Basic Information

Faculty

• 薬学部

Professional Memberships

• 国際脳循環代謝学会
• 日本微量元素学会
• 薬物動態学会
• 米国核医学会
• 日本核医学会
• 日本薬学会

Academic Degree

• 薬学修士(京都大学)
• 薬学博士(京都大学)

Academic Resume (Graduate Schools)

• 京都大学, 大学院薬学研究科修士課程, 修了

Academic Resume (Undergraduate School/Majors)

• 京都大学, 薬学部製薬化学科, 卒業

Language of Instruction

• English

ID,URL

• J-Global ID

  200901086969738228

researchmap URL

• https://researchmap.jp/read0013284

Research

Research Interests

• 生物無機化学
• 放射性医薬品学
• 病態機能分析学
• 分子イメージング学
• bioinorganic chemistry
• radiopharmaceuitcal sciences
• bioanalytical sciences
• molecular imaging

Research Areas

• Life sciences, Radiology
• Life sciences, Pharmacology

Papers

• Development of anti-HER2 fragment antibody conjugated to iron oxide nanoparticles for in vivo HER2-targeted photoacoustic tumor imaging

  Kengo Kanazaki; Kohei Sano; Akira Makino; Yoichi Shimizu; Fumio Yamauchi; Satoshi Ogawa; Ning Ding; Tetsuya Yano; Takashi Temma; Masahiro Ono; Hideo Saji

  NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, Nov. 2015, Peer-reviewed

  
• In vivo photoacoustic imaging of cancer using indocyanine green-labeled monoclonal antibody targeting the epidermal growth factor receptor

  Kohei Sano; Manami Ohashi; Kengo Kanazaki; Ning Ding; Jun Deguchi; Yuko Kanada; Masahiro Ono; Hideo Saji

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Aug. 2015, Peer-reviewed

  
• Additional information gained by positron emission tomography with Ga-68-DOTATOC for suspected unknown primary or recurrent neuroendocrine tumors

  Yuji Nakamoto; Kohei Sano; Takayoshi Ishimori; Masashi Ueda; Takashi Temma; Hideo Saji; Kaori Togashi

  ANNALS OF NUCLEAR MEDICINE, Jul. 2015, Peer-reviewed

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• A high-affinity fluorescent Zn2+ sensor improved by the suppression of pyridine-pyridone tautomerism and its application in living cells

  Masayori Hagimori; Takashi Temma; Naoko Mizuyama; Takuhiro Uto; Yasuchika Yamaguchi; Yoshinori Tominaga; Takahiro Mukai; Hideo Saji

  SENSORS AND ACTUATORS B-CHEMICAL, Jul. 2015, Peer-reviewed

  
• Application of Radioisotopes for Theranostics, a Combination of Diagnostics and Therapy

  Hideo Saji

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Apr. 2015, Peer-reviewed

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• A low-molecular-weight fluorescent sensor with Zn2+ dependent bathochromic shift of emission wavelength and its imaging in living cells

  Masayori Hagimori; Naoko Mizuyama; Yoshinori Tominaga; Takahiro Mukai; Hideo Saji

  DYES AND PIGMENTS, Feb. 2015, Peer-reviewed

  
• Gallium-68-Labeled Anti-HER2 Single-Chain Fv Fragment: Development and In Vivo Monitoring of HER2 Expression

  Masashi Ueda; Hayato Hisada; Takashi Temma; Yoichi Shimizu; Hiroyuki Kimura; Masahiro Ono; Yuji Nakamoto; Kaori Togashi; Hideo Saji

  MOLECULAR IMAGING AND BIOLOGY, Feb. 2015, Peer-reviewed

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• Radiofluorinated probe for PET imaging of fatty acid binding protein 4 in cancer

  Takashi Temma; Kantaro Nishigori; Satoru Onoe; Sotaro Sampei; Ikuo Kimura; Masahiro Ono; Hideo Saji

  NUCLEAR MEDICINE AND BIOLOGY, Feb. 2015, Peer-reviewed

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• Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice

  Masaki Morishita; Yuki Takahashi; Makiya Nishikawa; Kohei Sano; Kana Kato; Takuma Yamashita; Takafumi Imai; Hideo Saji; Yoshinobu Takakura

  JOURNAL OF PHARMACEUTICAL SCIENCES, Feb. 2015, Peer-reviewed

  
• Novel PET/SPECT probes for imaging of tau in alzheimer's disease

  Hiroyuki Watanabe; Masahiro Ono; Hideo Saji

  Scientific World Journal, 2015, Peer-reviewed

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• Synthesis and biological evaluation of I-123-labeled pyridyl benzoxazole derivatives: novel beta-amyloid imaging probes for single-photon emission computed tomography

  Hiroyuki Watanabe; Masahiro Ono; Shimpei Iikuni; Hiroyuki Kimura; Yoko Okamoto; Masafumi Ihara; Hideo Saji

  RSC ADVANCES, 2015, Peer-reviewed

  
• The synthesis of [F-18]pitavastatin as a tracer for hOATP using the Suzuki coupling

  Yusuke Yagi; Hiroyuki Kimura; Kenji Arimitsu; Masahiro Ono; Kazuya Maeda; Hiroyuki Kusuhara; Tetsuya Kajimoto; Yuichi Sugiyama; Hideo Saji

  ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, Peer-reviewed

  
• A Ga-68 complex based on benzofuran scaffold for the detection of beta-amyloid plaques

  Hiroyuki Watanabe; Masahiro Ono; Shimpei Iikuni; Masashi Yoshimura; Kenji Matsumura; Hiroyuki Kimura; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Oct. 2014, Peer-reviewed

  
• Development of a resonant-type microwave reactor and its application to the synthesis of positron emission tomography radiopharmaceuticals

  Hiroyuki Kimura; Yusuke Yagi; Noriyuki Ohneda; Hiro Odajima; Masahiro Ono; Hideo Saji

  JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Oct. 2014, Peer-reviewed

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• Development of human serum albumin conjugated with near-infrared dye for photoacoustic tumor imaging

  Kengo Kanazaki; Kohei Sano; Akira Makino; Atsushi Takahashi; Jun Deguchi; Manami Ohashi; Takashi Temma; Masahiro Ono; Hideo Saji

  JOURNAL OF BIOMEDICAL OPTICS, Sep. 2014, Peer-reviewed

  
• Preclinical evaluation of a novel cyanine dye for tumor imaging with in vivo photoacoustic imaging

  Takashi Temma; Satoru Onoe; Kengo Kanazaki; Masahiro Ono; Hideo Saji

  JOURNAL OF BIOMEDICAL OPTICS, Sep. 2014, Peer-reviewed

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• Investigation of cyanine dyes for in vivo optical imaging of altered mitochondrial membrane potential in tumors

  Satoru Onoe; Takashi Temma; Yoichi Shimizu; Masahiro Ono; Hideo Saji

  CANCER MEDICINE, Aug. 2014, Peer-reviewed

  
• In vivo imaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe

  Yoichi Shimizu; Takashi Temma; Isao Hara; Akira Makino; Naoya Kondo; Ei-ichi Ozeki; Masahiro Ono; Hideo Saji

  CANCER SCIENCE, Aug. 2014, Peer-reviewed

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• Feasibility of Amylin Imaging in Pancreatic Islets with beta-Amyloid Imaging Probes

  Masashi Yoshimura; Masahiro Ono; Hiroyuki Watanabe; Hiroyuki Kimura; Hideo Saji

  SCIENTIFIC REPORTS, Aug. 2014, Peer-reviewed

  
• Synthesis and evaluation of F-18-labeled mitiglinide derivatives as positron emission tomography tracers for beta-cell imaging

  Hiroyuki Kimura; Hirokazu Matsuda; Hiroyuki Fujimoto; Kenji Arimitsu; Kentaro Toyoda; Eri Mukai; Hiroshi Nakamura; Yu Ogawa; Mikako Takagi; Masahiro Ono; Nobuya Inagaki; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY, Jul. 2014, Peer-reviewed

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• Enhancement of Binding Affinity for Amyloid Aggregates by Multivalent Interactions of Tc-99m-Hydroxamamide Complexes

  Shimpei Iikuni; Masahiro Ono; Hiroyuki Watanabe; Kenji Matsumura; Masashi Yoshimura; Naoya Harada; Hiroyuki Kimura; Morio Nakayama; Hideo Saji

  MOLECULAR PHARMACEUTICS, Apr. 2014, Peer-reviewed

  
• Development of a Radioiodinated Triazolopyrimidine Probe for Nuclear Medical Imaging of Fatty Acid Binding Protein 4

  Kantaro Nishigori; Takashi Temma; Satoru Onoe; Sotaro Sampei; Ikuo Kimura; Masahiro Ono; Hideo Saji

  PLOS ONE, Apr. 2014, Peer-reviewed

  
• Smart Near-Infrared Fluorescence Probes with Donor-Acceptor Structure for in Vivo Detection of beta-Amyloid Deposits

  Mengchao Cui; Masahiro Ono; Hiroyuki Watanabe; Hiroyuki Kimura; Boli Liu; Hideo Saji

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Mar. 2014, Peer-reviewed

  
• Synthesis and evaluation of a radioiodinated peptide probe targeting alpha v beta 6 integrin for the detection of pancreatic ductal adenocarcinoma

  Masashi Ueda; Takahiro Fukushima; Kei Ogawa; Hiroyuki Kimura; Masahiro Ono; Takashi Yamaguchi; Yuzuru Ikehara; Hideo Saji

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Mar. 2014, Peer-reviewed

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• A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for tumor imaging

  Kohei Sano; Ryo Masuda; Hayato Hisada; Shinya Oishi; Kenta Shimokawa; Masahiro Ono; Nobutaka Fujii; Hideo Saji; Takahiro Mukai

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Mar. 2014, Peer-reviewed

  
• Synthesis and evaluation of (-)- and (+)-[C-11]galanthamine as PET tracers for cerebral acetylcholinesterase imaging

  Hiroyuki Kimura; Tomoki Kawai; Yoshio Hamashima; Hidekazu Kawashima; Kenji Miura; Yuta Nakaya; Makoto Hirasawa; Kenji Arimitsu; Tetsuya Kajimoto; Yoshiro Ohmomo; Masahiro Ono; Manabu Node; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY, Jan. 2014, Peer-reviewed

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• Micelle-based activatable probe for in vivo near-infrared optical imaging of cancer biomolecules

  Yoichi Shimizu; Takashi Temma; Isao Hara; Akira Makino; Ryo Yamahara; Ei-ichi Ozeki; Masahiro Ono; Hideo Saji

  NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, Jan. 2014, Peer-reviewed

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• Novel radioiodinated 1,3,4-oxadiazole derivatives with improved in vivo properties for SPECT imaging of beta-amyloid plaques

  Hiroyuki Watanabe; Masahiro Ono; Hiroyuki Kimura; Kenji Matsumura; Masashi Yoshimura; Shimpei Iikuni; Yoko Okamoto; Masafumi Ihara; Ryosuke Takahashi; Hideo Saji

  MEDCHEMCOMM, 2014, Peer-reviewed

  
• Radiolabeled probes targeting hypoxia-inducible factor-1-active tumor microenvironments.

  Ueda M; Saji H

  TheScientificWorldJournal, 2014, Peer-reviewed

  
• Development of an Oxygen-Sensitive Degradable Peptide Probe for the Imaging of Hypoxia-Inducible Factor-1-Active Regions in Tumors

  Masashi Ueda; Kei Ogawa; Azusa Miyano; Masahiro Ono; Shinae Kizaka-Kondoh; Hideo Saji

  MOLECULAR IMAGING AND BIOLOGY, Dec. 2013, Peer-reviewed

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• Preparation of Asymmetric Urea Derivatives that Target Prostate-Specific Membrane Antigen for SPECT Imaging

  Naoya Harada; Hiroyuki Kimura; Masahiro Ono; Hideo Saji

  JOURNAL OF MEDICINAL CHEMISTRY, Oct. 2013, Peer-reviewed

  
• Novel design and synthesis of a radioiodinated glycolipid analog as an acceptor substrate for N-acetylglucosaminyltransferase V

  Kenji Arimitsu; Hiroyuki Kimura; Tetsuya Kajimoto; Masahiro Ono; Yoshiro Ohmomo; Masayuki Yamashita; Manabu Node; Hideo Saji

  JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Sep. 2013, Peer-reviewed

  
• Molecular Imaging of beta-Amyloid Plaques with Near-Infrared Boron Dipyrromethane (BODIPY)-Based Fluorescent Probes

  Hiroyuki Watanabe; Masahiro Ono; Kenji Matsumura; Masashi Yoshimura; Hiroyuki Kimura; Hideo Saji

  MOLECULAR IMAGING, Jul. 2013, Peer-reviewed

  
• Development of New Zinc Dithiosemicarbazone Complex for Use as Oral Antidiabetic Agent

  Saori Kadowaki; Masayuki Munekane; Yoji Kitamura; Makoto Hiromura; Shinichiro Kamino; Yutaka Yoshikawa; Hideo Saji; Shuichi Enomoto

  BIOLOGICAL TRACE ELEMENT RESEARCH, Jul. 2013, Peer-reviewed

  
• Synthesis and evaluation of C-11-labeled naphthalene derivative as a novel non-peptidergic probe for the beta-secretase (BACE1) imaging in Alzheimer's disease brain

  Tomoki Kawai; Hidekazu Kawashima; Yuji Kuge; Hideo Saji

  NUCLEAR MEDICINE AND BIOLOGY, Jul. 2013, Peer-reviewed

  
• Synthesis and biological evaluation of novel styryl benzimidazole derivatives as probes for imaging of neurofibrillary tangles in Alzheimer's disease.

  Kenji Matsumura; Masahiro Ono; Masashi Yoshimura; Hiroyuki Kimura; Hiroyuki Watanabe; Yoko Okamoto; Masafumi Ihara; Ryosuke Takahashi; Hideo Saji

  Bioorganic & medicinal chemistry, 01 Jun. 2013, Peer-reviewed

  
• In Vivo Evaluation of a Radiogallium-Labeled Bifunctional Radiopharmaceutical, Ga-DOTA-MN2, for Hypoxic Tumor Imaging

  Kohei Sano; Mayumi Okada; Hayato Hisada; Kenta Shimokawa; Hideo Saji; Minoru Maeda; Takahiro Mukai

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Apr. 2013, Peer-reviewed

  
• Miniaturized antibodies for imaging membrane type-1 matrix metalloproteinase in cancers

  Naoya Kondo; Takashi Temma; Yoichi Shimizu; Hiroyuki Watanabe; Keiichi Higano; Yoko Takagi; Masahiro Ono; Hideo Saji

  CANCER SCIENCE, Apr. 2013, Peer-reviewed

  
• Quantitative imaging of a therapeutic peptide in biological tissue sections by MALDI MS

  Nozomi Takai; Yukari Tanaka; Ayahisa Watanabe; Hideo Saji

  BIOANALYSIS, Mar. 2013, Peer-reviewed

  
• Radioiodinated peptide probe for selective detection of oxidized low density lipoprotein in atherosclerotic plaques

  Kantaro Nishigori; Takashi Temma; Keiko Yoda; Satoru Onoe; Naoya Kondo; Masashi Shiomi; Masahiro Ono; Hideo Saji

  NUCLEAR MEDICINE AND BIOLOGY, Jan. 2013, Peer-reviewed

  
• Visualization and treatment of the HIF-1-active microenvironments in tumors: Drug design and application of oxygen-dependent degradable probes for molecular imaging of HIF-1-active microenvironments

  M. Ueda; H. Saji

  Hypoxia: Causes, Types and Management, 2013, Peer-reviewed

  
• Development of novel 123I-labeled pyridyl benzofuran derivatives for SPECT imaging of β-amyloid plaques in Alzheimer's disease.

  Masahiro Ono; Yan Cheng; Hiroyuki Kimura; Hiroyuki Watanabe; Kenji Matsumura; Masashi Yoshimura; Shimpei Iikuni; Yoko Okamoto; Masafumi Ihara; Ryosuke Takahashi; Hideo Saji

  PloS one, 2013, Peer-reviewed

  
• Structure-activity relationships and in vivo evaluation of quinoxaline derivatives for PET imaging of β-amyloid plaques

  M. Yoshimura; M. Ono; K. Matsumura; H. Watanabe; H. Kimura; M. Cui; Y. Nakamoto; K. Togashi; Y. Okamoto; M. Ihara; R. Takahashi; H. Saji

  ACS Medicinal Chemistry Letters, 2013, Peer-reviewed

  
• Fluorescence ON/OFF switching Zn2+ sensor based on pyridine-pyridone scaffold

  Masayori Hagimori; Takuhiro Uto; Naoko Mizuyama; Takashi Temma; Yasuchika Yamaguchi; Yoshinori Tominaga; Hideo Saji

  Sensors and Actuators, B: Chemical, 2013, Peer-reviewed

  
• Novel F-18-Labeled Benzoxazole Derivatives as Potential Positron Emission Tomography Probes for Imaging of Cerebral beta-Amyloid Plaques in Alzheimer's Disease

  Mengchao Cui; Masahiro Ono; Hiroyuki Kimura; Masashi Ueda; Yuji Nakamoto; Kaori Togashi; Yoko Okamoto; Masafumi Ihara; Ryosuke Takahashi; Boli Liu; Hideo Saji

  JOURNAL OF MEDICINAL CHEMISTRY, Nov. 2012, Peer-reviewed

  
• Synthesis and Evaluation of Novel F-18 Labeled 2-Pyridinylbenzoxazole and 2-Pyridinylbenzothiazole Derivatives as Ligands for Positron Emission Tomography (PET) Imaging of beta-Amyloid Plaques

  Mengchao Cui; Xuedan Wang; Pingrong Yu; Jinming Zhang; Zijing Li; Xiaojun Zhang; Yanping Yang; Masahiro Ono; Hongmei Jia; Hideo Saji; Boli Liu

  JOURNAL OF MEDICINAL CHEMISTRY, Nov. 2012, Peer-reviewed

  
• F-18-Labeled 2-phenylquinoxaline derivatives as potential positron emission tomography probes for in vivo imaging of beta-amyloid plaques

  Pingrong Yu; Mengchao Cui; Xuedan Wang; Xiaojun Zhang; Zijing Li; Yanping Yang; Jianhua Jia; Jinming Zhang; Masahiro Ono; Hideo Saji; Hongmei Jia; Boli Liu

  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, Nov. 2012, Peer-reviewed

  
• Synthesis and biological evaluation of novel oxindole derivatives for imaging neurofibrillary tangles in Alzheimer's disease

  Hiroyuki Watanabe; Masahiro Ono; Hiroyuki Kimura; Kenji Matsumura; Masashi Yoshimura; Yoko Okamoto; Masafumi Ihara; Ryosuke Takahashi; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Sep. 2012, Peer-reviewed

  
• Norepinephrine Transporter Imaging in the Brain of a Rat Model of Depression Using Radioiodinated (2S, alpha S)-2-(alpha-(2-iodophenoxy)benzyl)morpholine

  Naoki Kanegawa; Yasushi Kiyono; Taku Sugitaa; Yuji Kuge; Yasushisa Fujibayasi; Hideo Saji

  MOLECULAR IMAGING, Jul. 2012, Peer-reviewed

  
• Quantitative analysis of pharmaceutical drug distribution in multiple organs by imaging mass spectrometry

  Nozomi Takai; Yukari Tanaka; Kazuhiro Inazawa; Hideo Saji

  RAPID COMMUNICATIONS IN MASS SPECTROMETRY, Jul. 2012, Peer-reviewed

  
• Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery in vivo

  Ikuhiko Nakase; Yusuke Konishi; Masashi Ueda; Hideo Saji; Shiroh Futaki

  JOURNAL OF CONTROLLED RELEASE, Apr. 2012, Peer-reviewed

  
• BODIPY-Based Molecular Probe for Imaging of Cerebral beta-Amyloid Plaques

  Masahiro Ono; Hiroyuki Watanabe; Hiroyuki Kimura; Hideo Saji

  ACS CHEMICAL NEUROSCIENCE, Apr. 2012, Peer-reviewed

  
• Development of Novel Nanocarrier-Based Near-Infrared Optical Probes for In Vivo Tumor Imaging

  Yoichi Shimizu; Takashi Temma; Isao Hara; Ryo Yamahara; Ei-ichi Ozeki; Masahiro Ono; Hideo Saji

  JOURNAL OF FLUORESCENCE, Mar. 2012, Peer-reviewed

  
• A novel bifunctional chelating agent based on bis(hydroxamamide) for 99mTc labeling of polypeptides

  Masahiro Ono; Masatsugu Ohgami; Mamoru Haratake; Hideo Saji; Morio Nakayama

  JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Feb. 2012, Peer-reviewed

  
• In Vivo Visualization of Heterogeneous Intratumoral Distribution of Hypoxia-Inducible Factor-1 alpha Activity by the Fusion of High-Resolution SPECT and Morphological Imaging Tests

  Hirofumi Fujii; Masayuki Yamaguchi; Kazumasa Inoue; Yasuko Mutou; Masashi Ueda; Hideo Saji; Shinae Kizaka-Kondoh; Noriyuki Moriyama; Izumi O. Umeda

  JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 2012, Peer-reviewed

  
• Molecular approaches to the treatment, prophylaxis, and diagnosis of Alzheimer's disease: Novel PET/SPECT imaging probes for diagnosis of Alzheimer's disease

  Masahiro Ono; Hideo Saji

  Journal of Pharmacological Sciences, 2012, Peer-reviewed

  
• Microwave-Assisted Synthesis of Organometallic Complexes of Tc-99m(CO)(3) and Re(CO)(3): Its Application to Radiopharmaceuticals

  Hiroyuki Kimura; Daisuke Mori; Naoya Harada; Masahiro Ono; Yoshiro Ohmomo; Tetsuya Kajimoto; Hidekazu Kawashima; Hideo Saji

  CHEMICAL & PHARMACEUTICAL BULLETIN, Jan. 2012, Peer-reviewed

  
• F-18-Labeled Phenyldiazenyl Benzothiazole for in Vivo Imaging of Neurofibrillary Tangles in Alzheimer's Disease Brains

  Kenji Matsumura; Masahiro Ono; Hiroyuki Kimura; Masashi Ueda; Yuji Nakamoto; Kaori Togashi; Yoko Okamoto; Masafumi Ihara; Ryosuke Takahashi; Hideo Saji

  ACS MEDICINAL CHEMISTRY LETTERS, Jan. 2012, Peer-reviewed

  
• A Pre-targeting Strategy for MR Imaging of Functional Molecules Using Dendritic Gd-Based Contrast Agents

  Kohei Sano; Takashi Temma; Takashi Azuma; Ryusuke Nakai; Michiko Narazaki; Yuji Kuge; Hideo Saji

  MOLECULAR IMAGING AND BIOLOGY, Dec. 2011, Peer-reviewed

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• A dual fluorinated and iodinated radiotracer for PET and SPECT imaging of beta-amyloid plaques in the brain

  Hiroyuki Watanabe; Masahiro Ono; Hiroyuki Kimura; Shinya Kagawa; Ryuichi Nishii; Takeshi Fuchigami; Mamoru Haratake; Morio Nakayama; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Nov. 2011, Peer-reviewed

  
• Evaluation of [I-125]IPOS as a molecular imaging probe for hypoxia-inducible factor-1-active regions in a tumor: Comparison among single-photon emission computed tomography/X-ray computed tomography imaging, autoradiography, and immunohistochemistry

  Masashi Ueda; Takashi Kudo; Yasuko Mutou; Izumi Ogihara Umeda; Azusa Miyano; Kei Ogawa; Masahiro Ono; Hirofumi Fujii; Shinae Kizaka-Kondoh; Masahiro Hiraoka; Hideo Saji

  CANCER SCIENCE, Nov. 2011, Peer-reviewed

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• Effective synthesis of Tc-99m tricarbonyl complexes by microwave heating

  Naoya Harada; Hiroyuki Kimura; Masahiro Ono; Daisuke Mori; Yoshiro Ohmomo; Tetsuya Kajimoto; Hidekazu Kawashima; Hideo Saji

  JOURNAL OF ORGANOMETALLIC CHEMISTRY, Nov. 2011, Peer-reviewed

  
• Development of membrane type-1 matrix metalloproteinase-specific activatable fluorescent probe for malignant tumor detection

  Yoichi Shimizu; Takashi Temma; Kohei Sano; Masahiro Ono; Hideo Saji

  CANCER SCIENCE, Oct. 2011, Peer-reviewed

  
• PET Imaging of Hypoxia-Inducible Factor-1-Active Tumor Cells with Pretargeted Oxygen-Dependent Degradable Streptavidin and a Novel F-18-Labeled Biotin Derivative

  Takashi Kudo; Masashi Ueda; Hiroaki Konishi; Hidekazu Kawashima; Yuji Kuge; Takahiro Mukai; Azusa Miyano; Shotaro Tanaka; Shinae Kizaka-Kondoh; Masahiro Hiraoka; Hideo Saji

  MOLECULAR IMAGING AND BIOLOGY, Oct. 2011, Peer-reviewed

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• Effective encapsulation of a new cationic gadolinium chelate into apoferritin and its evaluation as an MRI contrast agent

  Akira Makino; Hiroshi Harada; Tomohisa Okada; Hiroyuki Kimura; Hiroo Amano; Hideo Saji; Masahiro Hiraoka; Shunsaku Kimura

  NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, Oct. 2011, Peer-reviewed

  
• SYNTHESIS OF FLUORESCENT PYRROLO[3,4-b]QUINOLIZINE DERIVATIVES AND EVALUATION AS A PROTEIN-LABELING PROBE

  Masayori Hagimori; Naoko Mizuyama; Kenichirou Yokota; Osamu Morinaga; Yasuchika Yamaguchi; Hideo Saji; Yoshinori Tominaga

  HETEROCYCLES, Sep. 2011, Peer-reviewed

  
• Phenyldiazenyl benzothiazole derivatives as probes for in vivo imaging of neurofibrillary tangles in Alzheimer's disease brains

  Kenji Matsumura; Masahiro Ono; Shun Hayashi; Hiroyuki Kimura; Yoko Okamoto; Masafumi Ihara; Ryosuke Takahashi; Hiroshi Mori; Hideo Saji

  MEDCHEMCOMM, Jul. 2011, Peer-reviewed

  
• Synthesis and evaluation of a radioiodinated trisaccharide derivative as a synthetic substrate for a sensitive N-acetylglucosaminyltransferase V radioassay

  Takahiro Mukai; Masayori Hagimori; Kenji Arimitsu; Takahiro Katoh; Misa Ukon; Tetsuya Kajimoto; Hiroyuki Kimura; Yasuhiro Magata; Eiji Miyoshi; Naoyuki Taniguchi; Manabu Node; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY, Jul. 2011, Peer-reviewed

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• Novel quinoxaline derivatives for in vivo imaging of beta-amyloid plaques in the brain

  Mengchao Cui; Masahiro Ono; Hiroyuki Kimura; Boli Liu; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jul. 2011, Peer-reviewed

  
• Synthesis and evaluation of benzofuran-2-yl(phenyl)methanone derivatives as ligands for beta-amyloid plaques

  Mengchao Cui; Masahiro Ono; Hiroyuki Kimura; Boli Liu; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY, Jul. 2011, Peer-reviewed

  
• Concise site-specific synthesis of DTPA-peptide conjugates: Application to imaging probes for the chemokine receptor CXCR4

  Ryo Masuda; Shinya Oishi; Hiroaki Ohno; Hiroyuki Kimura; Hideo Saji; Nobutaka Fujii

  BIOORGANIC & MEDICINAL CHEMISTRY, May 2011, Peer-reviewed

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• Rhodanine and Thiohydantoin Derivatives for Detecting Tau Pathology in Alzheimer's Brains

  Masahiro Ono; Shun Hayashi; Kenji Matsumura; Hiroyuki Kimura; Yoko Okamoto; Masafumi Ihara; Ryosuke Takahashi; Hiroshi Mori; Hideo Saji

  ACS CHEMICAL NEUROSCIENCE, May 2011, Peer-reviewed

  
• Gene and protein analysis of brain derived neurotrophic factor expression in relation to neurological recovery induced by an enriched environment in a rat stroke model

  Kenji Hirata; Yuji Kuge; Chiaki Yokota; Akina Harada; Koichi Kokame; Hiroyasu Inoue; Hidekazu Kawashima; Hiroko Hanzawa; Yuji Shono; Hideo Saji; Kazuo Minematsu; Nagara Tamaki

  NEUROSCIENCE LETTERS, May 2011, Peer-reviewed

  
• Synthesis and Structure-Affinity Relationships of Novel Dibenzylideneacetone Derivatives as Probes for beta-Amyloid Plaques

  Mengchao Cui; Masahiro Ono; Hiroyuki Kimura; Boli Liu; Hideo Saji

  JOURNAL OF MEDICINAL CHEMISTRY, Apr. 2011, Peer-reviewed

  
• Novel F-18-Labeled Benzofuran Derivatives with Improved Properties for Positron Emission Tomography (PET) Imaging of beta-Amyloid Plaques in Alzheimer's Brains

  Masahiro Ono; Yan Cheng; Hiroyuki Kimura; Mengchao Cui; Shinya Kagawa; Ryuichi Nishii; Hideo Saji

  JOURNAL OF MEDICINAL CHEMISTRY, Apr. 2011, Peer-reviewed

  
• Ticlopidine-induced hepatotoxicity in a GSH-depleted rat model

  Shinji Shimizu; Ryo Atsumi; Tsunenori Nakazawa; Takashi Izumi; Kenichi Sudo; Osamu Okazaki; Hideo Saji

  ARCHIVES OF TOXICOLOGY, Apr. 2011, Peer-reviewed

  
• Radioiodinated benzimidazole derivatives as single photon emission computed tomography probes for imaging of beta-amyloid plaques in Alzheimer's disease

  Mengchao Cui; Masahiro Ono; Hiroyuki Kimura; Hidekazu Kawashima; Bo Li Liu; Hideo Saji

  NUCLEAR MEDICINE AND BIOLOGY, Apr. 2011, Peer-reviewed

  
• Gene expression associated with an enriched environment after transient focal ischemia

  Yuji Shono; Chiaki Yokota; Yuji Kuge; Shinsuke Kido; Akina Harada; Koichi Kokame; Hiroyasu Inoue; Mariko Hotta; Kenji Hirata; Hideo Saji; Nagara Tamaki; Kazuo Minematsu

  BRAIN RESEARCH, Feb. 2011, Peer-reviewed

  
• Synthesis and biological evaluation of indole-chalcone derivatives as beta-amyloid imaging probe

  Mengchao Cui; Masahiro Ono; Hiroyuki Kimura; Bo Li Liu; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Feb. 2011, Peer-reviewed

  
• A novel small molecule fluorescent sensor for Zn2+ based on pyridine-pyridone scaffold

  Masayori Hagimori; Naoko Mizuyama; Yasuchika Yamaguchi; Hideo Saji; Yoshinori Tominaga

  TALANTA, Feb. 2011, Peer-reviewed

  
• In Vivo Relationship Between Thalamic Nicotinic Acetylcholine Receptor Occupancy Rates and Antiallodynic Effects in a Rat Model of Neuropathic Pain: Persistent Agonist Binding Inhibits the Expression of Antiallodynic Effects

  Masashi Ueda; Yasuhiko Iida; Tomoki Yoneyama; Tomoki Kawai; Mikako Ogawa; Yasuhiro Magata; Hideo Saji

  SYNAPSE, Jan. 2011, Peer-reviewed

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• Alternative synthesis of radioiodinated trisaccharide derivatives, 2-(4-¹²⁵iodophenyl)ethyl 2-acetamido-2-deoxy-β-d-glucopyranosyl- (1→2)-α-d-mannopyranosyl-( 1→6)-β-d-glucopyranoside, and preparation of its analogs having different lengths of

  K. Arimitsu; T. Kajimoto; H. Kimura; M. Ono; M. Ozeki; M. Node; Y. Ohmomo; H. Saji; M. Yamashita

  Heterocycles, 2011, Peer-reviewed

  
• Diphenylpropynone derivatives as probes for imaging beta-amyloid plaques in Alzheimer's brains

  Masahiro Ono; Hiroyuki Watanabe; Rumi Watanabe; Mamoru Haratake; Morio Nakayama; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jan. 2011, Peer-reviewed

  
• Tissue Factor Detection for Selectively Discriminating Unstable Plaques in an Atherosclerotic Rabbit Model

  Takashi Temma; Yuki Ogawa; Yuji Kuge; Seigo Ishino; Nozomi Takai; Kantaro Nishigori; Masashi Shiomi; Masahiro Ono; Hideo Saji

  JOURNAL OF NUCLEAR MEDICINE, Dec. 2010, Peer-reviewed

  
• Imaging with radiolabelled anti-membrane type 1 matrix metalloproteinase (MT1-MMP) antibody: potentials for characterizing atherosclerotic plaques

  Yuji Kuge; Nozomi Takai; Yuki Ogawa; Takashi Temma; Yan Zhao; Kantaro Nishigori; Seigo Ishino; Junko Kamihashi; Yasushi Kiyono; Masashi Shiomi; Hideo Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Nov. 2010, Peer-reviewed

  
• Novel Benzofurans with Tc-99m Complexes as Probes for Imaging Cerebral beta-Amyloid Plaques

  Masahiro Ono; Yasufumi Fuchi; Takeshi Fuchigami; Nobuya Kobashi; Hiroyuki Kimura; Mamoru Haratake; Hideo Saji; Morio Nakayama

  ACS MEDICINAL CHEMISTRY LETTERS, Nov. 2010, Peer-reviewed

  
• Electron-tracking Compton gamma-ray camera for small animal and phantom imaging

  Shigeto Kabuki; Hiroyuki Kimura; Hiroo Amano; Yuji Nakamoto; Hidetoshi Kubo; Kentaro Miuchi; Shunsuke Kurosawa; Michiaki Takahashi; Hidekazu Kawashima; Masashi Ueda; Tomohisa Okada; Atsushi Kubo; Etuso Kunieda; Tadaki Nakahara; Ryota Kohara; Osamu Miyazaki; Tetsuo Nakazawa; Takashi Shirahata; Etsuji Yamamoto; Koichi Ogawa; Kaori Togashi; Hideo Saji; Toru Tanimori

  NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, Nov. 2010, Peer-reviewed

  
• Tc-99m/Re complexes based on flavone and aurone as SPECT probes for imaging cerebral beta-amyloid plaques

  Masahiro Ono; Ryoichi Ikeoka; Hiroyuki Watanabe; Hiroyuki Kimura; Takeshi Fuchigami; Mamoru Haratake; Hideo Saji; Morio Nakayama

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Oct. 2010, Peer-reviewed

  
• Fluorinated Benzofuran Derivatives for PET Imaging of beta-Amyloid Plaques in Alzheimer's Disease Brains

  Yan Cheng; Masahiro Ono; Hiroyuki Kimura; Shinya Kagawa; Ryuichi Nishii; Hidekazu Kawashima; Hideo Sajio

  ACS MEDICINAL CHEMISTRY LETTERS, Oct. 2010, Peer-reviewed

  
• A novel F-18-labeled pyridyl benzofuran derivative for imaging of beta-amyloid plaques in Alzheimer's brains

  Yan Cheng; Masahiro Ono; Hiroyuki Kimura; Shinya Kagawa; Ryuichi Nishii; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Oct. 2010, Peer-reviewed

  
• Synthesis and Evaluation of Novel Chalcone Derivatives with Tc-99m/Re Complexes as Potential Probes for Detection of beta-Amyloid Plaques

  Masahiro Ono; Ryoichi Ikeoka; Hiroyuki Watanbe; Hiroyuki Kimura; Takeshi Fuchigami; Mamoru Haratake; Hideo Saji; Mono Nakayama

  ACS CHEMICAL NEUROSCIENCE, Sep. 2010, Peer-reviewed

  
• Radioimmunodetection of Membrane Type-1 Matrix Metalloproteinase Relevant to Tumor Malignancy with a Pre-targeting Method

  Kohei Sano; Takashi Temma; Yuji Kuge; Takashi Kudo; Junko Kamihashi; Songji Zhao; Hideo Saji

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Sep. 2010, Peer-reviewed

  
• Rapid detection of hypoxia-inducible factor-1-active tumours: pretargeted imaging with a protein degrading in a mechanism similar to hypoxia-inducible factor-1 alpha

  Masashi Ueda; Takashi Kudo; Yuji Kuge; Takahiro Mukai; Shotaro Tanaka; Hiroaki Konishi; Azusa Miyano; Masahiro Ono; Shinae Kizaka-Kondoh; Masahiro Hiraoka; Hideo Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Aug. 2010, Peer-reviewed

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• Synthesis and characterization of novel phenylindoles as potential probes for imaging of beta-amyloid plaques in the brain

  Hiroyuki Watanabe; Masahiro Ono; Mamoru Haratake; Nobuya Kobashi; Hideo Saji; Morio Nakayama

  BIOORGANIC & MEDICINAL CHEMISTRY, Jul. 2010, Peer-reviewed

  
• Development of dual functional SPECT/fluorescent probes for imaging cerebral beta-amyloid plaques

  Masahiro Ono; Manami Ishikawa; Hiroyuki Kimura; Shun Hayashi; Kenji Matsumura; Hiroyuki Watanabe; Yoichi Shimizu; Yan Cheng; Mengchao Cui; Hidekazu Kawashima; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Jul. 2010, Peer-reviewed

  
• A novel strategy to tag matrix metalloproteinases-positive cells for in vivo imaging of invasive and metastatic activity of tumor cells

  Tao Zhao; Hiroshi Harada; Yuji Teramura; Shotaro Tanaka; Satoshi Itasaka; Akiyo Morinibu; Kazumi Shinomiya; Yuxi Zhu; Hirofumi Hanaoka; Hiroo Iwata; Hideo Saji; Masahiro Hiraoka

  JOURNAL OF CONTROLLED RELEASE, May 2010, Peer-reviewed

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• Nicotinic acetylcholine receptors expressed in the ventralposterolateral thalamic nucleus play an important role in anti-allodynic effects

  M. Ueda; Y. Iida; A. Tominaga; T. Yoneyama; M. Ogawa; Y. Magata; H. Nishimura; Y. Kuge; H. Saji

  BRITISH JOURNAL OF PHARMACOLOGY, Mar. 2010, Peer-reviewed

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• Quantification of regional myocardial oxygen metabolism in normal pigs using positron emission tomography with injectable O-15-O-2

  Takashi Temma; Hidehiro Iida; Takuya Hayashi; Noboru Teramoto; Youichiro Ohta; Nobuyuki Kudomi; Hiroshi Watabe; Hideo Saji; Yasuhiro Magata

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Feb. 2010, Peer-reviewed

  
• NIR fluorescent ytterbium compound for in vivo fluorescence molecular imaging

  Kazuki Aita; Takashi Temma; Yuji Kuge; Koh-ichi Seki; Hideo Saji

  LUMINESCENCE, Jan. 2010, Peer-reviewed

  
• Synthesis of a New NIR Fluorescent Nd Complex Labeling Agent

  Kazuki Aita; Takashi Temma; Yoichi Shimizu; Yuji Kuge; Koh-ichi Seki; Hideo Saji

  JOURNAL OF FLUORESCENCE, Jan. 2010, Peer-reviewed

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• Development of molecular probe for molecular imaging

  H. Saji

  Transactions of Japanese Society for Medical and Biological Engineering, 2010, Peer-reviewed

  
• 「近赤外色素含有ポリマーナノ微粒子、及びそれを用いた光音響分子イメージング

  山内文生; 南昌人; 富田佳紀; 湯浅聡; 矢野哲哉; 近藤科江; 森泰生; 志水陽 一; 天満敬; 小野正博; 佐治英郎; 仁田原智; 青木裕之; 伊藤紳三郎

  2010 World Molecular Imaging Congress (2010.9.9), 2010, Peer-reviewed

  
• Preparation and evaluation of Re-186/188-labeled antibody (A7) for radioimmunotherapy with rhenium(I) tricarbonyl core as a chelate site

  Kazuma Ogawa; Hidekazu Kawashima; Seigo Kinuya; Kazuhiro Shiba; Masahisa Onoguchi; Hiroyuki Kimura; Kazuyuki Hashimoto; Akira Odani; Hideo Saji

  ANNALS OF NUCLEAR MEDICINE, Dec. 2009, Peer-reviewed

  
• GLP-1 receptor antagonist as a potential probe for pancreatic beta-cell imaging

  Eri Mukai; Kentaro Toyoda; Hiroyuki Kimura; Hidekazu Kawashima; Hiroyuki Fujimoto; Masashi Ueda; Takashi Temma; Konomu Hirao; Kenji Nagakawa; Hideo Saji; Nobuya Inagaki

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Nov. 2009, Peer-reviewed

  
• Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression

  Yuji Kuge; Naoyuki Obokata; Hiroyuki Kimura; Yumiko Katada; Takashi Temma; Yukihiko Sugimoto; Kazuki Aita; Koh-ichi Seki; Nagara Tamaki; Hideo Saji

  NUCLEAR MEDICINE AND BIOLOGY, Nov. 2009, Peer-reviewed

  
• Fluoro-pegylated Chalcones as Positron Emission Tomography Probes for in Vivo Imaging of beta-Amyloid Plaques in Alzheimer's Disease

  Masahiro Ono; Rumi Watanabe; Hidekazu Kawashima; Yan Cheng; Hiroyuki Kimura; Hiroyuki Watanabe; Mamoru Haratake; Hideo Saji; Morio Nakayama

  JOURNAL OF MEDICINAL CHEMISTRY, Oct. 2009, Peer-reviewed

  
• Push-pull benzothiazole derivatives as probes for detecting beta-amyloid plaques in Alzheimer's brains

  Masahiro Ono; Shun Hayashi; Hiroyuki Kimura; Hidekazu Kawashima; Morio Nakayama; Hideo Saji

  BIOORGANIC & MEDICINAL CHEMISTRY, Oct. 2009, Peer-reviewed

  
• Synthesis and biological evaluation of radioiodinated 2,5-diphenyl-1,3,4-oxadiazoles for detecting beta-amyloid plaques in the brain

  Hiroyuki Watanabe; Masahiro Ono; Ryoichi Ikeoka; Mamoru Haratake; Hideo Saji; Morio Nakayama

  BIOORGANIC & MEDICINAL CHEMISTRY, Sep. 2009, Peer-reviewed

  
• Development of a Radiolabeled Probe for Detecting Membrane Type-1 Matrix Metalloproteinase on Malignant Tumors

  Takashi Temma; Kohei Sano; Yuji Kuge; Junko Kamihashi; Nozomi Takai; Yuki Ogawa; Hideo Saji

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Jul. 2009, Peer-reviewed

  
• Imaging of HIF-1-Active Tumor Hypoxia Using a Protein Effectively Delivered to and Specifically Stabilized in HIF-1-Active Tumor Cells

  Takashi Kudo; Masashi Ueda; Yuji Kuge; Takahiro Mukai; Shotaro Tanaka; Maki Masutani; Yasushi Kiyono; Shinae Kizaka-Kondoh; Masahiro Hiraoka; Hideo Saji

  JOURNAL OF NUCLEAR MEDICINE, Jun. 2009, Peer-reviewed

  
• F-18-labeled flavones for in vivo imaging of beta-amyloid plaques in Alzheimer's brains

  Masahiro Ono; Rumi Watanabe; Hidekazu Kawashima; Tomoki Kawai; Hiroyuki Watanabe; Mamoru Haratake; Hideo Saji; Morio Nakayama

  BIOORGANIC & MEDICINAL CHEMISTRY, Mar. 2009, Peer-reviewed

  
• Central in Vivo Nicotinic Acetylcholine Receptor Imaging Agents for Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT)

  Mikako Ogawa; Hideo Tsukada; Kentaro Hatano; Yasuomi Ouchi; Hideo Saji; Yasuhiro Magata

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Mar. 2009, Peer-reviewed

  
• Development of [Y-90]DOTA-conjugated bisphosphonate for treatment of painful bone metastases

  Kazuma Ogawa; Hidekazu Kawashima; Kazuhiro Shiba; Kohshin Washiyama; Mitsuyoshi Yoshimoto; Yasushi Kiyono; Masashi Ueda; Hirofumi Mori; Hideo Saji

  NUCLEAR MEDICINE AND BIOLOGY, Feb. 2009, Peer-reviewed

  
• Novel Radioiodinated Aurones as Probes for SPECT Imaging of beta-Amyloid Plaques in the Brain

  Yoshifumi Maya; Masahiro Ono; Hiroyuki Watanabe; Mamoru Haratake; Hideo Saji; Morio Nakayama

  BIOCONJUGATE CHEMISTRY, Jan. 2009, Peer-reviewed

  
• Molecular imaging for acceleration of drug discovery & development and innovation of clinical diagnosis and therapy

  H. Saji; K. Kikuchi

  Yakugaku Zasshi, 2009, Peer-reviewed

  
• Usefulness of competitive inhibitors of protein binding for improving the pharmacokinetics of (186)Re-MAG3-conjugated bisphosphonate ((186)Re-MAG3-HBP), an agent for treatment of painful bone metastases

  Kazuma Ogawa; Takahiro Mukai; Keiichi Kawai; Norito Takamura; Hirofumi Hanaoka; Kazuyuki Hashimoto; Kazuhiro Shiba; Hirofumi Mori; Hideo Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Jan. 2009, Peer-reviewed

  
• Targeting of Lectinlike Oxidized Low-Density Lipoprotein Receptor 1 (LOX-1) with (99m)TCLabeled Anti-LOX-1 Antibody: Potential Agent for Imaging of Vulnerable Plaque

  Seigo Ishino; Takahiro Mukai; Yuji Kuge; Noriaki Kume; Mikako Ogawa; Nozomi Takai; Junko Kamihashi; Masashi Shiomi; Manabu Minami; Toru Kita; Hideo Saji

  JOURNAL OF NUCLEAR MEDICINE, Oct. 2008, Peer-reviewed

  
• Cardioprotective Effects of Erythropoietin in Rats Subjected to Ischemia-Reperfusion Injury: Assessment of Infarct Size with Tc-99m-Annexin V

  Tomoki Done; Katsuichi Ohtsuki; Kazuma Ogawa; Masashi Ueda; Akihiro Azumal; Hideo Saji; Harry W. Strauss; Hiroaki Matsubara

  JOURNAL OF NUCLEAR MEDICINE, Oct. 2008, Peer-reviewed

  
• Prominent lectin-like oxidized low density lipoprotein (LDL) receptor-1 (LOX-1) expression in atherosclerotic lesions is associated with tissue factor expression and apoptosis in hypercholesterolemic rabbits

  Yuji Kuge; Noriaki Kume; Scigo Ishino; Nozomi Takai; Yuki Ogawa; Takahiro Mukai; Manabu Minami; Masashi Shiomi; Hideo Saji

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Aug. 2008, Peer-reviewed

  
• Development of novel β-amyloid probes based on 3,5-diphenyl-1,2,4-oxadiazole

  Masahiro Ono; Mamoru Haratake; Hideo Saji; Morio Nakayama

  Bioorganic and Medicinal Chemistry, 15 Jul. 2008, Peer-reviewed

  
• PET 0-15 cerebral blood flow and metabolism after acute stroke in spontaneously hypertensive rats

  Takashi Temma; Yuji Kuge; Kohei Sano; Junko Kamihashi; Naoyuki Obokata; Hidekazu Kawashima; Yasuhiro Magata; Hideo Saji

  BRAIN RESEARCH, May 2008, Peer-reviewed

  
• CYP2D6-mediated metabolism of a novel acyl coenzyme A: Cholesterol acyltransferase inhibitor, pactimibe, and its unique plasma metabolite, R-125528

  Masakatsu Kotsuma; Taro Tokui; Tomoko Ishizuka-Ozeki; Tomoyo Honda; Haruo Iwabuchi; Takahiro Murai; Toshihiko Ikeda; Hideo Saji

  DRUG METABOLISM AND DISPOSITION, Mar. 2008, Peer-reviewed

  
• Application of radiometallic compounds for medical diagnosis and therapy

  Hideo Saji

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Mar. 2008, Peer-reviewed

  
• 5-Iodo-A-85380, a specific ligand for alpha A beta 2 nicotinic acetylcholine receptors, prevents glutamate neurotoxicity in rat cortical cultured neurons

  Masashi Ueda; Yasuhiko Iida; Youji Kitamura; Hidekazu Kawashima; Mikako Ogawa; Yasuhiro Mayata; Hideo Saji

  BRAIN RESEARCH, Mar. 2008, Peer-reviewed

  
• Evaluation of radioiodinated (2S,alpha S)-2-(alpha-(2-iodophenoxy)benzyl) morpholine as a radioligand for imaging of norepinephrine transporter in the heart

  Yasushi Kiyono; Taku Sugita; Masashi Ueda; Hidekazu Kawashima; Naoki Kanegawa; Yuji Kuge; Yasuhisa Fujibayashi; Hideo Saji

  NUCLEAR MEDICINE AND BIOLOGY, Feb. 2008, Peer-reviewed

  
• Influence of various combinations of mucolytic agent and non-ionic surfactant on intestinal absorption of poorly absorbed hydrophilic compounds

  Shinya Takatsuka; Takahiro Morita; Yuji Horikiri; Hiroshi Yamahara; Hideo Saji

  INTERNATIONAL JOURNAL OF PHARMACEUTICS, Feb. 2008, Peer-reviewed

  
• Temporal change in human nicotinic acetylcholine receptor after smoking cessation: 5IA SPECT study

  Marcelo Mamedel; Koichi Ishizu; Masashi Ueda; Takahiro Mukail; Yasuhiko Lida; Hidekazu Kawashima; Hidenao Fukuyama; Kaori Togashil; Hideo Saji

  JOURNAL OF NUCLEAR MEDICINE, Nov. 2007, Peer-reviewed

  
• Effect of carboxyl-group of D-glutamic acid or gamma-carboxy-D-glutamic acid as N-terminal amino acid of In-111-diethylenetriaminepentaacetic acid-octreotide on accumulation of radioactivity in kidney

  Hiromichi Akizawa; Madoka Saito; Ikuko Tsukamoto; Tatsuya Ohkura; Takaya Shimizu; Youji Kitamura; Masaki Mifune; Yutaka Saito; Yasushi Arano; Hideo Saji

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Nov. 2007, Peer-reviewed

  
• Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with atherosclerotic plaque instability-analysis in hypercholesterolemic rabbits

  Seigo Ishino; Takahiro Mukai; Noriaki Kume; Daigo Asano; Mikako Ogawa; Yuji Kuge; Manabu Minami; Toru Kita; Masashi Shiomi; Hideo Saji

  ATHEROSCLEROSIS, Nov. 2007, Peer-reviewed

  
• Development of a novel neodymium compound for in vivo fluorescence imaging

  Kazuki Aita; Takashi Temma; Yuji Kuge; Hideo Saji

  LUMINESCENCE, Sep. 2007, Peer-reviewed

  
• Distribution profiles of membrane type-1 matrix metalloproteinase (MT1-MMP), matrix metalloproteinase-2 (MMP-2) and cyclooxygenase-2 (COX-2) in rabbit atherosclerosis: Comparison with plaque instability analysis

  Yuji Kuge; Nozomi Takai; Seigo Ishino; Takashi Temma; Masashi Shiomi; Hideo Saji

  Biological and Pharmaceutical Bulletin, Sep. 2007, Peer-reviewed

  
• Applicability of a high-resolution small semiconductor gamma camera to small animal imaging

  Yasushi Kiyono; Yuji Kuge; Yumiko Katada; Hidekazu Kawashima; Yasuhiro Magata; Hideo Saji

  NUCLEAR MEDICINE COMMUNICATIONS, Sep. 2007, Peer-reviewed

  
• Chemical design of a radiolabeled gelatinase inhibitor peptide for the imaging of gelatinase activity in tumors

  Hirofurni Hanaoka; Takahiro Mukai; Sayo Habashita; Daigo Asano; Kazuina Ogawa; Yoshihiro Kuroda; Hiromichi Akizawa; Yasuhiko Iida; Keigo Endo; Tsuneo Saga; Hideo Saji

  NUCLEAR MEDICINE AND BIOLOGY, Jul. 2007, Peer-reviewed

  
• Tc-99m-Annexin A5 for noninvasive characterization of atherosclerotic lesions: imaging and histological studies in myocardial infarction-prone Watanabe heritable hyperlipidemic rabbits

  Seigo Ishino; Yuji Kuge; Nozomi Takai; Nagara Tamaki; H. William Strauss; Francis G. Blankenberg; Masashi Shiomi; Hideo Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Jun. 2007, Peer-reviewed

  
• Absorption enhancement of poorly absorbed hydrophilic compounds from various mucosal sites by combination of mucolytic agent and non-ionic surfactant

  Shinya Takatsuka; Takahiro Morita; Yuji Horikiri; Hiroshi Yamahara; Hideo Saji

  INTERNATIONAL JOURNAL OF PHARMACEUTICS, Jun. 2007, Peer-reviewed

  
• Quantification of nicotinic acetylcholine receptors in Parkinson's disease with I-123-5IA SPECT

  Naoya Oishi; Kazuo Hashikawa; Hidefumi Yoshida; Koichi Ishizu; Masashi Ueda; Hidekazu Kawashima; Hideo Saji; Hidenao Fukuyama

  JOURNAL OF THE NEUROLOGICAL SCIENCES, May 2007, Peer-reviewed

  
• Is MIBG a substrate of P-glycoprotein?

  Yasushi Kiyono; Tomoko Yamashita; Hisako Doi; Yuji Kuge; Toshiya Katsura; Ken-Ichi Inui; Hideo Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Apr. 2007, Peer-reviewed

  
• Molecular imaging in evaluation of in vivo behavior of drugs

  H. Saji

  Nippon rinsho. Japanese journal of clinical medicine, 2007, Peer-reviewed

  
• Therapeutic effects of a (186) Re-complex-conjugated bisphosphonate for the palliation of metastatic bone pain in an animal model

  Kazuma Ogawa; Takahiro Mukai; Daigo Asano; Hidekazu Kawashima; Seigo Kinuya; Kazuhiro Shiba; Kazuyuki Hashimoto; Hirofumi Mori; Hideo Saji

  JOURNAL OF NUCLEAR MEDICINE, Jan. 2007, Peer-reviewed

  
• 放射性物質濃度測定の全学実施体制について

  加藤隆久; 宮武秀男; 石塚史彦; 戸崎充男; 倉橋和義; 川本卓男; 佐治英郎

  日本放射線安全管理学会誌. 2007; 6(2):9, 2007, Peer-reviewed

  
• Development of a novel 99mTc-chelate-conjugated bisphosphonate with high affinity for bone as a bone scintigraphic agent

  Kazuma Ogawa; Takahiro Mukai; Yasuyuki Inoue; Masahiro Ono; Hideo Saji

  Journal of Nuclear Medicine, 01 Dec. 2006, Peer-reviewed

  
• Estimation of oxygen metabolism in a rat model of permanent ischemia using positron emission tomography with injectable O-15-O-2

  Takashi Temma; Yasuhiro Magata; Yuji Kuge; Sayaka Shimonaka; Kohei Sano; Yumiko Katada; Hidekazu Kawashima; Takahiro Mukai; Hiroshi Watabe; Hidehiro Iida; Hideo Saji

  JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Dec. 2006, Peer-reviewed

  
• Application of F-18-FDG PET for monitoring the therapeutic effect of antiinflammatory drugs on stabilization of vulnerable atherosclerotic plaques

  Mikako Ogawa; Yasuhiro Magata; Takashi Kato; Kentaro Hatano; Seigo Ishino; Takahiro Mukai; Masashi Shiomi; Kengo Ito; Hideo Saji

  JOURNAL OF NUCLEAR MEDICINE, Nov. 2006, Peer-reviewed

  
• Synthesis and evaluation of radioiodinated (S,S)-2-(alpha-(2-iodophenoxy)benzyl)morpholine for imaging brain norepinephrine transporter

  Naoki Kanegawa; Yasushi Kiyono; Hiroyuki Kimura; Taku Sugita; Satomi Kajiyama; Hidekazu Kawashima; Masashi Ueda; Yuji Kuge; Hideo Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Jun. 2006, Peer-reviewed

  
• A catheter-based intravascular radiation detector of vulnerable plaques

  R Hosokawa; N Kambara; M Ohba; T Mukai; M Ogawa; H Motomura; N Kume; H Saji; T Kita; R Nohara

  JOURNAL OF NUCLEAR MEDICINE, May 2006, Peer-reviewed

  
• Release of vesicular Zn2+ in a rat transient middle cerebral artery occlusion model

  Youji Kitamura; Yasuhiko Lida; Jun Abe; Masaki Mifune; Fumiyo Kasuya; Masayuki Ohta; Kazuo Igarashi; Yutaka Saito; Hideo Saji

  BRAIN RESEARCH BULLETIN, May 2006, Peer-reviewed

  
• Development of a In-111-labeled peptide derivative targeting a chemokine receptor, CXCR4, for imaging tumors

  H Hanaoka; T Mukai; H Tamamura; T Mori; S Ishino; K Ogawa; Y Iida; R Doi; N Fujii; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, May 2006, Peer-reviewed

  
• Rhemium-186-monoaminemonoamidedithiol-conjugated bisphosphonate derivatives for bone pain palliation

  Kazuma Ogawa; Takahiro Mukai; Yasushi Arano; Akira Otaka; Masashi Ueda; Tomoya Uebara; Yasuhiro Magata; Kazuyuki Hashimoto; Hideo Saji

  NUCLEAR MEDICINE AND BIOLOGY, May 2006, Peer-reviewed

  
• Novel benzofuran derivatives for PET imaging of beta-amyloid plaques in Alzheimer's disease brains

  M Ono; H Kawashima; A Nonaka; T Kawai; M Haratake; H Mori; MP Kung; HF Kung; H Saji; M Nakayama

  JOURNAL OF MEDICINAL CHEMISTRY, May 2006, Peer-reviewed

  
• Detection of maleate-induced Fanconi syndrome by decreasing accumulation of I-125-3-iodo-alpha-methyl-L-tyrosine in the proximal tubule segment-1 region of renal cortex in mice: a trial of separate evaluation of reabsorption

  N Shikano; S Nakajima; T Kotani; Y Itoh; R Nishii; M Yoshimoto; LG Flores; H Saji; N Ishikawa; K Kawai

  ANNALS OF NUCLEAR MEDICINE, Apr. 2006, Peer-reviewed

  
• In vivo measurement of presynaptic Zn2+ release during forebrain ischemia in rats

  Y Kitamura; Y Iida; J Abe; M Mifune; F Kasuya; M Ohta; K Igarashi; Y Saito; H Saji

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Apr. 2006, Peer-reviewed

  
• Change of central cholinergic receptors following lesions of nucleus basalis magnocellularis in rats: search for an imaging index suitable for the early detection of Alzheimer's disease

  M Ogawa; Y Iida; M Nakagawa; Y Kuge; H Kawashima; A Tominaga; M Ueda; Y Magata; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Feb. 2006, Peer-reviewed

  
• Protective effect of zinc against ischemic neuronal injury in a middle cerebral artery occlusion model

  Y Kitamura; Y Iida; J Abe; M Ueda; M Mifune; F Kasuya; M Ohta; K Igarashi; Y Saito; H Saji

  JOURNAL OF PHARMACOLOGICAL SCIENCES, Feb. 2006, Peer-reviewed

  
• Reduced I-125-meta-iodobenzylguanidine uptake and norepinephrine transporter density in the hearts of mice with MPTP-induced parkinsonism

  N Fukumitsu; M Suzuki; T Fukuda; Y Kiyono; S Kajiyama; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Jan. 2006, Peer-reviewed

  
• Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression

  Y Kuge; Y Katada; S Shimonaka; T Temma; H Kimura; Y Kiyono; C Yokota; K Minematsu; K Seki; N Tamaki; K Ohkura; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Jan. 2006, Peer-reviewed

  
• Alteration of striatal [C-11]raclopride and 6-[F-18]fluoro-L-3,4-dihydroxyphenylalanine uptake precedes development of methamphetamine-induced rotation following unilateral 6-hydroxydopamine lesions of medial forebrain bundle in rats

  Y Ishida; K Kawai; Y Magata; H Abe; M Yoshimoto; R Takeda; H Hashiguchi; T Mukai; H Saji

  NEUROSCIENCE LETTERS, Nov. 2005, Peer-reviewed

  
• In vitro system to estimate renal brush border enzyme-mediated cleavage of peptide linkages for designing radiolabeled antibody fragments of low renal radioactivity levels

  Y Fujioka; S Satake; T Uehara; T Mukai; H Akizawa; K Ogawa; H Saji; K Endo; Y Arano

  BIOCONJUGATE CHEMISTRY, Nov. 2005, Peer-reviewed

  
• Erratum: Influence of the polyol pathway on norepinephrine transporter reduction in diabetic cardiac sympathetic nerves: Implications for heterogeneous accumulation of MIBG (European Journal of Nuclear Medicine and Molecular Imaging DOI: 10.1007/s00259-004-1694-7)

  Yasushi Kiyono; Satomi Kajiyama; Hiromi Fujiwara; Naoki Kanegawa; Hideo Saji

  European Journal of Nuclear Medicine and Molecular Imaging, Aug. 2005, Peer-reviewed

  
• Development of a rhenium-186-labeled MAG3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals

  K Ogawa; T Mukai; Y Arano; M Ono; H Hanaoka; S Ishino; K Hashimoto; H Nishimura; H Saji

  BIOCONJUGATE CHEMISTRY, Jul. 2005, Peer-reviewed

  
• Influence of the polyol pathway on norepinephrine transporter reduction in diabetic cardiac sympathetic nerves: implications for heterogeneous accumulation of MIBG

  Y Kiyono; S Kajiyama; H Fujiwara; N Kanegawa; H Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Apr. 2005, Peer-reviewed

  
• Basic characterization of Cu-64-ATSM as a radiotherapy agent

  A Obata; S Kasamatsu; JS Lewis; T Furukawa; S Takamatsu; J Toyohara; T Asai; MJ Welch; SG Adams; H Saji; Y Yonekura; Y Fujibayashi

  NUCLEAR MEDICINE AND BIOLOGY, Jan. 2005, Peer-reviewed

  
• Synthesis and evaluation of fluorine-substituted 1H-pyrrolo[2,3-b]pyridine derivatives for dopamine D-4 receptor imaging

  SJ Oh; KC Lee; SY Lee; EK Ryu; H Saji; YS Choe; DY Chi; SE Kim; J Lee; BT Kim

  BIOORGANIC & MEDICINAL CHEMISTRY, Nov. 2004, Peer-reviewed

  
• Sensory stimulation accelerates dopamine release in the basal ganglia

  M Inoue; Y Katsumi; T Hayashi; B Mukai; K Ishizu; K Hashikawa; H Saji; H Fukuyama

  BRAIN RESEARCH, Nov. 2004, Peer-reviewed

  
• Design of a radiopharmaceutical for the palliation of painful bone metastases: rhenium-186-labeled bisphosphonate derivative

  K Ogawa; T Mukai; Y Arano; H Hanaoka; K Hashimoto; H Nishimura; H Saji

  JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Oct. 2004, Peer-reviewed

  
• Quantification of human nicotinic acetylcholine receptors with 123I-5IA SPECT

  M Mamede; K Ishizu; M Ueda; T Mukai; Y Iida; H Fukuyama; T Saga; H Saji

  JOURNAL OF NUCLEAR MEDICINE, Sep. 2004, Peer-reviewed

  
• A catheter-based radiation detector for endovascular detection of atheromatous plaques

  T Mukai; R Nohara; M Ogawa; S Ishino; N Kambara; K Kataoka; T Kanoi; K Saito; H Motomura; J Konishi; H Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Sep. 2004, Peer-reviewed

  
• Availability of N-isopropyl-p-[(125)I]iodoamphetamine (IMP) as a practical cerebral blood flow (CBF) indicator in rats

  T Temma; Y Magata; T Mukai; H Kitano; J Konishi; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Aug. 2004, Peer-reviewed

  
• (18)F-FDG accumulation in atherosclerotic plaques: Immunohistochemical and PET imaging study

  M Ogawa; S Ishino; T Mukai; D Asano; N Teramoto; H Watabe; N Kudomi; M Shiomi; Y Magata; H Iida; H Saji

  JOURNAL OF NUCLEAR MEDICINE, Jul. 2004, Peer-reviewed

  
• 5-[I-123]iodo-A-85380: assessment of pharmacological safety, radiation dosimetry and SPECT imaging of brain nicotinic receptors in healthy human subjects

  M Ueda; Y Iida; T Mukai; M Mamede; K Ishizu; M Ogawa; Y Magata; J Konishi; H Saji

  ANNALS OF NUCLEAR MEDICINE, Jun. 2004, Peer-reviewed

  
• Renal accumulation and excretion of radioiodinated 3-iodo-alpha-methyl-L-tyrosine

  N Shikano; K Kawai; S Nakajima; R Nishii; LG Flores; A Kubodera; N Kubota; N Ishikawa; H Saji

  ANNALS OF NUCLEAR MEDICINE, May 2004, Peer-reviewed

  
• Transcellular transport of radioiodinated 3-iodo-alpha-methyl-L-tyrosine across monolayers of kidney epithelial cell line LLC-PK1

  N Shikano; K Kawai; S Nakajima; A Kubodera; N Kubota; N Ishikawa; H Saji

  ANNALS OF NUCLEAR MEDICINE, May 2004, Peer-reviewed

  
• Evaluation of 5-(11)C-methyl-A-85380 as an imaging agent for PET invesvigations of brain nicotinic acetylcholine receptors

  Y Iida; M Ogawa; M Ueda; A Tominaga; H Kawashima; Y Magata; S Nishiyama; H Tsukada; T Mukai; H Saji

  JOURNAL OF NUCLEAR MEDICINE, May 2004, Peer-reviewed

  
• Transcellular transport of 4-iodo-L-meta-tyrosine via system L across monolayers of kidney epithelial cell Line LLC-PK1

  N Shikano; K Kawai; S Nakajima; A Kubodera; N Kubota; N Ishikawa; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, May 2004, Peer-reviewed

  
• A Tc-99m-labeled long chain fatty acid derivative for myocardial imaging

  Y Magata; T Kawaguchi; M Ukon; N Yamamura; T Uehara; K Ogawa; Y Arano; T Temma; T Mukai; E Tadamura; H Saji

  BIOCONJUGATE CHEMISTRY, Mar. 2004, Peer-reviewed

  
• Skeletal affinity of Tc(V)-DMS is bone cell mediated and pH dependent

  K Horiuchi-Suzuki; A Konno; M Ueda; Y Fukuda; S Nishio; K Hashimoto; H Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Mar. 2004, Peer-reviewed

  
• Evaluation of radioiodinated (R)-N-methyl-3-(2-iodophenoxy)-3-phenylpropanamine as a ligand for brain norepinephrine transporter imaging

  Y Kiyono; N Kanegawa; H Kawashima; Y Kitamura; Y Iida; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Feb. 2004, Peer-reviewed

  
• Effect of carboxylation of N-terminal phenylalanine of In-111-DTPA (diethylenetriaminepentaacetic acid)octreotide on accumulation of radioactivity in kidney

  H Akizawa; H Takimoto; M Saito; A Iwado; M Mifune; Y Saito; T Uehara; Y Arano; T Mukai; H Hanaoka; H Saji

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Feb. 2004, Peer-reviewed

  
• Changes in Dopamine D-2 Receptors and 6-[F-18]Fluoro-L-3,4-Dihydroxyphenylalanine Uptake in the Brain of 6-Hydroxydopamine-Lesioned Rats

  Yasushi Ishida; Keiichi Kawai; Yasuhiro Magata; Ryuichiro Takeda; Hiroyuki Hashiguchi; Hiroshi Abe; Takahiro Mukai; Hideo Saji

  NEURODEGENERATIVE DISEASES, 2004, Peer-reviewed

  
• What is the source of the skeletal affinity of ^99mTc-V-DMSA?

  T. Athanasoulis; J. Koutsikos; C. Zerva; K. Horiuchi-Suzuki; H. Saji; H. Ohta

  European Journal of Nuclear Medicine and Molecular Imaging, 2004, Peer-reviewed

  
• Binding of 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4 oxobutyl]pyridinium ion (HPP+), a metabolite of haloperidol, to synthetic melanin: Implications for the dopaminergic neurotoxicity of HPP+

  H Kawashima; Y Iida; Y Kitamura; H Saji

  NEUROTOXICITY RESEARCH, 2004, Peer-reviewed

  
• A new norepinephrine transporter imaging agent for cardiac sympathetic nervous function imaging: radioiodinated (R)-N-methyl-3(2-iodophenoxy)-3-phenylpropanamine

  Y Kiyono; N Kanegawa; H Kawashima; H Fujiwara; Y Iida; H Nishimura; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Oct. 2003, Peer-reviewed

  
• Recovery of motor function and dopaminergic parameters in a mouse model of Parkinson's disease induced by co-administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and diethyldithiocarbamate

  S Shimazu; K Takahata; A Tamashiro; F Yoneda; Y Iida; H Saji

  JOURNAL OF NEURAL TRANSMISSION, Aug. 2003, Peer-reviewed

  
• Effects of monoamine oxidase inhibitors on the diethyldithiocarbamate-induced enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in C57BL/6 mice

  K Takahata; S Shimazu; F Yoneda; M Ogawa; Y Iida; H Saji

  JOURNAL OF NEURAL TRANSMISSION, Aug. 2003, Peer-reviewed

  
• Design of radiolabeled antibody fragments for tumor-selective radioactivity localization-brush border enzyme-sensitive bond to decrease renal accumulation of radioactivity

  T Mukai; Y Fujioka; Y Arano; H Saji

  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Aug. 2003, Peer-reviewed

  
• Production of therapeutic quantities of Cu-64 using a 12 MeV cyclotron

  A Obata; S Kasamatsu; DW McCarthy; MJ Welch; H Saji; Y Yonekura; Y Fujibayashi

  NUCLEAR MEDICINE AND BIOLOGY, Jul. 2003, Peer-reviewed

  
• Intra-tumoral distribution of Cu-64-ATSM: A comparison study with FDG

  A Obata; M Yoshimoto; S Kasamatsu; H Naiki; S Takamatsu; K Kashikura; T Furukawa; JS Lewis; MJ Welch; H Saji; Y Yonekura; Y Fujibayashi

  NUCLEAR MEDICINE AND BIOLOGY, Jul. 2003, Peer-reviewed

  
• Development of injectable O-15 oxygen and estimation of rat OEF

  Y Magata; T Temma; T Iida; M Ogawa; T Mukai; T Iida; T Morimoto; J Konishi; H Saji

  JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Jun. 2003, Peer-reviewed

  
• Simple analytic method of (11)C-flumazenil metabolite in blood

  Y Magata; T Mukai; M Ihara; S Nishizawa; H Kitano; K Ishizu; H Saji; J Konishi

  JOURNAL OF NUCLEAR MEDICINE, Mar. 2003, Peer-reviewed

  
• In vivo imaging of brain dopaminergic neurotransmission system in small animals with high-resolution single photon emission computed tomography

  H Saji; Y Iida; H Kawashima; M Ogawa; Y Kitamura; T Mukai; S Shimazu; F Yoneda

  ANALYTICAL SCIENCES, Jan. 2003, Peer-reviewed

  
• Direct electrophilic radiofluorination of a cyclic RGD peptide for in vivo alpha(v)beta(3) integrin related tumor imaging

  M Ogawa; K Hatano; S Oishi; Y Kawasumi; N Fujii; M Kawaguchi; R Doi; M Imamura; M Yamamoto; K Ajito; T Mukai; H Saji; K Ito

  NUCLEAR MEDICINE AND BIOLOGY, Jan. 2003, Peer-reviewed

  
• Quantification in SPECT cardiac imaging

  H Iida; T Hayashi; S Eberl; H Saji

  JOURNAL OF NUCLEAR MEDICINE, Jan. 2003, Peer-reviewed

  
• Biomedical imaging in pharmacology with nuclear medical imaging methodologies: Positron emission tomography (PET) and single photon emission computed tomography (SPECT)

  Hideo Saji; Yasuhiko Iida

  Folia Pharmacologica Japonica, 2003, Peer-reviewed

  
• Norepinephrine transporter density as a causative factor in alterations in MIBG myocardial uptake in NIDDM model rats

  Y Kiyono; Y Iida; H Kawashima; M Ogawa; N Tamaki; H Nishimura; H Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, Aug. 2002, Peer-reviewed

  
• Synthesis and evaluation of a monoreactive DOTA derivative for indium-111-based residualizing label to estimate protein pharmacokinetics

  T Mukai; S Namba; Y Arano; M Ono; Y Fujioka; T Uehara; K Ogawa; J Konishi; H Saji

  JOURNAL OF PHARMACY AND PHARMACOLOGY, Aug. 2002, Peer-reviewed

  
• Brain extraction of 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]pyridinium ion (HPP+), a neurotoxic metabolite of haloperidol: Studies using [H-3]HPP+

  H Kawashima; Y Iida; Y Kitamura; Y Kiyono; Y Magata; H Saji

  JAPANESE JOURNAL OF PHARMACOLOGY, Aug. 2002, Peer-reviewed

  
• Age-related changes of myocardial norepinephrine transporter density in rats: implications for differential cardiac accumulation of MIBG in aging

  Y Kiyono; N Kanegawa; H Kawashima; Y Iida; T Kinoshita; N Tamaki; H Nishimura; M Ogawa; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Aug. 2002, Peer-reviewed

  
• Evaluation of radioiodinated 5-iodo-3-(2(S)-azetidinylmethoxy)pyridine as a ligand for SPECT investigations of brain nicotinic acetylcholine receptors

  H Saji; M Ogawa; M Ueda; Y Iida; Y Magata; A Tominaga; H Kawashima; Y Kitamura; M Nakagawa; Y Kiyono; T Mukai

  ANNALS OF NUCLEAR MEDICINE, May 2002, Peer-reviewed

  
• Control of radioactivity pharmacokinetics of Tc-99m-HYNIC-labeled polypeptides derivatized with ternary ligand complexes

  M Ono; Y Arano; T Mukai; T Saga; Y Fujioka; K Ogawa; H Kawashima; J Konishi; H Saji

  BIOCONJUGATE CHEMISTRY, May 2002, Peer-reviewed

  
• Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent Cu-diacetyl-bis(N-4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells

  A Obata; E Yoshimi; A Waki; JS Lewis; N Oyama; MJ Welch; H Saji; Y Yonekura; Y Fujibayashi

  ANNALS OF NUCLEAR MEDICINE, Dec. 2001, Peer-reviewed

  
• Effect of molecular charges on renal uptake of In-111-DTPA-conjugated peptides

  H Akizawa; Y Arano; M Mifune; A Iwado; Y Saito; T Mukai; T Uehara; M Ono; Y Fujioka; K Ogawa; Y Kiso; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Oct. 2001, Peer-reviewed

  
• Regional alterations of myocardial norepinephrine transporter density in streptozotocin-induced diabetic rats: implications for heterogeneous cardiac accumulation of MIBG in diabetes

  Y Kiyono; Y Iida; H Kawashima; N Tamaki; H Nishimura; H Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE, Jul. 2001, Peer-reviewed

  
• Significance of In-111-DTPA chelate in renal radioactivity levels of In-111-DTPA-conjugated peptides

  H Akizawa; Y Arano; M Mifune; A Iwado; Y Saito; T Uehara; M Ono; Y Fujioka; K Ogawa; Y Kiso; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, May 2001, Peer-reviewed

  
• Tc-99m-HYNIC-derivatized ternary ligand complexes for Tc-99m-labeled polypeptides with low in vivo protein binding

  M Ono; Y Arano; T Mukai; Y Fujioka; K Ogawa; T Uehara; T Saga; J Konishi; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Apr. 2001, Peer-reviewed

  
• Renal metabolism of 3 '-iodohippuryl N-epsilon-maleoyl-L-lysine (HML)-conjugated Fab fragments

  Y Fujioka; Y Arano; M Ono; T Uehara; K Ogawa; S Namba; T Saga; Y Nakamoto; T Mukai; J Konishi; H Saji

  BIOCONJUGATE CHEMISTRY, Mar. 2001, Peer-reviewed

  
• Performance assessment of O-18 water purifier

  H Kitano; Y Magata; A Tanaka; T Mukai; Y Kuge; K Nagatsu; J Konishi; H Saji

  ANNALS OF NUCLEAR MEDICINE, Feb. 2001, Peer-reviewed

  
• Plasma protein binding of Tc-99m-labeled hydrazino nicotinamide derivatized polypeptides and peptides

  M Ono; Y Arano; T Mukai; T Uehara; Y Fujioka; K Ogawa; S Namba; M Nakayama; T Saga; J Konishi; K Horiuchi; A Yokoyama; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Feb. 2001, Peer-reviewed

  
• Synthesis and evaluation of bisphosphonate derivative labeled with rhenium-186 using monoaminemonoamidedithiols as a chelating group.

  佐治 英郎

  J. Labelled Compd. Radiopharm.,44, 617-618, 2001, Peer-reviewed

  
• Single substitution of N-terminal amino acid in ¹¹¹In-DTPA-octreotide significantly affects renal accumulation.

  佐治 英郎

  J. Labelled Compd. Radiopharm.,44, 673-675, 2001, Peer-reviewed

  
• Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent Cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells.

  佐治 英郎

  Ann. Nucl. Med.,28(7), 761-768, 2001, Peer-reviewed

  
• Development of multi purpose synthetic system.

  佐治 英郎

  J. Labelled Compd. Radiopharm.,44, 1047-1049, 2001, Peer-reviewed

  
• Mechanisms of [2,3-butanedione bis(N-4-dimethylthiosemicarbazone)]zinc (Zn-ATSM(2))-induced protection of cultured hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity

  M Kubota; Y Iida; Y Magata; Y Kitamura; H Kawashima; H Saji

  JAPANESE JOURNAL OF PHARMACOLOGY, Nov. 2000, Peer-reviewed

  
• Protective effect of FK506 in the reperfusion model after short-term occlusion of middle cerebral artery in the rat: Assessment by autoradiography using [I-125]PK-11195

  N Miyazawa; H Saji; Y Takaishi; H Nukui

  NEUROLOGICAL RESEARCH, Sep. 2000, Peer-reviewed

  
• The development of Tc-99m-analog of Cu-DTS as an agent for imaging hypoxia

  K Horiuchi; T Tsukamoto; M Saito; M Nakayama; Y Fujibayashi; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, May 2000, Peer-reviewed

  
• Effect of chronic (-)-nicotine treatment on rat cerebral benzodiazepine receptors

  Y Magata; H Kitano; T Shiozaki; Y Iida; S Nishizawa; H Saji; J Konishi

  NUCLEAR MEDICINE AND BIOLOGY, Jan. 2000, Peer-reviewed

  
• PET and SPECT applications in medicine and pharmacology in Japan.

  佐治 英郎

  Ann. Nucl. Med. Sci,13/,225-232, 2000, Peer-reviewed

  
• Evaluation of radioiodinated medium chain fatty acids as new diagnostic agents for the determination of hepatic viability

  N Yamamura; Y Magata; J Konishi; H Saji

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE, Dec. 1999, Peer-reviewed

  
• The integrity of the disulfide bond in a cyclic somatostatin analog during Tc-99m complexation reactions

  T Uehara; Y Arano; M Ono; Y Fujioka; K Ogawa; S Namba; M Nakayama; M Koizumi; N Fujii; K Horiuchi; A Yokoyama; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Nov. 1999, Peer-reviewed

  
• Carrier effect on radiolabeling the polynuclear pentavalent rhenium-186 complex of dimercaptosuccinic acid at alkaline pH: Re-186(V)-DMS

  K Horiuchi; H Saji; A Yokoyama

  NUCLEAR MEDICINE AND BIOLOGY, Oct. 1999, Peer-reviewed

  
• Pharmacokinetic analysis of I-123-labeled medium chain fatty acid as a radiopharmaceutical for hepatic function based on beta-oxidation

  N Yamamura; Y Magata; F Yamashita; M Hashida; H Saji

  ANNALS OF NUCLEAR MEDICINE, Aug. 1999, Peer-reviewed

  
• Technetium-99m-labeled medium-chain fatty acid analogues metabolized by beta-oxidation: Radiopharmaceutical for assessing liver function

  N Yamamura; Y Magata; Y Arano; T Kawaguchi; K Ogawa; J Konishi; H Saji

  BIOCONJUGATE CHEMISTRY, May 1999, Peer-reviewed

  
• Intracellular metabolic fate of radioactivity after injection of technetium-99m-labeled hydrazino nicotinamide derivatized proteins

  M Ono; Y Arano; T Uehara; Y Fujioka; K Ogawa; S Namba; T Mukai; M Nakayama; H Saji

  BIOCONJUGATE CHEMISTRY, May 1999, Peer-reviewed

  
• Species difference in radioactivity elimination from liver parenchymal cells after injection of radiolabeled proteins

  T Mukai; Y Arano; K Nishida; H Sasaki; H Akizawa; K Ogawa; M Ono; H Saji; J Nakamura

  NUCLEAR MEDICINE AND BIOLOGY, Apr. 1999, Peer-reviewed

  
• A novel immunoscintigraphy technique using metabolizable linker with angiotensin II treatment

  Y Nakamoto; H Sakahara; T Saga; N Sato; S Zhao; Y Arano; Y Fujioka; H Saji; J Konishi

  BRITISH JOURNAL OF CANCER, Apr. 1999, Peer-reviewed

  
• Chemical design of radiolabeled antibody fragments for low renal radioactivity levels

  Y Arano; Y Fujioka; H Akizawa; M Ono; T Uehara; K Wakisaka; M Nakayama; H Sakahara; J Konishi; H Saji

  CANCER RESEARCH, Jan. 1999, Peer-reviewed

  
• In-vivo evaluation of indium-111-diethylenetriaminepentaacetic acid-labelling for determining the sites and rates of protein catabolism in mice

  T Mukai; Y Arano; K Nishida; H Sasaki; H Saji; J Nakamura

  JOURNAL OF PHARMACY AND PHARMACOLOGY, Jan. 1999, Peer-reviewed

  
• Development of fatty acid derivative labeled with Tc-99m using monoamine-monoamide dithiol as a chelating group: Recognized as a substrate for beta-oxidation

  Y. Magata; N. Yamamura; Y. Arano; H. Saji

  Journal of Labelled Compounds and Radiopharmaceuticals, 1999, Peer-reviewed

  
• Stability of disulfide bonds in synthetic somatostatin analogs during ^99mTc radiolabeling reactions

  T. Uehara; Y. Arano; M. Ono; Y. Fujioka; K. Ogawa; S. Namba; H. Hanaoka; M. Nakayama; N. Fujii; H. Saji

  Journal of Labelled Compounds and Radiopharmaceuticals, 1999, Peer-reviewed

  
• A new approach to retain target radioactivity levels of radioiodinated antibodies: A basic study for the chemical design

  K. Kawai; R. Nishii; T. Yamazaki; T. Uehara; Y. Arano; H. Saji; S. Tamura; A. Kubodera

  Journal of Labelled Compounds and Radiopharmaceuticals, 1999, Peer-reviewed

  
• Bis(hydroxamamide)-based bifunctional chelating agent for Tc-99m labeling of polypeptides

  LC Xu; M Nakayama; K Harada; A Kuniyasu; H Nakayama; S Tomiguchi; A Kojima; M Takahashi; M Ono; Y Arano; H Saji; ZS Yao; H Sakahara; J Konishi; Y Imagawa

  BIOCONJUGATE CHEMISTRY, Jan. 1999, Peer-reviewed

  
• Targeted delivery of radiolabeled imaging and therapeutic agents: Bifunctional radiopharmaceuticals

  H Saji

  CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 1999, Peer-reviewed

  
• Renal metabolism of In-111-DTPA-D-Phe(1)-octreotide in vivo

  H Akizawa; Y Arano; T Uezono; M Ono; Y Fujioka; T Uehara; A Yokoyama; K Akaji; Y Kiso; M Koizumi; H Saji

  BIOCONJUGATE CHEMISTRY, Nov. 1998, Peer-reviewed

  
• A radioiodinated biocytin derivative for in-vivo applications

  Y Nakamoto; H Sakahara; T Saga; Z Yao; M Zhang; N Sato; S Zhao; Y Arano; M Ono; H Saji; J Konishi

  NUCLEAR MEDICINE COMMUNICATIONS, Oct. 1998, Peer-reviewed

  
• pH sensitive properties of Tc(V)-DMS: Analytical and in vitro cellular studies

  K Horiuchi; H Saji; A Yokoyama

  NUCLEAR MEDICINE AND BIOLOGY, Oct. 1998, Peer-reviewed

  
• Tc(V)-DMS tumor localization mechanism: A pH-sensitive Tc(V)-DMS - Enhanced target/nontarget ratio by glucose-mediated acidosis

  K Horiuchi; H Saji; A Yokoyama

  NUCLEAR MEDICINE AND BIOLOGY, Aug. 1998, Peer-reviewed

  
• Assessment of the radiochemical design of antibodies with a metabolizable linkage for target-selective radioactivity delivery

  Y Arano; K Wakisaka; H Akizawa; M Ono; K Kawai; M Nakayama; H Sakahara; J Konishi; H Saji

  BIOCONJUGATE CHEMISTRY, Jul. 1998, Peer-reviewed

  
• Evaluation of [1-C-11]octanoate as a new radiopharmaceutical for assessing liver function using positron emission tomography

  N Yamamura; Y Magata; H Kitano; J Konishi; H Saji

  NUCLEAR MEDICINE AND BIOLOGY, Jul. 1998, Peer-reviewed

  
• Pharmacokinetic models to evaluate radiolabeling reagents for protein radiopharmaceuticals

  T Mukai; Y Arano; K Nishida; H Sasaki; J Nakamura; H Saji; A Yokoyama

  NUCLEAR MEDICINE AND BIOLOGY, Jan. 1998, Peer-reviewed

  
• Effect of ginseng pretreatment on cerebral glucose metabolism in ischaemic rats using animal positron emission tomography (PET) and [F-18]-FDG

  Choi, SR; Y Magata; H Saji; K Tajima; H Kitano; J Konishi; A Yokoyama

  PHYTOTHERAPY RESEARCH, Sep. 1997, Peer-reviewed

  
• A novel radioiodination reagent for protein radiopharmaceuticals with L-lysine as a plasma-stable metabolizable linkage to liberate m-iodohippuric acid after lysosomal proteolysis

  K Wakisaka; Y Arano; T Uezono; H Akizawa; M Ono; K Kawai; Y Ohomomo; M Nakayama; H Saji

  JOURNAL OF MEDICINAL CHEMISTRY, Aug. 1997, Peer-reviewed

  
• Conventional and high-yield synthesis of DTPA-conjugated peptides: Application of a monoreactive DTPA to DTPA-D-Phe(1)-octreotide synthesis

  Y Arano; H Akizawa; T Uezono; K Akaji; M Ono; S Funakoshi; M Koizumi; A Yokoyama; Y Kiso; H Saji

  BIOCONJUGATE CHEMISTRY, May 1997, Peer-reviewed

  
• Synthesis and characterization of radioiodinated (S)-5-iodonicotine: A new ligand for potential imaging of brain nicotinic cholinergic receptors by single photon emission computed tomography

  H Saji; A Watanabe; Y Magata; Y Ohmomo; Y Kiyono; Y Yamada; Y Iida; Y Yonekura; J Konishi; A Yokoyama

  CHEMICAL & PHARMACEUTICAL BULLETIN, Feb. 1997, Peer-reviewed

  
• Brain permeable zinc complex with neuroprotective action

  H Saji; T Kinoshita; M Kubota; K Kaneda; A Akaike; M Kikuchi; S Kashii; Y Honda; Y Iida; Y Magata; A Yokoyama

  STP PHARMA SCIENCES, Jan. 1997, Peer-reviewed

  
• Ginseng pretreatment protects against transient global cerebral ischemia in the rat: Measurement of local cerebral glucose utilization by [C-14]deoxyglucose autoradiography

  Choi, SR; H Saji; Y Iida; Y Magata; A Yokoyama

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Apr. 1996, Peer-reviewed

  
• Synthesis, in vitro binding profile and biodistribution of a (125)-labeled N-benzyl pyrrolidinyl benzamide derivative: A potential radioligand for mapping dopamine D-2 receptors

  H Saji; K Tanahashi; T Kinoshita; Y Iida; Y Magata; A Yokoyama

  NUCLEAR MEDICINE AND BIOLOGY, Feb. 1996, Peer-reviewed

  
• Recent advances in development of radiopharmaceuticals

  H. Saji

  Japanese Journal of Clinical Radiology, 1996, Peer-reviewed

  
• Nuclear imaging of drug action on the central nervous system

  H. Saji

  Folia Pharmacologica Japonica, 1996, Peer-reviewed

  
• APPLICATION OF [I-125] (S)-5-IODONICOTINE, A NEW RADIOIODINATED LIGAND, IN THE ASSAY OF NICOTINIC ACETYLCHOLINE-RECEPTOR BINDING IN THE BRAIN

  H SAJI; A WATANABE; Y KIYONO; Y MAGATA; Y IIDA; Y TAKAISHI; A YOKOYAMA

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, Nov. 1995, Peer-reviewed

  
• Initial clinical experiences with dopamine D2 receptor imaging by means of 2′-iodospiperone and single-photon emission computed tomography

  Yoshiharu Yonekura; Hideo Saji; Yasushi Iwasaki; Tatsuro Tsuchida; Hidenao Fukuyama; Akira Shimatsu; Yasuhiro Iida; Yasuhiro Magata; Junji Konishi; Akira Yokoyama; Hiroshi Shibasaki

  Annals of Nuclear Medicine, Sep. 1995, Peer-reviewed

  
• SPECT IMAGING OF DOPAMINE D2 RECEPTORS WITH 2'-IODOSPIPERONE

  Y IWASAKI; Y YONEKURA; H SAJI; S NISHIZAWA; H FUKUYAMA; Y IIDA; Y MAGATA; H SHIBASAKI; A YOKOYAMA; J KONISHI

  JOURNAL OF NUCLEAR MEDICINE, Jul. 1995, Peer-reviewed

  
• [I-125] IOMAZENIL BINDING IN THE BRAINS OF SPONTANEOUSLY EPILEPTIC RATS - AN EX-VIVO QUANTITATIVE AUTORADIOGRAPHIC STUDY

  T NAGATA; H SAJI; S NISHIZAWA; Y YONEKURA; YAMAMOTO, I; Y IIDA; Y MAGATA; J KONISHI; T SERIKAWA; A YOKOYAMA; R MORITA

  NUCLEAR MEDICINE AND BIOLOGY, May 1995, Peer-reviewed

  
• NONINVASIVE MEASUREMENT OF CEREBRAL BLOOD-FLOW AND GLUCOSE METABOLIC-RATE IN THE RAT WITH HIGH-RESOLUTION ANIMAL POSITRON EMISSION TOMOGRAPHY (PET) - A NOVEL IN-VIVO APPROACH FOR ASSESSING DRUG-ACTION IN THE BRAINS OF SMALL ANIMALS

  Y MAGATA; H SAJI; CHOI, SR; K TAJIMA; T TAKAGAKI; S SASAYAMA; Y YONEKURA; H KITANO; M WATANABE; H OKADA; E YOSHIKAWA; T YAMASHITA; A YOKOYAMA; J KONISHI

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, May 1995, Peer-reviewed

  
• Canine SPECT studies for cerebral amino acid transport by means of123I-3-iodo-α-methyl-L-tyrosine and preliminary kinetic analysis

  Keiichi Kawai; Yasuhisa Fujibayashi; Yoshiharu Yonekura; Kenichi Tanaka; Hideo Saji; Junji Konishi; Akiko Kubodera; Akira Yokoyama

  Annals of Nuclear Medicine, Mar. 1995, Peer-reviewed

  
• EVALUATION OF RADIOIODINATED IODOCLORGYLINE AS A SPECT RADIOPHARMACEUTICAL FOR MAO-A IN THE BRAIN

  M HIRATA; Y MAGATA; Y OHMOMO; H SAJI; K MURAKAMI; T TAKAGAKI; N YAMAMURA; C TANAKA; J KONISHI; A YOKOYAMA

  NUCLEAR MEDICINE AND BIOLOGY, Feb. 1995, Peer-reviewed

  
• 11C-labeled 2′-iododiazepam for PET studies of benzodiazepine receptors: Synthesis and comparison of biodistribution with its radioiodinated compound

  Yasuhiko Iida; Hideo Saji; Yasuhiro Magata; Junji Konishi; Iwao Nakatsuka; Akira Yoshitake; Akira Yokoyama

  Annals of Nuclear Medicine, Mar. 1994, Peer-reviewed

  
• RADIOIODINATED NORDIAZEPAM ANALOG FOR IN-VIVO ASSESSMENT OF BENZODIAZEPINE RECEPTORS BY SINGLE-PHOTON EMISSION TOMOGRAPHY

  H SAJI; Y IIDA; NAKATSUKA, I; M KATAOKA; T MIYAO; K ARIYOSHI; Y MAGATA; A YOSHITAKE; A YOKOYAMA

  NUCLEAR MEDICINE AND BIOLOGY, Jan. 1994, Peer-reviewed

  
• A new radioiodinated ligand for SPECT studies of peripheral benzodiazepine binding sites: 4\\'-Iodo-PK11195

  Y. Iida; H. Saji; I. Nakatsuka; M. Kataoka; Y. Magata; A. Yoshitake; A. Yokoyama

  Journal of Labelled Compounds and Radiopharmaceuticals, 1994, Peer-reviewed

  
• Radiofluorinated clorgyline derivative for mapping MAO-A activity in brain with PET

  M. Hirata; Y. Magata; Y. Ohmomo; H. Saji; C. Tanaka; A. Yokoyama

  Journal of Labelled Compounds and Radiopharmaceuticals, 1994, Peer-reviewed

  
• High reactivity of [11C]CH3I with thiol group in the synthesis of C-11 labeled radiopharmaceuticals

  Yasuhiro Magata; Hideo Saji; Taro Tokui; Yoshiro Ohmomo; Yoshihisa Yamada; Masahiko Hirata; Junji Konishi; Akira Yokoyama

  Annals of Nuclear Medicine, Sep. 1993, Peer-reviewed

  
• Myocardial accumulation of a dopamine D2 receptorbinding radioligand, 2′-iodospiperone

  Hideo Saji; Yoshiharu Yonekura; Kiyoko Tanahashi; Yasuhiko Iida; Yasushi Iwasaki; Yasuhiro Magata; Junji Konishi; Akira Yokoyama

  Annals of Nuclear Medicine, Sep. 1993, Peer-reviewed

  
• RADIOIODINATED 2'-IODODIAZEPAM - A POTENTIAL IMAGING AGENT FOR SPECT INVESTIGATIONS OF BENZODIAZEPINE RECEPTORS

  H SAJI; Y IIDA; NAKATSUKA, I; M KATAOKA; K ARIYOSHI; Y MAGATA; A YOSHITAKE; A YOKOYAMA

  JOURNAL OF NUCLEAR MEDICINE, Jun. 1993, Peer-reviewed

  
• AN APPROACH FOR ASSAYING BENZODIAZEPINE RECEPTOR-BINDING WITH RADIOIODINATED LIGAND - I-125 LABELED DIAZEPAM DERIVATIVE

  H SAJI; Y IIDA; K ARIYOSHI; NAKATSUKA, I; M KATAOKA; A YOSHITAKE; A YOKOYAMA

  BIOLOGICAL & PHARMACEUTICAL BULLETIN, May 1993, Peer-reviewed

  
• SYNTHESIS AND INVIVO BEHAVIOR OF A COPPER-64-LABELED DITHIOSEMICARBAZONE DERIVATIVE COUPLED TO A DIHYDROPYRIDINE CARRIER

  H SAJI; A SAIGA; Y IIDA; Y MAGATA; A YOKOYAMA

  JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Feb. 1993, Peer-reviewed

  
• SYNTHESIS OF RADIOIODINATED 2'-IODOBUTYROPHENONE DERIVATIVES

  NAKATSUKA, I; K SHIBA; H SAJI; A YOSHITAKE; A YOKOYAMA

  JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Feb. 1993, Peer-reviewed

  
• LOCAL CEREBRAL GLUCOSE-UTILIZATION IN THE INTERICTAL STATE OF THE SPONTANEOUSLY EPILEPTIC RAT (SER)

  H SAJI; Y IIDA; M TAKAHASHI; M SASA; T SERIKAWA; J YAMADA; A YOKOYAMA

  BRAIN RESEARCH, Jan. 1993, Peer-reviewed

  
• Studies on the effects of smoking on cerebral perfusion and metabolism: Basic studies with in vivo tracer methods

  J. Konishi; Y. Magata; Y. Yonekura; Y. Fujibayashi; H. Saji; Y. Yamada; A. Yokoyama

  Japanese Journal of Psychopharmacology, 1993, Peer-reviewed

  
• An artificial amino acid radiopharmaceutical for single photon emission computed tomographic study of pancreatic amino acid transports123I-3-iodo-alpha-methyl-L-tyrosine

  Keiichi Kawai; Yasuhisa Fujibayashi; Yoshiharu Yonekura; Junji Konishi; Hideo Saji; Akiko Kubodera; Akira Yokoyama

  Annals of Nuclear Medicine, Sep. 1992, Peer-reviewed

  
• Accumulation of radioactivity in the pancreas after intravenous administration of [¹³N]ammonia

  H. Saji; Y. Kuge; K. Yamamoto; Y. Magata; Y. Yonekura; J. Konishi; A. Yokoyama

  Nuclear Medicine and Biology, Jul. 1992, Peer-reviewed

  
• Preparation of ¹²³I-labeled 2′-iodospiperone and imaging of D₂ dopamine receptors in the human brain using SPECT

  H. Saji; Y. Iida; Y. Magata; Y. Yonekura; Y. Iwasaki; S. Sasayama; J. Konishi; I. Nakatsuka; K. Shiba; A. Yoshitake; A. Yokoyama

  International Journal of Radiation Applications and Instrumentation., Jul. 1992, Peer-reviewed

  
• A SEROLOGICALLY DEFINED HLA-A11 SPLIT ANTIGEN

  Y IWASAKI; K SHIODA; E MARUYA; H SAJI; TD LEE

  TISSUE ANTIGENS, Jul. 1992, Peer-reviewed

  
• SYNTHESIS AND BIOLOGICAL EVALUATION OF A N-13 LABELED OPIOID PEPTIDE

  H SAJI; D TSUTSUMI; Y KISO; S IIMUMA; T MIMOTO; K AKAJI; Y MAGATA; H NAKAMURA; A KITA; J KONISHI; A YOKOYAMA

  NUCLEAR MEDICINE AND BIOLOGY, May 1992, Peer-reviewed

  
• DEVELOPMENT OF A NOVEL RADIOIODINATED GLUCOSE DERIVATIVE WITH INTERACTION TO HEXOKINASE

  Y MAGATA; H SAJI; Y OHMOMO; C TANAKA; J KONISHI; A YOKOYAMA

  JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Apr. 1992, Peer-reviewed

  
• SYNTHESIS OF (S)-N-[METHYL-C-11]NICOTINE AND ITS REGIONAL DISTRIBUTION IN THE MOUSE-BRAIN - A POTENTIAL TRACER FOR VISUALIZATION OF BRAIN NICOTINIC RECEPTORS BY POSITRON EMISSION TOMOGRAPHY

  H SAJI; Y MAGATA; Y YAMADA; K TAJIMA; Y YONEKURA; J KONISHI; Y OHMOMO; A YOKOYAMA

  CHEMICAL & PHARMACEUTICAL BULLETIN, Mar. 1992, Peer-reviewed

  
• Preparation and biodistribution in mice of [11C]carfentanil: A radiopharmaceutical for studying brain μ-opioid receptors by positron emission tomography

  Hideo Saji; Daisuke Tsutsumi; Yasuhiro Magata; Yasuhiko Iida; Junji Konishi; Akira Yokoyama

  Annals of Nuclear Medicine, Mar. 1992, Peer-reviewed

  
• EVALUATION OF N-ALKYL DERIVATIVES OF RADIOIODINATED SPIPERONE AS RADIOLIGANDS FOR INVIVO DOPAMINE-D2 RECEPTOR STUDIES - EFFECTS OF LIPOPHILICITY AND RECEPTOR AFFINITY ON THE INVIVO BIODISTRIBUTION

  H SAJI; T TOKUI; NAKATSUKA, I; A SAIGA; Y MAGATA; K SHIBA; A YOSHITAKE; A YOKOYAMA

  CHEMICAL & PHARMACEUTICAL BULLETIN, Jan. 1992, Peer-reviewed

  
• INVESTIGATION OF RADIOPHARMACEUTICALS FOR PANCREATIC IMAGING - ACCUMULATION OF AMINES IN THE PANCREAS

  H SAJI; Y KUGE; Y MAGATA; Y FUJIBAYASHI; A YOKOYAMA

  CHEMICAL & PHARMACEUTICAL BULLETIN, Jan. 1992, Peer-reviewed

  
• Accumulation and metabolism of [125I] HIPDM in the rat pancreas

  Hideo Saji; Yuji Kuge; Daisuke Tsutsumi; Kazutaka Yamamoto; Junji Konishi; Akira Yokoyama

  Annals of Nuclear Medicine, Dec. 1991, Peer-reviewed

  
• A SYNTHETIC METHOD SUITABLE FOR THE RAPID PREPARATION OF N-13 LABELED DERMORPHIN ANALOG, H-TYR-D-MET(O)-PHE-GLY-NH2 (SD-62)

  Y KISO; S IINUMA; T MIMOTO; H SAJI; A YOKOYAMA; K AKAJI

  CHEMICAL & PHARMACEUTICAL BULLETIN, Oct. 1991, Peer-reviewed

  
• A STRATEGY FOR THE STUDY OF CEREBRAL AMINO-ACID-TRANSPORT USING IODINE-123-LABELED AMINO-ACID RADIOPHARMACEUTICAL - 3-IODO-ALPHA-METHYL-L-TYROSINE

  K KAWAI; Y FUJIBAYASHI; H SAJI; Y YONEKURA; J KONISHI; A KUBODERA; A YOKOYAMA

  JOURNAL OF NUCLEAR MEDICINE, May 1991, Peer-reviewed

  
• Synthesis and biological evaluation of esterified radioiodinated glucose derivative

  Y. Magata; M. Inagaki; Y. Ohmomo; Y. Yamada; H. Saji; A. Yokoyama

  Journal of Labelled Compounds and Radiopharmaceuticals, 1991, Peer-reviewed

  
• Current and future radiopharmaceuticals for brain functional studies with PET and SPECT

  H. Saji; A. Yokoyama

  Nippon rinsho. Japanese journal of clinical medicine, 1991, Peer-reviewed

  
• Opioid receptor

  H. Saji

  Nippon rinsho. Japanese journal of clinical medicine, 1991, Peer-reviewed

  
• HUMAN PANCREAS SCINTIGRAPHY USING IODINE-123-LABELED HIPDM AND SPECT

  K YAMAMOTO; T SHIBATA; H SAJI; S KUBO; E AOKI; T FUJITA; Y YONEKURA; J KONISHI; A YOKOYAMA

  JOURNAL OF NUCLEAR MEDICINE, Jun. 1990, Peer-reviewed

  
• LIGANDIN BINDING PHTHALEIN COMPLEXONE COMPLEX OF TECHNETIUM FOR HEPATIC-FUNCTION STUDIES

  K HORIUCHI; H SAJI; Y ARANO; A YOKOYAMA

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE, Mar. 1990, Peer-reviewed

  
• Monoiodo-d-tyrosine, an artificial amino acid radiopharmaceutical for selective measurement of membrane amino acid transport in the pancreas

  K. Kawai; Y. Fujibayashi; H. Saji; J. Konishi; A. Kubodera; A. Yokoyama

  International Journal of Radiation Applications and Instrumentation., 1990, Peer-reviewed

  
• Fatty acid metabolism using C-11 palmitate: (1) resting study

  N. Tamaki; Y. Yonekura; Y. Magata; H. Saji; Y. Fujibayashi; S. Sasayama; K. Yamashita; H. Ohtani; T. Fujita; T. Yamada; R. Nohara; H. Kambara; C. Kawai; J. Konishi

  Kakuigaku, 1990, Peer-reviewed

  
• QUANTITATIVE-ANALYSIS OF REGIONAL WALL MOTION BY GATED MYOCARDIAL POSITRON EMISSION TOMOGRAPHY - VALIDATION AND COMPARISON WITH LEFT VENTRICULOGRAPHY

  K YAMASHITA; N TAMAKI; Y YONEKURA; H OHTANI; H SAJI; T MUKAI; H KAMBARA; C KAWAI; T BAN; J KONISHI

  JOURNAL OF NUCLEAR MEDICINE, Nov. 1989, Peer-reviewed

  
• POSITRON EMISSION TOMOGRAPHY USING F-18 DEOXYGLUCOSE IN EVALUATION OF CORONARY-ARTERY BYPASS-GRAFTING

  N TAMAKI; Y YONEKURA; K YAMASHITA; H SAJI; Y MAGATA; M SENDA; Y KONISHI; K HIRATA; T BAN; J KONISHI

  AMERICAN JOURNAL OF CARDIOLOGY, Oct. 1989, Peer-reviewed

  
• VALUE OF REST-STRESS MYOCARDIAL POSITRON TOMOGRAPHY USING N-13 AMMONIA FOR THE PREOPERATIVE PREDICTION OF REVERSIBLE ASYNERGY

  N TAMAKI; Y YONEKURA; K YAMASHITA; M SENDA; H SAJI; Y KONISHI; K HIRATA; T BAN; J KONISHI

  JOURNAL OF NUCLEAR MEDICINE, Aug. 1989, Peer-reviewed

  
• REGIONAL DYNAMICS OF N-ISOPROPYL-(I-123)PARA-IODOAMPHETAMINE IN HUMAN-BRAIN

  S NISHIZAWA; S TANADA; Y YONEKURA; T FUJITA; T MUKAI; H SAJI; H FUKUYAMA; T MIYOSHI; K HARADA; M ISHIKAWA; H KIKUCHI; J KONISHI

  JOURNAL OF NUCLEAR MEDICINE, Feb. 1989, Peer-reviewed

  
• Assessment of myocardial viability by quantitative analysis of stress TI-SPECT - Comparison with FDG-PET

  H. Ohtani; N. Tamaki; K. Yamashita; Y. Yonekura; Y. Magata; H. Saji; I. H. Mohiuddin; R. Nohara; H. Kambara; C. Kawai; K. Hirata; T. Ban; J. Konishi

  Kakuigaku, 1989, Peer-reviewed

  
• Design, synthesis and ⁶⁴Cu labeling of fatty acid analogs containing dithiosemicarbazone chelate

  Y. Arano; Y. Magata; K. Horiuchi; K. Matsumoto; Y. Fujibayashi; Y. Ohmomo; C. Tanaka; H. Saji; A. Yokoyama

  International Journal of Radiation Applications and Instrumentation. Part, 1989, Peer-reviewed

  
• DYNAMIC POSITRON EMISSION TOMOGRAPHY WITH N-13 AMMONIA IN LIVER-TUMORS

  T SHIBATA; K YAMAMOTO; N HAYASHI; Y YONEKURA; T NAGARA; H SAJI; T MUKAI; J KONISHI

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE, Dec. 1988, Peer-reviewed

  
• A new subtraction method for obtaining myocardial perfusion images with oxygen-15 water and positron emission tomography

  Michio Senda; Sadahiko Nishizawa; Yoshiharu Yonekura; Nagara Tamaki; Hideo Saji; Takao Mukai; Junji Konishi

  Annals of Nuclear Medicine, Dec. 1988, Peer-reviewed

  
• RELATION OF LEFT-VENTRICULAR PERFUSION AND WALL MOTION WITH METABOLIC-ACTIVITY IN PERSISTENT DEFECTS ON TL-201 TOMOGRAPHY IN HEALED MYOCARDIAL-INFARCTION

  N TAMAKI; Y YONEKURA; K YAMASHITA; M SENDA; H SAJI; T HASHIMOTO; T FUDO; H KAMBARA; C KAWAI; T BAN; J KONISHI

  AMERICAN JOURNAL OF CARDIOLOGY, Aug. 1988, Peer-reviewed

  
• Measurement of arterial time-activity curve by monitoring continuously drawn arterial blood with an external detector: Errors and corrections

  Michio Senda; Sadahiko Nishizawa; Yoshiharu Yonekura; Takao Mukai; Hideo Saji; Junji Konishi; Kanji Torizuka

  Annals of Nuclear Medicine, Jun. 1988, Peer-reviewed

  
• Metabolic studies of p-iodophenylalanine in pancreas: A gateway to the development of radioiodinated amino acid for functional diagnosis

  K. Kawai; Y. Fujibayashi; H. Saji; J. Konishi; A. Yokoyama

  Kakuigaku, 1988, Peer-reviewed

  
• Detection of metabolic alterations in ischemic myocardium by F-18 fluorodeoxyglucose uptake with positron emission tomography

  Y. Yonekura; N. Tamaki; H. Kambara; M. Senda; H. Saji; T. Ban; C. Kawai; J. Konishi

  American Journal of Cardiac Imaging, 1988, Peer-reviewed

  
• Accumulation of fluorodeoxyglucose in ischemic myocardium: III. Assessment of the effects of coronary bypass surgery

  N. Tamaki; Y. Yonekura; K. Yamashita; M. Senda; H. Saji; K. Yamamoto; S. Nishizawa; K. Hirata; Y. Konishi; T. Ban; J. Konishi

  Kakuigaku, 1988, Peer-reviewed

  
• Value and limitation of stress thallium-201 single photon emission computed tomography: Comparison with nitrogen-13 ammonia positron tomography

  N. Tamaki; Y. Yonekura; M. Senda; K. Yamashita; H. Koide; H. Saji; T. Hashimoto; T. Fudo; H. Kambara; C. Kawai; J. Konishi

  Journal of Nuclear Medicine, 1988, Peer-reviewed

  
• Validity of positron emission tomography (PET) using 2-deoxy-2-[18F]fluoro-D-glucose (FDG) in patients with renal cell carcinoma (preliminary report)

  J. Kawamura; S. Hida; O. Yoshida; Y. Yonekura; M. Senda; K. Yamamoto; H. Saji; T. Fujita; J. Konishi

  Kakuigaku, 1988, Peer-reviewed

  
• RADIOIODINATED 2'-IODOSPIPERONE - A NEW RADIOLIGAND FOR INVIVO DOPAMINE RECEPTOR STUDY

  H SAJI; NAKATSUKA, I; K SHIBA; T TOKUI; K HORIUCHI; A YOSHITAKE; K TORIZUKA; A YOKOYAMA

  LIFE SCIENCES, Oct. 1987, Peer-reviewed

  
• INVITRO EVALUATION OF RADIOIODINATED BUTYROPHENONES AS RADIOTRACER FOR DOPAMINE RECEPTOR STUDY

  NAKATSUKA, I; H SAJI; K SHIBA; H SHIMIZU; M OKUNO; A YOSHITAKE; A YOKOYAMA

  LIFE SCIENCES, Oct. 1987, Peer-reviewed

  
• DETECTION OF CORONARY-ARTERY DISEASE WITH N-13 AMMONIA AND HIGH-RESOLUTION POSITRON-EMISSION COMPUTED-TOMOGRAPHY

  Y YONEKURA; N TAMAKI; M SENDA; R NOHARA; H KAMBARA; Y KONISHI; H KOIDE; SA KURESHI; H SAJI; T BAN; C KAWAI; K TORIZUKA

  AMERICAN HEART JOURNAL, Mar. 1987, Peer-reviewed

  
• Procurement of radioiodinated glucose derivative and its biological character

  Y. Magata; H. Saji; Y. Arano; K. Horiuchi; K. Torizuka; A. Yokoyama

  International Journal of Radiation Applications and Instrumentation., 1987, Peer-reviewed

  
• A case of angina after myocardial infarction with ST elevation on exercise associated with 18F-fluorodeoxy glucose uptake at the area of 13N-NH3 hypoperfusion

  R. Nohara; H. Kambara; T. Hashimoto; T. Fudo; C. Kawai; Y. Yonekura; M. Senda; H. Saji; K. Torizuka

  Respiration and Circulation, 1987, Peer-reviewed

  
• Technetium-99m-labeled monoclonal antibody with preserved immunoreactivity and high in vivo stability

  Y. Arano; A. Yokoyama; T. Furukawa; K. Horiuchi; T. Yahata; H. Saji; H. Sakahara; T. Nakashima; M. Koizumi; K. Endo

  Journal of Nuclear Medicine, 1987, Peer-reviewed

  
• Clinical usefulness of positron emission tomography in the evaluation of regional cerebral blood flow and cerebral oxygen metabolism under glycerol and carbon dioxide loadings

  S. Tanada; Y. Yonekura; M. Senda; H. Saji; T. Fujita; K. Torizuka; A. Kobayashi; W. Taki; M. Ishikawa; H. Handa

  Kakuigaku, 1987, Peer-reviewed

  
• INTERPOLATING SCAN AND OBLIQUE-ANGLE TOMOGRAMS IN MYOCARDIAL PET USING N-13 AMMONIA

  M SENDA; Y YONEKURA; N TAMAKI; H SAJI; H KOIDE; R NOHARA; H KAMBARA; Y KONISHI; K TORIZUKA

  JOURNAL OF NUCLEAR MEDICINE, Dec. 1986, Peer-reviewed

  
• NEW APPROACH FOR THE SEARCH OF EXPLOITABLE FUNCTION OF AMINO-ACID AS FOR PANCREATIC RADIOPHARMACEUTICAL

  Y FUJIBAYASHI; K KAWAI; H SAJI; K TORIZUKA; A YOKOYAMA

  JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Oct. 1986, Peer-reviewed

  
• INVIVO EVALUATION OF RADIOIODINATED SPIROPERIDOL DERIVATIVES AS RADIOPHARMACEUTICAL FOR DOPAMINE RECEPTOR STUDY

  H SAJI; T TOKUI; A SAIGA; Y KUGE; NAKATSUKA, I; M OKUNO; A YOSHITAKE; K TORIZUKA; A YOKOYAMA

  JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, Oct. 1986, Peer-reviewed

  
• Design of bifunctional radiopharmaceutical for the development of ^99mTc complexes for myocardial imaging agents

  T. Hosotani; A. Yokoyama; Y. Arano; K. Horiuchi; H. Saji; K. Torizuka

  International Journal of Radiation Applications and Instrumentation., 1986, Peer-reviewed

  
• Accumulation of fluorodeoxyglucose in ischemic myocardium. I. Comparison with myocardial perfusion at rest and during exercise

  Y. Yonekura; M. Senda; H. Koide; H. Saji; K. Yamamoto; S. Nishizawa; K. Torizuka; T. Fudo; T. Hashimoto; H. Kambara

  Kaku igaku. The Japanese journal of nuclear medicine, 1986, Peer-reviewed

  
• Significance of HLA analysis and penetrance of ASH in familial cardiomyopathy with coexisting hypertrophic and dilated-like types in two families

  C. Kishimoto; N. Tomioka; C. Kawai; S. Tamaki; K. Kadota; E. Maruya; H. Saji

  Respiration and Circulation, 1986, Peer-reviewed

  
• IN THE PROCUREMENT OF STABLE TC-99M LABELED PROTEIN USING BIFUNCTIONAL CHELATING AGENT

  Y ARANO; A YOKOYAMA; Y MAGATA; K HORIUCHI; H SAJI; K TORIZUKA

  APPLIED RADIATION AND ISOTOPES, 1986, Peer-reviewed

  
• IN THE PROCUREMENT OF A NEUTRAL AND COMPACT MONOMERIC COMPLEX OF DITHIOSEMICARBAZONE (DTS) DERIVATIVE - TC-99M-KTS

  T HOSOTANI; A YOKOYAMA; Y ARANO; K HORIUCHI; H WASAKI; H SAJI; K TORIZUKA

  INTERNATIONAL JOURNAL OF NUCLEAR MEDICINE & BIOLOGY, 1986, Peer-reviewed

  
• SYNTHESIS AND EVALUATION OF A NEW BIFUNCTIONAL CHELATING AGENT FOR TC-99M LABELING PROTEINS - PARA-CARBOXYETHYLPHENYLGLYOXAL-DI(N-METHYLTHIOSEMICARBAZONE)

  Y ARANO; A YOKOYAMA; Y MAGATA; H SAJI; K HORIUCHI; K TORIZUKA

  INTERNATIONAL JOURNAL OF NUCLEAR MEDICINE & BIOLOGY, 1986, Peer-reviewed

  
• A RADIOPHARMACEUTICAL FOR PANCREATIC EXOCRINE FUNCTIONAL DIAGNOSIS - ZN-62 EDDA METABOLISM IN PANCREAS

  Y FUJIBAYASHI; H SAJI; K KAWAI; Y UNUMA; S MIYATA; T OKUNO; R HOSOTANI; K INOUE; H ADACHI; K HORIUCHI; K TORIZUKA; A YOKOYAMA

  INTERNATIONAL JOURNAL OF NUCLEAR MEDICINE & BIOLOGY, 1986, Peer-reviewed

  
• ⁶²Zn-EDDA: A radiopharmaceutical for pancreatic functional diagnosis

  Y. Fujibayashi; H. Saji; I. Yomoda

  International Journal of Nuclear Medicine and Biology, 1986, Peer-reviewed

  
• A new approach toward a pancreas-seeking zinc radiopharmaceutical - I. Accumulation of ⁶⁵Zn-amino acid and aminopolycarboxylic acid complexes in pancreatic tissue slices

  Y. Fujibayashi; H. Saji; I. Yomoda; K.H. Suzuki; K. Torizuka; A. Yokoyama

  European Journal of Nuclear Medicine, 1986, Peer-reviewed

  
• A new approach toward a pancreas-seeking zinc radiopharmaceutical - II. ⁶²Zn-EDDA (ethylenediamine-N,N′-diacetic acid) for pancreas PCT imaging

  Y. Fuijbayashi; H. Saji; I. Yomoda; K.H. Suzuki; K. Torizuka; A. Yokoyama

  European Journal of Nuclear Medicine, 1986, Peer-reviewed

  
• IMAGING OF THE HEPATOCELLULAR-CARCINOMA USING DYNAMIC POSITRON EMISSION TOMOGRAPHY WITH N-13 AMMONIA

  N HAYASHI; N TAMAKI; Y YONEKURA; M SENDA; H SAJI; K YAMAMOTO; J KONISHI; K TORIZUKA

  JOURNAL OF NUCLEAR MEDICINE, 1985, Peer-reviewed

  
• Iron(III)-nitrilotriacetate: An agent for reducing the time interval of tumor imaging with gallium citrate

  H. Saji; N. Hata; K. Horiuchi; A. Yokoyama; K. Yamamoto; K. Torizuka

  International Journal of Nuclear Medicine and Biology, 1985, Peer-reviewed

  
• Myocardial positron computed tomography using N-13 ammonia for evaluating coronary artery disease: Comparison with thallium-201 emission computed tomography

  N. Tamaki; Y. Yonekura; S. Kodama; M. Senda; H. Saji; K. Torizuka; H. Kambara; C. Kawai; Y. Konishi; T. Ban

  Journal of Cardiography, 1985, Peer-reviewed

  
• The design of a pentavalent ^99mTc- dimercaptosuccinate complex as a tumor imaging agent

  A. Yokoyama; N. Hata; K. Horiuchi; H. Masuda; H. Saji; H. Ohta; K. Yamamoto; K. Endo; K. Torizuka

  International Journal of Nuclear Medicine and Biology, 1985, Peer-reviewed

  
• NONINVASIVE EVALUATION OF REGIONAL MYOCARDIAL PERFUSION WITH POSITRON EMISSION COMPUTED-TOMOGRAPHY

  K TORIZUKA; Y YONEKURA; N TAMAKI; M SENDA; H SAJI

  JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, 1985, Peer-reviewed

  
• DYNAMIC POSITRON COMPUTED-TOMOGRAPHY OF THE HEART WITH A HIGH-SENSITIVITY POSITRON CAMERA AND N-13 AMMONIA

  N TAMAKI; M SENDA; Y YONEKURA; H SAJI; S KODAMA; Y KONISHI; T BAN; H KAMBARA; C KAWAI; K TORIZUKA

  JOURNAL OF NUCLEAR MEDICINE, 1985, Peer-reviewed

  
• N-13 ammonia myocardial positron computed tomography. (3) Evaluation of coronary artery disease by stress imaging

  N. Tamaki; Y. Yonekura; M. Senda; S. Kodama; H. Saji; S. Tanada; K. Murata; Y. Konishi; T. Ban; H. Kambara

  Kakuigaku, 1985, Peer-reviewed

  
• In vivo kinetics and thrombus accumulation of ⁶⁷ga-labeled urokinase

  Y. Ohmomo; A. Yokoyama; Y. Yamauchi; K. Horiuchi; H. Saji; C. Tanaka; K. Torizuka

  International Journal of Nuclear Medicine and Biology, 1985, Peer-reviewed

  
• MYOCARDIAL POSITRON COMPUTED-TOMOGRAPHY WITH N-13-AMMONIA AT REST AND DURING EXERCISE

  N TAMAKI; Y YONEKURA; M SENDA; SA KURESHI; H SAJI; S KODAMA; Y KONISHI; T BAN; H KAMBARA; C KAWAI; K TORIZUKA

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1985, Peer-reviewed

  
• PERFORMANCE-CHARACTERISTICS OF POSITOLOGICA-III - A WHOLE-BODY POSITRON EMISSION TOMOGRAPH

  M SENDA; N TAMAKI; Y YONEKURA; S TANADA; K MURATA; N HAYASHI; T FUJITA; H SAJI; J KONISHI; K TORIZUKA; K ISHIMATSU; K TAKAMI; E TANAKA

  JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1985, Peer-reviewed

  
• [I125] RADIOIODINATED METARAMINOL - A NEW PLATELET-SPECIFIC LABELING AGENT

  Y OHMOMO; A YOKOYAMA; K KAWAI; Y ARANO; K HORIUCHI; C TANAKA; H SAJI; K TORIZUKA

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1985, Peer-reviewed

  
• Application of data processing. d. Positron CT

  K. Torizuka; Y. Yonekura; N. Tamaki; H. Saji

  Nippon rinsho. Japanese journal of clinical medicine, 1984, Peer-reviewed

  
• Development of automatic synthesis system for cyclotron - Produced radiopharmaceuticals 15O-water and 11C-cyanide.:—Produced radiopharmaceuticals ¹⁵O-water and ¹¹C-cyanide—

  NISHIHARA Yoshiaki; TANAKA Akira; ENOKI Kazuharu; SAJI Hideo; TORIZUKA Kanji

  RADIOISOTOPES, 1984, Peer-reviewed

  
• Procurement and biological significance of pure 11C-glucose.

  H. Saji; A. Tanaka; Y. Magata; K. Enoki; T. Tokui; Y. Nishihara; M. Senda; Y. Yonekura; A. Yokoyama; K. Torizuka

  Radioisotopes, 1984, Peer-reviewed

  
• Constant infusion system of 15O labeled-water

  H. Saji; K. Enoki; T. Tokui; Y. Yonekura; Y. Nishihara; A. Yokoyama; K. Torizuka

  Radioisotopes, 1984, Peer-reviewed

  
• Regional pulmonary function assessed by C15O2 and 11CO inhalation

  K. Murata; G. Todo; M. Senda; N. Tamaki; Y. Yonekura; H. Itoh; T. Fujita; T. Mukai; K. Minato; H. Saji

  Kakuigaku, 1984, Peer-reviewed

  
• CARRIER-ADDED AND NO-CARRIER-ADDED SYNTHESES OF [F-18] SPIROPERIDOL AND [F-18] HALOPERIDOL

  MR KILBOURN; MJ WELCH; CS DENCE; TJ TEWSON; H SAJI; M MAEDA

  INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES, 1984, Peer-reviewed

  
• Positron emission CT images and metabolic information

  K. Torizuka; R. Morita; Y. Yonekura; H. Saji; T. Fujita; S. Tanada; T. Higa; N. Tamaki; H. Itoh; G. Todo

  Nippon rinsho. Japanese journal of clinical medicine, 1983, Peer-reviewed

  
• DEFEROXAMINE, A PROMISING BIFUNCTIONAL CHELATING AGENT FOR LABELING PROTEINS WITH GALLIUM - GA-67 DF-HSA - CONCISE COMMUNICATION

  A YOKOYAMA; Y OHMOMO; K HORIUCHI; H SAJI; H TANAKA; K YAMAMOTO; Y ISHII; K TORIZUKA

  JOURNAL OF NUCLEAR MEDICINE, 1982, Peer-reviewed

  
• TIN-ADSORBED RESIN FOR THE PREPARATION OF TC-99M RADIOPHARMACEUTICAL - STABLE COMPLEX OF TC-99M BLEOMYCIN

  K HORIUCHI; A YOKOYAMA; Y FUJIBAYASHI; H TANAKA; T ODORI; H SAJI; R MORITA; K TORIZUKA

  INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES, 1981, Peer-reviewed

  
• TECHNETIUM COORDINATION STATE AS A FACTOR OF STABILITY IN TC-99M-LABELED COMPLEXES USED IN HEPATOBILIARY SYSTEM - COMPARATIVE STUDIES ON TC-99M-LABELED COMPLEXES OF PYRIDOXAL WITH GLUTAMATE (TC-PG) AND ISOLEUCINE (TC-PI)

  K HORIUCHI; A YOKOYAMA; H TANAKA; H SAJI; T ODORI; R MORITA; K TORIZUKA

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1981, Peer-reviewed

  
• ANALYSIS OF TC-99M-PYRIDOXYLIDENE-GLUTAMATE COMPLEX-FORMATION AND ITS PREPARATION WITH TIN-ADSORBED-RESIN - SN-RESIN KIT METHOD

  K HORIUCHI; A YOKOYAMA; H TANAKA; H SAJI; T ODORI; R MORITA; K TORIZUKA

  EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1981, Peer-reviewed

  
• EFFECT OF THE NATURE OF TECHNETIUM COORDINATION COMPLEX ON CELL-MEMBRANE PERMEABILITY - MONONUCLEAR COMPLEX OF TC-99M PENICILLAMINE ETHYL-ESTER

  K HORIUCHI; A YOKOYAMA; K TSUIKI; H TANAKA; H SAJI

  INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES, 1981, Peer-reviewed

  
• Basic and clinical studies on ^99mTc-N-(2,6-diethyl phenyl carbamoyl methyl) iminodiacetic acid ( ^99mTc-diethyl IDA) as a cholescintigraphic agent

  T. Odori; K. Yamamoto; H. Saji; Y. Yonekura; R. Morita; K. Torizuka; T. Fujita; K. Horiuchi; J. Misaki; N. Hata; A. Yokoyama; H. Muranaka

  Kakuigaku, 1980, Peer-reviewed

  
• Basic and clinical studies on Tc-99m-millimicrosphered albumin as a liver imaging agent (author\\'s transl)

  K. Yamamoto; H. Saji; Y. Ishii; K. Torizuka; Y. Fujibayashi; M. Miwa; A. Yokoyama

  Kakuigaku, 1980, Peer-reviewed

  
• Accumulation of Tc-99m into tumor by polynuclear complexes. II. Effect of Fe-NTA on tumor to blood ratios of Ga-67-citrate and Tc-99m-DMSA

  H. Saji; R. Morita; K. Torizuka

  Kakuigaku, 1980, Peer-reviewed

  
• Enhancement of 67Ga tumor-to-blood ratios by chelating agent (author\\'s transl)

  H. Saji; A. Yokoyama; N. Hata; A. Misaki; H. Tanaka; R. Morita; M. Fukunaga; K. Torizuka

  Radioisotopes, 1980, Peer-reviewed

  
• Clinical evaluation of (99m)Tc-pyridoxylidene glutamate as a cholescintigraphic agent labeled by a simplified method

  T. Odori; R. Morita; H. Saji

  Kakuigaku, 1979, Peer-reviewed

  
• 99mTc-2-mercaptopropionylglycine: different biliary excretion behavior in different animal species (author\\'s transl)

  H. Saji; A. Yokoyama; H. Tanaka; T. Odori; R. Morita; K. Torizuka

  Radioisotopes, 1979, Peer-reviewed

  
• An evaluation of a new bifunctional hepatobilliary scanning agent 99m-Tc-PC (PC: 3,3\\'-bis(n,n-di(carboxymethyl)-aminomethyl)-o-cresolphthalein

  H. Saji; T. Odori; R. Noriat

  Kakuigaku, 1979, Peer-reviewed

  
• Phthalein and fluorescein derivatives with an effective 99m-technetium labeled state for a hepatobiliary transport: 99m-Tc-PC, a new hepatobiliary radiopharmaceutical

  H. Saji; A. Yokoyama; Y. Arano

  Journal of Labelled Compounds and Radiopharmaceuticals, 1979, Peer-reviewed

  
• Basic and clinical studies on ^99mTc-pyridoxylidene glutamate and ^99mTc-pyridoxydeneisoleucine

  T. Odori; H. Saji; T. Fujita

  Kakuigaku, 1979, Peer-reviewed

  
• A remote-controlled synthesis of ¹¹C-iodomethane for the practical preparation of ¹¹C-labeled radiopharmaceuticals

  Ren Iwata; Tatsuo Ido; Hideo Saji; Kazutoshi Suzuki; Kikuo Yoshikawa; Kazuhiko Tamate; Yosihiko Kasida

  The International Journal Of Applied Radiation And Isotopes, 1979, Peer-reviewed

  
• Studies on the evaluation of the clinical usefulness of (99m)Tc-(Sn)-pyridoxylidene isoleucine as a cholescintigraphic agent

  T. Odori; R. Morita; H. Saji; T. Fujita; K. Torizuka; K. Horiuchi; A. Yokoyama; H. Matsuyama; H. Muranaka

  Kakuigaku, 1979, Peer-reviewed

  
• Caffeine-11C, ephedrine-11C and methylephedrine-11C: Synthesis and distribution in mice (author\\'s transl)

  H. Saji; T. Ido; R. Iwata; K. Suzuki; K. Tamate; K. Yoshikawa; Y. Kasida

  Radioisotopes, 1978, Peer-reviewed

  
• ⁹⁹Tc^m chemical state in ⁹⁹Tc^m labeled radio-pharmaceuticals-I. Preparation and biological behavior of ⁹⁹Tc^m-penicillamine complex with a low hydrolyzed ⁹⁹Tc^m state

  A. Yokoyama; H. Saji; K. Horiuchi; H. Tanaka; T. Odori; R. Morita; T. Mori; K. Torizuka

  International Journal of Nuclear Medicine and Biology, 1978, Peer-reviewed

  
• The preparation of ¹¹C-methyl iodide and its use in the synthesis of ¹¹C-caffeine

  H. Saji; T. Ido; R. Iwata

  Kakuigaku, 1978, Peer-reviewed

  
• An evaluation of (99m)Tc-labeled iminodiacetic acid derivatives of phthaleins and fluoresceins as hepatobiliary agents

  H. Saji; A. Yokoyama; Y. Arano

  Kakuigaku, 1978, Peer-reviewed

  
• An evaluation of (99m)Tc-HIDA complex as an cholescintigraphic agent

  A. Yokoyama; H. Saji; Y. Arano

  Kakuigaku, 1978, Peer-reviewed

  
• Fundamental and clinical investigation on the bone scintigraphy using ^99mTc-methylenediphosphonate

  S. Dokoh; R. Morita; I. Yamamoto; M. Fukunaga; T. Fujita; H. Saji; K. Torizuka

  Kakuigaku, 1978, Peer-reviewed

  
• Chemical character effect of 99m Tc penicillamine complexes on the in vivo behavior

  A. Yokoyama; H. Saji; K. Horiuchi; Y. Terauchi

  Journal of Labelled Compounds and Radiopharmaceuticals, 1977, Peer-reviewed

  
• Evaluation of 99mTc-HIDA complex as a cholescintigraphic agent (author\\'s transl)

  H. Saji; A. Yokoyama; Y. Arano; H. Tanaka; T. Odori; R. Morita; K. Torizuka

  Radioisotopes, 1977, Peer-reviewed

  
• Development of a new cholescintigraphic agent

  A. Yokoyama; H. Saji; Y. Terauchi

  Kakuigaku, 1977, Peer-reviewed

  
• Preparation of a chemically characterized ⁹⁹Tc(m) penicillamine complex

  A. Yokoyama; H. Saji; H. Tanaka; T. Odori; R. Morita

  Journal of Nuclear Medicine, 1976, Peer-reviewed

  
• Tc ⁹⁹(m) penicillamine labeling compounds with different biological behavior and labeling conditions required for their formations

  A. Yokoyama; H. Saji; H. Tanaka

  Kakuigaku, 1976, Peer-reviewed

  
• On the different biological behavior of Tc 99m penicillamine compounds in different animals (mouse, rat and rabbit)

  A. Yokoyama; H. Saji; Y. Terauchi

  Kakuigaku, 1976, Peer-reviewed

  

Misc.

• Imaging Study of a Phantom and Small Animal with a Two-Head Electron-Tracking Compton Gamma-Ray Camera

  Shigeto Kabuki; Hiroyuki Kimura; Hiroo Amano; Yuji Nakamoto; Hidetoshi Kubo; Kentaro Miuchi; Shunsuke Kurosawa; Michiaki Takahashi; Hidekazu Kawashima; Masashi Ueda; Tomohisa Okada; Koichi Ogawa; Kaori Togashi; Hideo Saji; Toru Tanimori

  2010 IEEE NUCLEAR SCIENCE SYMPOSIUM CONFERENCE RECORD (NSS/MIC), 2010, Peer-reviewed

  
• Imaging reagents study for nuclear medicine using an electron-tracking compton gamma-ray camera

  S. Kabuki; H. Kimura; H. Amano; Y. Nakamoto; H. Kubo; K. Miuchi; S. Kurosawa; M. Takahashi; H. Kawashima; M. Ueda; T. Okada; K. Ogawa; K. Togashi; H. Saji; T. Tanimori

  IEEE Nuclear Science Symposium Conference Record, 2009, Peer-reviewed

  
• 立体構造制 御に基づくon/off スイッチング機構を導入した新規機能性MRI プローブの開発

  正木悠紀子; 天満敬; 佐野紘平; 木村寛之; 東高志; 中井隆介; 久下裕司; 小野正博; 佐治英郎

  第８回放射性医薬品・画像 診断薬研究会（2008.12.6．京都）, 2008, Peer-reviewed

  
• Simultaneous imaging of multi nuclides using the electron tracking compton gamma-ray.camera based on small animal and phantom experiments

  S. Kabuki; H. Kubo; K. Miuchi; S. Kurosawa; H. Kimura; R. Kohara; O. Miyazaki; T. Nakazawa; T. Shirahata; E. Yamamoto; A. Kubo; E. Kunieda; T. Nakahara; H. Amano; H. Kawashima; M. Ueda; T. Okada; Y. Nakamoto; K. Ogawa; K. Togashi; H. Saji; T. Tanimori; K. Hattori; T. Nagayoshi; H. Nishimura; H. Sekiya; A. Takada; K. Ueno

  IEEE Nuclear Science Symposium Conference Record, 2008, Peer-reviewed

  
• Diagnostic approach of using an electron tracking Compton gamma-ray camera based on small animal and phantom experiments

  S. Kabuki; K. Hattori; H. Kawashima; H. Kimura; R. Kohara; A. Kubo; H. Kubo; S. Kurosawa; E. Kunieda; K. Miuchi; O. Miyazaki; T. Nagayoshi; T. Nakahara; Y. Nakamoto; T. Nakazawa; H. Nishimura; K. Ogawa; T. Okada; Y. Okada; R. Orito; H. Saji; H. Sekiya; T. Shirahata; A. Takada; T. Tanimori; K. Togashi; M. Ueda; K. Ueno; E. Yamamoto

  IEEE Nuclear Science Symposium Conference Record, 2007, Peer-reviewed

  
• Development of a electron tracking compton gamma-ray camera using a gas micro-tracking device for nuclear medicine

  S. Kabuki; K. Hattori; H. Kawashima; H. Kimura; R. Kohara; A. Kubo; H. Kubo; S. Kurosawa; E. Kunieda; O. Miyazaki; T. Nagayoshi; T. Nakahara; T. Nakazawa; H. Nishimura; K. Ogawa; Y. Okada; R. Orito; H. Saji; H. Sekiya; T. Shirahata; A. Takada; T. Tanimori; M. Ueda; K. Ueno; E. Yamamoto; K. Miuchi

  IEEE Nuclear Science Symposium Conference Record, 2007, Peer-reviewed

  

Books and Other Publications

• 図解放射性同位元素等取扱者必携

  佐治英郎; 倉橋和義; 戸崎充男; 角山雄一; 大澤大輔; 高屋成利; 宮武秀男; 石塚史彦, Joint work

  オーム社, 2007, Not refereed

  
• 生命科学のための無機化学・錯体化学

  佐治 英郎

  広川書店, 2005, Not refereed

  Find Kyoto University's collection of books :

  
• New 放射化学・放射薬品学

  佐治 英郎

  廣川書店,, 2004, Not refereed

  
• 新放射化学・放射性医薬品学

  佐治 英郎

  南江堂, 2003, Not refereed

  Find Kyoto University's collection of books :

  

Industrial Property Rights

• 特許5714016, スイッチング型蛍光ナノ粒子プローブ及びそれを用いた蛍光分子イメージング法

  佐治 英郎

  
• 特許5700835, 膵島イメージング用分子プローブ及びその使用

  佐治 英郎

  
• 特許5685401, 膵島イメージング用分子プローブ及びその前駆体、並びに、それらの使用

  佐治 英郎

  
• 特許5669725, 膵島イメージング用分子プローブ及びその使用

  佐治 英郎

  
• 特許5291791, [18F]SFBの合成方法

  佐治 英郎

  
• 特許5273571, 膵島イメージング用分子プローブ前駆体およびその使用

  佐治 英郎

  
• 特許5073871, タウタンパク質親和性化合物およびタウオパチー診断剤

  佐治 英郎

  

Works

• 悪性腫瘍特異的に発現する酵素を標的とした腫瘍イメージング用放射性医薬品の開発

  From 2000

  
• Active site-directed Rediopharmaceuticals : Targetting Over-expression of Malignant Fumor Specific Engymes

  From 2000

  
• 脳疾患心疾患およびガスの核医学診断に有用な放射性薬剤の開発研究

  From 1997

  
• レニウム-186,188標識化合物の新規開発

  From 1997

  
• Research on Development of New Radiopharmaceuticals for Brain, Heart and Tumor Diagnosis

  From 1997

  
• Joint Research on Development of a Novel Reniun-186,188 Labeled Cmmyound

  From 1997

  

Awards

• 1988

  日本核医学会, 日本核医学会賞
• 1994

  The Society of Nuclear Medicine, 米国核医学会機関誌 Journal of Nuclear Medicine 最優秀論文賞(Award of Most Significant Manuscript of 1993, Journal of Nuclear Medicine)
• 1994

  日本核医学会会長賞
• 2010

  先端医療技術研究所, 分子イメージング賞

External funds: Kakenhi

• Development of PET probes targeting pancreatic b-cells for early diagnosis and preemptive medicine of diabetes.

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Hideo Saji

  From 01 Apr. 2016, To 31 Mar. 2018, Project Closed

  PET;膵β細胞;糖尿病

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K15106/
• Development of a cancer-targeted diagnosis-therapy workflow system utilizing photoacoustic effect with near-infrared light

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Hideo Saji

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  分子イメージング;光音響法;近赤外光;光線照射療法;イメージング;がん治療

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H04637/
• Development of a novel Cherenkov imaging method for evaluating the effect of internal radiation therapy

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Saji Hideo

  From 01 Apr. 2014, To 31 Mar. 2016, Project Closed

  イメージング;チェレンコフ光;内用放射線治療

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26670011/
• GLP-1受容体を標的とする抗体イメージングによる膵β細胞療法の開発

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  豊田 健太郎

  From 01 Apr. 2013, To 31 Mar. 2015, Discontinued

  可視化;糖尿病

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25461878/
• Development of individualized radiotherapy with biological-image guidance and four-dimensional irradiation

  Grant-in-Aid for Scientific Research (A)

  Kyoto University

  Masahiro HIRAOKA

  From 01 Apr. 2013, To 31 Mar. 2018, Project Closed

  低酸素イメージング;４次元ＰＥＴ;４次元線量計算;動体追尾ＩＭＲＴ;四次元放射線治療;低酸素;腫瘍動態評価;動体追尾照射;医学物理学;4次元放射線治療;４次元放射線治療;四次元機能画像;低酸素画像;追尾照射;強度変調放射線治療

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25253078/
• Development of nuclear medical imaging probes targeting GSK-3beta for early diagnosis of tauopathy

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Hideo SAJI

  From 01 Apr. 2012, To 31 Mar. 2014, Project Closed

  タウオパチー;GSK-3β;認知症;イメージング;診断

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24659564/
• Development of small molecular radiolabeled probes for nuclear medical imaging of unstable plaques

  Grant-in-Aid for Scientific Research (C)

  National Cardiovascular Center Research Institute;Kyoto University

  TAKASHI TEMMA

  From 01 Apr. 2012, To 31 Mar. 2015, Project Closed

  放射性医薬品;動脈硬化イメージング;不安定プラーク

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24591813/
• Development of molecular imaging probes for measurement of mass in pancreatic islets.

  Grant-in-Aid for Scientific Research (A)

  Kyoto University

  Hideo SAJI

  From 01 Apr. 2010, To 31 Mar. 2013, Project Closed

  膵島β細胞;分子イメージング;糖尿病;早期診断

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22249046/
• Development of in vivo imaging probes for measurement of cell mass in pancreatic islets.

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Hideo SAJI

  From 01 Apr. 2009, To 31 Mar. 2012, Project Closed

  糖尿病;早期診断;分子イメージング;画像診断

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21659289/
• 不安定動脈硬化プラークの描出を目的とするSPECT分子イメージングプローブの開発

  Grant-in-Aid for Exploratory Research

  Kyoto University

  佐治 英郎

  From 01 Apr. 2007, To 31 Mar. 2009, Project Closed

  循環器・高血圧;放射線;動脈硬化;分子イメージング

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19659311/
• 脳機能再生機構の解析と分子イメージング~臨床画像診断の実現を目指して~

  Grant-in-Aid for Exploratory Research

  Hokkaido University

  久下 裕司

  From 01 Apr. 2007, To 31 Mar. 2009, Project Closed

  脳神経疾患;リハビリテーション;マイクロアレイ;移植・再生医療;放射線

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19659310/
• Development of probes for the systematic analysis of Alzheimer's disease : establishment of a new diagnostic imaging.

  Grant-in-Aid for Scientific Research (A)

  Kyoto University

  Hideo SAJI

  From 01 Apr. 2007, To 31 Mar. 2010, Project Closed

  アルツハイマー病;分子イメージング;放射線画像診断;トランスレーショナルリサーチ;痴呆;放射線;画像診断

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19209041/
• 酸素応答分解型タンパクを用いる低酸素領域のインビボ放射性イメージング法の開発

  Grant-in-Aid for Exploratory Research

  Kyoto University

  佐治 英郎

  From 01 Apr. 2005, To 31 Mar. 2007, Project Closed

  低酸素領域;腫瘍;分子イメージング;低酸素誘導因子;ビオチン誘導体;放射性医薬品

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17659010/
• トランスレーショナルPET研究の有用性の確立と安全性基準

  Grant-in-Aid for Scientific Research (C)

  Tohoku University

  谷内 一彦

  From 01 Apr. 2005, To 31 Mar. 2006, Project Closed

  PET;分子イメージング;安全性基準;探索的臨床試験;マイクロドーズ概念;産学連携;臨床研究の利益相反;アミロイドAβ蛋白

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17639014/
• Quantitative Analysis of Nicotinic Acetylcholine Receptors in Human Brain ; Effects of Aging and Smoking Cessation

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Koichi ISHIZU

  From 01 Apr. 2005, To 31 Mar. 2007, Project Closed

  5IA;ニコチン;SPECT;喫煙;受容体;ニコチン受容体;nAChR;定量;禁煙, 5IA;nicotine;SPECT;smoking;neuroreceptor

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17591263/
• Molecular imaging and strategies for cancer treatment: A Study to achieve noninvasive in vivo pathological evaluation by molecular imaging

  Grant-in-Aid for Scientific Research (B)

  Hokkaido University;Kyoto University

  Yuji KUGE

  From 01 Apr. 2005, To 31 Mar. 2008, Project Closed

  放射線;癌;分子イメージング;治療, Radioisotope;Cancer;Molecular imaging;Therapy

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17390332/
• 動脈硬化病態の解析と分子イメージング:プロスタグランジン合成酵素を標的として

  Grant-in-Aid for Exploratory Research

  Kyoto University

  久下 裕司

  From 01 Apr. 2004, To 31 Mar. 2006, Project Closed

  動脈硬化;分子イメージング;プロスタグランジン;シクロオキシゲナーゼ(COX-2);シングルフォトンCT(SPECT);ポジトロンCT(PET);シンロオキシゲナーゼ(COX-2)

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16659315/
• In vivo imaging of nicotinic acetylcholine recptors in patients with Parkinson's disease

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  Kazuo HASHIKAWA

  From 01 Apr. 2004, To 31 Mar. 2006, Project Closed

  ニコチン受容体;パーキンソン病;喫煙;SPECT, Nicotinic receptor;Parkinson's disease;smokin;SPECT

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16591202/
• Molecular imaging for noninvasive evaluation of atherosclerotic plaque vulnerability

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Hideo SAJI

  From 01 Apr. 2004, To 31 Mar. 2007, Project Closed

  血栓;不安定プラーク;分子イメージング;放射線検出器;グルコース誘導体;スカベンジャー受容体;マクロファージ;放射性プローブ;超小型放射線検出器;LOX-1;F-18, thrombosis;vulnerable plaque;molecular imaging;radiation detector;glucose derivative;lectine-like oxidized LDL receptor;macrophage;radiolabeled molecular probe

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16390337/
• 放射性機能分子を用いる遺伝子発現のインビボイメージング法の開発

  Grant-in-Aid for Exploratory Research

  Kyoto University

  佐治 英郎

  From 01 Apr. 2003, To 31 Mar. 2005, Project Closed

  遺伝子イメージング;インビボイメージング;心臓移植;免疫抑制遺伝子治療;インターロイキン-10;レポータ遺伝子;変異型ドパミンレセプター

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15659008/
• 分子イメージングによる核医学診断のための放射性医薬品の創薬戦略に関する研究

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  佐治 英郎

  From 01 Apr. 2003, To 31 Mar. 2004, Project Closed

  分子イメージング;遺伝子;タンパク質;受容体結合リガンド;コンピュータ解析;非侵襲的イメージング法;創薬;放射性医薬品

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15639010/
• In Vivo Imaging of β-Amyloid Plaques in Alzheimer's Disease Brains.

  Grant-in-Aid for Scientific Research (B)

  Nagasaki University

  Morio NAKAYAMA

  From 01 Apr. 2003, To 31 Mar. 2006, Project Closed

  アミロイドβ蛋白;分子イメージング;アルツハイマー病;PET;SPECT;フラボン;アミロイド;画像診断薬剤;テクネチウム-99m;フラボン誘導体;痴呆;神経変性疾患;放射性薬剤;画像化;老人斑アミロイド;インビボ画像化;放射性医薬品;放射性金属核種, amyloid β protein;molecular imaging;Alzheimer's disease;PET;SPECT;flavone

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15390014/
• 核酸合成・PG合成酵素のインビボイメージング:腫瘍・炎症の鑑別診断への挑戦

  Grant-in-Aid for Exploratory Research

  Kyoto University

  久下 裕司

  From 01 Apr. 2002, To 31 Mar. 2004, Project Closed

  インビボイメージング;腫瘍;炎症;鑑別診断;核酸合成;プロスタグランジン;チミジン;シクロオキシゲナーゼ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14657206/
• Molecular imaging and patho-functional analysis of cerebral ischemia : focused on prostaglandin synthases

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY

  Yuji KUGE

  From 01 Apr. 2002, To 31 Mar. 2005, Project Closed

  脳虚血病態;分子イメージング;プロスタグランジン;シクロオキシゲナーゼ(COX-2);ポジトロンCT(PET);シングルフォトンCT(SPECT);シクロオキシナーゼ(COX-2), pathophysiology of cerebral ischemia;molecular imaging;prostaglandins;cyclooxygenase-2(COX-2);positron CT (PET);single photon CT (SPECT)

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14370266/
• The evaluation of nicotinic acetylcholine receptors in patients with neurodegenerative disorders

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Hidenao FUKUYAMA

  From 01 Apr. 2002, To 31 Mar. 2005, Project Closed

  ニコチン受容体;神経変性疾患;喫煙;SPECT;定量解析;アルツハイマー病, Nicotinic receptor;neurodegenerative disorder;smoking;SPECT

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14370205/
• がんの内用放射線治療薬剤の開発研究

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  佐治 英郎

  From 01 Apr. 2001, To 31 Mar. 2002, Project Closed

  放射線治療薬;腫瘍;ターゲッティング;細胞殺傷作用;体内投与;線量当量

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13897020/
• 二官能性キレートによる放射性レニウム骨腫瘍治療薬剤の開発

  Grant-in-Aid for Exploratory Research

  Kyoto University

  佐治 英郎

  From 01 Apr. 2001, To 31 Mar. 2003, Project Closed

  骨疼痛緩和;ビスホスフォネート;放射性レニウム;放射線;細胞致死作用;二官能性キレート;体内動態;ヒドロキシアパタイト

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13877381/
• Re-186 Radiotherapeutical Agent for Bone Tumor Metastases and Bone Pain Palliation Radiotherapy

  Grant-in-Aid for Scientific Research (C)

  National Institue of Radiological Sciences;Kyoto University

  Satoshi FUKUDA

  From 01 Apr. 2001, To 31 Mar. 2003, Project Closed

  腫瘍の骨転移;家兎骨転移モデル;骨腫瘍診断薬剤;99mTc(V)-DMS;99mTc-HMDP;骨疼痛緩和;溶骨性骨腫瘍診断薬剤;99mTc(V)-HMDP, Bone metastases;Bone Metastases Model;Osteolytic Turner Diagnostic Agent;99mTc(V)-DMS;99mTc-HMDP;Bone Pain Palliation

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13670932/
• Development of a radioiodinated lipophilic cation as a new SPECT radiopharmaceutical for cancer diagnosis.

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Hideo SAJI

  From 01 Apr. 2001, To 31 Mar. 2004, Project Closed

  ミトコンドリア;膜電位;脂溶性カチオン;ロダシアニン誘導体;放射性ヨウ素;腫瘍;核医学診断薬;ログシアニン誘導体;脂溶性カオチン, mitochondria;membrane potentia;lipophilic cation;Rhodacyanine derivative;Radioiodine;tumor;radiopharmaceutical

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13470478/
• がんの内用放射線治療薬剤の開発研究

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  佐治 英郎

  From 01 Apr. 2000, To 31 Mar. 2001, Project Closed

  放射線治療薬;腫瘍;ターゲッティング;細胞殺傷作用;体内投与;線量当量

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12897024/
• Development of nonpeptidic opioid PET ligands to study pain system in the higher brain

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY

  Masamchi SATOH

  From 01 Apr. 2000, To 31 Mar. 2002, Project Closed

  PETリガンド;オピオイド受容体;carfentanil;痛覚情報伝達;イメージング;結合親和性;高選択性;内因性オピオイドペプチド, PET ligand;Opioid receptor;Carfentanil;Pain;Imaging;Binding activity;Endogenous ligand;Structure-activity relationships

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12557230/
• Development of in vivo dynamic and noninvasive imaging methodology of neurotransmission system with optically active radioligand.

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY

  Hideo SAJI

  From 01 Apr. 2000, To 31 Mar. 2002, Project Closed

  脳;ニコチン受容体;ノルアドレナリントランスポータ;光学異性体;放射性リガンド;画像解析;インビボマッピング;ラジオレセプターアッセイ, Brain;Nicotine receptor;Norepinephirine transporter;Opical isomer;Radioligand;In vivo imaging;In vivo mapping

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12557205/
• Pharmacological study on the role of amygdala in sensory and affective components of pain

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY

  Masamchi SATOH

  From 01 Apr. 2000, To 31 Mar. 2002, Project Closed

  扁桃体;痛覚受容;疼痛情動反応;モルヒネ;基底外側核;中心核;c-fos mRNA;グルタミン酸, Basolateral amygdala;Central amygdala;Affective component of pain;Pain;c-fos;Condtioned place aversion;Morphine;Glutamate

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12470498/
• がんの内用放射線治療薬剤の開発研究

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  佐治 英郎

  From 01 Apr. 1999, To 31 Mar. 2000, Project Closed

  放射線治療薬;腫瘍;ターゲッティング;細胞殺傷作用;体内投与;線量当量

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11897026/
• Development of optically active radioligand for biomedical imaging of neurotrasmission

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY

  Hideo SAJI

  From 01 Apr. 1998, To 31 Mar. 2000, Project Closed

  脳機能;ニコチン受容体;モノアミン酸化酵素;放射性機能分子;画像解析;インビボマッピング;ベンゾジアゼピンジアゼピン受容体;光学異性体;脳;放射性リガンド;ラジオレセプターアッセイ;体内分布;構造-活性相関;ポジトロンCT;シングルフォトンCT;酵素結合;脳局所分布, Brain;Nicotine receptor;Monoamine oxidase;Radioligand;Bioimaging;In vivo mapping;Benzodiazepine receptor;Optical isomer

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10470474/
• 高感度放射性機能探索分子の開発とそれによる神経受容体機能の画像解析

  Grant-in-Aid for Scientific Research on Priority Areas (A)

  Kyoto University

  佐治 英郎

  From 01 Apr. 1998, To 31 Mar. 1999, Project Closed

  ニコチンレセプター;インビボ画像解析;脳;光学異性体;レセプターマッピング;ラジオレセプターアッセイ

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10169231/
• 癌の内用放射線治療薬剤の開発研究

  Grant-in-Aid for Scientific Research (C)

  Kyoto University

  佐治 英郎

  From 01 Apr. 1997, To 31 Mar. 1998, Project Closed

  内用放射線治療;放射線治療薬;癌;ターゲティング;細胞殺傷作用

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09897015/
• Development of quantitative autoradiographic method for assessing fuctional imaging in living brain slices.

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY

  Hideo SAJI

  From 01 Apr. 1997, To 31 Mar. 1999, Project Closed

  脳機能;ラジオルミノグラフィ;イメージングプレート;生脳組織スライス;放射性リガンド;糖代謝;低酸素状態;ベンゾジアゼピンレセプター;画像解析;ラジオルミノグラフィー;放射性機能分子;スライス, brain;Bio-Imaging Analyzer;imaging plate;living slice;radiolabeled ligand;glucose metabolism;hypoxia;central benzodiazepine receptors

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09557189/
• Study on the molecular mechanisms for neuronal plasticicity in the drug dependence

  Grant-in-Aid for Scientific Research (B)

  KYOTO UNIVERSITY

  Masamchi SATOH

  From 01 Apr. 1997, To 31 Mar. 1999, Project Closed

  麻薬性鎮痛薬;オピオイド受容体;麻薬依存形成;アデニル酸シクラーゼ;過感受性;Gタンパク質;RGS4;slow depolarization;脱感作;RGS;可塑的神経機能変化;禁断症状;Ca^<2+>チャネル, opioid;opioid receptor;opioid dependence;adenylyl cyclase;supersensitization;G-protein;RGS4;slow depolarization

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09470503/
• In vivo investigation of brain nicotine receptors using optically active radioligand

  Grant-in-Aid for Scientific Research (C)

  KYOTO UNIVERSITY

  Hideo SAJI

  From 01 Apr. 1996, To 31 Mar. 1998, Project Closed

  ニコチン受容体;光学異性体;放射性薬剤;脳;アルツハイマー病;ラジオレセプターアッセイ;体内分布;レセプターマッピング;ニコチンレセプター;レセプターアッセイ;基底核;インビボマッピング;キラル化合物;放射性探索子;放射性医薬品, Nicotine receptor;Optical isomer;Radiopharmaceutical;Brain;Alzheimer's disease;Radioreceptor assay;Biodistribution;Receptor mapping

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08672474/
• Development of optically active radioligand for in vivo investigation of brain nicotine receptors.

  Grant-in-Aid for General Scientific Research (C)

  KYOTO UNIVERSITY

  Hideo SAJI

  From 01 Apr. 1994, To 31 Mar. 1996, Project Closed

  ニコチンレセプター;光学異性体;放射性薬剤;脳;放射性ヨウ素;ラジオレセプターアッセイ;体内分布;核医学;放射性医薬品;アルツハイマー病;老化;病態モデル動物;核医学診断, nicotine receptor;optical isomer;radiopharmaceutical;brain;radioiodine;nuclear medicine;biodistribution;radioreceptor assay

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-06672142/
• Study on the metabolism of Alzheimer's disease by PET

  Grant-in-Aid for General Scientific Research (C)

  KYOTO UNIVERSITY

  Hidenao FUKUYAMA

  From 01 Apr. 1993, To 31 Mar. 1995, Project Closed

  ポジトロンCT;アルツハイマー病;脳ブドウ糖代謝;血流代謝解離;脳酸素代謝, PET;Alzheimer's disease;Glucose Metabolism;Flow-metabolism uncoupling

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05670556/
• Studies on Non-invasive Measurement of Integrative Higher Brain Function and Disorders.

  Grant-in-Aid for General Scientific Research (B)

  KYOTO UNIVERSITY

  Y. YONEKURA

  From 01 Apr. 1991, To 31 Mar. 1993, Project Closed

  高次脳機能;無侵襲的計測法;ポジトロンCT;脳電図;脳磁図, Higher brain function;Non-invasive measurement;Positron emission tomography;Electroencephalography;Magnetoencephalography

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03454282/
• Stunned myocardiumの核医学的検討

  Grant-in-Aid for General Scientific Research (C)

  Kyoto University

  野原 隆司

  From 01 Apr. 1990, To 31 Mar. 1991, Project Closed

  Stunned myocardium;^<123>IーMetaiodobenzylguanidine;Sympathetic nerve;cathecolamine;PET;^<11>CーAcetate;^<++>Caー拮抗薬

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02807088/
• Basic and Clinical Studies for Quantitative Measurement of Myocardial Energy Metabolism Using Positron Emission Tomography.

  Grant-in-Aid for General Scientific Research (B)

  Kyoto University

  Junji KONISHI

  From 01 Apr. 1990, To 31 Mar. 1992, Project Closed

  ポジトロンCT;心筋;糖;脂肪酸;代謝;虚血性心疾患;心筋エネルギ-代謝;Fー18フルオロデオキシグルコ-ス;Cー11パルミチン酸;Cー11酢酸;糖代謝;脂肪酸代謝;酸素代謝, Positron emission tomography;Myocardium;Glucose;Latty acid;Metabolism;Coronary artery disease

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02454286/
• 心筋エネルギー代謝マッピングの臨床応用に関する研究

  Grant-in-Aid for General Scientific Research (C)

  Kyoto University

  米倉 義晴

  From 01 Apr. 1988, To 31 Mar. 1989, Project Closed

  心筋エネルギー代謝;核医学イメージング;陽電子放出断層法;単光子放出断層法

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63570490/
• Basic and Clinical Studies on Neuroreceptor Function by Radionuclide Approach

  Grant-in-Aid for General Scientific Research (B)

  KYOTO UNIVERSITY

  Junji KONISHI

  From 01 Apr. 1988, To 31 Mar. 1990, Project Closed

  受容体;核医学;ラジオアイソト-プ;ポジトロンCT;シングルフォトンエミッションCT;脳機能;オ-トラジオグラム;脳受容体;核医学イメージング;シングルフォトンECT;ラジオアイソトープ, receptor;nuclear medicine;radioisotope;positron emission tomography;single-photon emission computed tomography;brain function;autoradiogram

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63480250/
• Basic and Clinical Studies on Myocardial Metabolic Imaging.

  Grant-in-Aid for General Scientific Research (C)

  Kyoto University

  Yoshiharu YONEKURA

  From 01 Apr. 1986, To 31 Mar. 1988, Project Closed

  心筋代謝;心筋虚血;ポジトロンCT;核医学;イメージング;グルコース;ポジトロン断層法;ラジオアイソトープ, Myocardial Metabolism;Myocardial Ischemia;Positron Emission Computed Tomography;Nuclear Medicine;Imaging

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-61570511/
• Research on positron emitting 62-zinc and 62-copper radiopharmaceuticals for Nuclear Medicine.

  Grant-in-Aid for Developmental Scientific Research

  Kyoto University

  Akira YOKOYAMA

  From 01 Apr. 1985, To 31 Mar. 1987, Project Closed

  62-亜鉛;62-銅;エチレンジアミン二酢酸錯体;二官能性キレート;心筋診断;膵機能診断;膵臓がん診断;ジェネレータ;62-銅標識放射性医薬品;62-亜鉛標識放射性医薬品;二官能性錯体;心筋診断薬剤;膵臓診断薬剤;エチレンジアミン二酢酸亜鉛錯体;がん診断薬剤, 62-zinc;62-copper;ethylenediamine-N,N'diacetate complex;bifunctional chelate;myocardial diagnosis;functional diagnosis of pancreas;neoplastic pancreas diagnosis

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-60870080/
• Basic and Clinical Studies on Diagnosis of Cardiovascular Disease Using Positron Emission Tomography.

  Grant-in-Aid for General Scientific Research (B)

  Fukui Medical School;Kyoto University

  Torizuka KANJI

  From 01 Apr. 1985, To 31 Mar. 1987, Project Closed

  ポジトロンCT;核医学;心筋血流;心筋代謝;心筋虚血;循環器病診断, positron emission tomography;nuclear medicine;myocardial perfusion;myocardial metabolism;myocardial ischemia

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-60480255/

External funds: others

• Study on Radiopharmaceuticals
• In vivo quantitative noninvasive analysis of pathological function
• Study on Bioactive Metal Compound

Education

Teaching subject(s)

• From Apr. 2011, To Mar. 2012

  分析学II（放射化学）

  Fall, 薬学部
• From Apr. 2011, To Mar. 2012

  放射性医薬品学

  Spring, 薬学部
• From Apr. 2011, To Mar. 2012

  特別実習（病態機能分析学）

  Year-long, 薬学部
• From Apr. 2011, To Mar. 2012

  分析化学２（放射化学）

  Fall, 薬学部
• From Apr. 2011, To Mar. 2012

  分析化学４（臨床化学）

  Spring, 薬学部
• From Apr. 2011, To Mar. 2012

  特別実習[病態機能分析学]

  Year-long, 薬学部
• From Apr. 2011, To Mar. 2012

  Introduction to Basic Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2011, To Mar. 2012

  創薬物理化学エクササイズ２

  Fall, 薬学部
• From Apr. 2011, To Mar. 2012

  Basic Laboratory Techniques in Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Basic Laboratory Techniques in Physical Chemistry

  Fall, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Advanced Basic Physical Chemistry II

  Spring, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2011, To Mar. 2012

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2011, To Mar. 2012

  臨床薬学総論

  Fall, 薬学部
• From Apr. 2012, To Mar. 2013

  Analytical Chemistry 2 (Radiochemistry)

  Fall, 薬学部
• From Apr. 2012, To Mar. 2013

  Analytical Chemistry 4 (Clinical Chemistry)

  Spring, 薬学部
• From Apr. 2012, To Mar. 2013

  Analytical Chemistry II(Radiochemistry)

  Fall, 薬学部
• From Apr. 2012, To Mar. 2013

  Medicinal Physical Chemistry Exercise 2

  Fall, 薬学部
• From Apr. 2012, To Mar. 2013

  Physical Sciences for Drug Discovery

  Spring, 全学共通科目
• From Apr. 2012, To Mar. 2013

  doctoral program

  Spring, 薬学研究科
• From Apr. 2012, To Mar. 2013

  doctoral program

  Fall, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Basic Laboratory Techniques in Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Basic Laboratory Techniques in Physical Chemistry

  Fall, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Introduction to Basic Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Advanced Basic Physical Chemistry I

  Spring, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Radiopharmacology

  Spring, 薬学部
• From Apr. 2012, To Mar. 2013

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2012, To Mar. 2013

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2012, To Mar. 2013

  Introduction to Clinical Pharmacy

  Fall, 薬学部
• From Apr. 2012, To Mar. 2013

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Introduction to Pharmaceutical Sciences

  Spring, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2012, To Mar. 2013

  Advanced Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2013, To Mar. 2014

  Analytical Chemistry 2 (Radiochemistry)

  Fall, 薬学部
• From Apr. 2013, To Mar. 2014

  Analytical Chemistry 4 (Clinical Chemistry)

  Spring, 薬学部
• From Apr. 2013, To Mar. 2014

  Medicinal Physical Chemistry Exercise 2

  Fall, 薬学部
• From Apr. 2013, To Mar. 2014

  Introduction to Clinical Pharmacy

  Fall, 薬学部
• From Apr. 2013, To Mar. 2014

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2013, To Mar. 2014

  Introduction to Basic Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Basic Laboratory Techniques in Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Basic Laboratory Techniques in Physical Chemistry

  Fall, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Advanced Basic Physical Chemistry II

  Spring, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Introduction to Pharmaceutical Sciences

  Spring, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Advanced Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2013, To Mar. 2014

  doctoral program

  Spring, 薬学研究科
• From Apr. 2013, To Mar. 2014

  doctoral program

  Fall, 薬学研究科
• From Apr. 2013, To Mar. 2014

  Physical Sciences for Drug Discovery

  Spring, 全学共通科目
• From Apr. 2014, To Mar. 2015

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2014, To Mar. 2015

  Analytical Chemistry 2 (Radiochemistry)

  Fall, 薬学部
• From Apr. 2014, To Mar. 2015

  Analytical Chemistry 4 (Clinical Chemistry)

  Spring, 薬学部
• From Apr. 2014, To Mar. 2015

  Medicinal Physical Chemistry Exercise 2

  Fall, 薬学部
• From Apr. 2014, To Mar. 2015

  Introduction to Clinical Pharmacy

  Fall, 薬学部
• From Apr. 2014, To Mar. 2015

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2014, To Mar. 2015

  Introduction to Basic Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Basic Laboratory Techniques in Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Basic Laboratory Techniques in Physical Chemistry

  Fall, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Advanced Basic Physical Chemistry I

  Spring, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Introduction to Pharmaceutical Sciences

  Spring, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Advanced Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2014, To Mar. 2015

  Physical Sciences for Drug Discovery

  Spring, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Analytical Chemistry 2 (Radiochemistry)

  Fall, 薬学部
• From Apr. 2015, To Mar. 2016

  Analytical Chemistry 4 (Clinical Chemistry)

  Spring, 薬学部
• From Apr. 2015, To Mar. 2016

  Medicinal Physical Chemistry Exercise 2

  Fall, 薬学部
• From Apr. 2015, To Mar. 2016

  Basic Laboratory Techniques in Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Basic Laboratory Techniques in Physical Chemistry

  Fall, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Introduction to Basic Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Advanced Basic Physical Chemistry II

  Spring, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2015, To Mar. 2016

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2015, To Mar. 2016

  Introduction to Clinical Pharmacy

  Fall, 薬学部
• From Apr. 2015, To Mar. 2016

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Introduction to Pharmaceutical Sciences

  Spring, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2015, To Mar. 2016

  Advanced Pharmaceutical Sciences II

  Spring, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Analytical Chemistry 2 (Radiochemistry)

  Fall, 薬学部
• From Apr. 2016, To Mar. 2017

  Analytical Chemistry 4 (Clinical Chemistry)

  Spring, 薬学部
• From Apr. 2016, To Mar. 2017

  Medicinal Physical Chemistry Exercise 2

  Fall, 薬学部
• From Apr. 2016, To Mar. 2017

  Basic Laboratory Techniques in Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Basic Laboratory Techniques in Physical Chemistry

  Fall, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Introduction to Basic Physical Chemistry

  Spring, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Advanced Basic Physical Chemistry I

  Spring, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Laboratory Practice in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Research in Basic Pharmacodynanic Sciences

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Seminar in Basic Patho-Functional Analysis

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2016, To Mar. 2017

  Research Training(Patho-functional Bioanalysis)

  Year-long, 薬学部
• From Apr. 2016, To Mar. 2017

  Interdisciplinary Sciences

  Fall, 全学共通科目
• From Apr. 2016, To Mar. 2017

  Introduction to Clinical Pharmacy

  Fall, 薬学部
• From Apr. 2016, To Mar. 2017

  Research in Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Research in Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Research in Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Introduction to Pharmaceutical Sciences

  Spring, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Seminar for Pharmaceutical Sciences III

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Seminar for Pharmaceutical Sciences II

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Seminar for Pharmaceutical Sciences I

  Year-long, 薬学研究科
• From Apr. 2016, To Mar. 2017

  Advanced Pharmaceutical Sciences II

  Spring, 薬学研究科

Administration

School management (title, position)

• From 01 Apr. 2010, To 31 Mar. 2011

  核燃料物質管理委員会 委員
• From 01 Apr. 2010, To 31 Mar. 2011

  産官学連携本部運営協議会 委員
• From 01 Apr. 2008, To 31 Mar. 2011

  放射性同位元素等管理委員会 委員長
• From 01 Apr. 2008, To 30 Apr. 2010

  環境・安全・衛生委員会 委員
• From 01 May 2008, To 31 Mar. 2011

  全学情報セキュリティ委員会 委員
• From 01 Apr. 2009, To 31 Mar. 2011

  大学評価委員会 委員
• From 01 Apr. 2010, To 31 Mar. 2011

  保健衛生委員会 委員
• From 01 Apr. 2010, To 31 Mar. 2011

  吉田キャンパス整備専門委員会委員会 委員
• From 01 Apr. 2010, To 31 Mar. 2011

  情報環境整備委員会 委員
• From 01 Apr. 2010, To 31 Mar. 2011

  施設整備委員会 委員
• From 01 Apr. 2008, To 31 Mar. 2010

  教育制度委員会 委員
• From 01 Apr. 2008, To 30 Jan. 2010

  教職教育委員会 委員
• From 01 Apr. 2010, To 31 Mar. 2011

  全学共通教育委員会 委員
• From 01 Nov. 2008, To 30 Apr. 2010

  副理事
• From 01 Apr. 2008, To 30 Sep. 2010

  環境安全保健機構長
• From 01 Apr. 2011, To 31 Mar. 2012

  総長選考会議委員
• From 01 Apr. 2011, To 31 Mar. 2012

  京都大学施設整備委員会 委員
• From 01 Apr. 2011, To 31 Mar. 2013

  全学共通教育委員会 委員
• From 01 Apr. 2011, To 31 Mar. 2013

  全学情報セキュリティ委員会 委員
• From 01 Apr. 2011, To 31 Mar. 2013

  大学評価委員会 委員
• From 01 Apr. 2011, To 31 Mar. 2013

  産官学連携本部運営協議会
• From 01 Apr. 2011, To 31 Mar. 2012

  研究科長部会
• From 01 Apr. 2011, To 31 Mar. 2012

  総長選考会議委員会 委員
• From 01 Apr. 2011, To 31 Mar. 2013

  評議員
• From 01 Apr. 2011, To 31 Mar. 2012

  部局長会議
• From 01 Feb. 2012, To 30 Sep. 2012

  博士課程教育リーディングプログラム実施準備委員会 委員
• From 01 Apr. 2012, To 31 Mar. 2013

  京都大学全学共通教育実施体制等特別委員会 委員
• From 01 Apr. 2012, To 31 Mar. 2014

  人事審査委員会 委員
• From 01 May 2012, To 31 Mar. 2013

  研究科長部会
• From 01 May 2012, To 31 Mar. 2013

  部局長会議
• From 01 Oct. 2012, To 30 Sep. 2014

  京都大学財務委員会 委員
• From 01 Oct. 2012, To 31 Mar. 2014

  京都大学総長選考会議
• From 01 Apr. 2013, To 31 Mar. 2014

  研究科長部会議
• From 01 Apr. 2013, To 31 Mar. 2014

  国際高等教育院教養・共通教育協議会 委員
• From 01 Apr. 2013, To 31 Mar. 2014

  産官学連携本部運営協議会
• From 01 Apr. 2010, To 31 Mar. 2014

  全学情報セキュリティ委員会 委員
• From 01 Apr. 2010, To 31 Mar. 2014

  大学評価委員会 委員
• From 01 Apr. 2010, To 31 Mar. 2014

  博士課程教育リーディングプログラム運営会議 委員
• From 01 Apr. 2010, To 31 Mar. 2014

  評議員
• From 01 Apr. 2010, To 31 Mar. 2014

  部局長会議
• From 01 Apr. 2013, To 31 Mar. 2015

  原子力研究整備委員会 委員
• From 02 Jul. 2012, To 31 Mar. 2014

  教育研究組織改革専門委員会 委員
• From 01 Oct. 2014, To 30 Sep. 2016

  吉田キャンパス整備専門委員会 2号委員
• From 01 Oct. 2014, To 30 Sep. 2016

  施設整備委員会 6号委員
• From 01 Apr. 2015, To 31 Mar. 2016

  教育制度委員会 委員
• From 01 Apr. 2015, To 31 Mar. 2016

  教育制度委員会WG１ 委員
• From 01 Apr. 2015, To 31 Mar. 2016

  教育制度委員会WG2 委員
• From 01 Apr. 2010, To 31 Mar. 2014

  薬学研究科長
• From 01 Apr. 2010, To 31 Mar. 2014

  薬学部長
• From 01 Apr. 2010, To 31 Mar. 2014

  薬学研究科附属薬用植物園長
• From 01 Apr. 2016, To 30 Sep. 2016

  理事補
• From 01 Apr. 2016, To 31 Mar. 2017

  研究倫理・安全推進委員会 委員
• From 01 Apr. 2016, To 31 Mar. 2017

  京都大学研究公正委員会 委員
• From 01 Apr. 2017

  大学評価委員会 委員
• From 01 Apr. 2016

  全学情報セキュリティ委員会 委員
• From 01 Apr. 2017, To 30 Sep. 2018

  理事補
• From 01 Apr. 2016

  研究公正委員会 委員
• From 01 Jul. 2014, To 30 Apr. 2016

  国際高等教育院 企画評価専門委員会 物理学部会 委員
• From 01 Apr. 2017, To 30 Sep. 2020

  理事補
• From 01 Oct. 2018, To 30 Sep. 2020

  国際戦略本部運営協議会　全学海外拠点運営専門部会 部会員
• From 01 Oct. 2018, To 30 Sep. 2020

  国際戦略本部運営協議会　パートナーシップ専門部会 部会員
• From 01 Apr. 2016, To 31 Mar. 2019

  研究公正委員会 委員
• From 01 Oct. 2020, To 30 Sep. 2022

  国際戦略本部運営協議会 協議員
• From 10 Dec. 2020, To 30 Sep. 2022

  国際戦略本部運営協議会　全学海外拠点運営専門部会 部会員
• From 28 Oct. 2020, To 30 Sep. 2022

  研究戦略タスクフォース プログラムディレクター