Basic Information

Email Address

• Email Address

  katayama.yuta.6jkyoto-u.ac.jp

Professional Memberships

• The Molecular Biology Society of Japan

Academic Degree

• 24 Mar. 2009

  九州大学修士（医科学）
• 20 Mar. 2018

  九州大学博士（医学）

Academic Resume (Graduate Schools)

• 九州大学, 大学院医学研究科医学専攻博士課程, 単位修得退学
• 九州大学, 大学院医学研究科医科学専攻修士課程, 修了

Academic Resume (Undergraduate School/Majors)

• 九州大学, 農学部生物資源学科, 卒業

ID,URL

• ORCID ID

  0000-0003-3124-078X

• J-Global ID

  201801006338712711

researchmap URL

• https://researchmap.jp/ykatayama

Research

Research Interests

• 転写制御
• エピジェネティクス
• 自閉症
• クロマチン
• 分子生物学

Research Areas

• Life sciences, Molecular biology

Papers

• The complex etiology of autism spectrum disorder due to missense mutations of CHD8.

  Taichi Shiraishi; Yuta Katayama; Masaaki Nishiyama; Hirotaka Shoji; Tsuyoshi Miyakawa; Taisuke Mizoo; Akinobu Matsumoto; Atsushi Hijikata; Tsuyoshi Shirai; Kouta Mayanagi; Keiichi I Nakayama

  Molecular psychiatry, 05 Mar. 2024

  
• Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

  Hideo Hagihara; Hirotaka Shoji; Satoko Hattori; Giovanni Sala; Yoshihiro Takamiya; Mika Tanaka; Masafumi Ihara; Mihiro Shibutani; Izuho Hatada; Kei Hori; Mikio Hoshino; Akito Nakao; Yasuo Mori; Shigeo Okabe; Masayuki Matsushita; Anja Urbach; Yuta Katayama; Akinobu Matsumoto; Keiichi I. Nakayama; Shota Katori; Takuya Sato; Takuji Iwasato; Haruko Nakamura; Yoshio Goshima; Matthieu Raveau; Tetsuya Tatsukawa; Kazuhiro Yamakawa; Noriko Takahashi; Haruo Kasai; Johji Inazawa; Ikuo Nobuhisa; Tetsushi Kagawa; Tetsuya Taga; Mohamed Darwish; Hirofumi Nishizono; Keizo Takao; Kiran Sapkota; Kazutoshi Nakazawa; Tsuyoshi Takagi; Haruki Fujisawa; Yoshihisa Sugimura; Kyosuke Yamanishi; Lakshmi Rajagopal; Nanette Deneen Hannah; Herbert Y. Meltzer; Tohru Yamamoto; Shuji Wakatsuki; Toshiyuki Araki; Katsuhiko Tabuchi; Tadahiro Numakawa; Hiroshi Kunugi; Freesia L. Huang; Atsuko Hayata-Takano; Hitoshi Hashimoto; Kota Tamada; Toru Takumi; Takaoki Kasahara; Tadafumi Kato; Isabella A. Graef; Gerald R. Crabtree; Nozomi Asaoka; Hikari Hatakama; Shuji Kaneko; Takao Kohno; Mitsuharu Hattori; Yoshio Hoshiba; Ryuhei Miyake; Kisho Obi-Nagata; Akiko Hayashi-Takagi; Léa J. Becker; Ipek Yalcin; Yoko Hagino; Hiroko Kotajima-Murakami; Yuki Moriya; Kazutaka Ikeda; Hyopil Kim; Bong-Kiun Kaang; Hikari Otabi; Yuta Yoshida; Atsushi Toyoda; Noboru H. Komiyama; Seth G. N. Grant; Michiru Ida-Eto; Masaaki Narita; Ken-ichi Matsumoto; Emiko Okuda-Ashitaka; Iori Ohmori; Tadayuki Shimada; Kanato Yamagata; Hiroshi Ageta; Kunihiro Tsuchida; Kaoru Inokuchi; Takayuki Sassa; Akio Kihara; Motoaki Fukasawa; Nobuteru Usuda; Tayo Katano; Teruyuki Tanaka; Yoshihiro Yoshihara; Michihiro Igarashi; Takashi Hayashi; Kaori Ishikawa; Satoshi Yamamoto; Naoya Nishimura; Kazuto Nakada; Shinji Hirotsune; Kiyoshi Egawa; Kazuma Higashisaka; Yasuo Tsutsumi; Shoko Nishihara; Noriyuki Sugo; Takeshi Yagi; Naoto Ueno; Tomomi Yamamoto; Yoshihiro Kubo; Rie Ohashi; Nobuyuki Shiina; Kimiko Shimizu; Sayaka Higo-Yamamoto; Katsutaka Oishi; Hisashi Mori; Tamio Furuse; Masaru Tamura; Hisashi Shirakawa; Daiki X. Sato; Yukiko U. Inoue; Takayoshi Inoue; Yuriko Komine; Tetsuo Yamamori; Kenji Sakimura; Tsuyoshi Miyakawa

  eLife, 28 Dec. 2023, Peer-reviewed

  
• Effect of brain acidification on depression-related behaviors in diabetes mellitus

  Yusuke Temma; Kisho Obi-Nagata; Yoshio Hoshiba; Ryuhei Miyake; Yuta Katayama; Hideo Hagihara; Norimitsu Suzuki; Tsuyoshi Miyakawa; Keiichi I. Nakayama; Akiko Hayashi-Takagi

  Frontiers in Psychiatry, 29 Nov. 2023

  
• FKBP52 and FKBP51 differentially regulate the stability of estrogen receptor in breast cancer

  Makoto Habara; Yuki Sato; Takahiro Goshima; Masashi Sakurai; Hiroyuki Imai; Hideyuki Shimizu; Yuta Katayama; Shunsuke Hanaki; Takahiro Masaki; Masahiro Morimoto; Sayaka Nishikawa; Tatsuya Toyama; Midori Shimada

  Proceedings of the National Academy of Sciences, 12 Apr. 2022, Peer-reviewed

  
• Identification and characterization of novel proteins associated with CHD4

  Chihiro Sakaguchi; Kazuya Ichihara; Akihiro Nita; Yuta Katayama; Keiichi I. Nakayama

  GENES TO CELLS, Jan. 2022, Peer-reviewed

  
• The autism-associated protein CHD8 is required for cerebellar development and motor function.

  Atsuki Kawamura; Yuta Katayama; Wataru Kakegawa; Daisuke Ino; Masaaki Nishiyama; Michisuke Yuzaki; Keiichi I Nakayama

  Cell reports, 06 Apr. 2021

  
• The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells.

  Akihiro Nita; Yoshiharu Muto; Yuta Katayama; Akinobu Matsumoto; Masaaki Nishiyama; Keiichi I Nakayama

  Cell reports, 02 Feb. 2021

  
• Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain

  Atsuki Kawamura; Yoshifumi Abe; Fumiko Seki; Yuta Katayama; Masaaki Nishiyama; Norio Takata; Kenji F. Tanaka; Hideyuki Okano; Keiichi I. Nakayama

  Molecular Brain, Dec. 2020

  
• Oligodendrocyte dysfunction due to Chd8 mutation gives rise to behavioral deficits in mice.

  Atsuki Kawamura; Yuta Katayama; Masaaki Nishiyama; Hirotaka Shoji; Kota Tokuoka; Yoshifumi Ueta; Mariko Miyata; Tadashi Isa; Tsuyoshi Miyakawa; Akiko Hayashi-Takagi; Keiichi I Nakayama

  Human molecular genetics, 28 May 2020, Peer-reviewed

  
• Characterizing vulnerable brain areas and circuits in mouse models of autism: Towards understanding pathogenesis and new therapeutic approaches.

  Kelvin Hui; Yuta Katayama; Keiichi I Nakayama; Jun Nomura; Takeshi Sakurai

  Neuroscience and biobehavioral reviews, Mar. 2020, Peer-reviewed

  
• Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis.

  Yoshiharu Muto; Toshiro Moroishi; Kazuya Ichihara; Masaaki Nishiyama; Hideyuki Shimizu; Hidetoshi Eguchi; Kyoji Moriya; Kazuhiko Koike; Koshi Mimori; Masaki Mori; Yuta Katayama; Keiichi I Nakayama

  The Journal of experimental medicine, 01 Apr. 2019, Peer-reviewed

  
• The Autism-Related Protein CHD8 Cooperates with C/EBPβ to Regulate Adipogenesis.

  Yasuyuki Kita; Yuta Katayama; Taichi Shiraishi; Takeru Oka; Tetsuya Sato; Mikita Suyama; Yasuyuki Ohkawa; Keishi Miyata; Yuichi Oike; Michiko Shirane; Masaaki Nishiyama; Keiichi I Nakayama

  Cell reports, 15 May 2018, Peer-reviewed

  
• Decreased Brain pH as a Shared Endophenotype of Psychiatric Disorders.

  Hideo Hagihara; Vibeke S Catts; Yuta Katayama; Hirotaka Shoji; Tsuyoshi Takagi; Freesia L Huang; Akito Nakao; Yasuo Mori; Kuo-Ping Huang; Shunsuke Ishii; Isabella A Graef; Keiichi I Nakayama; Cynthia Shannon Weickert; Tsuyoshi Miyakawa

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Feb. 2018, Peer-reviewed

  Access this paper :

  
• 病態モデル動物からアプローチする発達障害の分子病態理解 クロマチンリモデリングの異常によって発症するASDの分子病態

  片山 雄太; 西山 正章; 昌子 浩孝; 大川 恭行; 川村 淳生; 佐藤 哲也; 須山 幹太; 内匠 透; 宮川 剛; 中山 敬一

  生命科学系学会合同年次大会, Dec. 2017

  
• CHD8 haploinsufficiency results in autistic-like phenotypes in mice

  Yuta Katayama; Masaaki Nishiyama; Hirotaka Shoji; Yasuyuki Ohkawa; Atsuki Kawamura; Tetsuya Sato; Mikita Suyama; Toru Takumi; Tsuyoshi Miyakawa; Keiichi I. Nakayama

  NATURE, Sep. 2016, Peer-reviewed

  
• TRIM8 modulates STAT3 activity through negative regulation of PIAS3

  Fumihiko Okumura; Yui Matsunaga; Yuta Katayama; Keiichi I. Nakayama; Shigetsugu Hatakeyama

  JOURNAL OF CELL SCIENCE, Jul. 2010, Peer-reviewed

  

Books and Other Publications

• 日本薬理学雑誌 特集「精神・神経疾患の機能解析イノベーション~分子レベルから in vivo 可視化まで~」 モデルマウスを用いた自閉スペクトラム症の分子メカニズムの解明と治療法の探索

  片山 雄太, Joint work

  中西印刷株式会社, May 2022

  
• 月刊「細胞」2021年6月号特集「ゲノム編集による新しいモデル動物」：自閉症の発症メカニズムの解明と治療法の探索

  片山 雄太; 中山 敬一, Joint work

  ニューサイエンス社, Jun. 2021

  

Awards

• 04 Feb. 2020

  井上研究奨励賞（井上科学振興財団）
• 20 Mar. 2018

  九州大学医学博士優秀賞

External funds: Kakenhi

• Elucidation of the pathogenesis of autism through transcription elongation impairment

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields

  Regional Fish Institute, Ltd (R&D Division);Kyushu University

  Yuta Katayama

  From 30 Jun. 2022, To 31 Mar. 2024, Project Closed

  自閉症;ASD;CHD8;転写;転写伸長;マウスモデル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K19295/
• Elucidation of the developmental mechanism of autism and research for treatment

  Grant-in-Aid for Scientific Research (B)

  Basic Section 51030:Pathophysiologic neuroscience-related

  Kyushu University

  Yuta Katayama

  From 01 Apr. 2020, To 31 Mar. 2023, Project Closed

  自閉症;ASD;CHD8;モデル動物;Chd8

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H03563/
• トランスオミクスによる精神病態分子基盤の特徴量抽出

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyushu University

  片山 雄太

  From 01 Apr. 2019, To 31 Mar. 2021, Project Closed

  自閉症;CHD8;モデル動物;ASD;トランスオミクス;動物モデル

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-19H05220/
• Deciphering pathogenesis of autism spectrum disorder with mouse model

  Grant-in-Aid for Early-Career Scientists

  Basic Section 46010:Neuroscience-general-related

  Kyushu University

  Yuta Katayama

  From 01 Apr. 2018, To 31 Mar. 2020, Project Closed

  自閉症;Chd8;モデルマウス;CHD8;ASD;モデル動物;動物モデル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K14822/