Basic Information

Academic Degree

• 修士（生命科学）(東洋大学)
• 博士（生命科学）(東洋大学)

Research History

• Toyo University, 研究助手

ID,URL

• J-Global ID

  201301007351458211

• Researcher number

  60625391

researchmap URL

• https://researchmap.jp/g0000211163

Research

Research Areas

• Nanotechnology/Materials, Nanobioscience

Papers

• Tumor Targeting and Tumor Growth Inhibition Capability of Mesoporous Silica Nanoparticles in Mouse Models

  Tan Le Hoang Doan; Ngoc Xuan Dat Mai; Kotaro Matsumoto; Fuyuhiko Tamanoi

  Enzymes, 01 Jan. 2018

  
• Anticancer Drug Delivery Capability of Biodegradable PMO in the Chicken Egg Tumor Model

  Kotaro Matsumoto; Tan Le Hoang Doan; Ngoc Xuan Dat Mai; Keigo Nakai; Aoi Komatsu; Fuyuhiko Tamanoi

  Enzymes, 01 Jan. 2018

  
• Organosilica nanoparticles containing sodium borocaptate (BSH) provide new prospects for boron neutron capture therapy (BNCT): efficient cellular uptake and enhanced BNCT efficacy.

  Mathilde Laird; Kotaro Matsumoto; Yuya Higashi; Aoi Komatsu; Art Raitano; Kendall Morrison; Minoru Suzuki; Fuyuhiko Tamanoi

  Nanoscale advances, 02 May 2023

  Access this paper :

  
• Tumor Accumulation of PIP-Based KRAS Inhibitor KR12 Evaluated by the Use of a Simple, Versatile Chicken Egg Tumor Model

  Yuya Higashi; Shuji Ikeda; Kotaro Matsumoto; Shinsuke Satoh; Aoi Komatsu; Hiroshi Sugiyama; Fuyuhiko Tamanoi

  Cancers, 14 Feb. 2022, Peer-reviewed

  
• The CAM Model for CIC-DUX4 Sarcoma and Its Potential Use for Precision Medicine

  Aoi Komatsu; Kotaro Matsumoto; Yuki Yoshimatsu; Yooksil Sin; Arisa Kubota; Tomoki Saito; Ayaka Mizumoto; Shinya Ohashi; Manabu Muto; Rei Noguchi; Tadashi Kondo; Fuyuhiko Tamanoi

  Cells, 01 Oct. 2021, Peer-reviewed

  
• Iodine containing porous organosilica nanoparticles trigger tumor spheroids destruction upon monochromatic X-ray irradiation: DNA breaks and K-edge energy X-ray

  Yuya Higashi; Kotaro Matsumoto; Hiroyuki Saitoh; Ayumi Shiro; Yue Ma; Mathilde Laird; Shanmugavel Chinnathambi; Albane Birault; Tan Le Hoang Doan; Ryo Yasuda; Toshiki Tajima; Tetsuya Kawachi; Fuyuhiko Tamanoi

  Scientific Reports, Dec. 2021, Peer-reviewed

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• Construction of boronphenylalanine-loaded biodegradable periodic mesoporous organosilica nanoparticles for BNCT cancer therapy

  Fuyuhiko Tamanoi; Shanmugavel Chinnathambi; Mathilde Laird; Aoi Komatsu; Albane Birault; Takushi Takata; Tan Le Hoang Doan; Ngoc Xuan Dat Mai; Arthur Raitano; Kendall Morrison; Minoru Suzuki; Kotaro Matsumoto

  International Journal of Molecular Sciences, Feb. 2021, Peer-reviewed, Last author

  
• Designing mesoporous silica nanoparticles to overcome biological barriers by incorporating targeting and endosomal escape

  Miguel Gisbert-Gazaran; Daniel Lozano; Kotaro Matsumoto; Aoi Komatsu; Miguel Manzano; Fuyuhiko Tamanoi; Maria Vallet-Regi

  ACS Applied Materials & Interfaces, Feb. 2021, Peer-reviewed

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• Studies on the exposure of Gadolinium containing nanoparticles with Monochromatic X-rays drive advances in radiation therapy

  Fuyuhiko Tamanoi; Kotaro Matsumoto; Tan Le Hoang Doan; Ayumi Shiro; Hiroyuki Saito

  Nanomaterials, Jul. 2020, Peer-reviewed

  
• Biodegradable periodic mesoporous organosilica (BPMO) loaded with Daunorubicin: A promising nanoparticle-based anticancer drug

  Ngoc Xuan; Dat Mai; Albane Birault; Kotaro Matsumoto; Hanh Kieu Thi Ta; Soontaree Grace Intasa-ard; Kendall Morrison; Phan Bach Thang; Tan Le Hoang Doan; Fuyuhiko Tamanoi

  ChemMedChem, Feb. 2020, Peer-reviewed

  
• Destruction of tumor mass by gadolinium-loaded nanoparticles irradiated with monochromatic X-rays: Implications for the Auger therapy

  Kotaro Matsumoto; Hiroyuki Saito; Tan Le-Hoang Doan; Ayumi Shiro; Keigo Nakai; Aoi Komatsu; Masahiko; Tsujimoto; Ryo Yasuda; Tetsuya Kawachi; Toshiki Tajima; Fuyuhiko Tamanoi

  Scientific reports, Sep. 2019, Peer-reviewed, Lead author

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• Patient Derived Chicken Egg Tumor Model (PDcE Model): Current Status and Critical Issues.

  Aoi Komatsu; Kotaro Matsumoto; Tomoki Saito; Manabu Muto; Fuyuhiko Tamanoi

  Cells, 10 May 2019, Peer-reviewed

  
• Chick chorioallantoic membrane assay as an in vivo model to study the effect of nanoparticle-based anticancer drugs in ovarian cancer.

  Binh Thanh Vu; Sophia Allaf Shahin; Jonas Croissant; Yevhen Fatieiev; Kotaro Matsumoto; Tan Le-Hoang Doan; Tammy Yik; Shirleen Simargi; Altagracia Conteras; Laura Ratliff; Chiara Mauriello Jimenez; Laurence Raehm; Niveen Khashab; Jean-Olivier Durand; Carlotta Glackin; Fuyuhiko Tamanoi

  Scientific reports, 04 Jun. 2018, Peer-reviewed

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Presentations

• Establishment of chicken chorioallantoic membrane (CAM) model and application to BNCT experiment using BPA-loaded silica nanoparticles

  Kotaro Matsumoto; Mathilde Laird; Aoi Komatsu; Shanmugavel Chinnathambi; Takushi Takata; Minoru Suzuki; Fuyuhiko Tamanoi

  The 17th Congress on Neutron Capture Therapy, 10 Jul. 2021

  
• Evaluation of novel nanoparticle-based anticancer drugs for cancer therapy by using ovarian cancer-transplanted chicken chorioallantoic membrane (CAM).

  Kotaro Matsumoto

  Proceedings of the 6th Japan-Chaina symposium on nanomedicine, 25 May 2018

  

Books and Other Publications

• Various CAM tumor models

  Aoi Komatsu; Yuya Higashi; Kotaro Matsumoto, Joint work

  The Enzymes, Oct. 2019

  
• がんの個別化医療を切り拓く鶏卵モデル

  玉野井冬彦; 遠藤良夫; 宇都義浩; 楠橋由貴; 二若真菜; 松本光太郎, Joint work

  実験医学, Jan. 2019

  
• Use of mesoporous silica nanoparticles to deliver anticancer agents in animal models.

  Kotaro Matsumoto, Joint work

  Elsevier, 2018, Not refereed

  
• Tumor targeting and tumor inhibition capability of biodegradable PMO as examined by using chicken egg tumor model

  Kotaro Matsumoto, Joint work

  Elsevier, 2018, Not refereed

  

External funds: Kakenhi

• がんAuger治療で放射線治療の低酸素問題解決を目指す

  Grant-in-Aid for Scientific Research (C)

  Basic Section 52040:Radiological sciences-related

  Kyoto University

  松本 光太郎

  From 01 Apr. 2024, To 31 Mar. 2027, Granted

  Auger電子;単色X線;ヨウ素含有Hoechst;低酸素状態の腫瘍;がんスフェロイド

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K10758/