Journal of the American Chemical Society, 2025年01月06日, 査読有り
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
Paras S Minhas; Jeffrey R Jones; Amira Latif-Hernandez; Yuki Sugiura; Aarooran S Durairaj; Takeshi Uenaka; Qian Wang; Siddhita D Mhatre; Ling Liu; Travis Conley; Hannah Ennerfelt; Yoo Jin Jung; Praveena Prasad; Brenita C Jenkins; Ryan Goodman; Traci Newmeyer; Kelly Heard; Austin Kang; Edward N Wilson; Erik M Ullian; Geidy E Serrano; Thomas G Beach; Joshua D Rabinowitz; Marius Wernig; Makoto Suematsu; Frank M Longo; Melanie R McReynolds; Fred H Gage; Katrin I Andreasson
bioRxiv : the preprint server for biology, 2024年06月28日
Chemogenetic activation of hepatic G12 signaling ameliorates hepatic steatosis and obesity.
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
Paras S Minhas; Jeffrey R Jones; Amira Latif-Hernandez; Yuki Sugiura; Aarooran S Durairaj; Qian Wang; Siddhita D Mhatre; Takeshi Uenaka; Joshua Crapser; Travis Conley; Hannah Ennerfelt; Yoo Jin Jung; Ling Liu; Praveena Prasad; Brenita C Jenkins; Yeonglong Albert Ay; Matthew Matrongolo; Ryan Goodman; Traci Newmeyer; Kelly Heard; Austin Kang; Edward N Wilson; Tao Yang; Erik M Ullian; Geidy E Serrano; Thomas G Beach; Marius Wernig; Joshua D Rabinowitz; Makoto Suematsu; Frank M Longo; Melanie R McReynolds; Fred H Gage; Katrin I Andreasson
Science (New York, N.Y.), 2024年08月23日, 査読有り
Cysteine depletion triggers adipose tissue thermogenesis and weight-loss.
Aileen H Lee; Lucie Orliaguet; Yun-Hee Youm; Rae Maeda; Tamara Dlugos; Yuanjiu Lei; Daniel Coman; Irina Shchukina; Sairam Andhey; Steven R Smith; Eric Ravussin; Krisztian Stadler; Fahmeed Hyder; Maxim N Artyomov; Yuki Sugiura; Vishwa Deep Dixit
bioRxiv : the preprint server for biology, 2024年08月08日
PTBP1 protects Y RNA from cleavage leading to its apoptosis-specific degradation.
Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species.
Shun-Ichi Yamashita; Yuki Sugiura; Yuta Matsuoka; Rae Maeda; Keiichi Inoue; Kentaro Furukawa; Tomoyuki Fukuda; David C Chan; Tomotake Kanki
Cell death and differentiation, 2024年03月22日, 査読有り
Determination of three C18-oxygenated steroids in adrenal lesion segments in primary aldosteronism by super-selective adrenal venous sampling and LC/ESI-MS/MS.
Differential cardiomyocyte transcriptomic remodeling during in vitro Trypanosoma cruzi infection using laboratory strains provides implications on pathogenic host responses
[WITHDRAWN] Activation of transsulfuration pathway to maintain cysteine is a thermogenic checkpoint for the conservation of energy.
Aileen H Lee; Yuki Sugiura; Yun-Hee Youm; Tamara Dlugos; Rae Maeda; Daniel Coman; Olga Spadaro; Sviatoslav Sidorov; Irina Shchukina; Sairam Andhey; Steven R Smith; Eric Ravussin; Fahmeed Hyder; Maxim N Artyomov; Vishwa Deep Dixit
Research square, 2023年06月30日, 査読有り
Cellular senescence induction leads to progressive cell death via the INK4a-RB pathway in naked mole-rats.
A method for determination of aldosterone concentrations of six adrenal venous serum samples during a single LC/ESI-MS/MS run using a sextet of Girard reagents.
Cytologic features of oral squamous cell carcinoma in an Indo‐Pacific bottlenose dolphin ( Tursiops aduncus ): Papanicolaou stain and immunocytochemistry using liquid‐based cytology
What Do We See in Spectra?: Assignment of High-Intensity Peaks of Cutibacterium and Staphylococcus Spectra of MALDI-TOF Mass Spectrometry by Interspecies Comparative Proteogenomics.
Restoring metabolism of myeloid cells reverses cognitive decline in ageing.
Paras S Minhas; Amira Latif-Hernandez; Melanie R McReynolds; Aarooran S Durairaj; Qian Wang; Amanda Rubin; Amit U Joshi; Joy Q He; Esha Gauba; Ling Liu; Congcong Wang; Miles Linde; Yuki Sugiura; Peter K Moon; Ravi Majeti; Makoto Suematsu; Daria Mochly-Rosen; Irving L Weissman; Frank M Longo; Joshua D Rabinowitz; Katrin I Andreasson
Nature, 2021年02月, 査読有り
Distribution of inhaled volatile β-caryophyllene and dynamic changes of liver metabolites in mice.
Immunohistochemistry for aldosterone synthase CYP11B2 and matrix-assisted laser desorption ionization imaging mass spectrometry for in-situ aldosterone detection.
A method for determination of aldosterone in adrenal tributary venous serum by derivatization using Girard P reagent isotopologues followed by LC/ESI-MS/MS.
MP03-05 IMAGING MASS SPECTROMETRY REVEALS CO-ACCUMULATION OF ALDOSTERONE AND 18-OXOCORTISOL WITH CYP11B2 IN PRE-ADENOMATOUS STATES OF PRIMARY ALDOSTERONISM
Analytical and bioanalytical chemistry, 2018年02月, 査読有り
Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system
HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.
Hiroaki Semba; Norihiko Takeda; Takayuki Isagawa; Yuki Sugiura; Kurara Honda; Masaki Wake; Hidenobu Miyazawa; Yoshifumi Yamaguchi; Masayuki Miura; Dana M R Jenkins; Hyunsung Choi; Jung-Whan Kim; Masataka Asagiri; Andrew S Cowburn; Hajime Abe; Katsura Soma; Katsuhiro Koyama; Manami Katoh; Keimon Sayama; Nobuhito Goda; Randall S Johnson; Ichiro Manabe; Ryozo Nagai; Issei Komuro
Nature communications, 2016年05月18日, 査読有り
A Measurement of the Calorimeter Response to Single Hadrons and Determination of the Jet Energy Scale Uncertainty Using LHC Run-1 PP-Collision Data with the ATLAS Detector
H Semba; N Takeda; T Isagawa; Y Sugiura; K Honda; M Wake; H Miyazawa; Dana MR Jenkins; Hyunsung Choi; Jung-whan Kim
Nature Publishing Group, 2016年05月, 査読有り
Detection and molecular characterization of Cryptosporidium and Eimeria species in Philippine bats.
Fumi Murakoshi; Frances C Recuenco; Tsutomu Omatsu; Kaori Sano; Satoshi Taniguchi; Joseph S Masangkay; Philip Alviola; Eduardo Eres; Edison Cosico; James Alvarez; Yumi Une; Shigeru Kyuwa; Yuki Sugiura; Kentaro Kato
Parasitology research, 2016年05月, 査読有り
Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.
Analytical and bioanalytical chemistry, 2015年10月, 査読有り
Therapeutic hypothermia achieves neuroprotection via a decrease in acetylcholine with a concurrent increase in carnitine in the neonatal hypoxia-ischemia.
Microscopic imaging mass spectrometry assisted by on-tissue chemical derivatization for visualizing multiple amino acids in human colon cancer xenografts.
Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis.
Zhongbin Bai; Linjun Cai; Eiji Umemoto; Akira Takeda; Kazuo Tohya; Yutaka Komai; Punniyakoti Thanikachalam Veeraveedu; Erina Hata; Yuki Sugiura; Akiko Kubo; Makoto Suematsu; Haruko Hayasaka; Shinichi Okudaira; Junken Aoki; Toshiyuki Tanaka; Harald M H G Albers; Huib Ovaa; Masayuki Miyasaka
Journal of immunology (Baltimore, Md. : 1950), 2013年03月01日, 査読有り
The Alarmin IL-33 Derived from HSV-2-Infected Keratinocytes Triggers Mast Cell-Mediated Antiviral Innate Immunity
K Nelms; AD Keegan; J Zamorano; JJ Ryan; N Nieuwenhuizen; DR Herbert; F Brombacher; PD Pigatto; A Legori; AS Bigardi; U Sivaprasad; MR Warrier; AM Gibson; T Tazawa; H Sugiura; Y Sugiura; M Rela Uehara; Z Zhao; F Huo; J Jeffry; L Hampton; S Demehri
The Journal of clinical investigation, 2013年, 査読有り
Production and characterization of humic-like substances from pyrolyzed plant materials by chemical oxidation
Analytical and bioanalytical chemistry, 2012年06月, 査読有り
Visualization of acetylcholine distribution in central nervous system tissue sections by tandem imaging mass spectrometry.
Yuki Sugiura; Nobuhiro Zaima; Mitsutoshi Setou; Seiji Ito; Ikuko Yao
Analytical and bioanalytical chemistry, 2012年06月, 査読有り, 筆頭著者
Imaging Mass Spectrometry (IMS) for Biological Application
Yuki Sugiura; Ikuko Yao; Mitsutoshi Setou
Mass Spectrometry Handbook, 2012年05月21日, 査読有り, 筆頭著者
Nanoparticle-assisted laser desorption/ionization (nano-PALDI)-based imaging mass spectrometry (IMS) and its application to brain sciences
Saira Hameed; Yuki Sugiura; Yoshishige Kimura; K Shrivas; Mitsutoshi Setou
Nanomedicine and the nervous system. Science Publishers, Boca Raton, 2012年03月, 査読有り
Axonal gradient of arachidonic acid-containing phosphatidylcholine and its dependence on actin dynamics.
Hyun-Jeong Yang; Yuki Sugiura; Koji Ikegami; Yoshiyuki Konishi; Mitsutoshi Setou
The Journal of biological chemistry, 2012年02月17日, 査読有り
Hydroxylated and non-hydroxylated sulfatide are distinctly distributed in the human cerebral cortex
D. Yuki; Y. Sugiura; N. Zaima; H. Akatsu; Y. Hashizume; T. Yamamoto; M. Fujiwara; K. Sugiyama; M. Setou
Neuroscience, 2011年10月, 査読有り
Method for simultaneous imaging of endogenous low molecular weight metabolites in mouse brain using TiO2 nanoparticles in nanoparticle-assisted laser desorption/ionization-imaging mass spectrometry.
Neuroaxonal dystrophy in calcium-independent phospholipase A2β deficiency results from insufficient remodeling and degeneration of mitochondrial and presynaptic membranes.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011年08月03日, 査読有り
Pathomechanism of neuroaxonal dystrophy in calcium-independent phospholipase A2β knockout mice: O-1-A8
G Beck; H Sumi; Y Sugiura; K Shinzawa; S Kato; M Setou; Y Tsujimoto; S Sakoda
Neuropathology, 2011年06月, 査読有り
Abnormal phospholipids distribution in the prefrontal cortex from a patient with schizophrenia revealed by matrix-assisted laser desorption/ionization imaging mass spectrometry.
Analytical and bioanalytical chemistry, 2011年06月, 査読有り
Visualization of phosphatidylcholine, lysophosphatidylcholine and sphingomyelin in mouse tongue body by matrix-assisted laser desorption/ionization imaging mass spectrometry.
Detection of characteristic distributions of phospholipid head groups and fatty acids on neurite surface by time-of-flight secondary ion mass spectrometry.
Layer-specific sulfatide localization in rat hippocampus middle molecular layer is revealed by nanoparticle-assisted laser desorption/ionization imaging mass spectrometry.
Recombinant mammalian tubulin polyglutamylase TTLL7 performs both initiation and elongation of polyglutamylation on beta-tubulin through a random sequential pathway.
Current Imaging Mass Spectrometry for Metabolite Molecules
Sugiuya Yuki; Setou Mitsutoshi
Mass spectroscopy, 2009年, 筆頭著者
Analysis of a ubiquitin ligase SCRAPPER with imaging mass spectrometry
Ikuko Yao; Yuki Sugiura; Mitsutoshi Setou
Neuroscience Research, 2009年01月
Magnetic nanoparticle-based mass spectrometry for the detection of biomolecules in cultured cells.
Shinji Moritake; Shu Taira; Yuki Sugiura; Mitsutoshi Setou; Yuko Ichiyanagi
Journal of nanoscience and nanotechnology, 2009年01月, 査読有り
Protein denaturation improves enzymatic digestion efficiency for direct tissue analysis using mass spectrometry
M. Setou; T. Hayasaka; S. Shimma; Y. Sugiura; M. Matsumoto
Applied Surface Science, 2008年12月
Matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight (MALDI-QIT-TOF)-based imaging mass spectrometry reveals a layered distribution of phospholipid molecular species in the mouse retina.
Rapid communications in mass spectrometry : RCM, 2008年11月, 査読有り
Imaging Mass Spectrometry Technology and Application on Ganglioside Study; Visualization of Age-Dependent Accumulation of C20-Ganglioside Molecular Species in the Mouse Hippocampus
High-sensitivity analysis of glycosphingolipids by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight imaging mass spectrometry on transfer membranes.
脂質とステロイドのin vivoでの機能 無脊椎動物モデル生体からのアプローチ イメージング質量分析(IMS) C.elegansにおける脂質の空間的分布を可視化する新しいイメージングツール(Functions of lipids and steroids in vivo: approaches from invertebrate model organisms Imaging mass spectrometry (IMS): A novel imaging tool to visualize the spatial distribution of lipids in C. elegans)
木村 芳滋; 杉浦 悠毅; 早坂 孝宏; 瀬藤 光利
日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 2010年12月
ニューロンにおける多価不飽和脂肪酸含有ホスファチジルコリンの軸勾配(Axonal Gradient of Poly Unsaturated Fatty Acid-containing Phosphatidylcholines in Neurons)
マトリクス支援レーザー破壊/イオン化飛行時間質量分析法を用いた副腎組織における副腎皮質ホルモンの可視化(Visualization of adrenocortical hormone in adrenal tissues by matrix assisted laser desorption/ionization and time of flight mass spectrometry)
Visualizing the distribution of metabolites and the efficacy of BIBF1120 on metabolic status of lung cancer derived tumors by imaging mass-spectrometry (MS)
Sulfatide accumulation in the dystrophic terminals of gracile axonal dystrophy mice : lipid analysis using matrix-assisted laser desorption/ionization imaging mass spectrometry
マトリクス支援レーザー破壊/イオン化飛行時間質量分析法を用いた副腎組織における副腎皮質ホルモンの可視化(Visualization of adrenocortical hormone in adrenal tissues by matrix assisted laser desorption/ionization and time of flight mass spectrometry)
脂質とステロイドのin vivoでの機能 無脊椎動物モデル生体からのアプローチ イメージング質量分析(IMS) C.elegansにおける脂質の空間的分布を可視化する新しいイメージングツール(Functions of lipids and steroids in vivo: approaches from invertebrate model organisms Imaging mass spectrometry (IMS): A novel imaging tool to visualize the spatial distribution of lipids in C. elegans)
Effective Sample Preparations in Imaging Mass Spectrometry (Mass Spectrometry) -- (Special Issue : 4th Asia and Oceania Mass Spectrometry Conference (AOMSC))