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Fabian Raudzus

Graduate School of Medicine Assistant Professor

Fabian Raudzus
list
    Last Updated :2025/05/27

    Basic Information

    Faculty

    • 医学部
    • 国際高等教育院

    Professional Memberships

    • From Jan. 2022, To Present
      The Japan Neuroscience Society
    • From Jul. 2009, To Present
      German Society of Biochemistry and Molecular Biology (GBM)

    Academic Degree

    • M.S.(Ruhr-Universitat Bochum)
    • Dr.rer.Nat(Ruhr-Universitat Bochum)

    Language of Instruction

    • German

    ID,URL

    researchmap URL

    list
      Last Updated :2025/05/27

      Research

      Research Interests

      • Magnetic Nanoparticles
      • Ras GTPase
      • Cell Signaling
      • Neurodegenerative Diseases
      • Regenerative Medicine
      • Stem Cells

      Research Areas

      • Life sciences, Biomaterials, Magnetic Nanoparticles
      • Life sciences, Neuroscience - general, Neuronal Regeneration
      • Life sciences, Functional biochemistry, Cell Signaling
      • Life sciences, Applied molecular and cellular biology, Stem Cell Research

      Papers

      • Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model
        Sara De Vincentiis; Elena Capitanini; Karen Kira; Claudia Dell'Amico; Jun Takahashi; Marco Onorati; Fabian Raudzus; Vittoria Raffa
        Advanced Science, 11 May 2025
      • Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain
        Ryosuke Tsuchimochi; Keitaro Yamagami; Naoko Kubo; Naoya Amimoto; Fabian Raudzus; Bumpei Samata; Tetsuhiro Kikuchi; Daisuke Doi; Koji Yoshimoto; Aya Mihara; Jun Takahashi
        Stem Cell Reports, 23 Mar. 2023
      • Label free quantitative proteomic analysis of astrocytes directly converted to neurons
        Hendrik Schöneborn; Fabian Raudzus; Chakrabarty, Koushik; Sebastian Neumann; Heumann, Rolf; Islam, Shariful; Rolfes, Christina; Krüger, Marcus; Heumann, Hermann
        The FEBS journal / Federation of European Biochemical Societies, 2015
      • A comprehensive approach to characterize navigation instruments for magnetic guidance in biological systems.
        Peter Blümler; Fabian Raudzus; Friederike Schmid
        Scientific reports, 03 Apr. 2024, Corresponding author
      • Pretreatment with Perlecan-Conjugated Laminin-E8 Fragment Enhances Maturation of Grafted Dopaminergic Progenitors in Parkinson's Disease Model.
        Hiromasa Adachi; Asuka Morizane; Sadaharu Torikoshi; Fabian Raudzus; Yukimasa Taniguchi; Susumu Miyamoto; Kiyotoshi Sekiguchi; Jun Takahashi
        Stem cells translational medicine, 23 May 2022
      • Magnetic spatiotemporal control of SOS1 coupled nanoparticles for guided neurite growth in dopaminergic single cells
        Fabian Raudzus; Hendrik Schöneborn; Sebastian Neumann; Emilie Secret; Aude Michel; Jérome Fresnais; Oliver Brylski; Christine Ménager; Jean-Michel Siaugue; Rolf Heumann
        Scientific Reports, 31 Dec. 2020, Lead author
      • Parallelized Manipulation of Adherent Living Cells by Magnetic Nanoparticles-Mediated Forces
        Maud Bongaerts; Koceila Aizel; Emilie Secret; Audric Jan; Tasmin Nahar; Fabian Raudzus; Sebastian Neumann; Neil Telling; Rolf Heumann; Jean-Michel Siaugue; Christine Ménager; Jérôme Fresnais; Catherine Villard; Alicia El Haj; Jacob Piehler; Monte A. Gates; Mathieu Coppey
        International Journal of Molecular Sciences, 08 Sep. 2020
      • Novel tools towards magnetic guidance of neurite growth
        Hendrik Schöneborn; Fabian Raudzus; Otten, Nils; Irmgard Dietzel-Meyer; Heumann, Rolf; Zähres, Holm; Secret, Emilie; Michel, Aude; Fresnais, Jérome; Ménager, Christine; Siaugue, Jean-Michel
        Journal of functional biomaterials, 16 Jul. 2019
      • Lethal factor domain-mediated delivery of Nurr1 transcription factor enhances tyrosine hydroxylase activity and protects from neurotoxin-induced degeneration of dopaminergic cells
        Dennis Paliga; Fabian Raudzus; Heumann, Rolf; Sebastian Neumann; Leppla, Stephen H.
        Molecular neurobiology, May 2019
      • Perspectives of RAS and RHEB GTPase Signaling Pathways in Regenerating Brain Neurons
        Hendrik Schöneborn; Fabian Raudzus; mathieu coppey; Sebastian Neumann; Rolf Heumann
        International Journal of Molecular Sciences, 14 Dec. 2018, Lead author

      Presentations

      • Cell Signaling Modulation for Improved Cell Replacement Therapies in Parkinson’s Disease
        Fabian Raudzus
        Cell Sorting APAC User Meeting 2024, 20 Sep. 2024, Invited
      • RAS Pathway Activation for Enhanced Survival and Neurite Growth of Induced Dopaminergic Neurons
        Fabian Raudzus
        Seminar, Karolinska Institutet, Stockholm, Sweden, 15 Jul. 2024, Invited
      • RAS pathway activation for enhanced survival and neurite growth of induced dopaminergic neurons
        Fabian Raudzus; Karen Kira; Daisuke Doi; Jun Takahashi
        ISSCR 2024 Annual Meeting, Hamburg, Germany, 10 Jul. 2024
      • Optimization of Cell Replacement Therapies in the CNS: Magnetic Nanoparticles and Signaling Pathway Modulation
        Fabian Raudzus
        Seminar, University of Pisa, Italy, 29 Feb. 2024, Invited
      • New approaches from Bochum for optimizing cell replacement therapies in Parkinson's disease in Kyoto
        Fabian Raudzus
        Anniversary Celebration: 30 Years of Biochemistry at RUB, Ruhr-Uni Bochum, Germany, 01 Oct. 2022, Invited
      • Spatiotemporal control of RAS pathway activation by biofunctionalized nanoparticles for guided neurite growth, maturation, and regeneration
        Fabian Raudzus
        Meeting of the GBM Study Group “Molecular Neurobiology“, Ruhr-Uni Bochum, Germany, 29 Sep. 2022, Invited
      • Improving neuronal survival and integration of induced cortical neurons after transplantation by controlled RAS/MEK/ERK-pathway activation
        Fabian Raudzus; Jun Takahashi
      • Novel Tools towards Magnetic Guidance of Neurite Growth in Dopaminergic Cells: Cytoplasmic Capturing and Guidance of Magnetic Nanoparticles Functionalized with Neurite-Promoting RAS Proteins
        Fabian Raudzus, Hendrik Schöneborn, Emilie Secret, Rolf Heumann
        70. Mosbacher Colloquium, GBM Spring Conference, Mosbach, Germany
      • Remote Control of Neuronal Cell Signaling by Cytoplasmic Magnetic Nanoparticles
        Fabian Raudzus; H. Schöneborn; E. Secret; R. Heumann
        Dynamics of the Nervous system in Health and Disease, Meeting of the GBM Study Group „Molecular Neurobiology“, Marburg, Germany,, Invited
      • Cellular Delivery of a Novel Transcription Factor Nurr1 Fusion Protein Enhances Tyrosine Hydroxylase Activity and Protects from Toxic Insults of Dopaminergic Cells
        S. Neumann; D. Paliga; Fabian Raudzus; S. H. Leppla; R. Heumann
        Dynamics of the Nervous system in Health and Disease, Meeting of the GBM Study Group „Molecular Neurobiology“, Marburg, Germany
      • Remote Control of Neuronal Cell Signaling by Cytoplasmic Magnetic Nanoparticles
        Fabian Raudzus; H. Schöneborn; E. Secre; R. Heumann
        Dynamics of the Nervous system in Health and Disease, Meeting of the GBM Study Group „Molecular Neurobiology“, Marburg, Germany
      • Membrane permeable Nurr1 fusion protein promotes protection and programming of dopaminergic
        D. Paliga; S. Neumann; Fabian Raudzus; R. Heumann
        11th FENS Forum, Berlin, Germany
      • Toxin mediated delivery of functional Nurr1 fusion protein as promising tool for programming of dopaminergic cells
        D. Paliga; S. Neumann; Fabian Raudzus; R. Heumann
        Molecular Basis of Life, GBM Fall Conference, Bochum, Germany
      • Remote Control of Cell Signaling Pathways with Magnetic Nanoparticles inside Living Cells
        Fabian Raudzus; H. Schöneborn; R. Heumann
        Molecular Basis of Life, GBM Fall Conference, Bochum, Germany
      • Label Free Quantitative Proteomics of Astrocytes Directly Converted to Neurons
        H. Schöneborn; S. Islam; Fabian Raudzus; C. Rolfes; M. Krüger; H. Heumann; K. Chakrabarty, S
        Göttingen Meeting of the German Neuroscience Society, Göttingen, Germany
      • Analysis of transcription factors designed for protein transduction in neural reprogramming
        S. Neumann; Fabian Raudzus; H. Schöneborn; K. Chakrabarty; R. Heumann
        65. Mosbacher Colloquium, GBM Spring Conference, Mosbach, Germany
      • Functional analysis of dopaminergic reprogramming factors designed for protein transduction in neural reprogramming
        S. Neumann; N. Treuter; D. Paliga; Fabian Raudzus; C. Rolfes; H. Schöneborn; K. Chakrabarty, R; Heumann
        Molecular Life Sciences 2013, International Symposium of the German Society for Biochemistry and Molecular Biology (GBM), Frankfurt am Main, Germany
      • Generation and functional analysis of engineered proteins in neural reprogramming
        S. Neumann; N. Treuter; D. Paliga; Fabian Raudzus; C. Rolfes; H. Schöneborn; K. Chakrabarty; R. Heumann
        7th International Meeting Stem Cell Network NRW, Cologne, Germany

      Media Coverage

      • Magnetic nanoparticles arouse hope for therapies against Parkinson’s disease
        https://www.de24.news/en/2021/01/magnetic-nanoparticles-arouse-hope-for-therapies-against-parkinsons-disease.html, Jan. 2021, Internet
      • Initial steps to show nerves their growth direction magnetically
        https://news.rub.de/english/press-releases/2021-01-18-biochemistry-initial-steps-show-nerves-their-growth-direction-magnetically, Jan. 2021, Internet
      • No return ticket home
        CiRA, CiRA Reporter Vol. 25, https://www.cira.kyoto-u.ac.jp/e/pressrelease/cira-reporter/vol25/#/highlights01, Internet
      • An endogenous protein might become a candidate for drug development
        https://news.rub.de/english/press-releases/2018-08-31-parkinsons-disease-endogenous-protein-might-become-candidate-drug-development, Internet

      External funds: Kakenhi

      • Rewiring the brain: remote-controlled axon guidance by magnetic nanoparticles to improve Parkinson's therapies
        Grant-in-Aid for Scientific Research (C)
        Basic Section 46010:Neuroscience-general-related
        Kyoto University
        Raudzus Fabian
        From 01 Apr. 2022, To 31 Mar. 2025, Granted
        Parkinson's Disease;Magnetic Nanoparticle;Cell Replacment;Stem Cells;Dopaminergic Neurons;Dopaminergic neurons;Stem cells (iPSCs);Magnetic nanoparticles;Halbach magnet;Axon guidance;CNS regeneration;Parkinson's disease;Nanotechnology;Cell Replacement Therapy;Magnetic Nanoparticles;Pluripotent Stem Cells;Neuronal Regeneration
      • International collaboration for the development of new molecular-targeted antimicrobial agents
        Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
        Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
        Kyoto University
        Kim Minsoo
        From 07 Oct. 2022, To 31 Mar. 2026, Granted
        細菌感染;細胞運動;抗菌剤
      list
        Last Updated :2025/05/27

        Education

        Teaching subject(s)

        • From 01 Apr. 2024, To 31 Mar. 2025
          ILAS Seminar-E2
          Z002, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2024, To 31 Mar. 2025
          ILAS Seminar-E2
          Z002, Fall, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2024, To 31 Mar. 2025
          Physiology in Health and Sports-E2
          U165, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2024, To 31 Mar. 2025
          Introduction to Lifestyle Related Diseases-E2
          U106, Fall, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Introduction to Lifestyle Related Diseases-E2
          U106, Fall, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Basics of the Human Body-E2
          U104, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          ILAS Seminar-E2
          Z002, Fall, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          ILAS Seminar-E2
          Z002, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Introduction to Lifestyle Related Diseases-E2
          U106, Fall, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          ILAS Seminar-E2
          Z002, Fall, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Basics of the Human Body-E2
          U104, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          ILAS Seminar-E2
          Z002, Spring, Institute for Liberal Arts and Sciences, 2
        • From Apr. 2021, To Mar. 2022
          Basics of the Human Body-E2
          Spring, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          ILAS Seminar-E2 :Disorders of the Nervous System
          Fall, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          ILAS Seminar-E2 :Physiological Neuroscience
          Spring, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Introduction to Lifestyle Related Diseases-E2
          Fall, 全学共通科目

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