Kuroda, Yusuke(Graduate School of Pharmaceutical Sciences) | Activity Database on Education and Research, Kyoto University

Kuroda, Yusuke

Graduate School of Pharmaceutical Sciences Program-Specific Assistant Professor

Last Updated :2025/06/02

Basic Information

Academic Degree

博士（薬科学）(京都大学)

修士（薬科学）(京都大学)

Research History

From Dec. 2021, To Present
卓越研究員

From Dec. 2021, To Present
京都大学白眉センター

From Dec. 2021, To Present
Kyoto University, Graduate School of Pharmaceutical Sciences, Program-Specific Assistant Professor (

From Dec. 2019, To Nov. 2021
Research Foundation ITSUU Laboratory, Researcher

From Jul. 2018, To Nov. 2019
Kyoto University, Graduate School of Engineering, Program-Specific Assistant Professor

From Jun. 2016, To Jun. 2018
University of California Berkeley, Department of Chemistry, JSPS Post-Doctoral Fellow

From Apr. 2016, To May 2016
Kyoto University, Graduate School of Pharmaceutical Sciences, Post-Doctoral Fellow

ID,URL

ORCID ID
0000-0003-0952-7098
J-Global ID
202001010134943329
Researcher number
60870863

researchmap URL

https://researchmap.jp/makkuro96suke

Last Updated :2025/06/02

Research

Research Interests

人工酵素のボトムアップ合成

Papers

Exploiting Random Polymers as Functional-Group-Selective Catalysts with Structural Adaptability
Yusei Fujii; Kiyosei Takasu; Yusuke Kuroda
26 May 2025

Net δ-C−H Alkylation of Allyl Alcohols by Ni-Catalyzed Allylic Substitution of Azo-Ene Adducts
Moe Kawajiri; Yusuke Kuroda; Kiyosei Takasu
23 May 2025

Pd-Catalyzed Allylic Substitution of Azo-Ene Adducts Enables Net Allylic C–H Alkylation of Allylic Alcohols
Yusuke Kuroda; Takumi Chiba; Moe Kawajiri; Kiyosei Takasu
Organic Letters, 14 Feb. 2025

Stable and Minimum Size Solubilization of Membrane Proteins with Cocktails of Phospholipid Analogues
Mai Takagi; Ayana Nagatani; Kenichi Kawano; Ayami Hata; Azusa Yokoyama; Koichi Hayashida; Haruka Hoshi; Mao Sakurai; Tsuyoshi Oyama; Yusuke Kuroda; Yousuke Yamaoka; Takahiro Fujiwara; Yohei Miyanoiri; Masaru Hoshino; Yoshiaki Yano; Kiyosei Takasu; Katsumi Matsuzaki
ACS Applied Materials & Interfaces, 20 Nov. 2024

Photo-Induced Pyridylic C(sp³)–H Alkylation with Unactivated Alkenes Enabled by Hydrogen Atom Transfer/Lewis Acid Cocatalysis
Yusuke Kuroda; Hikaru Saito; Tsukasa Tawatari; Kiyosei Takasu
ACS Catalysis, 27 Sep. 2024, Peer-reviewed, Lead author, Corresponding author

Chromic properties of dibenzo[j,l]fluoranthenes exhibiting different resonance contributions.
Kazuma Kurokawa; Naoki Ogawa; Yusuke Kuroda; Yousuke Yamaoka; Hiroshi Takikawa; Kazunori Tsubaki; Kiyosei Takasu
Organic & Biomolecular Chemistry, 30 May 2024, Peer-reviewed

Synthesis of mesoionic triazolones via a formal [3+2] cycloaddition between 4-phenyl-1,2,4-triazoline-3,5-dione and alkynes
Yusuke Kuroda; Maya Krell; Kazuma Kurokawa; Kiyosei Takasu
Chemical Communications, 2024, Peer-reviewed, Lead author, Corresponding author
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An Iridium/Aluminum Cooperative Strategy for the β‐C(sp³)‐H Borylation of Saturated Cyclic Amines
Yusuke Kuroda; Kyungho Park; Yuto Shimazaki; Rong‐Lin Zhong; Shigeyoshi Sakaki; Yoshiaki Nakao
Angewandte Chemie International Edition, 26 Apr. 2023, Peer-reviewed, Lead author

1,1-Carboamination of Terminal Alkenes via a Reaction of Azo-Ene Adducts with Grignard Reagents
Yusuke Kuroda
Organic Letters, 26 Aug. 2022, Peer-reviewed, Lead author, Corresponding author

Remarkable Solvent Effect of Fluorinated Alcohols on Azo–Ene Reactions
Yusuke Kuroda
Chemical and Pharmaceutical Bulletin, May 2022, Peer-reviewed, Lead author, Corresponding author

Palladium-Catalyzed [1,3]-O-to-N Rearrangement of Allylic Imidates
Yusuke Kuroda
Synlett, Jan. 2022, Peer-reviewed, Lead author, Corresponding author

C–C Bond Cleavage Approach to Complex Terpenoids: Development of a Unified Total Synthesis of the Phomactins
Paul R. Leger; Yusuke Kuroda; Stanley Chang; Justin Jurczyk; Richmond Sarpong
Journal of the American Chemical Society, 16 Aug. 2020, Peer-reviewed

C–C Cleavage Approach to C–H Functionalization of Saturated Aza-Cycles
Jose B. Roque; Yusuke Kuroda; Justin Jurczyk; Li-Ping Xu; Jin Su Ham; Lucas T. Göttemann; Charis Amber; Donovon Adpressa; Josep Saurí; Leo A. Joyce; Djamaladdin G. Musaev; Charles S. Yeung; Richmond Sarpong
ACS Catalysis, 16 Jan. 2020, Peer-reviewed

Catalyst-enabled Site-selectivity in the Iridium-catalyzed C–H Borylation of Arenes
Yusuke Kuroda; Yoshiaki Nakao
Chemistry Letters, 05 Sep. 2019, Peer-reviewed, Lead author

Asymmetric Formal Synthesis of (+)-Catharanthine via Desymmetrization of Isoquinuclidine
Masato Kono; Shingo Harada; Tomoyuki Nozaki; Yoshinori Hashimoto; Shun-ichi Murata; Harald Gröger; Yusuke Kuroda; Ken-ichi Yamada; Kiyosei Takasu; Yasumasa Hamada; Tetsuhiro Nemoto
Organic Letters, 17 May 2019, Peer-reviewed

Optical resolution via catalytic generation of chiral auxiliary
Hiroki Kiyama; Tsubasa Inokuma; Yusuke Kuroda; Yousuke Yamaoka; Kiyosei Takasu; Ken-ichi Yamada
Tetrahedron Letters, Jan. 2019, Peer-reviewed

Deconstructive diversification of cyclic amines
Jose B. Roque; Yusuke Kuroda; Lucas T. Göttemann; Richmond Sarpong
Nature, 31 Oct. 2018, Peer-reviewed, Lead author

Isolation, synthesis and bioactivity studies of phomactin terpenoids
Yusuke Kuroda; Karen J. Nicacio; Ildefonso Alves da Silva-Jr; Paul R. Leger; Stanley Chang; Juliana R. Gubiani; Victor M. Deflon; Nozomu Nagashima; Alexander Rode; Katherine Blackford; Antonio G. Ferreira; Lara D. Sette; David E. Williams; Raymond J. Andersen; Sonia Jancar; Roberto G. S. Berlinck; Richmond Sarpong
Nature Chemistry, 30 Sep. 2018, Peer-reviewed, Lead author

Deconstructive fluorination of cyclic amines by carbon-carbon cleavage
Jose B. Roque; Yusuke Kuroda; Lucas T. Göttemann; Richmond Sarpong
Science, 13 Jul. 2018, Peer-reviewed, Lead author

Asymmetric substitution reactions catalyzed by a chiral phosphoric acid
Yusuke Kuroda; Shingo Harada; Ken-Ichi Yamada; Kiyosei Takasu
Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry, 2018, Peer-reviewed, Lead author

Desymmetrization of acid anhydride with asymmetric esterification catalyzed by chiral phosphoric acid
Ken-ichi Yamada; Akinori Oonishi; Yusuke Kuroda; Shingo Harada; Hiroki Kiyama; Yousuke Yamaoka; Kiyosei Takasu
Tetrahedron Letters, 2016, Peer-reviewed

Use of a Catalytic Chiral Leaving Group for Asymmetric Substitutions at sp3-Hybridized Carbon Atoms: Kinetic Resolution of β-Amino Alcohols by p-Methoxybenzylation
Yusuke Kuroda; Shingo Harada; Akinori Oonishi; Hiroki Kiyama; Yousuke Yamaoka; Ken-Ichi Yamada; Kiyosei Takasu
Angewandte Chemie - International Edition, 2016, Peer-reviewed, Lead author

Organocatalytic Enantioselective Intramolecular SN2′ Reaction
Synfacts, 20 Jul. 2015

Organocatalytic Activation of the Leaving Group in the Intramolecular Asymmetric SN2′ Reaction
Yusuke Kuroda; Shingo Harada; Akinori Oonishi; Yousuke Yamaoka; Ken-Ichi Yamada; Kiyosei Takasu
Angewandte Chemie - International Edition, 01 Jul. 2015, Peer-reviewed, Lead author
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Synthesis of 2,3,4,5-tetra-substituted pyrroles via a base-promoted double Michael reaction of oxime-enoates with nitroolefins
Yusuke Kuroda; Kazuto Imaizumi; Ken-Ichi Yamada; Yosuke Yamaoka; Kiyosei Takasu
Tetrahedron Letters, 31 Jul. 2013, Peer-reviewed, Lead author

Selective synthesis of polysubstituted dihydroquinolines and α,β-unsaturated amidines by a catalytic reaction of ynamides with ketimines
Yuusuke Kuroda; Naoya Shindoh; Yoshiji Takemoto; Kiyosei Takasu
Synthesis (Germany), 2013, Peer-reviewed, Lead author

Misc.

Synthesis of biaryl compounds via enolate-olefin metathesis rection
高須清誠; 長尾高明; 高山亜紀; 黒田悠介; 瀧川紘
日本薬学会年会要旨集(Web), 2024

Photo-induced Oxidative Biaryl Coupling
黒川宗希; 高山亜紀; 黒田悠介; 瀧川紘; 高須清誠
日本薬学会年会要旨集(Web), 2024

Synthesis of π-extended aromatic heterocycles driven by ring strain elimination
高須清誠; 長尾高明; 小川直希; 黒川宗希; 高山亜紀; 黒田悠介; 瀧川紘
複素環化学討論会講演要旨集, 2024

Synthesis of π-extended benzofurans via acid induced retro [2+2] cycloaddition
高須清誠; 長尾高明; 黒川宗希; 小川直希; 黒田悠介; 山岡庸介; 瀧川紘
日本薬学会年会要旨集(Web), 2023

Synthesis and studies of isolable medium-sized (1Z,3E)-cycloalkadiene platinum complexes
紀之内颯; 伊藤智裕; 黒田悠介; 山岡庸介; 瀧川紘; 高須清誠
日本薬学会年会要旨集(Web), 2023

Presentations

アゾ化合物を用いる有機合成および人工樹脂触媒による精密分子変換
黒田悠介
公益財団法人乙卯研究所 OB交流会, 16 Mar. 2024, Invited

脂環式アミンの修飾と破壊
黒田悠介
第3回独創的な研究を目指す若手研究者セミナー, 10 Dec. 2021, Invited

External funds: Kakenhi

Deliberate functionalization of allylic C-H bonds via an azo-ene reaction
Grant-in-Aid for Early-Career Scientists
Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Kyoto University
Yusuke KURODA
From 01 Apr. 2021, To 31 Mar. 2023, Project Closed
エン反応;アルケン;アリル位置換反応;アゾ化合物;C－H官能基化;遷移金属;不斉反応
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K15237/

アゾ-エン反応を利用したアリル位炭素－水素結合の立体選択的官能基化
Grant-in-Aid for Early-Career Scientists
Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Kyoto University
黒田悠介
From 01 Apr. 2023, To 31 Mar. 2026, Granted
アゾ化合物;アルキン;ニッケル;アリル位置換反応;アルケン;エン反応;遷移金属;不斉反応
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K14322/

分子ひずみを活用する生体機能分子の創出
Grant-in-Aid for Scientific Research (B)
Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Kyoto University
高須清誠
From 01 Apr. 2023, To 31 Mar. 2026, Granted
分子ひずみ;生物活性分子;有機合成;多環芳香族炭化水素;分子不斉
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23H02604/

分子ひずみを活用する生体機能分子の創出
Grant-in-Aid for Scientific Research (B)
Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Kyoto University
高須清誠
From 01 Apr. 2023, To 31 Mar. 2026, Granted
分子ひずみ;生物活性分子;フロー合成;多環芳香族炭化水素;有機合成;分子不斉
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K27295/

Last Updated :2025/06/02

Education

Teaching subject(s)

From 01 Apr. 2025, To 31 Mar. 2026
Research in Basic Medicinal and Organic Chemistry
3201, Year-long, Graduate School of Pharmaceutical Sciences, 4

From 01 Apr. 2025, To 31 Mar. 2026
Pharmaceutical Laboratory II : Organic Chemistry
C902, Spring, Faculty of Pharmaceutical Sciences, 3

From 01 Apr. 2024, To 31 Mar. 2025
Laboratory Practice in Basic Medicinal and Organic Chemistry
4201, Year-long, Graduate School of Pharmaceutical Sciences, 1

From 01 Apr. 2024, To 31 Mar. 2025
Seminar in Basic Medicinal and Organic Chemistry
2301, Year-long, Graduate School of Pharmaceutical Sciences, 2

From 01 Apr. 2024, To 31 Mar. 2025
Organic Chemistry Seminar
C018, Spring, Faculty of Pharmaceutical Sciences, 2

From 01 Apr. 2024, To 31 Mar. 2025
Organic Chemistry Exercise 2
A018, Spring, Faculty of Pharmaceutical Sciences, 2

From 01 Apr. 2024, To 31 Mar. 2025
Pharmaceutical Laboratory II : Organic Chemistry
C902, Spring, Faculty of Pharmaceutical Sciences, 3

From 01 Apr. 2024, To 31 Mar. 2025
Research in Basic Medicinal and Organic Chemistry
3201, Year-long, Graduate School of Pharmaceutical Sciences, 4

From 01 Apr. 2023, To 31 Mar. 2024
Pharmaceutical Laboratory II : Organic Chemistry
C902, Spring, Faculty of Pharmaceutical Sciences, 3

From 01 Apr. 2023, To 31 Mar. 2024
Pharmaceutical Laboratory 2 : Organic Chemistry
A902, Spring, Faculty of Pharmaceutical Sciences, 4

From 01 Apr. 2023, To 31 Mar. 2024
Organic Chemistry Exercise 2
A018, Spring, Faculty of Pharmaceutical Sciences, 2

From 01 Apr. 2023, To 31 Mar. 2024
Organic Chemistry Seminar
C018, Spring, Faculty of Pharmaceutical Sciences, 2

From 01 Apr. 2022, To 31 Mar. 2023
Pharmaceutical Laboratory II : Organic Chemistry
C902, Spring, Faculty of Pharmaceutical Sciences, 3

From 01 Apr. 2022, To 31 Mar. 2023
Pharmaceutical Laboratory 2 : Organic Chemistry
A902, Spring, Faculty of Pharmaceutical Sciences, 4

Last Updated :2025/06/02

Administration

Faculty management (title, position)

From 01 Apr. 2024, To 31 Mar. 2025
環境・安全衛生委員会　委員

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