Retroviral integration into topologically-interlocked DNAs to probe the role of DNA structure and screen viral inhibitors
Grant-in-Aid for Scientific Research (C)
Basic Section 37010:Bio-related chemistry
Kyoto University
Rajendran A.
From 01 Apr. 2021, To 31 Mar. 2024, Project Closed
DNA origami;DNA nanotechnology;Structural biology;Nucleic acids chemistry;DNA-protein interaction;DNA origami stability;Topological DNA;DNA-protein interactions;Atomic force microscopy;Viral proteins;Topological structures;Minicircle DNA;Interlocked structures;DNA minicircles;HS-AFM;Viral inhibitor;Viral integrase;Drug screening