Genetic Landscape of Multistep Hepatocarcinogenesis.
Haruhiko Takeda; Atsushi Takai; Yuji Eso; Ken Takahashi; Hiroyuki Marusawa; Hiroshi Seno
Cancers, 2022年01月23日
Pretreatment Neutrophil-to-Lymphocyte Ratio as a Predictive Marker of Response to Atezolizumab Plus Bevacizumab for Hepatocellular Carcinoma.
Yuji Eso; Haruhiko Takeda; Kojiro Taura; Atsushi Takai; Ken Takahashi; Hiroshi Seno
Current oncology (Toronto, Ont.), 2021年10月14日
Author Correction: DNA methyltransferase 3B plays a protective role against hepatocarcinogenesis caused by chronic inflammation via maintaining mitochondrial homeostasis.
Eriko Iguchi; Atsushi Takai; Haruhiko Takeda; Ken Kumagai; Soichi Arasawa; Yuji Eso; Takahiro Shimizu; Yoshihide Ueda; Hiroyuki Marusawa; Hiroshi Seno
Scientific reports, 2021年07月01日
A simplified method to quantitatively predict the effect of lenvatinib on hepatocellular carcinoma using contrast-enhanced ultrasound with perfluorobutane microbubbles
Yuji Eso; Shigeharu Nakano; Masako Mishima; Soichi Arasawa; Eriko Iguchi; Haruhiko Takeda; Atsushi Takai; Ken Takahashi; Hiroshi Seno
Quantitative Imaging in Medicine and Surgery, 2021年06月, 査読有り
DNA methyltransferase 3B plays a protective role against hepatocarcinogenesis caused by chronic inflammation via maintaining mitochondrial homeostasis.
Eriko Iguchi; Atsushi Takai; Haruhiko Takeda; Ken Kumagai; Soichi Arasawa; Yuji Eso; Takahiro Shimizu; Yoshihide Ueda; Hiroyuki Marusawa; Hiroshi Seno
Scientific reports, 2020年12月04日
Hes1 Is Essential in Proliferating Ductal Cell-Mediated Development of Intrahepatic Cholangiocarcinoma.
Branched-chain amino acid to tyrosine ratio is an essential pre-treatment factor for maintaining sufficient treatment intensity of lenvatinib in patients with hepatocellular carcinoma.
Yuji Eso; Shigeharu Nakano; Masako Mishima; Soichi Arasawa; Eriko Iguchi; Haruhiko Takeda; Atsushi Takai; Ken Takahashi; Hiroshi Seno
Journal of hepato-biliary-pancreatic sciences, 2020年12月, 査読有り
Multiregional whole‐genome sequencing of hepatocellular carcinoma with nodule‐in‐nodule appearance reveals stepwise cancer evolution
Single-molecular real-time deep sequencing reveals the dynamics of multi-drug resistant haplotypes and structural variations in the hepatitis C virus genome.
Utility of ultrasound-guided liver tumor biopsy for next-generation sequencing-based clinical sequencing.
Yuji Eso; Tadayuki Kou; Hiroki Nagai; Young Hak Kim; Masashi Kanai; Shigemi Matsumoto; Masako Mishima; Soichi Arasawa; Eriko Iguchi; Fumiyasu Nakamura; Haruhiko Takeda; Atsushi Takai; Ken Takahashi; Yoshihide Ueda; Manabu Muto; Hiroshi Seno
Hepatology research : the official journal of the Japan Society of Hepatology, 2019年05月, 査読有り
Genome-wide RNAi Screen identifies PMPCB as a therapeutic vulnerability in EpCAM+ hepatocellular carcinoma.
Takai A; Dang H; Oishi N; Khatib S; Martin SP; Dominguez DA; Luo J; Bagni R; Wu X; Powell K; Ye QH; Jia H; Qin LX; Chen J; Mitchell GA; Luo X; Thorgeirsson SS; Wang XW
Cancer Research, 2019年05月, 査読有り
がんゲノム医療における肝生検の役割
恵荘 裕嗣; 高井 淳; 高橋 健; 上田 佳秀; 妹尾 浩
肝臓, 2019年04月
Post SVR時代のC型肝炎診療 Special Populationに対するDAA治療 肝移植後症例に対する治療成績
上田佳秀; 恵荘裕嗣; 高井淳; 高橋健; 妹尾浩
肝胆膵, 2019年04月, 査読有り
Combination of Mac-2 Binding Protein Glycosylation Isomer and Up-To-Seven Criteria as a Useful Predictor for Child-Pugh Grade Deterioration after Transarterial Chemoembolization for Hepatocellular Carcinoma.
Yuji Eso; Atsushi Takai; Ken Takahashi; Yoshihide Ueda; Kojiro Taura; Hiroyuki Marusawa; Hiroshi Seno
Sulfatase 2-TGFβ1-SMADシグナル伝達によるPeriostinの誘導が肝細胞癌において血管新生に寄与する(Induction of Periostin by Sulfatase 2-TGFβ1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma)
井口 恵里子; 高井 淳; 上田 佳秀; 妹尾 浩
日本癌学会総会記事, 2018年09月
Association of Mac-2-binding protein glycosylation isomer level with nutritional status in chronic liver disease.
Yuji Eso; Atsushi Takai; Kojiro Taura; Ken Takahashi; Yoshihide Ueda; Hiroyuki Marusawa; Hiroshi Seno
Journal of gastroenterology and hepatology, 2018年02月22日, 査読有り
Proliferating EpCAM-Positive Ductal Cells in the Inflamed Liver Give Rise to Hepatocellular Carcinoma
Hepatobiliary and Pancreatic: Granulomatous hepatitis due to disseminated bacillus Calmette-Guérin disease.
Eso Y; Takai A; Arasawa S; Ueda Y; Seno H
Journal of Gastroenterology and Hepatology, 2017年09月, 査読有り
Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma
Hien Dang; Atsushi Takai; Marshonna Forgues; Yotsowat Pomyen; Haiwei Mou; Wen Xue; Debashish Ray; Kevin C. H. Ha; Quaid D. Morris; Timothy R. Hughes; Xin Wei Wang
Three-dimensional Organotypic Culture Models of Human Hepatocellular Carcinoma
Atsushi Takai; Valerie Fako; Hien Dang; Marshonna Forgues; Zhipeng Yu; Anuradha Budhu; Xin Wei Wang
SCIENTIFIC REPORTS, 2016年02月, 査読有り
Integrative genomics identifies YY1AP1 as an oncogenic driver in EpCAM(+) AFP(+) hepatocellular carcinoma
X. Zhao; S. Parpart; A. Takai; S. Roessler; A. Budhu; Z. Yu; M. Blank; Y. E. Zhang; H-L Jia; Q-H Ye; L-X Qin; Z-Y Tang; S. S. Thorgeirsson; X. W. Wang
ONCOGENE, 2015年09月, 査読有り
Hepatic stellate cell and monocyte interaction contributes to poor prognosis in hepatocellular carcinoma
Juling Ji; Tobias Eggert; Anuradha Budhu; Marshonna Forgues; Atsushi Takai; Hien Dang; Qinghai Ye; Ju-Seog Lee; Ji Hoon Kim; Tim F. Greten; Xin Wei Wang
HEPATOLOGY, 2015年08月, 査読有り
Exploring the Mechanisms of Gastrointestinal Cancer Development Using Deep Sequencing Analysis
[Genetic alterations leading to the development of colitis-associated colorectal cancers].
Marusawa H; Takai A; Chiba T
Nihon rinsho. Japanese journal of clinical medicine, 2012年02月, 査読有り
Molecular mechanism of colitis-associated colorectal carcinogenesis.
Marusawa H; Endo Y; Takai A; Chiba T
Inflammation and Regeneration, 2012年, 査読有り, 招待有り
[The cutting-edge of medicine; inflammation and development of gastrointestinal cancers].
Chiba T; Marusawa H; Matsumoto Y; Takai A
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2011年08月, 査読有り
Acquisition of genetic aberrations by activation-induced cytidine deaminase (AID) during inflammation-associated carcinogenesis
Atsushi Takai; Hiroyuki Marusawa; Tsutomu Chiba
Cancers, 2011年06月, 査読有り, 招待有り
Role of Activation-Induced Cytidine Deaminase in Inflammation-Associated Cancer Development
Hiroyuki Marusawa; Atsushi Takai; Tsutomu Chiba
ADVANCES IN IMMUNOLOGY, VOL 111, 2011年, 査読有り, 招待有り
Pancreatic somatostatinoma with von Recklinghausen’s disease.
Takai A; Setoyama T; Miyamoto S
Clinical Gastroenterology and Hepatology, 2009年05月, 査読有り
A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations
A. Takai; T. Toyoshima; M. Uemura; Y. Kitawaki; H. Marusawa; H. Hiai; S. Yamada; I. M. Okazaki; T. Honjo; T. Chiba; K. Kinoshita
ONCOGENE, 2009年01月, 査読有り
遺伝子編集酵素AIDを用いた新しい肝発癌マウスモデルの作成(A novel mouse model of hepatocarcinogenesis triggered by activation-induced cytidine deaminase (AID))
高井 淳; 丸澤 宏之; 日合 弘; 千葉 勉; 木下 和生
日本癌学会総会記事, 2008年09月
A case of ruptured gastroduodenal arterial pseudoaneurysm with penetration to the duodenum, successfully treated with transcatheter arterial embolization