Basic Information

Academic Degree

• 博士（医学）(徳島大学)

Language of Instruction

• Japanese
• English

ID,URL

• ORCID ID

  0000-0002-0683-719X

• J-Global ID

  202001013256061814

researchmap URL

• https://researchmap.jp/KGMTSAK

Research

Papers

• 顔面の多発紅色局面

  入江 浩之; 内藤 惇; 小亀 敏明; 中溝 聡; 平田 勝啓; 藤本 正数; 椛島 健治

  日本皮膚病理組織学会抄録集, Jan. 2024

  
• Tinea corporis at the injection site of interleukin-17 inhibitor in psoriasis vulgaris

  Keigo Takase; Takayoshi Komatsu-Fujii; Toshiaki Kogame; Atsushi Otsuka; Kenji Kabashima

  British Journal of Dermatology, 26 Dec. 2024

  
• Presence of immunoglobulin E‐expressing antibody‐secreting cells in the dermis close to bullous pemphigoid lesions

  Fatimah Budair; Naotomo Kambe; Toshiaki Kogame; Masahiro Hirata; Riko Takimoto‐Ito; Alshimaa Mostafa; Takashi Nomura; Kenji Kabashima

  Experimental Dermatology, Apr. 2024

  
• A case of post herpes zoster granulomatous dermatitis successfully treated with UVA1 phototherapy

  Atsushi Naito; Toshiaki Kogame; Naotomo Kambe; Kenji Kabashima

  The Journal of Dermatology, Apr. 2024

  
• Lymphedema‐associated angiosarcoma uniquely localized on the left thigh and anterior abdominal wall secondary to central obesity and multiple surgeries

  Yui Hirano‐Lotman; Toshiaki Kogame; Yo Kaku; Takayoshi Komatsu‐Fujii; Yuichiro Endo; Takashi Nomura; Kenji Kabashima

  The Journal of Dermatology, Mar. 2024

  
• Exploring the role of Janus kinase (JAK) in atopic dermatitis: a review of molecular mechanisms and therapeutic strategies

  Toshiaki Kogame; Gyohei Egawa; Kenji Kabashima

  Immunological Medicine, 03 Jul. 2023

  Access this paper :

  
• A case of Kimura disease with atopic dermatitis successfully treated with baricitinib

  Marina Ueda; Toshiaki Kogame; Gyohei Egawa; Naotomo Kambe; Kenji Kabashima

  The Journal of Dermatology, Jun. 2023

  
• Galactosidase-catalyzed fluorescence amplification method (GAFAM): sensitive fluorescent immunohistochemistry using novel fluorogenic β-galactosidase substrates and its application in multiplex immunostaining

  Masahiro Hirata; Toshiaki Kogame; Souichi Adachi; Hironori Haga

  Histochemistry and Cell Biology, Mar. 2023

  
• At‐risk circumstances for COVID‐19 increase the risk of pruritus: cross‐sectional and longitudinal analyses

  T. Kogame; Y. Ogawa; K. Kabashima; Y. Yamamoto

  Journal of the European Academy of Dermatology and Venereology, Mar. 2022

  
• Case of multiple disseminated cutaneous lobular capillary hemangioma that developed while taking oral contraceptive pills

  Shunya Usui; Toshiaki Kogame; Mami Shibuya; Natsuko Okamoto; Eiko Toichi

  The Journal of Dermatology, Jun. 2019

  
• Case of multiple disseminated cutaneous lobular capillary hemangioma that developed while taking oral contraceptive pills

  Toshiaki Kogame

  The Journal of dermatology, 2019

  
• Convulsive seizure and pulmonary edema during hyperbaric oxygen therapy:A case report

  Toshiaki Kogame

  The journal of medical investigation : JMI, 2018

  
• Differential and common DNA repair pathways for topoisomerase I- and II-targeted drugs in a genetic DT40 repair cell screen panel

  Toshiaki Kogame

  Molecular cancer therapeutics, 2014

  
• Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1

  Toshiaki Kogame

  The Journal of biological chemistry, 2010

  
• GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination

  Toshiaki Kogame

  Nucleic acids research, 2010

  
• Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair

  Toshiaki Kogame

  PLoS genetics, 2010

  
• A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants

  Toshiaki Kogame

  Environmental health perspectives, 2009

  
• Ebselen attenuates oxidative stress-induced apoptosis via the inhibition of the c-Jun N-terminal kinase and activator protein-1 signalling pathway in PC12 cells

  Toshiaki Kogame

  British journal of pharmacology, 2002

  
• Summary of the current status of clinically diagnosed cases of Schnitzler syndrome in Japan

  Riko Takimoto-Ito; Naotomo Kambe; Toshiaki Kogame; Takashi Nomura; Kazushi Izawa; Tomoyasu Jo; Yasuhiro Kazuma; Hajime Yoshifuji; Yuya Tabuchi; Hiroyasu Abe; Mayuko Yamamoto; Kimiko Nakajima; Ozumi Tomita; Yosuke Yagi; Kazumoto Katagiri; Yuki Matsuzaka; Yohei Takeuchi; Miho Hatanaka; Takuro Kanekura; Sora Takeuchi; Takafumi Kadono; Yuya Fujita; Kiyoshi Migita; Takahiro Fujino; Takahiko Akagi; Tomoyuki Mukai; Tohru Nagano; Mitsuhiro Kawano; Hayato Kimura; Yukari Okubo; Akimichi Morita; Michihiro Hide; Takahiro Satoh; Akihiko Asahina; Nobuo Kanazawa; Kenji Kabashima

  Allergology International, Apr. 2023, Peer-reviewed

  Access this paper :

  
• Association of occupational direct radiation exposure to the hands with longitudinal melanonychia and hand eczema in spine surgeons: a survey by the society for minimally invasive spinal treatment (MIST).

  Yasukazu Hijikata; Tsukasa Kamitani; Yosuke Yamamoto; Takahiro Itaya; Toshiaki Kogame; Haruki Funao; Masayuki Miyagi; Tadatsugu Morimoto; Haruo Kanno; Akinobu Suzuki; Yoshihisa Kotani; Ken Ishii

  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, Dec. 2021

  
• Temporal triangular alopecia confined to the frontal scalp

  Jumpei Tahara; Teruki Dainichi; Yo Kaku; Tatsuki Kataoka; Hideaki Kishimoto; Toshiaki Kogame; Kenji Kabashima

  The Journal of Dermatology, Apr. 2021

  
• 円形脱毛症の病理学的分類によるT細胞のPD-1発現の解析

  千田 晃嘉; 野村 尚史; 小亀 敏明; 中溝 聡; 米倉 慧; 神戸 直智; 吉川 義顕; 椛島 健治

  日本皮膚免疫アレルギー学会総会学術大会プログラム・抄録集, Dec. 2022

  
• コレクチムODTが無効であった円形脱毛症の1例

  千田 晃嘉; 小亀 敏明; 椛島 健治

  皮膚の科学, Dec. 2021

  
• 1373 Expression of programmed cell death 1 inversely correlated with the density of CD8+ T cells infiltrating hair follicles in alopecia areata

  A. Senda; T. Nomura; S. Yonekura; T. Kogame; S. Nakamizo; K. Kabashima

  Journal of Investigative Dermatology, May 2023

  
• Necrotizing fasciitis with slow progression in a patient with rheumatoid arthritis receiving tocilizumab.

  Kazuya Goto; Toshiaki Kogame; Nobuhiro Kusuba; Yuichiro Endo; Teruki Dainichi; Kenji Kabashima

  European journal of dermatology : EJD, 01 Apr. 2022

  
• Increased type I interferon expression from T cells in lesional skin of Degos disease.

  Yuki Honda Keith; Atsushi Otsuka; Toshiaki Kogame; Hiroyuki Ito; Shunya Usui; Masakazu Fujimoto; Keita Jinnouchi; Masahiro Hirata; Kazumitsu Sugiura; Kenji Kabashima

  The Journal of dermatology, 27 Jan. 2023

  
• Refractory serum immunoglobulin M elevation during anti-interleukin (IL)-1- or IL-6-targeted treatment in four patients with Schnitzler syndrome.

  Riko Takimoto-Ito; Naotomo Kambe; Toshiaki Kogame; Atsushi Otsuka; Takashi Nomura; Kazushi Izawa; Yuya Tabuchi; Hajime Yoshifuji; Yohei Takeuchi; Kenji Kabashima

  The Journal of dermatology, Nov. 2021

  
• Interleukin-13 inhibition by tralokinumab reduces inducible T-cell costimulator-positive innate lymphoid cells in skin lesions of atopic dermatitis.

  Toshiaki Kogame; Satoru Yonekura; Paola Lovato; Masahiro Hirata; Riko Takimoto-Ito; Tomoya Takegami; Takayoshi Komatsu-Fujii; Naotomo Kambe; Takashi Nomura; Mads A Røpke; Kenji Kabashima

  The British journal of dermatology, 23 Jan. 2023

  
• 円形脱毛症の病理学的分類によるT細胞のPD-1発現の解析

  千田 晃嘉; 野村 尚史; 小亀 敏明; 中溝 聡; 米倉 慧; 神戸 直智; 吉川 義顕; 椛島 健治

  日本皮膚免疫アレルギー学会総会学術大会プログラム・抄録集, Dec. 2022

  
• Longitudinal association between polypharmacy and development of pruritus: a Nationwide Cohort Study in a Japanese Population

  T. Kogame; T. Kamitani; H. Yamazaki; Y. Ogawa; S. Fukuhara; K. Kabashima; Y. Yamamoto

  Journal of the European Academy of Dermatology and Venereology, Oct. 2021

  
• Treatment With Topical Sirolimus for Recurrent Lymphatic Malformation of the External Urethral Meatus.

  Satoru Yonekura; Takaya Komori; Yoshihiro Ishida; Toshiaki Kogame; Kenji Kabashima

  JAMA dermatology, 31 Aug. 2022

  
• 抗IL-13抗体製剤トラロキヌマブはアトピー性皮膚炎皮膚のヒト自然リンパ球を減少させる

  小亀 敏明; 米倉 慧; Lovato Paola; Ropke Mads A.; 椛島 健治

  日本皮膚科学会雑誌, May 2022

  
• 外尿道口リンパ管腫にラパリムスゲルが著効した1例

  米倉 慧; 小森 崇矢; 小亀 敏明; 椛島 健治

  皮膚の科学, Mar. 2022

  
• Immunohistochemical study of annular erythema appearing in a patient with sub‐acute cutaneous lupus erythematosus

  Kaori Shima; Takashi Nomura; Satoru Yonekura; Yuki Honda Keith; Toshiaki Kogame; Kosaku Murakami; Kenji Kabashima

  Skin Health and Disease, 15 Jun. 2022

  
• CCL2‒CCR2 Signaling in the Skin Drives Surfactant-Induced Irritant Contact Dermatitis through IL-1β‒Mediated Neutrophil Accumulation

  Rintaro Shibuya; Yoshihiro Ishida; Sho Hanakawa; Tatsuki R. Kataoka; Yasuhide Takeuchi; Teruasa Murata; Arisa Akagi; Zachary Chow; Toshiaki Kogame; Satoshi Nakamizo; Saeko Nakajima; Gyohei Egawa; Takashi Nomura; Naotomo Kambe; Akihiko Kitoh; Kenji Kabashima

  Journal of Investigative Dermatology, 2021

  
• 皮膚粘膜移行部に緊満性水疱を生じた抗ラミニンγ1類天疱瘡の1例

  小亀 敏明; 錦織 恵美; 笹橋 真紀子; 松井 美萌; 石井 文人; 大日 輝記

  皮膚の科学, Apr. 2019

  
• クリップ式ウィッグによって生じた牽引性脱毛症にsyringomatous metaplasiaを合併した1例

  小亀 敏明; 加来 洋; 大日 輝記; 椛島 健治

  皮膚の科学, Dec. 2017

  
• 帯状疱疹後に発症したerosive pustular dermatosis of the scalpの1例

  後藤 和哉; 野村 尚史; 小亀 敏明; 加来 洋; 大日 輝記; 田邉 洋; 椛島 健治

  Journal of Environmental Dermatology and Cutaneous Allergology, Nov. 2017

  
• Giant Pilomatrical Tumor With Broad Epidermal Components: An Example of Histological Diversity and a Potential Diagnostic Pitfall of Tumors With Pilomatrical Differentiation.

  Kazuhiro Terada; Yosuke Yamada; Masakazu Fujimoto; Shunya Usui; Toshiaki Kogame; Yo Kaku; Koki Moriyoshi; Hironori Haga

  The American Journal of dermatopathology, 20 Jul. 2021

  
• Skin‐associated lymphoid tissue could be a sign of systemic disease: reply from authors

  T. Kogame; N. Kambe; R. Takimoto‐Ito; T. Nomura; K. Kabashima

  British Journal of Dermatology, Jul. 2021, Peer-reviewed, Lead author

  
• Inducible skin-associated lymphoid tissue (iSALT) in a patient with Schnitzler syndrome who manifested wheals on recurrent localized erythema.

  H Kamido; D Shimomiya; T Kogame; R Takimoto-Ito; T R Kataoka; M Hirata; C Ueshima; A Otsuka; F M Ghazawi; T Nomura; N Kambe; K Kabashima

  The British journal of dermatology, 14 Jan. 2021, Peer-reviewed, Corresponding author

  
• Immunohistochemical analysis of class‐switched subtype of primary cutaneous marginal zone lymphoma in terms of inducible skin‐associated lymphoid tissue

  T. Kogame; T. Takegami; T.R. Sakai; T.R. Kataoka; M. Hirata; F.M. Budair; C. Ueshima; M. Matsui; T. Nomura; K. Kabashima

  Journal of the European Academy of Dermatology and Venereology, Nov. 2019, Peer-reviewed, Lead author

  
• Presence of SCF/CXCL12 double-positive large blast-like cells at the site of cutaneous extramedullary haematopoiesis

  Toshiaki Kogame

  Journal of the European Academy of Dermatology and Venereology : JEADV, Dec. 2018, Peer-reviewed, Lead author

  
• Analysis of possible structures of inducible skin‐associated lymphoid tissue in lupus erythematosus profundus

  Toshiaki Kogame; Ryosuke Yamashita; Masahiro Hirata; Tatsuki R. Kataoka; Hisashi Kamido; Chiyuki Ueshima; Miho Matsui; Takashi Nomura; Kenji Kabashima

  The Journal of Dermatology, Sep. 2018, Peer-reviewed, Lead author

  
• A follow-up report of acral melanoma in a patient with Nagashima-type palmoplantar keratosis: validation of SERPINB7 mutation and local recurrence

  Toshiaki Kogame; Yo Kaku; Yuichiro Endo; Chisato Yamashita; Ayumi Horiguchi; Akiharu Kubo; Kenji Kabashima

  European Journal of Dermatology, Jul. 2018, Peer-reviewed, Lead author

  
• Extraocular sebaceous carcinoma accompanied by invasive squamous cell carcinoma: The first case report and consideration of histogenesis

  Toshiaki Kogame; Shuichi Ohe; Fumikazu Yamazaki; Hiroyuki Okamoto; Takahiro Kiyohara

  Journal of Dermatology, 01 Apr. 2018, Peer-reviewed, Lead author

  
• 手掌に悪性黒色腫を発症した長島型掌蹠角化症の1例

  小亀 敏明; 加来 洋; 遠藤 雄一郎; 山下 千聡; 堀口 亜有未; 岩田 昌史; 椛島 健治

  角化症研究会記録集, Mar. 2018, Peer-reviewed

  
• 盲腸癌に対する抗癌剤治療中に好酸球性膿疱性毛包炎を合併した1例

  八代 敦子; 野村 尚史; 入江 浩之; 加来 洋; 遠藤 雄一郎; 中島 沙恵子; 椛島 健治; 小亀 敏明

  皮膚の科学, Dec. 2017, Peer-reviewed

  
• Solar urticaria with an augmentation spectrum in a child.

  Toshiaki Kogame; Naoko Uetsu; Chuyen Thi Hong Nguyen; Akira Kawada; Hiroyuki Okamoto

  The Journal of dermatology, Sep. 2017, Peer-reviewed, Lead author

  
• Spindle cell squamous cell carcinoma arising in Bowen's disease: Case report and review of the published work

  Toshiaki Kogame; Hirotsugu Tanimura; Sei Nakamaru; Kaoru Makimura; Hiroyuki Okamoto; Takahiro Kiyohara

  JOURNAL OF DERMATOLOGY, Sep. 2017, Peer-reviewed

  
• Possible inducible skin-associated lymphoid tissue (iSALT)-like structures with CXCL13+ fibroblast-like cells in secondary syphilis

  T. Kogame; T. Nomura; T. Kataoka; M. Hirata; C. Ueshima; M. Matsui; K. Kabashima

  British Journal of Dermatology, 2017, Peer-reviewed, Lead author

  
• 猫咬傷から壊死性筋膜炎を生じた1例

  菊池 綾子; 要石 就斗; 小亀 敏明; 遠藤 雄一郎; 大日 輝記; 椛島 健治; 山下 彩; 松井 美萌

  皮膚の科学, Aug. 2016, Peer-reviewed

  
• 【筋膜・皮下組織の疾患】臨床例 蜂窩織炎を契機に判明した非結核性抗酸菌性腱鞘炎

  入江 浩之; 藤澤 章弘; 小亀 敏明; 仲野 祐里; 遠藤 雄一郎; 大日 輝記; 椛島 健治

  皮膚病診療, Jan. 2016, Peer-reviewed

  
• 4-Fragment Gateway cloning format for MosSCI-compatible vectors integrating Promoterome and 3’UTRome libraries of Caenorhabditis elegans

  Toshiaki Kogame

  Journal of Medical Investigation, 18 Sep. 2015, Peer-reviewed, Lead author, Last author, Corresponding author

  
• 蜂窩織炎を契機に判明した非結核性抗酸菌膿瘍の1例

  入江 浩之; 劉 祐里; 遠藤 雄一郎; 藤澤 章弘; 谷岡 未樹; 大日 輝記; 椛島 健治; 宮地 良樹; 野口 貴志; 太田 壮一; 小亀 敏明

  皮膚の科学, Dec. 2014, Peer-reviewed

  
• Palmoplantar keratosis in oculodentodigital dysplasia with a GJA1 point mutation out of the C-terminal region of connexin 43

  Toshiaki Kogame; Teruki Dainichi; Yutaka Shimomura; Miki Tanioka; Kenji Kabashima; Yoshiki Miyachi

  Journal of Dermatology, 01 Dec. 2014, Peer-reviewed

  

Misc.

• Putative Immunological Functions of Inducible Skin-Associated Lymphoid Tissue in the Context of Mucosa-Associated Lymphoid Tissue

  Toshiaki Kogame; Kenji Kabashima; Gyohei Egawa

  Frontiers in Immunology, 26 Aug. 2021

  
• Acquired idiopathic generalized anhidrosis following pembrolizumab treatment

  K. Furuta; A. Horiguchi; Y. Nakagawa; N. Kambe; T. Kogame

  Clinical and Experimental Dermatology, 2021

  
• An Infantile Hemangioma Showing an A trophic Plaque in the Middle of the Lower Back

  小亀 敏明; 藤澤 章弘; 加来 洋; 宮地 良樹; 椛島 健治

  皮膚科の臨床, Mar. 2017

  
• Improvement of erosive pustular dermatosis of the scalp following discontinuation of chemotherapy with afatinib

  Kazuya Goto; Takashi Nomura; Toshiaki Kogame; Hiroyuki Irie; Yo Kaku; Teruki Dainichi; Kenji Kabashima

  European Journal of Dermatology, 01 Mar. 2018

  
• The lymphokine signatures of angiomatoid fibrous histiocytoma revealed by immunohistochemistry

  T. Nomura; K. Kabashima; R. Yamashita; T. Kogame

  JOURNAL OF INVESTIGATIVE DERMATOLOGY, Oct. 2017

  
• Presence of inducible skin-associated lymphoid tissue (iSALT)-like structures with CXCL13+fibroblast-like cells in secondary syphilis

  T. Nomura; T. Kogame; K. Kabashima

  JOURNAL OF INVESTIGATIVE DERMATOLOGY, May 2017

  
• Analysis of lymphoid tissue markers in angiomatoid fibrous histiocytoma

  Takashi Nomura; Toshiaki Kogame; Kenji Kabashima

  JOURNAL OF IMMUNOLOGY, May 2017

  
• A possible role of SCF for the formation of stem cell niche in extramedullary hematopoiesis in the skin

  T. Kogame; T. Nomura; K. Kabashima

  JOURNAL OF INVESTIGATIVE DERMATOLOGY, May 2017, Lead author

  
• Maculopapular rash during a nadir period in a patient with acute myeloid leukaemia

  Takaya Komori; Toshiaki Kogame; Takashi Nomura; Yo Kaku; Yuichiro Endo; Chiyuki Ueshima; Masahiro Hirata; Tatsuki R. Kataoka; Hiroshi Kawabata; Kenji Kabashima

  EUROPEAN JOURNAL OF DERMATOLOGY, May 2017

  
• SUBSEQUENT SKIN LESIONS CHARACTERISTIC TO PSORIASIS PUSTULOSA IN A ULCERATIVE COLITIS AND CUTANEOUS MANIFESTATIONS OF ARTHROPATHIC PSORIASIS IN CROHN DISEASE AFTER INFLIXIMAB TREATMENT

  Toshiaki Kogame; Fumikazu Yamazaki; Hirotsugu Tanimura; Kana Mizuno; Takahiro Kiyohara; Hiroyuki Okamoto

  JOURNAL OF DERMATOLOGY, Oct. 2014

  

External funds: Kakenhi

• Investigation of lymphoid follicle structures in the skin as ectopic lymphoid tissues, iSALT

  Grant-in-Aid for Early-Career Scientists

  Basic Section 53050:Dermatology-related

  Kyoto University

  小亀 敏明

  From 01 Apr. 2021, To 31 Mar. 2024, Granted

  iSALT;MALT;皮膚局所免疫;三次リンパ濾胞;三次リンパ濾胞様構造;三次リンパ組織;局所免疫;皮膚

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K16227/
• 皮膚局所のリンパネットワークとしてのiSALTについての検討

  Grant-in-Aid for Early-Career Scientists

  Basic Section 53050:Dermatology-related

  Kyoto University

  小亀 敏明

  From 01 Apr. 2023, To 31 Mar. 2025, Granted

  皮膚局所免疫;iSALT;三次リンパ濾胞;MALT

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K15284/
• Innovations in clinical epidemiology through spatial epidemiological analysis of images and pathological specimens

  Grant-in-Aid for Challenging Research (Pioneering)

  Medium-sized Section 58:Society medicine, nursing, and related fields

  Kyoto University

  山本 洋介

  From 28 Jun. 2024, To 31 Mar. 2029, Granted

  臨床疫学;空間疫学;QOL;免疫組織化学染色標本;画像解析

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K21305/
• Innovations in clinical epidemiology through spatial epidemiological analysis of images and pathological specimens

  Grant-in-Aid for Challenging Research (Pioneering)

  Medium-sized Section 58:Society medicine, nursing, and related fields

  Kyoto University

  山本 洋介

  From 28 Jun. 2024, To 31 Mar. 2029, Granted

  臨床疫学;空間疫学;QOL;免疫組織化学染色標本;画像解析

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K21305/