Preliminary study of a compact epithermal neutron absolute flux intensity measurement system for real-time in-vivo dose monitoring in boron neutron capture therapy
Evaluation of dose calculation method with a combination of Monte Carlo method and removal-diffusion equation in heterogeneous geometry for boron neutron capture therapy.
Clinical evaluation of performance, stability, and longevity of an accelerator system designed for boron neutron capture therapy utilising a beryllium target.
Naonori Hu; Ryo Kakino; Akinori Sasaki; Syuushi Yoshikawa; Kazuhiko Akita; Satoshi Takeno; Yuki Yoshino; Teruhito Aihara; Keiji Nihei; Mai Nojiri; Nishiki Matsubayashi; Takushi Takata; Hiroki Tanaka; Minoru Suzuki; Koji Ono
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2024年12月
Characterization of acrylic phantom for use in quality assurance of BNCT beam output procedure.
Nonclinical pharmacodynamics of boron neutron capture therapy using direct intratumoral administration of a folate receptor targeting novel boron carrier.
Developing and validating measurement methods combining 6LiF sintered capsule and Mg2SiO4: Tb (TLD-MSO-S) for -ray dose evaluation at accelerator-based BNCT system
Development of a prompt gamma-ray detector with an 8 × 8 array LaBr 3(Ce) scintillator and a multi-pixel photon counter for boron neutron capture therapy
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2023年10月
First optical observation of B-10-neutron capture reactions using a boron-added liquid scintillator for quality assurance in boron neutron capture therapy
Multi-Targeted Neutron Capture Therapy Combined with an 18 kDa Translocator Protein-Targeted Boron Compound Is an Effective Strategy in a Rat Brain Tumor Model.
The impact of TP53 status of tumor cells including the type and the concentration of administered 10B delivery agents on compound biological effectiveness in boron neutron capture therapy.
Shin-Ichiro Masunaga; Yu Sanada; Takushi Takata; Hiroki Tanaka; Yoshinori Sakurai; Minoru Suzuki; Mitsunori Kirihata; Koji Ono
Journal of radiation research, 2023年02月10日
γ-Ray measurements in boron neutron capture therapy using BeO ceramic thermoluminescence dosimeter
Measurement of spatial fluence distribution of neutrons and gamma rays using MAGAT-type gel detector doped with LiCl for BNCT at Kyoto University Reactor
International journal of radiation biology, 2021年07月26日
Improving the spatial resolution of a pixelated LaBr3(Ce) scintillator coupled with a multi-pixel photon counter array for boron neutron capture therapy
Evaluation of the energy resolution of a prompt gamma-ray imaging detector using LaBr3(Ce) scintillator and 8 × 8 array MPPC for an animal study of BNCT
Evaluation of PHITS for microdosimetry in BNCT to support radiobiological research
N. Hu; H. Tanaka; T. Takata; S. Endo; S. Masunaga; M. Suzuki; Y. Sakurai
Applied Radiation and Isotopes, 2020年07月, 査読有り
An attempt to improve the therapeutic effect of boron neutron capture therapy using commonly employed 10B-carriers based on analytical studies on the correlation among quiescent tumor cell characteristics, tumor heterogeneity and cancer stemness.
Shin-Ichiro Masunaga; Yu Sanada; Keizo Tano; Yoshinori Sakurai; Hiroki Tanaka; Takushi Takata; Minoru Suzuki; Koji Ono
Journal of radiation research, 2020年06月30日, 査読有り
Microdosimetric quantities of an accelerator-based neutron source used for boron neutron capture therapy measured using a gas-filled proportional counter.
Usefulness of combination with both continuous administration of hypoxic cytotoxin and mild temperature hyperthermia in boron neutron capture therapy in terms of local tumor response and lung metastatic potential.
Shin-Ichiro Masunaga; Yoshinori Sakurai; Hiroki Tanaka; Takushi Takata; Minoru Suzuki; Yu Sanada; Keizo Tano; Akira Maruhashi; Koji Ono
International journal of radiation biology, 2019年12月, 査読有り
Development of a real-time neutron detector for measurement at whole body position in BNCT
H. Tanaka; T. Takata; M. Sato; N. Matsubayashi; K. Okazaki; N. Hu; S. Kawabata; Y. Sakurai; S. Masunaga; M. Suzuki
2019 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2019, 2019年10月
Biological characteristics of gene expression features in pancreatic cancer cells induced by proton and X-ray irradiation.
Radiation and environmental biophysics, 2019年03月, 査読有り
Influence of field-of-view and section thickness of diagnostic imaging on thermal neutron flux estimation in dose-planning for boron neutron capture therapy.
Sato H; Takata T; Sakurai Y
Radiological physics and technology, 2018年12月, 査読有り
Development of real-time thermal neutron monitor array for boron neutron capture therapy
Tanaka H; Takata T; Sakurai Y; Kawabata S; Suzuki M; Masunaga S; Ono K
Ther Radiol Oncol, 2018年10月, 査読有り
ELUCIDATION OF PHOSPHOLIPID ALTERATION IN BRAIN AFTER IRRADIATION USING BRAIN RADIATION NECROSIS MOUSE MODEL
Improvement of depth dose distribution using multiple-field irradiation in boron neutron capture therapy
N. Fujimoto; H. Tanaka; Y. Sakurai; T. Takata; N. Kondo; M. Narabayashi; Y. Nakagawa; T. Watanabe; Y. Kinashi; S. Masunaga; A. Maruhashi; K. Ono; M. Suzuki
APPLIED RADIATION AND ISOTOPES, 2015年12月
Localized radiation necrosis model in mouse brain using proton ion beams
Characterization of neutrons from a thick target Be-9(p, n) reaction by multiple foil activation technique for practical applications: measurement of integral cross sections and their comparison with integrated data from data files
A development of optimized radiation shielding design method for contaminated soil in Fukushima (The 12th International Conference on Radiation Shielding (ICRS-12) and the 17th Topical Meeting of the Radiation Protection and Shielding Division of ANS (RPS
Kimura Ken-ichi; Suzuki Yusuke; Takata Takushi
Progress in nuclear science and technology, 2014年04月, 査読有り
Development of a real-time dosimeter for boron neutron capture therapy
Improvement of dose distribution in phantom by using epithermal neutron source based on the Be(p,n) reaction using a 30 MeV proton cyclotron accelerator
H. Tanaka; Y. Sakurai; M. Suzuki; T. Takata; S. Masunaga; Y. Kinashi; G. Kashino; Y. Liu; T. Mitsumoto; S. Yajima; H. Tsutsui; M. Takada; A. Maruhashi; K. Ono
Radio-Sensitivity of Pimonidazole -Unlabeled Intratumor Quiescent Cells to γ-Rays, Accelerated Carbon Ion Beams and Boron Neutron Capture Reaction (BNCR)
Masunaga S; Sakurai Y; Tanaka H; Hirayama R; Matsumoto Y; Uzawa A; Tano K; Sanada Y; Suzuki M; Kondo N; Takata T; Watanabe T; Tamari Y; Maruhashi A; Ono K
9th Young Researchers' BNCT Meeting, 2017年11月
LIPID ALTERATION FOLLOWING PROTON BEAM IRRADIATION IN MOUSE BRAIN OF RADIATION NECROSIS MODEL
N. Kondo; K. Nakayama; Y. Sakurai; T. Takata; K. Kume; S. Miyatake; T. Inoue; O. Ogawa; M. Suzuki
Effect of oxygen pressure during incubation with a 10B-carrier on 10B uptake capacity of cultured p53 wild-type and mutated tumor cells with reference to dependency on p53 status of tumor cells and types of 10B-carriers
Masunaga S; Tatebe H; Nishimura Y; Tano K; Sanada Y; Sakurai Y; Tanaka H; Suzuki M; Kondo N; Watanabe T; Takata T; Fujimoto N; Maruhashi A; Ono K
17th International Congress on Neutron Capture Therapy, 2016年04月, 査読有り
Study on the extended collimator for Cyclotron-Based Epithermal Neutron Source (C-BENS)
H. Tanaka; Y. Sakurai; T. Takata; N. Fujimoto; M. Suzuki; S. Masunaga; T. Mitsumoto; A. Maruhashi; K. Ono
8th Young Researchers BNCT Meeting, 2015年09月
Radiation necrosis model in mouse brain following dose escalation
N. Kondo; Y. Sakurai; T. Takata; Y. Nakagawa; H. Tanaka; T. Watanabe; K. Kume; N. Takai; S. Miyatake; S. Masunaga; M. Suzuki; K. Ono
8th Young Researchers BNCT Meeting, 2015年09月
Estimation method for influence of patient position error in BNCT irradiation: a conceptual study
T. Takata; N. Fujimoto; H. Tanaka; Y. Sakurai; M. Suzuki
8th Young Researchers BNCT Meeting, 2015年09月
A study on improvement of dose distribution using bolus in BNCT for head and neck tumors
Y. Sakurai; H. Tanaka; T. Takata; N. Fujimoto; N. Kondo; Y. Nakagawa; T. Watanabe; M. Narabayashi; Y. Kinashi; S. Masunaga; M. Suzuki; K. Ono; A. Maruhashi
8th Young Researchers BNCT Meeting, 2015年09月
A study on improvement method of dose distribution using bolus in boron neutron capture therapy for head and neck tumors