基本情報

学部兼担

• 医学部

学位

• 博士（医学）(東京大学)

ID,URL

• J-Global ID

  201401058750905796

researchmap URL

• https://researchmap.jp/7000009356

研究

論文

• Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients.

  Minako Mori; Asuka Hira; Kenichi Yoshida; Hideki Muramatsu; Yusuke Okuno; Yuichi Shiraishi; Michiko Anmae; Jun Yasuda; Shu Tadaka; Kengo Kinoshita; Tomoo Osumi; Yasushi Noguchi; Souichi Adachi; Ryoji Kobayashi; Hiroshi Kawabata; Kohsuke Imai; Tomohiro Morio; Kazuo Tamura; Akifumi Takaori-Kondo; Masayuki Yamamoto; Satoru Miyano; Seiji Kojima; Etsuro Ito; Seishi Ogawa; Keitaro Matsuo; Hiromasa Yabe; Miharu Yabe; Minoru Takata

  Haematologica, 2019年10月, 査読有り

  
• Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia.

  Mahmoud I Elbadry; Hiroki Mizumaki; Kohei Hosokawa; J Luis Espinoza; Noriharu Nakagawa; Kazuhisa Chonabayashi; Yoshinori Yoshida; Takamasa Katagiri; Kazuyoshi Hosomichi; Yoshitaka Zaimoku; Tatsuya Imi; Mai Anh Thi Nguyen; Youichi Fujii; Atsushi Tajima; Seishi Ogawa; Katsuto Takenaka; Koichi Akashi; Shinji Nakao

  Haematologica, 2019年10月, 査読有り

  
• Genetic analysis of a case of Helicobacter pylori-uninfected intramucosal gastric cancer in a family with hereditary diffuse gastric cancer.

  Taro Funakoshi; Shin'ichi Miyamoto; Nobuyuki Kakiuchi; Mitsuhiro Nikaido; Takeshi Setoyama; Akira Yokoyama; Takahiro Horimatsu; Atsushi Yamada; Masako Torishima; Shinji Kosugi; Hidetaka Yamada; Haruhiko Sugimura; Hironori Haga; Yoshiharu Sakai; Seishi Ogawa; Hiroshi Seno; Manabu Muto; Tsutomu Chiba

  Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2019年07月, 査読有り

  
• Genetic and transcriptional landscape of plasma cells in POEMS syndrome.

  Yuhei Nagao; Naoya Mimura; June Takeda; Kenichi Yoshida; Yusuke Shiozawa; Motohiko Oshima; Kazumasa Aoyama; Atsunori Saraya; Shuhei Koide; Ola Rizq; Yoshinori Hasegawa; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Dai Nishijima; Yusuke Isshiki; Kensuke Kayamori; Chika Kawajiri-Manako; Nagisa Oshima-Hasegawa; Shokichi Tsukamoto; Shio Mitsukawa; Yusuke Takeda; Chikako Ohwada; Masahiro Takeuchi; Tohru Iseki; Sonoko Misawa; Satoru Miyano; Osamu Ohara; Koutaro Yokote; Emiko Sakaida; Satoshi Kuwabara; Masashi Sanada; Atsushi Iwama; Seishi Ogawa; Chiaki Nakaseko

  Leukemia, 2019年07月, 査読有り

  
• Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis.

  Soo Ki Kim; Haruhiko Takeda; Atsushi Takai; Tomonori Matsumoto; Nobuyuki Kakiuchi; Akira Yokoyama; Kenichi Yoshida; Toshimi Kaido; Shinji Uemoto; Sachiko Minamiguchi; Hironori Haga; Yuichi Shiraishi; Satoru Miyano; Hiroshi Seno; Seishi Ogawa; Hiroyuki Marusawa

  Journal of gastroenterology, 2019年07月, 査読有り

  
• KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells.

  Hiroshi Kohara; Taiju Utsugisawa; Chika Sakamoto; Lisa Hirose; Yoshie Ogawa; Hiromi Ogura; Ai Sugawara; Jiyuan Liao; Takako Aoki; Takuya Iwasaki; Takayoshi Asai; Sayoko Doisaki; Yusuke Okuno; Hideki Muramatsu; Takaaki Abe; Ryo Kurita; Shohei Miyamoto; Tetsushi Sakuma; Masayuki Shiba; Takashi Yamamoto; Shouichi Ohga; Kenichi Yoshida; Seishi Ogawa; Etsuro Ito; Seiji Kojima; Hitoshi Kanno; Kenzaburo Tani

  Experimental hematology, 2019年05月, 査読有り

  
• Decreased RORC expression and downstream signaling in HTLV-1-associated adult T-cell lymphoma/leukemia uncovers an antiproliferative IL17 link: A potential target for immunotherapy?

  Subramanian K; Dierckx T; Khouri R; Menezes SM; Kagdi H; Taylor GP; Farre L; Bittencourt A; Kataoka K; Ogawa S; Van Weyenbergh J

  International journal of cancer, 2019年04月, 査読有り

  
• Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients.

  Friederike Christen; Kaja Hoyer; Kenichi Yoshida; Hsin-An Hou; Nils Waldhueter; Michael Heuser; Robert K Hills; Willy Chan; Raphael Hablesreiter; Olga Blau; Yotaro Ochi; Piroska Klement; Wen-Chien Chou; Igor-Wolfgang Blau; Jih-Luh Tang; Tomasz Zemojtel; Yuichi Shiraishi; Yusuke Shiozawa; Felicitas Thol; Arnold Ganser; Bob Löwenberg; David C Linch; Lars Bullinger; Peter J M Valk; Hwei-Fang Tien; Rosemary E Gale; Seishi Ogawa; Frederik Damm

  Blood, 2019年03月07日, 査読有り

  
• Molecular pathogenesis of disease progression in MLL-rearranged AML.

  Shinichi Kotani; Akinori Yoda; Ayana Kon; Keisuke Kataoka; Yotaro Ochi; Yusuke Shiozawa; Cassandra Hirsch; June Takeda; Hiroo Ueno; Tetsuichi Yoshizato; Kenichi Yoshida; Masahiro M Nakagawa; Yasuhito Nannya; Nobuyuki Kakiuchi; Takuji Yamauchi; Kosuke Aoki; Yuichi Shiraishi; Satoru Miyano; Takahiro Maeda; Jaroslaw P Maciejewski; Akifumi Takaori-Kondo; Seishi Ogawa; Hideki Makishima

  Leukemia, 2019年03月, 査読有り

  
• Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis.

  Luan Cao-Sy; Naoshi Obara; Tatsuhiro Sakamoto; Takayasu Kato; Keiichiro Hattori; Shingo Sakashita; Yasuhito Nannya; Seishi Ogawa; Hironori Harada; Mamiko Sakata-Yanagimoto; Hidekazu Nishikii; Shigeru Chiba

  International journal of hematology, 2019年03月, 査読有り

  
• Defective Epstein-Barr virus in chronic active infection and haematological malignancy.

  Yusuke Okuno; Takayuki Murata; Yoshitaka Sato; Hideki Muramatsu; Yoshinori Ito; Takahiro Watanabe; Tatsuya Okuno; Norihiro Murakami; Kenichi Yoshida; Akihisa Sawada; Masami Inoue; Keisei Kawa; Masao Seto; Koichi Ohshima; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Yohei Narita; Masahiro Yoshida; Fumi Goshima; Jun-Ichi Kawada; Tetsuya Nishida; Hitoshi Kiyoi; Seiichi Kato; Shigeo Nakamura; Satoko Morishima; Tetsushi Yoshikawa; Shigeyoshi Fujiwara; Norio Shimizu; Yasushi Isobe; Masaaki Noguchi; Atsushi Kikuta; Keiji Iwatsuki; Yoshiyuki Takahashi; Seiji Kojima; Seishi Ogawa; Hiroshi Kimura

  Nature microbiology, 2019年03月, 査読有り

  
• Genetics of MDS.

  Ogawa S

  Blood, 2019年03月, 査読有り

  
• Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia.

  Becker H; Greve G; Kataoka K; Mallm JP; Duque-Afonso J; Ma T; Niemöller C; Pantic M; Duyster J; Cleary ML; Schüler J; Rippe K; Ogawa S; übbert M

  Blood advances, 2019年03月, 査読有り

  
• Publisher Correction: Defective Epstein-Barr virus in chronic active infection and haematological malignancy.

  Yusuke Okuno; Takayuki Murata; Yoshitaka Sato; Hideki Muramatsu; Yoshinori Ito; Takahiro Watanabe; Tatsuya Okuno; Norihiro Murakami; Kenichi Yoshida; Akihisa Sawada; Masami Inoue; Keisei Kawa; Masao Seto; Koichi Ohshima; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Yohei Narita; Masahiro Yoshida; Fumi Goshima; Jun-Ichi Kawada; Tetsuya Nishida; Hitoshi Kiyoi; Seiichi Kato; Shigeo Nakamura; Satoko Morishima; Tetsushi Yoshikawa; Shigeyoshi Fujiwara; Norio Shimizu; Yasushi Isobe; Masaaki Noguchi; Atsushi Kikuta; Keiji Iwatsuki; Yoshiyuki Takahashi; Seiji Kojima; Seishi Ogawa; Hiroshi Kimura

  Nature microbiology, 2019年03月, 査読有り

  
• PAK kinase inhibition has therapeutic activity in novel preclinical models of Adult T-cell Leukemia/Lymphoma.

  Chung EYL; Mai Y; Shah UA; Wei Y; Ishida E; Kataoka K; Ren X; Pradhan K; Bartholdy B; Wei X; Zou Y; Zhang J; Ogawa S; Steidl U; Zang X; Verma A; Janakiram M; Ye BH

  Clinical cancer research : an official journal of the American Association for Cancer Research, 2019年03月, 査読有り

  
• Duplication of ALK F1245 missense mutation due to acquired uniparental disomy associated with aggressive progression in a patient with relapsed neuroblastoma.

  Shunsuke Kimura; Daisuke Hasegawa; Yuri Yoshimoto; Masafumi Seki; Atsuro Daida; Masahiro Sekiguchi; Shinsuke Hirabayashi; Yosuke Hosoya; Masao Kobayashi; Satoru Miyano; Seishi Ogawa; Junko Takita; Atsushi Manabe

  Oncology letters, 2019年03月, 査読有り

  
• Frequent germline mutations of HAVCR2 in sporadic subcutaneous panniculitis-like T-cell lymphoma.

  Chantana Polprasert; Yasuhide Takeuchi; Nobuyuki Kakiuchi; Kenichi Yoshida; Thamathorn Assanasen; Wimonmas Sitthi; Udomsak Bunworasate; Arunrat Pirunsarn; Kitsada Wudhikarn; Panisinee Lawasut; Noppacharn Uaprasert; Sunisa Kongkiatkamon; Chatphatai Moonla; Masashi Sanada; Nobuhiro Akita; June Takeda; Yoichi Fujii; Hiromichi Suzuki; Yasuhito Nannya; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Ponlapat Rojnuckarin; Seishi Ogawa; Hideki Makishima

  Blood advances, 2019年02月26日, 査読有り

  
• Associations of complementation group, ALDH2 genotype, and clonal abnormalities with hematological outcome in Japanese patients with Fanconi anemia.

  Miharu Yabe; Takashi Koike; Keisuke Ohtsubo; Eri Imai; Tsuyoshi Morimoto; Hiromitsu Takakura; Katsuyoshi Koh; Kenichi Yoshida; Seishi Ogawa; Etsuro Ito; Yusuke Okuno; Hideki Muramatsu; Seiji Kojima; Keitaro Matsuo; Minako Mori; Asuka Hira; Minoru Takata; Hiromasa Yabe

  Annals of hematology, 2019年02月, 査読有り

  
• NOTCH1 pathway activating mutations and clonal evolution in pediatric T-cell acute lymphoblastic leukemia.

  Kimura S; Seki M; Yoshida K; Shiraishi Y; Akiyama M; Koh K; Imamura T; Manabe A; Hayashi Y; Kobayashi M; Oka A; Miyano S; Ogawa S; Takita J

  Cancer science, 2019年02月, 査読有り

  
• Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation.

  Frick M; Chan W; Arends CM; Hablesreiter R; Halik A; Heuser M; Michonneau D; Blau O; Hoyer K; Christen F; Galan-Sousa J; Noerenberg D; Wais V; Stadler M; Yoshida K; Schetelig J; Schuler E; Thol F; Clappier E; Christopeit M; Ayuk F; Bornhäuser M; Blau IW; Ogawa S; Zemojtel T; Gerbitz A; Wagner EM; Spriewald BM; Schrezenmeier H; Kuchenbauer F; Kobbe G; Wiesneth M; Koldehoff M; Socié G; Kroeger N; Bullinger L; Thiede C; Damm F

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019年02月, 査読有り

  
• Hematopoietic stem cell transplantation for progressive combined immunodeficiency and lymphoproliferation in patients with activated phosphatidylinositol-3-OH kinase δ syndrome type 1.

  Okano T; Imai K; Tsujita Y; Mitsuiki N; Yoshida K; Kamae C; Honma K; Mitsui-Sekinaka K; Sekinaka Y; Kato T; Hanabusa K; Endo E; Takashima T; Hiroki H; Yeh TW; Tanaka K; Nagahori M; Tsuge I; Bando Y; Iwasaki F; Shikama Y; Inoue M; Kimoto T; Moriguchi N; Yuza Y; Kaneko T; Suzuki K; Matsubara T; Maruo Y; Kunitsu T; Waragai T; Sano H; Hashimoto Y; Tasaki K; Suzuki O; Shirakawa T; Kato M; Uchiyama T; Ishimura M; Tauchi T; Yagasaki H; Jou ST; Yu HH; Kanegane H; Kracker S; Durandy A; Kojima D; Muramatsu H; Wada T; Inoue Y; Takada H; Kojima S; Ogawa S; Ohara O; Nonoyama S; Morio T

  The Journal of allergy and clinical immunology, 2019年01月, 査読有り

  
• Paraneoplastic hypereosinophilic syndrome associated with IL3-IgH positive acute lymphoblastic leukemia.

  Kobayashi K; Mizuta S; Yamane N; Ueno H; Yoshida K; Kato I; Umeda K; Hiramatsu H; Suehiro M; Maihara T; Usami I; Shiraishi Y; Chiba K; Miyano S; Adachi S; Ogawa S; Kiyokawa N; Heike T

  Pediatric blood & cancer, 2019年01月, 査読有り

  
• Clinical significance of ASXL2 and ZBTB7A mutations and C-terminally truncated RUNX1-RUNX1T1 expression in AML patients with t(8;21) enrolled in the JALSG AML201 study.

  Kawashima N; Akashi A; Nagata Y; Kihara R; Ishikawa Y; Asou N; Ohtake S; Miyawaki S; Sakura T; Ozawa Y; Usui N; Kanamori H; Ito Y; Imai K; Suehiro Y; Kitamura K; Sakaida E; Takeshita A; Suzushima H; Naoe T; Matsumura I; Miyazaki Y; Ogawa S; Kiyoi H; Japan Adult Leukemia Study Group (JALSG

  Annals of hematology, 2019年01月, 査読有り

  
• Modification of cellular and humoral immunity by somatically reverted T cells in X-linked lymphoproliferative syndrome type 1.

  Hoshino A; Yang X; Tanita K; Yoshida K; Ono T; Nishida N; Okuno Y; Kanzaki T; Goi K; Fujino H; Ohshima K; Shiraishi Y; Chiba K; Tanaka H; Miyano S; Ogawa S; Kojima S; Morio T; Kanegane H

  The Journal of allergy and clinical immunology, 2019年01月, 査読有り

  
• Age-related remodelling of oesophageal epithelia by mutated cancer drivers.

  Akira Yokoyama; Nobuyuki Kakiuchi; Tetsuichi Yoshizato; Yasuhito Nannya; Hiromichi Suzuki; Yasuhide Takeuchi; Yusuke Shiozawa; Yusuke Sato; Kosuke Aoki; Soo Ki Kim; Yoichi Fujii; Kenichi Yoshida; Keisuke Kataoka; Masahiro M Nakagawa; Yoshikage Inoue; Tomonori Hirano; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Masashi Sanada; Yoshitaka Nishikawa; Yusuke Amanuma; Shinya Ohashi; Ikuo Aoyama; Takahiro Horimatsu; Shin'ichi Miyamoto; Shigeru Tsunoda; Yoshiharu Sakai; Maiko Narahara; J B Brown; Yoshitaka Sato; Genta Sawada; Koshi Mimori; Sachiko Minamiguchi; Hironori Haga; Hiroshi Seno; Satoru Miyano; Hideki Makishima; Manabu Muto; Seishi Ogawa

  Nature, 2019年01月, 査読有り

  
• Novel neuroblastoma amplified sequence (NBAS) mutations in a Japanese boy with fever-triggered recurrent acute liver failure.

  Sahoko Ono; Junko Matsuda; Etsuko Watanabe; Hiroto Akaike; Hideto Teranishi; Ippei Miyata; Takanobu Otomo; Yoshito Sadahira; Tatsuki Mizuochi; Hironori Kusano; Masayoshi Kage; Hiroo Ueno; Kenichi Yoshida; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Seishi Ogawa; Yasuhide Hayashi; Hirokazu Kanegane; Kazunobu Ouchi

  Human genome variation, 2019年, 査読有り

  
• TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.

  Haase D; Stevenson KE; Neuberg D; Maciejewski JP; Nazha A; Sekeres MA; Ebert BL; Garcia-Manero G; Haferlach C; Haferlach T; Kern W; Ogawa S; Nagata Y; Yoshida K; Graubert TA; Walter MJ; List AF; Komrokji RS; Padron E; Sallman D; Papaemmanuil E; Campbell PJ; Savona MR; Seegmiller A; Adès L; Fenaux P; Shih LY; Bowen D; Groves MJ; Tauro S; Fontenay M; Kosmider O; Bar-Natan M; Steensma D; Stone R; Heuser M; Thol F; Cazzola M; Malcovati L; Karsan A; Ganster C, Hellström-Lindberg E; Boultwood J; Pellagatti A; Santini V; Quek L; Vyas P; Tüchler H; Greenberg PL; Bejar R; International Working; Group for; MDS Molecular; Prognostic Committee

  Leukemia, 2019年01月, 査読有り

  
• Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas.

  Kataoka K; Miyoshi H; Sakata S; Dobashi A; Couronné L; Kogure Y; Sato Y; Nishida K; Gion Y; Shiraishi Y; Tanaka H; Chiba K; Watatani Y; Kakiuchi N; Shiozawa Y; Yoshizato T; Yoshida K; Makishima H; Sanada M; Onozawa M; Teshima T; Yoshiki Y; Ishida T; Suzuki K; Shimada K; Tomita A; Kato M; Ota Y; Izutsu K; Demachi-Okamura A; Akatsuka Y; Miyano S; Yoshino T; Gaulard P; Hermine O; Takeuchi K; Ohshima K; Ogawa S

  Leukemia, 2019年01月, 査読有り

  
• [Successful treatment of pure red cell aplasia with cyclosporin in a patient with T-cell large granular lymphocytic leukemia harboring the STAT3 D661V mutation].

  Adachi M; Yoshida K; Shiraishi Y; Chiba K; Miyano S; Ogawa S

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2019年, 査読有り

  
• Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.

  Shelar S; Shim EH; Brinkley GJ; Kundu A; Carobbio F; Poston T; Tan J; Parekh V; Benson D; Crossman DK; Buckhaults PJ; Rakheja D; Kirkman R; Sato Y; Ogawa S; Dutta S; Velu SE; Emberley E; Pan A; Chen J; Huang T; Absher D; Becker A; Kunick C; Sudarshan S

  Clinical cancer research : an official journal of the American Association for Cancer Research, 2018年12月, 査読有り

  
• Two siblings with familial neuroblastoma with distinct clinical phenotypes harboring an ALK germline mutation.

  Ko Kudo; Hiroo Ueno; Tomohiko Sato; Kaori Kubo; Rika Kanezaki; Akie Kobayashi; Takuya Kamio; Shinya Sasaki; Kiminori Terui; Akira Kurose; Kenichi Yoshida; Yusuke Shiozawa; Tsutomu Toki; Seishi Ogawa; Etsuro Ito

  Genes, chromosomes & cancer, 2018年12月, 査読有り

  
• Recurrent CCND3 mutations in MLL-rearranged acute myeloid leukemia.

  Hidemasa Matsuo; Kenichi Yoshida; Kazutaka Fukumura; Kana Nakatani; Yuki Noguchi; Saho Takasaki; Mina Noura; Yusuke Shiozawa; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Ai Okada; Yasuhito Nannya; June Takeda; Hiroo Ueno; Norio Shiba; Genki Yamato; Hiroshi Handa; Yuichiro Ono; Nobuhiro Hiramoto; Takayuki Ishikawa; Kensuke Usuki; Ken Ishiyama; Shuichi Miyawaki; Hidehiro Itonaga; Yasushi Miyazaki; Machiko Kawamura; Hiroki Yamaguchi; Nobutaka Kiyokawa; Daisuke Tomizawa; Takashi Taga; Akio Tawa; Yasuhide Hayashi; Hiroyuki Mano; Satoru Miyano; Yasuhiko Kamikubo; Seishi Ogawa; Souichi Adachi

  Blood advances, 2018年11月13日, 査読有り

  この論文にアクセスする：

  
• Gain-of-function IKBKB mutation causes human combined immune deficiency.

  Chelisa Cardinez; Bahar Miraghazadeh; Kay Tanita; Elizabeth da Silva; Akihiro Hoshino; Satoshi Okada; Rochna Chand; Takaki Asano; Miyuki Tsumura; Kenichi Yoshida; Hidenori Ohnishi; Zenichiro Kato; Masahide Yamazaki; Yusuke Okuno; Satoru Miyano; Seiji Kojima; Seishi Ogawa; T Daniel Andrews; Matthew A Field; Gaetan Burgio; Tomohiro Morio; Carola G Vinuesa; Hirokazu Kanegane; Matthew C Cook

  The Journal of experimental medicine, 2018年11月05日, 査読有り

  
• Sudden Intracranial Hemorrhage in a Patient With Atypical Chronic Myeloid Leukemia in Chronic Phase.

  Kagehiro Kouzuki; Katsutsugu Umeda; Satoshi Saida; Itaru Kato; Hidefumi Hiramatsu; Takeshi Funaki; Kenji Kanda; Hideki Muramatsu; Kenichi Yoshida; Seishi Ogawa; Souichi Adachi

  Journal of pediatric hematology/oncology, 2018年11月, 査読有り

  
• Clonally related diffuse large B-cell lymphoma and interdigitating dendritic cell sarcoma sharing MYC translocation.

  Yotaro Ochi; Nobuhiro Hiramoto; Tetsuichi Yoshizato; Yuichiro Ono; June Takeda; Yusuke Shiozawa; Kenichi Yoshida; Nobuyuki Kakiuchi; Yuichi Shiraishi; Hiroko Tanaka; Kenichi Chiba; Yasuhiro Kazuma; Sumie Tabata; Noboru Yonetani; Keiichiro Uehara; Daisuke Yamashita; Yukihiro Imai; Koji Nagafuji; Mitsunori Yamakawa; Satoru Miyano; Akifumi Takaori-Kondo; Seishi Ogawa; Takayuki Ishikawa

  Haematologica, 2018年11月, 査読有り

  
• Germline loss-of-function SAMD9 and SAMD9L alterations in adult myelodysplastic syndromes.

  Nagata Y; Narumi S; Guan Y; Przychodzen BP; Hirsch CM; Makishima H; Shima H; Aly M; Pastor V; Kuzmanovic T; Radivoyevitch T; Adema V; Awada H; Yoshida K; Li S; Sole F; Hanna R; Jha BK; LaFramboise T; Ogawa S; Sekeres MA; Wlodarski MW; Cammenga J; Maciejewski JP

  Blood, 2018年11月, 査読有り

  
• Blastic plasmacytoid dendritic cell neoplasm arising from clonal hematopoiesis.

  Suma S; Sakata-Yanagimoto M; Nguyen TB; Hattori K; Sato T; Noguchi M; Nannya Y; Ogawa S; Watanabe R; Fujimoto M; Nakamura N; Kusakabe M; Nishikii H; Kato T; Chiba S

  International journal of hematology, 2018年10月, 査読有り

  
• North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies.

  Shah UA; Chung EY; Giricz O; Pradhan K; Kataoka K; Gordon-Mitchell S; Bhagat TD; Mai Y; Wei Y; Ishida E; Choudhary GS; Joseph A; Rice R; Gitego N; Parrish C; Bartenstein M; Goel S; Mantzaris I; Shastri A; Derman O; Binder A; Gritsman K; Kornblum N; Braunschweig I; Bhagat C; Hall J; Graber A; Ratner L; Wang Y; Ogawa S; Verma A; Ye BH; Janakiram M

  Blood, 2018年10月, 査読有り

  
• Infection perturbs Bach2- and Bach1-dependent erythroid lineage 'choice' to cause anemia.

  Hiroki Kato; Ari Itoh-Nakadai; Mitsuyo Matsumoto; Yusho Ishii; Miki Watanabe-Matsui; Masatoshi Ikeda; Risa Ebina-Shibuya; Yuki Sato; Masahiro Kobayashi; Hironari Nishizawa; Katsushi Suzuki; Akihiko Muto; Tohru Fujiwara; Yasuhito Nannya; Luca Malcovati; Mario Cazzola; Seishi Ogawa; Hideo Harigae; Kazuhiko Igarashi

  Nature immunology, 2018年10月, 査読有り

  
• Identification of a Novel Titin Variant Underlying Myocardial Involvement in Neurofibromatosis Type 1.

  Mami Kizawa; Yu Nakagama; Takahiro Shindo; Seishi Ogawa; Ryo Inuzuka

  The Canadian journal of cardiology, 2018年10月, 査読有り

  
• De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome.

  Tsutomu Toki; Kenichi Yoshida; RuNan Wang; Sou Nakamura; Takanobu Maekawa; Kumiko Goi; Megumi C Katoh; Seiya Mizuno; Fumihiro Sugiyama; Rika Kanezaki; Tamayo Uechi; Yukari Nakajima; Yusuke Sato; Yusuke Okuno; Aiko Sato-Otsubo; Yusuke Shiozawa; Keisuke Kataoka; Yuichi Shiraishi; Masashi Sanada; Kenichi Chiba; Hiroko Tanaka; Kiminori Terui; Tomohiko Sato; Takuya Kamio; Hirotoshi Sakaguchi; Shouichi Ohga; Madoka Kuramitsu; Isao Hamaguchi; Akira Ohara; Hitoshi Kanno; Satoru Miyano; Seiji Kojima; Akira Ishiguro; Kanji Sugita; Naoya Kenmochi; Satoru Takahashi; Koji Eto; Seishi Ogawa; Etsuro Ito

  American journal of human genetics, 2018年09月06日, 査読有り

  
• Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.

  Arends CM; Galan-Sousa J; Hoyer K; Chan W; Jäger M; Yoshida K; Seemann R; Noerenberg D; Waldhueter N; Fleischer-Notter H; Christen F; Schmitt CA; Dörken B; Pelzer U; Sinn M; Zemojtel T; Ogawa S; Märdian S; Schreiber A; Kunitz A; Krüger U; Bullinger L; Mylonas E; Frick M; Damm F

  Leukemia, 2018年09月, 査読有り

  
• Whole-exome analysis to detect congenital hemolytic anemia mimicking congenital dyserythropoietic anemia.

  Motoharu Hamada; Sayoko Doisaki; Yusuke Okuno; Hideki Muramatsu; Asahito Hama; Nozomu Kawashima; Atsushi Narita; Nobuhiro Nishio; Kenichi Yoshida; Hitoshi Kanno; Atsushi Manabe; Takashi Taga; Yoshiyuki Takahashi; Satoru Miyano; Seishi Ogawa; Seiji Kojima

  International journal of hematology, 2018年09月, 査読有り

  
• Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia.

  Shiozawa Y; Malcovati L; Gallì A; Sato-Otsubo A; Kataoka K; Sato Y; Watatani Y; Suzuki H; Yoshizato T; Yoshida K; Sanada M; Makishima H; Shiraishi Y; Chiba K; Hellström-Lindberg E; Miyano S; Ogawa S; Cazzola M

  Nature communications, 2018年09月, 査読有り

  この論文にアクセスする：

  
• Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation.

  Tomoo Osumi; Shin-Ichi Tsujimoto; Moe Tamura; Meri Uchiyama; Kazuhiko Nakabayashi; Kohji Okamura; Masanori Yoshida; Daisuke Tomizawa; Akihiro Watanabe; Hiroyuki Takahashi; Tsukasa Hori; Shohei Yamamoto; Kazuko Hamamoto; Masahiro Migita; Hiroko Ogata-Kawata; Toru Uchiyama; Hiroe Kizawa; Hitomi Ueno-Yokohata; Ryota Shirai; Masafumi Seki; Kentaro Ohki; Junko Takita; Takeshi Inukai; Seishi Ogawa; Toshio Kitamura; Kimikazu Matsumoto; Kenichiro Hata; Nobutaka Kiyokawa; Susumu Goyama; Motohiro Kato

  Cancer research, 2018年08月15日, 査読有り

  
• A Cryptic NUP214-ABL1 Fusion in B-cell Precursor Acute Lymphoblastic Leukemia.

  Shin-Ichi Tsujimoto; Yoshiko Nakano; Tomoo Osumi; Keiko Okada; Meri Ouchi-Uchiyama; Keisuke Kataoka; Yoichi Fujii; Kentaro Ohki; Masafumi Seki; Nobuyoshi Tamagawa; Junko Takita; Seishi Ogawa; Nobutaka Kiyokawa; Junichi Hara; Motohiro Kato

  Journal of pediatric hematology/oncology, 2018年08月, 査読有り

  
• RNA fusions involving CD28 are rare in peripheral T-cell lymphomas and concentrate mainly in those derived from follicular helper T cells.

  Vallois D; Dupuy A; Lemonnier F; Allen G; Missiaglia E; Fataccioli V; Ortonne N; Clavert A; Delarue R; Rousselet MC; Fabiani B; Llamas-Gutierrez F; Ogawa S; Thome M; Ko YH; Kataoka K; Gaulard P; de Leval L

  Haematologica, 2018年08月, 査読有り

  
• The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.

  Motoyuki Tsuda; Akihisa Fukuda; Nilotpal Roy; Yukiko Hiramatsu; Laura Leonhardt; Nobuyuki Kakiuchi; Kaja Hoyer; Satoshi Ogawa; Norihiro Goto; Kozo Ikuta; Yoshito Kimura; Yoshihide Matsumoto; Yutaka Takada; Takuto Yoshioka; Takahisa Maruno; Yuichi Yamaga; Grace E Kim; Haruhiko Akiyama; Seishi Ogawa; Christopher V Wright; Dieter Saur; Kyoichi Takaori; Shinji Uemoto; Matthias Hebrok; Tsutomu Chiba; Hiroshi Seno

  The Journal of clinical investigation, 2018年08月01日, 査読有り

  
• A comprehensive characterization of cis-acting splicing-associated variants in human cancer.

  Shiraishi Y; Kataoka K; Chiba K; Okada A; Kogure Y; Tanaka H; Ogawa S; Miyano S

  Genome research, 2018年08月, 査読有り

  
• ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion.

  Madan V; Han L; Hattori N; Teoh WW; Mayakonda A; Sun QY; Ding LW; Binte Moh; Nordin H; Lim SL; Shyamsunder P; Dakle P; Sundaresan J; Doan NB; Sanada M; Sato-Otsubo A; Meggendorfer M; Yang H; Said JW; Ogawa S; Haferlach T; Liang DC; Shih LY; Nakamaki T; Wang QT; Koeffler HP

  Haematologica, 2018年08月, 査読有り

  
• PD-1 Inhibitor Therapy in Adult T-Cell Leukemia–Lymphoma.

  Kataoka K; Ogawa S

  The New England journal of medicine, 2018年08月, 査読有り

  
• A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer.

  Tomoko Saito; Atsushi Niida; Ryutaro Uchi; Hidenari Hirata; Hisateru Komatsu; Shotaro Sakimura; Shuto Hayashi; Sho Nambara; Yosuke Kuroda; Shuhei Ito; Hidetoshi Eguchi; Takaaki Masuda; Keishi Sugimachi; Taro Tobo; Haruto Nishida; Tsutomu Daa; Kenichi Chiba; Yuichi Shiraishi; Tetsuichi Yoshizato; Masaaki Kodama; Tadayoshi Okimoto; Kazuhiro Mizukami; Ryo Ogawa; Kazuhisa Okamoto; Mitsutaka Shuto; Kensuke Fukuda; Yusuke Matsui; Teppei Shimamura; Takanori Hasegawa; Yuichiro Doki; Satoshi Nagayama; Kazutaka Yamada; Mamoru Kato; Tatsuhiro Shibata; Masaki Mori; Hiroyuki Aburatani; Kazunari Murakami; Yutaka Suzuki; Seishi Ogawa; Satoru Miyano; Koshi Mimori

  Nature communications, 2018年07月23日, 査読有り

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• Dysregulation of Epstein-Barr Virus Infection in Hypomorphic ZAP70 Mutation.

  Hoshino A; Takashima T; Yoshida K; Morimoto A; Kawahara Y; Yeh TW; Okano T; Yamashita M; Mitsuiki N; Imai K; Sakatani T; Nakazawa A; Okuno Y; Shiraishi Y; Chiba K; Tanaka H; Miyano S; Ogawa S; Kojima S; Morio T; Kanegane H

  The Journal of infectious diseases, 2018年07月, 査読有り

  
• Glucagonoma With Necrolytic Migratory Erythema: Metabolic Profile and Detection of Biallelic Inactivation of DAXX Gene.

  Ai Tamura; Tatsuki Ogasawara; Yoichi Fujii; Hiyori Kaneko; Akitoshi Nakayama; Seiichiro Higuchi; Naoko Hashimoto; Yui Miyabayashi; Masanori Fujimoto; Eri Komai; Takashi Kono; Ikki Sakuma; Hidekazu Nagano; Sawako Suzuki; Hisashi Koide; Koutaro Yokote; Kozue Iseki; Rena Oguma; Hiroyuki Matsue; Hiroyuki Nojima; Kensuke Sugiura; Hideyuki Yoshitomi; Masayuki Ohtsuka; Bahityar Rahmutulla; Atsushi Kaneda; Naoko Inoshita; Seishi Ogawa; Tomoaki Tanaka

  The Journal of clinical endocrinology and metabolism, 2018年07月01日, 査読有り

  
• Hidden FLT3-D835Y clone in FLT3-ITD-positive acute myeloid leukemia that evolved into very late relapse with T-lymphoblastic leukemia

  Seiichiro Katagiri; Tomohiro Umezu; Kenko Azuma; Michiyo Asano; Daigo Akahane; Hideki Makishima; Kenichi Yoshida; Yosaku Watatani; Kenichi Chiba; Satoru Miyano; Seishi Ogawa; Junko H. Ohyashiki; Kazuma Ohyashiki

  Leukemia and Lymphoma, 2018年06月03日, 査読有り

  
• RUNX1 mutations in pediatric acute myeloid leukemia are associated with distinct genetic features and an inferior prognosis.

  Genki Yamato; Norio Shiba; Kenichi Yoshida; Yusuke Hara; Yuichi Shiraishi; Kentaro Ohki; Jun Okubo; Myoung-Ja Park; Manabu Sotomatsu; Hirokazu Arakawa; Nobutaka Kiyokawa; Daisuke Tomizawa; Souichi Adachi; Takashi Taga; Keizo Horibe; Satoru Miyano; Seishi Ogawa; Yasuhide Hayashi

  Blood, 2018年05月17日, 査読有り

  
• Sustained clonal hematopoiesis by HLA-lacking hematopoietic stem cells without driver mutations in aplastic anemia.

  Tatsuya Imi; Takamasa Katagiri; Kazuyoshi Hosomichi; Yoshitaka Zaimoku; Viet Hoang Nguyen; Noriharu Nakagawa; Atsushi Tajima; Tetsuichi Yoshizato; Seishi Ogawa; Shinji Nakao

  Blood advances, 2018年05月08日, 査読有り

  
• Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT

  Gerbrig Berger; Leonie I. Kroeze; Theresia N. Koorenhof-Scheele; Aniek O. De Graaf; Kenichi Yoshida; Hiroo Ueno; Yuichi Shiraishi; Satoru Miyano; Eva Van Den Berg; Hein Schepers; Bert A. Van Der Reijden; Seishi Ogawa; Edo Vellenga; Joop H. Jansen

  Blood, 2018年04月19日, 査読有り

  
• Integrated molecular profiling of juvenile myelomonocytic leukemia.

  Norihiro Murakami; Yusuke Okuno; Kenichi Yoshida; Yuichi Shiraishi; Genta Nagae; Kyogo Suzuki; Atsushi Narita; Hirotoshi Sakaguchi; Nozomu Kawashima; Xinan Wang; Yinyan Xu; Kenichi Chiba; Hiroko Tanaka; Asahito Hama; Masashi Sanada; Masafumi Ito; Masashi Hirayama; Arata Watanabe; Toshihide Ueno; Seiji Kojima; Hiroyuki Aburatani; Hiroyuki Mano; Satoru Miyano; Seishi Ogawa; Yoshiyuki Takahashi; Hideki Muramatsu

  Blood, 2018年04月05日, 査読有り

  
• Progression to polythythemia vera from familial thrombocytosis with germline JAK2 R867Q mutation

  Koichiro Maie; Yasuhisa Yokoyama; Yoko Yano; Takayasu Kato; Yasuhito Nannya; Seishi Ogawa; Masayuki Noguchi; Mamiko Sakata-Yanagimoto; Shigeru Chiba

  Annals of Hematology, 2018年04月01日, 査読有り

  
• Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study

  Yasuhiko Harada; for the Japan Adult Leukemia Study Group JALSG; Yasunobu Nagata; Rika Kihara; Yuichi Ishikawa; Norio Asou; Shigeki Ohtake; Shuichi Miyawaki; Toru Sakura; Yukiyasu Ozawa; Noriko Usui; Heiwa Kanamori; Yoshikazu Ito; Kiyotoshi Imai; Youko Suehiro; Shinichi Kobayashi; Kunio Kitamura; Emiko Sakaida; Makoto Onizuka; Akihiro Takeshita; Fumihiro Ishida; Hitoshi Suzushima; Kenichi Ishizawa; Tomoki Naoe; Itaru Matsumura; Yasushi Miyazaki; Seishi Ogawa; Hitoshi Kiyoi

  Leukemia Research, 2018年03月01日, 査読有り

  
• Integrated Molecular Characterization of the Lethal Pediatric Cancer Pancreatoblastoma.

  Tomoya Isobe; Masafumi Seki; Kenichi Yoshida; Masahiro Sekiguchi; Yusuke Shiozawa; Yuichi Shiraishi; Shunsuke Kimura; Misa Yoshida; Yoshikage Inoue; Akira Yokoyama; Nobuyuki Kakiuchi; Hiromichi Suzuki; Keisuke Kataoka; Yusuke Sato; Tomoko Kawai; Kenichi Chiba; Hiroko Tanaka; Teppei Shimamura; Motohiro Kato; Akihiro Iguchi; Asahito Hama; Tomoaki Taguchi; Masaharu Akiyama; Junya Fujimura; Akiko Inoue; Tsuyoshi Ito; Takao Deguchi; Chikako Kiyotani; Tomoko Iehara; Hajime Hosoi; Akira Oka; Masashi Sanada; Yukichi Tanaka; Kenichiro Hata; Satoru Miyano; Seishi Ogawa; Junko Takita

  Cancer research, 2018年02月15日, 査読有り

  
• Evolutionary basis of HLA-DPB1 alleles affects acute GVHD in unrelated donor stem cell transplantation

  Satoko Morishima; Takashi Shiina; Shingo Suzuki; Seishi Ogawa; Aiko Sato-Otsubo; Koichi Kashiwase; Fumihiro Azuma; Toshio Yabe; Masahiro Satake; Shunichi Kato; Yoshihisa Kodera; Takehiko Sasazuki; Yasuo Morishima

  Blood, 2018年02月15日, 査読有り

  
• Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice

  Ayana Kon; Satoshi Yamazaki; Yasuhito Nannya; Keisuke Kataoka; Yasunori Ota; Masahiro Marshall Nakagawa; Kenichi Yoshida; Yusuke Shiozawa; Maiko Morita; Tetsuichi Yoshizato; Masashi Sanada; Manabu Nakayama; Haruhiko Koseki; Hiromitsu Nakauchi; Seishi Ogawa

  Blood, 2018年02月08日, 査読有り

  
• Genetic heterogeneity of uncharacterized childhood autoimmune diseases with lymphoproliferation

  Masatoshi Takagi; Akihiro Hoshino; Kenichi Yoshida; Hiroo Ueno; Kohsuke Imai; Jinhua Piao; Hirokazu Kanegane; Motoi Yamashita; Tsubasa Okano; Hideki Muramatsu; Yusuke Okuno; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Seishi Ogawa; Yasuhide Hayashi; Seiji Kojima; Tomohiro Morio

  Pediatric Blood and Cancer, 2018年02月01日, 査読有り

  
• Prognostic value of genetic mutations in adolescent and young adults with acute myeloid leukemia.

  Yachiyo Kuwatsuka; Daisuke Tomizawa; Rika Kihara; Yasunobu Nagata; Norio Shiba; Yuka Iijima-Yamashita; Akira Shimada; Takao Deguchi; Hayato Miyachi; Akio Tawa; Takashi Taga; Akitoshi Kinoshita; Hideki Nakayama; Nobutaka Kiyokawa; Akiko Moriya Saito; Katsuyoshi Koh; Hiroaki Goto; Yoshiyuki Kosaka; Norio Asou; Shigeki Ohtake; Shuichi Miyawaki; Yasushi Miyazaki; Toru Sakura; Yukiyasu Ozawa; Noriko Usui; Heiwa Kanamori; Yoshikazu Ito; Kiyotoshi Imai; Youko Suehiro; Shinichi Kobayashi; Kunio Kitamura; Emiko Sakaida; Seishi Ogawa; Tomoki Naoe; Yasuhide Hayashi; Keizo Horibe; Atsushi Manabe; Shuki Mizutani; Souichi Adachi; Hitoshi Kiyoi

  International journal of hematology, 2018年02月, 査読有り

  
• Distinct gene alterations with a high percentage of myeloperoxidase-positive leukemic blasts in de novo acute myeloid leukemia.

  Rena Kamijo; Hidehiro Itonaga; Rika Kihara; Yasunobu Nagata; Tomoko Hata; Norio Asou; Shigeki Ohtake; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Seishi Ogawa; Tomoki Naoe; Hitoshi Kiyoi; Yasushi Miyazaki

  Leukemia research, 2018年02月, 査読有り

  
• Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma.

  Keisuke Kataoka; Masako Iwanaga; Jun-Ichirou Yasunaga; Yasunobu Nagata; Akira Kitanaka; Takuro Kameda; Makoto Yoshimitsu; Yuichi Shiraishi; Aiko Sato-Otsubo; Masashi Sanada; Kenichi Chiba; Hiroko Tanaka; Yotaro Ochi; Kosuke Aoki; Hiromichi Suzuki; Yusuke Shiozawa; Tetsuichi Yoshizato; Yusuke Sato; Kenichi Yoshida; Kisato Nosaka; Masakatsu Hishizawa; Hidehiro Itonaga; Yoshitaka Imaizumi; Wataru Munakata; Kotaro Shide; Yoko Kubuki; Tomonori Hidaka; Tsuyoshi Nakamaki; Ken Ishiyama; Shuichi Miyawaki; Ryohei Ishii; Osamu Nureki; Kensei Tobinai; Yasushi Miyazaki; Akifumi Takaori-Kondo; Tatsuhiro Shibata; Satoru Miyano; Kenji Ishitsuka; Atae Utsunomiya; Kazuya Shimoda; Masao Matsuoka; Toshiki Watanabe; Seishi Ogawa

  Blood, 2018年01月11日, 査読有り

  
• Immune-Mediated Hematopoietic Failure after Allogeneic Hematopoietic Stem Cell Transplantation: A Common Cause of Late Graft Failure in Patients with Complete Donor Chimerism.

  Kana Maruyama; Nobuyuki Aotsuka; Yoshihisa Kumano; Naoko Sato; Naomi Kawashima; Yoshiyuki Onda; Hiroyuki Maruyama; Takamasa Katagiri; Yoshitaka Zaimoku; Noriharu Nakagawa; Kazuyoshi Hosomichi; Seishi Ogawa; Shinji Nakao

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018年01月, 査読有り

  
• Prognostic relevance of genetic alterations in diffuse lower-grade gliomas

  Kosuke Aoki; Hideo Nakamura; Hiromichi Suzuki; Keitaro Matsuo; Keisuke Kataoka; Teppei Shimamura; Kazuya Motomura; Fumiharu Ohka; Satoshi Shiina; Takashi Yamamoto; Yasunobu Nagata; Tetsuichi Yoshizato; Masahiro Mizoguchi; Tatsuya Abe; Yasutomo Momii; Yoshihiro Muragaki; Reiko Watanabe; Ichiro Ito; Masashi Sanada; Hironori Yajima; Naoya Morita; Ichiro Takeuchi; Satoru Miyano; Toshihiko Wakabayashi; Seishi Ogawa; Atsushi Natsume

  Neuro-Oncology, 2018年01月01日, 査読有り

  
• 骨髄異形成症候群の臨床像と体細胞遺伝子変異との関連

  平沢 伸広; 小川 誠司; 長谷川 雄一; 千葉 滋; 坂田(柳元) 麻実子; 南谷 泰仁; 服部 圭一郎; 末原 泰人; 加藤 貴康; 横山 泰久; 栗田 尚樹; 小原 直

  臨床血液, 2018年, 査読有り

  
• Identification of the genetic and clinical characteristics of neuroblastomas using genome-wide analysis.

  Kumiko Uryu; Riki Nishimura; Keisuke Kataoka; Yusuke Sato; Atsuko Nakazawa; Hiromichi Suzuki; Kenichi Yoshida; Masafumi Seki; Mitsuteru Hiwatari; Tomoya Isobe; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Katsuyoshi Koh; Ryoji Hanada; Akira Oka; Yasuhide Hayashi; Miki Ohira; Takehiko Kamijo; Hiroki Nagase; Tetsuya Takimoto; Tatsuro Tajiri; Akira Nakagawara; Seishi Ogawa; Junko Takita

  Oncotarget, 2017年12月08日, 査読有り

  
• Constitutional abnormalities of IDH1 combined with secondary mutations predispose a patient with Maffucci syndrome to acute lymphoblastic leukemia

  Shinsuke Hirabayashi; Masafumi Seki; Daisuke Hasegawa; Motohiro Kato; Nobuyuki Hyakuna; Takuya Shuo; Shunsuke Kimura; Kenichi Yoshida; Keisuke Kataoka; Yoichi Fujii; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Nobutaka Kiyokawa; Satoru Miyano; Seishi Ogawa; Junko Takita; Atsushi Manabe

  PEDIATRIC BLOOD & CANCER, 2017年12月, 査読有り

  
• Significance of perivascular tumour cells defined by CD109 expression in progression of glioma

  Yukihiro Shiraki; Shinji Mii; Atsushi Enomoto; Hiroyuki Momota; Yi-Peng Han; Takuya Kato; Kaori Ushida; Akira Kato; Naoya Asai; Yoshiki Murakumo; Kosuke Aoki; Hiromichi Suzuki; Fumiharu Ohka; Toshihiko Wakabayashi; Tomoki Todo; Seishi Ogawa; Atsushi Natsume; Masahide Takahashi

  JOURNAL OF PATHOLOGY, 2017年12月, 査読有り

  
• Gene expression and risk of leukemic transformation in myelodysplasia

  Yusuke Shiozawa; Luca Malcovati; Anna Galli; Andrea Pellagatti; Mohsen Karimi; Aiko Sato-Otsubo; Yusuke Sato; Hiromichi Suzuki; Tetsuichi Yoshizato; Kenichi Yoshida; Yuichi Shiraishi; Kenichi Chiba; Hideki Makishima; Jacqueline Boultwood; Eva Hellstrom-Lindberg; Satoru Miyano; Mario Cazzola; Seishi Ogawa

  BLOOD, 2017年12月, 査読有り

  
• Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor.

  Takagi M; Yoshida M; Nemoto Y; Tamaichi H; Tsuchida R; Seki M; Uryu K; Nishii R; Miyamoto S; Saito M; Hanada R; Kaneko H; Miyano S; Kataoka K; Yoshida K; Ohira M; Hayashi Y; Nakagawara A; Ogawa S; Mizutani S; Takita J

  Journal of the National Cancer Institute, 2017年11月, 査読有り

  
• Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells

  Ken Morita; Mina Noura; Chieko Tokushige; Shintaro Maeda; Hiroki Kiyose; Gengo Kashiwazaki; Junichi Taniguchi; Toshikazu Bando; Kenichi Yoshida; Toshifumi Ozaki; Hidemasa Matsuo; Seishi Ogawa; Pu Paul Liu; Tatsutoshi Nakahata; Hiroshi Sugiyama; Souichi Adachi; Yasuhiko Kamikubo

  SCIENTIFIC REPORTS, 2017年11月, 査読有り

  この論文にアクセスする：

  
• Two patients with 19p13.2 deletion (Malan syndrome) involving NFIX and CACNA1A with overgrowth, developmental delay, and epilepsy

  Yukiko Kuroda; Yoko Mizuno; Masakazu Mimaki; Akira Oka; Yusuke Sato; Seishi Ogawa; Kenji Kurosawa

  CLINICAL DYSMORPHOLOGY, 2017年10月, 査読有り

  
• Integration of Recurrent Somatic Mutations with Clinical Outcomes: A Pooled Analysis of 1049 Patients with Clear Cell Renal Cell Carcinoma

  Brandon John Manley; Emily C. Zabor; Jozefina Casuscelli; Daniel M. Tennenbaum; Almedina Redzematovic; Maria F. Becerra; Nicole Benfante; Yusuke Sato; Teppei Morikawa; Haruki Kume; Masashi Fukayama; Yukio Homma; Seishi Ogawa; Maria E. Arcila; Martin H. Voss; Darren R. Feldman; Jonathan A. Coleman; Victor E. Reuter; Robert J. Motzer; Paul Russo; James J. Hsieh; A. Ari Hakimi

  European Urology Focus, 2017年10月01日, 査読有り

  
• Origins of myelodysplastic syndromes after aplastic anemia

  Eiju Negoro; Yasunobu Nagata; Michael J. Clemente; Naoko Hosono; Wenyi Shen; Aziz Nazha; Tetsuichi Yoshizato; Cassandra Hirsch; Bartlomiej Przychodzen; Reda Z. Mahfouz; Teodora Kuzmanovic; Mikkael A. Sekeres; Hideki Makishima; Seishi Ogawa; Jaroslaw P. Maciejewski

  BLOOD, 2017年10月, 査読有り

  
• Blastic transformation of juvenile myelomonocytic leukemia caused by the copy number gain of oncogenic KRAS

  Tomoo Osumi; Motohiro Kato; Meri Ouchi-Uchiyama; Daisuke Tomizawa; Keisuke Kataoka; Yoichi Fujii; Masafumi Seki; Junko Takita; Seishi Ogawa; Toru Uchiyama; Kentaro Ohki; Nobutaka Kiyokawa

  PEDIATRIC BLOOD & CANCER, 2017年09月, 査読有り

  
• The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.

  Yip BH; Steeples V; Repapi E; Armstrong RN; Llorian M; Roy S; Shaw J; Dolatshad H; Taylor S; Verma A; Bartenstein M; Vyas P; Cross NC; Malcovati L; Cazzola M; Hellström-Lindberg E; Ogawa S; Smith CW; Pellagatti A; Boultwood J

  The Journal of clinical investigation, 2017年09月, 査読有り

  
• Atypical dyskeratosis congenita diagnosed using whole-exome sequencing

  Ayaka Monoi; Masahiro Sugawa; Motohiro Kato; Masafumi Seki; Kenichi Yoshida; Yuichi Shiraishi; Hirotoshi Sakaguchi; Seishi Ogawa; Junko Takita

  PEDIATRICS INTERNATIONAL, 2017年08月, 査読有り

  
• Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia

  Masafumi Seki; Shunsuke Kimura; Tomoya Isobe; Kenichi Yoshida; Hiroo Ueno; Yaeko Nakajima-Takagi; Changshan Wang; Lin Lin; Ayana Kon; Hiromichi Suzuki; Yusuke Shiozawa; Keisuke Kataoka; Yoichi Fujii; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Teppei Shimamura; Kyoko Masuda; Hiroshi Kawamoto; Kentaro Ohki; Motohiro Kato; Yuki Arakawa; Katsuyoshi Koh; Ryoji Hanada; Hiroshi Moritake; Masaharu Akiyama; Ryoji Kobayashi; Takao Deguchi; Yoshiko Hashii; Toshihiko Imamura; Atsushi Sato; Nobutaka Kiyokawa; Akira Oka; Yasuhide Hayashi; Masatoshi Takagi; Atsushi Manabe; Akira Ohara; Keizo Horibe; Masashi Sanada; Atsushi Iwama; Hiroyuki Mano; Satoru Miyano; Seishi Ogawa; Junko Takita

  NATURE GENETICS, 2017年08月, 査読有り

  
• Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype

  Mitsuteru Hiwatari; Masafumi Seki; Shogo Akahoshi; Kenichi Yoshida; Satoru Miyano; Yuichi Shiraishi; Hiroko Tanaka; Kenichi Chiba; Seishi Ogawa; Junko Takita

  ONCOLOGY LETTERS, 2017年08月, 査読有り

  
• Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations

  Akihiro Hoshino; Satoshi Okada; Kenichi Yoshida; Naonori Nishida; Yusuke Okuno; Hiroo Ueno; Motoi Yamashita; Tsubasa Okano; Miyuki Tsumura; Shiho Nishimura; Sonoko Sakata; Masao Kobayashi; Haruna Nakamura; Junji Kamizono; Kanako Mitsui-Sekinaka; Takuya Ichimura; Shouichi Ohga; Yozo Nakazawa; Masatoshi Takagi; Kohsuke Imai; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Seishi Ogawa; Seiji Kojima; Shigeaki Nonoyama; Tomohiro Morio; Hirokazu Kanegane

  JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017年07月, 査読有り

  
• Clinical utility of next-generation sequencing for inherited bone marrow failure syndromes

  Hideki Muramatsu; Yusuke Okuno; Kenichi Yoshida; Yuichi Shiraishi; Sayoko Doisaki; Atsushi Narita; Hirotoshi Sakaguchi; Nozomu Kawashima; Xinan Wang; Yinyan Xu; Kenichi Chiba; Hiroko Tanaka; Asahito Hama; Masashi Sanada; Yoshiyuki Takahashi; Hitoshi Kanno; Hiroki Yamaguchi; Shouichi Ohga; Atsushi Manabe; Hideo Harigae; Shinji Kunishima; Eiichi Ishii; Masao Kobayashi; Kenichi Koike; Kenichiro Watanabe; Etsuro Ito; Minoru Takata; Miharu Yabe; Seishi Ogawa; Satoru Miyano; Seiji Kojima

  GENETICS IN MEDICINE, 2017年07月, 査読有り

  
• Toll-like receptor genetic variations in bone marrow transplantation

  Kaori Uchino; Shohei Mizuno; Aiko Sato-Otsubo; Yasuhito Nannya; Motonori Mizutani; Tomohiro Horio; Ichiro Hanamura; J. Luis Espinoza; Makoto Onizuka; Koichi Kashiwase; Yasuo Morishima; Takahiro Fukuda; Yoshihisa Kodera; Noriko Doki; Koichi Miyamura; Takehiko Mori; Seishi Ogawa; Akiyoshi Takami

  ONCOTARGET, 2017年07月, 査読有り

  
• Common Variable Immunodeficiency Caused by FANC Mutations

  Yujin Sekinaka; Noriko Mitsuiki; Kohsuke Imai; Miharu Yabe; Hiromasa Yabe; Kanako Mitsui-Sekinaka; Kenichi Honma; Masatoshi Takagi; Ayako Arai; Kenichi Yoshida; Yusuke Okuno; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Hideki Muramatsu; Seiji Kojima; Asuka Hira; Minoru Takata; Osamu Ohara; Seishi Ogawa; Tomohiro Morio; Shigeaki Nonoyama

  JOURNAL OF CLINICAL IMMUNOLOGY, 2017年07月, 査読有り

  
• Haploinsufficiency of TNFAIP3 (A20) by germline mutation is involved in autoimmune lymphoproliferative syndrome

  Masatoshi Takagi; Shohei Ogata; Hiroo Ueno; Kenichi Yoshida; Tzuwen Yeh; Akihiro Hoshino; Jinhua Piao; Motoy Yamashita; Mai Nanya; Tsubasa Okano; Michiko Kajiwara; Hirokazu Kanegane; Hideki Muramatsu; Yusuke Okuno; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Yuki Bando; Motohiro Kato; Yasuhide Hayashi; Satoru Miyano; Kohsuke Imai; Seishi Ogawa; Seiji Kojima; Tomohiro Morio

  JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017年06月, 査読有り

  
• Clinical significance of somatic mutation in unexplained blood cytopenia

  Luca Malcovati; Anna Galli; Erica Travaglino; Ilaria Ambaglio; Ettore Rizzo; Elisabetta Molteni; Chiara Elena; Virginia Valeria Ferretti; Silvia Catricala; Elisa Bono; Gabriele Todisco; Antonio Bianchessi; Elisa Rumi; Silvia Zibellini; Daniela Pietra; Emanuela Boveri; Clara Camaschella; Daniela Toniolo; Elli Papaemmanuil; Seishi Ogawa; Mario Cazzola

  BLOOD, 2017年06月, 査読有り

  
• Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA

  Itaru Kato; Yoko Nishinaka; Masahiro Nakamura; Ayse U. Akarca; Akira Niwa; Hiroki Ozawa; Kenichi Yoshida; Makiko Mori; Dapeng Wang; Makiko Morita; Hiroo Ueno; Yusuke Shiozawa; Yuichi Shiraishi; Satoru Miyano; Rajeev Gupta; Katsutsugu Umeda; Kenichiro Watanabe; Katsuyoshi Koh; Souichi Adachi; Toshio Heike; Megumu K. Saito; Masashi Sanada; Seishi Ogawa; Teresa Marafioti; Akira Watanabe; Tatsutoshi Nakahata; Tariq Enver

  BLOOD, 2017年06月, 査読有り

  
• The U2AF1(S34F) mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

  Bon Ham Yip; Violetta Steeples; Emmanouela Repapi; Richard N. Armstrong; Miriam Llorian; Swagata Roy; Jacqueline Shaw; Hamid Dolatshad; Stephen Taylor; Amit Verma; Matthias Bartenstein; Paresh Vyas; Nicholas C. P. Cross; Luca Malcovati; Mario Cazzola; Eva Hellstrom-Lindberg; Seishi Ogawa; Christopher W. J. Smith; Andrea Pellagatti; Jacqueline Boultwood

  JOURNAL OF CLINICAL INVESTIGATION, 2017年06月, 査読有り

  
• ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/RUNX1-RUNX1T1 and associated with a better prognosis

  Genki Yamato; Norio Shiba; Kenichi Yoshida; Yuichi Shiraishi; Yusuke Hara; Kentaro Ohki; Jun Okubo; Haruna Okuno; Kenichi Chiba; Hiroko Tanaka; Akitoshi Kinoshita; Hiroshi Moritake; Nobutaka Kiyokawa; Daisuke Tomizawa; Myoung-ja Park; Manabu Sotomatsu; Takashi Taga; Souichi Adachi; Akio Tawa; Keizo Horibe; Hirokazu Arakawa; Satoru Miyano; Seishi Ogawa; Yasuhide Hayashi

  GENES CHROMOSOMES & CANCER, 2017年05月, 査読有り

  
• BRCA1 alterations with additional defects in DNA damage response genes may confer chemoresistance to BRCA-like breast cancers treated with neoadjuvant chemotherapy

  Mamoru Takada; Shigenori Nagai; Masayuki Haruta; Ryuichi P. Sugino; Katsunori Tozuka; Hiroyuki Takei; Fumie Ohkubo; Kenichi Inoue; Masafumi Kurosumi; Masaru Miyazaki; Aiko Sato-Otsubo; Yusuke Sato; Seishi Ogawa; Yasuhiko Kaneko

  GENES CHROMOSOMES & CANCER, 2017年05月, 査読有り

  
• The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development

  Masaki Miyazaki; Kazuko Miyazaki; Kenian Chen; Yi Jin; Jacob Turner; Amanda J. Moore; Rintaro Saito; Kenichi Yoshida; Seishi Ogawa; Hans-Reimer Rodewald; Yin C. Lin; Hiroshi Kawamoto; Cornelis Murre

  IMMUNITY, 2017年05月, 査読有り

  
• Correction: Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.

  Ryutaro Uchi; Yusuke Takahashi; Atsushi Niida; Teppei Shimamura; Hidenari Hirata; Keishi Sugimachi; Genta Sawada; Takeshi Iwaya; Junji Kurashige; Yoshiaki Shinden; Tomohiro Iguchi; Hidetoshi Eguchi; Kenichi Chiba; Yuichi Shiraishi; Genta Nagae; Kenichi Yoshida; Yasunobu Nagata; Hiroshi Haeno; Hirofumi Yamamoto; Hideshi Ishii; Yuichiro Doki; Hisae Iinuma; Shin Sasaki; Satoshi Nagayama; Kazutaka Yamada; Shinichi Yachida; Mamoru Kato; Tatsuhiro Shibata; Eiji Oki; Hiroshi Saeki; Ken Shirabe; Yoshinao Oda; Yoshihiko Maehara; Shizuo Komune; Masaki Mori; Yutaka Suzuki; Ken Yamamoto; Hiroyuki Aburatani; Seishi Ogawa; Satoru Miyano; Koshi Mimori

  PLoS genetics, 2017年05月, 査読有り

  
• A TLR3-Specific Adjuvant Relieves Innate Resistance to PD-L1 Blockade without Cytokine Toxicity in Tumor Vaccine Immunotherapy

  Yohei Takeda; Keisuke Kataoka; Junya Yamagishi; Seishi Ogawa; Tsukasa Seya; Misako Matsumoto

  CELL REPORTS, 2017年05月, 査読有り

  この論文にアクセスする：

  
• Diagnostic challenge of Diamond-Blackfan anemia in mothers and children by whole-exome sequencing

  Takuya Ichimura; Kenichi Yoshida; Yusuke Okuno; Toshiaki Yujiri; Kozo Nagai; Masanori Nishi; Yuichi Shiraishi; Hiroo Ueno; Tsutomu Toki; Kenichi Chiba; Hiroko Tanaka; Hideki Muramatsu; Toshiro Hara; Hitoshi Kanno; Seiji Kojima; Satoru Miyano; Etsuro Ito; Seishi Ogawa; Shouichi Ohga

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2017年04月, 査読有り

  
• BCL6 locus is hypermethylated in angioimmunoblastic T-cell lymphoma

  Shoko Nishizawa; Mamiko Sakata-Yanagimoto; Keiichiro Hattori; Hideharu Muto; Tran Nguyen; Koji Izutsu; Kenichi Yoshida; Seishi Ogawa; Naoya Nakamura; Shigeru Chiba

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2017年04月, 査読有り

  
• Acquired expression of Cbl(Q367P) in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

  Yuichiro Nakata; Takeshi Ueda; Akiko Nagamachi; Norimasa Yamasaki; Ken-ichiro Ikeda; Yasuyuki Sera; Keiyo Takubo; Akinori Kanai; Hideaki Oda; Masashi Sanada; Seishi Ogawa; Kohichiro Tsuji; Yasuhiro Ebihara; Linda Wolff; Zen-ichiro Honda; Toshio Suda; Toshiya Inaba; Hiroaki Honda

  BLOOD, 2017年04月, 査読有り

  
• Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation

  Tetsuichi Yoshizato; Yasuhito Nannya; Yoshiko Atsuta; Yusuke Shiozawa; Yuka Iijima-Yamashita; Kenichi Yoshida; Yuichi Shiraishi; Hiromichi Suzuki; Yasunobu Nagata; Yusuke Sato; Nobuyuki Kakiuchi; Keitaro Matsuo; Makoto Onizuka; Keisuke Kataoka; Kenichi Chiba; Hiroko Tanaka; Hiroo Ueno; Masahiro M. Nakagawa; Bartlomiej Przychodzen; Claudia Haferlach; Wolfgang Kern; Kosuke Aoki; Hidehiro Itonaga; Yoshinobu Kanda; Mikkael A. Sekeres; Jaroslaw P. Maciejewski; Torsten Haferlach; Yasushi Miyazaki; Keizo Horibe; Masashi Sanada; Satoru Miyano; Hideki Makishima; Seishi Ogawa

  BLOOD, 2017年04月, 査読有り

  
• Clonal evolution in myelodysplastic syndromes

  Pedro da Silva-Coelho; Leonie I. Kroeze; Kenichi Yoshida; Theresia N. Koorenhof-Scheele; Ruth Knops; Louis T. van de Locht; Aniek O. de Graaf; Marion Massop; Sarah Sandmann; Martin Dugas; Marian J. Stevens-Kroef; Jaroslav Cermak; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Theo de Witte; Nicole M. A. Blijlevens; Petra Muus; Gerwin Huls; Bert A. van der Reijden; Seishi Ogawa; Joop H. Jansen

  NATURE COMMUNICATIONS, 2017年04月, 査読有り

  
• Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration.

  Michiko Mandai; Akira Watanabe; Yasuo Kurimoto; Yasuhiko Hirami; Chikako Morinaga; Takashi Daimon; Masashi Fujihara; Hiroshi Akimaru; Noriko Sakai; Yumiko Shibata; Motoki Terada; Yui Nomiya; Shigeki Tanishima; Masahiro Nakamura; Hiroyuki Kamao; Sunao Sugita; Akishi Onishi; Tomoko Ito; Kanako Fujita; Shin Kawamata; Masahiro J Go; Chikara Shinohara; Ken-Ichiro Hata; Masanori Sawada; Midori Yamamoto; Sachiko Ohta; Yasuo Ohara; Kenichi Yoshida; Junko Kuwahara; Yuko Kitano; Naoki Amano; Masafumi Umekage; Fumiyo Kitaoka; Azusa Tanaka; Chihiro Okada; Naoko Takasu; Seishi Ogawa; Shinya Yamanaka; Masayo Takahashi

  The New England journal of medicine, 2017年03月16日, 査読有り

  
• Metachronous anaplastic sarcoma of the kidney and thyroid follicular carcinoma as manifestations of DICER1 abnormalities

  Misa Yoshida; Satoshi Hamanoue; Masafumi Seki; Mio Tanaka; Kenichi Yoshida; Hiroaki Goto; Seishi Ogawa; Junko Takita; Yukichi Tanaka

  HUMAN PATHOLOGY, 2017年03月, 査読有り

  
• Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia

  Fumika Ikeda; Kenichi Yoshida; Tsutomu Toki; Tamayo Uechi; Shiori Ishida; Yukari Nakajima; Yoji Sasahara; Yusuke Okuno; Rika Kanezaki; Kiminori Terui; Takuya Kamio; Akie Kobayashi; Takashi Fujita; Aiko Sato-Otsubo; Yuichi Shiraishi; Hiroko Tanaka; Kenichi Chiba; Hideki Muramatsu; Hitoshi Kanno; Shouichi Ohga; Akira Ohara; Seiji Kojima; Naoya Kenmochi; Satoru Miyano; Seishi Ogawa; Etsuro Ito

  HAEMATOLOGICA, 2017年03月, 査読有り

  
• Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene

  Scott A. Nadeau; Wei An; Bhopal C. Mohapatra; Insha Mushtaq; Timothy A. Bielecki; Haitao Luan; Neha Zutshi; Gulzar Ahmad; Matthew D. Storck; Masashi Sanada; Seishi Ogawa; Vimla Band; Hamid Band

  JOURNAL OF BIOLOGICAL CHEMISTRY, 2017年03月, 査読有り

  
• Copy number analysis identifies tumor suppressive lncRNAs in human osteosarcoma

  Jianjun Xie; Dechen Lin; Dhong Hyun Tony Lee; Jennifer Akunowicz; Marc Hansen; Carl Miller; Masashi Sanada; Motohiro Kato; Tadayuki Akagi; Norihiko Kawamata; Seishi Ogawa; H. Phillip Koeffler

  INTERNATIONAL JOURNAL OF ONCOLOGY, 2017年03月, 査読有り

  
• Novel lincRNA SLINKY is a prognostic biomarker in kidney cancer

  Xue Gong; Zurab Siprashvili; Okyaz Eminaga; Zhewei Shen; Yusuke Sato; Haruki Kume; Yukio Homma; Seishi Ogawa; Paul A. Khavari; Jonathan R. Pollack; James D. Brooks

  ONCOTARGET, 2017年03月, 査読有り

  
• Dynamics of clonal evolution in myelodysplastic syndromes

  Hideki Makishima; Tetsuichi Yoshizato; Kenichi Yoshida; Mikkael A. Sekeres; Tomas Radivoyevitch; Hiromichi Suzuki; Bartlomiej Przychodzen; Yasunobu Nagata; Manja Meggendorfer; Masashi Sanada; Yusuke Okuno; Cassandra Hirsch; Teodora Kuzmanovic; Yusuke Sato; Aiko Sato-Otsubo; Thomas LaFramboise; Naoko Hosono; Yuichi Shiraishi; Kenichi Chiba; Claudia Haferlach; Wolfgang Kern; Hiroko Tanaka; Yusuke Shiozawa; Ines Gomez-Segui; Holleh D. Husseinzadeh; Swapna Thota; Kathryn M. Guinta; Brittney Dienes; Tsuyoshi Nakamaki; Shuichi Miyawaki; Yogen Saunthararajah; Shigeru Chiba; Satoru Miyano; Lee-Yung Shih; Torsten Haferlach; Seishi Ogawa; Jaroslaw P. Maciejewski

  NATURE GENETICS, 2017年02月, 査読有り

  
• Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia

  Ling-Wen Ding; Qiao-Yang Sun; Kar-Tong Tan; Wenwen Chien; Anand Mayakonda Thippeswamy; Allen Eng Juh Yeoh; Norihiko Kawamata; Yasunobu Nagata; Jin-Fen Xiao; Xin-Yi Loh; De-Chen Lin; Manoj Garg; Yan-Yi Jiang; Liang Xu; Su-Lin Lim; Li-Zhen Liu; Vikas Madan; Masashi Sanada; Lucia Torres Fernandez; Hema Preethi; Michael Lill; Hagop M. Kantarjian; Steven M. Kornblau; Satoru Miyano; Der-Cherng Liang; Seishi Ogawa; Lee-Yung Shih; Henry Yang; H. Phillip Koeffler

  CANCER RESEARCH, 2017年01月, 査読有り

  
• Recurrent genetic defects on chromosome 5q in myeloid neoplasms

  Naoko Hosono; Hideki Makishima; Reda Mahfouz; Bartlomiej Przychodzen; Kenichi Yoshida; Andres Jerez; Thomas LaFramboise; Chantana Polprasert; Michael J. Clemente; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Masashi Sanada; Edward Cui; Amit K. Verma; Michael A. McDevitt; Alan F. List; Yogen Saunthararajah; Mikkael A. Sekeres; Jacqueline Boultwood; Seishi Ogawa; Jaroslaw P. Maciejewski

  ONCOTARGET, 2017年01月, 査読有り

  この論文にアクセスする：

  
• Partial monosomy of 10p and duplication of another chromosome in two patients

  Sayaka Ohta; Tsuyoshi Isojima; Yoko Mizuno; Motohiro Kato; Masakazu Mimaki; Masafumi Seki; Yusuke Sato; Seishi Ogawa; Junko Takita; Sachiko Kitanaka; Akira Oka

  PEDIATRICS INTERNATIONAL, 2017年01月, 査読有り

  
• A novel prognostic model incorporating genetic profiling for myelodysplastic syndromes.

  Nagata Y; Ogawa S

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2017年, 査読有り

  
• Novel mechanism of immune evasion in cancer via structural variations of the PD-L1 gene.

  Ogawa S

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2017年, 査読有り

  
• Phosphatase and tensin homolog (PTEN) mutation can cause activated phosphatidylinositol 3-kinase δ syndrome-like immunodeficiency.

  Tsujita Y; Mitsui-Sekinaka K; Imai K; Yeh TW; Mitsuiki N; Asano T; Ohnishi H; Kato Z; Sekinaka Y; Zaha K; Kato T; Okano T; Takashima T; Kobayashi K; Kimura M; Kunitsu T; Maruo Y; Kanegane H; Takagi M; Yoshida K; Okuno Y; Muramatsu H; Shiraishi Y; Chiba K; Tanaka H; Miyano S; Kojima S; Ogawa S; Ohara O; Okada S; Kobayashi M; Morio T; Nonoyama S

  The Journal of allergy and clinical immunology, 2016年12月, 査読有り

  
• TERT promoter mutations and chromosome 8p loss are characteristic of nonalcoholic fatty liver disease-related hepatocellular carcinoma

  Soo Ki Kim; Yoshihide Ueda; Etsuro Hatano; Nobuyuki Kakiuchi; Haruhiko Takeda; Tomoyuki Goto; Takahiro Shimizu; Kenichi Yoshida; Yoshihiro Ikura; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Shinji Uemoto; Tsutomu Chiba; Seishi Ogawa; Hiroyuki Marusawa

  INTERNATIONAL JOURNAL OF CANCER, 2016年12月, 査読有り

  
• Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

  Larry Mansouri; Daniel Noerenberg; Emma Young; Elena Mylonas; Maysaa Abdulla; Mareike Frick; Fazila Asmar; Viktor Ljungstroem; Markus Schneider; Kenichi Yoshida; Aron Skaftason; Tatjana Pandzic; Blanca Gonzalez; Anna Tasidou; Nils Waldhueter; Alfredo Rivas-Delgado; Maria Angelopoulou; Marita Ziepert; Christopher Maximilian Arends; Lucile Couronne; Dido Lenze; Claudia D. Baldus; Christian Bastard; Jessica Okosun; Jude Fitzgibbon; Bernd Doerken; Hans G. Drexler; Damien Roos-Weil; Clemens A. Schmitt; Helga D. Munch-Petersen; Thorsten Zenz; Martin-Leo Hansmann; Jonathan C. Strefford; Gunilla Enblad; Olivier A. Bernard; Elisabeth Ralfkiaer; Martin Erlanson; Penelope Korkolopoulou; Magnus Hultdin; Theodora Papadaki; Kirsten Gronbaek; Armando Lopez-Guillermo; Seishi Ogawa; Ralf Kuppers; Kostas Stamatopoulos; Niki Stavroyianni; George Kanellis; Andreas Rosenwald; Elias Campo; Rose-Marie Amini; German Ott; Theodoros P. Vassilakopoulos; Michael Hummel; Richard Rosenquist; Frederik Damm

  BLOOD, 2016年12月, 査読有り

  
• Variegated RHOA mutations in human cancers

  Keisuke Kataoka; Seishi Ogawa

  EXPERIMENTAL HEMATOLOGY, 2016年12月, 査読有り

  
• Somatic mosaicism in chronic myeloid leukemia in remission

  Kinuko Mitani; Yasunobu Nagata; Ko Sasaki; Kenichi Yoshida; Kenichi Chiba; Hiroko Tanaka; Yuichi Shiraishi; Satoru Miyano; Hideki Makishima; Yukitsugu Nakamura; Yuka Nakamura; Motoshi Ichikawa; Seishi Ogawa

  BLOOD, 2016年12月, 査読有り

  
• Regeneration of CD8αβ T Cells from T-cell-Derived iPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity.

  Maeda T; Nagano S; Ichise H; Kataoka K; Yamada D; Ogawa S; Koseki H; Kitawaki T; Kadowaki N; Takaori-Kondo A; Masuda K; Kawamoto H

  Cancer research, 2016年12月, 査読有り

  
• The phenotype and clinical course of Japanese Fanconi Anaemia infants is influenced by patient, but not maternal ALDH2 genotype

  Miharu Yabe; Hiromasa Yabe; Tsuyoshi Morimoto; Akiko Fukumura; Keisuke Ohtsubo; Takashi Koike; Kenichi Yoshida; Seishi Ogawa; Etsuro Ito; Yusuke Okuno; Hideki Muramatsu; Seiji Kojima; Keitaro Matsuo; Asuka Hira; Minoru Takata

  BRITISH JOURNAL OF HAEMATOLOGY, 2016年11月, 査読有り

  
• Whole-exome sequencing reveals the spectrum of gene mutations and the clonal evolution patterns in paediatric acute myeloid leukaemia

  Norio Shiba; Kenichi Yoshida; Yuichi Shiraishi; Yusuke Okuno; Genki Yamato; Yusuke Hara; Yasunobu Nagata; Kenichi Chiba; Hiroko Tanaka; Kiminori Terui; Motohiro Kato; Myoung-ja Park; Kentaro Ohki; Akira Shimada; Junko Takita; Daisuke Tomizawa; Kazuko Kudo; Hirokazu Arakawa; Souichi Adachi; Takashi Taga; Akio Tawa; Etsuro Ito; Keizo Horibe; Masashi Sanada; Satoru Miyano; Seishi Ogawa; Yasuhide Hayashi

  BRITISH JOURNAL OF HAEMATOLOGY, 2016年11月, 査読有り

  
• Genomic analysis of clonal origin of Langerhans cell histiocytosis following acute lymphoblastic leukaemia

  Motohiro Kato; Masafumi Seki; Kenichi Yoshida; Yusuke Sato; Ryo Oyama; Yuki Arakawa; Hiroshi Kishimoto; Tomohiko Taki; Masaharu Akiyama; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Noriko Mitsuiki; Michiko Kajiwara; Shuki Mizutani; Masashi Sanada; Satoru Miyano; Seishi Ogawa; Katsuyoshi Koh; Junko Takita

  BRITISH JOURNAL OF HAEMATOLOGY, 2016年10月, 査読有り

  
• Clinical significance and origin of leukocytes that lack HLA-A allele expression in patients with acquired aplastic anemia

  Hiroyuki Maruyama; Takamasa Katagiri; Koichi Kashiwase; Takashi Shiina; Aiko Sato-Otsubo; Yoshitaka Zaimoku; Kana Maruyama; Kohei Hosokawa; Ken Ishiyama; Hirohito Yamazaki; Hidetoshi Inoko; Seishi Ogawa; Shinji Nakao

  EXPERIMENTAL HEMATOLOGY, 2016年10月, 査読有り

  
• Truncation and microdeletion of EVC/EVC2 with missense mutation of EFCAB7 in Ellis-van Creveld syndrome

  Tran Quynh Nhu Nguyen; Makiko Saitoh; Huu Tung Trinh; Nguyen Minh Thien Doan; Yoko Mizuno; Masafumi Seki; Yusuke Sato; Seishi Ogawa; Masashi Mizuguchi

  CONGENITAL ANOMALIES, 2016年09月, 査読有り

  
• Single cell genotyping of exome sequencing-identified mutations to characterize the clonal composition and evolution of inv(16) AML in a CBL mutated clonal hematopoiesis

  Christoph Niemoeller; Nathalie Renz; Sabine Bleul; Nadja Blagitko-Dorfs; Christine Greil; Kenichi Yoshida; Dietmar Pfeifer; Marie Follo; Justus Duyster; Rainer Claus; Seishi Ogawa; Michael Luebbert; Heiko Becker

  LEUKEMIA RESEARCH, 2016年08月, 査読有り

  
• PIEZO1 gene mutation in a Japanese family with hereditary high phosphatidylcholine hemolytic anemia and hemochromatosis-induced diabetes mellitus

  Shinsaku Imashuku; Hideki Muramatsu; Takashi Sugihara; Yusuke Okuno; Xinan Wang; Kenichi Yoshida; Ayako Kato; Koichi Kato; Yasuaki Tatsumi; Ai Hattori; Shinya Kita; Keishi Oe; Atsushi Sueyoshi; Takeshi Usui; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Seishi Ogawa; Seiji Kojima; Hitoshi Kanno

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2016年07月, 査読有り

  
• Clonal hematopoiesis in acquired aplastic anemia

  Seishi Ogawa

  BLOOD, 2016年07月, 査読有り

  
• Adults with germline CBL mutation complicated with juvenile myelomonocytic leukemia at infancy

  Michiko Muraoka; Chiho Okuma; Kiichiro Kanamitsu; Hisashi Ishida; Yui Kanazawa; Kana Washio; Masafumi Seki; Motohiro Kato; Junko Takita; Yusuke Sato; Seishi Ogawa; Hirokazu Tsukahara; Megumi Oda; Akira Shimada

  JOURNAL OF HUMAN GENETICS, 2016年06月, 査読有り

  
• Aberrant PD-L1 expression through 3 '-UTR disruption in multiple cancers

  Keisuke Kataoka; Yuichi Shiraishi; Yohei Takeda; Seiji Sakata; Misako Matsumoto; Seiji Nagano; Takuya Maeda; Yasunobu Nagata; Akira Kitanaka; Seiya Mizuno; Hiroko Tanaka; Kenichi Chiba; Satoshi Ito; Yosaku Watatani; Nobuyuki Kakiuchi; Hiromichi Suzuki; Tetsuichi Yoshizato; Kenichi Yoshida; Masashi Sanada; Hidehiro Itonaga; Yoshitaka Imaizumi; Yasushi Totoki; Wataru Munakata; Hiromi Nakamura; Natsuko Hama; Kotaro Shide; Yoko Kubuki; Tomonori Hidaka; Takuro Kameda; Kyoko Masuda; Nagahiro Minato; Koichi Kashiwase; Koji Izutsu; Akifumi Takaori-Kondo; Yasushi Miyazaki; Satoru Takahashi; Tatsuhiro Shibata; Hiroshi Kawamoto; Yoshiki Akatsuka; Kazuya Shimoda; Kengo Takeuchi; Tsukasa Seya; Satoru Miyano; Seishi Ogawa

  NATURE, 2016年06月, 査読有り

  
• Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population.

  Sawada G; Niida A; Uchi R; Hirata H; Shimamura T; Suzuki Y; Shiraishi Y; Chiba K; Imoto S; Takahashi Y; Iwaya T; Sudo T; Hayashi T; Takai H; Kawasaki Y; Matsukawa T; Eguchi H; Sugimachi K; Tanaka F; Suzuki H; Yamamoto K; Ishii H; Shimizu M; Yamazaki H; Yamazaki M; Tachimori Y; Kajiyama Y; Natsugoe S; Fujita H; Mafune K; Tanaka Y; Kelsell DP; Scott CA; Tsuji S; Yachida S; Shibata T; Sugano S; Doki Y; Akiyama T; Aburatani H; Ogawa S; Miyano S; Mori M; Mimori K

  Gastroenterology, 2016年05月, 査読有り

  
• ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia

  Nobuto Arashiki; Yuichi Takakuwa; Narla Mohandas; John Hale; Kenichi Yoshida; Hiromi Ogura; Taiju Utsugisawa; Shouichi Ohga; Satoru Miyano; Seishi Ogawa; Seiji Kojima; Hitoshi Kanno

  HAEMATOLOGICA, 2016年05月, 査読有り

  
• Neoantigen Load, Antigen Presentation Machinery, and Immune Signatures Determine Prognosis in Clear Cell Renal Cell Carcinoma

  Hirokazu Matsushita; Yusuke Sato; Takahiro Karasaki; Tohru Nakagawa; Haruki Kume; Seishi Ogawa; Yukio Homma; Kazuhiro Kakimi

  CANCER IMMUNOLOGY RESEARCH, 2016年05月, 査読有り

  
• High-risk HLA alleles for severe acute graft-versus-host disease and mortality in unrelated donor bone marrow transplantation

  Satoko Morishima; Koichi Kashiwase; Keitaro Matsuo; Fumihiro Azuma; Toshio Yabe; Aiko Sato-Otsubo; Seishi Ogawa; Takashi Shiina; Masahiro Satake; Hiroh Saji; Shunichi Kato; Yoshihisa Kodera; Takehiko Sasazuki; Yasuo Morishima

  HAEMATOLOGICA, 2016年04月, 査読有り

  
• [Genetic landscape of adult T-cell leukemia/lymphoma].

  Kataoka K; Ogawa S

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2016年04月, 査読有り

  
• Impact of SNP array karyotyping on the diagnosis and the outcome of chronic myelomonocytic leukemia with low risk cytogenetic features or no metaphases

  Laura Palomo; Blanca Xicoy; Olga Garcia; Mar Mallo; Vera Adema; Marta Cabezon; Montse Arnan; Helena Pomares; Maria Jose Larrayoz; Maria Jose Calasanz; Jaroslaw P. Maciejewski; Dayong Huang; Lee-Yung Shih; Seishi Ogawa; Jose Cervera; Esperanza Such; Rosa Coll; Javier Grau; Francesc Sole; Lurdes Zamora

  AMERICAN JOURNAL OF HEMATOLOGY, 2016年02月, 査読有り

  
• Variegated RHOA mutations in adult T-cell leukemia/lymphoma

  Yasunobu Nagata; Kenji Kontani; Terukazu Enami; Keisuke Kataoka; Ryohei Ishii; Yasushi Totoki; Tatsuki R. Kataoka; Masahiro Hirata; Kazuhiro Aoki; Kazumi Nakano; Akira Kitanaka; Mamiko Sakata-Yanagimoto; Sachiko Egami; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Yusuke Shiozawa; Tetsuichi Yoshizato; Hiromichi Suzuki; Ayana Kon; Kenichi Yoshida; Yusuke Sato; Aiko Sato-Otsubo; Masashi Sanada; Wataru Munakata; Hiromi Nakamura; Natsuko Hama; Satoru Miyano; Osamu Nureki; Tatsuhiro Shibata; Hironori Haga; Kazuya Shimoda; Toshiaki Katada; Shigeru Chiba; Toshiki Watanabe; Seishi Ogawa

  BLOOD, 2016年02月, 査読有り

  
• Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.

  Ryutaro Uchi; Yusuke Takahashi; Atsushi Niida; Teppei Shimamura; Hidenari Hirata; Keishi Sugimachi; Genta Sawada; Takeshi Iwaya; Junji Kurashige; Yoshiaki Shinden; Tomohiro Iguchi; Hidetoshi Eguchi; Kenichi Chiba; Yuichi Shiraishi; Genta Nagae; Kenichi Yoshida; Yasunobu Nagata; Hiroshi Haeno; Hirofumi Yamamoto; Hideshi Ishii; Yuichiro Doki; Hisae Iinuma; Shin Sasaki; Satoshi Nagayama; Kazutaka Yamada; Shinichi Yachida; Mamoru Kato; Tatsuhiro Shibata; Eiji Oki; Hiroshi Saeki; Ken Shirabe; Yoshinao Oda; Yoshihiko Maehara; Shizuo Komune; Masaki Mori; Yutaka Suzuki; Ken Yamamoto; Hiroyuki Aburatani; Seishi Ogawa; Satoru Miyano; Koshi Mimori

  PLoS genetics, 2016年02月, 査読有り

  
• Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

  Jane Merlevede; Nathalie Droin; Tingting Qin; Kristen Meldi; Kenichi Yoshida; Margot Morabito; Emilie Chautard; Didier Auboeuf; Pierre Fenaux; Thorsten Braun; Raphael Itzykson; Stephane de Botton; Bruno Quesnel; Therese Commes; Eric Jourdan; William Vainchenker; Olivier Bernard; Noemie Pata-Merci; Stephanie Solier; Velimir Gayevskiy; Marcel E. Dinger; Mark J. Cowley; Dorothee Selimoglu-Buet; Vincent Meyer; Francois Artiguenave; Jean-Francois Deleuze; Claude Preudhomme; Michael R. Stratton; Ludmil B. Alexandrov; Eric Padron; Seishi Ogawa; Serge Koscielny; Maria Figueroa; Eric Solary

  NATURE COMMUNICATIONS, 2016年02月, 査読有り

  この論文にアクセスする：

  
• Induction of HLA-B*40:02-restricted T cells possessing cytotoxic and suppressive functions against haematopoietic progenitor cells from a patient with severe aplastic anaemia

  Yoko Inaguma; Yoshiki Akatsuka; Kohei Hosokawa; Hiroyuki Maruyama; Akinao Okamoto; Takamasa Katagiri; Keiko Shiraishi; Yuko Murayama; Sachiko Tsuzuki-Iba; Yuuki Mizutani; Chikako Nishii; Naoki Yamamoto; Ayako Demachi-Okamura; Kiyotaka Kuzushima; Seishi Ogawa; Nobuhiko Emi; Shinji Nakao

  BRITISH JOURNAL OF HAEMATOLOGY, 2016年01月, 査読有り

  
• ALDH2 polymorphism in patients with Diamond-Blackfan anemia in Japan

  Fumika Ikeda; Tsutomu Toki; Rika Kanezaki; Kiminori Terui; Kenichi Yoshida; Hitoshi Kanno; Shouichi Ohga; Akira Ohara; Seiji Kojima; Seishi Ogawa; Etsuro Ito

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2016年01月, 査読有り

  
• Gene mutations in myelodysplastic syndromes.

  Makishima H; Ogawa S

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2016年, 査読有り

  
• Genetic biomarkers for PD-1/PD-L1 blockade therapy

  Keisuke Kataoka; Seishi Ogawa

  Oncoscience, 2016年, 査読有り

  
• Genome-wide surveillance of mismatched alleles for graft-versus-host disease in stem cell transplantation

  Aiko Sato-Otsubo; Yasuhito Nannya; Koichi Kashiwase; Makoto Onizuka; Fumihiro Azuma; Yoshiki Akatsuka; Yasuko Ogino; Masahiro Satake; Masashi Sanada; Shigeru Chiba; Hiroh Saji; Hidetoshi Inoko; Giulia C. Kennedy; Ken Yamamoto; Satoko Morishima; Yasuo Morishima; Yoshihisa Kodera; Takehiko Sasazuki; Seishi Ogawa

  BLOOD, 2015年12月, 査読有り

  
• Genomic landscape of liposarcoma

  Deepika Kanojia; Yasunobu Nagata; Manoj Garg; Dhong Hyun Lee; Aiko Sato; Kenichi Yoshida; Yusuke Sato; Masashi Sanada; Anand Mayakonda; Christoph Bartenhagen; Hans-Ulrich Klein; Ngan B. Doan; Jonathan W. Said; S. Mohith; Swetha Gunasekar; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Ola Myklebost; Henry Yang; Martin Dugas; Leonardo A. Meza-Zepeda; Allan W. Silberman; Charles Forscher; Jeffrey W. Tyner; Seishi Ogawa; H. Phillip Koeffler

  ONCOTARGET, 2015年12月, 査読有り

  この論文にアクセスする：

  
• Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia

  Hirotoshi Sakaguchi; Hideki Muramatsu; Yusuke Okuno; Hideki Makishima; Yinyan Xu; Yoko Furukawa-Hibi; Xinan Wang; Atsushi Narita; Kenichi Yoshida; Yuichi Shiraishi; Sayoko Doisaki; Nao Yoshida; Asahito Hama; Yoshiyuki Takahashi; Kiyofumi Yamada; Satoru Miyano; Seishi Ogawa; Jaroslaw P. Maciejewski; Seiji Kojima

  PLOS ONE, 2015年12月, 査読有り

  この論文にアクセスする：

  
• Clinical and genetic features of dyskeratosis congenita, cryptic dyskeratosis congenita, and Hoyeraal-Hreidarsson syndrome in Japan

  Hiroki Yamaguchi; Hirotoshi Sakaguchi; Kenichi Yoshida; Miharu Yabe; Hiromasa Yabe; Yusuke Okuno; Hideki Muramatsu; Yoshiyuki Takahashi; Shunsuke Yui; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Koiti Inokuchi; Etsuro Ito; Seishi Ogawa; Seiji Kojima

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2015年11月, 査読有り

  
• Integrated molecular analysis of adult T cell leukemia/lymphoma

  Keisuke Kataoka; Yasunobu Nagata; Akira Kitanaka; Yuichi Shiraishi; Teppei Shimamura; Jun-Ichirou Yasunaga; Yasushi Totoki; Kenichi Chiba; Aiko Sato-Otsubo; Genta Nagae; Ryohei Ishii; Satsuki Muto; Shinichi Kotani; Yosaku Watatani; June Takeda; Masashi Sanada; Hiroko Tanaka; Hiromichi Suzuki; Yusuke Sato; Yusuke Shiozawa; Tetsuichi Yoshizato; Kenichi Yoshida; Hideki Makishima; Masako Iwanaga; Guangyong Ma; Kisato Nosaka; Masakatsu Hishizawa; Hidehiro Itonaga; Yoshitaka Imaizumi; Wataru Munakata; Hideaki Ogasawara; Toshitaka Sato; Ken Sasai; Kenzo Muramoto; Marina Penova; Takahisa Kawaguchi; Hiromi Nakamura; Natsuko Hama; Kotaro Shide; Yoko Kubuki; Tomonori Hidaka; Takuro Kameda; Tsuyoshi Nakamaki; Ken Ishiyama; Shuichi Miyawaki; Sung-Soo Yoon; Kensei Tobinai; Yasushi Miyazaki; Akifumi Takaori-Kondo; Fumihiko Matsuda; Kengo Takeuchi; Osamu Nureki; Hiroyuki Aburatani; Toshiki Watanabe; Tatsuhiro Shibata; Masao Matsuoka; Satoru Miyano; Kazuya Shimoda; Seishi Ogawa

  NATURE GENETICS, 2015年11月, 査読有り

  
• Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse

  Manoj Garg; Yasunobu Nagata; Deepika Kanojia; Anand Mayakonda; Kenichi Yoshida; Sreya Haridas Keloth; Zhi Jiang Zang; Yusuke Okuno; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Ling-Wen Ding; Tamara Alpermann; Qiao-Yang Sun; De-Chen Lin; Wenwen Chien; Vikas Madan; Li-Zhen Liu; Kar-Tong Tan; Abhishek Sampath; Subhashree Venkatesan; Koiti Inokuchi; Satoshi Wakita; Hiroki Yamaguchi; Wee Joo Chng; Shirley-Kow Yin Kham; Allen Eng-Juh Yeoh; Masashi Sanada; Joanna Schiller; Karl-Anton Kreuzer; Steven M. Kornblau; Hagop M. Kantarjian; Torsten Haferlach; Michael Lill; Ming-Chung Kuo; Lee-Yung Shih; Igor-Wolfgang Blau; Olga Blau; Henry Yang; Seishi Ogawa; H. Phillip Koeffler

  BLOOD, 2015年11月, 査読有り

  
• GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies

  Xinan Wang; Hideki Muramatsu; Yusuke Okuno; Hirotoshi Sakaguchi; Kenichi Yoshida; Nozomu Kawashima; Yinyan Xu; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Shoji Saito; Yozo Nakazawa; Taro Masunari; Tadashi Hirose; Shaimaa Elmahdi; Atsushi Narita; Sayoko Doisaki; Olfat Ismael; Hideki Makishima; Asahito Hama; Satoru Miyano; Yoshiyuki Takahashi; Seishi Ogawa; Seiji Kojima

  HAEMATOLOGICA, 2015年10月, 査読有り

  
• Late-Onset Combined Immunodeficiency with a Novel IL2RG Mutation and Probable Revertant Somatic Mosaicism

  Yusuke Okuno; Akihiro Hoshino; Hideki Muramatsu; Nozomu Kawashima; Xinan Wang; Kenichi Yoshida; Taizo Wada; Masaharu Gunji; Tomoko Toma; Tamaki Kato; Yuichi Shiraishi; Atsuko Iwata; Toshinori Hori; Toshiyuki Kitoh; Kenichi Chiba; Hiroko Tanaka; Masashi Sanada; Yoshiyuki Takahashi; Shigeaki Nonoyama; Masafumi Ito; Satoru Miyano; Seishi Ogawa; Seiji Kojima; Hirokazu Kanegane

  JOURNAL OF CLINICAL IMMUNOLOGY, 2015年10月, 査読有り

  
• Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia.

  Young NS; Ogawa S

  The New England journal of medicine, 2015年10月, 査読有り

  
• Adverse prognostic effect of homozygous TET2 mutation on the relapse risk of acute myeloid leukemia in patients of normal karyotype

  Jae-Sook Ahn; Hyeoung-Joon Kim; Yeo-Kyeoung Kim; Sung-Hoon Jung; Deok-Hwan Yang; Je-Jung Lee; Il-Kwon Lee; Nan Young Kim; Mark D. Minden; Chul Won Jung; Jun-Ho Jang; Hee Je Kim; Joon Ho Moon; Sang Kyun Sohn; Jong-Ho Won; Sung-Hyun Kim; Namshin Kim; Kenichi Yoshida; Seishi Ogawa; Dennis Dong Hwan Kim

  HAEMATOLOGICA, 2015年09月, 査読有り

  
• Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice

  Takafumi Toyohara; Shin-lchi Mae; Shin-lchi Sueta; Tatsuyuki Inoue; Yukiko Yamagishi; Tatsuya Kawamoto; Tomoko Kasahara; Azusa Hoshina; Taro Toyoda; Hiromi Tanaka; Toshikazu Araoka; Aiko Sato-Otsubo; Kazutoshi Takahashi; Yasunori Sato; Noboru Yamaji; Seishi Ogawa; Shinya Yamanaka; Kenji Osafune

  STEM CELLS TRANSLATIONAL MEDICINE, 2015年09月, 査読有り

  この論文にアクセスする：

  
• BRCC3 mutations in myeloid neoplasms

  Dayong Huang; Yasunobu Nagata; Vera Grossmann; Tomas Radivoyevitch; Yusuke Okuno; Genta Nagae; Naoko Hosono; Susanne Schnittger; Masashi Sanada; Bartlomiej Przychodzen; Ayana Kon; Chantana Polprasert; Wenyi Shen; Michael J. Clemente; James G. Phillips; Tamara Alpermann; Kenichi Yoshida; Niroshan Nadarajah; Mikkael A. Sekeres; Kevin Oakley; Nhu Nguyen; Yuichi Shiraishi; Yusuke Shiozawa; Kenichi Chiba; Hiroko Tanaka; H. Phillip Koeffler; Hans-Ulrich Klein; Martin Dugas; Hiroyuki Aburatani; Satoru Miyano; Claudia Haferlach; Wolfgang Kern; Torsten Haferlach; Yang Du; Seishi Ogawa; Hideki Makishima

  HAEMATOLOGICA, 2015年08月, 査読有り

  
• Somatic Mosaicism for a NRAS Mutation Associates with Disparate Clinical Features in RAS-associated Leukoproliferative Disease: a Report of Two Cases

  Mitsutaka Shiota; Xi Yang; Mei Kubokawa; Tatsuya Morishima; Kuniaki Tanaka; Masamitsu Mikami; Kenichi Yoshida; Masako Kikuchi; Kazushi Izawa; Ryuta Nishikomori; Yusuke Okuno; Xian Wang; Hirotoshi Sakaguchi; Hideki Muramatsu; Seiji Kojima; Satoru Miyano; Seishi Ogawa; Masatoshi Takagi; Daisuke Hata; Hirokazu Kanegane

  JOURNAL OF CLINICAL IMMUNOLOGY, 2015年07月, 査読有り

  
• Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

  T. Yoshizato; B. Dumitriu; K. Hosokawa; H. Makishima; K. Yoshida; D. Townsley; A. Sato-Otsubo; Y. Sato; D. Liu; H. Suzuki; C. O. Wu; Y. Shiraishi; M. J. Clemente; K. Kataoka; Y. Shiozawa; Y. Okuno; K. Chiba; H. Tanaka; Y. Nagata; T. Katagiri; A. Kon; M. Sanada; P. Scheinberg; S. Miyano; J. P. Maciejewski; S. Nakao; N. S. Young; S. Ogawa

  NEW ENGLAND JOURNAL OF MEDICINE, 2015年07月, 査読有り

  この論文にアクセスする：

  
• Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma

  Masafumi Seki; Riki Nishimura; Kenichi Yoshida; Teppei Shimamura; Yuichi Shiraishi; Yusuke Sato; Motohiro Kato; Kenichi Chiba; Hiroko Tanaka; Noriko Hoshino; Genta Nagae; Yusuke Shiozawa; Yusuke Okuno; Hajime Hosoi; Yukichi Tanaka; Hajime Okita; Mitsuru Miyachi; Ryota Souzaki; Tomoaki Taguchi; Katsuyoshi Koh; Ryoji Hanada; Keisuke Kato; Yuko Nomura; Masaharu Akiyama; Akira Oka; Takashi Igarashi; Satoru Miyano; Hiroyuki Aburatani; Yasuhide Hayashi; Seishi Ogawa; Junko Takita

  NATURE COMMUNICATIONS, 2015年07月, 査読有り

  この論文にアクセスする：

  
• [Genetic analysis of hereditary hematological disorders: overview].

  Yoshida K; Ogawa S

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2015年07月, 査読有り

  
• TCEB1-mutated renal cell carcinoma: a distinct genomic and morphological subtype

  A. Ari Hakimi; Satish K. Tickoo; Anders Jacobsen; Judy Sarungbam; John P. Sfakianos; Yusuke Sato; Teppei Morikawa; Haruki Kume; Masashi Fukayama; Yukio Homma; Ying-Bei Chen; Alexander I. Sankin; Roy Mano; Jonathan A. Coleman; Paul Russo; Seishi Ogawa; Chris Sander; James J. Hsieh; Victor E. Reuter

  MODERN PATHOLOGY, 2015年06月, 査読有り

  
• Mutations in the Gene Encoding the E2 Conjugating Enzyme UBE2T Cause Fanconi Anemia

  Asuka Hira; Kenichi Yoshida; Koichi Sato; Yusuke Okuno; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Akira Shimamoto; Hidetoshi Tahara; Etsuro Ito; Seiji Kojima; Hitoshi Kurumizaka; Seishi Ogawa; Minoru Takata; Hiromasa Yabe; Miharu Yabe

  AMERICAN JOURNAL OF HUMAN GENETICS, 2015年06月, 査読有り

  
• Genome-Wide Analysis of Ocular Adnexal Lymphoproliferative Disorders Using High-Resolution Single Nucleotide Polymorphism Array

  Hiroki Takahashi; Yoshihiko Usui; Shunichiro Ueda; Naoyuki Yamakawa; Aiko Sato-Otsubo; Yusuke Sato; Seishi Ogawa; Hiroshi Goto

  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2015年06月, 査読有り

  
• Mutational landscape and clonal architecture in grade II and III gliomas

  Hiromichi Suzuki; Kosuke Aoki; Kenichi Chiba; Yusuke Sato; Yusuke Shiozawa; Yuichi Shiraishi; Teppei Shimamura; Atsushi Niida; Kazuya Motomura; Fumiharu Ohka; Takashi Yamamoto; Kuniaki Tanahashi; Melissa Ranjit; Toshihiko Wakabayashi; Tetsuichi Yoshizato; Keisuke Kataoka; Kenichi Yoshida; Yasunobu Nagata; Aiko Sato-Otsubo; Hiroko Tanaka; Masashi Sanada; Yutaka Kondo; Hideo Nakamura; Masahiro Mizoguchi; Tatsuya Abe; Yoshihiro Muragaki; Reiko Watanabe; Ichiro Ito; Satoru Miyano; Atsushi Natsume; Seishi Ogawa

  NATURE GENETICS, 2015年05月, 査読有り

  
• Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms

  Chantana Polprasert; Isabell Schulze; Mikkael A. Sekeres; Hideki Makishima; Bartlomiej Przychodzen; Naoko Hosono; Jarnail Singh; Richard A. Padgett; Xiaorong Gu; James G. Phillips; Michael Clemente; Yvonne Parker; Daniel Lindner; Brittney Dienes; Eckhard Jankowsky; Yogen Saunthararajah; Yang Du; Kevin Oakley; Nhu Nguyen; Sudipto Mukherjee; Caroline Pabst; Lucy A. Godley; Jane E. Churpek; Daniel A. Pollyea; Utz Krug; Wolfgang E. Berdel; Hans-Ulrich Klein; Martin Dugas; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Kenichi Yoshida; Seishi Ogawa; Carsten Mueller-Tidow; Jaroslaw P. Maciejewski

  CANCER CELL, 2015年05月, 査読有り

  
• Identification of a homozygous JAK3 V674A mutation caused by acquired uniparental disomy in a relapsed early T-cell precursor ALL patient

  Sachiko Kawashima-Goto; Toshihiko Imamura; Masafumi Seki; Motohiro Kato; Kenichi Yoshida; Atsuya Sugimoto; Daisuke Kaneda; Atsushi Fujiki; Mitsuru Miyachi; Takuya Nakatani; Shinya Osone; Hiroyuki Ishida; Tomohiko Taki; Junko Takita; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Seishi Ogawa; Hajime Hosoi

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2015年04月, 査読有り

  
• A Female Patient with Incomplete Hemophagocytic Lymphohistiocytosis Caused by a Heterozygous XIAP Mutation Associated with Non-Random X-Chromosome Inactivation Skewed Towards the Wild-Type XIAP Allele

  Xi Yang; Akihiro Hoshino; Takashi Taga; Tomoaki Kunitsu; Yuhachi Ikeda; Takahiro Yasumi; Kenichi Yoshida; Taizo Wada; Kunio Miyake; Takeo Kubota; Yusuke Okuno; Hideki Muramatsu; Yuichi Adachi; Satoru Miyano; Seishi Ogawa; Seiji Kojima; Hirokazu Kanegane

  JOURNAL OF CLINICAL IMMUNOLOGY, 2015年04月, 査読有り

  
• Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia

  RuNan Wang; Kenichi Yoshida; Tsutomu Toki; Takafumi Sawada; Tamayo Uechi; Yusuke Okuno; Aiko Sato-Otsubo; Kazuko Kudo; Isamu Kamimaki; Rika Kanezaki; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Kiminori Terui; Tomohiko Sato; Yuji Iribe; Shouichi Ohga; Madoka Kuramitsu; Isao Hamaguchi; Akira Ohara; Junichi Hara; Kumiko Goi; Kousaku Matsubara; Kenichi Koike; Akira Ishiguro; Yasuhiro Okamoto; Kenichiro Watanabe; Hitoshi Kanno; Seiji Kojima; Satoru Miyano; Naoya Kenmochi; Seishi Ogawa; Etsuro Ito

  BRITISH JOURNAL OF HAEMATOLOGY, 2015年03月, 査読有り

  
• Establishment and Characterization of Novel Human Primary and Metastatic Anaplastic Thyroid Cancer Cell Lines and Their Genomic Evolution Over a Year as a Primagraft

  Manoj Garg; Ryoko Okamoto; Yasunobu Nagata; Deepika Kanojia; Subhashree Venkatesan; M. T. Anand; Glenn D. Braunstein; Jonathan W. Said; Ngan B. Doan; Quoc Ho; Tadayuki Akagi; Sigal Gery; Li-zhen Liu; Kar Tong Tan; Wee Joo Chng; Henry Yang; Seishi Ogawa; H. Phillip Koeffler

  JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2015年02月, 査読有り

  
• Aggressive transformation of anaplastic large cell lymphoma with increased number of ALK-translocated chromosomes

  Akihiro Hoshino; Keiko Nomura; Takeru Hamashima; Tomoya Isobe; Masafumi Seki; Mitsuteru Hiwatari; Kenichi Yoshida; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Seishi Ogawa; Junko Takita; Hirokazu Kanegane

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2015年02月, 査読有り

  
• Genomon ITDetector: a tool for somatic internal tandem duplication detection from cancer genome sequencing data

  Kenichi Chiba; Yuichi Shiraishi; Yasunobu Nagata; Kenichi Yoshida; Seiya Imoto; Seishi Ogawa; Satoru Miyano

  BIOINFORMATICS, 2015年01月, 査読有り

  
• Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia

  Bogdan Dumitriu; Xingmin Feng; Danielle M. Townsley; Yasutaka Ueda; Tetsuichi Yoshizato; Rodrigo T. Calado; Yanqin Yang; Yoshiyuki Wakabayashi; Sachiko Kajigaya; Seishi Ogawa; Jun Zhu; Neal S. Young

  BLOOD, 2015年01月, 査読有り

  
• Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance

  Daniel Nowak; Natalia L. M. Liem; Maximilian Mossner; Marion Klaumuenzer; Rachael A. Papa; Verena Nowak; Johann C. Jann; Tadayuki Akagi; Norihiko Kawamata; Ryoko Okamoto; Nils H. Thoennissen; Motohiro Kato; Masashi Sanada; Wolf-Karsten Hofmann; Seishi Ogawa; Glenn M. Marshall; Richard B. Lock; H. Phillip Koeffler

  EXPERIMENTAL HEMATOLOGY, 2015年01月, 査読有り

  
• Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome

  Vikas Madan; Deepika Kanojia; Jia Li; Ryoko Okamoto; Aiko Sato-Otsubo; Alexander Kohlmann; Masashi Sanada; Vera Grossmann; Janani Sundaresan; Yuichi Shiraishi; Satoru Miyano; Felicitas Thol; Arnold Ganser; Henry Yang; Torsten Haferlach; Seishi Ogawa; H. Phillip Koeffler

  NATURE COMMUNICATIONS, 2015年01月, 査読有り

  
• G17V RHOA: Genetic evidence of GTP-unbound RHOA playing a role in tumorigenesis in T cells

  Shigeru Chiba; Terukazu Enami; Seishi Ogawa; Mamiko Sakata-Yanagimoto

  Small GTPases, 2015年01月01日, 査読有り

  
• HapMuC: somatic mutation calling using heterozygous germ line variants near candidate mutations

  Naoto Usuyama; Yuichi Shiraishi; Yusuke Sato; Haruki Kume; Yukio Homma; Seishi Ogawa; Satoru Miyano; Seiya Imoto

  BIOINFORMATICS, 2014年12月, 査読有り

  
• Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis

  Gulzar Ahmad; Bhopal C. Mohapatra; Nancy A. Schulte; Scott A. Nadeau; Haitao Luan; Neha Zutshi; Eric Tom; Cesar Ortega-Cava; Chun Tu; Masashi Sanada; Seishi Ogawa; Myron L. Toews; Vimla Band; Hamid Band

  INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2014年12月, 査読有り

  
• A robust molecular pattern for myelodysplastic syndromes in two independent cohorts investigated by next-generation sequencing can be revealed by comparative bioinformatic analyses

  Dominic Rose; Alexander Kohlmann; Yasunobu Nagata; Seishi Ogawa; Claudia Haferlach; Wolfgang Kern; Susanne Schnittger; Torsten Haferlach

  BRITISH JOURNAL OF HAEMATOLOGY, 2014年10月, 査読有り

  
• Expressional changes of genes and miRNA in common megakaryocyte-erythroid progenitors from lower-risk myelodysplastic syndrome

  Kazuhiro Maki; Ko Sasaki; Yasunobu Nagata; Fusako Nagasawa; Yuka Nakamura; Seishi Ogawa; Kinuko Mitani

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2014年10月, 査読有り

  
• Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria

  Wenyi Shen; Michael J. Clemente; Naoko Hosono; Kenichi Yoshida; Bartlomiej Przychodzen; Tetsuichi Yoshizato; Yuichi Shiraishi; Satoru Miyano; Seishi Ogawa; Jaroslaw P. Maciejewski; Hideki Makishima

  JOURNAL OF CLINICAL INVESTIGATION, 2014年10月, 査読有り

  
• Detection of the G17V RHOA Mutation in Angioimmunoblastic T-Cell Lymphoma and Related Lymphomas Using Quantitative Allele-Specific PCR

  Rie Nakamoto-Matsubara; Mamiko Sakata-Yanagimoto; Terukazu Enami; Kenichi Yoshida; Shintaro Yanagimoto; Yusuke Shiozawa; Tohru Nanmoku; Kaishi Satomi; Hideharu Muto; Naoshi Obara; Takayasu Kato; Naoki Kurita; Yasuhisa Yokoyama; Koji Izutsu; Yasunori Ota; Masashi Sanada; Seiichi Shimizu; Takuya Komeno; Yuji Sato; Takayoshi Ito; Issay Kitabayashi; Kengo Takeuchi; Naoya Nakamura; Seishi Ogawa; Shigeru Chiba

  PLOS ONE, 2014年10月, 査読有り

  
• MDS-related mutations in aplastic anemia

  Seishi Ogawa

  BLOOD, 2014年10月, 査読有り

  
• Acquired Initiating Mutations in Early Hematopoietic Cells of CLL Patients

  Frederik Damm; Elena Mylonas; Adrien Cosson; Kenichi Yoshida; Veronique Della Valle; Enguerran Mouly; M'boyba Diop; Laurianne Scourzic; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Yoshikane Kikushige; Frederick Davi; Jerome Lambert; Daniel Gautheret; Helene Merle-Beral; Laurent Sutton; Philippe Dessen; Eric Solary; Koichi Akashi; William Vainchenker; Thomas Mercher; Nathalie Droin; Seishi Ogawa; Florence Nguyen-Khac; Olivier A. Bernard

  CANCER DISCOVERY, 2014年09月, 査読有り

  
• Generation of Alveolar Epithelial Spheroids via Isolated Progenitor Cells from Human Pluripotent Stem Cells

  Shimpei Gotoh; Isao Ito; Tadao Nagasaki; Yuki Yamamoto; Satoshi Konishi; Yohei Korogi; Hisako Matsumoto; Shigeo Muro; Toyohiro Hirai; Michinori Funato; Shin-Ichi Mae; Taro Toyoda; Aiko Sato-Otsubo; Seishi Ogawa; Kenji Osafune; Michiaki Mishima

  STEM CELL REPORTS, 2014年09月, 査読有り

  この論文にアクセスする：

  
• The genomic landscape of nasopharyngeal carcinoma

  De-Chen Lin; Xuan Meng; Masaharu Hazawa; Yasunobu Nagata; Ana Maria Varela; Liang Xu; Yusuke Sato; Li-Zhen Liu; Ling-Wen Ding; Arjun Sharma; Boon Cher Goh; Soo Chin Lee; Bengt Fredrik Petersson; Feng Gang Yu; Paul Macary; Min Zin Oo; Chan Soh Ha; Henry Yang; Seishi Ogawa; Kwok Seng Loh; H. Phillip Koeffler

  NATURE GENETICS, 2014年08月, 査読有り

  
• Splicing factor mutations and cancer

  Kenichi Yoshida; Seishi Ogawa

  WILEY INTERDISCIPLINARY REVIEWS-RNA, 2014年07月, 査読有り

  この論文にアクセスする：

  
• [Molecular profiling of myelodysplastic syndromes].

  Ogawa S

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014年07月, 査読有り

  
• Recurrent genetic defects on chromosome 7q in myeloid neoplasms

  N. Hosono; H. Makishima; A. Jerez; K. Yoshida; B. Przychodzen; S. McMahon; Y. Shiraishi; K. Chiba; H. Tanaka; S. Miyano; M. Sanada; I. Gomez-Segui; A. K. Verma; M. A. McDevitt; M. A. Sekeres; S. Ogawa; J. P. Maciejewski

  LEUKEMIA, 2014年06月, 査読有り

  
• High-resolution genomic copy number profiling of primary intraocular lymphoma by single nucleotide polymorphism microarrays

  Ludan Wang; Aiko Sato-Otsubo; Sunao Sugita; Hiroshi Takase; Manabu Mochizuki; Yoshihiko Usui; Hiroshi Goto; Takatoshi Koyama; Hiroki Akiyama; Osamu Miura; Seishi Ogawa; Ayako Arai

  CANCER SCIENCE, 2014年05月, 査読有り

  
• KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells

  Takeo Nakaya; Seishi Ogawa; Ichiro Manabe; Masami Tanaka; Masashi Sanada; Toshiro Sato; Makoto M. Taketo; Kazuki Nakao; Hans Clevers; Masashi Fukayama; Masahiko Kuroda; Ryozo Nagai

  CANCER RESEARCH, 2014年05月, 査読有り

  
• Biallelic DICER1 Mutations in Sporadic Pleuropulmonary Blastoma

  Masafumi Seki; Kenichi Yoshida; Yuichi Shiraishi; Teppei Shimamura; Yusuke Sato; Riki Nishimura; Yusuke Okuno; Kenichi Chiba; Hiroko Tanaka; Keisuke Kato; Motohiro Kato; Ryoji Hanada; Yuko Nomura; Myoung-Ja Park; Toshiaki Ishida; Akira Oka; Takashi Igarashi; Satoru Miyano; Yasuhide Hayashi; Seishi Ogawa; Junko Takita

  CANCER RESEARCH, 2014年05月, 査読有り

  
• Genomic and molecular characterization of esophageal squamous cell carcinoma

  De-Chen Lin; Jia-Jie Hao; Yasunobu Nagata; Liang Xu; Li Shang; Xuan Meng; Yusuke Sato; Yusuke Okuno; Ana Maria Varela; Ling-Wen Ding; Manoj Garg; Li-Zhen Liu; Henry Yang; Dong Yin; Zhi-Zhou Shi; Yan-Yi Jiang; Wen-Yue Gu; Ting Gong; Yu Zhang; Xin Xu; Ori Kalid; Sharon Shacham; Seishi Ogawa; Ming-Rong Wang; H. Phillip Koeffler

  NATURE GENETICS, 2014年05月, 査読有り

  
• Splicing factor mutations in AML

  Seishi Ogawa

  BLOOD, 2014年05月, 査読有り

  
• Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome

  Yusuke Sato; Shigekatsu Maekawa; Ryohei Ishii; Masashi Sanada; Teppei Morikawa; Yuichi Shiraishi; Kenichi Yoshida; Yasunobu Nagata; Aiko Sato-Otsubo; Tetsuichi Yoshizato; Hiromichi Suzuki; Yusuke Shiozawa; Keisuke Kataoka; Ayana Kon; Kosuke Aoki; Kenichi Chiba; Hiroko Tanaka; Haruki Kume; Satoru Miyano; Masashi Fukayama; Osamu Nureki; Yukio Homma; Seishi Ogawa

  SCIENCE, 2014年05月, 査読有り

  
• Whole-exome sequence analysis of ataxia telangiectasia-like phenotype

  Setsuko Hasegawa; Kohsuke Imai; Kenichi Yoshida; Yusuke Okuno; Hideki Muramatsu; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Seiji Kojima; Seishi Ogawa; Tomohiro Morio; Shuki Mizutani; Masatoshi Takagi

  JOURNAL OF THE NEUROLOGICAL SCIENCES, 2014年05月, 査読有り

  
• Tracing the development of acute myeloid leukemia in CBL syndrome

  Heiko Becker; Kenichi Yoshida; Nadja Blagitko-Dorfs; Rainer Claus; Milena Pantic; Mahmoud Abdelkarim; Christoph Niemoeller; Christine Greil; Bjoern Hackanson; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Konstanze Doehner; Susanne Schnittger; Philipp Henneke; Charlotte M. Niemeyer; Christian Flotho; Dietmar Pfeifer; Seishi Ogawa; Michael Luebbert

  BLOOD, 2014年03月, 査読有り

  
• DNA Methyltransferase Inhibition Reverses Epigenetically Embedded Phenotypes in Lung Cancer Preferentially Affecting Polycomb Target Genes

  Antje Hascher; Ann-Kristin Haase; Katja Hebestreit; Christian Rohde; Hans-Ulrich Klein; Maria Rius; Dominik Jungen; Anika Witten; Monika Stoll; Isabell Schulze; Seishi Ogawa; Rainer Wiewrodt; Lara Tickenbrock; Wolfgang E. Berdel; Martin Dugas; Nils H. Thoennissen; Carsten Mueller-Tidow

  CLINICAL CANCER RESEARCH, 2014年02月, 査読有り

  
• Somatic RHOA mutation in angioimmunoblastic T cell lymphoma

  Mamiko Sakata-Yanagimoto; Terukazu Enami; Kenichi Yoshida; Yuichi Shiraishi; Ryohei Ishii; Yasuyuki Miyake; Hideharu Muto; Naoko Tsuyama; Aiko Sato-Otsubo; Yusuke Okuno; Seiji Sakata; Yuhei Kamada; Rie Nakamoto-Matsubara; Nguyen Bich Tran; Koji Izutsu; Yusuke Sato; Yasunori Ohta; Junichi Furuta; Seiichi Shimizu; Takuya Komeno; Yuji Sato; Takayoshi Ito; Masayuki Noguchi; Emiko Noguchi; Masashi Sanada; Kenichi Chiba; Hiroko Tanaka; Kazumi Suzukawa; Toru Nanmoku; Yuichi Hasegawa; Osamu Nureki; Satoru Miyano; Naoya Nakamura; Kengo Takeuchi; Seishi Ogawa; Shigeru Chiba

  NATURE GENETICS, 2014年02月, 査読有り

  
• Genome-wide approach to identify second gene targets for malignant rhabdoid tumors using high-density oligonucleotide microarrays

  Junko Takita; Yuyan Chen; Motohiro Kato; Kentaro Ohki; Yusuke Sato; Shigeru Ohta; Kanji Sugita; Riki Nishimura; Noriko Hoshino; Masafumi Seki; Masashi Sanada; Akira Oka; Yasuhide Hayashi; Seishi Ogawa

  Cancer Science, 2014年, 査読有り

  
• Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations

  Tung-Liang Lin; Yasunobu Nagata; Hsiao-Wen Kao; Masashi Sanada; Yusuke Okuno; Chein-Fuang Huang; Der-Cherng Liang; Ming-Chung Kuo; Chang-Liang Lai; En-Hui Lee; Yu-Shu Shih; Hiroko Tanaka; Yuichi Shiraishi; Kenichi Chiba; Tung-Huei Lin; Jin-Hou Wu; Satoru Miyano; Seishi Ogawa; Lee-Yung Shih

  HAEMATOLOGICA, 2014年01月, 査読有り

  
• Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders

  Tomoya Muto; Goro Sashida; Motohiko Oshima; George R. Wendt; Makiko Mochizuki-Kashio; Yasunobu Nagata; Masashi Sanada; Satoru Miyagi; Atsunori Saraya; Asuka Kamio; Genta Nagae; Chiaki Nakaseko; Koutaro Yokote; Kazuya Shimoda; Haruhiko Koseki; Yutaka Suzuki; Sumio Sugano; Hiroyuki Aburatani; Seishi Ogawa; Atsushi Iwama

  JOURNAL OF EXPERIMENTAL MEDICINE, 2013年11月, 査読有り

  
• Normal neutrophil myosin IIA localization in an immunofluorescence analysis can rule out MYH9 disorders

  K. Kitamura; K. Yoshida; Y. Shiraishi; K. Chiba; H. Tanaka; K. Furukawa; S. Miyano; S. Ogawa; S. Kunishima

  JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2013年11月, 査読有り

  
• The landscape of somatic mutations in Down syndrome-related myeloid disorders

  Kenichi Yoshida; Tsutomu Toki; Yusuke Okuno; Rika Kanezaki; Yuichi Shiraishi; Aiko Sato-Otsubo; Masashi Sanada; Myoung-ja Park; Kiminori Terui; Hiromichi Suzuki; Ayana Kon; Yasunobu Nagata; Yusuke Sato; RuNan Wang; Norio Shiba; Kenichi Chiba; Hiroko Tanaka; Asahito Hama; Hideki Muramatsu; Daisuke Hasegawa; Kazuhiro Nakamura; Hirokazu Kanegane; Keiko Tsukamoto; Souichi Adachi; Kiyoshi Kawakami; Koji Kato; Ryosei Nishimura; Shai Izraeli; Yasuhide Hayashi; Satoru Miyano; Seiji Kojima; Etsuro Ito; Seishi Ogawa

  NATURE GENETICS, 2013年11月, 査読有り

  
• Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients.

  Asuka Hira; Hiromasa Yabe; Kenichi Yoshida; Yusuke Okuno; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Jun Nakamura; Seiji Kojima; Seishi Ogawa; Keitaro Matsuo; Minoru Takata; Miharu Yabe

  Blood, 2013年10月31日, 査読有り

  この論文にアクセスする：

  
• BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders

  Frederik Damm; Virginie Chesnais; Yasunobu Nagata; Kenichi Yoshida; Laurianne Scourzic; Yusuke Okuno; Raphael Itzykson; Masashi Sanada; Yuichi Shiraishi; Veronique Gelsi-Boyer; Aline Renneville; Satoru Miyano; Hiraku Mori; Lee-Yung Shih; Sophie Park; Francois Dreyfus; Agnes Guerci-Bresler; Eric Solary; Christian Rose; Stephane Cheze; Thomas Prebet; Norbert Vey; Marion Legentil; Yannis Duffourd; Stephane de Botton; Claude Preudhomme; Daniel Birnbaum; Olivier A. Bernard; Seishi Ogawa; Michaela Fontenay; Olivier Kosmider

  BLOOD, 2013年10月, 査読有り

  
• Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.

  Ayana Kon; Lee-Yung Shih; Masashi Minamino; Masashi Sanada; Yuichi Shiraishi; Yasunobu Nagata; Kenichi Yoshida; Yusuke Okuno; Masashige Bando; Ryuichiro Nakato; Shumpei Ishikawa; Aiko Sato-Otsubo; Genta Nagae; Aiko Nishimoto; Claudia Haferlach; Daniel Nowak; Yusuke Sato; Tamara Alpermann; Masao Nagasaki; Teppei Shimamura; Hiroko Tanaka; Kenichi Chiba; Ryo Yamamoto; Tomoyuki Yamaguchi; Makoto Otsu; Naoshi Obara; Mamiko Sakata-Yanagimoto; Tsuyoshi Nakamaki; Ken Ishiyama; Florian Nolte; Wolf-Karsten Hofmann; Shuichi Miyawaki; Shigeru Chiba; Hiraku Mori; Hiromitsu Nakauchi; H Phillip Koeffler; Hiroyuki Aburatani; Torsten Haferlach; Katsuhiko Shirahige; Satoru Miyano; Seishi Ogawa

  Nature genetics, 2013年10月, 査読有り

  
• Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies

  I. Gomez-Segui; H. Makishima; A. Jerez; K. Yoshida; B. Przychodzen; S. Miyano; Y. Shiraishi; H. D. Husseinzadeh; K. Guinta; M. Clemente; N. Hosono; M. A. McDevitt; A. R. Moliterno; M. A. Sekeres; S. Ogawa; J. P. Maciejewski

  LEUKEMIA, 2013年09月, 査読有り

  
• Two Susceptibility Loci to Takayasu Arteritis Reveal a Synergistic Role of the IL12B and HLA-B Regions in a Japanese Population

  Chikashi Terao; Hajime Yoshifuji; Akinori Kimura; Takayoshi Matsumura; Koichiro Ohmura; Meiko Takahashi; Masakazu Shimizu; Takahisa Kawaguchi; Zhiyong Chen; Taeko K. Naruse; Aiko Sato-Otsubo; Yusuke Ebana; Yasuhiro Maejima; Hideyuki Kinoshita; Kosaku Murakami; Daisuke Kawabata; Yoko Wada; Ichiei Narita; Junichi Tazaki; Yasushi Kawaguchi; Hisashi Yamanaka; Kimiko Yurugi; Yasuo Miura; Taira Maekawa; Seishi Ogawa; Issei Komuro; Ryozo Nagai; Ryo Yamada; Yasuharu Tabara; Mitsuaki Isobe; Tsuneyo Mimori; Fumihiko Matsuda

  AMERICAN JOURNAL OF HUMAN GENETICS, 2013年08月, 査読有り

  
• Bernard-Soulier syndrome caused by a hemizygous GPIbβ mutation and 22q11.2 deletion

  S. Kunishima; T. Imai; R. Kobayashi; M. Kato; S. Ogawa; H. Saito

  Pediatrics International, 2013年08月, 査読有り

  
• Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth

  Satomi Asanuma; Makoto Yamagishi; Katsuaki Kawanami; Kazumi Nakano; Aiko Sato-Otsubo; Satsuki Muto; Masashi Sanada; Tadanori Yamochi; Seiichiro Kobayashi; Atae Utsunomiya; Masako Iwanaga; Kazunari Yamaguchi; Kaoru Uchimaru; Seishi Ogawa; Toshiki Watanabe

  CANCER SCIENCE, 2013年08月, 査読有り

  
• Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia

  Hirotoshi Sakaguchi; Yusuke Okuno; Hideki Muramatsu; Kenichi Yoshida; Yuichi Shiraishi; Mariko Takahashi; Ayana Kon; Masashi Sanada; Kenichi Chiba; Hiroko Tanaka; Hideki Makishima; Xinan Wang; Yinyan Xu; Sayoko Doisaki; Asahito Hama; Koji Nakanishi; Yoshiyuki Takahashi; Nao Yoshida; Jaroslaw P. Maciejewski; Satoru Miyano; Seishi Ogawa; Seiji Kojima

  NATURE GENETICS, 2013年08月, 査読有り

  
• Somatic SETBP1 mutations in myeloid malignancies

  Hideki Makishima; Kenichi Yoshida; Nhu Nguyen; Bartlomiej Przychodzen; Masashi Sanada; Yusuke Okuno; Kwok Peng Ng; Kristbjorn O. Gudmundsson; Bandana A. Vishwakarma; Andres Jerez; Ines Gomez-Segui; Mariko Takahashi; Yuichi Shiraishi; Yasunobu Nagata; Kathryn Guinta; Hiraku Mori; Mikkael A. Sekeres; Kenichi Chiba; Hiroko Tanaka; Hideki Muramatsu; Hirotoshi Sakaguchi; Ronald L. Paquette; Michael A. McDevitt; Seiji Kojima; Yogen Saunthararajah; Satoru Miyano; Lee-Yung Shih; Yang Du; Seishi Ogawa; Jaroslaw P. Maciejewski

  NATURE GENETICS, 2013年08月, 査読有り

  
• Integrated molecular analysis of clear-cell renal cell carcinoma

  Yusuke Sato; Tetsuichi Yoshizato; Yuichi Shiraishi; Shigekatsu Maekawa; Yusuke Okuno; Takumi Kamura; Teppei Shimamura; Aiko Sato-Otsubo; Genta Nagae; Hiromichi Suzuki; Yasunobu Nagata; Kenichi Yoshida; Ayana Kon; Yutaka Suzuki; Kenichi Chiba; Hiroko Tanaka; Atsushi Niida; Akihiro Fujimoto; Tatsuhiko Tsunoda; Teppei Morikawa; Daichi Maeda; Haruki Kume; Sumio Sugano; Masashi Fukayama; Hiroyuki Aburatani; Masashi Sanada; Satoru Miyano; Yukio Homma; Seishi Ogawa

  NATURE GENETICS, 2013年08月, 査読有り

  
• Genetic differences between Asian and Caucasian chronic lymphocytic leukemia

  Norihiko Kawamata; Chimene Moreilhon; Takayuki Saitoh; Masamitsu Karasawa; Brian K. Bernstein; Aiko Sato-Otsubo; Seishi Ogawa; Sophie Raynaud; H. Phillip Koeffler

  INTERNATIONAL JOURNAL OF ONCOLOGY, 2013年08月, 査読有り

  
• Characterization of genetic lesions in rhabdomyosarcoma using a high-density single nucleotide polymorphism array

  Riki Nishimura; Junko Takita; Aiko Sato-Otsubo; Motohiro Kato; Katsuyoshi Koh; Ryoji Hanada; Yukichi Tanaka; Keisuke Kato; Daichi Maeda; Masashi Fukayama; Masashi Sanada; Yasuhide Hayashi; Seishi Ogawa

  CANCER SCIENCE, 2013年07月, 査読有り

  
• Aggressive Transformation of Juvenile Myelomonocytic Leukemia Associated with Duplication of Oncogenic KRAS due to Acquired Uniparental Disomy

  Motohiro Kato; Naoko Yasui; Masafumi Seki; Hiroshi Kishimoto; Aiko Sato-Otsubo; Daisuke Hasegawa; Nobutaka Kiyokawa; Ryoji Hanada; Seishi Ogawa; Atsushi Manabe; Junko Takita; Katsuyoshi Koh

  JOURNAL OF PEDIATRICS, 2013年06月, 査読有り

  
• Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome

  Satoshi Saida; Ken-ichiro Watanabe; Aiko Sato-Otsubo; Kiminori Terui; Kenichi Yoshida; Yusuke Okuno; Tsutomu Toki; RuNan Wang; Yuichi Shiraishi; Satoru Miyano; Itaru Kato; Tatsuya Morishima; Hisanori Fujino; Katsutsugu Umeda; Hidefumi Hiramatsu; Souichi Adachi; Etsuro Ito; Seishi Ogawa; Mamoru Ito; Tatsutoshi Nakahata; Toshio Heike

  BLOOD, 2013年05月, 査読有り

  
• Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival

  D. H. Lee; S. Amanat; C. Goff; L. M. Weiss; J. W. Said; N. B. Doan; A. Sato-Otsubo; S. Ogawa; C. Forscher; H. P. Koeffler

  ONCOGENESIS, 2013年05月, 査読有り

  
• An empirical Bayesian framework for somatic mutation detection from cancer genome sequencing data

  Yuichi Shiraishi; Yusuke Sato; Kenichi Chiba; Yusuke Okuno; Yasunobu Nagata; Kenichi Yoshida; Norio Shiba; Yasuhide Hayashi; Haruki Kume; Yukio Homma; Masashi Sanada; Seishi Ogawa; Satoru Miyano

  NUCLEIC ACIDS RESEARCH, 2013年04月, 査読有り

  
• ACTN1 Mutations Cause Congenital Macrothrombocytopenia

  Shinji Kunishima; Yusuke Okuno; Kenichi Yoshida; Yuichi Shiraishi; Masashi Sanada; Hideki Muramatsu; Kenichi Chiba; Hiroko Tanaka; Koji Miyazaki; Michio Sakai; Masatoshi Ohtake; Ryoji Kobayashi; Akihiro Iguchi; Gen Niimi; Makoto Otsu; Yoshiyuki Takahashi; Satoru Miyano; Hidehiko Saito; Seiji Kojima; Seishi Ogawa

  AMERICAN JOURNAL OF HUMAN GENETICS, 2013年03月, 査読有り

  
• Smap1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia

  Shunsuke Kon; Naoko Minegishi; Kenji Tanabe; Toshio Watanabe; Tomo Funaki; Won Fen Wong; Daisuke Sakamoto; Yudai Higuchi; Hiroshi Kiyonari; Katsutoshi Asano; Yoichiro Iwakura; Manabu Fukumoto; Motomi Osato; Masashi Sanada; Seishi Ogawa; Takuro Nakamura; Masanobu Satake

  JOURNAL OF CLINICAL INVESTIGATION, 2013年03月, 査読有り

  
• miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiforme

  D. Yin; S. Ogawa; N. Kawamata; A. Leiter; M. Ham; D. Li; N. B. Doans; J. W. Said; K. L. Black; H. Phillip Koeffler

  ONCOGENE, 2013年02月, 査読有り

  
• Deep sequencing in cancer research

  Kenichi Yoshida; Masashi Sanada; Seishi Ogawa

  Japanese Journal of Clinical Oncology, 2013年02月, 査読有り

  
• Alterations of the genes involved in the PI3K and estrogen-receptor pathways influence outcome in human epidermal growth factor receptor 2-positive and hormone receptor-positive breast cancer patients treated with trastuzumab-containing neoadjuvant chemot

  M. Takada; T. Higuchi; K. Tozuka; H. Takei; M. Haruta; J. Watanabe; F. Kasai; K. Inoue; M. Kurosumi; M. Miyazaki; A. Sato-Otsubo; S. Ogawa; Y. Kaneko

  BMC cancer, 2013年, 査読有り

  
• Erratum: The landscape of somatic mutations in Down syndrome-related myeloid disorders (Nature Genetics (2013) 45 (1293-1299))

  K. Yoshida; T. Toki; Y. Okuno; R. Kanezaki; Y. Shiraishi; A. Sato-Otsubo; M. Sanada; M.-J. Park; K. Terui; H. Suzuki; A. Kon; Y. Nagata; Y. Sato; R. Wang; N. Shiba; K. Chiba; H. Tanaka; A. Hama; H. Muramatsu; D. Hasegawa; K. Nakamura; H. Kanegane; K. Tsukamoto; S. Adachi; K. Kawakami; K. Kato; R. Nishimura; S. Izraeli; Y. Hayashi; S. Miyano; S. Kojima; E. Ito; S. Ogawa

  Nature Genetics, 2013年, 査読有り

  
• Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer

  R. Iwakawa; M. Takenaka; T. Kohno; Y. Shimada; Y. Totoki; T. Shibata; K. Tsuta; R. Nishikawa; M. Noguchi; A. Sato-Otsubo; S. Ogawa; J. Yokota

  Genes Chromosomes and Cancer, 2013年, 査読有り

  
• Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

  Shin-Ichi Mae; Akemi Shono; Fumihiko Shiota; Tetsuhiko Yasuno; Masatoshi Kajiwara; Nanaka Gotoda-Nishimura; Sayaka Arai; Aiko Sato-Otubo; Taro Toyoda; Kazutoshi Takahashi; Naoki Nakayama; Chad A. Cowan; Takashi Aoi; Seishi Ogawa; Andrew P. McMahon; Shinya Yamanaka; Kenji Osafune

  Nature Communications, 2013年, 査読有り

  
• Clinical and genetic characteristics of congenital sideroblastic anemia: comparison with myelodysplastic syndrome with ring sideroblast (MDS-RS)

  Rie Ohba; Kazumichi Furuyama; Kenichi Yoshida; Tohru Fujiwara; Noriko Fukuhara; Yasushi Onishi; Atsushi Manabe; Etsuro Ito; Keiya Ozawa; Seiji Kojima; Seishi Ogawa; Hideo Harigae

  ANNALS OF HEMATOLOGY, 2013年01月, 査読有り

  
• Allelotypes of lung adenocarcinomas featuring ALK fusion demonstrate fewer onco- and suppressor gene changes

  Hironori Ninomiya; Motohiro Kato; Masashi Sanada; Kengo Takeuchi; Kentaro Inamura; Noriko Motoi; Hiroko Nagano; Kimie Nomura; Yukinori Sakao; Sakae Okumura; Hiroyuki Mano; Seishi Ogawa; Yuichi Ishikawa

  BMC CANCER, 2013年01月, 査読有り

  
• EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms

  T. Ueda; M. Sanada; H. Matsui; N. Yamasaki; Z-I Honda; L-Y Shih; H. Mori; T. Inaba; S. Ogawa; H. Honda

  LEUKEMIA, 2012年12月, 査読有り

  
• Favorable outcome of patients who have 13q deletion: a suggestion for revision of the WHO 'MDS-U' designation

  Kohei Hosokawa; Takamasa Katagiri; Naomi Sugimori; Ken Ishiyama; Yumi Sasaki; Yu Seiki; Aiko Sato-Otsubo; Masashi Sanada; Seishi Ogawa; Shinji Nakao

  HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2012年12月, 査読有り

  
• Aberrant activation of ALK kinase by a novel truncated form ALK protein in neuroblastoma

  J. Okubo; J. Takita; Y. Chen; K. Oki; R. Nishimura; M. Kato; M. Sanada; M. Hiwatari; Y. Hayashi; T. Igarashi; S. Ogawa

  ONCOGENE, 2012年11月, 査読有り

  
• Splicing factor mutations in myelodysplasia

  Seishi Ogawa

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2012年10月, 査読有り

  
• Identification of unbalanced genome copy number abnormalities in patients with multiple myeloma by single-nucleotide polymorphism genotyping microarray analysis

  Yuhei Kamada; Mamiko Sakata-Yanagimoto; Masashi Sanada; Aiko Sato-Otsubo; Terukazu Enami; Kazumi Suzukawa; Naoki Kurita; Hidekazu Nishikii; Yasuhisa Yokoyama; Yasushi Okoshi; Yuichi Hasegawa; Seishi Ogawa; Shigeru Chiba

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2012年10月, 査読有り

  
• SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

  Manja Meggendorfer; Andreas Roller; Torsten Haferlach; Christiane Eder; Frank Dicker; Vera Grossmann; Alexander Kohlmann; Tamara Alpermann; Kenichi Yoshida; Seishi Ogawa; H. Phillip Koeffler; Wolfgang Kern; Claudia Haferlach; Susanne Schnittger

  BLOOD, 2012年10月, 査読有り

  
• Deletion of the TNFAIP3/A20 gene detected by FICTION analysis in classical Hodgkin lymphoma

  Junko Nomoto; Nobuhiro Hiramoto; Motohiro Kato; Masashi Sanada; Akiko Miyagi Maeshima; Hirokazu Taniguchi; Fumie Hosoda; Yoshitaka Asakura; Wataru Munakata; Naohiro Sekiguchi; Dai Maruyama; Takashi Watanabe; Hitoshi Nakagama; Kengo Takeuchi; Kensei Tobinai; Seishi Ogawa; Yukio Kobayashi

  BMC CANCER, 2012年10月, 査読有り

  
• Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery

  Takayuki Tanaka; Kazutoshi Takahashi; Mayu Yamane; Shota Tomida; Saori Nakamura; Koichi Oshima; Akira Niwa; Ryuta Nishikomori; Naotomo Kambe; Hideki Hara; Masao Mitsuyama; Nobuhiro Morone; John E. Heuser; Takuya Yamamoto; Akira Watanabe; Aiko Sato-Otsubo; Seishi Ogawa; Isao Asaka; Toshio Heike; Shinya Yamanaka; Tatsutoshi Nakahata; Megumu K. Saito

  BLOOD, 2012年08月, 査読有り

  
• Novel splicing-factor mutations in juvenile myelomonocytic leukemia

  J. Takita; K. Yoshida; M. Sanada; R. Nishimura; J. Okubo; A. Motomura; M. Hiwatari; K. Oki; T. Igarashi; Y. Hayashi; S. Ogawa

  LEUKEMIA, 2012年08月, 査読有り

  
• HapMap SNP Scanner: An online program to mine SNPs responsible for cell phenotype

  T. Yamamura; J. Hikita; M. Bleakley; T. Hirosawa; A. Sato-Otsubo; H. Torikai; T. Hamajima; Y. Nannya; A. Demachi-Okamura; E. Maruya; H. Saji; Y. Yamamoto; T. Takahashi; N. Emi; Y. Morishima; Y. Kodera; K. Kuzushima; S. R. Riddell; S. Ogawa; Y. Akatsuka

  Tissue Antigens, 2012年08月, 査読有り

  
• SNP array analysis of acute promyelocytic leukemia may be of prognostic relevance and identifies a potential high risk group with recurrent deletions on chromosomal subband 1q31.3

  Daniel Nowak; Marion Klaumuenzer; Benjamin Hanfstein; Maximilian Mossner; Florian Nolte; Verena Nowak; Julia Oblaender; Anna Hecht; Gero Huetter; Seishi Ogawa; Alexander Kohlmann; Claudia Haferlach; Brigitte Schlegelberger; Jan Braess; Wolfgang Seifarth; Alice Fabarius; Philipp Erben; Susanne Saussele; Martin C. Mueller; Andreas Reiter; Thomas Buechner; Christel Weiss; Wolf-Karsten Hofmann; Eva Lengfelder

  GENES CHROMOSOMES & CANCER, 2012年08月, 査読有り

  
• Genome-wide Analysis of Myelodysplastic Syndromes

  Masashi Sanada; Seishi Ogawa

  CURRENT PHARMACEUTICAL DESIGN, 2012年07月, 査読有り

  
• Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma

  Reika Iwakawa; Hirokazu Okayama; Takashi Kohno; Aiko Sato-Otsubo; Seishi Ogawa; Jun Yokota

  GENES CHROMOSOMES & CANCER, 2012年05月, 査読有り

  
• Older patients with normal karyotype acute myeloid leukemia have a higher rate of genomic changes compared to young patients as determined by SNP array analysis

  Maya Koren-Michowitz; Aiko Sato-Otsubo; Arnon Nagler; Torsten Haferlach; Seishi Ogawa; H. Phillip Koeffler

  LEUKEMIA RESEARCH, 2012年04月, 査読有り

  
• Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia

  Madoka Kuramitsu; Aiko Sato-Otsubo; Tomohiro Morio; Masatoshi Takagi; Tsutomu Toki; Kiminori Terui; RuNan Wang; Hitoshi Kanno; Shouichi Ohga; Akira Ohara; Seiji Kojima; Toshiyuki Kitoh; Kumiko Goi; Kazuko Kudo; Tadashi Matsubayashi; Nobuo Mizue; Michio Ozeki; Atsuko Masumi; Haruka Momose; Kazuya Takizawa; Takuo Mizukami; Kazunari Yamaguchi; Seishi Ogawa; Etsuro Ito; Isao Hamaguchi

  BLOOD, 2012年03月, 査読有り

  
• CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia (FPD/AML)

  Norio Shiba; Daisuke Hasegawa; Myoung-ja Park; Chisato Murata; Aiko Sato-Otsubo; Chitose Ogawa; Atsushi Manabe; Hirokazu Arakawa; Seishi Ogawa; Yasuhide Hayashi

  BLOOD, 2012年03月, 査読有り

  
• Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML

  Shinsuke Hirabayashi; Christian Flotho; Jessica Moetter; Michael Heuser; Henrik Hasle; Bernd Gruhn; Thomas Klingebiel; Felicitas Thol; Brigitte Schlegelberger; Irith Baumann; Brigitte Strahm; Jan Stary; Franco Locatelli; Marco Zecca; Eva Bergstraesser; Michael Dworzak; Marry M. van den Heuvel-Eibrink; Barbara De Moerloose; Seishi Ogawa; Charlotte M. Niemeyer; Marcin W. Wlodarski

  BLOOD, 2012年03月, 査読有り

  
• KIF5B-RET fusions in lung adenocarcinoma

  Takashi Kohno; Hitoshi Ichikawa; Yasushi Totoki; Kazuki Yasuda; Masaki Hiramoto; Takao Nammo; Hiromi Sakamoto; Koji Tsuta; Koh Furuta; Yoko Shimada; Reika Iwakawa; Hideaki Ogiwara; Takahiro Oike; Masato Enari; Aaron J. Schetter; Hirokazu Okayama; Aage Haugen; Vidar Skaug; Suenori Chiku; Itaru Yamanaka; Yasuhito Arai; Shun-ichi Watanabe; Ikuo Sekine; Seishi Ogawa; Curtis C. Harris; Hitoshi Tsuda; Teruhiko Yoshida; Jun Yokota; Tatsuhiro Shibata

  NATURE MEDICINE, 2012年03月, 査読有り

  
• CBL mutations in infant acute lymphoblastic leukaemia

  Norio Shiba; Myoung-Ja Park; Tomohiko Taki; Junko Takita; Mitsuteru Hiwatari; Takashi Kanazawa; Manabu Sotomatsu; Eiichi Ishii; Hirokazu Arakawa; Seishi Ogawa; Yasuhide Hayashi

  BRITISH JOURNAL OF HAEMATOLOGY, 2012年03月, 査読有り

  
• Single-Nucleotide Polymorphism Array Karyotyping in Clinical Practice: Where, When, and How?

  Aiko Sato-Otsubo; Masashi Sanada; Seishi Ogawa

  SEMINARS IN ONCOLOGY, 2012年02月, 査読有り

  
• [Genome-wide analysis of AML and MDS].

  S. Ogawa

  Nihon rinsho. Japanese journal of clinical medicine, 2012年, 査読有り

  
• [Bone marrow failure syndrome (idiopathic hematopoietic disorders): progress in diagnosis and treatment. Topics: IV. Recent topics of hematopoiesis; 1. Novel molecular mechanism of myelodysplastic syndromes].

  K. Yoshida; M. Sanada; S. Ogawa

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2012年, 査読有り

  
• Polycomb-mediated loss of miR-31 activates nik-dependent NF-κB pathway in adult T cell leukemia and other cancers

  M. Yamagishi; K. Nakano; A. Miyake; T. Yamochi; Y. Kagami; A. Tsutsumi; Y. Matsuda; A. Sato-Otsubo; S. Muto; A. Utsunomiya; K. Yamaguchi; K. Uchimaru; S. Ogawa; T. Watanabe

  Cancer Cell, 2012年01月, 査読有り

  
• Frequent loss of HLA alleles associated with copy number-neutral 6pLOH in acquired aplastic anemia

  Takamasa Katagiri; Aiko Sato-Otsubo; Koichi Kashiwase; Satoko Morishima; Yusuke Sato; Yuka Mori; Motohiro Kato; Masashi Sanada; Yasuo Morishima; Kohei Hosokawa; Yumi Sasaki; Shigeki Ohtake; Seishi Ogawa; Shinji Nakao

  BLOOD, 2011年12月, 査読有り

  
• Crk-associated substrate lymphocyte type regulates myeloid cell motility and suppresses the progression of leukemia induced by p210Bcr/Abl

  Sachiko Seo; Tetsuya Nakamoto; Masataka Takeshita; Jun Lu; Tomohiko Sato; Takahiro Suzuki; Yasuhiko Kamikubo; Motoshi Ichikawa; Motoshi Noda; Seishi Ogawa; Hiroaki Honda; Hideaki Oda; Mineo Kurokawa

  CANCER SCIENCE, 2011年12月, 査読有り

  
• A High Occurrence of Acquisition and/or Expansion of C-CBL Mutant Clones in the Progression of High-Risk Myelodysplastic Syndrome to Acute Myeloid Leukemia

  Hsiao-Wen Kao; Masashi Sanada; Der-Cherng Liang; Chang-Liang Lai; En-Hui Lee; Ming-Chung Kuo; Tung-Liang Lin; Yu-Shu Shih; Jin-Hou Wu; Chein-Fuang Huang; Seishi Ogawa; Lee-Yung Shih

  NEOPLASIA, 2011年11月, 査読有り

  
• Frequent pathway mutations of splicing machinery in myelodysplasia

  Kenichi Yoshida; Masashi Sanada; Yuichi Shiraishi; Daniel Nowak; Yasunobu Nagata; Ryo Yamamoto; Yusuke Sato; Aiko Sato-Otsubo; Ayana Kon; Masao Nagasaki; George Chalkidis; Yutaka Suzuki; Masashi Shiosaka; Ryoichiro Kawahata; Tomoyuki Yamaguchi; Makoto Otsu; Naoshi Obara; Mamiko Sakata-Yanagimoto; Ken Ishiyama; Hiraku Mori; Florian Nolte; Wolf-Karsten Hofmann; Shuichi Miyawaki; Sumio Sugano; Claudia Haferlach; H. Phillip Koeffler; Lee-Yung Shih; Torsten Haferlach; Shigeru Chiba; Hiromitsu Nakauchi; Satoru Miyano; Seishi Ogawa

  NATURE, 2011年10月, 査読有り

  
• Aberrations of NEGR1 on 1p31 and MYEOV on 11q13 in neuroblastoma

  Junko Takita; Yuyan Chen; Jun Okubo; Masashi Sanada; Masatoki Adachi; Kentaro Ohki; Riki Nishimura; Ryoji Hanada; Takashi Igarashi; Yasuhide Hayashi; Seishi Ogawa

  CANCER SCIENCE, 2011年09月, 査読有り

  
• Novel CUX1 missense mutation in association with 7q-at leukemic transformation of MPN

  Nils H. Thoennissen; Terra Lasho; Gabriela B. Thoennissen; Seishi Ogawa; Ayalew Tefferi; H. Phillip Koeffler

  AMERICAN JOURNAL OF HEMATOLOGY, 2011年08月, 査読有り

  
• "Arima syndrome and bilateral retinoblastoma in interstitial deletion of 13q14.13-q32.3": Where is the molar tooth sign? Reply

  Kan Takahashi; Akira Oka; Masashi Mizuguchi; Makiko Saitoh; Junko Takita; Atsushi Sato; Masakazu Mimaki; Motohiro Kato; Seishi Ogawa; Takashi Igarashi

  BRAIN & DEVELOPMENT, 2011年05月, 査読有り

  
• Interstitial deletion of 13q14.13-q32.3 presenting with Arima syndrome and bilateral retinoblastoma

  Kan Takahashi; Akira Oka; Masashi Mizuguchi; Makiko Saitoh; Junko Takita; Atsushi Sato; Masakazu Mimaki; Motohiro Kato; Seishi Ogawa; Takashi Igarashi

  BRAIN & DEVELOPMENT, 2011年04月, 査読有り

  
• MYC Amplification as a Prognostic Marker of Early-Stage Lung Adenocarcinoma Identified by Whole Genome Copy Number Analysis

  Reika Iwakawa; Takashi Kohno; Motohiro Kato; Kouya Shiraishi; Koji Tsuta; Masayuki Noguchi; Seishi Ogawa; Jun Yokota

  CLINICAL CANCER RESEARCH, 2011年03月, 査読有り

  
• Oncogenic mutations of ALK in neuroblastoma

  Seishi Ogawa; Junko Takita; Masashi Sanada; Yasuhide Hayashi

  CANCER SCIENCE, 2011年02月, 査読有り

  
• IDH1 and IDH2 mutations are rare in pediatric myeloid malignancies

  K. Oki; J. Takita; M. Hiwatari; R. Nishimura; M. Sanada; J. Okubo; M. Adachi; M. Sotomatsu; A. Kikuchi; T. Igarashi; Y. Hayashi; S. Ogawa

  LEUKEMIA, 2011年02月, 査読有り

  
• [108th Scientific Meeting of the Japanese Society of Internal Medicine: educational lecture: 17. Molecular pathogenesis of B cell lymphoma].

  S. Ogawa

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2011年, 査読有り

  
• [Gain-of-function mutation of c-CBL tumor suppressor gene in myeloid neoplasms].

  S. Ogawa

  [Rinshō ketsueki] The Japanese journal of clinical hematology, 2011年, 査読有り

  
• [Significance of A20 in B-cell lymphomas].

  M. Kato; S. Ogawa

  [Rinshō ketsueki] The Japanese journal of clinical hematology, 2011年, 査読有り

  
• A nonsense mutation of IDH1 in myelodysplastic syndromes and related disorders

  K. Yoshida; M. Sanada; M. Kato; R. Kawahata; A. Matsubara; J. Takita; L-Y Shih; H. Mori; H. P. Koeffler; S. Ogawa

  LEUKEMIA, 2011年01月, 査読有り

  
• Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine

  Mamiko Sakata-Yanagimoto; Toru Sakai; Yasuyuki Miyake; Toshiki I. Saito; Haruhiko Maruyama; Yasuyuki Morishita; Etsuko Nakagami-Yamaguchi; Keiki Kumano; Hideo Yagita; Masashi Fukayama; Seishi Ogawa; Mineo Kurokawa; Koji Yasutomo; Shigeru Chiba

  BLOOD, 2011年01月, 査読有り

  
• Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia

  Ryoko Okamoto; Seishi Ogawa; Daniel Nowak; Norihiko Kawamata; Tadayuki Akagi; Motohiro Kato; Masashi Sanada; Tamara Weiss; Claudia Haferlach; Martin Dugas; Christian Ruckert; Torsten Haferlach; H. Phillip Koeffler

  HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010年09月, 査読有り

  
• Deregulated Intracellular Signaling by Mutated c-CBL in Myeloid Neoplasms

  Seishi Ogawa; Lee-Yung Shih; Takahiro Suzuki; Makoto Otsu; Hiromitsu Nakauchi; H. Phillip Koeffler; Masashi Sanada

  CLINICAL CANCER RESEARCH, 2010年08月, 査読有り

  
• The correlation pattern of acquired copy number changes in 164 ETV6/RUNX1-positive childhood acute lymphoblastic leukemias

  Henrik Lilljebjorn; Charlotte Soneson; Anna Andersson; Jesper Heldrup; Mikael Behrendtz; Norihiko Kawamata; Seishi Ogawa; H. Phillip Koeffler; Felix Mitelman; Bertil Johansson; Magnus Fontes; Thoas Fioretos

  HUMAN MOLECULAR GENETICS, 2010年08月, 査読有り

  
• Impact of highly conserved HLA haplotype on acute graft-versus-host disease

  Satoko Morishima; Seishi Ogawa; Aiko Matsubara; Takakazu Kawase; Yasuhito Nannya; Koichi Kashiwase; Masahiro Satake; Hiroo Saji; Hidetoshi Inoko; Shunichi Kato; Yoshihisa Kodera; Takehiko Sasazuki; Yasuo Morishima

  BLOOD, 2010年06月, 査読有り

  
• Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk

  Amy L. Sherborne; Fay J. Hosking; Rashmi B. Prasad; Rajiv Kumar; Rolf Koehler; Jayaram Vijayakrishnan; Elli Papaemmanuil; Claus R. Bartram; Martin Stanulla; Martin Schrappe; Andreas Gast; Sara E. Dobbins; Yussanne Ma; Eamonn Sheridan; Malcolm Taylor; Sally E. Kinsey; Tracey Lightfoot; Eve Roman; Julie A. E. Irving; James M. Allan; Anthony V. Moorman; Christine J. Harrison; Ian P. Tomlinson; Sue Richards; Martin Zimmermann; Csaba Szalai; Agnes F. Semsei; Daniel J. Erdelyi; Maja Krajinovic; Daniel Sinnett; Jasmine Healy; Anna Gonzalez Neira; Norihiko Kawamata; Seishi Ogawa; H. Phillip Koeffler; Kari Hemminki; Mel Greaves; Richard S. Houlston

  NATURE GENETICS, 2010年06月, 査読有り

  
• Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer

  Motohisa Tada; Fumihiko Kanai; Yasuo Tanaka; Masashi Sanada; Yasuhito Nannya; Keisuke Tateishi; Miki Ohta; Yoshinari Asaoka; Motoko Seto; Fumio Imazeki; Haruhiko Yoshida; Seishi Ogawa; Osamu Yokosuka; Masao Omata

  CANCER SCIENCE, 2010年05月, 査読有り

  
• CBL mutations in juvenile myelomonocytic leukemia and pediatric myelodysplastic syndrome

  N. Shiba; M. Kato; M-j Park; M. Sanada; E. Ito; K. Fukushima; M. Sako; H. Arakawa; S. Ogawa; Y. Hayashi

  LEUKEMIA, 2010年05月, 査読有り

  
• Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens

  Edus H. Warren; Nobuharu Fujii; Yoshiki Akatsuka; Colette N. Chaney; Jeffrey K. Mito; Keith R. Loeb; Ted A. Gooley; Michele L. Brown; Kevin K. W. Koo; Kellie V. Rosinski; Seishi Ogawa; Aiko Matsubara; Frederick R. Appelbaum; Stanley R. Riddell

  BLOOD, 2010年05月, 査読有り

  
• Relapse of leukemia with loss of mismatched HLA resulting from uniparental disomy after haploidentical hematopoietic stem cell transplantation

  Itzel Bustos Villalobos; Yoshiyuki Takahashi; Yoshiki Akatsuka; Hideki Muramatsu; Nobuhiro Nishio; Asahito Hama; Hiroshi Yagasaki; Hiroh Saji; Motohiro Kato; Seishi Ogawa; Seiji Kojima

  BLOOD, 2010年04月, 査読有り

  
• Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome-negative myeloproliferative neoplasms

  Nils H. Thoennissen; Utz O. Krug; Dhong Hyun Tony Lee; Norihiko Kawamata; Gabriela B. Iwanski; Terra Lasho; Tamara Weiss; Daniel Nowak; Maya Koren-Michowitz; Motohiro Kato; Masashi Sanada; Lee-Yung Shih; Arnon Nagler; Sophie D. Raynaud; Carsten Mueller-Tidow; Ruben Mesa; Torsten Haferlach; D. Gary Gilliland; Ayalew Tefferi; Seishi Ogawa; H. Phillip Koeffler

  BLOOD, 2010年04月, 査読有り

  
• Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia

  Fumio Nakahara; Mamiko Sakata-Yanagimoto; Yukiko Komeno; Naoko Kato; Tomoyuki Uchida; Kyoko Haraguchi; Keiki Kumano; Yuka Harada; Hironori Harada; Jiro Kitaura; Seishi Ogawa; Mineo Kurokawa; Toshio Kitamura; Shigeru Chiba

  BLOOD, 2010年04月, 査読有り

  
• Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion

  Yoshinari Asaoka; Motohisa Tada; Tsuneo Ikenoue; Motoko Seto; Mitsuho Imai; Koji Miyabayashi; Keisuke Yamamoto; Shinzo Yamamoto; Yotaro Kudo; Dai Mohri; Yoshihiro Isomura; Hideaki Ijichi; Keisuke Tateishi; Fumihiko Kanai; Seishi Ogawa; Masao Omata; Kazuhiko Koike

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2010年04月, 査読有り

  
• Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms

  Seishi Ogawa; Masashi Sanada; Lee-Young Shih; Takahiro Suzuki; Makoto Otsu; Hiromitsu Nakauchi; H. Philip Koeffler

  CELL CYCLE, 2010年03月, 査読有り

  
• SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations

  Daniel Nowak; Seishi Ogawa; Markus Mueschen; Motohiro Kato; Norihiko Kawamata; Antonie Meixel; Verena Nowak; Han S. Kim; Sharon Kang; Ronald Paquette; Mi-Sook Chang; Nils H. Thoenissen; Max Mossner; Wolf-Karsten Hofmann; Alexander Kohlmann; Tamara Weiss; Torsten Haferlach; Claudia Haferlach; H. Phillip Koeffler

  BLOOD, 2010年02月, 査読有り

  
• [Leukemia and lymphoma].

  M. Kato; S. Ogawa

  Nippon rinsho. Japanese journal of clinical medicine, 2010年, 査読有り

  
• Hepatoblastoma in a Patient with Sotos Syndrome

  Motohiro Kato; Junko Takita; Kan Takahashi; Masakazu Mimaki; Yuyan Chen; Katsuyoshi Koh; Kohmei Ida; Akira Oka; Masashi Mizuguchi; Seishi Ogawa; Takashi Igarashi

  JOURNAL OF PEDIATRICS, 2009年12月, 査読有り

  
• Dual antitumor mechanisms of Notch signaling inhibitor in a T-cell acute lymphoblastic leukemia xenograft model

  Shigeo Masuda; Keiki Kumano; Takahiro Suzuki; Taisuke Tomita; Takeshi Iwatsubo; Hideaki Natsugari; Arinobu Tojo; Makoto Shibutani; Kunitoshi Mitsumori; Yutaka Hanazono; Seishi Ogawa; Mineo Kurokawa; Shigeru Chiba

  CANCER SCIENCE, 2009年12月, 査読有り

  
• Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma

  Tadayuki Akagi; Tetsuo Ito; Motohiro Kato; Zhe Jin; Yulan Chen; Takatsugu Kan; Go Yamamoto; Alexandru Olaru; Norihiko Kawamata; Jessica Boult; Harimik J. Soukiasian; Carl W. Miller; Seishi Ogawa; Stephen J. Meltzer; H. Phillip Koeffler

  INTERNATIONAL JOURNAL OF CANCER, 2009年11月, 査読有り

  
• Single nucleotide polymorphism genomic arrays analysis of t(8;21) acute myeloid leukemia cells

  Tadayuki Akagi; Lee-Yung Shih; Seishi Ogawa; Joachim Gerss; Stephen R. Moore; Rhona Schreck; Norihiko Kawamata; Der-Cherng Liang; Masashi Sanada; Yasuhito Nannya; Stefan Deneberg; Vasilios Zachariadis; Ann Nordgren; Jee Hoon Song; Martin Dugas; Soren Lehmann; H. Phillip Koeffler

  HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009年09月, 査読有り

  
• Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms

  Masashi Sanada; Takahiro Suzuki; Lee-Yung Shih; Makoto Otsu; Motohiro Kato; Satoshi Yamazaki; Azusa Tamura; Hiroaki Honda; Mamiko Sakata-Yanagimoto; Keiki Kumano; Hideaki Oda; Tetsuya Yamagata; Junko Takita; Noriko Gotoh; Kumi Nakazaki; Norihiko Kawamata; Masafumi Onodera; Masaharu Nobuyoshi; Yasuhide Hayashi; Hiroshi Harada; Mineo Kurokawa; Shigeru Chiba; Hiraku Mori; Keiya Ozawa; Mitsuhiro Omine; Hisamaru Hirai; Hiromitsu Nakauchi; H. Phillip Koeffler; Seishi Ogawa

  NATURE, 2009年08月, 査読有り

  
• Identified hidden genomic changes in mantle cell lymphoma using high-resolution single nucleotide polymorphism genomic array

  Norihiko Kawamata; Seishi Ogawa; Saskia Gueller; Samuel H. Ross; Thien Huynh; John Chen; Andrew Chang; Shayan Nabavi-Nouis; Nairi Megrabian; Reiner Siebert; Jose A. Martinez-Climent; H. Phillip Koeffler

  EXPERIMENTAL HEMATOLOGY, 2009年08月, 査読有り

  
• Frequent inactivation of A20 in B-cell lymphomas

  Motohiro Kato; Masashi Sanada; Itaru Kato; Yasuharu Sato; Junko Takita; Kengo Takeuchi; Akira Niwa; Yuyan Chen; Kumi Nakazaki; Junko Nomoto; Yoshitaka Asakura; Satsuki Muto; Azusa Tamura; Mitsuru Iio; Yoshiki Akatsuka; Yasuhide Hayashi; Hiraku Mori; Takashi Igarashi; Mineo Kurokawa; Shigeru Chiba; Shigeo Mori; Yuichi Ishikawa; Koji Okamoto; Kensei Tobinai; Hitoshi Nakagama; Tatsutoshi Nakahata; Tadashi Yoshino; Yukio Kobayashi; Seishi Ogawa

  NATURE, 2009年06月, 査読有り

  
• Derivation of functional mature neutrophils from human embryonic stem cells

  Yasuhisa Yokoyama; Takahiro Suzuki; Mamiko Sakata-Yanagimoto; Keiki Kumano; Katsumi Higashi; Tsuyoshi Takato; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba

  BLOOD, 2009年06月, 査読有り

  
• Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia

  Norihiko Kawamata; Seishi Ogawa; Karl Seeger; Renate Kirschner-Schwabe; Thien Huynh; John Chen; Nairi Megrabian; Jochen Harbott; Martin Zimmermann; Guenter Henze; Martin Schrappe; Claus R. Bartram; H. Phillip Koeffler

  INTERNATIONAL JOURNAL OF ONCOLOGY, 2009年06月, 査読有り

  
• Notch Activation Induces the Generation of Functional NK Cells from Human Cord Blood CD34-Positive Cells Devoid of IL-15

  Kyoko Haraguchi; Takahiro Suzuki; Noriko Koyama; Keiki Kumano; Fumio Nakahara; Akihiko Matsumoto; Yasuhisa Yokoyama; Mamiko Sakata-Yanagimoto; Shigeo Masuda; Tsuyoshi Takahashi; Aki Kamijo; Koki Takahashi; Minoko Takanashi; Yoshiki Okuyama; Koji Yasutomo; Seiji Sakano; Hideo Yagita; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba

  JOURNAL OF IMMUNOLOGY, 2009年05月, 査読有り

  
• HapMap scanning of novel human minor histocompatibility antigens

  Michi Kamei; Yasuhito Nannya; Hiroki Torikai; Takakazu Kawase; Kenjiro Taura; Yoshihiro Inamoto; Taro Takahashi; Makoto Yazaki; Satoko Morishima; Kunio Tsujimura; Koichi Miyamura; Tetsuya Ito; Hajime Togari; Stanley R. Riddell; Yoshihisa Kodera; Yasuo Morishima; Toshitada Takahashi; Kiyotaka Kuzushima; Seishi Ogawa; Yoshiki Akatsuka

  BLOOD, 2009年05月, 査読有り

  
• High-Resolution Genomic Copy Number Profiling of Glioblastoma Multiforme by Single Nucleotide Polymorphism DNA Microarray

  Dong Yin; Seishi Ogawa; Norihiko Kawamata; Patrizia Tunici; Gaetano Finocchiaro; Marica Eoli; Christian Ruckert; Thien Huynh; Gentao Liu; Motohiro Kato; Masashi Sanada; Anna Jauch; Martin Dugas; Keith L. Black; H. Phillip Koeffler

  MOLECULAR CANCER RESEARCH, 2009年05月, 査読有り

  
• Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma

  Suk-young Lee; Keiki Kumano; Kumi Nakazaki; Masashi Sanada; Akihiko Matsumoto; Go Yamamoto; Yasuhito Nannya; Ritsuro Suzuki; Satoshi Ota; Yasunori Ota; Koji Izutsu; Mamiko Sakata-Yanagimoto; Akira Hangaishi; Hideo Yagita; Masashi Fukayama; Masao Seto; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba

  CANCER SCIENCE, 2009年05月, 査読有り

  
• Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy

  Daniel Nowak; Emilie Le Toriellec; Marc-Henri Stern; Norihiko Kawamata; Tadayuki Akagi; Martin J. Dyer; Wolf-Karsten Hofmann; Seishi Ogawa; H. Phillip Koeffler

  HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009年04月, 査読有り

  
• Double minute chromosomes containing MYB gene and NUP214-ABL1 fusion gene in T-cell leukemia detected by single nucleotide polymorphism DNA microarray and fluorescence in situ hybridization

  Norihiko Kawamata; Ling Zhang; Seishi Ogawa; Yasuhito Nannya; Azadeh Dashti; Daning Lu; Stephen Lim; Rhona Schreck; H. Phillip Koeffler

  LEUKEMIA RESEARCH, 2009年04月, 査読有り

  
• HLA mismatch combinations associated with decreased risk of relapse: implications for the molecular mechanism

  Takakazu Kawase; Keitaro Matsuo; Koichi Kashiwase; Hidetoshi Inoko; Hiroh Saji; Seishi Ogawa; Shunichi Kato; Takehiko Sasazuki; Yoshihisa Kodera; Yasuo Morishima

  BLOOD, 2009年03月, 査読有り

  
• Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations

  Tadayuki Akagi; Lee-Yung Shih; Motohiro Kato; Norihiko Kawamata; Go Yamamoto; Masashi Sanada; Ryoko Okamoto; Carl W. Miller; Der-Cherng Liang; Seishi Ogawa; H. Phillip Koeffler

  BLOOD, 2009年02月, 査読有り

  
• Frequent genomic abnormalities in acute myeloid leukemia/myelodysplastic syndrome with normal karyotype

  Tadayuki Akagi; Seishi Ogawa; Martin Dugas; Norihiko Kawamata; Go Yamamoto; Yasuhito Nannya; Masashi Sanada; Carl W. Miller; Amanda Yung; Susanne Schnittger; Torsten Haferlach; Claudia Haferlach; H. Phillip Koeffler

  HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009年02月, 査読有り

  
• Oncogenic mutations of ALK are associated with tumorigenesis of neuroblastoma

  J. Takita; S. Ogawa

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2009年, 査読有り

  
• Exploration of the Genetic Basis of GVHD by Genetic Association Studies

  Seishi Ogawa; Aiko Matsubara; Makoto Onizuka; Koichi Kashiwase; Masashi Sanada; Motohiro Kato; Yasuhito Nannya; Yoshiki Akatsuka; Masahiro Satake; Junko Takita; Shigeru Chiba; Hiroo Saji; Etsuko Maruya; Hidetoshi Inoko; Yasuo Morishima; Yoshihisa Kodera; Sasazuki Takehiko

  BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2009年01月, 査読有り

  
• Genome-Wide Loss of Heterozygosity and Uniparental Disomy in BRCA1/2-Associated Ovarian Carcinomas

  Christine S. Walsh; Seishi Ogawa; Daniel R. Scoles; Carl W. Miller; Norihiko Kawamata; Steven A. Narod; H. Phillip Koeffler; Beth Y. Karlan

  CLINICAL CANCER RESEARCH, 2008年12月, 査読有り

  
• Genetic profiling of myeloproliferative disorders by single-nucleotide polymorphism oligonucleotide microarray

  Norihiko Kawamata; Seishi Ogawa; Go Yamamoto; Soren Lehmann; Ross L. Levine; Yana Pikman; Yasuhito Nannya; Masashi Sanada; Carl W. Miller; D. Gary Gilliland; H. Phillip Koeffler

  EXPERIMENTAL HEMATOLOGY, 2008年11月, 査読有り

  
• Characterization of adenocarcinoma of the lung in a familial adenomatous polyposis patient

  Kazuya Shinmura; Masaya Suzuki; Hidetaka Yamada; Hong Tao; Masanori Goto; Takaharu Kamo; Kiyoko Nagura; Shinji Kageyama; Motohiro Kato; Seishi Ogawa; Masato Maekawa; Kazuya Takamochi; Kazuya Suzuki; Toshio Nakamura; Haruhiko Sugimura

  PATHOLOGY INTERNATIONAL, 2008年11月, 査読有り

  
• Gain of GRHL2 is associated with early recurrence of hepatocellular carcinoma

  Yasuo Tanaka; Fumihiko Kanai; Motohisa Tada; Ryosuke Tateishi; Masashi Sanada; Yasuhito Nannya; Miki Ohta; Yoshinari Asaoka; Motoko Seto; Shuichiro Shiina; Haruhiko Yoshida; Takao Kawabe; Osamu Yokosuka; Seishi Ogawa; Masao Omata

  JOURNAL OF HEPATOLOGY, 2008年11月, 査読有り

  
• Oncogenic mutations of ALK kinase in neuroblastoma

  Yuyan Chen; Junko Takita; Young Lim Choi; Motohiro Kato; Miki Ohira; Masashi Sanada; Lili Wang; Manabu Soda; Akira Kikuchi; Takashi Igarashi; Akira Nakagawara; Yasuhide Hayashi; Hiroyuki Mano; Seishi Ogawa

  NATURE, 2008年10月, 査読有り

  
• Chronic phase of ETV6-ABL1 positive CML responds to imatinib

  Norihiko Kawamata; Azadeh Dashti; Becky Miller; H. Phillip Koeffler

  GENES CHROMOSOMES & CANCER, 2008年10月, 査読有り

  
• Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells

  Susumu Goyama; Go Yamamoto; Munetake Shimabe; Tomohiko Sato; Motoshi Ichikawa; Seishi Ogawa; Shigeru Chiba; Mineo Kurokawa

  CELL STEM CELL, 2008年08月, 査読有り

  
• ERCC5 is a novel biomarker of ovarian cancer prognosis

  Christine S. Walsh; Seishi Ogawa; Hisae Karahashi; Daniel R. Scoles; James C. Pavelka; Hang Tran; Carl W. Miller; Norihiko Kawamata; Charles Ginther; Judy Dering; Masashi Sanada; Yasuhito Nannya; Dennis J. Slamon; H. Phillip Koeffler; Beth Y. Karlan

  JOURNAL OF CLINICAL ONCOLOGY, 2008年06月, 査読有り

  
• AML1-Evi-1 specifically transforms hematopoietic stem cells through fusion of the entire Evi-1 sequence to AML1

  M. Takeshita; M. Ichikawa; E. Nitta; S. Goyama; T. Asai; S. Ogawa; S. Chiba; M. Kurokawa

  LEUKEMIA, 2008年06月, 査読有り

  
• AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis

  Motoshi Ichikawa; Susumu Goyama; Takashi Asai; Masahito Kawazu; Masahiro Nakagawa; Masataka Takeshita; Shigeru Chiba; Seishi Ogawa; Mineo Kurokawa

  JOURNAL OF IMMUNOLOGY, 2008年04月, 査読有り

  
• Identification of human minor histocompatibility antigens based on genetic association with highly parallel genotyping of pooled DNA

  Takakazu Kawase; Yasuhito Nannya; Hiroki Torikai; Go Yamamoto; Makoto Onizuka; Satoko Morishima; Kunio Tsujimura; Koichi Miyamura; Yoshihisa Kodera; Yasuo Morishima; Toshitada Takahashi; Kiyotaka Kuzushima; Seishi Ogawa; Yoshiki Akatsuka

  BLOOD, 2008年03月, 査読有り

  
• Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia

  Soeren Lehmann; Seishi Ogawa; Sophie D. Raynaud; Masashi Sanada; Yasuhito Nannya; Michel Ticchioni; Christian Bastard; Norihiko Kawamata; H. Phillip Koeffler

  CANCER, 2008年03月, 査読有り

  
• Whole-genome profiling of chromosomal aberrations in hepatoblastoma using high-density single-nucleotide polymorphism genotyping microarrays

  Makoto Suzuki; Motohiro Kato; Chen Yuyan; Junko Takita; Masashi Sanada; Yasuhito Nannya; Go Yamamoto; Atsushi Takahashi; Hitoshi Ikeda; Hiroyuki Kuwano; Seishi Ogawa; Yasuhide Hayashi

  CANCER SCIENCE, 2008年03月, 査読有り

  
• Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis

  Keiki Kumano; Shigeo Masuda; Masataka Sata; Toshiki Saito; Suk-young Lee; Mamiko Sakata-Yanagimoto; Taisuke Tomita; Takeshi Iwatsubo; Hideaki Natsugari; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba

  PIGMENT CELL & MELANOMA RESEARCH, 2008年02月, 査読有り

  
• Genetic profiling of myeloproliferative disorders by single-nucleotide polymorphism oligonucleotide microarray

  N. Kawamata; S. Ogawa; G. Yamamoto; S. Lehmann; R.L. Levine; Y. Pikman; Y. Nannya; M. Sanada; C.W. Miller; D.G. Gilliland; H.P. Koeffler

  Experimental Hematology, 2008年, 査読有り

  
• Integrated analysis of copy number alterations and loss of heterozygosity in human pancreatic cancer using a high-resolution, single nucleotide polymorphism array

  Lian-Jie Lin; Yoshinari Asaoka; Motohisa Tada; Masashi Sanada; Yasuhito Nannya; Yasuo Tanaka; Keisuke Tateishi; Miki Ohta; Motoko Seto; Naoki Sasahira; Minoru Tada; Takao Kawabe; Chang-Qing Zheng; Fumihiko Kanai; Seishi Ogawa; Masao Omata

  ONCOLOGY, 2008年, 査読有り

  
• Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray

  Norihiko Kawamata; Seishi Ogawa; Martin Zimmermann; Motohiro Kato; Masashi Sanada; Kari Hemminki; Go Yamatomo; Yasuhito Nannya; Rolf Koehler; Thomas Flohr; Carl W. Miller; Jochen Harbott; Wolf-Dieter Ludwig; Martin Stanulla; Martin Schrappe; Claus R. Bartram; H. Phillip Koeffler

  BLOOD, 2008年01月, 査読有り

  
• Donor Killer Immunoglobulin-Like Receptor (KIR) Genotype-Patient Cognate KIR Ligand Combination and Antithymocyte Globulin Preadministration Are Critical Factors in Outcome of HLA-C-KIR Ligand-Mismatched T Cell-Replete Unrelated Bone Marrow Transplantatio

  T. Yabe; K. Matsuo; K. Hirayasu; K. Kashiwase; S. Kawamura-Ishii; H. Tanaka; A. Ogawa; M. Takanashi; M. Satake; K. Nakajima; K. Tokunaga; H. Inoko; H. Saji; S. Ogawa; T. Juji; T. Sasazuki; Y. Kodera; Y. Morishima

  Biology of Blood and Marrow Transplantation, 2008年01月, 査読有り

  
• Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development

  Masahito Kawazu; Go Yamamoto; Mayumi Yoshimi; Kazuki Yamamoto; Takashi Asai; Motoshi Ichikawa; Sachiko Seo; Masahiro Nakagawa; Shigeru Chiba; Mineo Kurokawa; Seishi Ogawa

  JOURNAL OF IMMUNOLOGY, 2007年10月, 査読有り

  
• Evaluation of genome-wide power of genetic association studies based on empirical data from the HapMap project

  Yasuhito Nannya; Kenjiro Taura; Mineo Kurokawa; Shigeru Chiba; Seishi Ogawa

  HUMAN MOLECULAR GENETICS, 2007年10月, 査読有り

  
• Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen

  Takakazu Kawase; Yoshiki Akatsuka; Hiroki Torikai; Satoko Morishima; Akira Oka; Akane Tsujimura; Mikinori Miyazaki; Kunio Tsujimura; Koichi Miyamura; Seishi Ogawa; Hidetoshi Inoko; Yasuo Morishima; Yoshihisa Kodera; Kiyotaka Kuzushima; Toshitada Takahashi

  BLOOD, 2007年08月, 査読有り

  
• Single nucleotide polymorphism array analysis of chromosomal instability patterns discriminates rectal adenomas from carcinomas

  E. H. Lips; E. J. de Graaf; R. A. E. M. Tollenaar; R. van Eijk; J. Oosting; K. Szuhai; T. Karsten; Y. Nanya; S. Ogawa; C. J. van de Velde; P. H. C. Eilers; Tom van Wezel; H. Morreau

  JOURNAL OF PATHOLOGY, 2007年07月, 査読有り

  
• Highly sensitive method for genomewide detection of allelic composition in nonpaired, primary tumor specimens by use of affymetrix single-nucleotide-polymorphism genotyping microarrays

  Go Yamamoto; Yasuhito Nannya; Motohiro Kato; Masashi Sanada; Ross L. Levine; Norihiko Kawamata; Akira Hangaishi; Mineo Kurokawa; Shigeru Chiba; D. Gary Gilliland; H. Phillip Koeffler; Seishi Ogawa

  AMERICAN JOURNAL OF HUMAN GENETICS, 2007年07月, 査読有り

  
• Unbalanced translocation der(1;7)(q10; p10) defines a unique clinicopathological subgroup of myeloid neoplasms

  M. Sanada; N. Uike; K. Ohyashiki; K. Ozawa; W. Lili; A. Hangaishi; Y. Kanda; S. Chiba; M. Kurokawa; M. Omine; K. Mitani; S. Ogawa

  LEUKEMIA, 2007年05月, 査読有り

  
• Immunotherapy against metastatic renal cell carcinoma with mature dendritic cells

  Akihiko Matsumoto; Kyoko Haraguchi; Tsuyoshi Takahashi; Takeshi Azuma; Yoshinobu Kanda; Kyoichi Tomita; Mineo Kurokawa; Seishi Ogawa; Koki Takahashi; Shigeru Chiba; Tadaichi Kitamura

  INTERNATIONAL JOURNAL OF UROLOGY, 2007年04月, 査読有り

  
• Genome-wide, high-resolution detection of copy number, loss of heterozygosity, and genotypes from formalin-fixed, paraffin-embedded tumor tissue using microarrays

  Sharoni Jacobs; Ella R. Thompson; Yasuhito Nannya; Go Yamamoto; Raji Pillai; Seishi Ogawa; Dione K. Bailey; Ian G. Campbell

  CANCER RESEARCH, 2007年03月, 査読有り

  
• Effects of HLA allele and killer immunoglobulin-like receptor ligand matching on clinical outcome in leukemia patients undergoing transplantation with T-cell-replete marrow from an unrelated donor

  Yasuo Morishima; Toshio Yabe; Keitaro Matsuo; Koichi Kashiwase; Hidetoshi Inoko; Hiroh Saji; Ken Yamamoto; Etsuko Maruya; Yoshiki Akatsuka; Makoto Onizuka; Hisashi Sakamaki; Hiroshi Sao; Seishi Ogawa; Shunichi Kato; Takeo Juji; Takehiko Sasazuki; Yoshihisa Kodera

  BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2007年03月, 査読有り

  
• Long-term sustained mixed chimerism after allogeneic stem cell transplantation in a patient with severe aplastic anemia

  Akiko M. Saito; Shigeru Chiba; Seishi Ogawa; Yoshinobu Kanda; Hisamaru Hirai; Mineo Kurokawa

  INTERNAL MEDICINE, 2007年, 査読有り

  
• Genome-wide copy number analysis on GeneChip® platform using copy number analyzer for affymetrix GeneChip 2.0 software

  S. Ogawa; Y. Nanya; G. Yamamoto

  Methods in Molecular Biology, 2007年, 査読有り

  
• Corrigendum to "Antineoplastic effect of a single oral dose of the novel Flt3 inhibitor KRN383 on xenografted human leukemic cells harboring Flt3-activating mutations" [Leuk. Res. 30 (2006) 1541-1546] (DOI:10.1016/j.leukres.2006.02.028)

  U. Nishiyama; T. Yoshino; M. Ozai; R. Yoshioka; M. Fujisawa; Y. Ogasawara; M. Kitahori; E. Yoshioka; K. Kubo; Y. Komeno; M. Kurokawa; S. Ogawa; S. Chiba; T. Osawa; T. Kuwaki; H. Hirai; A. Miwa

  Leukemia Research, 2007年, 査読有り

  
• Antineoplastic effect of a single oral dose of the novel Flt3 inhibitor KRN383 on xenografted human leukemic cells harboring F10-activating mutations

  Uichi Nishiyama; Tetsuya Yoshino; Masako Ozai; Rieko Yoshioka; Motoko Fujisawa; Yuko Ocasawara; Miyuki Kitahori; Eiji Yoshioka; Kazuo Kubo; Yukiko Komeno; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba; Tatsushi Osawa; Tomoaki Kuwaki; Hisamaru Hirai; Atsushi Miwa

  LEUKEMIA RESEARCH, 2006年12月, 査読有り

  
• Highly efficient ex vivo expansion of human hematopoietic stem cells using Delta1-Fc chimeric protein

  Takahiro Suzuki; Yasuhisa Yokoyama; Keiki Kumano; Minoko Takanashi; Shiro Kozuma; Tsuyoshi Takato; Tatsutoshi Nakahata; Mitsuo Nishikawa; Seiji Sakano; Mineo Kurokawa; Seishi Ogawa; Shigeru Chiba

  STEM CELLS, 2006年11月, 査読有り

  
• AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis

  Masahiro Nakagawa; Motoshi Ichikawa; Keiki Kumano; Susumu Goyama; Masahito Kawazu; Takashi Asai; Seishi Ogawa; Mineo Kurokawa; Shigeru Chiba

  BLOOD, 2006年11月, 査読有り

  
• Pharmacokinetics of alemtuzumab after haploidentical HLA-mismatched hematopoietic stem cell transplantation using in vivo alemtuzumab with or without CD52-positive malignancies

  Kumi Oshima; Yoshinobu Kanda; Fumio Nakahara; Eriko Shoda; Takahiro Suzuki; Yoichi Imai; Takuro Watanabe; Takashi Asai; Koji Izutsu; Seishi Ogawa; Toru Motokura; Shigeru Chiba; Mineo Kurokawa

  AMERICAN JOURNAL OF HEMATOLOGY, 2006年11月, 査読有り

  
• CD1d expression level in tumor cells is an important determinant for anti-tumor immunity by natural killer T cells

  Kyoko Haraguchi; Tsuyoshi Takahashi; Fumio Nakahara; Akihiko Matsumoto; Mineo Kurokawa; Seishi Ogawa; Hideaki Oda; Hisamaru Hirai; Shigeru Chiba

  LEUKEMIA & LYMPHOMA, 2006年10月, 査読有り

  
• Influence of glutathione S-transferase A1 polymorphism on the phartnacokinetics of busulfan

  M Kusama; T Kubota; Y Matsukura; K Matsuno; S Ogawa; Y Kanda; T Iga

  CLINICA CHIMICA ACTA, 2006年06月, 査読有り

  
• Genomewide screening of DNA copy number changes in chronic myelogenous leukemia with the use of high-resolution array-based comparative genomic hybridization

  N Hosoya; M Sanada; Y Nannya; K Nakazaki; LL Wang; A Hangaishi; M Kurokawa; S Chiba; S Ogawa

  GENES CHROMOSOMES & CANCER, 2006年05月, 査読有り

  
• Hematopoietic stem cells expanded by fibroblast growth factor-1 are excellent targets for retrovirus-mediated gene delivery

  A Crcareva; T Saito; A Kunisato; K Kumano; T Suzuki; M Sakata-Yanagimoto; M Kawazu; A Stojanovic; M Kurokawa; S Ogawa; H Hirai; S Chiba

  EXPERIMENTAL HEMATOLOGY, 2005年12月, 査読有り

  
• Cardiac complications after haploidentical HLA-mismatched hematopoietic stem cell transplantation using in vivo alemtuzumab

  K Oshima; M Sakata-Yanagimoto; Y Asano-Mori; K Izutsu; T Watanabe; E Shoda; S Ogawa; T Motokura; S Chiba; M Kurokawa; H Hirai; Y Kanda

  BONE MARROW TRANSPLANTATION, 2005年11月, 査読有り

  
• Assessment of the International Prognostic Scoring System for determining chemotherapeutic indications in myelodysplastic syndrome: Japanese retrospective multicenter study

  Y Ito; K Ohyashiki; H Hirai; S Ogawa; K Mitani; T Hotta; M Bessho; T Naoe; H Mizoguchi; T Uchiyama; M Omine

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2005年10月, 査読有り

  
• Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance

  S Seo; T Asai; T Saito; T Suzuki; Y Morishita; T Nakamoto; M Ichikawa; G Yamamoto; M Kawazu; T Yamagata; R Sakai; K Mitani; S Ogawa; M Kurokawa; S Chiba; H Hirai

  JOURNAL OF IMMUNOLOGY, 2005年09月, 査読有り

  
• Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP

  E Nitta; K Izutsu; Y Yamaguchi; Y Imai; S Ogawa; S Chiba; M Kurokawa; H Hirai

  ONCOGENE, 2005年09月, 査読有り

  
• Host-residual invariant NK T cells attenuate graft-versus-host immunity

  K Haraguchi; T Takahashi; A Matsumoto; T Asai; Y Kanda; M Kurokawa; S Ogawa; H Oda; M Taniguchi; T Hirai; S Chiba

  JOURNAL OF IMMUNOLOGY, 2005年07月, 査読有り

  
• A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays

  Y Nannya; M Sanada; K Nakazaki; N Hosoya; LL Wang; A Hangaishi; M Kurokawa; S Chiba; DK Bailey; GC Kennedy; S Ogawa

  CANCER RESEARCH, 2005年07月, 査読有り

  
• Identification of Ki23819, a highly potent inhibitor of kinase activity of mutant FLT3 receptor tyrosine kinase

  Y Komeno; M Kurokawa; Y Imai; M Takeshita; T Matsumura; K Kubo; T Yoshino; U Nishiyama; T Kuwaki; K Kubo; T Osawa; S Ogawa; S Chiba; A Miwa; H Hirai

  LEUKEMIA, 2005年06月, 査読有り

  
• Notch 1 oncoprotein antagonizes TGF-β/Smad-mediated cell growth suppression via sequestration of coactivator p300

  S. Masuda; K. Kumano; K. Shimizu; Y. Imai; M. Kurokawa; S. Ogawa; M. Miyagishi; K. Taira; H. Hirai; S. Chiba

  Cancer Science, 2005年05月, 査読有り

  
• In vivo alemtuzumab enables haploidentical human leukocyte antigen-mismatched hematopoietic stem-cell transplantation without ex vivo graft manipulation

  Y Kanda; K Oshima; Y Asano-Mori; K Kandabashi; M Nakagawa; M Sakata-Yanagimoto; K Izutsu; A Hangaishi; S Tsujino; S Ogawa; T Motokura; S Chiba; H Hirai

  TRANSPLANTATION, 2005年05月, 査読有り

  
• Graft-versus-tumor effect against advanced pancreatic cancer after allogeneic reduced-intensity stem cell transplantation

  Y Kanda; Y Komatsu; M Akahane; S Kojima; Y Asano-Mori; M Tada; K Oshima; H Isayama; S Ogawa; T Motokura; S Chiba; K Ohtomo; M Omata; H Hirai

  TRANSPLANTATION, 2005年04月, 査読有り

  
• Functional domains of Runx1 are differentially required for CD4 repression, TCRβ expression, and CD4/8 double-negative to CD4/8 double-positive transition in thymocyte development

  M. Kawazu; T. Asai; M. Ichikawa; G. Yamamoto; T. Saito; S. Goyama; K. Mitani; K. Miyazono; S. Chiba; S. Ogawa; M. Kurokawa; H. Hirai

  Journal of Immunology, 2005年03月, 査読有り

  
• Identification of a SRC-like tyrosine kinase gene, FRK, fused with ETV6 in a patient with acute myelogenous leukemia carrying a t(6;12)(q21;p13) translocation

  N Hosoya; Y Qiao; A Hangaishi; LL Wang; Y Nannya; M Sanada; M Kurokawa; S Chiba; H Hirai; S Ogawa

  GENES CHROMOSOMES & CANCER, 2005年03月, 査読有り

  
• A prospective trial to evaluate the safety and efficacy of pravastatin for the treatment of refractory chronic graft-versus-host disease

  A Hori; Y Kanda; S Goyama; Y Onishi; Y Komeno; K Mitani; Y Kishi; S Ogawa; O Imataki; S Chiba; R Kojima; T Hamaki; M Sakiyama; M Kami; A Makimoto; R Tanosaki; Y Takaue; H Hirai

  TRANSPLANTATION, 2005年02月, 査読有り

  
• Genetic abnormalities in myelodysplastic syndrome

  S. Ogawa

  [Rinsh¿ ketsueki] The Japanese journal of clinical hematology., 2005年, 査読有り

  
• Genetic analysis of hematopoietic neoplasms

  S. Ogawa

  Nippon rinsho. Japanese journal of clinical medicine, 2005年, 査読有り

  
• Mutations of the Notch1 gene in T-cell acute lymphoblastic leukemia: Analysis in adults and children [4]

  S.-Y. Lee; K. Kumano; S. Masuda; A. Hangaishi; J. Takita; K. Nakazaki; M. Kurokawa; Y. Hayashi; S. Ogawa; S. Chiba

  Leukemia, 2005年, 査読有り

  
• SCL/Tal1 and lymphoid versus myeloid lineage assignment [1] (multiple letters)

  M. Hall; D. Curtis; A. Kunisato; S. Ogawa; S. Chiba

  Blood, 2005年, 査読有り

  
• The transcriptionafly active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region

  S Goyama; Y Yamaguchi; Y Imai; M Kawazu; M Nakagawa; T Asai; K Kumano; K Mitani; S Ogawa; S Chiba; M Kurokawa; H Hirai

  BLOOD, 2004年12月, 査読有り

  
• Clinical significance of peripheral blood erythroblastosis after hematopoietic stem cell transplantation

  S Goyama; Y Kanda; Y Nannya; S Ogawa; Y Asano-Moki; N Ogawa; M Nakagawa; M Sakata-Yanagimoto; M Kawazu; Y Komeno; Y Imai; A Hangaishi; M Kurokawa; S Tsujino; K Aoki; S Chiba; T Motokura; H Hirai

  LEUKEMIA & LYMPHOMA, 2004年12月, 査読有り

  
• Immature granulocyte fraction in the peripheral blood is a practical indicator for mobilization of CD34(+) cells

  M Endo-Matsubara; S Ogawa; K Sasaki; T Takahashi; S Chiba; H Hirai

  AMERICAN JOURNAL OF HEMATOLOGY, 2004年11月, 査読有り

  
• Recovery of Vα24⁺ NKT cells after hematopoietic stem cell transplantation

  K. Haraguchi; T. Takahashi; K. Hiruma; Y. Kanda; Y. Tanaka; S. Ogawa; S. Chiba; O. Miura; H. Sakamaki; H. Hirai

  Bone Marrow Transplantation, 2004年10月, 査読有り

  
• Runx1/AML-1 ranks as a master regulator of adult hematopoiesis

  M Ichikawa; T Asai; S Chiba; M Kurokawa; S Ogawa

  CELL CYCLE, 2004年06月, 査読有り

  
• Prospective comparison of the diagnostic potential of real-time PCR, double-sandwich enzyme-linked immunosorbent assay for galactomannan, and a (1→3)-β-D-glucan test in weekly screening for invasive aspergillosis in patients with hematological disorders

  M. Kawazu; Y. Kanda; Y. Nannya; K. Aoki; M. Kurokawa; S. Chiba; T. Motokura; H. Hirai; S. Ogawa

  Journal of Clinical Microbiology, 2004年06月, 査読有り

  
• Predictors for severe cardiac complications after hematopoietic stem cell transplantation

  M Sakata-Yanagimoto; Y Kanda; M Nakagawa; Y Asano-Mori; K Kandabashi; K Izutsu; Y Imai; A Hangaishi; M Kurokawa; S Tsujino; S Ogawa; S Chiba; T Motokura; H Hirai

  BONE MARROW TRANSPLANTATION, 2004年05月, 査読有り

  
• AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues

  Y Yamaguchi; M Kurokawa; Y Imai; K Izutsu; T Asai; M Ichikawa; G Yamamoto; E Nitta; T Yamagata; K Sasaki; K Mitani; S Ogawa; S Chiba; H Hirai

  JOURNAL OF BIOLOGICAL CHEMISTRY, 2004年04月, 査読有り

  
• AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

  M Ichikawa; T Asai; T Saito; G Yamamoto; S Seo; Yamazaki, I; T Yamagata; K Mitani; S Chiba; H Hirai; S Ogawa; M Kurokawa

  NATURE MEDICINE, 2004年03月, 査読有り

  
• Increased incidence of acute graft-versus-host disease with the continuous infusion of cyclosporine A compared to twice-daily infusion

  N Ogawa; Y Kanda; M Matsubara; Y Asano; M Nakagawa; M Sakata-Yanagimoto; K Kandabashi; K Izutsu; Y Imai; A Hangaishi; M Kurokawa; S Tsujino; S Ogawa; K Aoki; S Chiba; T Motokura; H Hirai

  BONE MARROW TRANSPLANTATION, 2004年03月, 査読有り

  
• Ischemic colitis as a manifestation of thrombotic microangiopathy following bone marrow transplantation

  Y Komeno; S Ogawa; T Ishida; K Takeuchi; S Tsujino; M Kurokawa; K Aoki; Y Kanda; S Chiba; T Motokura; M Fukayama; H Hirai

  INTERNAL MEDICINE, 2003年12月, 査読有り

  
• Molecular cytogenetic analyses of HIG, a novel human cell line carrying t(1;3)(p36.3;q25.3) established from a patient with chronic myelogenous leukemia in blastic crisis

  N Hosoya; S Ogawa; T Motokura; A Hangaishi; LL Wang; Y Qiao; Y Nannya; M Kogi; H Hirai

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 2003年12月, 査読有り

  
• Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation

  Y Asano; Y Kanda; N Ogawa; M Sakata-Yanagimoto; M Nakagawa; M Kawazu; S Goyama; K Kandabashi; K Izutsu; Y Imai; A Hangaishi; M Kurokawa; S Tsujino; S Ogawa; K Aoki; S Chiba; T Motokura; H Hirai

  BONE MARROW TRANSPLANTATION, 2003年12月, 査読有り

  
• Molecular characterization of the recurrent unbalanced translocation der(1;7)(q10;p10)

  LL Wang; S Ogawa; A Hangaishi; Y Qiao; N Hosoya; Y Nanya; K Ohyashiki; H Mizoguchi; H Hirai

  BLOOD, 2003年10月, 査読有り

  
• Identification of a novel fusion gene, TTL, fused to ETV6 in acute lymphoblastic leukemia with t(12;13)(p13;q14), and its implication in leukemogenesis

  Y Qiao; S Ogawa; A Hangaishi; K Yuji; K Izutsu; A Kunisato; Y Imai; L Wang; N Hosoya; Y Nannya; Y Sato; K Maki; K Mitani; H Hirai

  LEUKEMIA, 2003年06月, 査読有り

  
• Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells

  K Kumano; S Chiba; A Kunisato; M Sata; T Saito; E Nakagami-Yamaguchi; T Yamaguchi; S Masuda; K Shimizu; T Takahashi; S Ogawa; Y Hamada; H Hirai

  IMMUNITY, 2003年05月, 査読有り

  
• Reduced-intensity bone marrow transplantation from an alternative unrelated donor for myelodysplastic syndrome of first-donor origin

  Y Komeno; Y Kanda; K Kandabashi; M Kawazu; S Goyama; M Takeshita; Y Nannya; M Niino; T Nakamoto; M Kurokawa; S Tsujino; S Ogawa; K Aoki; S Chiba; T Motokura; H Hirai

  AMERICAN JOURNAL OF HEMATOLOGY, 2003年03月, 査読有り

  
• A case with myositis as a manifestation of chronic graft-versus-host-disease (GVHD) with severe muscle swelling developed after aggressive muscular exercise

  S. Kano; J. Shimizu; T. Mikata; T. Shinoe; H. Ota; Y. Komeno; S. Ogawa; H. Hirai; I. Kanazawa

  Clinical Neurology, 2003年, 査読有り

  
• Should young patients with e19a2 type BCR/ABL rearrangement undergo stem cell transplantation?

  F Nakamura; S Ogawa; K Izutsu; Y Imai; K Maki; T Yamagata; K Mitani; H Hirai

  LEUKEMIA & LYMPHOMA, 2003年, 査読有り

  
• Rapid diagnosis of invasive pulmonary aspergillosis by quantitative polymerase chain reaction using bronchial lavage fluid

  M Kawazu; Y Kanda; S Goyama; M Takeshita; Y Nannya; M Niino; Y Komeno; T Nakamoto; M Kurokawa; S Tsujino; S Ogawa; K Aoki; S Chiba; T Motokura; N Ohishi; H Hirai

  AMERICAN JOURNAL OF HEMATOLOGY, 2003年01月, 査読有り

  
• Reverse seroconversion of hepatitis B virus after hematopoietic stem cell transplantation

  S Goyama; Y Kanda; Y Nannya; M Kawazu; M Takeshita; M Niino; Y Komeno; T Nakamoto; M Kurokawa; S Tsujino; S Ogawa; K Aoki; S Chiba; T Motokura; Y Shiratori; H Hirai

  LEUKEMIA & LYMPHOMA, 2002年11月, 査読有り

  
• N-ras and p53 gene mutations in Japanese patients with myeloproliferative disorders

  S Tsurumi; Y Nakamura; K Maki; M Omine; K Fujita; T Okamura; Y Niho; S Hashimoto; K Kanno; K Suzuki; A Hangaishi; S Ogawa; H Hirai; K Mitani

  AMERICAN JOURNAL OF HEMATOLOGY, 2002年10月, 査読有り

  
• Transplantation for accidental acute high-dose total body neutron- and γ-radiation exposure

  S. Chiba; A. Saito; S. Ogawa; K. Takeuchi; K. Kumano; S. Seo; T. Suzuki; Y. Tanaka; T. Saito; K. Izutsu; K. Yuji; S. Masuda; S. Futami; M. Nishida; G. Suzuki; R.P. Gale; M. Fukayama; K. Maekawa; H. Hirai

  Bone Marrow Transplantation, 2002年06月, 査読有り

  
• MICAL, a novel CasL interacting molecule, associates with vimentin

  T Suzuki; T Nakamoto; S Ogawa; S Seo; T Matsumura; K Tachibana; C Morimoto; H Hirai

  JOURNAL OF BIOLOGICAL CHEMISTRY, 2002年04月, 査読有り

  
• Generation of Fas-independent CD4+cytotoxic T-cell clone specific for p190 minor bcr-abl fusion peptide

  Y Tanaka; T Takahashi; M Nieda; S Masuda; K Kashiwase; T Takahashi; S Ogawa; S Chiba; T Juji; H Hirai

  LEUKEMIA RESEARCH, 2002年03月, 査読有り

  
• Mutational analyses of the AML1 gene in patients with myelodysplastic syndrome

  Y Imai; M Kurokawa; K Izutsu; A Hangaishi; K Maki; S Ogawa; S Chiba; K Mitani; H Hirai

  LEUKEMIA & LYMPHOMA, 2002年03月, 査読有り

  
• Use of real-time PCR on blood samples for diagnosis of invasive aspergillosis

  M Kami; T Fukui; S Ogawa; Y Kazuyama; U Machida; Y Tanaka; Y Kanda; T Kashima; Y Yamazaki; T Hamaki; S Mori; H Akiyama; Y Mutou; H Sakamaki; K Osumi; S Kimura; H Hirai

  CLINICAL INFECTIOUS DISEASES, 2001年11月, 査読有り

  
• Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis

  Y Imai; M Kurokawa; K Izutsu; A Hangaishi; K Maki; S Ogawa; S Chiba; K Mitani; H Hirai

  ONCOGENE, 2001年01月, 査読有り

  
• Real-time automated PCR for early diagnosis and monitoring of cytomegalovirus infection after bone marrow transplantation

  U Machida; M Kami; T Fukui; Y Kazuyama; M Kinoshita; Y Tanaka; Y Kanda; S Ogawa; H Honda; S Chiba; K Mitani; Y Muto; K Osumi; S Kimura; H Hirai

  JOURNAL OF CLINICAL MICROBIOLOGY, 2000年07月, 査読有り

  
• Computed tomographic scan of the chest, latex agglutination test and plasma (1→3)-β-D-glucan assay in early diagnosis of invasive pulmonary aspergillosis: A prospective study of 215 patients

  M. Kami; Y. Tanaka; Y. Kanda; S. Ogawa; T. Masumoto; K. Ohtomo; T. Matsumura; T. Saito; U. Machida; T. Kashima; H. Hirai

  Haematologica, 2000年07月, 査読有り

  
• The Evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death

  M Kurokawa; K Mitani; T Yamagata; T Takahashi; K Izutsu; S Ogawa; T Moriguchi; E Nishida; Y Yazaki; H Hirai

  EMBO JOURNAL, 2000年06月, 査読有り

  
• Generation of HLA-DRB1*1501-restricted p190 minor bcr-abl (ela2)-specific CD4(+) T lymphocytes

  Y Tanaka; T Takahashi; M Nieda; S Masuda; K Kashiwase; S Ogawa; S Chiba; T Juji; H Hirai

  BRITISH JOURNAL OF HAEMATOLOGY, 2000年05月, 査読有り

  
• CIZ, a zinc finger protein that interacts with p130(cas) and activates the expression of matrix metalloproteinases

  T Nakamoto; T Yamagata; R Sakai; S Ogawa; H Honda; H Ueno; N Hirano; Y Yazaki; H Hirai

  MOLECULAR AND CELLULAR BIOLOGY, 2000年03月, 査読有り

  
• Mutations of a checkpoint gene, Chk2, in primary hematopoietic malignancies

  A. Hangaishi; S. Ogawa; Q. Ying

  Blood, 2000年, 査読有り

  
• Essential thrombocythemia in transformation from myelodysplastic syndrome to acute myeloid leukemia with inv(3) after treatment for gastric cancer

  M. Horikoshi; U. Machida; M. Itikawa; S. Seo; S. Masuda; M. Kurokawa; S. Ogawa; S. Sunaga; H. Honda; K. Aoki; S. Chiba; K. Mitani; H. Hirai; Y. Yazaki

  [Rinsho ketsueki] The Japanese journal of clinical hematology, 2000年, 査読有り

  
• Hyperacute graff-versus-host disease and NKT cells [3]

  Y. Tanaka; M. Kami; S. Ogawa; U. Machida; T. Takahashi; M. Ichikawa; K. Yuji; K. Izutsu; T. Asai; Y. Kanda; H. Honda; K. Mitani; S. Chiba; H. Hirai; Y. Yazaki; M. Sasaki; K. Sasaki; S. Mineishi

  American Journal of Hematology, 2000年, 査読有り

  
• Molecular characterization of the genomic breakpoints in a case of t(3;21)(q26;q22)

  H Hirai; S Ogawa; M Kurokawa; Y Yazaki; K Mitani

  GENES CHROMOSOMES & CANCER, 1999年09月, 査読有り

  
• Increased serum soluble Fas ligand associated with recurrent B-cell non-Hodgkin's lymphoma after autologous peripheral blood stem cell transplantation

  Y Kanda; S Chiba; Y Tanaka; M Kami; T Saito; K Izutsu; T Asai; K Yuji; S Ogawa; H Honda; K Mitani; K Usuki; A Urabe; K Shirakawa; T Yatomi; N Nakamura; Y Yazaki; H Hirai

  LEUKEMIA & LYMPHOMA, 1999年08月, 査読有り

  
• Early diagnosis of central nervous system aspergillosis using polymerase chain reaction, latex agglutination test, and enzyme-linked immunosorbent assay

  M Kami; S Ogawa; Y Kanda; Y Tanaka; U Machida; T Matsumura; H Sakamaki; H Hirai

  BRITISH JOURNAL OF HAEMATOLOGY, 1999年08月, 査読有り

  
• Frequent false-positive results of Aspergillus latex agglutination test - Transient Aspergillus antigenemia during neutropenia

  M Kami; Y Kanda; S Ogawa; S Mori; Y Tanaka; H Honda; S Chiba; K Mitani; Y Yazaki; H Hirai

  CANCER, 1999年07月, 査読有り

  
• Intramural hematoma of stomach after splenectomy for idiopathic thrombocytopenic purpura [10]

  M. Kami; A. Matsukura; Y. Kanda; S. Ogawa; M. Makuuchi; H. Hirai

  Haematologica, 1999年, 査読有り

  
• TT virus in frequently transfused patients

  Y Kanda; S Chiba; Y Tanaka; M Kami; T Saito; T Asai; K Izutsu; K Yuji; S Ogawa; H Honda; K Mitani; Y Yazaki; H Hirai

  AMERICAN JOURNAL OF MEDICINE, 1999年01月, 査読有り

  
• Early diagnosis of central nervous system aspergillosis with combination use of cerebral diffusion-weighted echo-planar magnetic resonance image and polymerase chain reaction of cerebrospinal fluid

  M Kami; Shirouzu, I; K Mitani; S Ogawa; T Matsumura; Y Kanda; T Masumoto; T Saito; Y Tanaka; K Maki; H Honda; S Chiba; K Ohtomo; H Hirai; Y Yazaki

  INTERNAL MEDICINE, 1999年01月, 査読有り

  
• The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-β-mediated growth inhibition of myeloid cells

  M. Kurokawa; K. Mitani; Y. Imai; S. Ogawa; Y. Yazaki; H. Hirai

  Blood, 1998年12月, 査読有り

  
• TLE, the human homolog of Groucho, interacts with AML1 and acts as a repressor of AML1-induced transactivation

  Y Imai; M Kurokawa; K Tanaka; AD Friedman; S Ogawa; K Mitani; Y Yazaki; H Hirai

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998年11月, 査読有り

  
• Increased soluble Fas-ligand in sera of bone marrow transplant recipients with acute graft-versus-host disease

  Y Kanda; Y Tanaka; K Shirakawa; T Yatomi; N Nakamura; M Kami; T Saito; K Izutsu; T Asai; K Yuji; S Ogawa; H Honda; K Mitani; S Chiba; Y Yazaki; H Hirai

  BONE MARROW TRANSPLANTATION, 1998年10月, 査読有り

  
• Phimosis as a manifestation of chronic graft-versus-host disease after allogeneic bone marrow transplantation

  M Kami; Y Kanda; M Sasaki; N Takeda; Y Tanaka; T Saito; S Ogawa; H Honda; S Chiba; K Mitani; H Hirai; Y Yazaki

  BONE MARROW TRANSPLANTATION, 1998年04月, 査読有り

  
• The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2β(CBFβ) in the nucleus more efficiently than wild-type AML1

  K. Tanaka; T. Tanaka; M. Kurokawa; Y. Imai; S. Ogawa; K. Mitani; Y. Yazaki; H. Hirai

  Blood, 1998年03月, 査読有り

  
• Frameshift mutations of the hMSH6 gene in human leukemia cell lines

  N Hosoya; A Hangaishi; S Ogawa; K Miyagawa; K Mitani; Y Yazaki; H Hirai

  JAPANESE JOURNAL OF CANCER RESEARCH, 1998年01月, 査読有り

  
• The limitation of circulating aspergillus antigen detection methods for BMT recipients [3]

  M. Kami; Y. Tanaka; S. Ogawa; Y. Kanda; H. Honda; S. Chiba; K. Mitani; Y. Yazaki; H. Hirai

  Bone Marrow Transplantation, 1998年, 査読有り

  
• Subcellular localization of the MEN, MLL/MEN and truncated MLL proteins expressed in leukemic cells carrying the t(11;19)(q23;p13.1) translocation

  Y Kanda; K Mitani; T Tanaka; K Tanaka; S Ogawa; Y Yazaki; H Hirai

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 1997年08月, 査読有り

  
• Requirements for localization of p130(cas) to focal adhesions

  T Nakamoto; R Sakai; H Honda; S Ogawa; H Ueno; T Suzuki; S Aizawa; Y Yazaki; H Hirai

  MOLECULAR AND CELLULAR BIOLOGY, 1997年07月, 査読有り

  
• No concomitant occurrence of the N-ras and p53 gene mutations in myelodysplastic syndromes

  K Mitani; A Hangaishi; N Imamura; K Miyagawa; S Ogawa; Y Kanda; Y Yazaki; H Hirai

  LEUKEMIA, 1997年06月, 査読有り

  
• Deletions of p15 and/or p16 genes as a poor-prognosis factor in adult T-cell leukemia

  Y Yamada; Y Hatta; K Murata; K Sugawara; S Ikeda; M Mine; T Maeda; Y Hirakata; S Kamihira; K Tsukasaki; S Ogawa; H Hirai; HP Koeffler; M Tomonaga

  JOURNAL OF CLINICAL ONCOLOGY, 1997年05月, 査読有り

  
• Mutations and loss of expression of a mismatch repair gene, hMLH1, in leukemia and lymphoma cell lines

  A Hangaishi; S Ogawa; K Mitani; N Hosoya; S Chiba; Y Yazaki; H Hirai

  BLOOD, 1997年03月, 査読有り

  
• The correlation between alterations of cell cycle-regulating, tumor-suppressor genes and the clinical prognosis in adult ALL patients

  A. Hangaishi; S. Ogawa

  [Rinshō ketsueki] The Japanese journal of clinical hematology, 1997年, 査読有り

  
• Recent progress in molecular mechanisms of leukemogenesis: The cyclin-dependent kinase 4-inhibitor gene in human leukemias

  Hisamaru Hirai; Seishi Ogawa; Akira Hangaishi; Tokiharu Takahashi; Mineo Kurokawa; Kinuko Mitani; Ryuzo Ueda; Yoshio Yazaki

  Leukemia, 1997年, 査読有り

  
• Structurally altered Evi-1 protein generated in the 3q21q26 syndrome

  S Ogawa; M Kurokawa; T Tanaka; K Mitani; J Inazawa; A Hangaishi; K Tanaka; Y Matsuo; J Minowada; T Tsubota; Y Yazaki; H Hirai

  ONCOGENE, 1996年07月, 査読有り

  
• A conserved cysteine residue in the runt homology domain of AML1 is required for the DNA binding ability and the transforming activity on fibroblasts

  M Kurokawa; T Tanaka; K Tanaka; N Hirano; S Ogawa; K Mitani; Y Yazaki; H Hirai

  JOURNAL OF BIOLOGICAL CHEMISTRY, 1996年07月, 査読有り

  
• Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1/p16(INK4A)/CDKN2, MTS2/p15(INK4B), p53, and Rb genes in primary lymphoid malignancies

  A Hangaishi; S Ogawa; N Imamura; S Miyawaki; Y Miura; N Uike; C Shimazaki; N Emi; K Takeyama; S Hirosawa; N Kamada; Y Kobayashi; Y Takemoto; T Kitani; K Toyama; S Ohtake; Y Yazaki; R Ueda; H Hirai

  BLOOD, 1996年06月, 査読有り

  
• Increased Evi-1 expression is frequently observed in blastic crisis of chronic myelocytic leukemia

  S Ogawa; M Kurokawa; T Tanaka; K Tanaka; A Hangaishi; K Mitani; N Kamada; Y Yazaki; H Hirai

  LEUKEMIA, 1996年05月, 査読有り

  
• Overexpression of the AML1 proto-oncoprotein in NIH3T3 cells leads to neoplastic transformation depending on the DNA-binding and transactivational potencies

  M Kurokawa; T Tanaka; K Tanaka; S Ogawa; K Mitani; Y Yazaki; H Hirai

  ONCOGENE, 1996年02月, 査読有り

  
• Abnormal expression of Evi-1 gene in human leukemias.

  S. Ogawa; K. Mitani; M. Kurokawa; Y. Matsuo; J. Minowada; J. Inazawa; N. Kamada; T. Tsubota; Y. Yazaki; H. Hirai

  Human cell : official journal of Human Cell Research Society, 1996年, 査読有り

  
• TPO/C-MPL LIGAND INDUCES TYROSINE PHOSPHORYLATION OF MULTIPLE CELLULAR PROTEINS INCLUDING PROTOONCOGENE PRODUCTS, VAV AND C-CBL, AND RAS SIGNALING MOLECULES

  K SASAKI; H ODAI; Y HANAZONO; H UENO; S OGAWA; WY LANGDON; T TANAKA; K MIYAGAWA; K MITANI; Y YAZAKI; H HIRAI

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1995年11月, 査読有り

  
• THE AML1 EVI-1 FUSION PROTEIN IN THE T(3-21) TRANSLOCATION EXHIBITS TRANSFORMING ACTIVITY ON RAT1 FIBROBLASTS WITH DEPENDENCE ON THE EVI-1 SEQUENCE

  M KUROKAWA; S OGAWA; T TANAKA; K MITANI; Y YAZAKI; ON WITTE; H HIRAI

  ONCOGENE, 1995年09月, 査読有り

  
• LOSS OF THE CYCLIN-DEPENDENT KINASE 4-INHIBITOR (P16-MTS1) GENE IS FREQUENT IN AND HIGHLY SPECIFIC TO LYMPHOID TUMORS IN PRIMARY HUMAN HEMATOPOIETIC MALIGNANCIES

  S OGAWA; A HANGAISHI; S MIYAWAKI; S HIROSAWA; Y MIURA; K TAKEYAMA; N KAMADA; S OHTAKE; N UIKE; C SHIMAZAKI; K TOYAMA; M HIRANO; H MIZOGUCHI; Y KOBAYASHI; S FURUSAWA; M SAITO; N EMI; Y YAZAKI; R UEDA; H HIRAI

  BLOOD, 1995年08月, 査読有り

  
• GROWTH-INHIBITION OF LEUKEMIC-CELLS CARRYING THE T(3-21) BY THE AML1/EVI-1-SPECIFIC ANTISENSE OLIGONUCLEOTIDE

  K MITANI; S OGAWA; T TANAKA; M KUROKAWA; Y YAZAKI; H HIRAI

  BRITISH JOURNAL OF HAEMATOLOGY, 1995年07月, 査読有り

  
• INCREASED EXPRESSION OF AML1 DURING RETINOIC-ACID-INDUCED DIFFERENTIATION OF U937 CELLS

  K TANAKA; T TANAKA; S OGAWA; M KUROKAWA; K MITANI; Y YAZAKI; H HIRAI

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1995年06月, 査読有り

  
• DUAL FUNCTIONS OF THE AML1/EVI-1 CHIMERIC PROTEIN IN THE MECHANISM OF LEUKEMOGENESIS IN T(3-21) LEUKEMIAS

  T TANAKA; K MITANI; M KUROKAWA; S OGAWA; K TANAKA; J NISHIDA; Y YAZAKI; Y SHIBATA; H HIRAI

  MOLECULAR AND CELLULAR BIOLOGY, 1995年05月, 査読有り

  
• CLONING OF SEVERAL SPECIES OF MLL/MEN CHIMERIC CDNAS IN MYELOID-LEUKEMIA WITH T(11-19)(Q23-P13.1) TRANSLOCATION

  K MITANI; Y KANDA; S OGAWA; T TANAKA; J INAZAWA; Y YAZAKI; H HIRAI

  BLOOD, 1995年04月, 査読有り

  
• FREQUENT LOSS OF THE CYCLIN-DEPENDENT KINASE-4 INHIBITOR GENE IN HUMAN GLIOMAS

  A GOMI; R SAKAI; S OGAWA; S SHINODA; H HIRAI; T MASUZAWA

  JAPANESE JOURNAL OF CANCER RESEARCH, 1995年04月, 査読有り

  
• An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms

  T. Tanaka; K. Tanaka; S. Ogawa; M. Kurokawa; K. Mitani; J. Nishida; Y. Shibata; Y. Yazaki; H. Hirai

  EMBO Journal, 1995年, 査読有り

  
• CHARACTERIZATION, PARTIAL-PURIFICATION, AND PEPTIDE SEQUENCING OF P130, THE MAIN PHOSPHOPROTEIN ASSOCIATED WITH V-CRK ONCOPROTEIN

  R SAKAI; A IWAMATSU; N HIRANO; S OGAWA; T TANAKA; J NISHIDA; Y YAZAKI; H HIRAI

  JOURNAL OF BIOLOGICAL CHEMISTRY, 1994年12月, 査読有り

  
• MOLECULAR ANALYSIS OF THE T(1-19)(Q23-P13)-TRANSLOCATION OBSERVED IN ADULT LEUKEMIAS

  K MITANI; K SASAKI; S OGAWA; Y HAYASHI; H MANO; Y YAZAKI; H HIRAI

  INTERNATIONAL JOURNAL OF HEMATOLOGY, 1994年12月, 査読有り

  
• HOMOZYGOUS LOSS OF THE CYCLIN-DEPENDENT KINASE 4-INHIBITOR (P16) GENE IN HUMAN LEUKEMIAS

  S OGAWA; N HIRANO; N SATO; T TAKAHASHI; A HANGAISHI; K TANAKA; M KUROKAWA; T TANAKA; K MITANI; Y YAZAKI; H HIRAI

  BLOOD, 1994年10月, 査読有り

  
• A NOVEL SIGNALING MOLECULE, P130, FORMS STABLE COMPLEXES IN-VIVO WITH V-CRK AND V-SRC IN A TYROSINE PHOSPHORYLATION-DEPENDENT MANNER

  R SAKAI; A IWAMATSU; N HIRANO; S OGAWA; T TANAKA; H MANO; Y YAZAKI; H HIRAI

  EMBO JOURNAL, 1994年08月, 査読有り

  
• THE C-TERMINAL SH3 DOMAIN OF THE MOUSE C-CRK PROTEIN NEGATIVELY REGULATES TYROSINE-PHOSPHORYLATION OF CRK ASSOCIATED P130 IN RAT 3Y1 CELLS

  S OGAWA; H TOYOSHIMA; H KOZUTSUMI; K HAGIWARA; R SAKAI; T TANAKA; N HIRANO; H MANO; Y YAZAKI; H HIRAI

  ONCOGENE, 1994年06月, 査読有り

  
• GENERATION OF THE AML1-EVI-1 FUSION GENE IN THE T(3 21)(Q26 Q22) CAUSES BLASTIC CRISIS IN CHRONIC MYELOCYTIC-LEUKEMIA

  K MITANI; S OGAWA; T TANAKA; H MIYOSHI; M KUROKAWA; H MANO; Y YAZAKI; M OHKI; H HIRAI

  EMBO JOURNAL, 1994年02月, 査読有り

  
• Evi-1 raises AP-1 activity and stimulates c-fos promoter transactivation with dependence on the second zinc finger domain

  T. Tanaka; J. Nishida; K. Mitani; S. Ogawa; Y. Yazaki; H. Hirai

  Journal of Biological Chemistry, 1994年, 査読有り

  
• Hemophagocytic syndrome associated with non-Hodgkin\\'s lymphoma of B-cell type [7]

  T. Nakamoto; S. Ogawa; H. Mano; H. Hirai; Y. Yazaki

  American Journal of Hematology, 1994年, 査読有り

  
• Rearrangement of retinoic acid receptor α and PML in promyelocytic blast crisis of Ph¹ chromosome positive chronic myelocytic leukemia with normal copies of chromosome 15 [4]

  M. Amano; A. Togawa; S. Tsurugano; Y. Soda; A. Yuo; F. Takaku; S. Ogawa; H. Hirai; K. Yamada

  Blood, 1993年05月, 査読有り

  
• Detection of the PML/RARα fusion gene in acute promyelocytic leukemia with a complex translocation involving chromosomes 15, 17, and 18

  S. Ogawa; K. Mitani; Y. Sato; K. Sugimoto; H. Toyoshima; H. Mano; F. Takaku; Y. Yazaki; H. Hirai

  Cancer Genetics and Cytogenetics, 1993年, 査読有り

  

MISC

• Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray

  Norihiko Kawamata; Seishi Ogawa; Martin Zimmermann; Birte Niebuhr; Carol Stocking; Masashi Sanadad; Kari Hemminki; Go Yamatomo; Yasuhito Nannya; Rolf Koehler; Thomas Flohr; Carl W. Miller; Jochen Harbott; Wolf-Dieter Ludwig; Martin Stanulla; Martin Schrappe; Claus R. Bartram; H. Phillip Koeffler

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008年08月, 査読有り

  
• Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate

  Mamiko Sakata-Yanagimoto; Etsuko Nakagami-Yamaguchi; Toshiki Saito; Keiki Kumano; Koji Yasutomo; Seishi Ogawa; Mineo Kurokawa; Shigeru Chiba

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008年06月, 査読有り

  

外部資金：科学研究費補助金

• 新規単一細胞解析技術を用いた、段階的・階層的な変異獲得によるがん発症過程の解明

  挑戦的研究(萌芽)

  中区分50:腫瘍学およびその関連分野

  京都大学

  小川 誠司

  自 2020年07月30日, 至 2022年03月31日, 完了

  単一細胞シーケンス;遺伝子変異;クローン進化;白血病

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20K21546/
• 食道がん化における初期のゲノム異常の解明-多発ヨード不染の網羅的ゲノム解析-

  基盤研究(B)

  小区分53010:消化器内科学関連

  京都大学

  横山 顕礼

  自 2020年04月01日, 至 2023年03月31日, 完了

  食道がん;飲酒;喫煙;ヨード不染;がんの起源;食道扁平上皮がん;上皮内腫瘍;ヨード不染色;網羅的ゲノム解析;食道扁平上皮;ゲノム解析;老化;食道扁平上皮癌;リスク因子

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H03660/
• 先端ゲノミクスを駆使したがんの初期発生とクローン進化に関わる分子基盤の解明

  基盤研究(S)

  大区分I

  京都大学

  小川 誠司

  自 2019年06月26日, 至 2024年03月31日, 交付

  ゲノム生物学;腫瘍学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19H05656/
• 複数回の造血幹細胞移植後にもかかわらず再発した白血病細胞の免疫回避機構の解明

  基盤研究(C)

  小区分54010:血液および腫瘍内科学関連

  兵庫医科大学

  池亀 和博

  自 2018年04月01日, 至 2021年03月31日, 完了

  HLA不適合造血幹細胞移植;白血病;再発;GVHD;HLA;不適合移植;HLA不適合移植;HLA-LOH

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K08376/
• 変異情報付きハイスループットシングルセルRNA-seqによる白血病のクローン解析

  挑戦的研究(萌芽)

  京都大学

  小川 誠司

  自 2017年06月30日, 至 2019年03月31日, 完了

  骨髄異形成症候群;白血病;クローン進展;単一細胞解析;腫瘍内多様性

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K19595/
• 新規DDX41遺伝子変異による骨髄系腫瘍の発症メカニズムの解明

  若手研究(B)

  京都大学

  昆 彩奈

  自 2016年04月01日, 至 2018年03月31日, 完了

  骨髄異形成症候群;急性骨髄性白血病;遺伝子改変マウス;新規遺伝子変異;DDX41;マウスモデル;遺伝子変異

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K19574/
• 大腸癌の発生基盤の解明

  挑戦的萌芽研究

  京都大学

  小川 誠司

  自 2016年04月01日, 至 2017年03月31日, 完了

  大腸癌;遺伝子変異;発がん;大腸

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K14607/
• スーパーエンハンサーによる脳腫瘍の発生と悪性化のクロマチンダイナミクスの解明

  基盤研究(B)

  名古屋大学

  夏目 敦至

  自 2016年04月01日, 至 2019年03月31日, 完了

  脳腫瘍;エピゲノム;ヒストン;EZH2;ポリコーム;ゲノム;脳腫瘍学;創薬;癌;ゲノム構造;スーパーエンハンサー

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16H05436/
• 再生不良性貧血におけるクローン性造血の起源の探求

  挑戦的萌芽研究

  京都大学

  小川 誠司

  自 2015年04月01日, 至 2016年03月31日, 完了

  血液内科学;血液免疫学;再生不良性貧血;体細胞変異;細胞障害性T細胞;クローン性造血

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K15361/
• 大規模シーケンスとコンピューティングによるがんの進化と多様性の解明

  新学術領域研究(研究領域提案型)

  複合領域

  京都大学

  小川 誠司

  自 2015年06月29日, 至 2020年03月31日, 完了

  RNAシーケンス;総合生物;ゲノム科学;システムゲノム科学;腫瘍学;DNAシーケンス

  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-15H05909/
• 領域の研究方針の策定

  新学術領域研究(研究領域提案型)

  複合領域

  東京大学

  宮野 悟

  自 2015年06月29日, 至 2020年03月31日, 完了

  がん;システム生物学;統計的モデリング;バイオインフォマティクス;人工知能;ゲノム科学

  https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-15H05907/
• 異種移植モデルを用いたダウン症候群関連白血病の病態解析および特異的治療の基盤開発

  若手研究(B)

  京都大学

  才田 聡

  自 2014年04月01日, 至 2016年03月31日, 完了

  白血病;ダウン症候群;一過性異常骨髄増殖症;急性巨核芽球性白血病;TAM;AMKL;NOGマウス;異種移植

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26860795/
• 小児難治性白血病を対象としたDNA・RNAの包括的構造解析

  若手研究(A)

  国立研究開発法人国立成育医療研究センター;東京大学

  加藤 元博

  自 2014年04月01日, 至 2017年03月31日, 完了

  癌;小児白血病;分子遺伝学;ゲノム解析

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26713037/
• 急性骨髄性白血病におけるクローン進化の空間的多様性の検討

  挑戦的萌芽研究

  京都大学

  小川 誠司

  自 2014年04月01日, 至 2015年03月31日, 完了

  急性骨髄白血病;腫瘍内多様性;全エクソンシーケンス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26670466/
• ダウン症関連急性巨核芽球性白血病の発がんメカニズムの解明

  基盤研究(C)

  名古屋大学

  濱 麻人

  自 2014年04月01日, 至 2017年03月31日, 完了

  ダウン症;一過性異常骨髄増殖症;急性巨核芽球性白血病;GATA1;コヒーシン;CTCF;次世代シークエンサー;ターゲットシークエンス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26461579/
• RNAスプライシング変異によるMDS発症の分子メカニズムの解明

  基盤研究(A)

  京都大学

  小川 誠司

  自 2014年04月01日, 至 2015年03月31日, 中途終了

  骨髄異形成症候群;全エクソンシーケンス;RNAスプライシング因子

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26253060/
• 骨髄異形成症候群(MDS)の分子基盤の解明

  基盤研究(S)

  京都大学

  小川 誠司

  自 2014年05月30日, 至 2019年03月31日, 完了

  血液内科学;血液腫瘍学;骨髄異形成症候群;二次性白血病;スプライシング因子;コヘシン;クローン進化;マウスモデル;ゲノムシーケンス;遺伝子変異

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26221308/
• シグナルパスウェイ構成蛋白の発現・変異解析による造血抑制性サイトカインの同定

  挑戦的萌芽研究

  金沢大学

  中尾 眞二

  自 2013年04月01日, 至 2015年03月31日, 完了

  再生不良性貧血;造血抑制性サイトカイン;インターロイキン１０;CXCL12;クローン性造血;マイクロアレイ;発作性夜間血色素尿症;ゲノム変異;NFAT;Nr4a;シクロスポリン;エクソームシーケンシング

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25670448/
• 骨髄異形成症候群における自己免疫機序の解明

  挑戦的萌芽研究

  東京大学

  小川 誠司

  自 2013年04月01日, 至 2014年03月31日, 完了

  骨髄異形成症候群;自己免疫;HLAテトラマー

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25670446/
• 前立腺癌における一塩基多型の意義－５５箇所の多型分析と臨床所見・予後との関連－

  基盤研究(C)

  東京大学

  鈴木 基文

  自 2012年04月01日, 至 2015年03月31日, 完了

  前立腺癌;遺伝子解析;一塩基多型

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24592378/
• 造血器腫瘍におけるＴＥＴ２遺伝子異常とエピジェネティック制御の解析

  基盤研究(B)

  筑波大学

  千葉 滋

  自 2012年04月01日, 至 2015年03月31日, 完了

  TET2;T細胞リンパ腫;エピゲノム;T細胞;リンパ腫;エピジェネティック制御;エピジェネティック;造血器腫瘍;シトシン;メチル化

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24390241/
• ハプロ一致移植後再発ＨＬＡ－ＬＯＨ白血病細胞におけるＮＫ細胞傷害メカニズムの解明

  基盤研究(C)

  名古屋大学

  高橋 義行

  自 2011年04月01日, 至 2014年03月31日, 完了

  白血病;NK細胞;GVL効果;KIR;造血幹細胞移植;HLA

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23591536/
• 白血病幹細胞の維持と再発・治療抵抗性に関わる遺伝学的基盤の解明

  基盤研究(A)

  京都大学;東京大学

  小川 誠司

  自 2011年04月01日, 至 2014年03月31日, 完了

  白血病;幹細胞;リシーケンス;遺伝子変異;エピゲノム;高速シーケンス;再発;難治性白血病;ゲノム;エクソーム解析;エピゲノム解析;大量並列シーケンス;RNAスプライシング;治療抵抗性;全ゲノム解析

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23249052/
• スニップマイクロアレイおよび幹細胞に基づく悪性神経膠腫の新規治療法の開発

  基盤研究(C)

  熊本大学

  中村 英夫

  自 2010年04月01日, 至 2013年03月31日, 完了

  脳腫瘍学;スニップマイクロアレイ;薬剤耐性;グリオーマ幹細胞;GSC移植動物モデル;薬剤耐性に関する遺伝子;遺伝子プロファイリング;テモダール耐性;グリオーマ幹細胞(GSC);幹細胞培養;悪性グリオーマ;抗がん剤耐性株

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22591616/
• 大規模ゲノムシーケンスに基づく癌の個性の理解と分子標的の探索

  新学術領域研究(研究領域提案型)

  複合領域

  京都大学;東京大学

  小川 誠司

  自 2010年04月01日, 至 2015年03月31日, 完了

  がんゲノム;SNPアレイ;リシーケンス;癌の個性;分子標的;白血病;造血幹細胞;造血器腫瘍;大量並列シーケンス;腫瘍内多様性;成人T細胞白血病;血管免疫芽球性T細胞リンパ種;RHOA変異;Low grade glioma;ゲノム;エクソンシーケンス;がん;RNAスプライシング;ATL;miR31;MDS;SF3B1;クロマチン制御;腎細胞癌

  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-22134006/
• 領域の研究方針の策定

  新学術領域研究(研究領域提案型)

  複合領域

  東京大学

  宮野 悟

  自 2010年04月01日, 至 2015年03月31日, 完了

  がん;システム生物学;ゲノム科学;バイオインフォマティクス;遺伝統計学;腫瘍学

  https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-22134001/
• ダウン症候群におけるTAMの遺伝学的病態解明

  挑戦的萌芽研究

  東京大学

  小川 誠司

  自 2009年04月01日, 至 2010年03月31日, 完了

  TAM;ダウン症候群;SNPアレイ;21トリソミー;GATA1変異;胎生造血;インプリンティング

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21659235/
• マイナー抗原等に関与する責任SNPの新規同定法の開発とネットツールの公開

  基盤研究(C)

  愛知県がんセンター(研究所)

  赤塚 美樹

  自 2009年04月01日, 至 2012年03月31日, 完了

  同種造血細胞移植;白血病;腫瘍免疫;遺伝子多型;国際HapMapプロジェクト;オンラインソフトウエア;バイオテクノロジー;免疫学;SNP;HapMap;パイオテクノロジー

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21591256/
• 網羅的ゲノム・エピゲノム解析による小児固形腫瘍の分子機構解析と分子標的療法の開発

  基盤研究(B)

  群馬県衛生環境研究所

  林 泰秀

  自 2009年04月01日, 至 2012年03月31日, 完了

  小児腫瘍学;遺伝子;ゲノム;マイクロアレイ;癌;臨床

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21390316/
• 先端ゲノミクスによる造血器腫瘍の治療・診断標的分子の同定

  基盤研究(B)

  東京大学

  小川 誠司

  自 2009年04月01日, 至 2012年03月31日, 完了

  ゲノミクス;分子標的;造血器腫瘍;遺伝子診断;ゲノム異常;SNPアレイ;リシーケンス;MDS;ゲノム解析;遺伝子変異;ATL;HTLV-1;CD2;CD28;BCL11B

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20390266/
• 造血系の制御機構の解析とゲノム異常の網羅的探索による造血器腫瘍発症機構の解明

  特定領域研究

  生物系

  東京大学

  小川 誠司

  自 2008年04月01日, 至 2010年03月31日, 完了

  SNPアレイ;悪性リンパ腫;ホジキンリンパ腫;A20;11qUPD;6q23;癌抑制遺伝子;ゲノム解析;MDS;CMML;c-Cb1;チロシンキナーゼ;UPD;造血器腫瘍;ゲノム;マイクロアレイ;ゲノムコピー数異常;高密度オリゴヌクレオチドアレイ;LOH;アレル不均衡;CNAG;Blimp1;造血システム

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17013022/
• 造血器腫瘍の遺伝学的基盤等に関する網羅的ゲノム研究

  基盤研究(B)

  東京大学

  小川 誠司

  自 2006年04月01日, 至 2008年03月31日, 完了

  癌;遺伝学;アレル不均衡;マイクロアレイ;白血病, CANCER;GENETICS;ALLELIC IMBALANCES;MICROARRAY;LEUKEMIA

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18390279/
• DNAアレイを用いた造血細胞分化におけるメチル化プロファイルの網羅的経時的検討

  萌芽研究

  東京大学

  小川 誠司

  自 2004年04月01日, 至 2006年03月31日, 完了

  マイクロアレイ;メチル化;造血幹細胞;分化;コピー数解析;モデルマウス;Affymetrix

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16659250/
• Blimp-1の機能解析

  基盤研究(C)

  東京大学

  半下石 明

  自 2004年04月01日, 至 2006年03月31日, 完了

  Blimp-1;細胞周期;ノックアウトマウス, Blimp-1;cell cycle

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16590924/
• ゲノム解析技術とマウスジェネティクスを駆使した白血病の発症メカニズムの探究

  基盤研究(B)

  東京大学

  小川 誠司

  自 2004年04月01日, 至 2006年03月31日, 完了

  白血病;コピー数解析;SNPアレイ;CNAG;アレル特異的解析;UPD;LOH;マイクロアレイ;Blimp1;細胞周期;モデルマウス;Affymetrix, Leukemia;Copy number analysis;SNP array;CNAG;Allele-specific analysis;UPD;LOH

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16390272/
• ゲノムアレイCGHを用いた造血器腫瘍における染色体欠失・増幅領域の網羅的解析

  特定領域研究

  生物系

  東京大学

  小川 誠司

  自 2003年04月01日, 至 2004年03月31日, 完了

  アレイCGH;造血器腫瘍;染色体;ゲノム;欠損;増幅

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15012212/
• 幹細胞可塑性の分子メカニズムと再生医学研究

  萌芽研究

  東京大学

  千葉 滋;平井 久丸

  自 2002年04月01日, 至 2004年03月31日, 完了

  造血幹細胞;可塑性;ヒトES細胞;血球細胞;Tie2;GFP;再生医療;幹細胞;再生医学;Notch;paraaortic-splanchnopleura(P-SP)領域;血管内皮細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14657241/
• 骨髄異形成症候群におけるt(1;7)転座およびdel(7q)のゲノム解析

  基盤研究(C)

  東京大学

  小川 誠司

  自 2002年04月01日, 至 2004年03月31日, 完了

  t(1;7)(q10;p10);del(7q);メチル化解析;骨髄異形成症候群;アルフォイド配列;CpGアイルランド;メチル化パターン;MDS;CpGアイランド;der(1;7)(q10;p10);欠失解析, t(1;7)(q10:910);del(7q);methylation analysis;myelodysplastic syndrome;alphoid sequences;CpG islands;Methylation pattern;MDS

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14570962/
• 新規転写因子CIZのノックアウトマウスの表現形の解析

  基盤研究(C)

  東京大学

  半下石 明

  自 2002年04月01日, 至 2004年03月31日, 完了

  CIZ;ノックアウトマウス;アポトーシス;生殖細胞;BMP, CIZ;knockout mouse;apoptosis;spermatogenic cell;BMP

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14570179/
• Notchシグナル分子を標的とした免疫調節機構の研究

  基盤研究(B)

  東京大学

  千葉 滋

  自 2002年04月01日, 至 2005年03月31日, 完了

  Notch;同種造血幹細胞移植;移植片対宿主病;トランスジェニックマウス;MHC class IIプロモーター;Jagged1;コンディショナルノックアウト;自然免疫;シランスジェニックマウス;Notchシグナル;造血幹細胞;免疫調節;GVHD;T細胞;コンディショナルノックアウトマウス, Notch;allogeneic hematopoietic stem cell transplantation;graft-versus-host disease;transgenic mouse;MHC class II promoter;Jagged1;conditional knockout mouse;innate immunity

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14370300/
• ヒト染色体6qに存在する癌抑制遺伝子群の同定

  特定領域研究

  生物系

  東京大学

  小川 誠司

  自 2002年04月01日, 至 2003年03月31日, 完了

  リンパ系腫瘍;6q;アレイCGH;BAC;Blimp1;メチル化

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14026011/
• 造血器腫瘍における染色体欠失領域の網羅的解析

  特定領域研究

  生物系

  東京大学

  小川 誠司

  自 2002年04月01日, 至 2003年03月31日, 完了

  造血器腫瘍;染色体欠失;アレイCGH;BAC;6q

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14013018/
• 造血器腫瘍に対する腫瘍免疫療法の開発と実用化

  基盤研究(B)

  東京大学

  千葉 滋;平井 久丸

  自 2001年04月01日, 至 2004年03月31日, 完了

  NKT細胞;Vα24;CD8+;α-galactosyl ceramide;CD1d;Tリンパ芽球性白血病;リンパ腫;IFN-γ;IL-4;IL-10;Th1;Th2バランス;CDld;慢性骨髄性白血病;免疫細胞療法;樹状細胞;bcr;bal;抹消血樹状細胞;探求由来樹状細胞;共刺激分子;HLA分子, NKT cell;Vα24;CD8+;α-galactosy ceramide;CD1d;T lymphoblastic leukemia

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13557080/
• ヒト6番染色体に存在する新規癌抑制遺伝子の同定と単離

  特定領域研究(C)

  生物系

  東京大学

  小川 誠司

  自 2001年04月01日, 至 2003年03月31日, 完了

  6番染色体長腕;悪性リンパ腫;FISH;癌抑制遺伝子;ホモ接合性欠失;GIRK2遺伝子;Blimp-1遺伝子;造血器腫瘍

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13214026/
• Notchリガンドを利用した造血幹細胞の増幅とその実用化

  萌芽的研究

  東京大学

  平井 久丸

  自 2000年04月01日, 至 2002年03月31日, 完了

  Notch;造血幹細;造血発生;1次造血;2次造血;HES-1;paraaortic splanchnopleures;yalk sac;Notchシグナル;Notchリガンド;GATA-2;造血幹細胞;ES細胞;造血幹細胞増幅;活性化型Notch1;RAS;MAPKシグナル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12877156/
• t(1;7)(q10,p10)転座を有する骨髄異形成症候群の病態解明

  基盤研究(C)

  東京大学

  小川 誠司

  自 2000年04月01日, 至 2002年03月31日, 完了

  t(1;7)転座;骨髄異形成症候群;切断点;アルフォイド配列;セントロメア;FISH;1番染色体;7番染色体;二次性白血病;alphoid反復配列;二動原体染色体, t(l ; 7) (q10 ; p10);myelodysplastic syndrome;breakpoint;alphoid sequence;centromere;FISH;chromosome 1;chromosome 7

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12670974/
• シグナル伝達機構に基づく細胞の分化と死の制御機構

  特定領域研究

  生物系

  東京大学;東京医科歯科大学

  一條 秀憲

  自 2000年04月01日, 至 2005年03月31日, 完了

  ASK1;ASKファミリー;MAPキナーゼ;アポトーシス;Blimp1;ストレス;ASK2;Nef;c-Myc;TAK1

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12215037/
• 東海村臨界事故における中性子線被爆による染色体・遺伝子異常の解析

  特定領域研究(C)

  生物系

  東京大学

  小川 誠司

  自 2000年04月01日, 至 2001年03月31日, 完了

  東海村;臨界事故;放射線被曝;中性子線;染色体異常;遺伝子変異;造血幹細胞移植

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12213031/
• 新則シグナル伝達分子Casの多角的機能解析

  基盤研究(A)

  東京大学

  平井 久丸

  自 1999年04月01日, 至 2001年03月31日, 完了

  Cas;CIZ;細胞接着;細胞骨格;マトリックス・メタロプロテアーゼ;アクチン;心筋線維;インテグリン;SH3;マトリックスメタロプロテアーゼ;プロモーター;転写制御, Cas;CIZ;focal adhesion;SH3 domain;matrix metalloproteinase;actin stress fiber;nucleo-cytoplasmic shuttling protein

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11694250/
• Notchシグナルによる造血の制御

  基盤研究(C)

  東京大学

  千葉 滋

  自 1999年04月01日, 至 2001年03月31日, 完了

  Notch;シグナル;分子内切断;リン酸化;造血;分子抑制;GATA2;Notchリガンド;DSL蛋白質;分化抑制, Notch;signal;cleavage;phosphorylation;hematopoiesis;differentiation inhibition;GATA2

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11670980/
• キメラ型転写因子による白血病発症の分子機構の解析

  基盤研究(B)

  獨協医科大学;東京大学

  三谷 絹子

  自 1999年04月01日, 至 2002年03月31日, 完了

  AML1;EVI-1;TGFβ;CtBP;Smad3;JNK;アポトーシス;MLL;MEN;p53;MEM;転写伸長因子;ノックアウトマウス;t(11;19);白血病;キメラ型転写因子;t(3;21);Evi-1, AML1;EVI-1;TGFβ;CtBP;Smad3;JNK;apoptosis;MLL;MEN;p53

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11470208/
• ヒト染色体6q16.3-21に存在する新規癌抑制遺伝子の同定と単離

  特定領域研究(A)

  東京大学

  小川 誠司

  自 1999年04月01日, 至 2000年03月31日, 完了

  6q21;急性リンパ性白血病;癌抑制遺伝子;FISH;欠失;非ホジキンリンパ腫

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11149205/
• 造血幹細胞複製因子の同定・単離とその実用化

  萌芽的研究

  東京大学

  平井 久丸

  自 1998年04月01日, 至 2000年03月31日, 完了

  造血幹細胞;Notch;骨髄系前駆細胞;赤芽球系細胞;転写因子;GATA-2;分化;幹細胞増幅;骨髄支持細胞;Notchl;赤芽球系前駆細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10877155/
• 発生工学的手法を用いたヒト白血病モデルマウスの作製

  萌芽的研究

  東京大学

  三谷 絹子

  自 1998年04月01日, 至 2000年03月31日, 完了

  転写因子;白血病;RNAポリメラーゼII伸長因子;MEN;MLL;t(11;19);ノックアウト;ノックイン

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10877154/
• 急性リンパ性白血病における染色体6q21-23領域の欠失の解析

  奨励研究(A)

  東京大学

  小川 誠司

  自 1998年04月01日, 至 2000年03月31日, 完了

  6q21;急性リンパ性白血病;癌抑制遺伝子;FISH;欠失;非ホジキンリンパ腫;6q14-23;FISH法;悪性リンパ腫;欠失マッピング;ホモ接合性欠失

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10770503/
• ノックアウトマウスを用いた新規情報伝達物質p130^の生物学的機能解析

  特定領域研究(A)

  東京大学

  小川 誠司

  自 1998年04月01日, 至 1999年03月31日, 完了

  p130^;ノックアウトマウス;actin線維の束状形成;c-Crk;c-Src;血管拡張;FAK;チロシンリン酸化

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10152214/
• アデノウィルスベクターを用いた新しい造血幹細胞体外増幅法の開発

  基盤研究(C)

  東京大学

  千葉 滋

  自 1997年04月01日, 至 1999年03月31日, 完了

  CD34陽性細胞;上皮細胞増殖因子;コロニー;アデノウイルス;LTC-IC;未熟造血細胞;体外増幅;上皮細胞増殖因子(EGF);EGF受容体、組み換えアデノウイルス;血液前駆細胞の体外増幅;インターロイキン6(IL-6);SCF, ex vivo expansion;hematopoietic stem cell;adenovirus vector;epidermal growth factor;CD34+cells;long-term culture-initiating cell;colony-forming unit

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09671091/
• 新しい造血幹細胞体外増幅法の開発と実用化

  基盤研究(A)

  東京大学

  平井 久丸

  自 1997年04月01日, 至 2000年03月31日, 完了

  Notch蛋白質;DSLドメイン;Jagged1;細胞分化;活性化型Notch1;転写因子;GATA-2;Notch1;Notch2;Notch3;EGF様リピート;造血幹細胞;自己複製能;ストローマ細胞;ES細胞;遺伝子治療;CD34;アデノウイルス;EGF受容体;LTC-IC, Notch;DSL domain;Jagged1;differentiation;active Notch1;transcription factor;GATA-2

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09357010/
• 白血病発症の分子機構の解析

  基盤研究(A)

  東京大学

  平井 久丸

  自 1997年04月01日, 至 2000年03月31日, 完了

  白血病;Evi-1;TGFβ;smad3;増殖抑制;JNK;ストレス刺激;アポトーシス;核内蛋白質;zinc finger;MAP kinase;転写因子;増殖抑制因子;Smad3;t(11;19)転座型白血病;MLL遺伝子;MEN遺伝子;MLL;転写伸長因子;足場非依存性増殖, Leukemia;Evi-1;TGFβ;Smad3;Cell growth;JNK;Stress;Apoptosis

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09307021/
• 基本転写因子異常による造血幹細胞腫瘍化の機構の解析

  重点領域研究

  東京大学

  三谷 絹子

  自 1997年04月01日, 至 1998年03月31日, 完了

  RNAポリメラーゼII伸長因子;MEN;t(11;19);白血病;AP‐1活性;転写伸長因子

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09250204/
• 前白血病状態進展にかかわる転写因子異常の解析

  基盤研究(C)

  東京大学

  三谷 絹子

  自 1996年04月01日, 至 1998年03月31日, 完了

  RNAポリメラーゼII伸長因子;転写伸長因子;MEN;t(11;19);白血病;AP-1活性;骨髄異形成症候群;t(11;19)(q.23;P13.1);MLL;転写因子;伸長因子, RNA polymerase II elongation factor;elongation factor;MEN;t(11 ; 19);leukemia;AP-1 activity

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08671215/
• 加齢や慢性ストレスにより変容する副腎組織の分子基盤と破綻病態の統合的理解

  基盤研究(S)

  大区分I

  九州大学

  小川 佳宏

  自 2022年04月27日, 至 2027年03月31日, 交付

  副腎;副腎腫瘍;ステロイドミクス;統合オミクス解析;機械学習

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22H04993/
• がんと正常組織におけるクローン進化の解明

  特別推進研究

  生物系

  京都大学

  小川 誠司

  自 2024年04月01日, 至 2028年03月31日, 交付

  がん;体細胞モザイク;クローン進化;加齢;ゲノム・エピゲノム解析

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24H00009/

教育

担当科目

• 自 2024年04月01日, 至 2025年03月31日

  腫瘍学（実習）

  P008, 通年不定, 医学研究科, 2
• 自 2024年04月01日, 至 2025年03月31日

  腫瘍学（修士実習）

  E041, 通年不定, 医学研究科, 2
• 自 2024年04月01日, 至 2025年03月31日

  B9 病理学総論

  B014, 前期, 医学部, 2.5
• 自 2024年04月01日, 至 2025年03月31日

  腫瘍学（演習）

  P007, 通年不定, 医学研究科, 4
• 自 2024年04月01日, 至 2025年03月31日

  腫瘍学（修士演習）

  E040, 通年不定, 医学研究科, 4
• 自 2024年04月01日, 至 2025年03月31日

  病理学　II

  E012, 前期不定, 医学研究科, 4
• 自 2024年04月01日, 至 2025年03月31日

  腫瘍免疫学特論

  8211, 通年不定, 薬学研究科, 2
• 自 2023年04月01日, 至 2024年03月31日

  腫瘍学（実習）

  P008, 通年不定, 医学研究科, 2
• 自 2023年04月01日, 至 2024年03月31日

  腫瘍学（修士実習）

  E041, 通年不定, 医学研究科, 2
• 自 2023年04月01日, 至 2024年03月31日

  腫瘍学（演習）

  P007, 通年不定, 医学研究科, 4
• 自 2023年04月01日, 至 2024年03月31日

  腫瘍学（修士演習）

  E040, 通年不定, 医学研究科, 4
• 自 2023年04月01日, 至 2024年03月31日

  腫瘍免疫学特論

  8211, 通年不定, 薬学研究科, 2
• 自 2022年04月01日, 至 2023年03月31日

  腫瘍学（修士実習）

  E041, 通年不定, 医学研究科, 2
• 自 2022年04月01日, 至 2023年03月31日

  腫瘍学（修士演習）

  E040, 通年不定, 医学研究科, 4
• 自 2022年04月01日, 至 2023年03月31日

  腫瘍免疫学特論

  8211, 通年不定, 薬学研究科, 2
• 自 2022年04月01日, 至 2023年03月31日

  腫瘍学（演習）

  P007, 通年不定, 医学研究科, 4
• 自 2022年04月01日, 至 2023年03月31日

  腫瘍学（実習）

  P008, 通年不定, 医学研究科, 2
• 自 2017年04月, 至 2018年03月

  ゲノム生命科学特論

  通年集中, 生命科学研究科
• 自 2018年04月, 至 2019年03月

  腫瘍学（実習）

  通年不定, 医学研究科
• 自 2018年04月, 至 2019年03月

  腫瘍学（演習）

  通年不定, 医学研究科
• 自 2019年04月, 至 2020年03月

  腫瘍学（修士実習）

  通年不定, 医学研究科
• 自 2019年04月, 至 2020年03月

  腫瘍学（修士演習）

  通年不定, 医学研究科
• 自 2019年04月, 至 2020年03月

  腫瘍学（実習）

  通年不定, 医学研究科
• 自 2019年04月, 至 2020年03月

  腫瘍学（演習）

  通年不定, 医学研究科
• 自 2020年04月, 至 2021年03月

  腫瘍学（修士実習）

  通年不定, 医学研究科
• 自 2020年04月, 至 2021年03月

  腫瘍学（修士演習）

  通年不定, 医学研究科
• 自 2020年04月, 至 2021年03月

  腫瘍学（実習）

  通年不定, 医学研究科
• 自 2020年04月, 至 2021年03月

  腫瘍学（演習）

  通年不定, 医学研究科
• 自 2021年04月, 至 2022年03月

  腫瘍学（修士実習）

  通年不定, 医学研究科
• 自 2021年04月, 至 2022年03月

  腫瘍学（修士演習）

  通年不定, 医学研究科
• 自 2021年04月, 至 2022年03月

  腫瘍学（実習）

  通年不定, 医学研究科
• 自 2021年04月, 至 2022年03月

  腫瘍学（演習）

  通年不定, 医学研究科

博士学位審査

• Chemical induction of splice-neoantigens attenuates tumor growth in a preclinical model of colorectal cancer(スプライスネオ抗原の化学誘導は大腸がん前臨床モデルにおいて腫瘍増殖を抑制する)

  松島　慎吾, 医学研究科, 副査

  2024年03月25日
• Clinicopathological features of cytokeratin 5-positive pulmonary adenocarcinoma(サイトケラチン5 陽性肺腺癌の臨床病理学的特徴)

  寺田　和弘, 医学研究科, 副査

  2024年03月25日
• Branchpoints as potential targets of exon-skipping therapies for genetic disorders(ブランチポイントは遺伝性疾患に対するエクソンスキッピング療法の有望な標的である)

  大原　寛明, 医学研究科, 副査

  2024年01月23日
• Integrative analysis of cancer dependency data and comprehensive phosphoproteomics data revealed the EPHA2-PARD3 axis as a cancer vulnerability in KRAS-mutant colorectal cancer(網羅的大腸癌35細胞株リン酸化プロテオミクスと公共CRISPRスクリーニングデータの統合解析によりEPHA2-PARD3軸がKRAS変異癌の脆弱性となることを明らかにした)

  軍司　大悟, 医学研究科, 副査

  2023年09月25日
• Comprehensive analysis of full-length transcripts reveals novel splicing abnormalities and oncogenic transcripts in liver cancer(完全長転写産物の網羅的解析による肝細胞癌における新規スプラシング異常と発がん性転写産物の解明)

  清瀨　大樹, 医学研究科, 副査

  2023年05月23日
• Familial episodic limb pain in kindreds with novel Nav1.9 mutations(小児四肢疼痛発作症の家系において新規に同定されたNav1.9 遺伝子変異)

  加畑　理咲子, 医学研究科, 副査

  2024年01月23日
• Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia(骨髄性腫瘍におけるEVI1再構成とRNAスプライシング異常の協調機構)

  田中　淳, 医学研究科, 主査

  2023年03月23日
• ILF2 enhances the DNA cytosine deaminase activity of tumor mutator APOBEC3B in multiple myeloma cells(ILF2は骨髄腫細胞において変異原であるAPOBEC3BのDNAシトシン脱アミノ化酵素活性を促進する)

  数馬　安浩, 医学研究科, 副査

  2022年09月26日
• Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia(複合的なゲノム解析がUBTFタンデム重複が小児急性骨髄性白血病において再発性の遺伝子変異と同定する)

  梅田　雅之, 医学研究科, 副査

  2023年03月23日
• Comprehensive genomics in androgen receptor-dependent castration-resistant prostate cancer identifies an adaptation pathway mediated by opioid receptor kappa 1(アンドロゲン受容体依存性去勢抵抗性前立腺癌における opioid receptor kappa 1 を介した適応応答経路の同定)

  牧野　雄樹, 医学研究科, 副査

  2022年11月24日
• DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency (DMRT1を介した生体内での細胞初期化は全能性の特徴を持つヒト胚細胞腫瘍に類似したがんを形成する)

  田口　純平, 医学研究科, 副査

  2022年01月24日
• PTEN is a predictive biomarker of trastuzumab resistance and prognostic factor in HER2-overexpressing gastroesophageal adenocarcinoma (PTENはHER2陽性胃癌・食道腺癌においてTrastuzumab抵抗性を予測するバイオマーカーであり、予後因子である)

  横山　大受, 医学研究科, 副査

  2021年11月24日
• Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal Cancer (同一患者由来の大腸がんオルガノイド比較解析によるOLFM4陽性がん幹細胞の同定と転移再発に伴う細胞多様性の変化)

  岡本　拓也, 医学研究科, 副査

  2021年11月24日
• HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis (HBO1とMLLは結合しAF4/ENL/P-TEFb複合体による白血化を促進する)

  髙橋　慧, 医学研究科, 副査

  2022年03月23日
• Identification of the Minimum Requirements for Successful Haematopoietic Stem Cell Transplantation (造血幹細胞移植成立のための必要最小条件の同定)

  西　克幸, 医学研究科, 副査

  2022年03月23日
• Hes1 is essential in proliferating ductal cell-mediated development of intrahepatic cholangiocarcinoma (Hes1遺伝子は細胆管由来の肝内胆管癌の発生に重要な役割を果たす)

  松森　友昭, 医学研究科, 副査

  2021年05月24日
• Azacitidine is a potential therapeutic drug for pyridoxine-refractory female X-linked sideroblastic anemia (アザシチジンはピリドキシン不応性の女性X連鎖性鉄芽球性貧血の治療薬となり得る)

  大棟　有紀, 医学研究科, 副査

  2022年03月23日
• Gene expression profiles of liver cancer cell lines reveal two hepatocyte-like and fibroblast-like clusters (肝癌セルラインにおける遺伝子発現プロファイルは、肝細胞様、線維芽細胞様の2つのクラスターを明らかにする)

  福山　啓太, 医学研究科, 副査

  2021年07月26日
• Suppression of malignant rhabdoid tumors through Chb-M′-mediated RUNX1 inhibition (Chb-M′を介したRUNX1阻害は悪性ラブドイド腫瘍の増殖を抑制する)

  大封　智雄, 医学研究科, 主査

  2022年03月23日

大学運営

全学運営(役職等)

• 自 2015年09月11日, 至 2015年12月31日

  ヒトゲノム・遺伝子解析研究管理委員会 委員

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• 自 2020年11月26日

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  柳井基金運営委員会委員