Basic Information

Email Address

• Email Address

  liu.chenchen.7hkyoto-u.ac.jp

Professional Memberships

• From Oct. 2022, To Present

  The Japan Society for Analytical Chemistry

Academic Degree

• 15 Jun. 2016

  上海理工大学博士（工学）
• 24 Sep. 2021

  京都大学博士（工学）

Academic Resume (Undergraduate School/Majors)

• 河南大学, 物理与電子学部物理学科, 卒業

Language of Instruction

• English
• Chinese
• Japanese

ID,URL

• ORCID ID

  0000-0001-9148-8029

• J-Global ID

  202201009713056802

• Researcher number

  50963211

researchmap URL

• https://researchmap.jp/lcc

Research

Research Areas

• Nanotechnology/Materials, Analytical chemistry, capillary electrophoresis, biomolecule detection, separation materials

Papers

• Single-cell N-glycan analysis via laser-induced fluorescent capillary electrophoresis with femtomolar sensitivity

  Chenchen Liu*; Nobuaki Matsumori; Takayuki Kawai*

  Sensors and Actuators B: Chemical, Jan. 2026, Peer-reviewed, Lead author, Corresponding author

  
• Online desalting of glycans labeled with 8-aminopyrene-1,3,6-trisulfonic acid via capillary electrophoresis

  Chenchen Liu*; Takayuki Kawai*

  Talanta, Jan. 2026, Lead author, Corresponding author

  
• Quantifying Cell Membrane Permeability of Small to Mid-Size Drugs Using Quick Osmotic Cytoplasm Extraction

  Serena Igari; Daiki Sakai; Chenchen Liu; Kohei Torikai; Nobuaki Matsumori; Takayuki Kawai*

  ANALYTICAL CHEMISTRY, 14 Oct. 2025

  
• Highly sensitive two-dimensional profiling of N-linked glycans by hydrophilic interaction liquid chromatography and dual stacking capillary gel electrophoresis.

  Takaya Miki; Sachio Yamamoto; Chenchen Liu; Kohei Torikai; Mitsuhiro Kinoshita; Nobuaki Matsumori; Takayuki Kawai*

  Analytica chimica acta, 01 Sep. 2024

  
• Recent advances in microscale separation techniques for glycome analysis (Top reviewed article in JSS (2024))

  Chenchen Liu*; Koji Otsuka; Takayuki Kawai*

  Journal of Separation Science, 11 Jun. 2024, Peer-reviewed, Invited, Lead author, Corresponding author

  
• Development of transient trapping micellar electrokinetic chromatography coupled with mass spectrometry for steroids analysis

  Yanawut Manmana; Chenchen Liu; Hiroshi Koino; Kenji Sueyoshi; Fumihiko Kitagawa; Takuya Kubo*; Koji Otsuka

  Chirality, 26 Jun. 2022, Peer-reviewed, Invited

  
• Specific recognition of a target protein, cytochrome c, using molecularly imprinted hydrogels

  Chenchen Liu; Takuya Kubo*; Koji Otsuka

  Journal of Materials Chemistry B, 2022, Lead author

  
• Fluorescent detection of target proteins via a molecularly imprinted hydrogel

  Takuya Kubo*; Naoki Watanabe; Seiji Ikari; Chenchen Liu; Eisuke Kanao; Toyohiro Naito; Tomoharu Sano; Koji Otsuka

  ANALYTICAL METHODS, Jul. 2021

  
• Hydrogels in Electrophoresis: Applications and Advances

  Chenchen Liu; Takuya Kubo*; Koji Otsuka

  ANALYTICAL SCIENCES, Jun. 2021, Lead author

  
• Controllable Molecular Sieving by copoly(Poly(ethylene glycol) Acrylate/Poly(ethylene glycol) Diacrylate)-Based Hydrogels via Capillary Electrophoresis for DNA Fragments

  Chenchen Liu; Takuya Kubo*; Toyohiro Naito; Koji Otsuka

  ACS Applied Polymer Materials, 11 Sep. 2020, Lead author

  
• Online fluorescence imaging method by reducing the inequivalent photobleaching for quantitative capillary electrophoresis

  Chenchen Liu; Yoshinori Yamaguchi*; Yi Wang; Xiaoming Dou; Takuya Kubo*; Koji Otsuka

  Sensors and Actuators B: Chemical, Sep. 2020, Lead author

  
• Rapid and quantitative detection of trace Sudan black B in dyed black rice by surface-enhanced Raman spectroscopy (SERS)

  Yubin Zhao; Yoshinori Yamaguchi*; Chenchen Liu; Mingda Li; Xiaoming Dou

  Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Jun. 2019

  
• Precise and simultaneous enumeration of multiplex pathogens using multiplex polymer chain reaction coupled with a novel quantitative capillary electrophoresis

  Chenchen Liu; Yoshinori Yamaguchi*; Shinichi Sekine; Yi Ni; Xiaoming Dou*

  Sensors and Actuators, B: Chemical, Apr. 2018, Lead author

  
• Quantitative Detection of Ethanol/Acetone in Complex Solutions Using Raman Spectroscopy Based on Headspace Gas Analysis

  Yubin Zhao; Yoshinori Yamaguchi*; Chenchen Liu; Shinichi Sekine; Xiaoming Dou

  APPLIED SPECTROSCOPY, Feb. 2018

  
• Analysis of Capillary Electrophoresis Noise Characteristics

  Gong Chen, Xifang Zhu, Xiaoming Dou, Chenchen Liu, Qingquan Xu, Yoshinori Yamaguchi, Yi Ni

  Guangzi Xuebao/Acta Photonica Sinica, Jun. 2017

  
• Molecular sieving polymer for DNA/RNA separation in capillary electrophoresis

  Chenchen Liu, Yoshinori Yamaguchi*, Xiaoming Dou

  International Journal of Modern Physics B, May 2017, Lead author

  
• Effective length calibration method for processing the fluorescence signal detected by charge-coupled device in capillary electrophoresis

  Yi Ni, Chenchen Liu, Jin Chen, Qinmiao Chen, Xifang Zhu, Xiaoming Dou*

  Journal of Separation Science, 02 Mar. 2017

  
• A Near Period-3 Feature Strategy to Improve the Extron Prediction

  Gong Chen, Chenchen Liu, Xifang Zhu, Yi Ni, Qingquan Xu, Xiaoming Dou

  Jiliang Xuebao/Acta Metrologica Sinica, 2017

  
• Rapid identification and quantitation for oral bacteria based on short-end capillary electrophoresis

  Jin Chen, Yi Ni*, Chenchen Liu, Yoshinori Yamaguchi, Qinmiao Chen, Shinichi Sekine, Xifang Zhu, Xiaoming Dou*

  Talanta, Nov. 2016

  
• Analysis of the inhibition of nucleic acid dyes on polymerase chain reaction by capillary electrophoresis

  Zhenqing Li*, Chenchen Liu, Siyao Ma, Dawei Zhang, Yoshinori Yamaguchi*

  Analytical Methods, Feb. 2016

  
• Capillary electrophoresis of RNA in hydroxyethylcellulose polymer with various molecular weights

  Zhenqing Li*, Chenchen Liu, Dawei Zhang, Shaopeng Luo, Yoshinori Yamaguchi*

  Journal of Chromatography B, Jan. 2016

  
• Gene analysis of multiple oral bacteria by the polymerase chain reaction coupled with capillary polymer electrophoresis

  Chenchen Liu; Yoshinori Yamaguchi*; Shinichi Sekine; Yi Ni; Zhenqing Li; Xifang Zhu; Xiaoming Dou*

  Journal of Separation Science, 2016, Lead author

  
• Theoretical investigation on the performance of DNA electrophoresis under programmed step electric field strength: Two-step condition

  Yi Ni, Chenchen Liu, Qinmiao Chen, Xifang Zhu, Xiaoming Dou*

  Journal of Separation Science, Oct. 2015

  
• Polyethylene Oxide (PEO) and Polyethylene Glycol (PEG) Polymer Sieving Matrix for RNA Capillary Electrophoresis

  Yoshinori Yamaguchi; Zhenqing Li*; Xifang Zhu; Chenchen Liu; Dawei Zhang; Xiaoming Dou*

  PLOS ONE, Jun. 2015

  
• Analysis of small interfering RNA by capillary electrophoresis in hydroxyethylcellulose solutions

  Chenchen Liu; Yoshinori Yamaguchi*; Xifang Zhu; Zhenqing Li; Yi Ni; Xiaoming Dou

  Electrophoresis, 13 Apr. 2015, Lead author

  
• Quantification of Periodontal Pathogens Cell Counts by Capillary Electrophoresis

  Zhenqing Li*, Shaoxiong Chen, Chenchen Liu, Dawei Zhang, Xiaoming Dou, Yoshinori Yamaguchi*

  Journal of Chromatography A, 07 Aug. 2014

  
• Electromigration behavior of nucleic acids in capillary electrophoresis under pulsed-field conditions

  Zhenqing Li*, Chenchen Liu, Xiaoming Dou*, Yi Ni, Jiaxuan Wang, Yoshinori Yamaguchi

  Journal of Chromatography A, 28 Mar. 2014

  
• Capillary electrophoresis of a wide range of DNA fragments in a mixed solution of hydroxyethyl cellulose

  Zhenqing Li*, Chenchen Liu, Yoshinori Yamaguchi, Yi Ni; Qingxiang You; Xiaoming Dou

  Analytical Methods, 09 Jan. 2014

  
• Capillary electrophoresis of DNA in hydroxyethylcellulose

  Chenchen Liu; Zhenqing Li*; Fanming Meng; Yi Ni; Xiaoming Dou; Yoshinori Yoshinori

  Acta Chimica Sinica, 2013, Lead author

  
• Effect of electric field modes on the separation performance of DNA in capillary electrophoresis

  Jin Chen, Zhenqing Li*, Yi Ni, Chenchen Liu, Xiaoming Dou, Yoshinori Yamaguchi

  Acta Chimica Sinica, 2012

  

Presentations

• Online Electrokinetic Desalting in Capillary Electrophoresis with High Recovery

  Liu Chenchen; Kawai Takayuki

  The International Chemical Congress of Pacific Basin Societies 2025, 15 Dec. 2025

  
• High Recovery Desalting of 8-Aminopyrene-1,3,6-trisulfonic Acid Labeled Glycans via Capillary Electrophoresis

  Chenchen Liu; Takayuki Kawai

  54th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC2025 Belgium), 16 Jun. 2025

  
• Online Salty Impurity Removal of 8-Aminopyrene-1,3,6-Trisulfonic Acid Labeled Glycans via Temporary Normal Polarity Capillary Electrophoresis

  Liu C.; Kawai T.

  41th International Symposium on Microscale Separation and Bioanalysis (MSB 2025), 19 May 2025

  
• Laser-Induced Fluorescence Detection of Femtomolar Aminopyrene Trisulfonic Acid-Labeled Glycans in Capillary Electrophoresis

  Liu C.; Kawai T.

  53rd International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2024), 22 Oct. 2024

  
• Toward 1000-fold Sensitivity Improvement of Capillary Electrophoresis coupled with Laser-Induced Fluorescence Detection for Aminopyrene Trisulfonic Acid Fluorophore

  Liu C.; Kawai T.

  40th International Symposium on Microscale Separation and Bioanalysis (MSB 2024), 19 May 2024

  
• What Factors Influence the Sensitivity of Capillary Electrophoresis-Laser Induced Fluorescence?

  Liu C.; Kawai T.

  43rd Capillary Electrophoresis Symposium (SCE2023), 30 Nov. 2023

  
• Accurate Quantitative Capillary Electrophoresis Unaffected by Inequitable Photobleaching-Induced Errors

  Liu C.; Yoshinori Y.; Kawai T.; Kubo T.; Otsuka K.

  19th Asia-Pacific International Symposium on Microscale Separations And Analysis 2023 (APCE 2023), 10 Oct. 2023, Invited

  
• Effect of Analytes’ Photobleaching in Quantitative Capillary Electrophoresis

  Liu C.; Yoshinori Y.; Kawai T.; Kubo T.; Otsuka K.

  30th Chromatography Symposium, 29 Jun. 2023

  
• Online Fluorescent Imaging Method for Accuracy Improvement of Quantitative Capillary Electrophoresis

  Liu C.; Yoshinori Y.; Kawai T.; Kubo T.; Otsuka K.

  51st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC2023), 19 Jun. 2023

  
• Online Fluorescent Imaging Method for Improving the Accuracy of Quantitative Capillary Electrophoresis

  Liu C.; Yoshinori Y.; Kawai T.; Kubo T.; Otsuka K.

  74th Academic Conference of the Japan Society of Electrophoresis, 20 May 2023

  
• New Studies on Poly(Ethylene Glycol)-Based Hydrogels in Electrophoresis

  Liu C.; Kubo T.; Kawai T.; Otsuka K.

  APCE-CECE-ITP-IUPAC 2022, 08 Nov. 2022

  
• Controllable Molecular Sieving Effect in Capillary Electrophoresis by Tuning The Network Structure of Poly (ethylene glycol)-Based Hydrogels

  Liu C.; Naito T.; Kubo T.; Otsuka K.

  International Chemical Congress of Pacific Basin Societies 2021 (Pacifichem 2021), 18 Dec. 2021

  
• Fabrication of Hydrogels for the Recognition of Specified Proteins via Grafting Molecularly Imprinted Polymers

  Liu C.; Kubo T.; Otsuka K.

  37th International Symposium on Microscale Separations and Bioanalysis (MSB2021), 12 Jul. 2021

  
• Evaluation of the Separation Efficiency Based on Molecular Sieving Effect Using the PEG-based Gel Capillary

  Liu C.; Toyohiro Naito; Takuya Kubo; Koji Otsuka

  30th Conference of the Society for Chromatographic Sciences (SCS30), 05 Dec. 2019

  
• Changeable Molecular Sieving Effect in Capillary Electrophoresis Using Poly(ethylene glycol) Based Hydrogels

  Liu C.; Naito T.; Kubo T.; Otsuka K.

  49th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC2019 Kyoto), 02 Dec. 2019

  
• Analysis of Small Interfering RNA by Capillary Polymer Electrophoresis in Hydroxyethylcellulose Solutions

  Liu C.; Dou X.; Zhu X.; Ni Y.; Yamaguchi Y.

  15th Asia-Pacific International Symposium on Microscale Separations and Analysis (APCE2015), 15 Nov. 2015