合大会論文集, Nov. 2005

  
• 医師主導がん臨床試験における症例報告書の作成支援

  荒田 さおり; 松山 琴音; 小野寺 理恵; 須子 靖子; 津村 はやみ; 貞池 哲志; 松山 晶子; 多田 春江; 村田 桂子; 大門 貴志; 小田 英世; 手良向 聡; 永井 洋士; 福島 雅典; 古瀬 清行

  臨床薬理, Jan. 2004

  
• 医師主導臨床研究における薬剤管理業務の現状と課題

  松山 琴音; 荒田 さおり; 小野寺 理恵; 貞池 哲志; 松山 晶子; 津村 はやみ; 須子 靖子; 村田 桂子; 多田 春江; 小田 英世; 永井 洋士; 手良向 聡; 福島 雅典; 古瀬 清行

  臨床薬理, Jan. 2004

  
• Flaws of clinical trial system in Japan, and what needs to be changed for the maximization of public welfare

  永井 洋士; 中谷 英仁; 河野 健一

  腫瘍内科 = Clinical oncology, Jul. 2015, Invited

  
• Present Status of J-STARS and Substudies

  Masayasu Matsumoto; Naohisa Hosomi; Shiro Aoki; Masanori Fukushima; Yoji Nagai; Kazuo Minematsu; Chiaki Yokota; Hideki Origasa; Shinichiro Uchiyama; Setsuro Ibayashi

  CEREBROVASCULAR DISEASES, Sep. 2014

  
• Present Status of J-STARS and Substudies

  Masayasu Matsumoto; Takemori Yamawaki; Toshiho Ohtsuki; Naohisa Hosomi; Masanori Fukushima; Yoji Nagai; Kazuo Minematsu; Chiaki Yokota; Hideki Origasa; Shinichiro Uchiyama; Setsuro Ibayashi

  CEREBROVASCULAR DISEASES, 2012

  

Presentations

• 診療科モニタリングを支える補助ツールとしてのファイリングシステムの導入

  小谷 保之; 鳥越 奈穂; 石田 裕紀; 山崎 純子; 柏木 直子; 五百蔵 武士; 久米 学; Omori Takashi; Nagai Yoji

  日本臨床試験学会第9回学術集会総会, Feb. 2018, 日本臨床試験学会

  
• 『プロトコールの煩雑さ』を可視化するTool for Operational Protocol Scoring(TOPS)についての検討

  山崎 純子; 五百蔵 武士; 久米 学; 石田 裕紀; 北村 直子; 立花 せり; 梶川 清香; 坂井 あゆみ; 野口 裕加; Nagai Yoji

  第17回 CRCと臨床試験のあり方を考える会議, Sep. 2017, CRCと臨床試験のあり方を考える会議

  
• 症例報告書を再構築できる原データの品質管理に対する取り組み

  北村 直子; 山﨑 純子; 小谷 真基; 石田 裕紀; 芝 円; 森谷 友美; 梶川 清香; 久米 学; Hirai Midori; Nagai Yoji

  第16回CRCと臨床試験のあり方を考える会議, Sep. 2016, 臨床試験支援財団

  
• Present Status of J-STARS and Substudies

  Masayasu Matsumoto; Naohisa Hosomi; Shiro Aoki; Masanori Fukushima; Yoji Nagai; Kazuo Minematsu; Chiaki Yokota; Hideki Origasa; Shinichiro Uchiyama; Setsuro Ibayashi

  CEREBROVASCULAR DISEASES, Sep. 2014, KARGER

  
• Present Status of J-STARS and Substudies

  Masayasu Matsumoto; Takemori Yamawaki; Toshiho Ohtsuki; Naohisa Hosomi; Masanori Fukushima; Yoji Nagai; Kazuo Minematsu; Chiaki Yokota; Hideki Origasa; Shinichiro Uchiyama; Setsuro Ibayashi

  CEREBROVASCULAR DISEASES, 2012, KARGER

  

Education

Teaching subject(s)

• From 01 Apr. 2024, To 31 Mar. 2025

  Translational & Clinical Research Management

  E068, Year-long, Graduate School of Medicine, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Translational & Clinical Research Management

  E068, Year-long, Graduate School of Medicine, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Translational & Clinical Research Management

  E068, Year-long, Graduate School of Medicine, 2

Participation in PhD Defense

• Effectiveness of Reduced-fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy:A Propensity Score Analysis

  AISU NAO, Graduate School of Medicine, Sub-chief Examiner

  25 Mar. 2024
• Reoperation Rates of Microendoscopic Discectomy Compared With Conventional Open Lumbar Discectomy: A Large-database Study

  MASUDA SOICHIRO, Graduate School of Medicine, Sub-chief Examiner

  25 Mar. 2024
• Dealing with missing data in laboratory test results used as a baseline covariate: results of multi-hospital cohort studies utilizing a database system contributing to MID-NETR in Japan

  SAKURAI MAKI, Graduate School of Medicine, Sub-chief Examiner

  25 Mar. 2024
• Determining the late effect parameter in the Fleming-Harrington test using asymptotic relative efficiency in cancer immunotherapy clinical trials

  KANEKO YUICHIRO, Graduate School of Medicine, Sub-chief Examiner

  23 Jan. 2024
• Lack of association between seropositivity of vasculopathy-related viruses and moyamoya disease

  NAKAMURA YASUHISA, Graduate School of Medicine, Sub-chief Examiner

  23 May 2023
• Electronic Health Record-Nested Reminders for Serum Lithium Level Monitoring in Patients With Mood Disorder: Randomized Controlled Trial

  SEKI TOMOTSUGU, Graduate School of Medicine, Sub-chief Examiner

  25 Mar. 2024
• Association of Cortical Superficial Siderosis with Post-Stroke Epilepsy

  TANAKA TOMOTAKA, Graduate School of Medicine, Sub-chief Examiner

  23 May 2023
• The importance of central airway dilatation in patients with bronchiolitis obliterans

  KOGO MARIKO, Graduate School of Medicine, Chief Examiner

  23 Mar. 2023
• Percutaneous Coronary Intervention Versus Coronary Artery Bypass Graftinge Among Patients with Unprotected Left Main Coronary Artery Disease in the New-Generation Drug-Eluting Stents Era (From the CREDO-Kyoto PCI/CABG Registry Cohort-3)

  YAMAMOTO KO, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2023
• Two-Minute Quantitative Susceptibility Mapping From Three-Dimensional Echo-Planar Imaging Accuracy, Reliability, and Detection Performance in Patients With Cerebral Microbleeds

  KRISHNA PANDU WICAKSONO, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2023
• KUS121, a valosin-containing protein modulator, attenuates ischemic stroke via preventing ATP depletion

  KINOSHITA HISANORI, Graduate School of Medicine, Chief Examiner

  23 Jan. 2023
• Effectiveness and safety of a program for appropriate urinary catheter use in stroke care: A multicenter prospective study

  IKEDA YASUKO, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2022
• Development and validation of early prediction for neurological outcome at 90 days after return of spontaneous circulation in out-of-hospital cardiac arrest

  NISHIOKA NORIHIRO, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2022
• Niclosamide downregulates LOX-1 expression in mouse vascular smooth muscle cell and changes the composition of atherosclerotic plaques in ApoE-/- mice

  YANG TAO, Graduate School of Medicine, Chief Examiner

  23 Mar. 2022
• Lists of potential diagnoses that final-year medical students need to consider: a modified Delphi study

  MIYACHI YUKA, Graduate School of Medicine, Sub-chief Examiner

  24 Jan. 2022

Administration

School management (title, position)

• From 01 Apr. 2024, To 31 Mar. 2025

  病院協議会

Faculty management (title, position)

• From 01 Apr. 2022, To 31 Mar. 2023

  病院協議会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  細胞療法センター運営委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  細胞療法センターコア会議　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  先端医療研究開発機構協議会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  先端医療研究開発機構執行部会議　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  先端医療研究開発機構財務委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  先端医療研究開発機構人事委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  先端医療研究開発機構推進委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  先端医療研究開発機構ACTION-K推進委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  先端医療研究開発機構支援研究検討・管理会議　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  先端医療研究開発機構 次世代医療iPS細胞研究センター運営委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  倫理支援部運営委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  先進医療・患者申出療養専門委員会　委員長
• From 01 Apr. 2022, To 31 Mar. 2023

  医療安全管理委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  臨床研究安全管理小委員会　委員長
• From 01 Apr. 2022, To 31 Mar. 2023

  未承認新規医薬品等評価委員会
• From 01 Apr. 2022, To 31 Mar. 2023

  医薬品等臨床研究審査委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  特定臨床研究等実施管理委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  研究開発戦略推進委員会　委員
• From 01 Apr. 2022, To 31 Mar. 2023

  　
• From 01 Apr. 2022, To 31 Mar. 2023

  シーズ選定評価委員会　委員