Basic Information

Faculty

• Faculty of Engineering

Email Address

• Email Address

  matsumoto.satomi.7jkyoto-u.ac.jp

Professional Memberships

• From May 2024, To Present

  科学とナノ・マイクロシステム学会
• From Jul. 2022, To Present

  The Japanese Vascular Biology and Medicine Organization
• From Aug. 2021, To Present

  North American Vascular Biology Organization
• From Jul. 2016, To Aug. 2020

  科学とナノ・マイクロシステム学会
• From Nov. 2015, To Mar. 2019

  The Japan Society for Precision Engineering

Academic Degree

• 31 Mar. 2016

  東京大学修士（工学）
• 31 Mar. 2019

  東京大学博士（工学）

Academic Resume (Graduate Schools)

• 東京大学, 大学院工学系研究科博士課程精密工学専攻, 修了
• 東京大学, 大学院工学系研究科修士課程精密工学専攻, 修了

Academic Resume (Undergraduate School/Majors)

• 東京大学, 工学部精密工学科, 卒業

Research History

• From Dec. 2019, To Present

  Kyoto University, Graduate School of Engineering Department of Micro Engineering, Postdoctoral scholar
• From May 2019, To Dec. 2022

  University of California, Irvine, The Department of Molecular Biology and Biochemistry, Postdoctoral scholar
• From Apr. 2019, To May 2019

  The University of Tokyo, The Graduate School of Engineering Department of Precision Engineering, Postdoctoral scholar

ID,URL

• J-Global ID

  202301004840269918

researchmap URL

• https://researchmap.jp/satomim

Research

Research Interests

• Liver zonation
• Organ-on-a-chip
• angiogenesis
• Liver metabolism
• Microphysiological model
• Microfluidics

Research Areas

• Life sciences, Biomedical engineering
• Nanotechnology/Materials, Nanobioscience
• Nanotechnology/Materials, Nano/micro-systems

Papers

• Investigation of the hepatic respiration and liver zonation on rat hepatocytes using an integrated oxygen biosensor in a microscale device

  Satomi Matsumoto; Astia R. Safitri; Mathieu Danoy; Toshiro Maekawa; Haruyuki Kinoshita; Marie Shinohara; Yasuyuki Sakai; Teruo Fujii; Eric Leclerc

  Biotechnology Progress, 12 Jun. 2019, Peer-reviewed, Lead author

  
• Sensing of oxygen concentration in a microfluidic device mimicking liver 3D microarchitecture

  Manon Boul; Satomi Matsumoto; Marie Shinohara; Yasuyuki Sakai; Teruo Fujii; Anne Dubart-Kupperschmitt; Eric Leclerc; Bruno Le Pioufle

  23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, 2019

  
• Investigation of drug metabolism with liver zonation model using oxygen gradient in a microfluidic device

  Satomi Matsumoto; Eric Leclec; Astia Rizki-Safitri; Mathieu Danoy; Toshiro Maekawa; Haruyuki Kinoshita; Marie Shinohara; Kikuo Komori; Yasuyuki Sakai; Teruo Fujii

  23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019, 2019

  
• Integration of an oxygen sensor into a polydymethylsiloxane hepatic culture device for two-dimensional gradient characterization

  Satomi Matsumoto; Eric Leclerc; Toshiro Maekawa; Haruyuki Kinoshita; Marie Shinohara; Kikuo Komori; Yasuyuki Sakai; Teruo Fujii

  Sensors and Actuators B: Chemical, Nov. 2018, Peer-reviewed, Lead author

  
• Recapitulation of rat hepatocellular function forming oxygen gradient in a microfluidic cell culture device

  Satomi Matsumoto; Eric Leclerc; Astia Rizki Safitri; Mathieu Danoy; Toshiro Maekawa; Haruyuki Kinoshita; Marie Shinohara; Kikuo Komori; Yasuyuki Sakai; Teruo Fujii

  22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018, 2018

  

Misc.

• Visualization of oxygen gradient in a PDMS hepatocyte culture device

  S. Matsumoto; E. Leclerc; T. Maekawa; H. Kinoshita; M. Shinohara; K. Komori; Y. Sakai; T. Fujii

  20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Jan. 2016

  
• In vitroにおける肝機能変化の酸素濃度依存性に関する検証

  松本倫実; Eric Leclerc; 前川敏郎; 木下晴之; 篠原満利恵; 小森喜久夫; 酒井 康行; 藤井 輝夫

  化学とマイクロ・ナノシステム学会第37回研究会予稿集, May 2018, Lead author

  
• 肝細胞培養デバイス内部における細胞機能の評価

  松本倫実; Eric Leclerc; 前川敏郎; 木下晴之; 篠原満利恵; 小森喜久夫; 酒井 康行; 藤井 輝夫

  化学とマイクロ・ナノシステム学会第36回研究会予稿集, Oct. 2017, Lead author

  
• 肝細胞培養デバイスにおける層流を用いた局所的細胞回収機構に関する基礎的検証

  松本倫実; Eric Leclerc; 前川敏郎; 木下晴之; 篠原満利恵; 小森喜久夫; 酒井 康行; 藤井 輝夫

  化学とマイクロ・ナノシステム学会第35回研究会予稿集, May 2017, Lead author

  
• 肝細胞培養デバイスにおけるトリプシンを用いた局所的細胞回収方法の検討

  松本 倫実; Leclerc Eric; 前川 敏郎; 木下 晴之; 篠原 満利恵; 小森 喜久夫; 酒井 康行; 藤井 輝夫

  精密工学会学術講演会講演論文集, 2017

  
• ガス透過性を低下させたマイクロ流体デバイス内での肝細胞培養条件の決定

  松本倫実; Eric Leclerc; 前川敏郎; 木下晴之; 篠原満利恵; 小森喜久夫; 酒井 康行; 藤井 輝夫

  化学とマイクロ・ナノシステム学会第34回研究会予稿集, Sep. 2016, Lead author

  
• 肝細胞培養マイクロ流体デバイス内に形成された酸素濃度分布の可視化

  松本倫実; Eric Leclerc; 前川敏郎; 木下晴之; 篠原満利恵; 小森喜久夫; 酒井 康行; 藤井 輝夫

  化学とマイクロ・ナノシステム学会第33回研究会予稿集, Apr. 2016, Lead author

  
• Verification of Visualization of Oxygen Concentration in a Microfluidic Hepatocytes Culture Device

  Matsumoto Satomi; Leclerc Eric; Maekawa Toshiro; Kinoshita Haruyuki; Shinohara Marie; Komori Kikuo; Sakai Yasuyuki; Fujii Teruo

  Proceedings of JSPE Semestrial Meeting, 2016

  
• 聴覚刺激及びリズムの周期性が運動主体感に与える影響の評価

  松本倫実

  ライフサポート学会誌, Mar. 2014, Lead author

  

Presentations

• Recapitulating the Arteriovenous Malformations of Hereditary Hemorrhagic Telangiectasia in a Microfluidic Model

  S. Matsumoto; J. S. Fang; Y. Chen; A. P. Lee; C. C. W. Hughes

  22nd International Vascular Biology Meeting (IVBM 2022), Oct. 2022

  
• In Vivo Vascular Formation in a Microfluidic Device with Liver Sinusoidal Endothelial Cells

  S. Matsumoto; J. S. Fang; Y. Chen; A. P. Lee; C. C. W. Hughes

  The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2022), Oct. 2022

  
• マイクロ流体技術およびMEMSを応用した生体模倣システム（MPS）の開発

  松本倫実

  第4回精密工学セミナー, Sep. 2022, Invited

  
• Recapitulating the Arteriovenous Malformations of Hereditary Hemorrhagic Telangiectasia in a Microfluidic Model

  S. Matsumoto; J. S. Fang; Y. Chen; A. P. Lee; C. C. W. Hughes

  The 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2021), Oct. 2021

  
• A Vascularized Micro Liver Model Accurately Models Human Liver Albumin Production and Metabolic Response to Phenacetin

  S. Matsumoto; J. S. Fang; Y. Chen; A. P. Lee; C. C. W. Hughes

  Vascular Biology 2021, Oct. 2021

  
• A Vascularized Micro Liver Model Supports Robust Albumin and CYP450 Expression by Human Hepatocytes

  S. Matsumoto; J. S. Fang; Y. Chen; D. Zhao; A. P. Lee; C. C. W. Hughes

  The 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020), Oct. 2020

  
• Sensing of Oxygen Concentration in a Microfluidic Device Mimicking Liver 3D Microarchitecture

  M. Boul; S. Matsumoto; Y. Sakai; T. Fujii; A. D. Kupperschmi; E. Leclerc; B. Le Pioufle

  The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019), Oct. 2019

  
• Investigation of Drug Metabolism with Liver Zonation Model Using Oxygen Gradient in a Microfluidic Device

  S. Matsumoto; E. Leclerc; A. Rizki-Safitri; M. Danoy; T. Maekawa; H. Kinoshita; M. Shinohara; K. Komori; Y. Sakai; T. Fujii

  The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2019), Oct. 2019

  
• Recapitulation of Rat Hepatocellular Function Forming Oxygen Gradient in a Microfluidic Cell Culture Device

  S. Matsumoto; E. Leclerc; A. Rizki-Safitri; M. Danoy; T. Maekawa; H. Kinoshita; M. Shinohara; K. Komori; Y. Sakai; T. Fujii

  The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Oct. 2018

  
• Visualization of the Difference of Rat Hepatocellular Function under Oxygen Gradient

  S. Matsumoto; E. Leclerc; T. Maekawa; H. Kinoshita; M. Shinohara; K. Komori; Y. Sakai; T. Fujii

  10th International Symposium on Microchemistry and Microsystems (ISMM 2018), Jun. 2018

  
• Position-selective Cell Sampling Microfluidic System Using Localized Laminar Flows

  S. Matsumoto; E. Leclerc; T. Maekawa; H. Kinoshita; M. Shinohara; K. Komori; Y. Sakai; T. Fujii

  The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Oct. 2017

  
• Position-selective Cell Sampling Using Localized Trypsin Streams

  S. Matsumoto; E. Leclerc; T. Maekawa; H. Kinoshita; M. Shinohara; K. Komori; Y. Sakai; T. Fujii

  9th International Symposium on Microchemistry and Microsystems (ISMM 2017), Jun. 2017

  
• 肝細胞培養デバイスにおけるトリプシンを用いた局所的細胞回収方法の検討

  松本倫実; Eric Leclerc; 前川敏郎; 木下晴之; 篠原満利恵; 小森喜久夫; 酒井 康行; 藤井 輝夫

  2017年度精密工学会春季大会, Mar. 2017

  
• Visualization of Oxygen Gradient in a PDMS Hepatocyte Culture Device

  S. Matsumoto; E. Leclerc; T. Maekawa; H. Kinoshita; M. Shinohara; K. Komori; Y. Sakai; T. Fujii

  The 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Oct. 2016

  
• 肝細胞培養マイクロ流体デバイス内での酸素濃度勾配の形成と可視化

  松本倫実; Eric Leclerc; 前川敏郎; 木下晴之; 篠原満利恵; 小森喜久夫; 酒井 康行; 藤井 輝夫

  2016年度生物工学若手研究者の集い夏のセミナー, Jul. 2016

  
• Creation and Visualization of Oxygen Concentration in a Microfluidic Hepatocytes Culture Device

  S. Matsumoto; E. Leclerc; T. Maekawa; H. Kinoshita; M. Shinohara; K. Komori; Y. Sakai; T. Fujii

  8th International Symposium on Microchemistry and Microsystems (ISMM 2016), Jun. 2016

  
• 肝細胞培養マイクロデバイス内における酸素濃度可視化手法の基礎的検証

  松本倫実; Eric Leclerc; 前川敏郎; 木下晴之; 篠原満利恵; 小森喜久夫; 酒井 康行; 藤井 輝夫

  2016年度精密工学会春季大会, Mar. 2016

  
• 肝細胞培養マイクロデバイスにおける酸素濃度勾配の形成

  松本倫実; 前川 敏郎; Eric Leclerc; 酒井 康行; 藤井 輝夫

  第16回計測自動制御学会システムインテグレーション部門講演会, Dec. 2015

  
• Oxygen Gradient Formation in a Microfluidic Cell Culture Device

  S. Matsumoto; E. Leclerc; Y. Sakai; T. Fujii

  9th Nano and Micro Systems International School, Jun. 2015

  
• 聴覚刺激及びリズムの周期性が運動主体感に与える影響の評価

  松本倫実; 濱崎峻資; 前田貴記; 加藤元一郎; 山川博司; 高草木薫; 山下淳; 淺間一

  第23 回ライフサポート学会フロンティア講演会, Feb. 2014

  

Awards

• 09 May 2025

  第32回HAB研究機構学術年会 最優秀ポスター賞
• 29 Oct. 2021

  Vascular Biology 2021 Outstanding Talk Awards for Trainees

External funds: Kakenhi

• Development of a Hepatic Sinusoidal Model for In Vitro Evaluation of Immune-Mediated Drug-Induced Liver Injury

  Grant-in-Aid for Early-Career Scientists

  Basic Section 90110:Biomedical engineering-related

  Kyoto University

  松本 倫実

  From 01 Apr. 2024, To 31 Mar. 2027, Granted

  生体模倣デバイス;薬物性肝障害;マイクロ流体デバイス;肝類洞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K21085/
• Development of a Microphysiological System for Transvascular Drug Delivery to 3D Hepatocyte Spheroids

  Grant-in-Aid for Research Activity Start-up

  0403:Biomedical engineering and related fields

  Kyoto University

  松本 倫実

  From 31 Aug. 2023, To 31 Mar. 2025, Granted

  生体模倣デバイス;肝細胞;血管新生;マイクロ流体デバイス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K19214/
• Development of a retinal organoid disease model using three-dimensional vascular bed

  Fund for the Promotion of Joint International Research (International Collaborative Research)

  Medium-sized Section 28:Nano/micro science and related fields

  Kyoto University

  横川 隆司

  From 09 Sep. 2024, To 31 Mar. 2028, Granted

  ナノマイクロ加工;BioMEMS;ナノマイクロバイオシステム;再生医工学;人工臓器学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24KK0105/

Education

Teaching subject(s)

• From 01 Apr. 2025, To 31 Mar. 2026

  Mechanical and System Engineering Laboratory 3

  5058, Spring, Faculty of Engineering, 1
• From 01 Apr. 2025, To 31 Mar. 2026

  Mechanical and System Engineering Laboratory 3

  5058, Fall, Faculty of Engineering, 1

Academic, Social Contribution

Committee Memberships

• From Mar. 2017, To Oct. 2017

  Young project executive committee member, CHEMINAS