Basic Information

Academic Degree

• 博士（医学）(京都大学)

ID,URL

• J-Global ID

  201801014322013980

researchmap URL

• https://researchmap.jp/7000023120

Research

Papers

• Preclinical evaluation of a paclitaxel-incorporated nanoparticle-coated balloon in rabbit and porcine models

  Erika Yamamoto; Shin Watanabe; Bingyuan Bao; Hiroki Watanabe; Kenji Nakatsuma; Masayasu Izuhara; Koh Ono; Gaku Nakazawa; Takeshi Kimura; Naritatsu Saito

  Cardiovascular Revascularization Medicine, 01 Jun. 2018, Peer-reviewed

  
• Speckle-Tracking Echocardiographic Strain Analysis Reliably Estimates Degree of Acute LV Unloading During Mechanical LV Support by Impella.

  Hammoudi N; Watanabe S; Bikou O; Ceccaldi A; Fish K; Yamada KP; Miyashita S; Lebreton G; Hajjar RJ; Ishikawa K

  Journal of cardiovascular translational research, May 2018, Peer-reviewed

  
• Left Ventricular Unloading Using an Impella CP Improves Coronary Flow and Infarct Zone Perfusion in Ischemic Heart Failure.

  Watanabe S; Fish K; Kovacic JC; Bikou O; Leonardson L; Nomoto K; Aguero J; Kapur NK; Hajjar RJ; Ishikawa K

  Journal of the American Heart Association, Mar. 2018, Peer-reviewed

  
• Echocardiographic and hemodynamic assessment for predicting early clinical events in severe acute mitral regurgitation.

  Watanabe S; Fish K; Bonnet G; Santos-Gallego CG; Leonardson L; Hajjar RJ; Ishikawa K

  The international journal of cardiovascular imaging, Feb. 2018, Peer-reviewed

  
• Reduced longitudinal contraction is associated with ischemic mitral regurgitation after posterior MI.

  Ishikawa K; Watanabe S; Hammoudi N; Aguero J; Bikou O; Fish K; Hajjar RJ

  American journal of physiology. Heart and circulatory physiology, Feb. 2018, Peer-reviewed

  
• Coronary bifurcation model created using a novel directional heat injury catheter

  Kenji Nakatsuma; Shin Watanabe; Akihiro Tokushige; Erika Yamamoto; Bingyuan Bao; Hiroki Watanabe; Takeshi Kimura; Naritatsu Saito

  Cardiovascular Revascularization Medicine, 01 Jan. 2018, Peer-reviewed

  
• Protein Phosphatase Inhibitor-1 Gene Therapy in a Swine Model of Nonischemic Heart Failure

  Shin Watanabe; Kiyotake Ishikawa; Kenneth Fish; Jae Gyun Oh; Lukas J. Motloch; Erik Kohlbrenner; Philyoung Lee; Chaoqin Xie; Ahyoung Lee; Lifan Liang; Changwon Kho; Lauren Leonardson; Maritza McIntyre; Scott Wilson; R. Jude Samulski; Evangelia G. Kranias; Thomas Weber; Fadi G. Akar; Roger J. Hajjar

  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Oct. 2017, Peer-reviewed

  
• A novel guidewire-integrated embolic protection filter device with a handy-folding system: In vitro and in vivo performance assessment.

  Watanabe H; Saito N; Nagata Y; Yamamoto E; Nakatsuma K; Bingyuan B; Watanabe S; Tazaki J; Kimura T; Inoue K

  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Sep. 2017, Peer-reviewed

  
• Editorial Commentary: Clinical gene therapy trials for heart failure: Did they fail?

  Shin Watanabe; Kiyotake Ishikawa

  TRENDS IN CARDIOVASCULAR MEDICINE, Apr. 2017, Peer-reviewed

  
• Antegrade transcatheter aortic valve implantation using the looped Inoue balloon technique: A pilot study in a swine model

  Kenji Nakatsuma; Naritatsu Saito; Hiroki Watanabe; Bingyuan Bao; Erika Yamamoto; Shin Watanabe; Takeshi Kimura; Kanji Inoue

  JOURNAL OF CARDIOLOGY, Jan. 2017, Peer-reviewed

  
• Cardiac Gene Delivery in Large Animal Models: Antegrade Techniques.

  Watanabe S; Leonardson L; Hajjar RJ; Ishikawa K

  Methods in molecular biology (Clifton, N.J.), 2017, Peer-reviewed

  
• Ultrathin Endoscopy-Guided Pericardiocentesis: A Pilot Study in a Swine Model

  Kenji Nakatsuma; Erika Yamamoto; Shin Watanabe; Bingyuan Bao; Hiroki Watanabe; Yoshiaki Kawase; Satoshi Shizuta; Takeshi Kimura; Naritatsu Saito

  JOURNAL OF INVASIVE CARDIOLOGY, Mar. 2016, Peer-reviewed

  
• Prediction of the true fractional flow reserve of left main coronary artery stenosis with concomitant downstream stenoses: in vitro and in vivo experiments

  Erika Yamamoto; Naritatsu Saito; Hitoshi Matsuo; Yoshiaki Kawase; Shin Watanabe; Bingyuan Bao; Hiroki Watanabe; Hirooki Higami; Kenji Nakatsuma; Takeshi Kimura

  EUROINTERVENTION, Feb. 2016, Peer-reviewed

  
• A novel equitation to predict the pressure derived collateral flow index in multiple sequential coronary stenoses

  Yoshiaki Kawase; Naritatsu Saito; Shin Watanabe; Bingyuan Bao; Erika Yamamoto; Hiroki Watanabe; Hirooki Higami; Kenji Nakatsuma; Takeshi Kimura; Hitoshi Matsuo

  Cardiovascular Intervention and Therapeutics, 01 Jul. 2015, Peer-reviewed

  
• Patient-Specific Three-Dimensional Aortocoronary Model for Percutaneous Coronary Intervention of a Totally Occluded Anomalous Right Coronary Artery.

  Hirotoshi Watanabe; Naritatsu Saito; Syojiro Tatsushima; Junichi Tazaki; Toshiaki Toyota; Masao Imai; Shin Watanabe; Erika Yamamoto; Bingyuan Bao; Kenji Nakatsuma; Hiroki Watanabe; Satoshi Shizuta; Takeshi Kimura

  The Journal of invasive cardiology, Jul. 2015, Peer-reviewed

  
• Intravascular ultrasound observation of an obstruction of the left main coronary artery caused by displaced leaflet calcification and hematoma after transcatheter aortic valve implantation.

  Tomohiko Taniguchi; Naritatsu Saito; Kenji Minakata; Masao Imai; Hirotoshi Watanabe; Toshiaki Toyota; Shin Watanabe; Junichi Tazaki; Shigeki Koizumi; Shingo Hirao; Kazuhiro Yamazaki; Hiroki Daijo; Ryuzo Sakata; Takeshi Kimura

  Circulation, 17 Feb. 2015, Peer-reviewed

  
• MicroRNA-451 Exacerbates Lipotoxicity in Cardiac Myocytes and High-Fat Diet-Induced Cardiac Hypertrophy in Mice Through Suppression of the LKB1/AMPK Pathway

  Yasuhide Kuwabara; Takahiro Horie; Osamu Baba; Shin Watanabe; Masataka Nishiga; Shunsuke Usami; Masayasu Izuhara; Tetsushi Nakao; Tomohiro Nishino; Kinya Otsu; Toru Kita; Takeshi Kimura; Koh Ono

  CIRCULATION RESEARCH, Jan. 2015, Peer-reviewed

  
• In vitro assessment of physiological impact of recipient artery intervention on the contralateral donor artery

  Hiroki Watanabe; Naritatsu Saito; Hitoshi Matsuo; Yoshiaki Kawase; Shin Watanabe; Bingyuan Bao; Erika Yamamoto; Hirooki Higami; Kenji Nakatsuma; Takeshi Kimura

  Cardiovascular Revascularization Medicine, 2015, Peer-reviewed

  
• Cardiac-Specific Inhibition of Kinase Activity in Calcium/Calmodulin-Dependent Protein Kinase Kinase-beta Leads to Accelerated Left Ventricular Remodeling and Heart Failure after Transverse Aortic Constriction in Mice

  Shin Watanabe; Takahiro Horie; Kazuya Nagao; Yasuhide Kuwabara; Osamu Baba; Hitoo Nishi; Naoya Sowa; Michiko Narazaki; Tetsuya Matsuda; Genzou Takemura; Hiromichi Wada; Koji Hasegawa; Takeshi Kimura; Koh Ono

  PLOS ONE, Sep. 2014, Peer-reviewed

  Access this paper :

  
• Utility of a scoring balloon for a severely calcified lesion: Bench test and finite element analysis

  Yoshiaki Kawase; Naritatsu Saito; Shin Watanabe; Bingyuan Bao; Erika Yamamoto; Hiroki Watanabe; Hirooki Higami; Hitoshi Matsuo; Katsumi Ueno; Takeshi Kimura

  Cardiovascular Intervention and Therapeutics, 2014, Peer-reviewed

  
• In Vitro Assessment of Mathematically-Derived Fractional Flow Reserve in Coronary Lesions With More Than Two Sequential Stenoses

  Naritatsu Saito; Hitoshi Matsuo; Yoshiaki Kawase; Shin Watanabe; Bingyuan Bao; Erika Yamamoto; Hiroki Watanabe; Kenji Nakatsuma; Katsumi Ueno; Takeshi Kimura

  JOURNAL OF INVASIVE CARDIOLOGY, Dec. 2013, Peer-reviewed

  
• Microcatheter-facilitated reverse wire technique for side branch wiring in bifurcated vessels: an in vitro evaluation.

  Watanabe S; Saito N; Bao B; Tokushige A; Watanabe H; Yamamoto E; Kawase Y; Kimura T

  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Nov. 2013, Peer-reviewed

  
• A novel device for antegrade percutaneous balloon aortic valvuloplasty: feasibility of the looped Inoue balloon technique in swine model.

  Bingyuan Bao; Naritatsu Saito; Shin Watanabe; Akihiro Tokushige; Erika Yamamoto; Yoshiaki Kawase; Takeshi Kimura; Kanji Inoue

  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 01 Oct. 2013, Peer-reviewed

  
• Percutaneous balloon valvuloplasty for bioprosthetic mitral valve stenosis

  Yasuhiro Hamatani; Naritatsu Saito; Junichi Tazaki; Masahiro Natsuaki; Kentaro Nakai; Takeru Makiyama; Yasuhiro Sasaki; Masao Imai; Shin Watanabe; Tetsuo Shioi; Takeshi Kimura; Kanji Inoue

  HEART AND VESSELS, Sep. 2013, Peer-reviewed

  Access this paper :

  
• MicroRNA-33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE(-/-) Mice

  Takahiro Horie; Osamu Baba; Yasuhide Kuwabara; Yoshimasa Chujo; Shin Watanabe; Minako Kinoshita; Masahito Horiguchi; Tomoyuki Nakamura; Kazuhisa Chonabayashi; Masakatsu Hishizawa; Koji Hasegawa; Noriaki Kume; Masayuki Yokode; Toru Kita; Takeshi Kimura; Koh Ono

  JOURNAL OF THE AMERICAN HEART ASSOCIATION, Dec. 2012, Peer-reviewed

  
• MicroRNA 26b encoded by the intron of small CTD phosphatase (SCP) 1 has an antagonistic effect on its host gene

  Naoya Sowa; Takahiro Horie; Yasuhide Kuwabara; Osamu Baba; Shin Watanabe; Hitoo Nishi; Minako Kinoshita; Rieko Takanabe-Mori; Hiromichi Wada; Akira Shimatsu; Koji Hasegawa; Takeshi Kimura; Koh Ono

  JOURNAL OF CELLULAR BIOCHEMISTRY, Nov. 2012, Peer-reviewed

  
• A Novel Method to Deliver the Filtrap Coronary Embolic Protection Filter Using a Manual Thrombectomy Catheter: In Vitro and In Vivo Comparison with the Conventional Method

  Shin Watanabe; Naritatsu Saito; Akihiro Tokushige; Bao Bingyuan; Yoshiaki Kawase; Takeshi Kimura

  JOURNAL OF INVASIVE CARDIOLOGY, Apr. 2012, Peer-reviewed

  
• Impact of Platelet Reactivity on Long-term Clinical Outcomes and Bleeding Events in Japanese Patients Receiving Antiplatelet Therapy with Aspirin

  Keiichiro Yamane; Tomoyuki Ikeda; Ryoji Taniguchi; Shin Watanabe; Mitsunori Kawato; Hirokazu Kondo; Ryutaro Shirakawa; Tomohito Higashi; Masanao Toma; Arata Tabuchi; Toshihiro Tamura; Kanako Takahashi; Haruyo Watanabe; Yuka Yoshikawa; Toru Kita; Takeshi Kimura; Hisanori Horiuchi

  JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 2012, Peer-reviewed

  
• Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage

  Yasuhide Kuwabara; Koh Ono; Takahiro Horie; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Shin Watanabe; Osamu Baba; Yoji Kojima; Satoshi Shizuta; Masao Imai; Toshihiro Tamura; Toru Kita; Takeshi Kimura

  CIRCULATION-CARDIOVASCULAR GENETICS, Aug. 2011, Peer-reviewed

  
• MicroRNA-27a Regulates Beta Cardiac Myosin Heavy Chain Gene Expression by Targeting Thyroid Hormone Receptor beta 1 in Neonatal Rat Ventricular Myocytes

  Hitoo Nishi; Koh Ono; Takahiro Horie; Kazuya Nagao; Minako Kinoshita; Yasuhide Kuwabara; Shin Watanabe; Tomohide Takaya; Yodo Tamaki; Rieko Takanabe-Mori; Hiromichi Wada; Koji Hasegawa; Yoshitaka Iwanaga; Teruhisa Kawamura; Toru Kita; Takeshi Kimura

  MOLECULAR AND CELLULAR BIOLOGY, Feb. 2011, Peer-reviewed

  Access this paper :

  
• Insulin-like growth factor axis (insulin-like growth factor-I/insulin-like growth factor-binding protein-3) as a prognostic predictor of heart failure: association with adiponectin

  Shin Watanabe; Toshihiro Tamura; Koh Ono; Hisanori Horiuchi; Takeshi Kimura; Toru Kita; Yutaka Furukawa

  EUROPEAN JOURNAL OF HEART FAILURE, Nov. 2010, Peer-reviewed

  
• Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway

  Takahiro Horie; Koh Ono; Hitoo Nishi; Kazuya Nagao; Minako Kinoshita; Shin Watanabe; Yasuhide Kuwabara; Yasuhiro Nakashima; Rieko Takanabe-Mori; Eiichiro Nishi; Koji Hasegawa; Toru Kita; Takeshi Kimura

  CARDIOVASCULAR RESEARCH, Sep. 2010, Peer-reviewed

  
• Characterization of the Antiplatelet Effect of Aspirin at Enrollment and After 2-Year Follow-up in a Real Clinical Setting in Japan

  Tomoyuki Ikeda; Ryoji Taniguchi; Shin Watanabe; Mitsunori Kawato; Hirokazu Kondo; Ryutaro Shirakawa; Keiichiro Yamane; Masanao Toma; Toshihiro Tamura; Kanako Takahashi; Haruyo Watanabe; Yuka Yoshikawa; Arata Tabuchi; Toru Kita; Takeshi Kimura; Hisanori Horiuchi

  CIRCULATION JOURNAL, Jun. 2010, Peer-reviewed

  

External funds: others

• 心筋内細胞注入カテーテルに関する研究開発 （2020年度分）

  医療研究開発推進事業費補助金

  From 01 Apr. 2020, To 31 Mar. 2021

  渡邉　真