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Goto, Takayuki
Graduate School of Medicine, Medicine Senior Lecturer/ Junior Associate Professor
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Last Updated :2025/04/28
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Last Updated :2025/04/28
Research
External funds: Kakenhi
- 可塑性の制御による固形癌の革新的治療法の開発Grant-in-Aid for Challenging Research (Exploratory)Medium-sized Section 56:Surgery related to the biological and sensory functions and related fieldsNagoya University;Kyoto University赤松 秀輔From 09 Jul. 2021, To 31 Mar. 2024, Granted前立腺癌;神経内分泌前立腺癌;可塑性;神経内分泌化;固形癌
- Establishment of an evaluation model for renal cancer immune niche replication and treatment using next-generation humanized syngeneic mice.Grant-in-Aid for Challenging Research (Exploratory)Medium-sized Section 56:Surgery related to the biological and sensory functions and related fieldsKyoto UniversityOsamu OgawaFrom 30 Jul. 2020, To 31 Mar. 2023, Project Closed免疫チェックポイント阻害剤;腎細胞癌;ヒト化シンジェニックマウス;患者由来ゼノグラフト;抗PD-1抗体;エクソソーム;患者癌組織由来ゼノグラフト;薬剤抵抗性;転移形成;腫瘍間質相互作用;腎癌;癌免疫;癌ニッチ;ゼノグラフト;シンジェニックマウス
- Drug screening using xenografts and organoids derived from castration-resistant prostate cancer patients.Grant-in-Aid for Early-Career ScientistsBasic Section 56030:Urology-relatedKyoto UniversityTakayuki GotoFrom 01 Apr. 2019, To 31 Mar. 2022, Project Closed去勢抵抗性前立腺癌;ゼノグラフト;オルガノイド;ドラッグスクリーニング;前立腺癌;創薬;去勢抵抗性;化合物スクリーニング
- Elucidation of the bladder clock function using flavonoids and its application for timed therapy in nocturia patientsGrant-in-Aid for Scientific Research (C)Basic Section 56030:Urology-relatedDepartment of Clinical Research, National Hospital Organization Kyoto Medical CenterHaruki ITOFrom 01 Apr. 2018, To 31 Mar. 2023, Project Closed夜間頻尿;時計遺伝子;ノビレチン;フラボノイド系化合物;概日リズム
- Investigation of novel prostate cancer diagnosis and treatment methods focusing lipid metabolismGrant-in-Aid for Scientific Research (B)Basic Section 56030:Urology-relatedMie University;Kyoto UniversityTakahiro InoueFrom 01 Apr. 2018, To 31 Mar. 2021, Project Closed脂質;前立腺癌;尿;脂質過酸化反応;質量分析;尿中揮発性有機化合物
- Elucidation of the mechanism of resistance to new generation androgen receptor axis-targeted agents by using various patient-derived xenografts of prostate cancerGrant-in-Aid for Research Activity Start-upKyoto UniversityTAKAYUKI GOTOFrom 25 Aug. 2017, To 31 Mar. 2019, Project Closed去勢抵抗性前立腺癌;xenograft;エンザルタミド抵抗性;前立腺癌;去勢抵抗性;癌;プロテオミクス;治療抵抗性;バイオマーカー;PDXモデル;エンザルタミド;多様性
- 患者由来ゼノグラフトを用いたCDK12変異前立腺癌のPARP阻害薬不応性の克服Grant-in-Aid for Scientific Research (C)Basic Section 56030:Urology-relatedKyoto University後藤 崇之From 01 Apr. 2022, To 31 Mar. 2025, GrantedCDK12異常前立腺癌;去勢抵抗性前立腺癌;ATM阻害薬;PARP阻害薬;PDX;前立腺癌;CDK12;相同組換え修復関連遺伝子;患者由来ゼノグラフト
- 炎症性膀胱疾患における慢性炎症と尿路上皮ギャップ結合蛋白の関与の解明Grant-in-Aid for Scientific Research (C)Basic Section 56030:Urology-relatedKyoto University河野 仁From 01 Apr. 2022, To 31 Mar. 2025, Grantedシクロホスファミド;ノビレチン;コネキシン43;尿路上皮;間質性膀胱炎;Cx43
- Establishment of a novel therapeutic strategy for progressive urogenital carcinoma focusing on the preferential metastasis mechanismGrant-in-Aid for Scientific Research (C)Basic Section 56030:Urology-relatedNational Cancer Center Japan松井 喜之From 01 Apr. 2024, To 31 Mar. 2027, Granted尿路性器癌;臓器特異的転移指向性
- 去勢抵抗性前立腺癌のPARP阻害薬不応性に対する高用量アンドロゲン併用治療の開発Grant-in-Aid for Scientific Research (C)Basic Section 56030:Urology-relatedKyoto University砂田 拓郎From 01 Apr. 2024, To 31 Mar. 2027, Granted去勢抵抗性前立腺癌
- Establishment of genomic pathology based tumor subtyping system for solid cancers by single cell spatial transcriptome sequencingGrant-in-Aid for Challenging Research (Exploratory)Medium-sized Section 56:Surgery related to the biological and sensory functions and related fieldsNagoya University赤松 秀輔From 28 Jun. 2024, To 31 Mar. 2027, Granted前立腺癌;単一細胞遺伝子発現解析;空間遺伝子発現解析
