Search for faculty members
Hattori, Ayuna
Institute for Life and Medical Sciences (LiMe) Associate Professor
list
Last Updated :2025/05/27
Basic Information
Affiliated programs (koza)
- Graduate School of Pharmaceutical Sciences, 薬科学専攻 がん・幹細胞シグナル学, 准教授
- Graduate School of Medicine, 医学専攻 がん・幹細胞シグナル, 准教授
- Graduate School of Medicine, 医科学専攻がん・幹細胞シグナル, 准教授
Academic Degree
ID,URL
ORCID ID
J-Global ID
researchmap URL
list
Last Updated :2025/05/27
Research
Research Areas
Papers
- 分岐鎖アミノ酸代謝を介した正常組織幹細胞とがん幹細胞維持機構服部鮎奈; 慶澤遥; 伊藤貴浩生体の科学, Oct. 2023, Invited, Lead author
- The RNA-binding protein Msi2 regulates autophagy during myogenic differentiation.Ruochong Wang; Futaba Kato; Rio Yasui Watson; Aaron M Beedle; Jarrod A Call; Yugo Tsunoda; Takeshi Noda; Takaho Tsuchiya; Makoto Kashima; Ayuna Hattori; Takahiro ItoLife science alliance, May 2024, Peer-reviewed
- Genetic and chemical targeting of the ATPase complex TIP48 and 49 impairs acute myeloid leukemiaAyuna Hattori; Emi Takamatsu-Ichihara; Yoshiki Yamamoto; Shuhei Fujita; Kazutsune Yamagata; Takuo Katsumoto; Yukino Machida; Haruka Shinohara; Ryo Murakami; Issay KitabayashiLeukemia, 25 Jul. 2023, Peer-reviewed, Lead author, Corresponding author
- Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors.Haruka Shinohara; Rie Sawado; Makoto Nakagawa; Ayuna Hattori; Kazutsune Yamagata; Kimiharu Tauchi; Jumpei Ito; Yasumichi Kuwahara; Tsukasa Okuda; Chitose Ogawa; Issay KitabayashiMolecular therapy oncolytics, 15 Dec. 2022, Peer-reviewed
- Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia.Koji Jimbo; Ayuna Hattori; Shuhei Koide; Takahiro Ito; Katsuhiro Sasaki; Kazuhiro Iwai; Yasuhito Nannya; Atsushi Iwama; Arinobu Tojo; Takaaki KonumaLeukemia, 09 Nov. 2022, Peer-reviewed
- Clinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcomaMakoto Nakagawa; Masayuki Yamaguchi; Makoto Endo; Yukino Machida; Ayuna Hattori; Fumie Tanzawa; Shinji Tsutsumi; Issay Kitabayashi; Akira Kawai; Fumihiko NakataniJournal of Bone Oncology, Jun. 2022, Peer-reviewed
- 代謝からみえる幹細胞の機能制御と造血器腫瘍山本佳輝; 服部鮎奈; 伊藤貴浩血液内科, May 2022
- Determination of intracellular 2-hydroxyglutarate enantiomers using two-dimensional liquid chromatographyTakuma Ohtawa; Ayuna Hattori; Muneki Isokawa; Masashi Harada; Takashi Funatsu; Takahiro Ito; Makoto TsunodaJournal of Chromatography Open, Nov. 2021, Peer-reviewed
- がん組織における分岐鎖アミノ酸代謝制御服部 鮎奈May 2020, Lead author
- Amino acid metabolism for cancer therapy.服部 鮎奈Apr. 2020, Lead author
- BCAA代謝のリプログラミングによるがん幹細胞維持の機構服部 鮎奈; 伊藤 貴浩Jun. 2018, Lead author
- Analysis of intracellular alpha-keto acids by HPLC with fluorescence detectionTakuya Fujiwara; Ayuna Hattori; Takahiro Ito; Takashi Funatsu; Makoto TsunodaANALYTICAL METHODS, May 2020, Peer-reviewed
- A Potent Blood–Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft ModelYukino Machida; Makoto Nakagawa; Hironori Matsunaga; Masayuki Yamaguchi; Yoko Ogawara; Yutaka Shima; Kazutsune Yamagata; Takuo Katsumoto; Ayuna Hattori; Masato Itoh; Takahiko Seki; Yumi Nishiya; Koichi Nakamura; Kanae Suzuki; Tomoki Imaoka; Daichi Baba; Makoto Suzuki; Oltea Sampetrean; Hideyuki Saya; Koichi Ichimura; Issay KitabayashiMolecular Cancer Therapeutics, Feb. 2020, Peer-reviewed
- Selective inhibition of mutant IDH1 by DS-1001b ameliorates aberrant histone modifications and impairs tumor activity in chondrosarcoma.Makoto Nakagawa; Fumihiko Nakatani; Hironori Matsunaga; Takahiko Seki; Makoto Endo; Yoko Ogawara; Yukino Machida; Takuo Katsumoto; Kazutsune Yamagata; Ayuna Hattori; Shuhei Fujita; Yukiko Aikawa; Takamasa Ishikawa; Tomoyoshi Soga; Akira Kawai; Hirokazu Chuman; Nobuhiko Yokoyama; Suguru Fukushima; Kenichiro Yahiro; Atsushi Kimura; Eijiro Shimada; Takeshi Hirose; Toshifumi Fujiwara; Nokitaka Setsu; Yoshihiro Matsumoto; Yukihide Iwamoto; Yasuharu Nakashima; Issay KitabayashiOncogene, Oct. 2019, Peer-reviewed
- Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma.Nakagawa M; Fujita S; Katsumoto T; Yamagata K; Ogawara Y; Hattori A; Kagiyama Y; Honma D; Araki K; Inoue T; Kato A; Inaki K; Wada C; Ono Y; Yamamoto M; Miura O; Nakashima Y; Kitabayashi ICancer science, Jan. 2019, Peer-reviewed
- Continuous in vivo Metabolism by NMR.Judge MT; Wu Y; Tayyari F; Hattori A; Glushka J; Ito T; Arnold J; Edison ASFrontiers in molecular biosciences, 2019, Peer-reviewed
- Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemiaAyuna Hattori; Makoto Tsunoda; Takaaki Konuma; Masayuki Kobayashi; Tamas Nagy; John Glushka; Fariba Tayyari; Daniel M. Cskimming; Natarajan Kannan; Arinobu Tojo; Arthur S. Edison; Takahiro ItoNATURE, May 2017, Peer-reviewed, Lead author
- RNA binding protein MSI2 positively regulates FLT3 expression in myeloid leukemiaAyuna Hattori; Daniel McSkimming; Natarajan Kannan; Takahiro ItoLEUKEMIA RESEARCH, Mar. 2017, Peer-reviewed, Lead author
- Analysis of Branched-Chain Keto Acids in Cell Extracts by HPLC-Fluorescence DetectionAyuna Hattori; Takahiro Ito; Makoto TsunodaCHROMATOGRAPHY, 2017, Peer-reviewed, Lead author
- Chaperone complex BAG2-HSC70 regulates localization of Caenorhabditis elegans leucine-rich repeat kinase LRK-1 to the GolgiTakashi Fukuzono; Strahil Iv. Pastuhov; Okinobu Fukushima; Chun Li; Ayuna Hattori; Shun-ichiro Iemura; Tohru Natsume; Hiroshi Shibuya; Hiroshi Hanafusa; Kunihiro Matsumoto; Naoki HisamotoGENES TO CELLS, Apr. 2016, Peer-reviewed
External funds: Kakenhi
- タンパク質切断による新しい幹細胞機能制御の解明Grant-in-Aid for Scientific Research (B)Basic Section 54010:Hematology and medical oncology-relatedKyoto University服部 鮎奈From 01 Apr. 2022, To 31 Mar. 2026, Grantedがん幹細胞;RNA結合因子
- Regulation of cancer stem cell by RNA binding proteinGrant-in-Aid for Early-Career ScientistsBasic Section 54010:Hematology and medical oncology-relatedKyoto University;National Cancer Center JapanAyuna HattoriFrom 01 Apr. 2020, To 31 Mar. 2023, Discontinuedがん幹細胞;細胞運命決定;白血病;転写後制御
- The possibility of cancer therapy targeting to cellular iron metabolismGrant-in-Aid for Scientific Research (C)Basic Section 47030:Pharmaceutical hygiene and biochemistry-relatedTokai UniversityMasaki MiyazawaFrom 01 Apr. 2020, To 31 Mar. 2023, Project Closedがん;鉄代謝;抗がん剤;シスプラチン;IRP2
- Understanding metabolic impacts by IDH mutations and validating the efficacy of therapeutic targeting of BCAT1Grant-in-Aid for Research Activity Start-up0904:Internal medicine of the bio-information integration and related fieldsNational Cancer Center JapanAyuna HattoriFrom 24 Aug. 2018, To 31 Mar. 2020, Project Closedがん代謝;白血病;アミノ酸;IDH
- 鉄代謝因子阻害薬による革新的がん治療法の開発Grant-in-Aid for Scientific Research (C)Basic Section 47030:Pharmaceutical hygiene and biochemistry-relatedTokai University宮沢 正樹From 01 Apr. 2023, To 31 Mar. 2026, Granted鉄代謝;がん;IRP;IRE;創薬
- タンパク質切断による新しい幹細胞機能制御の解明Grant-in-Aid for Scientific Research (B)Basic Section 54010:Hematology and medical oncology-relatedKyoto University服部 鮎奈From 01 Apr. 2022, To 31 Mar. 2026, Grantedがん幹細胞;RNA結合因子
- 腸内糖鎖資化性細菌由来低分子代謝物による他臓器、腫瘍幹細胞の機能制御解明Grant-in-Aid for Transformative Research Areas (B)Transformative Research Areas, Section (III)Kyoto University服部 鮎奈From 01 Apr. 2025, To 31 Mar. 2028, Adopted
External funds: others
list
Last Updated :2025/05/27
Education
Teaching subject(s)
- From 01 Apr. 2024, To 31 Mar. 2025Research Proposal Writing Practice B8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2024, To 31 Mar. 2025Research Proposal Writing Practice A8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2024, To 31 Mar. 2025Pharmaceutical Laboratory Coaching Practice A8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2024, To 31 Mar. 2025Medicinal Frontier Science Research B8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2024, To 31 Mar. 2025Medicinal Frontier Science Research A8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2024, To 31 Mar. 2025Pharmaceutical Laboratory IV : Biochemistry and MicrobiologyC906, Fall, Faculty of Pharmaceutical Sciences, 3
- From 01 Apr. 2024, To 31 Mar. 2025Medicinal Frontier Science Research C8408, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2024, To 31 Mar. 2025Seminar on Critical Reading of Scientific Papers B8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2024, To 31 Mar. 2025Seminar on Critical Reading of Scientific Papers A8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Research Proposal Writing Practice A8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2023, To 31 Mar. 2024Pharmaceutical Laboratory Coaching Practice A8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2023, To 31 Mar. 2024Research Proposal Writing Practice B8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2023, To 31 Mar. 2024Pharmaceutical Laboratory IV : Biochemistry and MicrobiologyC906, Fall, Faculty of Pharmaceutical Sciences, 3
- From 01 Apr. 2023, To 31 Mar. 2024Medicinal Frontier Science Research B8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2023, To 31 Mar. 2024Medicinal Frontier Science Research A8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2023, To 31 Mar. 2024Pharmaceutical Laboratory 4 : Biochemistry and MicrobiologyA906, Fall, Faculty of Pharmaceutical Sciences, 4
- From 01 Apr. 2023, To 31 Mar. 2024Seminar on Critical Reading of Scientific Papers B8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2023, To 31 Mar. 2024Seminar on Critical Reading of Scientific Papers A8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Medical Frontier Science Research A8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
- From 01 Apr. 2022, To 31 Mar. 2023ILAS SeminarZ001, Spring, Institute for Liberal Arts and Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Pharmaceutical Laboratory 4 : Biochemistry and MicrobiologyA906, Fall, Faculty of Pharmaceutical Sciences, 4
- From 01 Apr. 2022, To 31 Mar. 2023Seminar on Critical Reading of Scientific Papers A8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
- From 01 Apr. 2022, To 31 Mar. 2023Pharmaceutical Laboratory IV : Biochemistry and MicrobiologyC906, Fall, Faculty of Pharmaceutical Sciences, 3
- From 01 Apr. 2022, To 31 Mar. 2023Pharmaceutical Laboratory Coaching Practice A8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
- From 01 Apr. 2022, To 31 Mar. 2023Research Proposal Writing Practice A8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
