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Chinnathambi, Shanmugavel

Institute for Advanced Study Program-Specific Researcher

Chinnathambi, Shanmugavel
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    Last Updated :2023/05/26

    Basic Information

    Email Address

    • Email Address

      chinnathambi.shanmugavel.8skyoto-u.ac.jp

    Professional Memberships

    • From Oct. 2017, To Present
      Indian JSPS Alumni Association

    Academic Degree

    • 30 Apr. 2007
      M.Sc(University of Madras)
    • 05 Nov. 2014
      Ph.D(Anna University)

    Academic Resume (Graduate Schools)

    • Anna University, Medical Physics,Biomaterials,Ph.D, 修了
    • University of Madras, Department of Crystallography and Biophysics, 修了

    Academic Resume (Undergraduate School/Majors)

    • Periyar Arts College, B.Sc in Physics, 卒業
    • NLC Boys Higer Secondary School, 卒業

    Research History

    • From Mar. 2020, To Present
      Kyoto University, Institute for Integrated Cell - Material Sciences
    • From Feb. 2018, To Feb. 2020
      National Institute for Materials Science, International Center for Young Scientists
    • From Oct. 2015, To Sep. 2017
      JSPS Postdoctoral Research Fellow
    • From Feb. 2015, To Sep. 2015
      National Institute for Materials Science, Nanotechnology Innovation Station

    ID,URL

    Website(s) (URL(s))

    researchmap URL

    list
      Last Updated :2023/05/26

      Research

      Research Interests

      • Silica Nanoparticles, Quantum dots, Drug delivery

      Research Areas

      • Nanotechnology/Materials, Nanobioscience, Quantum dots

      Papers

      • A biophysical approach of tyrphostin AG879 binding information in: bovine serum albumin, human ErbB2, c-RAF1 kinase, SARS-CoV-2 main protease and angiotensin-converting enzyme 2
        Subramani Karthikeyan; Anandh Sundaramoorthy; Saravanan Kandasamy; Ganesan Bharanidharan; Prakasarao Aruna; Ramakrishnamurthy Suganya; Rajendiran Mangaiyarkarasi; Singaravelu Ganesan; Ganesh N. Pandian; Anitha Ramamoorthi; Shanmugavel Chinnathambi
        Journal of Biomolecular Structure and Dynamics, 28 Apr. 2023, Peer-reviewed, Corresponding author
      • A review on medicinally important heterocyclic compounds and importance of biophysical approach of underlying the insight mechanism in biological environment
        Subramani Karthikeyan; Maria Grishina; Saravanan Kandasamy; Rajendiran Mangaiyarkarasi; Anitha Ramamoorthi; Shanmugavel Chinnathambi; Ganesh N. Pandian; L. John Kennedy
        Journal of Biomolecular Structure and Dynamics, 13 Mar. 2023, Peer-reviewed
      • Nano–bio interaction between human immunoglobulin G and nontoxic, near-infrared emitting water-borne silicon quantum dot micelles
        Shanmugavel Chinnathambi; Naoto Shirahata; Mahima Kumar; Subramani Karthikeyan; Katsuhiko Abe; Vaijayanthi Thangavel; Ganesh N. Pandian
        RSC Advances, Feb. 2023, Peer-reviewed, Lead author, Corresponding author
      • A biophysical approach of cytarabine anticancer drug insights into human serum albumin and checkpoint kinase 1
        Manoharan Rupavarshini; Subramani Karthikeyan; Sundaramoorthy Anandh; Anitha Ramamoorthi; Suganya Ramakrishnamurthy; Ganesan Bharanidharan; Prakasarao Aruna; Rajendiran Mangaiyarkarasi; Shanmugavel Chinnathambi; Ganesh N. Pandian; Singaravelu Ganesan
        Results in Chemistry, Jan. 2023, Peer-reviewed
      • Facile Synthesis of Hafnium Oxide Nanoparticle Decorated on Graphene Nanosheet and Its Photocatalytic Degradation of Organic Pollutants under UV-Light Irradiation
        Venkatachalam Jayaraman; Shanmugam Mahalingam; Shanmugavel Chinnathambi; Ganesh N. Pandian; Aruna Prakasarao; Singaravelu Ganesan; Jayavel Ramasamy; Sivasankaran Ayyaru; Young-Ho Ahn
        Applied Sciences, 05 Nov. 2022, Peer-reviewed, Corresponding author
      • Iodine containing porous organosilica nanoparticles trigger tumor spheroids destruction upon monochromatic X-ray irradiation: DNA breaks and K-edge energy X-ray
        Yuya Higashi; Kotaro Matsumoto; Hiroyuki Saitoh; Ayumi Shiro; Yue Ma; Mathilde Laird; Shanmugavel Chinnathambi; Albane Birault; Tan Le Hoang Doan; Ryo Yasuda; Toshiki Tajima; Tetsuya Kawachi; Fuyuhiko Tamanoi
        Scientific Reports, Jul. 2021, Peer-reviewed
      • A Compact Sensory Platform Based pH Sensor Using Graphene Field Effect Transistor
        Kumar Manoharan, Arun; Jayavel, Ramasamy; Shanmugam, Mahalingam; Sengottaiyan, Chinnasamy; Chinnathambi, Shanmugavel; Mohankumar, Nagarajan
        Journal of Nanoscience and Nanotechnology, Jun. 2021, Peer-reviewed
      • A pilot study on parallel factor analysis as a diagnostic tool for oral cancer diagnosis: A statistical modeling approach
        Udayakumar Kanniyappan; Einstein Gnanatheepam; Karthikeyan Subramani; Mangaiyarkarasi Rajendran; Shanmugavel Chinnathambi; Prakasarao Aruna; Singaravelu Ganesan
        Journal of Chemometrics, Mar. 2021, Peer-reviewed
      • Construction of Boronophenylalanine-Loaded Biodegradable Periodic Mesoporous Organosilica Nanoparticles for BNCT Cancer Therapy
        Fuyuhiko Tamanoi; Shanmugavel Chinnathambi; Mathilde Laird; Aoi Komatsu; Albane Birault; Takushi Takata; Tan Le-Hoang Doan; Ngoc Xuan Dat Mai; Arthur Raitano; Kendall Morrison; Minoru Suzuki; Kotaro Matsumoto
        International Journal of Molecular Sciences, 24 Feb. 2021, Peer-reviewed
      • Nano-Bio Interaction between Blood Plasma Proteins and Water-Soluble Silicon Quantum Dots with Enabled Cellular Uptake and Minimal Cytotoxicity
        Shanmugavel Chinnathambi; Nobutaka Hanagata; Tomohiko Yamazaki; Naoto Shirahata
        Nanomaterials, 13 Nov. 2020, Peer-reviewed, Lead author, Corresponding author
      • Recent Development to Explore the Use of Biodegradable Periodic Mesoporous Organosilica (BPMO) Nanomaterials for Cancer Therapy
        Shanmugavel Chinnathambi; Fuyuhiko Tamanoi
        Pharmaceutics, 18 Sep. 2020, Peer-reviewed, Lead author
      • Recent advances on fluorescent biomarkers of near-infrared quantum dots for in vitro and in vivo imaging
        Shanmugavel Chinnathambi; Naoto Shirahata
        Science and Technology of Advanced Materials, 31 Dec. 2019, Peer-reviewed, Lead author
      • Facile Formation of Stable Water‐Dispersed Luminescent Silicon Nanocrystals by Laser Processing in Liquid: Toward Fluorescent Labeling for Bio‐Imaging
        Ze Yuan; Toshihiro Nakamura; Shanmugavel Chinnathambi; Yanbai Pu; Naoto Shirahata; Kiyoto Matsuishi
        ChemNanoMat, Sep. 2019, Peer-reviewed
      • Quercetin loaded PLGA microspheres induce apoptosis in breast cancer cells
        V. Karthick; Sucheta Panda; V. Ganesh Kumar; Dinesh Kumar; Lok Kumar Shrestha; Katsuhiko Ariga; K. Vasanth; Shanmugavel Chinnathambi; T. Stalin Dhas; K.S. Uma Suganya
        Applied Surface Science, Sep. 2019, Peer-reviewed
      • Photostability of quantum dot micelles under ultraviolet irradiation
        Shanmugavel Chinnathambi; Nobutaka Hanagata
        Luminescence, Aug. 2019, Peer-reviewed, Lead author, Corresponding author
      • Exploring the Binding Interaction Mechanism of Taxol in β-Tubulin and Bovine Serum Albumin: A Biophysical Approach
        Subramani Karthikeyan; Ganesan Bharanidharan; Sriram Ragavan; Saravanan Kandasamy; Shanmugavel Chinnathambi; Kanniyappan Udayakumar; Rajendiran Mangaiyarkarasi; Ramakrishnamurthy Suganya; Prakasarao Aruna; Singaravelu Ganesan
        Molecular Pharmaceutics, 04 Feb. 2019, Peer-reviewed
      • Comparative Binding Analysis ofN-Acetylneuraminic Acid in Bovine Serum Albumin and Human α-1 Acid Glycoprotein
        Subramani Karthikeyan; Ganesan Bharanidharan; Sriram Ragavan; Saravanan Kandasamy; Shanmugavel Chinnathambi; Kanniyappan Udayakumar; Rajendiran Mangaiyarkarasi; Anandh Sundaramoorthy; Prakasarao Aruna; Singaravelu Ganesan
        Journal of Chemical Information and Modeling, 28 Jan. 2019, Peer-reviewed
      • Molecular interaction of silicon quantum dot micelles with plasma proteins: hemoglobin and thrombin
        Shanmugavel Chinnathambi; Subramani Karthikeyan; Nobutaka Hanagata; Naoto Shirahata
        RSC Advances, 2019, Peer-reviewed, Lead author, Corresponding author
      • 4-Hydroxycoumarin Derivative:N-(diphenylmethyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide Interaction with Human Serum Albumin
        Shanmugavel Chinnathambi; Subramani Karthikeyan; Mangaiyarkarsi Rajendiran; Kanniyappan Udayakumar; Arunkumar Manoharan; Saravanan Kandasamy; Nobutaka Hanagata
        Journal of Spectroscopy, 16 Oct. 2018, Peer-reviewed, Lead author, Corresponding author
      • Inverted Device Architecture for Enhanced Performance of Flexible Silicon Quantum Dot Light-Emitting Diode
        Batu Ghosh; Hiroyuki Yamada; Shanmugavel Chinnathambi; İrem Nur Gamze Özbilgin; Naoto Shirahata
        The Journal of Physical Chemistry Letters, 20 Sep. 2018, Peer-reviewed
      • A cytotoxicity, optical spectroscopy and computational binding analysis of 4-[3-acetyl-5-(acetylamino)-2-methyl-2,3-dihydro-1,3,4-thiadiazole-2-yl]phenyl benzoate in calf thymus DNA
        Subramani Karthikeyan; Ganesan Bharanidharan; Rajendiran Mangaiyarkarasi; Shanmugavel Chinnathambi; Ragavan Sriram; Krishnaswamy Gunasekaran; Kandasamy Saravanan; Mani Gopikrishnan; Prakasarao Aruna; Singaravelu Ganesan
        Luminescence, Jun. 2018, Peer-reviewed
      • Simplified detection of the hybridized DNA using a graphene field effect transistor
        Arun Kumar Manoharan; Shanmugavel Chinnathambi; Ramasamy Jayavel; Nobutaka Hanagata
        Science and Technology of Advanced Materials, 31 Dec. 2017, Peer-reviewed
      • Synthesis, Cytotoxicity and Antitumor Activity of 4-[(1-(2-carbamothioylhydrazinylidene)ethyl]phenyl acetate (acesemi) Conjugated Chitosan Functionalized LaF3:Ce3+, Tb3+ Nanoparticles
        Rajendiran Mangaiyarkarasi; Shanmugavel Chinnathambi; Karthikeyan Subramani; Prakasarao Aruna; Singaravelu Ganesan
        Journal of Nanoscience and Nanotechnology, 01 Aug. 2017, Corresponding author
      • Synthesis and fast transfer of monolayer MoS2 on reusable fused silica
        Tao Liang; Shuang Xie; Weifei Fu; Yu Cai; Chinnathambi Shanmugavel; Hideo Iwai; Daisuke Fujita; Nobutaka Hanagata; Hongzheng Chen; Mingsheng Xu
        Nanoscale, 2017, Peer-reviewed
      • Biocompatible CdSe/ZnS quantum dot micelles for long-term cell imaging without alteration to the native structure of the blood plasma protein human serum albumin
        Shanmugavel Chinnathambi; Norhidayah Abu; Nobutaka Hanagata
        RSC Advances, 2017, Peer-reviewed, Lead author
      • Paclitaxel conjugated Fe3O4@LaF3:Ce3+,Tb3+ nanoparticles as bifunctional targeting carriers for Cancer theranostics application
        Rajendiran Mangaiyarkarasi; Shanmugavel Chinnathambi; Subramani Karthikeyan; Prakasarao Aruna; Singaravelu Ganesan
        Journal of Magnetism and Magnetic Materials, Feb. 2016, Peer-reviewed
      • Underlying the Mechanism of 5-Fluorouracil and Human Serum Albumin Interaction: A Biophysical Study
        Shanmugavel Chinnathambi; Subramani Karthikeyan, Manish Kesherwani, Devadasan Velmurugan and Nobutaka Hanagata
        Journal of Physical Chemistry & Biophysics, 2016, Peer-reviewed, Lead author
      • Regulation of bifurcated cytokine induction by surface charge of nanoparticles during interaction between CpG oligodeoxynucleotides and toll-like receptor 9
        Shanmugavel Chinnathambi; Xiaodong Pi; Mingsheng Xu; Nobutaka Hanagata
        Journal of Drug Delivery Science and Technology, Oct. 2015, Peer-reviewed, Lead author
      • Investigation of Optical Spectroscopic and Computational Binding Mode of Bovine Serum Albumin with 1, 4-Bis ((4-((4-Heptylpiperazin-1-yl) Methyl)-1H-1, 2, 3-Triazol-1-yl) Methyl) Benzene
        Subramani Karthikeyan; Shanmugavel Chinnathambi; Ayyavoo Kannan; Perumal Rajakumar; Devadasan Velmurugan; Ganesan Bharanidharan; Prakasarao Aruna; Singaravelu Ganesan
        Journal of Biochemical and Molecular Toxicology, Aug. 2015, Peer-reviewed
      • Investigations on the Interactions of 5-Fluorouracil with Herring Sperm DNA: Steady State/Time Resolved and Molecular Modeling Studies
        Shanmugavel Chinnathambi; Subramani Karthikeyan; Devadasan Velmurugan; Nobutaka Hanagata; Prakasarao Aruna; Singaravelu Ganesan
        Biophysical Reviews and Letters, Jun. 2015, Peer-reviewed, Lead author
      • Synthesis of 5-Fluorouracil conjugated LaF3:Tb3+/PEG-COOH nanoparticles and its studies on the interaction with bovine serum albumin: spectroscopic approach
        Rajendiran Mangaiyarkarasi; Shanmugavel Chinnathambi; Prakasarao Aruna; Singaravelu Ganesan
        Journal of Nanoparticle Research, Mar. 2015, Peer-reviewed
      • Synthesis and formulation of methotrexate (MTX) conjugated LaF3:Tb3+/chitosan nanoparticles for targeted drug delivery applications
        Rajendiran Mangaiyarkarasi; Shanmugavel Chinnathambi; Prakasarao Aruna; Singaravelu Ganesan
        Biomedicine & Pharmacotherapy, Feb. 2015, Peer-reviewed
      • Effect of Moderate UVC Irradiation on Bovine Serum Albumin and Complex with Antimetabolite 5-Fluorouracil: Fluorescence Spectroscopic and Molecular Modelling Studies
        Shanmugavel Chinnathambi; Subramani Karthikeyan; Devadasan Velmurugan; Nobutaka Hanagata; Prakasarao Aruna; Singaravelu Ganesan
        International Journal of Spectroscopy, 31 Jan. 2015, Peer-reviewed, Lead author
      • Insights into the Binding of 3-(1-Phenylsulfonyl-2-methylindol-3-ylcarbonyl) Propanoic Acid to Bovine Serum Albumin: Spectroscopy and Molecular Modelling Studies
        Subramani Karthikeyan; Shanmugavel Chinnathambi; Devadasan Velmurugan; Ganesan Bharanidharan; Singaravelu Ganesan
        Nano Biomedicine and Engineering, 10 Jan. 2015, Peer-reviewed
      • Synthesis and characterization of hafnium oxide nanoparticles for bio-safety
        Venkatachalam Jayaraman; Ganesan Bhavesh; Shanmugavel Chinnathambi; Singaravelu Ganesan; Prakasarao Aruna
        Materials Express, 01 Oct. 2014, Peer-reviewed
      • Investigations on the interactions of 5-fluorouracil with bovine serum albumin: Optical spectroscopic and molecular modeling studies
        Shanmugavel Chinnathambi; Devadasan Velmurugan; Nobutaka Hanagata; Prakasa Rao Aruna; Singaravelu Ganesan
        Journal of Luminescence, Jul. 2014, Peer-reviewed, Lead author
      • Silicon Quantum Dots for Biological Applications
        Shanmugavel Chinnathambi; Song Chen; Singaravelu Ganesan; Nobutaka Hanagata
        Advanced Healthcare Materials, Jan. 2014, Peer-reviewed, Lead author
      • Large-Scale Fabrication of Free-Standing, Micropatterned Silica Nanotubes Via a Hybrid Hydrogel-Templated Route
        Song Chen; Xuetao Shi; Shanmugavel Chinnathambi; Nobutaka Hanagata
        Advanced Healthcare Materials, Aug. 2013, Peer-reviewed
      • Synthesis of novel chitosan–silica/CpG oligodeoxynucleotide nanohybrids with enhanced delivery efficiency
        Song Chen; Huijie Zhang; Shanmugavel Chinnathambi; Nobutaka Hanagata
        Materials Science and Engineering: C, Aug. 2013, Peer-reviewed
      • Generation of microgrooved silica nanotube membranes with sustained drug delivery and cell contact guidance ability by using a Teflon microfluidic chip
        Song Chen; Xuetao Shi; Shanmugavel Chinnathambi; Hongkai Wu; Nobutaka Hanagata
        Science and Technology of Advanced Materials, Mar. 2013, Peer-reviewed
      • Binding Mode of CpG Oligodeoxynucleotides to Nanoparticles Regulates Bifurcated Cytokine induction via Toll-like Receptor 9
        Shanmugavel Chinnathambi; Song Chen; Singaravelu Ganesan; Nobutaka Hanagata
        Scientific Reports, Dec. 2012, Peer-reviewed, Lead author
      • Effect of molecular weight of polyethyleneimine on loading of CpG oligodeoxynucleotides onto flake-shell silica nanoparticles for enhanced TLR9-mediated induction of interferon-α
        Manoharan; Qingmin Ji; Yamazaki; Shanmugavel Chinnathambi; Chen; Ganesan; Hill; Ariga:Nobutaka Hanagata
        International Journal of Nanomedicine, Jul. 2012, Peer-reviewed
      • Fabrication of novel collagen-silica hybrid membranes with tailored biodegradation and strong cell contact guidance ability
        Song Chen; Shanmugavel Chinnathambi; Xuetao Shi; Akiyoshi Osaka; Yufang Zhu; Nobutaka Hanagata
        Journal of Materials Chemistry, 2012, Peer-reviewed

      Presentations

      • Silica / Silicon nanoparticles for biomedical applications
        Shanmugavel Chinnathambi
        Department of Physics, Meenakshi college of engineering, Chennai-78, India, 09 Jan. 2021, Invited
      • Quantum dots for biomedical applications
        Shanmugavel Chinnathambi
        ICNAN 2019, VIT University, Vellore, India
      • Quantum dots for biomedical applications
        Shanmugavel Chinnathambi
        Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto, Japan, 21 Nov. 2019
      • Quantum dots for biomedical applications
        Shanmugavel Chinnathambi
        Centre for nanotechnology research, VIT University, Vellore, India, 14 Oct. 2019
      • Biomedical applications of water-soluble quantum dots
        Shanmugavel Chinnathambi
        12th International Symposium on Nanomedicine (ISNM 2018), Yamaguchi University, Japan, Invited
      • Semiconductor quantum dot for biomedical applications
        Shanmugavel Chinnathambi
        SIRIM-WAITRO International Conference (SWIC) 2018, Penang, Malaysia
      • Silicon quantum dot micelles interaction with blood plasma proteins
        Shanmugavel Chinnathambi
        International Conference on Emerging Advanced Nanomaterials (ICEAN), Newcastle, Australia, Invited
      • Quantum Dots for Biological Applications
        Shanmugavel Chinnathambi
        Sri Sarada Mahavidyalayam Arts and Science College for Women, India, 05 Jan. 2018, Invited
      • Magnetic CdSe/ZnS Quantum Dot Micelles for In Vitro Cancer Cell Imaging
        Shanmugavel Chinnathambi
        Advanced Materials Conference, Langkawi, Malaysia
      • Superparamagnetic CdSe/ZnS Quantum Dot Micelles for Cancer Cell Imaging
        Shanmugavel Chinnathambi
        10th Anniversary International Symposium on Nanomedicine (ISNM 2016), AIST, Tsukuba, Japan, Invited
      • Functionalized Quantum Dots for Biological Applications
        Shanmugavel Chinnathambi
        Advanced Materials Research Center (AMREC), Kulim, Malaysia,, Invited
      • Effect of interaction mode of CpG oligodeoxynucleotides with TLR9 on bifurcated cytokine induction
        Shanmugavel Chinnathambi
        The 6th Annual meeting of Nano-biomedical society, AIST, Tsukuba, Japan
      • Synthesis and characterization of positively charged silicon quantum dots for delivery of nucleic acid drugs
        Shanmugavel Chinnathambi
        The 6th Annual meeting of Nano-biomedical society, AIST, Tsukuba, Japan, Invited

      Books and Other Publications

      • Delivery of anticancer drugs and Behavior analysis of the drugs by Using optical character of the Carriers
        Shanmugavel Chinnathambi, Single work
        Aug. 2014

      Media Coverage

      • The quest for perfect quantum dot biomarkers
        Asia Research News, Jan. 2020, Paper
      • Biological imaging using near-infrared emission quantum dots
        Apr. 2019, Internet
      • Binding Mode of CpG Oligodeoxynucleotides to Nanoparticles Regulates Bifurcated Cytokine induction via Toll-like Receptor 9
        Nature Asia, Jul. 2012, Internet
      • Development of technology that enhances the efficacy of immunity-Activating nucleic acid drugs using nanoparticles –Application to treatment of allergic diseases and infectious diseases
        NIMS, Jun. 2012, Internet

      External funds: Kakenhi

      • Creation and biological evaluation of nanoparticle-based artificial transcription factor
        Grant-in-Aid for Early-Career Scientists
        Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
        Kyoto University
        CHINNATHAMBI Shanmugavel
        From 01 Apr. 2022, To 31 Mar. 2024, Granted
        NANO-TF;Silica nanoparticles;Mitochondrial factors

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