Basic Information

Academic Degree

• 博士（医学）(鳥取大学)

Profile

• Profile

  2011年6月から京都大学iPS細胞研究所でiPS細胞を用いた神経変性疾患の研究を行わせていただいております。

ID,URL

• J-Global ID

  201101080545144069

researchmap URL

• https://researchmap.jp/imamura

Research

Research Areas

• Life sciences, Neuroscience - general

Papers

• Protocol for a phase 2 study of bosutinib for amyotrophic lateral sclerosis using real-world data: induced pluripotent stem cell-based drug repurposing for amyotrophic lateral sclerosis medicine (iDReAM) study.

  Keiko Imamura; Yuishin Izumi; Naohiro Egawa; Takashi Ayaki; Makiko Nagai; Kazutoshi Nishiyama; Yasuhiro Watanabe; Takenobu Murakami; Ritsuko Hanajima; Hiroshi Kataoka; Takao Kiriyama; Hitoki Nanaura; Kazuma Sugie; Takehisa Hirayama; Osamu Kano; Masahiro Nakamori; Hirofumi Maruyama; Shotaro Haji; Koji Fujita; Naoki Atsuta; Harutsugu Tatebe; Takahiko Tokuda; Naoto Takahashi; Akiko Morinaga; Riko Tabuchi; Motoki Oe; Mihoko Kobayashi; Kasia Lobello; Satoshi Morita; Gen Sobue; Ryosuke Takahashi; Haruhisa Inoue

  BMJ open, 26 Oct. 2024

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• Mutant α-synuclein causes death of human cortical neurons via ERK1/2 and JNK activation.

  Hidefumi Suzuki; Naohiro Egawa; Keiko Imamura; Takayuki Kondo; Takako Enami; Kayoko Tsukita; Mika Suga; Yuichiro Yada; Ran Shibukawa; Ryosuke Takahashi; Haruhisa Inoue

  Molecular brain, 05 Mar. 2024

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• Safety and tolerability of bosutinib in patients with amyotrophic lateral sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase 1 trial

  Keiko Imamura; Yuishin Izumi; Makiko Nagai; Kazutoshi Nishiyama; Yasuhiro Watanabe; Ritsuko Hanajima; Naohiro Egawa; Takashi Ayaki; Ryosuke Oki; Koji Fujita; Ryuji Uozumi; Akiko Morinaga; Tomoko Hirohashi; Yosuke Fujii; Takuya Yamamoto; Harutsugu Tatebe; Takahiko Tokuda; Naoto Takahashi; Satoshi Morita; Ryosuke Takahashi; Haruhisa Inoue

  eClinicalMedicine, Oct. 2022

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• Leber's Hereditary Optic Neuropathy with Olivocerebellar Degeneration due to G11778A and T3394C Mutations in the Mitochondrial DNA

  Kazuhiro Nakaso; Yoshiki Adachi; Emi Fusayasu; Koji Doi; Keiko Imamura; Kenichi Yasui; Kenji Nakashima

  JOURNAL OF CLINICAL NEUROLOGY, Sep. 2012, Peer-reviewed

  
• Enhanced aggregate formation by dopamine, L-dopa, and quinone in PC12 cells

  Kazuhiro Nakaso; Satoru Ito; Yuko Yoshimoto; Keiko Imamura; Takao Takeshima; Kenji Nakashima

  NEUROSCIENCE RESEARCH, 2007, Peer-reviewed

  
• MiR-33a is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.

  Fumiko Nakazeki; Itaru Tsuge; Takahiro Horie; Keiko Imamura; Kayoko Tsukita; Akitsu Hotta; Osamu Baba; Yasuhide Kuwabara; Tomohiro Nishino; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Shuhei Tsuji; Motoko Naitoh; Shigehiko Suzuki; Yuishin Izumi; Toshitaka Kawarai; Ryuji Kaji; Takeshi Kimura; Haruhisa Inoue; Koh Ono

  Clinical science (London, England : 1979), 28 Feb. 2019, Peer-reviewed

  
• Generation of a human induced pluripotent stem cell line, BRCi009-A, derived from a patient with glycogen storage disease type 1a.

  Yukimi Katagami; Takayuki Kondo; Mika Suga; Yuichiro Yada; Keiko Imamura; Ran Shibukawa; Yukako Sagara; Yasue Okanishi; Kayoko Tsukita; Kenji Hirayama; Takumi Era; Haruhisa Inoue

  Stem cell research, Dec. 2020, Peer-reviewed

  
• Generation of a human induced pluripotent stem cell line derived from a Parkinson's disease patient carrying SNCA duplication.

  Hidefumi Suzuki; Naohiro Egawa; Takayuki Kondo; Keiko Imamura; Takako Enami; Kayoko Tsukita; Mika Suga; Ran Shibukawa; Yasue Okanishi; Tsuyoshi Uchiyama; Haruhisa Inoue; Ryosuke Takahashi

  Stem cell research, May 2020, Peer-reviewed

  
• Cytoplasmic aggregates of dynactin in iPSC-derived tyrosine hydroxylase-positive neurons from a patient with Perry syndrome.

  Takayasu Mishima; Taizo Ishikawa; Keiko Imamura; Takayuki Kondo; Yasushi Koshiba; Ryosuke Takahashi; Jun Takahashi; Akihiro Watanabe; Naoki Fujii; Yoshio Tsuboi; Haruhisa Inoue

  Parkinsonism & related disorders, Sep. 2016, Peer-reviewed

  
• Human induced pluripotent stem cells generated from a patient with idiopathic basal ganglia calcification.

  Yuichiro Yada; Takayuki Kondo; Mika Suga; Kayoko Tsukita; Takako Enami; Ran Shibukawa; Yukako Sagara; Yasue Okanishi; Keiko Imamura; Takeshi Kihara; Haruhisa Inoue

  Stem cell research, May 2021

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• Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice.

  Hiroki Takeuchi; Keiko Imamura; Bin Ji; Kayoko Tsukita; Takako Enami; Keizo Takao; Tsuyoshi Miyakawa; Masato Hasegawa; Naruhiko Sahara; Nobuhisa Iwata; Makoto Inoue; Hideo Hara; Takeshi Tabira; Maiko Ono; John Q Trojanowski; Virginia M-Y Lee; Ryosuke Takahashi; Tetsuya Suhara; Makoto Higuchi; Haruhisa Inoue

  NPJ vaccines, 25 Mar. 2020

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• Establishment of DYT5 patient-specific induced pluripotent stem cells with a GCH1 mutation

  Nagahisa Murakami; Taizo Ishikawa; Takayuki Kondo; Keiko Imamura; Kayoko Tsukita; Takako Enami; Misato Funayama; Ran Shibukawa; Shinichi Matsumoto; Yuishin Izumi; Etsuro Ohta; Fumiya Obata; Ryuji Kaji; Haruhisa Inoue

  STEM CELL RESEARCH, Oct. 2017, Peer-reviewed

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• Modeling Alzheimer's Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular A beta and Differential Drug Responsiveness

  Takayuki Kondo; Masashi Asai; Kayoko Tsukita; Yumiko Kutoku; Yutaka Ohsawa; Yoshihide Sunada; Keiko Imamura; Naohiro Egawa; Naoki Yahata; Keisuke Okita; Kazutoshi Takahashi; Isao Asaka; Takashi Aoi; Akira Watanabe; Kaori Watanabe; Chie Kadoya; Rie Nakano; Dai Watanabe; Kei Maruyama; Osamu Hori; Satoshi Hibino; Tominari Choshi; Tatsutoshi Nakahata; Hiroyuki Hioki; Takeshi Kaneko; Motoko Naitoh; Katsuhiro Yoshikawa; Satoko Yamawaki; Shigehiko Suzuki; Ryuji Hata; Shu-ichi Ueno; Tsuneyoshi Seki; Kazuhiro Kobayashi; Tatsushi Toda; Kazuma Murakami; Kazuhiro Irie; William L. Klein; Hiroshi Mori; Takashi Asada; Ryosuke Takahashi; Nobuhisa Iwata; Shinya Yamanaka; Haruhisa Inoue

  CELL STEM CELL, Apr. 2013, Peer-reviewed

  
• One-step induction of photoreceptor-like cells from human iPSCs by delivering transcription factors.

  Yuki Otsuka; Keiko Imamura; Akio Oishi; Takayuki Kondo; Mika Suga; Yuichiro Yada; Ran Shibukawa; Yasue Okanishi; Yukako Sagara; Kayoko Tsukita; Akitaka Tsujikawa; Haruhisa Inoue

  iScience, 15 Apr. 2022

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• Induction of inverted morphology in brain organoids by vertical-mixing bioreactors.

  Dang Ngoc Anh Suong; Keiko Imamura; Ikuyo Inoue; Ryotaro Kabai; Satoko Sakamoto; Tatsuya Okumura; Yoshikazu Kato; Takayuki Kondo; Yuichiro Yada; William L Klein; Akira Watanabe; Haruhisa Inoue

  Communications biology, 22 Oct. 2021

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• Simple derivation of skeletal muscle from human pluripotent stem cells using temperature-sensitive Sendai virus vector.

  Ghee Wan Tan; Takayuki Kondo; Keiko Imamura; Mika Suga; Takako Enami; Ayako Nagahashi; Kayoko Tsukita; Ikuyo Inoue; Jitsutaro Kawaguchi; Tsugumine Shu; Haruhisa Inoue

  Journal of cellular and molecular medicine, Oct. 2021

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• Prediction Model of Amyotrophic Lateral Sclerosis by Deep Learning with Patient Induced Pluripotent Stem Cells.

  Keiko Imamura; Yuichiro Yada; Yuishin Izumi; Mitsuya Morita; Akihiro Kawata; Takayo Arisato; Ayako Nagahashi; Takako Enami; Kayoko Tsukita; Hideshi Kawakami; Masanori Nakagawa; Ryosuke Takahashi; Haruhisa Inoue

  Annals of neurology, Jun. 2021

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• iPSC screening for drug repurposing identifies anti-RNA virus agents modulating host cell susceptibility.

  Keiko Imamura; Yasuteru Sakurai; Takako Enami; Ran Shibukawa; Yohei Nishi; Akira Ohta; Tsugumine Shu; Jitsutaro Kawaguchi; Sayaka Okada; Thomas Hoenen; Jiro Yasuda; Haruhisa Inoue

  FEBS open bio, May 2021

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• Generation of Motor Neurons from Human ESCs/iPSCs Using Sendai Virus Vectors.

  Keiko Imamura; Jitsutaro Kawaguchi; Tsugumine Shu; Haruhisa Inoue

  Methods in molecular biology (Clifton, N.J.), 2021

  
• Prediction of Compound Bioactivities Using Heat-Diffusion Equation.

  Tadashi Hidaka; Keiko Imamura; Takeshi Hioki; Terufumi Takagi; Yoshikazu Giga; Mi-Ho Giga; Yoshiteru Nishimura; Yoshinobu Kawahara; Satoru Hayashi; Takeshi Niki; Makoto Fushimi; Haruhisa Inoue

  Patterns (New York, N.Y.), 11 Dec. 2020

  
• Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice.

  Hiroki Takeuchi; Keiko Imamura; Bin Ji; Kayoko Tsukita; Takako Enami; Keizo Takao; Tsuyoshi Miyakawa; Masato Hasegawa; Naruhiko Sahara; Nobuhisa Iwata; Makoto Inoue; Hideo Hara; Takeshi Tabira; Maiko Ono; John Q Trojanowski; Virginia M-Y Lee; Ryosuke Takahashi; Tetsuya Suhara; Makoto Higuchi; Haruhisa Inoue

  NPJ vaccines, 2020

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• is a therapeutic target in SPG4-related hereditary spastic paraplegia human neurons.

  Fumiko Nakazeki; Itaru Tsuge; Takahiro Horie; Keiko Imamura; Kayoko Tsukita; Akitsu Hotta; Osamu Baba; Yasuhide Kuwabara; Tomohiro Nishino; Tetsushi Nakao; Masataka Nishiga; Hitoo Nishi; Yasuhiro Nakashima; Yuya Ide; Satoshi Koyama; Masahiro Kimura; Shuhei Tsuji; Motoko Naitoh; Shigehiko Suzuki; Yuishin Izumi; Toshitaka Kawarai; Ryuji Kaji; Takeshi Kimura; Haruhisa Inoue; Koh Ono

  Clinical Science, 22 Feb. 2019, Peer-reviewed

  
• A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.

  Naomi Tsuburaya; Kengo Homma; Tsunehiko Higuchi; Andrii Balia; Hiroyuki Yamakoshi; Norio Shibata; Seiichi Nakamura; Hidehiko Nakagawa; Shin-Ichi Ikeda; Naoki Umezawa; Nobuki Kato; Satoshi Yokoshima; Masatoshi Shibuya; Manabu Shimonishi; Hirotatsu Kojima; Takayoshi Okabe; Tetsuo Nagano; Isao Naguro; Keiko Imamura; Haruhisa Inoue; Takao Fujisawa; Hidenori Ichijo

  Nature communications, 10 Jul. 2018

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• Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons

  Kenichi Komatsu; Keiko Imamura; Hirofumi Yamashita; Jean-Pierre Julien; Ryosuke Takahashi; Haruhisa Inoue

  NEUROREPORT, Jan. 2018, Peer-reviewed

  
• iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease.

  Takayuki Kondo; Keiko Imamura; Misato Funayama; Kayoko Tsukita; Michiyo Miyake; Akira Ohta; Knut Woltjen; Masato Nakagawa; Takashi Asada; Tetsuaki Arai; Shinobu Kawakatsu; Yuishin Izumi; Ryuji Kaji; Nobuhisa Iwata; Haruhisa Inoue

  Cell reports, 21 Nov. 2017

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• Antisense Oligonucleotides Reduce RNA Foci in Spinocerebellar Ataxia 36 Patient iPSCs.

  Kosuke Matsuzono; Keiko Imamura; Nagahisa Murakami; Kayoko Tsukita; Takuya Yamamoto; Yuishin Izumi; Ryuji Kaji; Yasuyuki Ohta; Toru Yamashita; Koji Abe; Haruhisa Inoue

  Molecular therapy. Nucleic acids, 15 Sep. 2017

  
• Analysis of neural crest cells from Charcot-Marie-Tooth disease patients demonstrates disease-relevant molecular signature

  Fukiko Kitani-Morii; Keiko Imamura; Takayuki Kondo; Ryo Ohara; Takako Enami; Ran Shibukawa; Takuya Yamamoto; Kazuya Sekiguchi; Junya Toguchida; Toshiki Mizuno; Masanori Nakagawa; Haruhisa Inoue

  NEUROREPORT, Sep. 2017, Peer-reviewed

  
• The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis

  Keiko Imamura; Yuishin Izumi; Akira Watanabe; Kayoko Tsukita; Knut Woltjen; Takuya Yamamoto; Akitsu Hotta; Takayuki Kondo; Shiho Kitaoka; Akira Ohta; Akito Tanaka; Dai Watanabe; Mitsuya Morita; Hiroshi Takuma; Akira Tamaoka; Tilo Kunath; Selina Wray; Hirokazu Furuya; Takumi Era; Kouki Makioka; Koichi Okamoto; Takao Fujisawa; Hideki Nishitoh; Kengo Homma; Hidenori Ichijo; Jean-Pierre Julien; Nanako Obata; Masato Hosokawa; Haruhiko Akiyama; Satoshi Kaneko; Takashi Ayaki; Hidefumi Ito; Ryuji Kaji; Ryosuke Takahashi; Shinya Yamanaka; Haruhisa Inoue

  SCIENCE TRANSLATIONAL MEDICINE, May 2017, Peer-reviewed

  
• Simple Derivation of Spinal Motor Neurons from ESCs/iPSCs Using Sendai Virus Vectors

  Kazuya Goto; Keiko Imamura; Kenichi Komatsu; Kohnosuke Mitani; Kazuhiro Aiba; Norio Nakatsuji; Makoto Inoue; Akihiro Kawata; Hirofumi Yamashita; Ryosuke Takahashi; Haruhisa Inoue

  MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, Mar. 2017, Peer-reviewed

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• Proteasome impairment in neural cells derived from HMSN-P patient iPSCs

  Nagahisa Murakami; Keiko Imamura; Yuishin Izumi; Naohiro Egawa; Kayoko Tsukita; Takako Enami; Takuya Yamamoto; Toshitaka Kawarai; Ryuji Kaji; Haruhisa Inoue

  MOLECULAR BRAIN, Feb. 2017, Peer-reviewed

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• Genetic and pharmacological correction of aberrant dopamine synthesis using patient iPSCs with BH4 metabolism disorders

  Taizo Ishikawa; Keiko Imamura; Takayuki Kondo; Yasushi Koshiba; Satoshi Hara; Hiroshi Ichinose; Mahoko Furujo; Masako Kinoshita; Tomoko Oeda; Jun Takahashi; Ryosuke Takahashi; Haruhisa Inoue

  HUMAN MOLECULAR GENETICS, Dec. 2016, Peer-reviewed

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• Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons

  Keiko Imamura; Naruhiko Sahara; Nicholas M. Kanaan; Kayoko Tsukita; Takayuki Kondo; Yumiko Kutoku; Yutaka Ohsawa; Yoshihide Sunada; Koichi Kawakami; Akitsu Hotta; Satoshi Yawata; Dai Watanabe; Masato Hasegawa; John Q. Trojanowski; Virginia M. -Y. Lee; Tetsuya Suhara; Makoto Higuchi; Haruhisa Inoue

  SCIENTIFIC REPORTS, Oct. 2016, Peer-reviewed

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• Peripheral Nerve Hypertrophy in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Detected by Ultrasonography Reply

  Keiko Imamura; Yuuki Tajiri; Hisanori Kowa; Kenji Nakashima

  INTERNAL MEDICINE, 2009, Peer-reviewed

  
• Prevalence of Dementia in the Rural Island Town of Ama-cho, Japan

  Kenji Wada-Isoe; Yusuke Uemura; Yutaka Suto; Koji Doi; Keiko Imamura; Ai Hayashi; Michio Kitayama; Yasuhiro Watanabe; Yoshiki Adachi; Kenji Nakashima

  NEUROEPIDEMIOLOGY, 2009, Peer-reviewed

  
• Peripheral Nerve Hypertrophy in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Detected by Ultrasonography

  Keiko Imamura; Yuuki Tajiri; Hisanori Kowa; Kenji Nakashima

  INTERNAL MEDICINE, 2009, Peer-reviewed

  
• Prarnipexole has astrocyte-mediated neuroprotective effects against lactacystin toxicity

  Keiko Imamura; Takao Takeshima; Kazuhiro Nakaso; Satoru Ito; Kenji Nakashima

  NEUROSCIENCE LETTERS, Aug. 2008, Peer-reviewed

  
• Executive dysfunction in non-demented Parkinson's disease patients with hallucinations

  K. Imamura; K. Wada-Isoe; M. Kitayama; K. Nakashima

  ACTA NEUROLOGICA SCANDINAVICA, Apr. 2008, Peer-reviewed

  
• Increased plasma matrix metalloproteinase-9 levels in migraineurs

  Keiko Imamura; Takao Takeshima; Emi Fusayasu; Kenji Nakashima

  HEADACHE, Jan. 2008, Peer-reviewed

  
• The effect of donepezil on increased regional cerebral blood flow in the posterior cingulate cortex of a patient with Parkinson's disease dementia

  Keiko Imamura; Kenji Wada-Isoe; Hisanori Kowa; Yoshio Tanabe; Kenji Nakashima

  NEUROCASE, 2008, Peer-reviewed

  
• Homocysteine is toxic for dopaminergic neurons in primary mesencephalic culture

  Keiko Imamura; Takao Takeshima; Kazuhiro Nakaso; Kenji Nakashima

  NEUROREPORT, Aug. 2007, Peer-reviewed

  
• D-beta-hydroxybutyrate protects dopaminergic SH-SY5Y cells in a rotenone model of Parkinson's disease

  Keiko Imamura; Takao Takeshima; Yoshihiro Kashiwaya; Kazuhiro Nakaso; Kenji Nakashima

  JOURNAL OF NEUROSCIENCE RESEARCH, Nov. 2006, Peer-reviewed

  
• Intravascular large B-cell lymphoma following a relapsing stroke with temporary fever: A brain biopsy case

  Keiko Imamura; Etsuko Awaki; Yasuaki Aoyama; Shinji Kondo; Yasushi Horie; Eisaku Ohama; Kenji Nakashima

  INTERNAL MEDICINE, 2006, Peer-reviewed

  
• A case of malignant fibrous histiocytoma with metastatic brain tumors after tumorgenic embolism

  Keiko Imamura; Kenji Wada; Kenichi Yasui; Kazuhiro Nakaso; Yasuhiro Watanabe; Hisanori Kowa; Kenji Nakashima

  Clinical Neurology, Jul. 2004, Peer-reviewed

  

Misc.

• Matrix metalloproteinase-9(MMP-9)と片頭痛

  竹島 多賀夫; 今村 恵子; 房安 恵美; 古和 久典; 中島 健二

  日本頭痛学会誌, Jun. 2010

  
• 腫瘍塞栓後に転移性脳腫瘍を形成した悪性線維性組織球腫の1例

  今村 恵子; 和田 健二; 安井 建一; 中曽 一裕; 渡辺 保裕; 古和 久典; 中島 健二

  臨床神経学, Jul. 2004

  
• Induced pluripotent stem cell-based Drug Repurposing for Amyotrophic lateral sclerosis Medicine (iDReAM) study: protocol for a phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis patients.

  Keiko Imamura; Yuishin Izumi; Haruhiko Banno; Ryuji Uozumi; Satoshi Morita; Naohiro Egawa; Takashi Ayaki; Makiko Nagai; Kazutoshi Nishiyama; Yasuhiro Watanabe; Ritsuko Hanajima; Ryosuke Oki; Koji Fujita; Naoto Takahashi; Takafumi Ikeda; Akira Shimizu; Akiko Morinaga; Tomoko Hirohashi; Yosuke Fujii; Ryosuke Takahashi; Haruhisa Inoue

  BMJ open, 02 Dec. 2019

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Awards

• 03 Mar. 2021

  第１３回京都大学たちばな賞（優秀女性研究者賞）

External funds: Kakenhi

• Research on dementia therapeutics targeting tau splicing

  Grant-in-Aid for Scientific Research (C)

  Basic Section 52030:Psychiatry-related

  Kyoto University

  Imamura Keiko

  From 01 Apr. 2020, To 31 Mar. 2024, Project Closed

  タウ;スプライシング;iPS細胞;脳オルガノイド;アンチセンスオリゴ;前頭側頭葉変性症;tauopathy;splicing;ASO

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K07968/
• In vivo reprogramming for ALS regenerative therapy

  Grant-in-Aid for Scientific Research (B)

  Basic Section 51030:Pathophysiologic neuroscience-related

  Kyoto University

  Inoue Haruhisa

  From 01 Apr. 2018, To 31 Mar. 2021, Project Closed

  ALS;生体内ダイレクトリプログラミング;運動神経細胞;再生医療;ウイルスベクター;ダイレクトリプログラミング;細胞移植;神経再生

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18H02717/
• The propagation of tau oligomers and the neurotoxicity

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Imamura keiko

  From 01 Apr. 2017, To 31 Mar. 2020, Project Closed

  タウ;タウオリゴマー;前頭側頭葉変性症;iPS細胞;神経活動;FTLD;オリゴマー

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K10297/
• The effect of ketone body on the transplantation of dopaminergicstem cells

  Grant-in-Aid for Young Scientists (B)

  Tottori University

  Keiko IMAMURA

  From 01 Apr. 2007, To 31 Mar. 2009, Project Closed

  ケトン体;パーキンソン病;神経幹細胞;幹細胞移植;ドパミン神経細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790606/
• A study for molecular mechanism of familial migraine headache and its model with primary neural and astrocytes culture

  Grant-in-Aid for Scientific Research (C)

  Tottori University

  Takao TAKESHIMA

  From 01 Apr. 2006, To 31 Mar. 2008, Project Closed

  astrocyte;migraine;glia;MMP-9;CSD;comorbidity, astrocyte;migraine;glia;MMP-9;CSD;comorbidity

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18590941/
• ケトン体の神経保護効果とドパミン神経幹細胞における増殖・分化シグナルへの関与

  Grant-in-Aid for Young Scientists (B)

  Tottori University

  今村 恵子

  From 01 Apr. 2005, To 31 Mar. 2007, Project Closed

  神経幹細胞;ドパミン;ケトン体;パーキンソン病;分化シグナル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17790580/
• Regulation of molecular mechanism in growth and differentiation of dopaminergic neural progenitors and application for treatment of Parkinson's disease.

  Grant-in-Aid for Scientific Research (C)

  National University Corporation Tottori University

  Takao TAKESHIMA

  From 01 Apr. 2003, To 31 Mar. 2006, Project Closed

  神経幹細胞;ドパミン神経;D-β hydroxybutyrate;PI3K-Nrf2;THprom-GFP;rotenone;Pl3K-Nrf2;Thprom-GFP;D- β hydroxybutyrate;GAPDH;ブロテアソーム;nurr-1;脳由来神経栄養因子;プロテアソーム, neural progenitors;dopaminergic neuron;D-β hydroxybutyrate;PI3K-Nrf2;THprom-GFP;rotenone

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15590890/
• AIと幹細胞技術を用いた筋萎縮性側索硬化症の層別化研究

  Grant-in-Aid for Scientific Research (C)

  Basic Section 51030:Pathophysiologic neuroscience-related

  Kyoto University

  今村 恵子

  From 01 Apr. 2023, To 31 Mar. 2026, Granted

  筋萎縮性側索硬化症;iPS細胞;AI;層別化;オルガノイド

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K06827/

Administration

Faculty management (title, position)

• 共通機器管理運営委員会3号委員