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Hoshino, Masaru

Graduate School of Pharmaceutical Sciences, Division of Pharmaceutical Sciences Associate Professor

Hoshino, Masaru
list
    Last Updated :2026/10/20

    Basic Information

    Faculty

    • 薬学部

    Professional Memberships

    • From Apr. 1993, To Present
      日本生物物理学会
    • From Apr. 1994, To Mar. 2021
      日本生化学会
    • 米国Protein Sosiety

    Academic Degree

    • 修士(理学)(大阪大学)
    • 博士(理学)(大阪大学)

    Academic Resume (Graduate Schools)

    • 大阪大学, 大学院理学研究科博士前期課程(生物化学専攻), 修了
    • 大阪大学, 大学院理学研究科博士後期課程(生物化学専攻), 修了

    Academic Resume (Undergraduate School/Majors)

    • 大阪大学, 理学部生物学科, 卒業

    Research History

    • From Apr. 2007, To Present
      Kyoto University, Graduate School of Pharmaceutical Sciences, Associate Professor
    • From Apr. 2004, To Mar. 2007
      Kyoto University, Graduate School of Pharmaceutical Sciences, Associate Professor
    • From 1998, To 2004
      Osaka University, Institute for Protein Research, Research Assistant

    Language of Instruction

    • English
    • Japanese

    ID,URL

    researchmap URL

    list
      Last Updated :2026/10/20

      Research

      Research Topics, Overview of the research

      • Research Topics

        Structural analysis of intrinsically disordered proteins by high resolution NMR.
      • Overview of the research

        タンパク質は一般に、それ自身のアミノ酸配列に応じた立体構造を形成することにより、様々な生理的機能を発現する。近年、生理的条件下において特定の立体構造をもたない「天然変性タンパク質」と呼ばれるタンパク質が数多く存在することが明らかとなってきた。結晶化が困難なこれらのタンパク質の構造・ダイナミクスを、高分解能NMR分光法を用いて詳細に解析する。

      Research Interests

      • 構造生物化学
      • 生物物理学
      • Biophysics

      Research Areas

      • Life sciences, Biophysics
      • Life sciences, Structural biochemistry

      Papers

      • Balance between Association and Dissociation Rate Constants Determines Morphology and Property of Amyloid Fibrils
        Taiga Nakagawa; Daisuke Tsuri; Ichiro Nishii; Naoko Kajimura; Katsumi Matsuzaki; Masaru Hoshino
        The Journal of Physical Chemistry B, 29 Nov. 2024
      • Structural and thermodynamical insights into the binding and inhibition of FIH-1 by the N-terminal disordered region of Mint3
        Tensho Ten; Satoru Nagatoishi; Ryo Maeda; Masaru Hoshino; Yoshiaki Nakayama; Motoharu Seiki; Takeharu Sakamoto; Kouhei Tsumoto
        Journal of Biological Chemistry, Oct. 2021, Peer-reviewed
      • Letter to the Editor: A still unresolved mystery in the interaction between intrinsically disordered proteins: How do they recognize multiple target proteins?
        Masaru Hoshino
        Biophysics and Physicobiology, 2020, Invited, Lead author, Corresponding author
      • A novel mode of interaction between intrinsically disordered proteins
        Emi Hibino; Masaru Hoshino
        Biophysics and Physicobiology, 2020, Peer-reviewed, Corresponding author
      • Structural characterization of the N-terminal kinase-interacting domain of an Hsp90-cochaperone Cdc37 by CD and solution NMR spectroscopy
        Futoshi Ihama; Mami Yamamoto; Chojiro Kojima; Toshimichi Fujiwara; Katsumi Matsuzaki; Yoshihiko Miyata; Masaru Hoshino
        Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Sep. 2019, Peer-reviewed, Corresponding author
      • Novel Interaction Mechanism between the Intrinsically Disordered Proteins
        Emi HIBINO; Masaru HOSHINO
        Seibutsu Butsuri, 2019
      • Toxic Amyloid Tape: A Novel Mixed Antiparallel/Parallel β-Sheet Structure Formed by Amyloid β-Protein on GM1 Clusters.
        Okada Y; Okubo K; Ikeda K; Yano Y; Hoshino M; Hayashi Y; Kiso Y; Itoh-Watanabe H; Naito A; Matsuzaki K
        ACS chemical neuroscience, Jan. 2019, Peer-reviewed
      • Use of a Compact Tripodal Tris(bipyridine) Ligand to Stabilize a Single-Metal-Centered Chirality: Stereoselective Coordination of Iron(II) and Ruthenium(II) on a Semirigid Hexapeptide Macrocycle
        Yuka Kobayashi; Masaru Hoshino; Tomoshi Kameda; Kazuya Kobayashi; Kenichi Akaji; Shinsuke Inuki; Hiroaki Ohno; Shinya Oishi
        Inorganic Chemistry, 07 May 2018, Peer-reviewed
      • Not Oligomers but Amyloids are Cytotoxic in the Membrane-Mediated Amyloidogenesis of Amyloid-β Peptides
        Naoya Itoh; Eri Takada; Kaori Okubo; Yoshiaki Yano; Masaru Hoshino; Akira Sasaki; Masataka Kinjo; Katsumi Matsuzaki
        ChemBioChem, 02 Mar. 2018, Peer-reviewed
      • Identification of heteromolecular binding sites in transcription factors Sp1 and TAF4 using high-resolution nuclear magnetic resonance spectroscopy
        Emi Hibino; Rintaro Inoue; Masaaki Sugiyama; Jun Kuwahara; Katsumi Matsuzaki; Masaru Hoshino
        PROTEIN SCIENCE, Nov. 2017, Peer-reviewed
      • Fe(II)-Complexation of tripodal hexapeptide ligands with three bidentate triazolylpyridines: induction of metal-centred chirality by peptide macrocyclization
        Yuka Kobayashi; Tomoshi Kameda; Masaru Hoshino; Nobutaka Fujii; Hiroaki Ohno; Shinya Oishi
        DALTON TRANSACTIONS, Oct. 2017, Peer-reviewed
      • Aromaticity of Phenylalanine Residues Is Essential for Amyloid Formation by Alzheimer's Amyloid beta-Peptide
        Mayumi Genji; Yoshiaki Yano; Masaru Hoshino; Katsumi Matsuzaki
        CHEMICAL & PHARMACEUTICAL BULLETIN, Jul. 2017, Peer-reviewed
      • Fibril formation from the amyloid-β peptide is governed by a dynamic equilibrium involving association and dissociation of the monomer
        Masaru Hoshino
        Biophysical Reviews, 01 Feb. 2017, Peer-reviewed
      • Interaction between intrinsically disordered regions in transcription factors Sp1 and TAF4
        Emi Hibino; Rintaro Inoue; Masaaki Sugiyama; Jun Kuwahara; Katsumi Matsuzaki; Masaru Hoshino
        PROTEIN SCIENCE, Nov. 2016, Peer-reviewed
      • Effects of C-terminal Truncation of Chaperonin GroEL on the Yield of In-cage Folding of the Green Fluorescent Protein
        So Ishino; Yasushi Kawata; Hideki Taguchi; Naoko Kajimura; Katsumi Matsuzaki; Masaru Hoshino
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jun. 2015, Peer-reviewed
      • The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates
        Daichi Morimoto; Erik Walinda; Harumi Fukada; Yu-Shin Sou; Shun Kageyama; Masaru Hoshino; Takashi Fujii; Hikaru Tsuchiya; Yasushi Saeki; Kyohei Arita; Mariko Ariyoshi; Hidehito Tochio; Kazuhiro Iwai; Keiichi Namba; Masaaki Komatsu; Keiji Tanaka; Masahiro Shirakawa
        Nature Communications, Jan. 2015, Peer-reviewed
      • Comparison between the Aggregation of Human and Rodent Amyloid beta-Proteins in GM1 Ganglioside Clusters
        Hiroshi Ueno; Takahiro Yamaguchi; Saori Fukunaga; Yuki Okada; Yoshiaki Yano; Masaru Hoshino; Katsumi Matsuzaki
        BIOCHEMISTRY, Dec. 2014, Peer-reviewed
      • Evaluation of the stability of an SR398/GroES chaperonin complex
        So Ishino; Yasushi Kawata; Takahisa Ikegami; Katsumi Matsuzaki; Masaru Hoshino
        JOURNAL OF BIOCHEMISTRY, May 2014, Peer-reviewed
      • 3SEA-05 The interaction between transcription factors Sp1 and TAF4 via the intrinsically disordered regions(Frontiers in physical properties of proteins: challenges by young scientists,Symposium,The 52th Annual Meeting of the Biophysical Society of Japan(BSJ2014))
        Hibino Emi; Inoue Rintaro; Sugiyama Masaaki; Kuwahara Jun; Matsuzaki Katsumi; Hoshino Masaru
        Seibutsu Butsuri, 2014
      • 1P075 Effect of C-terminal truncation of chaperonin GroEL on the yield of an in-cage folding of GFP(01D. Protein : Function,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))
        Ishino So; Kawata Yasushi; Taguchi Hideki; Matsuzaki Katsumi; Hoshino Masaru
        Seibutsu Butsuri, 2014
      • Interaction between soluble Aβ-(1-40) monomer and Aβ-(1-42) fibrils probed by paramagnetic relaxation enhancement
        Takahiro Yamaguchi; Katsumi Matsuzaki; Masaru Hoshino
        FEBS Letters, 18 Mar. 2013, Peer-reviewed
      • Interaction between isolated transcriptional activation domains of Sp1 revealed by heteronuclear magnetic resonance
        Naoko Hiramatsu; Emi Hibino; Katsumi Matsuzaki; Jun Kuwahara; Masaru Hoshino
        PROTEIN SCIENCE, Oct. 2012, Peer-reviewed
      • GM1 Cluster Mediates Formation of Toxic A beta Fibrils by Providing Hydrophobic Environments
        Saori Fukunaga; Hiroshi Ueno; Takahiro Yamaguchi; Yoshiaki Yano; Masaru Hoshino; Katsumi Matsuzaki
        BIOCHEMISTRY, Oct. 2012, Peer-reviewed
      • Structure-Activity Relationship Study of a CXC Chemokine Receptor Type 4 Antagonist, FC131, Using a Series of Alkene Dipeptide Isosteres
        Kazuya Kobayashi; Shinya Oishi; Ryoko Hayashi; Kenji Tomita; Tatsuhiko Kubo; Noriko Tanahara; Hiroaki Ohno; Yasushi Yoshikawa; Toshio Furuya; Masaru Hoshino; Nobutaka Fujii
        JOURNAL OF MEDICINAL CHEMISTRY, Mar. 2012, Peer-reviewed
      • Mechanism of Amyloid beta-Protein Aggregation Mediated by GM1 Ganglioside Clusters
        Keisuke Ikeda; Takahiro Yamaguchi; Saori Fukunaga; Masaru Hoshino; Katsumi Matsuzaki
        BIOCHEMISTRY, Jul. 2011, Peer-reviewed
      • Transient formation of intermediate conformational states of amyloid-beta peptide revealed by heteronuclear magnetic resonance spectroscopy
        Takahiro Yamaguchi; Katsumi Matsuzaki; Masaru Hoshino
        FEBS LETTERS, Apr. 2011, Peer-reviewed
      • Ganglioside-mediated aggregation of amyloid beta-proteins (A beta): comparison between A beta-(1-42) and A beta-(1-40)
        Mariko Ogawa; Miho Tsukuda; Takahiro Yamaguchi; Keisuke Ikeda; Takuma Okada; Yoshiaki Yano; Masaru Hoshino; Katsumi Matsuzaki
        JOURNAL OF NEUROCHEMISTRY, Mar. 2011, Peer-reviewed
      • 2G1648 Construction of the chaperonin-encapsulation system(Protein: Structure 2,The 48th Annual Meeting of the Biophysical Society of Japan)
        Ishino So; Masuhara Yasuhide; Kawata Yasushi; Matsuzaki Katsumi; Hoshino Masaru
        Seibutsu Butsuri, 2011
      • 1A1312 Mechanism of amyloid formation by Aβ in raft-like membranes containing ganglioside clusters(Biol & Artifi memb 1: Structure & Property, Dynamics,The 49th Annual Meeting of the Biophysical Society of Japan)
        Ikeda Keisuke; Yamaguchi Takahiro; Fukunaga Saori; Hoshino Masaru; Matsuzaki Katsumi
        Seibutsu Butsuri, 2011
      • A Disulfide-Linked Amyloid-beta Peptide Dimer Forms a Protofibril-like Oligomer through a Distinct Pathway from Amyloid Fibril Formation
        Takahiro Yamaguchi; Hisashi Yagi; Yuji Goto; Katsumi Matsuzaki; Masaru Hoshino
        BIOCHEMISTRY, Aug. 2010, Peer-reviewed
      • Chaperonin-encapsulation of proteins for NMR
        S. Tanaka; Y. Kawata; G. Otting; N.E. Dixon; K. Matsuzaki; M. Hoshino
        Biochimica et Biophysica Acta - Proteins and Proteomics, Apr. 2010, Peer-reviewed
      • Chaperonin-encapsulation of proteins for NMR
        Shinji Tanaka; Yasushi Kawata; Gottfried Otting; Nicholas E. Dixon; Katsumi Matsuzaki; Masaru Hoshino
        BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, Apr. 2010
      • Effects of macromolecular crowding on intracellular diffusion from a single particle perspective
        Damien Hall; Masaru Hoshino
        Biophysical Reviews, 2010, Peer-reviewed
      • 2P-051 Mechanism of amyloid β-protein aggregation mediated by GM1 ganglioside cluster(Protein:Property,The 47th Annual Meeting of the Biophysical Society of Japan)
        Ikeda Keisuke; Hoshino Masaru; Matsuzaki Katsumi
        Seibutsu Butsuri, 2009
      • 3P-061 A novel method for the structural analysis of self-associating proteins by high-resolution solution NMR spectroscopy(The 46th Annual Meeting of the Biophysical Society of Japan)
        Tanaka Shinji; Kawata Yasushi; Matsuzaki Katsumi; Hoshino Masaru
        Seibutsu Butsuri, 2008
      • Dimethylsulfoxide-quenched hydrogen/deuterium exchange method to study amyloid fibril structure
        M. Hoshino; H. Katou; K.-i. Yamaguchi; Y. Goto
        Biochimica et Biophysica Acta - Biomembranes, Aug. 2007, Peer-reviewed
      • Cores and pH-dependent dynamics of ferredoxin-NADP(+) reductase revealed by hydrogen/deuterium exchange
        Young-Ho Lee; Kosuke Tamura; Masahiro Maeda; Masaru Hoshino; Kazumasa Sakurai; Satoshi Takahashi; Takahisa Ikegami; Toshiharu Hase; Yuji Goto
        JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2007, Peer-reviewed
      • Inhibitors of amyloid β-protein aggregation mediated by GM1-containing raft-like membranes
        K. Matsuzaki; T. Noguch; M. Wakabayashi; K. Ikeda; T. Okada; Y. Ohashi; M. Hoshino; H. Naiki
        Biochimica et Biophysica Acta - Biomembranes, Jan. 2007, Peer-reviewed
      • Inhibitors of amyloid beta-protein aggregation mediated by GM1-containing raft-like membranes
        Katsumi Matsuzaki; Taeko Noguch; Masaki Wakabayashi; Keisuke Ikeda; Takuma Okada; Yumiko Ohashi; Masaru Hoshino; Hironobu Naiki
        BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, Jan. 2007, Peer-reviewed
      • Identification of the n- and c-terminal substrate binding segments of Ferredoxin-NADP plus reductase by NMR
        M Maeda; YH Lee; T Ikegami; K Tamura; M Hoshino; T Yamazaki; M Nakayama; T Hase; Y Goto
        BIOCHEMISTRY, Aug. 2005, Peer-reviewed
      • Nuclear magnetic resonance characterization of the refolding intermediate of beta(2)-microglobulin trapped by non-native prolyl peptide bond
        A Kameda; M Hoshino; T Higurashi; S Takahashi; H Naiki; Y Goto
        JOURNAL OF MOLECULAR BIOLOGY, Apr. 2005, Peer-reviewed
      • Sensitivity-enhanced double-TROSY experiment for simultaneous measurement of one-bond N-15-H-1, N-15-C-13 ' and two-bond H-1-C-13 ' couplings
        M Hoshino; G Otting
        JOURNAL OF MAGNETIC RESONANCE, Dec. 2004, Peer-reviewed
      • Direct observation of A beta amyloid fibril growth and inhibition
        T Ban; M Hoshino; S Takahashi; D Hamada; K Hasegawa; H Naiki; Y Goto
        JOURNAL OF MOLECULAR BIOLOGY, Nov. 2004, Peer-reviewed
      • Conformational stability of amyloid fibrils of beta-microglobulin probed by guanidine-hydrochloride-induced unfolding
        T Narimoto; K Sakurai; A Okamoto; E Chatani; M Hoshino; K Hasegawa; H Naiki; Y Goto
        FEBS LETTERS, Oct. 2004, Peer-reviewed
      • [Conformational stability of amyloid fibril: nanoscale needle].
        Goto Y; Ban T; Hoshino M
        Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, May 2004, Peer-reviewed
      • Core and heterogeneity of beta(2)-microglobulin amyloid fibrils as revealed by H/D exchange
        KI Yamaguchi; H Katou; M Hoshino; K Hasegawa; H Naiki; Y Goto
        JOURNAL OF MOLECULAR BIOLOGY, Apr. 2004, Peer-reviewed
      • Increase in the conformational flexibility of beta(2)-microglobulin upon copper binding: A possible role for copper in dialysis-related amyloidosis
        J Villanueva; M Hoshino; H Katou; J Kardos; K Hasegawa; H Naiki; Y Goto
        PROTEIN SCIENCE, Mar. 2004, Peer-reviewed
      • Protein folding by the effects of macromolecular crowding
        N Tokuriki; M Kinjo; S Negi; M Hoshino; Y Goto; Urabe, I; T Yomo
        PROTEIN SCIENCE, Jan. 2004, Peer-reviewed
      • アミロイド線維の構造安定性−ナノスケールの針
        星野 大
        蛋白質・核酸・酵素,49(7 Suppl), 1091-1095, 2004, Peer-reviewed
      • アミロイド線維の構造安定化機構−ナノスケールの針
        星野 大
        化学,59(1), 50-51, 2004, Peer-reviewed
      • Conformational dynamics of beta(2)-microglobulin analyzed by reduction and reoxidation of the disulfide bond
        M Gozu; YH Lee; Y Ohhashi; M Hoshino; H Naiki; Y Goto
        JOURNAL OF BIOCHEMISTRY, Jun. 2003, Peer-reviewed
      • Structural analysis of amyloid-fibrils of β2-microglobulin
        HOSHINO Masaru
        生化学, 25 Feb. 2003, Peer-reviewed
      • Structural analysis of amyloid-fibrils of beta 2-microglobulin
        M Hoshino
        SEIKAGAKU, Feb. 2003, Peer-reviewed
      • NMR analysis of the native and acid denatured β2-microglobulin proline mutants
        Kameda A.; Hoshino M.; Higurashi T.; Hagihara Y.; Naiki H.; Goto Y.
        Seibutsu Butsuri, 2003
      • Various stability of amyloid fibrils formed under different conditions
        Okamoto A.; Narimoto T.; Chatani E.; Hoshino M.; Hasegawa K.; Naiki H.; Goto Y.
        Seibutsu Butsuri, 2003
      • The interaction of beta(2)-glycoprotein I domain V with chaperonin GroEL: The similarity with the domain V and membrane interaction
        M Gozu; M Hoshino; T Higurashi; H Kato; Y Goto
        PROTEIN SCIENCE, Dec. 2002, Peer-reviewed
      • The role of disulfide bond in the amyloidogenic state of beta(2)-microglobulin studied by heteronuclear NMR
        H Katou; T Kanno; M Hoshino; Y Hagihara; H Tanaka; T Kawai; K Hasegawa; H Naiki; Y Goto
        PROTEIN SCIENCE, Sep. 2002, Peer-reviewed
      • Partially folded structure of flavin adenine dinucleotide-depleted ferredoxin-NADP(+) reductase with residual NADP(+) binding domain
        M Maeda; D Hamada; M Hoshino; Y Onda; T Hase; Y Goto
        JOURNAL OF BIOLOGICAL CHEMISTRY, May 2002, Peer-reviewed
      • Mapping the core of the beta(2)-microglobulin amyloid fibril by H/D exchange
        M Hoshino; H Katou; Y Hagihara; K Hasegawa; H Naiki; Y Goto
        NATURE STRUCTURAL BIOLOGY, May 2002, Peer-reviewed
      • Amyloid fibril formation of beta 2-microglobulin
        Y. Goto; M. Hoshino
        Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, May 2002, Peer-reviewed
      • Amyloid fibril formation of the mouse V-L domain at acidic pH
        SP Martsev; AP Dubnovitsky; AP Vlasov; M Hoshino; K Hasegawa; H Naiki; Y Goto
        BIOCHEMISTRY, Mar. 2002, Peer-reviewed
      • Aggregation of beta(2)-glycoprotein I induced by sodium lauryl sulfate and lysophospholipids
        Y Hagihara; DP Hong; M Hoshino; K Enjyoji; H Kato; Y Goto
        BIOCHEMISTRY, Jan. 2002, Peer-reviewed
      • The intrachain disulfide bond of beta(2)-microglobulin is not essential for the immunoglobulin fold at neutral pH, but is essential for amyloid fibril formation at acidic pH
        Y Ohhashi; Y Hagihara; G Kozhukh; M Hoshino; K Hasegawa; Yamaguchi, I; H Naiki; Y Goto
        JOURNAL OF BIOCHEMISTRY, Jan. 2002, Peer-reviewed
      • β2ミクログロブリンのアミロイド繊維形成
        星野 大
        蛋白質・核酸・酵素,47(6), 663-669, 2002, Peer-reviewed
      • 2I615 Conformation of anyloid fibrils studied by nuclear magnetic resonance
        Hoshino M.; Katou H.; Ohhashi Y.; Hagihara Y.; Hasegawa K.; Naiki H.; Goto Y.
        Seibutsu Butsuri, 2002
      • 2I1645 Analysis of Structural Stability of beta2-Microglobulin Amyloid Fibris
        Narimoto T.; Hoshino M.; Kardos Jozsef; Hasegawa K.; Naiki H.; Goto Y.
        Seibutsu Butsuri, 2002
      • 2R1615 H/D exchange reaction of ferredoxin-NADP^+ reductase analyzed by NMR
        Tamura K.; Maeda M.; Hoshino M.; Yamazaki T.; Hase T.; Goto Y.
        Seibutsu Butsuri, 2002
      • β-ラクトグロブリンの低温変性状態の構造 (新世紀における蛋白質科学の進展) -- (第2部 蛋白質の構造・物性・進化)
        後藤 祐児; 加藤 秀典; 星野 大
        蛋白質核酸酵素, Aug. 2001, Peer-reviewed
      • Native-like beta-hairpin retained in the cold-denatured state of bovine beta-lactoglobulin
        H Katou; M Hoshino; H Kamikubo; CA Batt; Y Goto
        JOURNAL OF MOLECULAR BIOLOGY, Jul. 2001, Peer-reviewed
      • Mycoplasma fermentans lipoprotein M161Ag-induced cell activation is mediated by toll-like receptor 2: Role of N-terminal hydrophobic portion in its multiple functions
        M Nishiguchi; M Matsumoto; T Takao; M Hoshino; Y Shimonishi; S Tsuji; NA Begum; O Takeuchi; S Akira; K Toyoshima; T Seya
        JOURNAL OF IMMUNOLOGY, Feb. 2001, Peer-reviewed
      • Structural and kinetic characterization of early folding events in beta-lactoglobulin
        K Kuwata; R Shastry; H Cheng; M Hoshino; CA Batt; Y Goto; H Roder
        NATURE STRUCTURAL BIOLOGY, Feb. 2001, Peer-reviewed
      • Role of the intrachain disulfide bond of beta2-microglobulin on its amyloid fibril formation.
        Ohashi Y; Hagihara Y; Gennadiy Kozhukh; Hoshino M; Hasegawa K; Yamaguchi I; Naiki H; Kanno T; Kawai T; Goto Y
        Seibutsu Butsuri, 2001
      • Role of disulfide bond in the amyloid fibril formation of beta2-microglobulin by NMR
        Katou H; Hoshino M; Gennadiy Kozhukh; Hasegawa K; Naiki H; Goto Y
        Seibutsu Butsuri, 2001
      • Dimerization Interaction of Bovine beta-Lactoglobulin Studied by Amino Acid Substitution.
        Sakurai K; Hoshino M; Goto Y
        Seibutsu Butsuri, 2001
      • Identification of the phospholipid-binding site of human beta(2)-glycoprotein I domain V by heteronuclear magnetic resonance
        M Hoshino; Y Hagihara; Nishii, I; T Yamazaki; H Kato; Y Goto
        JOURNAL OF MOLECULAR BIOLOGY, Dec. 2000, Peer-reviewed
      • Conformation and stability of thiol-modified bovine beta-lactoglobulin
        K Sakai; K Sakurai; M Sakai; M Hoshino; Y Goto
        PROTEIN SCIENCE, Sep. 2000, Peer-reviewed
      • Is folding of beta-Lactoglobulin non-hierarchic? Intermediate with native-like beta-sheet and non-native alpha-helix
        Forge, V; M Hoshino; K Kuwata; M Arai; K Kuwajima; CA Batt; Y Goto
        JOURNAL OF MOLECULAR BIOLOGY, Mar. 2000, Peer-reviewed
      • Expression of human bete2-microglobulin by Pichia pastoris
        Ohhash Y.; Hagihara Y.; Hoshino I.; Yamaguchi I.; Hasegawa K.; Naiki H.; Goto Y.
        Seibutsu Butsuri, 2000
      • Structural analysis of thiol modified beta-lactoglobulin by using NMR
        Kashiwai H.; Sakai K.; Sakurai K.; Hoshino M.; Goto Y.
        Seibutsu Butsuri, 2000
      • Interaction of labeled beta-Lactoglobulin with chaperonin GroEL
        Sakai K.; Yamasaki R.; Hoshino H.; Kawata Y.; Goto Y.
        Seibutsu Butsuri, 2000
      • Structural characterization of the cold-denatured state of beta-lactoglobulin
        Katou H.; Hoshino M.; Goto Y.
        Seibutsu Butsuri, 2000
      • Folding intermediate of beta-lactoglobulin
        Kuwata K.; Goto Y.; Hoshino M.; Heinrich Roder
        Seibutsu Butsuri, 2000
      • Solution structure and dynamics of bovine beta-lactoglobulin A
        K Kuwata; M Hoshino; Forge, V; S Era; CA Batt; Y Goto
        PROTEIN SCIENCE, Nov. 1999, Peer-reviewed
      • Single molecular observation of the interaction of GroEL with substrate proteins
        R Yamasaki; M Hoshino; T Wazawa; Y Ishii; T Yanagida; Y Kawata; T Higurashi; K Sakai; J Nagai; Y Goto
        JOURNAL OF MOLECULAR BIOLOGY, Oct. 1999, Peer-reviewed
      • Clustering of fluorine-substituted alcohols as a factor responsible for their marked effects on proteins and peptides
        DP Hong; M Hoshino; R Kuboi; Y Goto
        JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Sep. 1999, Peer-reviewed
      • Dynamic stability of bovine beta-lactoglobulin studied by hydrogen/deuterium exchange
        Forge, V; M Hoshino; K Kuwata; CA Batt; Y Goto
        OLD AND NEW VIEWS OF PROTEIN FOLDING, 1999, Peer-reviewed
      • Folding of beta-lactoglobulin, a case of the inconsistency of local and non-local interactions
        Y Goto; M Hoshino; K Kuwata; CA Batt
        OLD AND NEW VIEWS OF PROTEIN FOLDING, 1999, Peer-reviewed
      • Folding process of β-lactoglobulin
        Kuwata K.; Li H.; Yamada H.; Hoshino M.; Era S.; Goto Y.; Akasaka K.; Batt C. A.; Roder H.
        Seibutsu Butsuri, 1999
      • Interaction of DTNB Labeled β-Lactoglobulin with Chaperonin GroEL.
        Sakai K.; Yamasaki R.; Hoshino M.; Kawata Y.; Goto Y.
        Seibutsu Butsuri, 1999
      • Ligand binding mechanism of β-lactoglobulin
        Taguchi M.; Hoshino M; Aimoto S.; Goto Y.
        Seibutsu Butsuri, 1999
      • Single molecular observation of the interaction of GroEL with substrate proteins
        Yamasaki T.; Sakai K.; Hoshino M.; Wasawa T.; Ishi Y.; Kawata Y.; Yanagida T.; Goto Y.
        Seibutsu Butsuri, 1999
      • Folding of beta-lactoglobulin analyzed by NMR
        Hoshino Masaru; Forge Vincent; Kuwata Kazuo; Goto Yuii
        Seibutsu Butsuri, 1999
      • alpha ->beta transition of beta-lactoglobulin as evidenced by heteronuclear NMR
        K Kuwata; M Hoshino; S Era; CA Batt; Y Goto
        JOURNAL OF MOLECULAR BIOLOGY, Nov. 1998, Peer-reviewed
      • Chain-like conformation of heat-denatured ribonuclease A and cytochrome c as evidenced by solution X-ray scattering
        Y Hagihara; M Hoshino; D Hamada; M Kataoka; Y Goto
        FOLDING & DESIGN, 1998, Peer-reviewed
      • Trifluoroethanol-induced conformational transition of hen egg-white lysozyme studied by small-angle X-ray scattering
        M Hoshino; Y Hagihara; D Hamada; M Kataoka; Y Goto
        FEBS LETTERS, Oct. 1997, Peer-reviewed
      • Design and characterization of the anion-sensitive coiled-coil peptide
        M Hoshino; N Yumoto; S Yoshikawa; Y Goto
        PROTEIN SCIENCE, Jul. 1997, Peer-reviewed
      • Interaction of GroEL with conformational states of horse cytochrome c
        Masaru Hoshino; Yasushi Kawata; Yuji Goto
        Journal of Molecular Biology, 04 Oct. 1996, Peer-reviewed
      • 分子シャペロンは基質蛋白質の何を認識するか
        星野 大
        バイオサイエンスとインダストリー,53, 1054-1056, 1995, Peer-reviewed
      • PERCHLORATE-INDUCED FORMATION OF THE ALPHA-HELICAL STRUCTURE OF MASTOPARAN
        M HOSHINO; Y GOTO
        JOURNAL OF BIOCHEMISTRY, Oct. 1994, Peer-reviewed
      • ACID-INDUCED UNFOLDING AND REFOLDING TRANSITIONS OF CYTOCHROME-C - A 3-STATE MECHANISM IN H2O AND D2O
        Y GOTO; Y HAGIHARA; D HAMADA; M HOSHINO; NISHII, I
        BIOCHEMISTRY, Nov. 1993, Peer-reviewed
      • INTERMEDIATE CONFORMATIONAL STATES OF APOCYTOCHROME-C
        D HAMADA; M HOSHINO; M KATAOKA; AL FINK; Y GOTO
        BIOCHEMISTRY, Oct. 1993, Peer-reviewed

      Misc.

      • タンパク質の構造破綻とその関連疾患 物性化学から臨床まで 細胞内におけるユビキチン陽性タンパク質凝集体の形成機構の解明
        森本 大智; ヴァリンダ・エリック; 深田 はるみ; 菅瀬 謙治; 蔭山 俊; 星野 大; 難波 啓一; 小松 雅明; 田中 啓二; 白川 昌宏
        日本生化学会大会プログラム・講演要旨集, Sep. 2016
      • Relationship between Aggregation of Amyloid-beta Protein on Cells and Cytotoxicity
        Naoya Itoh; Eri Takada; Yoshiaki Yano; Masaru Hoshino; Katsumi Matsuzaki
        BIOPHYSICAL JOURNAL, Feb. 2016
      • Glutamine-rich activation domain of transcription factor Sp1-biochemical activity and structure
        Jun Kuwahara; Chisana Uwatoko; Emi Hibino; Katsumi Matsuzaki; Masaru Hoshino
        PROTEIN SCIENCE, Oct. 2015
      • Identification of toxic A beta aggregates and cross seeding between A beta 40 and A beta 42 on neuronal cells
        N. Itoh; E. Takada; Y. Yano; M. Hoshino; K. Matsuzaki
        EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, Jul. 2015
      • The Presence of Antiparallel Beta-Sheets in Toxic Fibrils Formed by ABeta on GM1 Clusters
        Yuki Okada; Hiroshi Ueno; Yoshiaki Yano; Masaru Hoshino; Hikari Itoh-Watanabe; Akira Naito; Katsumi Matsuzaki
        BIOPHYSICAL JOURNAL, Jan. 2015
      • ユビキチン化に伴うタンパク質構造不安定化
        森本大智; WALINDA Erik; 菅瀬謙治; 深田はるみ; 曽友深; 蔭山俊; 蔭山俊; 星野大; 藤井高志; 土屋光; 佐伯泰; 有田恭平; 有吉眞理子; 杤尾豪人; 岩井一宏; 難波啓一; 難波啓一; 小松雅明; 小松雅明; 田中啓二; 白川昌宏
        Abstracts. Annual Meeting of the NMR Society of Japan, 2014
      • Mechanism of Amyloid β-Protein Aggregation Mediated by GM1 Ganglioside Clusters
        MATSUZAKI Katsumi; IKEDA Keisuke; YAMAGUCHI Takahiro; FUKUNAGA Saori; HOSHINO Masaru
        Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2012
      • Low-Polarity Environment is Important for the Formation of Toxic Amyloid β Aggregates
        FUKUNAGA Saori; YAMAGUCHI Takahiro; YANO Yoshiaki; HOSHINO Masaru; MATSUZAKI Katsumi
        Peptide science : proceedings of the ... Japanese Peptide Symposium, 01 Mar. 2012
      • Mechanism of amyloid formation by A beta in raft-like membranes containing ganglioside clusters
        Keisuke Ikeda; Takahiro Yamaguchi; Saori Fukunaga; Masaru Hoshino; Katsumi Matsuzaki
        EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, Aug. 2011
      • ガングリオシドクラスターを介したアミロイドβタンパク質(Aβ)の凝集:Aβ-(1-40)とAβ-(1-42)の比較
        小川麻里子; 佃実保; 山口貴宏; 池田恵介; 岡田琢磨; 矢野義明; 星野大; 松崎勝巳
        生体膜と薬物の相互作用シンポジウム講演要旨集, 2010
      • Dimethylsulfoxide-quenched hydrogen/deuterium exchange method to study amyloid fibril structure
        Masaru Hoshino; Hidenori Katou; Kei-Ichi Yamaguchi; Yuji Goto
        BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, Aug. 2007
      • ラフト様脂質膜存在下で形成されたアミロイドβ蛋白質線維の構造解析
        池田恵介; 矢野義明; 星野大; 松崎勝巳
        日本薬学会年会要旨集, 2006
      • Structural analysis of amyloid-ß protein fibrils formed in raft-like model membranes.
        Keisuke Ikeda; Yoshiaki Yano; Masaru Hoshino; Kazuhiro Hasegawa; Hironobu Naiki; Youhei Sohma; Yoshio Hayashi; Yoshiaki Kiso; Katsumi Matsuzaki
        Peptide Science 2006, 2006
      • β2-ミクログロブリンのフォールディングとアミロイド線維形成
        内木宏延; 後藤祐児; 星野 大; 長谷川一浩
        厚生労働科学研究費補助金特定疾患対策研究事業アミロイドーシスに関する調査研究平成14年度総括研究報告書, 2003
      • Urea unfolding of ferredoxin-NADP^+ reductase
        Tamura K; Maeda M; Hoshino M; Ikegami T; Yamazaki T; Hase T; Goto Y
        Seibutsu Butsuri, 2003
      • β2ミクログロブリンのアミロイド線維形成 (特集 蛋白質フォールディングの諸問題)
        後藤 祐児; 星野 大
        蛋白質核酸酵素, May 2002
      • Structural analysis of ferredoxin-NADP(+) reductase and substrate complex by nuclear magnetic resonance
        M Maeda; M Hoshino; T Yamazaki; T Hase; Y Goto
        PLANT AND CELL PHYSIOLOGY, 2002
      • α→β transition and structural fluctuation in β lactoglobulin.
        Kuwata K.; Hoshino M.; Goto Y.; Era S.; Batt C.A.
        Biophysics, 07 Sep. 1998
      • The folding intermediate state of β-lactoglobulin.
        Hoshino M.; Forge V.; Kuwata K.; Batt C.A.; Goto Y.
        Biophysics, 07 Sep. 1998
      • Folding of beta-lactoglobulin and interaction with GroE
        HOSHINO M.; HIROTA N.; KUWATA K.; KAWATA Y.; BATT Carl A.; GOTO Y.
        Biophysics, Oct. 1997
      • NMR structure and dynamics of β lactoblobulin
        KUWATA K.; HOSHINO M.; GOTO Y.; BATT Carl. A.; ERA S.
        Biophysics, Oct. 1997
      • 大腸菌GroELの基質蛋白質認識機構
        後藤 祐児; 星野 大
        日本分子生物学会年会プログラム・講演要旨集, Aug. 1996
      • 分子シャペロンは何を認識するのか?
        星野 大; 河田 康志; 溝端 知宏; 永井 純; 後藤 祐児
        日本分子生物学会年会プログラム・講演要旨集, 01 Aug. 1996

      Presentations

      • Dynamic equilibrium between oligomeric states of amyloid-beta peptide studied by solution NMR
        Masaru HOSHINO
        The 3rd Ulm Meeting – Biophysics of Amyloid Formation, 21 Feb. 2019
      • アミロイドβペプチド凝集初期過程の解析
        星野 大; 中川 大雅; 釣 大佑; 西井 一郎
        第10回 タンパク質の異常凝集とその防御・修復機構に関する研究会, 11 Dec. 2018
      • シャペロニンGroEのフットボール型複合体におけるリング交換反応
        石野 聡; 矢野 義明; 河田 康志; 松崎 勝巳; 星野 大
        第91回日本生化学会大会, 25 Sep. 2018
      • 高分解能溶液NMRによるアミロイドβ凝集初期過程の解析
        中川 大雅; 西井 一郎; 松崎 勝巳; 星野 大
        第18回日本蛋白質科学会年会, 28 Jun. 2018
      • 転写因子Sp1とTAF4の相互作用の分子機構
        日比野 絵美; 井上 倫太郎; 杉山 正明; 桑原 淳; 松崎 勝巳; 星野 大
        第52回 京都大学原子炉実験所学術講演会, 25 Jan. 2018
      • 転写因子Sp1とTAF4の相互作用領域のNMR解析
        日比野 絵美; 井上 倫太郎; 杉山 正明; 桑原 淳; 松崎 勝巳; 星野 大
        第17回日本蛋白質科学会年会, 22 Jun. 2017
      • Interaction between intrinsically disordered regions in transcription factors Sp1 and TAF4.
        E. Hibino; J. Kuwahara; K. Matsuzaki; M. Hoshino
        XXVIIth Internatinal Conference on Magnetic Resonance in Biological Systems, 22 Aug. 2016
      • Interaction between intrinsically disordered regions in transcription factors Sp1 and TAF4.Interaction between intrinsically disordered regions in transcription factors Sp1 and TAF4
        E. Hibino; R. Inoue; M. Sugiyama; J. Kuwahara; K. Matsuzaki; M. Hoshino
        The 30th Anniversary Symposium of the Protein Society, 16 Jun. 2016
      • 分子シャペロン Cdc37 のリン酸化による構造転移機構
        井濱 太; 山本 麻実; 宮田 愛彦; 松崎 勝巳; 星野 大
        第16回日本蛋白質科学会年会, 08 Jun. 2016
      • The interaction between transcription factors Sp1 and TAF4 via the intrinsically disordered regions.
        Masaru HOSHINO
        Protein Structure and Function (IPR x RSC Joint Symposium), 15 Nov. 2015
      • Sp1 と TAF4 の天然変性領域を介した相互作用の解析
        日比野 絵美; 井上 倫太郎; 杉山 正明; 桑原 淳; 松崎 勝巳; 星野 大
        24 Jun. 2015
      • The presence of antiparallel beta-sheets in toxic fibrils formed by abeta on GM1 clusters.
        Y. Okada; H. Ueno; Y. Yano; M. Hoshino; H.I. Watanabe; A. Naito; K. Matsuzaki
        Biophysical society 59th annual meeting, 11 Feb. 2015
      • New Insights into the Reaction Mechanism of Molecular Chaperone GroE.
        Masaru HOSHINO
        IPR symposium - Molecular Crowding and Macromolecular Association, 05 Feb. 2015

      Books and Other Publications

      • 第2章 立体構造 (2) 多次元NMR
        星野 大
        タンパク質科学(後藤祐児、桑島邦博、谷澤克行 偏) 化学同人,, 2005, Not refereed
      • 14.6節 旋光性と円二色性 14.6.4項 生体物質
        星野 大
        化学便覧基礎編改訂5版(岩澤康裕他編)\t 丸善株式会社出版事業部,II-653-654, 2004, Not refereed
      • シリーズ・ニューバイオフィジックス第1巻「タンパク質のかたちと物性」第2章2-2フォールディング中間状態(分担執筆)
        星野 大
        共立出版株式会社,, 1997, Not refereed

      External funds: others

      • Folding Mechanism of bovine β-lactoglobulin
      • Substrate recognition mechanism of molecular chaperone GroE.
      • Structure and function of β2-glycoprotein (]G0001[)
      list
        Last Updated :2026/10/20

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          Introduction to Physical Chemistry for Drug Discovery
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          Advanced Basic Physical Chemistry I
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          Basic Laboratory Techniques in Physical Chemistry
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          Seminar in Basic Biophysical Chemistry
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          Basic Science Seminar
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          Research in Basic Biophysical Chemistry
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          Research in Basic Biophysical Chemistry
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          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
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          Research in Basic Biophysical Chemistry
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          Basic Science Seminar
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          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
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          Basic Laboratory Techniques in Physical Chemistry
          1206, Spring, Graduate School of Pharmaceutical Sciences, 2
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          Physical Chemistry IV (Biophysical Chemistry)
          C104, Fall, Faculty of Pharmaceutical Sciences, 2
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          Seminar in Basic Biophysical Chemistry
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          Physical Chemistry 4 (Biophysical Chemistry)
          A104, Fall, Faculty of Pharmaceutical Sciences, 2
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          21COE化学講義3(理)
          8001, Spring, Graduate School of Pharmaceutical Sciences, 2
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          Introduction to Physical Chemistry for Drug Discovery
          8101, Spring, Graduate School of Pharmaceutical Sciences, 2
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          Introduction to Physical Chemistry for Drug Discovery
          1217, Spring, Graduate School of Pharmaceutical Sciences, 2
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          Advanced Basic Physical Chemistry I
          1211, Spring, Graduate School of Pharmaceutical Sciences, 2
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          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          A901, Spring, Faculty of Pharmaceutical Sciences, 4
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          Advanced Physical Chemistry for Drug Discovery A
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          Basic Physical Chemistry (thermodynamics)
          N340, Fall, Institute for Liberal Arts and Sciences, 2
        • From Apr. 2011, To Mar. 2012
          Fundamental Physical Chemistry for Pharmaceutical Sciences
          Fall, 全学共通科目
        • From Apr. 2011, To Mar. 2012
          Frontier in pharmaceutical science
          Fall, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Introduction to Basic Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Advanced Basic Physical Chemistry II
          Spring, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Laboratory Practice in Basic Analytical Chemistry and
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2011, To Mar. 2012
          物理化学4(生物物理化学)
          Fall, 薬学部
        • From Apr. 2011, To Mar. 2012
          生物物理化学
          Fall, 薬学部
        • From Apr. 2011, To Mar. 2012
          薬学専門実習1
          Spring, 薬学部
        • From Apr. 2012, To Mar. 2013
          Frontier in pharmaceutical science
          Fall, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Medicinal Physical Chemistry Exercise 1
          Spring, 薬学部
        • From Apr. 2012, To Mar. 2013
          Physical Sciences for Drug Discovery
          Spring, 全学共通科目
        • From Apr. 2012, To Mar. 2013
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Introduction to Basic Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Advanced Basic Physical Chemistry I
          Spring, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2012, To Mar. 2013
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2012, To Mar. 2013
          Biophysical Chemistry
          Fall, 薬学部
        • From Apr. 2012, To Mar. 2013
          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2012, To Mar. 2013
          Pharmaceutical Laboratory I :Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2012, To Mar. 2013
          Fundamental Physical Chemistry for Pharmaceutical Sciences (Chemical Thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2013, To Mar. 2014
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2013, To Mar. 2014
          Medicinal Physical Chemistry Exercise 1
          Spring, 薬学部
        • From Apr. 2013, To Mar. 2014
          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2013, To Mar. 2014
          Introduction to Basic Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Advanced Basic Physical Chemistry II
          Spring, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Frontier in pharmaceutical science
          Fall, 薬学研究科
        • From Apr. 2013, To Mar. 2014
          Fundamental Physical Chemistry for Pharmaceutical Sciences (Chemical Thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2013, To Mar. 2014
          Physical Sciences for Drug Discovery
          Spring, 全学共通科目
        • From Apr. 2014, To Mar. 2015
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2014, To Mar. 2015
          Medicinal Physical Chemistry Exercise 1
          Spring, 薬学部
        • From Apr. 2014, To Mar. 2015
          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2014, To Mar. 2015
          Introduction to Basic Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Advanced Basic Physical Chemistry I
          Spring, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2014, To Mar. 2015
          Fundamental Physical Chemistry for Pharmaceutical Sciences (Chemical Thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2014, To Mar. 2015
          Physical Sciences for Drug Discovery
          Spring, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Medicinal Physical Chemistry Exercise 1
          Spring, 薬学部
        • From Apr. 2015, To Mar. 2016
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Introduction to Basic Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Advanced Basic Physical Chemistry II
          Spring, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2015, To Mar. 2016
          Basic Physical Chemistry (thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2015, To Mar. 2016
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2015, To Mar. 2016
          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2016, To Mar. 2017
          Medicinal Physical Chemistry Exercise 1
          Spring, 薬学部
        • From Apr. 2016, To Mar. 2017
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Introduction to Basic Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Advanced Basic Physical Chemistry I
          Spring, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2016, To Mar. 2017
          Basic Physical Chemistry (thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2016, To Mar. 2017
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2016, To Mar. 2017
          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2017, To Mar. 2018
          Medicinal Physical Chemistry Exercise 1
          Spring, 薬学部
        • From Apr. 2017, To Mar. 2018
          Introduction to Physical Chemistry for Drug Discovery
          Spring, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Advanced Basic Physical Chemistry II
          Spring, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2017, To Mar. 2018
          Basic Physical Chemistry (thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2017, To Mar. 2018
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2017, To Mar. 2018
          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2018, To Mar. 2019
          Medicinal Physical Chemistry Exercise 1
          Spring, 薬学部
        • From Apr. 2018, To Mar. 2019
          Introduction to Physical Chemistry for Drug Discovery
          Spring, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Advanced Basic Physical Chemistry I
          Spring, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2018, To Mar. 2019
          Fundamental Chemical Experiments
          Fall, 全学共通科目
        • From Apr. 2018, To Mar. 2019
          Basic Physical Chemistry (thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2018, To Mar. 2019
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2018, To Mar. 2019
          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2019, To Mar. 2020
          ILAS Seminar
          Spring, 全学共通科目
        • From Apr. 2019, To Mar. 2020
          Medicinal Physical Chemistry Exercise 1
          Spring, 薬学部
        • From Apr. 2019, To Mar. 2020
          Introduction to Physical Chemistry for Drug Discovery
          Spring, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Advanced Basic Physical Chemistry II
          Spring, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2019, To Mar. 2020
          Basic Physical Chemistry (thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2019, To Mar. 2020
          Basic Science Seminar
          Spring, 薬学部
        • From Apr. 2019, To Mar. 2020
          Physical Chemistry IV (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2019, To Mar. 2020
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2019, To Mar. 2020
          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2020, To Mar. 2021
          Introduction to Physical Chemistry for Drug Discovery
          Spring, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Basic Physical Chemistry I
          Spring, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Basic Physical Chemistry (thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2020, To Mar. 2021
          Basic Science Seminar
          Spring, 薬学部
        • From Apr. 2020, To Mar. 2021
          Physical Chemistry IV (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2020, To Mar. 2021
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2020, To Mar. 2021
          Basic Laboratory Techniques in Pharmaceutical Sciences
          Spring, 薬学研究科
        • From Apr. 2020, To Mar. 2021
          Pharmaceutical Laboratory I : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2020, To Mar. 2021
          Pharmaceutical Laboratory 1 : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2021, To Mar. 2022
          Introduction to Physical Chemistry for Drug Discovery
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Basic Laboratory Techniques in Physical Chemistry
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Basic Laboratory Techniques in Physical Chemistry
          Fall, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Basic Physical Chemistry II
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Laboratory Practice in Basic Analytical Chemistry and Structural Biology
          Year-long, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Research in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Seminar in Basic Biophysical Chemistry
          Year-long, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Fundamental Chemical Experiments
          Fall, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Basic Physical Chemistry (thermodynamics)
          Fall, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Basic Science Seminar
          Spring, 薬学部
        • From Apr. 2021, To Mar. 2022
          Physical Chemistry IV (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2021, To Mar. 2022
          Physical Chemistry 4 (Biophysical Chemistry)
          Fall, 薬学部
        • From Apr. 2021, To Mar. 2022
          Basic Laboratory Techniques in Pharmaceutical Sciences
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Pharmaceutical Laboratory I : Analytical and Physical Chemistry
          Spring, 薬学部
        • From Apr. 2021, To Mar. 2022
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