Basic Information

Faculty

• 農学部

Professional Memberships

• バイオインダストリー協会
• 日本ビタミン学会
• 日本生化学会
• 日本生物工学会
• 日本農芸化学会

Academic Degree

• 修士（農学）(京都大学)
• 博士（農学）(京都大学)

Academic Resume (Graduate Schools)

• 京都大学, 大学院農学研究科博士後期課程農芸化学専攻, 修了
• 京都大学, 大学院農学研究科修士課程農芸化学専攻, 修了

Academic Resume (Undergraduate School/Majors)

• 京都大学, 農学部農芸化学科, 卒業

Research History

• From 1994, To 1995

  日本学術振興会特別研究員
• From 1994, To 1995

  Research fellow of JSPS

Language of Instruction

• English

ID,URL

• ORCID ID

  0000-0003-2741-621X

• J-Global ID

  200901030926965683

researchmap URL

• https://researchmap.jp/ogawa_jun

Research

Research Topics, Overview of the research

• Research Topics

  Screening and development of novel mcrobial function

• Overview of the research

  Screening and development of novel mcrobial function

Research Interests

• 応用微生物学
• Applied Microbioligy

Research Areas

• Life sciences, Applied biochemistry

Papers

• Intracellular electron donor stripping to identify electron donors of indigo reduction

  Hiroki Tanaka; Mayu Kikuchi; Kenji Kano; Eiji Sakuradani; Jun Ogawa; Kouichi Kuroda; Michiki Takeuchi

  Bioscience, Biotechnology, and Biochemistry, 09 Apr. 2025

  
• Effects of lignin on indigo-reducing activity and indigo particle size in indigo dye suspensions

  Kasumi Nakagawa; Haruka Ohata; Michiki Takeuchi; Momoka Matsunaga; Keisei Sowa; Takaiku Sakamoto; Akinori Ando; Chikako Asada; Jun Ogawa; Kenji Kano; Eiji Sakuradani

  Bioscience, Biotechnology, and Biochemistry, 26 Nov. 2024

  
• The omega-3 postbiotic trans-10-cis-15-octadecadienoic acid attenuates contact hypersensitivity in mice through downregulation of vascular endothelial growth factor A

  Azusa Saika; Takahiro Nagatake; Shigenobu Kishino; Nahoko Kitamura; Tetsuya Honda; Koji Hosomi; Prabha Tiwari; Eri Node; Soichiro Kawai; Saki Kondo; Kei Ishida; Kenji Kabashima; Jun Ogawa; Jun Kunisawa

  Frontiers in Cellular and Infection Microbiology, 22 May 2024

  
• An isoflavone catabolism gene cluster underlying interkingdom interactions in the soybean rhizosphere.

  Noritaka Aoki; Tomohisa Shimasaki; Wataru Yazaki; Tomoaki Sato; Masaru Nakayasu; Akinori Ando; Shigenobu Kishino; Jun Ogawa; Sachiko Masuda; Arisa Shibata; Ken Shirasu; Kazufumi Yazaki; Akifumi Sugiyama

  ISME communications, Jan. 2024

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• A gut microbial metabolite of linoleic acid ameliorates liver fibrosis by inhibiting TGF-β signaling in hepatic stellate cells

  Nanaho Kasahara; Yukiko Imi; Reina Amano; Masakazu Shinohara; Kumiko Okada; Yusei Hosokawa; Makoto Imamori; Chiaki Tomimoto; Jun Kunisawa; Shigenobu Kishino; Jun Ogawa; Wataru Ogawa; Tetsuya Hosooka

  Scientific Reports, 03 Nov. 2023

  
• Discovery of an isoflavone oxidative catabolic pathway in legume root microbiota

  Noritaka Aoki; Tomohisa Shimasaki; Wataru Yazaki; Tomoaki Sato; Masaru Nakayasu; Akinori Ando; Shigenobu Kishino; Jun Ogawa; Sachiko Masuda; Arisa Shibata; Ken Shirasu; Kazufumi Yazaki; Akifumi Sugiyama

  08 Aug. 2023

  
• The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling

  Miki Ando; Kazuki Nagata; Naoto Ito; Sakura Noguchi; Asuka Yamamoto; Naoki Kodama; Takuya Yashiro; Masakazu Hachisu; Gaku Ichihara; Shigenobu Kishino; Masayuki Yamamoto; Jun Ogawa; Chiharu Nishiyama

  bioRxiv, 22 Feb. 2023, Peer-reviewed

  
• Structural differences in bacterial lipopolysaccharides determine atherosclerotic plaque progression by regulating the accumulation of neutrophils

  Yoshihiro Saito; Tomoya Yamashita; Naofumi Yoshida; Takuo Emoto; Shintaro Takeda; Tokiko Tabata; Masakazu Shinohara; Shigenobu Kishino; Yuta Sugiyama; Nahoko Kitamura; Hiroyuki Yamamoto; Tomofumi Takaya; Jun Ogawa; Ken-ichi Hirata

  Atherosclerosis, Oct. 2022, Peer-reviewed

  
• Dietary-protein sources modulate host susceptibility to Clostridioides difficile infection through the gut microbiota

  Kyosuke Yakabe; Seiichiro Higashi; Masahiro Akiyama; Hiroshi Mori; Takumi Murakami; Atsushi Toyoda; Yuta Sugiyama; Shigenobu Kishino; Kenji Okano; Akiyoshi Hirayama; Aina Gotoh; Shunyi Li; Takeshi Mori; Takane Katayama; Jun Ogawa; Shinji Fukuda; Koji Hase; Yun-Gi Kim

  Cell Reports, Sep. 2022, Peer-reviewed

  
• Generation of Fusarium oxysporum-suppressive soil with non-soil carriers using a multiple-parallel-mineralization technique.

  Jamjan Meeboon; Akinori Ando; Jun Ogawa; Kenji Miyamoto; Yasuo Kato; Makoto Shinohara

  Scientific reports, 13 May 2022

  
• Medium-chain triglycerides inhibit long-chain triglyceride-induced GIP secretion through GPR120-dependent inhibition of CCK

  Yuki Murata; Norio Harada; Shigenobu Kishino; Kanako Iwasaki; Eri Ikeguchi-Ogura; Shunsuke Yamane; Tomoko Kato; Yoshinori Kanemaru; Akiko Sankoda; Tomonobu Hatoko; Sakura Kiyobayashi; Jun Ogawa; Akira Hirasawa; Nobuya Inagaki

  iScience, Sep. 2021, Peer-reviewed

  
• A possible beneficial effect of Bacteroides on faecal lipopolysaccharide activity and cardiovascular diseases

  Naofumi Yoshida; Tomoya Yamashita; Shigenobu Kishino; Hikaru Watanabe; Kengo Sasaki; Daisuke Sasaki; Tokiko Tabata; Yuta Sugiyama; Nahoko Kitamura; Yoshihiro Saito; Takuo Emoto; Tomohiro Hayashi; Tomoya Takahashi; Masakazu Shinohara; Ro Osawa; Akihiko Kondo; Takuji Yamada; Jun Ogawa; Ken-ichi Hirata

  Scientific Reports, Dec. 2020, Peer-reviewed

  
• 乳酸菌由来脂肪酸によるヒト小腸上皮細胞の脂質代謝制御の解析

  野口 惇; 清水 誠; 高橋 裕; 岸野 重信; 小川 順; 山内 祥生; 佐藤 隆一郎

  日本栄養・食糧学会大会講演要旨集, Apr. 2020

  
• 口腔細菌の脂質代謝に由来する機能性脂肪酸HYAは歯肉上皮バリア機能を強化することで歯周炎の発症を抑制する

  山田 実生; 高橋 直紀; 松田 由実; 佐藤 圭祐; 横地 麻衣; Sulijaya Benso; 多部田 康一; 山崎 和久; 村上 伸也; 小川 順; 岸野 重信

  新潟歯学会雑誌, Dec. 2018

  
• 新規機能性脂肪酸の歯肉上皮細胞における抗酸化ストレス作用の検討

  横地 麻衣; 高橋 直紀; 松田 由実; 山田 実生; Sulijaya Benso; 多部田 康一; 山崎 和久; 小川 順; 岸野 信重

  新潟歯学会雑誌, Dec. 2018

  
• レシチンの乳牛への給与がルーメン内の揮発性脂肪酸(VFA)産生量および乳生産におよぼす効果

  雑賀 あずさ; 泉 賢一; 岸野 重信; 井上 亮; 木村 功; 斎藤 三四郎; 小川 順

  日本畜産学会大会講演要旨集, Sep. 2017

  
• 泌乳牛へのレシチン投与が乳生産およびルーメン発酵に及ぼす影響

  伊藤 有唯; 栗田 紗希; 小川 実咲; 雑賀 あずさ; 北村 苗穂子; 岸野 重信; 小川 順; 木村 功; 齋藤 三四郎; 泉 賢一

  北海道畜産草地学会報, Aug. 2017

  
• Gene identification and enzymatic characterization of the initial enzyme in pyrimidine oxidative metabolism, uracil-thymine dehydrogenase

  Chee-Leong Soong; Kengo Deguchi; Michiki Takeuchi; Syoko Kozono; Nobuyuki Horinouchi; Dayong Si; Makoto Hibi; Sakayu Shimizu; Jun Ogawa

  Journal of Bioscience and Bioengineering, Mar. 2024

  
• One-Pot Synthesis of Useful S-Substituted-l-cysteine Sulfoxides Using Genetically Engineered Escherichia coli

  Taku Mizutani; Ryotaro Hara; Michiki Takeuchi; Makoto Hibi; Makoto Ueda; Jun Ogawa

  Journal of Agricultural and Food Chemistry, 28 Feb. 2024

  
• 腸内細菌における食事成分・薬効成分代謝の解析と代謝物の生理機能

  小川 順; 原 良太郎; 安藤 晃規; 竹内 道樹; 岸野 重信

  生化学, 25 Aug. 2023, Peer-reviewed

  
• The relationship between unique gut microbiome-derived lipid metabolites and subsequent revascularization in patients who underwent percutaneous coronary intervention

  Daichi Fujimoto; Masakazu Shinohara; Hiroyuki Kawamori; Takayoshi Toba; Shunsuke Kakizaki; Koichi Nakamura; Satoru Sasaki; Tomoyo Hamana; Hiroyuki Fujii; Yuto Osumi; Naomi Hayasaka; Shigenobu Kishino; Jun Ogawa; Ken-ichi Hirata; Hiromasa Otake; Show

  Atherosclerosis, 04 May 2023, Peer-reviewed

  
• Characterisation of an Escherichia coli line that completely lacks ribonucleotide reduction yields insights into the evolution of parasitism and endosymbiosis

  Samantha DM Arras; Nellie SibaevaRyan; J Catchpole; Nobuyuki Horinouchi; Dayong Si; Alannah M Rickerby; Kengo Deguchi; Makoto Hibi; Koichi Tanaka; Michiki Takeuchi; Jun Ogawa; Anthony M Poole

  eLife, 06 Apr. 2023, Peer-reviewed

  
• 新規脱窒材を活用したサクラマスの閉鎖循環型飼育システムー飼育試験と北海道での利活用―

  田園大樹; 安藤大成; 室岡瑞恵; 山口 文; 安富亮平; 後藤久典; 小川 順; 安藤晃規

  月刊 養殖ビジネス, 2023, Peer-reviewed, Corresponding author

  
• Food Bio Plus研究会がめざす課題解決の方向性(1) Food Bio Plus研究会設立宣言～「人と社会と地球」の健康を目指して～

  小川 順

  バイオサイエンスとインダストリー, 2022, Peer-reviewed, Lead author

  
• Hannaella oleicumulans sp. nov. and Hannaella higashiohmiensis sp. nov., two novel oleaginous basidiomycetous yeast species

  Ayumi Tanimura; Hikaru Adachi; Koichi Tanabe; Jun Ogawa; Jun Shima

  International Journal of Systematic and Evolutionary Microbiology, 20 Sep. 2023

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• Alkane production from fatty alcohols by the combined reactions catalyzed by an alcohol dehydrogenase and an aldehyde-deformylating oxygenase

  Yu-An Sui; Satoshi Maruyama; Natsumi Okada; Masakazu Ito; Masayoshi Muramatsu; Shusei Obata; Jun Ogawa; Shigenobu Kishino

  Bioscience, Biotechnology, and Biochemistry, 08 May 2023

  
• Mead acid production by disruption of Δ12-desaturase gene in Mortierella alpina 1S-4

  Hiroshi Kikukawa; Akinori Ando; Asuka Hannya; Mohd Fazli Farida Asras; Tomoyo Okuda; Takaiku Sakamoto; Kiyotaka Y. Hara; Eiji Sakuradani; Jun Ogawa

  Journal of Bioscience and Bioengineering, Aug. 2023

  
• α-Tomatine degradation to tomatidine by food-related Aspergillus species belonging to the section Nigri

  Chun-Wai Hui; Shigenobu Kishino; Yuki Nakatani; Jun Ogawa

  Bioscience, Biotechnology, and Biochemistry, 20 Mar. 2023

  
• Isolation and characterization of the ω3-docosapentaenoic acid-producing microorganism Aurantiochytrium sp. T7

  Chang-Yu Wu; Tomoyo Okuda; Akinori Ando; Ayami Hatano; Hiroshi Kikukawa; Jun Ogawa

  Journal of Bioscience and Bioengineering, Mar. 2022, Peer-reviewed

  
• An ACE2, SARS-CoV-2 spike protein binding protein, -like enzyme isolated from food-related microorganisms

  Izza Nur Laily; Michiki Takeuchi; Taku Mizutani; Jun Ogawa

  Bioscience, Biotechnology, and Biochemistry, 30 Mar. 2023

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• Comprehensive analysis of fatty acid metabolites produced by gut microbiota using LC-MS/MS-based lipidomics

  Kowa Tsuji; Wataru Shimada; Shigenobu Kishino; Jun Ogawa; Makoto Arita

  Medical Mass Spectrometry, Aug. 2022, Peer-reviewed

  
• 口腔細菌脂質代謝に由来する機能性脂肪酸HYAは歯肉上バリア機能の低下を抑制する

  山田 実生; 高橋 直紀; 松田 由実; 佐藤 圭祐; 横地 麻衣; 多部田 康一; 中島 貴子; 山崎 和久; 小川 順; 岸野 信重

  日本歯周病学会会誌, Sep. 2016

  
• Utilizing Alcohol for Alkane Biosynthesis by Introducing a Fatty Alcohol Dehydrogenase

  Yu-An Sui; Shigenobu Kishino; Satoshi Maruyama; Masakazu Ito; Masayoshi Muramatsu; Shusei Obata; Jun Ogawa

  Applied and Environmental Microbiology, 23 Nov. 2022, Peer-reviewed

  
• Lactic acid bacteria-derived γ-linolenic acid metabolites are PPARδ ligands that reduce lipid accumulation in human intestinal organoids.

  Makoto Noguchi; Makoto Shimizu; Peng Lu; Yu Takahashi; Yoshio Yamauchi; Shintaro Sato; Hiroshi Kiyono; Shigenobu Kishino; Jun Ogawa; Koji Nagata; Ryuichiro Sato

  Journal of Biological Chemistry, Sep. 2022, Peer-reviewed

  
• Screening of novel microbial enzymes for the production of biologically and chemically useful compounds.

  S Shimizu; J Ogawa; M Kataoka; M Kobayashi

  Advances in biochemical engineering/biotechnology, 1997

  
• Analysis of astragaloside IV metabolism to cycloastragenol in human gut microorganism, bifidobacteria, and lactic acid bacteria

  Daniel M Takeuchi; Shigenobu Kishino; Yuuki Ozeki; Hiroyuki Fukami; Jun Ogawa

  Bioscience, Biotechnology, and Biochemistry, 23 Sep. 2022

  
• Production of GABA-enriched tomato juice by Lactiplantibacillus plantarum KB1253

  Yuki Nakatani; Tetsuya Fukaya; Shigenobu Kishino; Jun Ogawa

  Journal of Bioscience and Bioengineering, Sep. 2022

  
• Characterization of regioselective glycosyltransferase of Rhizobium pusense JCM 16209T useful for resveratrol 4′-O-α-d-glucoside production

  Shota Kimoto; Michiki Takeuchi; Shigenobu Kishino; Yudai Itagaki; Ryotaro Hara; Nahoko Kitamura; Natsumi Okada; Si-Bum Park; Akinori Ando; Makoto Ueda; Jun Ogawa

  Journal of Bioscience and Bioengineering, Jul. 2022

  
• Quantification of leuco-indigo in indigo-dye-fermenting suspension by normal pulse voltammetry

  Mayu Kikuchi; Keisei Sowa; Michiki Takeuchi; Kasumi Nakagawa; Momoka Matsunaga; Akinori Ando; Kenji Kano; Jun Ogawa; Eiji Sakuradani

  Journal of Bioscience and Bioengineering, Jul. 2022

  
• 3.乳酸菌による共役リノール酸(CLA)生産に関与する酵素系の解明(その1)(第406回研究協議会研究発表要旨,ビタミンB研究委員会)

  清水 昌; 岸野 重信; 小川 順; 横関 健三

  ビタミン, 2007

  
• Identification of tryptophanase from Escherichia coli for the synthesis of S-allyl-l-cysteine and related S-substituted cysteine derivatives

  Taku Mizutani; Ryotaro Hara; Takayuki Iihoshi; Shoko Kozono; Michiki Takeuchi; Makoto Hibi; Satomi Takahashi; Makoto Ueda; Jun Ogawa

  Journal of Bioscience and Bioengineering, Jun. 2022

  
• l-Tryptophan-starved cultivation enhances S-allyl-l-cysteine synthesis in various food-related microorganisms.

  Taku Mizutani; Ryotaro Hara; Michiki Takeuchi; Kazuo Yamagishi; Yoshinori Hirao; Kenichi Mori; Makoto Hibi; Makoto Ueda; Jun Ogawa

  Bioscience, biotechnology, and biochemistry, 24 May 2022

  
• Semi‐rational Engineering of a Promiscuous Fatty Acid Hydratase for Alteration of Regioselectivity

  Yan Zhang; Niels Mikkel Dyrby Breum; Sune Schubert; Negin Hashemi; Rikke Kyhnau; Marius Sandholt Knauf; Masuthan Mathialakan; Michiki Takeuchi; Shigenobu Kishino; Jun Ogawa; Peter Kristensen; Zheng Guo; Bekir Engin Eser

  ChemBioChem, 16 Feb. 2022

  
• Isolation and characterization of indigo-reducing bacteria and analysis of microbiota from indigo fermentation suspensions

  Kasumi Nakagawa; Michiki Takeuchi; Manami Tada; Momoka Matsunaga; Masami Kugo; Suzuna Kiyofuji; Mayu Kikuchi; Kazuya Yomota; Takaiku Sakamoto; Kenji Kano; Jun Ogawa; Eiji Sakuradani

  Bioscience, Biotechnology, and Biochemistry, 24 Jan. 2022

  
• 中鎖脂肪酸トリグリセリドは長鎖脂肪酸トリグリセリド摂取時のGIP分泌を抑制し肥満を軽減する

  村田 由貴; 原田 範雄; 岸野 重信; 山根 俊介; 岩崎 可南子; 加藤 朋子; 池口 絵理; 金丸 良徳; 波床 朋信; 許 櫻華; 小川 順; 平澤 明; 稲垣 暢也

  肥満研究, Oct. 2019

  
• Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques

  Takahiro Nagatake; Shigenobu Kishino; Emiko Urano; Haruka Murakami; Nahoko Kitamura; Kana Konishi; Harumi Ohno; Prabha Tiwari; Sakiko Morimoto; Eri Node; Jun Adachi; Yuichi Abe; Junko Isoyama; Kento Sawane; Tetsuya Honda; Asuka Inoue; Akiharu Uwamizu; Takashi Matsuzaka; Yoichi Miyamoto; So-ichiro Hirata; Azusa Saika; Yuki Shibata; Koji Hosomi; Ayu Matsunaga; Hitoshi Shimano; Makoto Arita; Junken Aoki; Masahiro Oka; Akira Matsutani; Takeshi Tomonaga; Kenji Kabashima; Motohiko Miyachi; Yasuhiro Yasutomi; Jun Ogawa; Jun Kunisawa

  Mucosal Immunology, 10 Jan. 2022

  
• Microbial production of hydroxy fatty acids utilizing crude glycerol

  Naomi Murakawa; Takaiku Sakamoto; Mizuho Kanoh; Si-Bum Park; Shigenobu Kishino; Jun Ogawa; Eiji Sakuradani

  Biocatalysis and Agricultural Biotechnology, Jan. 2022

  
• Enzyme systems involved in glucosinolate metabolism in Companilactobacillus farciminis KB1089

  Hiroko Watanabe; Riku Usami; Shigenobu Kishino; Kengo Osada; Yudai Aoki; Hironobu Morisaka; Masatomo Takahashi; Yoshihiro Izumi; Takeshi Bamba; Wataru Aoki; Hiroyuki Suganuma; Jun Ogawa

  Scientific Reports, Dec. 2021

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• 3つの不斉中心を同時制御可能なカルボニル還元酵素の開発

  日比 慎; 宮川 拓也; 田之倉 優; 小川 順

  バイオサイエンスとインダストリー, Nov. 2019

  
• ヒドロキシ-D-アミノ酸の酵素合成法の開発

  角田 洋輔; 北澤 宏明; 岸本 高英; 杉山 明生; 小園 祥子; 日比 慎; 小川 順

  日本薬学会年会要旨集, Mar. 2017

  
• 構造情報に基づく4-HIL合成酵素の立体選択性の制御

  石 玄; 宮川 拓也; 中村 顕; 侯 峰; 日比 慎; 小川 順; 田之倉 優

  バイオイメージング, Aug. 2016

  
• A three-component monooxygenase from Rhodococcus wratislaviensis may expand industrial applications of bacterial enzymes

  Makoto Hibi; Dai Fukuda; Chihiro Kenchu; Masutoshi Nojiri; Ryotaro Hara; Michiki Takeuchi; Shunsuke Aburaya; Wataru Aoki; Kimihiko Mizutani; Yoshihiko Yasohara; Mitsuyoshi Ueda; Bunzo Mikami; Satomi Takahashi; Jun Ogawa

  Communications Biology, Dec. 2021, Peer-reviewed

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• Effects of the engineering of a single binding pocket residue on specificity and regioselectivity of hydratases from Lactobacillus Acidophilus

  Yan Zhang; Bekir Engin Eser; Georgios Kougioumtzoglou; Zekiye Eser; Michal Poborsky; Shigenobu Kishino; Michiki Takeuchi; Jun Ogawa; Peter Kristensen; Zheng Guo

  Biochemical Engineering Journal, Jul. 2021, Peer-reviewed

  
• Characterization of xanthine oxidase from Cellulosimicrobium funkei possessing hypoxanthine‐metabolizing activity

  I. Kozono; M. Takeuchi; S. Kozono; A. Satomura; W. Aoki; M. Hibi; J. Ogawa

  Journal of Applied Microbiology, Jun. 2021, Peer-reviewed, Last author

  
• Characterization of ω3 fatty acid desaturases from oomycetes and their application toward eicosapentaenoic acid production in Mortierella alpina

  Brian K H Mo; Akinori Ando; Ryohei Nakatsuji; Tomoyo Okuda; Yuki Takemoto; Hiroyuki Ikemoto; Hiroshi Kikukawa; Takaiku Sakamoto; Eiji Sakuradani; Jun Ogawa

  Bioscience, Biotechnology, and Biochemistry, 24 Apr. 2021, Peer-reviewed, Last author

  
• IT・AIによるスマート発酵産業

  小川 順

  Enzyme Wave, Apr. 2021, Peer-reviewed, Lead author

  
• 微生物に見いだした新規α—アミノイソ酪酸代謝ならびに代謝酵素群の解析

  小川 順; 福田 大; 間中千尋; 高橋里美; 日比 慎

  ビタミン, 25 Feb. 2021, Peer-reviewed, Lead author

  
• Voltammetric in-situ monitoring of leuco-indigo in indigo-fermenting suspensions

  Kasumi Nakagawa; Michiki Takeuchi; Mayu Kikuchi; Manami Tada; Takaiku Sakamoto; Kenji Kano; Jun Ogawa; Eiji Sakuradani

  Journal of Bioscience and Bioengineering, Feb. 2021, Peer-reviewed

  
• Mechanistic Insights into Indigo Reduction in Indigo Fermentation: A Voltammetric Study

  Kasumi NAKAGAWA; Michiki TAKEUCHI; Mayu KIKUCHI; Suzuna KIYOFUJI; Masami KUGO; Takaiku SAKAMOTO; Kenji KANO; Jun OGAWA; Eiji SAKURADANI

  Electrochemistry, 05 Jan. 2021, Peer-reviewed

  
• 新規脂肪族アルコール脱水素酵素のバイオアルカン生産への応用

  小川 順; 丸山悟史; 竹内ダニエル誠; 岸野重信

  ビタミン, 25 Dec. 2020, Peer-reviewed

  
• Cloning and characterization of a recombinant α-glucosidase from Ensifer adhaerens NBRC 100388 and evaluation of its glucosyl transfer activity

  Tatsuya Suzuki; Miyu Fukaya; Kazuki Takahashi; Michiki Takeuchi; Ryotaro Hara; Jun Ogawa; Makoto Ueda

  Biocatalysis and Agricultural Biotechnology, Nov. 2020, Peer-reviewed

  
• 食事脂質の腸内細菌代謝から考える健康増進

  小川 順; 岸野重信

  日本食品免疫学会講演記録集, 01 Nov. 2020, Peer-reviewed

  
• 食事成分の腸内細菌代謝を介した健康制御

  小川 順; 岸野重信

  日本食品免疫学会講演記録集, 01 Nov. 2020, Peer-reviewed

  
• Purification and characterization of molybdenum-containing aldehyde dehydrogenase that oxidizes benzyl maltol derivative from Pseudomonas nitroreducens SB32154

  Iori Kozono; Makoto Hibi; Michiki Takeuchi; Jun Ogawa

  Bioscience, Biotechnology, and Biochemistry, 01 Nov. 2020, Peer-reviewed

  
• 腸内細菌が産生する食事脂質代謝物とその生理機能

  岸野重信; 米島靖記; 小川 順

  生物工学会誌, 25 Oct. 2020, Peer-reviewed

  
• 腸内細菌によるω3 脂肪酸代謝と代謝物の生理機能

  岸野重信; 小川 順

  BIO INDUSTRY, 12 Oct. 2020, Peer-reviewed

  
• 油糧微生物による種々のω3 脂肪酸含有油脂の発酵生産

  安藤晃規; 奥田知生; 菊川寛史; 阪本鷹行; 櫻谷英治; 小川 順

  BIO INDUSTRY, 12 Oct. 2020, Peer-reviewed

  
• 特集にあたって －ω-3脂肪酸をつくる・理解する・展開する－

  小川 順

  BIO INDUSTRY, 12 Oct. 2020, Peer-reviewed

  
• ラビリンチュラ類によるω3-docosapentaenoic acid（ω3-DPA）の生産

  安藤晃規; 奥田知生; 波多野文美; 菊川寛史; 松山恵介; 小川 順

  生物工学会誌, 25 Sep. 2020, Peer-reviewed

  
• Mortierella alpina 1S-4の分子育種による種々のPUFAの生産

  菊川寛史; 奥田知生; 安藤晃規; 櫻谷英治; 小川 順

  生物工学会誌, 98(9), 465-468, 25 Sep. 2020, Peer-reviewed

  
• 脂質がつなぐもの：生物工学的脂質研究が導く新しい学際研究と産業（前編） 特集によせて

  小川 順

  生物工学会誌, 25 Sep. 2020, Peer-reviewed

  
• The anti-inflammatory effect of the gut lactic acid bacteria-generated metabolite 10-oxo-cis-6,trans-11-octadecadienoic acid on monocytes

  Shuhei Hagiwara; Kazuki Nagata; Kazumi Kasakura; Fumiya Sakata; Shigenobu Kishino; Jun Ogawa; Takuya Yashiro; Chiharu Nishiyama

  Biochemical and Biophysical Research Communications, Sep. 2020, Peer-reviewed

  
• Evaluation of electron-transferring cofactor mediating enzyme systems involved in urolithin dehydroxylation in Gordonibacter urolithinfaciens DSM 27213

  Hiroko Watanabe; Shigenobu Kishino; Masatake Kudoh; Hiroaki Yamamoto; Jun Ogawa

  Journal of Bioscience and Bioengineering, May 2020, Peer-reviewed

  
• Gut microbial fatty acid metabolites (KetoA and KetoC) affect the progression of nonalcoholic steatohepatitis and reverse cholesterol transport metabolism in mouse model.

  Neng Tanty Sofyana; Jiawen Zheng; Yuki Manabe; Yuta Yamamoto; Shigenobu Kishino; Jun Ogawa; Tatsuya Sugawara

  Lipids, Mar. 2020, Peer-reviewed

  
• A bacterial metabolite induces Nrf2-mediated anti-oxidative responses in gingival epithelial cells by activating the MAPK signaling pathway.

  Mai Yokoji-Takeuchi; Naoki Takahashi; Miki Yamada-Hara; Benso Sulijaya; Takahiro Tsuzuno; Yukari Aoki-Nonaka; Koichi Tabeta; Shigenobu Kishino; Jun Ogawa; Kazuhisa Yamazaki

  Archives of oral biology, Feb. 2020, Peer-reviewed

  
• Application of Enzymatic Reactions Involving Electron Transfer and Energy Supply for the Production of Useful Chemicals

  Jun Ogawa; Michiki Takeuchi; Akinori Ando; Ryotaro Hara; Makoto Hibi; Shigenobu Kishino

  Electron-Based Bioscience and Biotechnology, 2020, Peer-reviewed

  
• 第19回日本油化学会オレオサイエンス賞受賞によせて –これまでの脂肪酸研究を振り返って–

  岸野重信; 米島靖記; 小川 順

  オレオサイエンス, 2020, Peer-reviewed

  
• 複合微生物を拓く―窒素循環を駆動する硝化複合微生物系モデルの構築―

  安藤晃規; 小川 順

  環境バイオテクノロジー学会誌, 2020, Peer-reviewed

  
• 食品機能と微生物機能の相互作用 ー食事脂質の微生物代謝を例にー

  小川 順

  食品加工技術, 2020, Peer-reviewed

  
• ω3-Docosapentaenoic Acid (ω3-DPA) Production by Labyrinthulea Aurantiochytrium sp. T7

  Akinori ANDO; Tomoyo OKUDA; Ayami HATANO; Hiroshi KIKUKAWA; Keisuke MATSUYAMA; Jun OGAWA

  Oleoscience, 2020, Peer-reviewed

  
• Fermentative Production of Oils Rich in Polyunsaturated Fatty Acids by the Molecularly Bred Strains of Mortierella alpina 1S-4

  Jun OGAWA; Tomoyo OKUDA; Hiroshi KIKUKAWA; Akinori ANDO

  Oleoscience, 2020, Peer-reviewed

  
• 17(S),18(R)-epoxyeicosatetraenoic acid generated by cytochrome P450 BM-3 from Bacillus megaterium inhibits the development of contact hypersensitivity via G-protein-coupled receptor 40-mediated neutrophil suppression.

  Azusa Saika; Takahiro Nagatake; Shigenobu Kishino; Si-Bum Park; Tetsuya Honda; Naomi Matsumoto; Michiko Shimojou; Sakiko Morimoto; Prabha Tiwari; Eri Node; So-Ichiro Hirata; Koji Hosomi; Kenji Kabashima; Jun Ogawa; Jun Kunisawa

  FASEB bioAdvances, Jan. 2020, Peer-reviewed

  
• Antimicrobial function of the polyunsaturated fatty acid KetoC in an experimental model of periodontitis.

  Benso Sulijaya; Miki Yamada-Hara; Mai Yokoji-Takeuchi; Yumi Matsuda-Matsukawa; Kyoko Yamazaki; Aoi Matsugishi; Takahiro Tsuzuno; Keisuke Sato; Yukari Aoki-Nonaka; Naoki Takahashi; Shigenobu Kishino; Jun Ogawa; Koichi Tabeta; Kazuhisa Yamazaki

  Journal of periodontology, Dec. 2019, Peer-reviewed

  
• 食事脂質の腸内細菌代謝を介した健康増進

  小川 順; 岸野重信

  アグリバイオ, Dec. 2019

  
• 16S rRNA gene amplicon sequencing of microbiota in polybutylene succinate adipate-packed denitrification reactors used for water treatment of land-based recirculating aquaculture systems

  Takeshi Yamada; Masako Hamada; Miku Nakagawa; Nobukazu Sato; Akinori Ando; Jun Ogawa; Mari Yasuda; Tomoki Kawagishi

  Microbiology Resource Announcements, Nov. 2019, Peer-reviewed

  
• Gut microbial metabolites of linoleic acid are metabolized by accelerated peroxisomal β-oxidation in mammalian cells.

  Katsuya Morito; Ryota Shimizu; Nahoko Kitamura; Si-Bum Park; Shigenobu Kishino; Jun Ogawa; Tatsuya Fukuta; Kentaro Kogure; Tamotsu Tanaka

  Biochimica et biophysica acta. Molecular and cell biology of lipids, Nov. 2019, Peer-reviewed

  
• Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids.

  Junki Miyamoto; Miki Igarashi; Keita Watanabe; Shin-Ichiro Karaki; Hiromi Mukouyama; Shigenobu Kishino; Xuan Li; Atsuhiko Ichimura; Junichiro Irie; Yukihiko Sugimoto; Tetsuya Mizutani; Tatsuya Sugawara; Takashi Miki; Jun Ogawa; Daniel J Drucker; Makoto Arita; Hiroshi Itoh; Ikuo Kimura

  Nature communications, 05 Sep. 2019, Peer-reviewed

  
• Rational engineering of hydratase from Lactobacillus acidophilus reveals critical residues directing substrate specificity and regioselectivit

  B. E. Eser; M. Poborsky; R. Dai; S. Kishino; A. Ljubic; M. Takeuchi; C. Jacobsen; J. Ogawa; P. Kristensen; Z. Guo

  Chembiochem, Aug. 2019, Peer-reviewed

  
• 食と健康をつなぐ腸内細菌の脂肪酸代謝と代謝物の生理機能

  小川 順; 岸野重信

  生化学, Aug. 2019, Peer-reviewed

  
• 腸内細菌による脂肪酸代謝と疾患制御

  岸野重信; 小川 順

  医学のあゆみ, Jun. 2019

  
• 食を豊かにする発酵・醸造－微生物による食材・食品の化学変換－

  小川 順

  月刊 フードケミカル, Jun. 2019, Peer-reviewed

  
• 腸内細菌が産生する食事脂質代謝物の機能解析と応用

  岸野重信; 米島靖記; 小川 順

  オレオサイエンス, Apr. 2019, Invited

  
• 腸内細菌における食品成分代謝研究と健康増進への応用

  小川 順; 岸野重信

  食品と開発, Apr. 2019, Peer-reviewed

  
• 腸内細菌が産生する機能性脂肪酸の抗ヘリコバクター属活性

  松井英則; 岸野重信; 小川 順

  BIO INDUSTRY, Mar. 2019, Peer-reviewed

  
• 腸内細菌の不飽和脂肪酸代謝と代謝産物の生理機能

  岸野重信; 小川 順

  FOOD STYLE 21, Mar. 2019, Peer-reviewed

  
• 酵母を用いたバイオマスからの油脂生産

  谷村あゆみ; 小川 順; 島 純; 高島昌子

  クリーンエネルギー, 2019, Peer-reviewed

  
• 脂質をつくる・理解する・発信する

  小川 順

  脂質生化学研究Circular, 2019, Peer-reviewed

  
• Microbial Cyclic Imide Metabolism and Its Biotechnological Application

  Ogawa, J; C.L. Soong; N. Horinouchi; M. Nojiri; M. Takeuchi; M. Hibi

  Imides, 2019, Peer-reviewed

  
• Cobalt-dependent inhibition of nitrite oxidation in Nitrobacter winogradskyi.

  Richard Metzner; Taiji Nomura; Naoki Kitaoka; Akinori Ando; Jun Ogawa; Yasuo Kato

  Journal of bioscience and bioengineering, Oct. 2019, Peer-reviewed

  
• Cloning of a novel gene involved in alkane biosynthesis from Klebsiella sp

  Ito, M; H. Kambe; A. Sawagashira; S. Kishino; M. Takeuchi; A. Ando; M. Muramatsu; J. Ogawa

  Appl. Microbiol. Biotechnol., 2019, Peer-reviewed

  
• Effects of alkyl gallates, fatty acids, and acylglycerols on the growth of the psychrotolerant bacterium Sporosarcina sp. S92h

  Tsuda, K; H. Nagano; R. Nakatsuji; M. Takeuchi; A. Ando; J. Shima; J. Ogawa

  Biocatal Agric Biotechnol, Jan. 2019, Peer-reviewed

  
• 脂肪酸水和酵素の多様性と新規酵素の機能解明

  小川 順; 平田晶子; 竹内道樹; 岸野重信

  ビタミン, Nov. 2018

  
• Inhibitory effect of the gut microbial linoleic acid metabolites, 10-oxo-trans-11-octadecenoic acid and 10-hydroxy-cis-12-octadecenoic acid, on BV-2 microglial cell activation

  S. Ikeguchi; Y. Izumi; N. Kitamura; S. Kishino; J. Ogawa; A. Akaikea; T. Kume

  J. Pharmacol. Sci., Sep. 2018, Peer-reviewed

  
• Lipid production via simultaneous conversion of glucose and xylose by a novel yeast, Cystobasidium iriomotense

  Tanimura, A; T. Sugita; R. Endoh; M. Ohkuma; S. Kishino; J. Ogawa; J. Shima; M. Takashima

  PLOS ONE, Sep. 2018, Peer-reviewed

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• Novel mechanism of fatty acid sensing in enteroendocrine cells: Specific structures in oxo-fatty acids produced by gut bacteria are responsible for CCK secretion in STC-1 cells via GPR40

  T. Hira; S. Ogasawara; A. Yahagi; M. Kamachi; J. Li; S. Nishimura; M. Sakaino; T. Yamashita; S. Kishino; J. Ogawa; H. Hara

  Mol. Nutr. Food Res., Jun. 2018, Peer-reviewed

  
• A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling

  Yamada, M; N. Takahashi; Y. Matsuda; K. Sato; M. Yokoji; B. Sulijaya; T. Maekawa; T. Ushiki; Y. Mikami; M. Hayatsu; Y. Mizutani; S. Kishino; J. Ogawa; M. Arita; K. Tabeta; T. Maeda; K. Yamazaki

  Sci. Rep., Jun. 2018, Peer-reviewed

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• Arachidonic acid production by the oleaginous fungus Mortierella alpina 1S-4: A review

  Hiroshi Kikukawa; Eiji Sakuradani; Akinori Ando; Sakayu Shimizu; Jun Ogawa

  Journal of Advanced Research, 01 May 2018, Peer-reviewed

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• 中鎖脂肪酸トリグリセリドの経口摂取後の腸管吸収過程に関する検討

  村田 由貴; 原田 範雄; 岸野 重信; 金丸 良徳; 山根 俊介; 原田 貴成; 三小田 亜希子; 池口 絵理; 小川 順; 稲垣 暢哉

  糖尿病, Apr. 2018

  
• 脂肪酸受容体を介した腸内細菌代謝物の包括的なエネルギー代謝制御機構の解明

  宮本 潤基; 唐木 晋一郎; 岸野 重信; 入江 潤一郎; 菅原 達也; 杉本 幸彦; 有田 誠; 小川 順; 伊藤 裕; 木村 郁夫

  日本内分泌学会雑誌, Apr. 2018, Peer-reviewed

  
• 食事脂質による脂肪酸受容体を介したエネルギー代謝制御

  向山 広美; 宮本 潤基; 岸野 重信; 入江 潤一郎; 菅原 達也; 有田 誠; 小川 順; 伊藤 裕; 木村 郁夫

  腸内細菌学雑誌, Apr. 2018, Peer-reviewed

  
• The anti-inflammatory effect of 10-oxo-trans-11-octadecenoic acid (KetoC) on RAW 264.7 cells stimulated with Porphyromonas gingivalis lipopolysaccharide

  B. Sulijaya; N. Takahashi; M. Yamada; M. Yokoji; K. Sato; Y. Aoki-Nonaka; T. Nakajima; S. Kishino; J. Ogawa; K. Yamazaki

  J. Periodont. Res., Apr. 2018, Peer-reviewed

  
• Attempt to simultaneously generate three chiral centers in 4-hydroxyisoleucine with microbial carbonyl reductases

  Makoto Hibi; Koji Takahashi; Junko Kako; Yuuta Wakita; Tomohiro Kodera; Sakayu Shimizu; Kenzo Yokozeki; Jun Ogawa

  Bioorganic and Medicinal Chemistry, 01 Apr. 2018, Peer-reviewed

  
• 脂肪酸クオリティに影響を与える食事脂質の腸内細菌代謝と代謝産物の生理機能

  小川 順; 岸野重信

  医学のあゆみ, Mar. 2018, Peer-reviewed

  
• 腸内細菌が作る修飾脂肪酸について

  岸野重信; 小川 順

  化学工業, Mar. 2018, Peer-reviewed

  
• Hydratase, Dehydrogenase, Isomerase, and Enone Reductase Involved in Fatty Acid Saturation Metabolism.

  Ogawa, J; M. Takeuchi; S. Kishino

  Lipid Modification by Enzymes and Engineered Microbes, 2018, Peer-reviewed

  
• New nucleoside hydrolase with transribosylation activity from Agromyces sp. MM-1 and its application for enzymatic synthesis of 2′-O-methylribonucleosides

  Yuuki Mitsukawa; Makoto Hibi; Narihiro Matsutani; Nobuyuki Horinouchi; Satomi Takahashi; Jun Ogawa

  Journal of Bioscience and Bioengineering, 01 Jan. 2018, Peer-reviewed

  
• A search for microorganisms producing medium-chain alkanes from aldehydes

  Masakazu Ito; Hiromi Kambe; Shigenobu Kishino; Masayoshi Muramatsu; Jun Ogawa

  Journal of Bioscience and Bioengineering, 01 Jan. 2018, Peer-reviewed

  
• A-Linolenic acid–derived metabolites from gut lactic acid bacteria induce differentiation of anti-inflammatory M2 macrophages through G protein-coupled receptor 40

  Ryuji Ohue-Kitano; Yumiko Yasuoka; Tsuyoshi Goto; Nahoko Kitamura; Si-Bum Park; Shigenobu Kishino; Ikuo Kimura; Mayu Kasubuchi; Haruya Takahashi; Yongjia Li; Yu-Sheng Yeh; Huei-Fen Jheng; Mari Iwase; Masashi Tanaka; Shinya Masuda; Takayuki Inoue; Hajime Yamakage; Toru Kusakabe; Fumito Tani; Akira Shimatsu; Nobuyuki Takahashi; Jun Ogawa; Noriko Satoh-Asahara; Teruo Kawada

  FASEB Journal, 01 Jan. 2018, Peer-reviewed

  
• 健康をサポートするオメガ3脂肪酸をとどける、理解する、発信する

  小川 順

  JATAFFジャーナル, 2018, Peer-reviewed

  
• 腸内細菌が作る機能性脂肪酸「HYA」の効果

  米島靖記; 岸野重信; 小川 順

  アレルギーの臨床, 2018, Peer-reviewed

  
• Electrochemical Study on the Extracellular Electron Transfer Pathway from Shewanella Strain Hac319 to Electrodes

  Ryosuke Takeuchi; Yu Sugimoto; Yuki Kitazumi; Osamu Shirai; Jun Ogawa; Kenji Kano

  ANALYTICAL SCIENCES, Oct. 2018, Peer-reviewed

  
• Metabolic engineering of oleaginous fungus Mortierella alpina for high production of oleic and linoleic acids

  Takaiku Sakamoto; Eiji Sakuradani; Tomoyo Okuda; Hiroshi Kikukawa; Akinori Ando; Shigenobu Kishino; Yoshihiro Izumi; Takeshi Bamba; Jun Shima; Jun Ogawa

  BIORESOURCE TECHNOLOGY, Dec. 2017, Peer-reviewed

  
• 10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, enhances energy metabolism by activation of TRPV1

  Minji Kim; Tomoya Furuzono; Kanae Yamakuni; Yongjia Li; Young-Il Kim; Haruya Takahashi; Ryuji Ohue-Kitano; Huei-Fen Jheng; Nobuyuki Takahashi; Yuriko Kano; Rina Yu; Shigenobu Kishino; Jun Ogawa; Kunitoshi Uchida; Jun Yamazaki; Makoto Tominaga; Teruo Kawada; Tsuyoshi Goto

  FASEB JOURNAL, Nov. 2017, Peer-reviewed

  
• 腸内細菌が作る機能性脂肪酸「HYA」の効果

  米島靖記; 岸野重信; 小川 順

  アレルギーの臨床, Nov. 2017, Peer-reviewed

  
• Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S, 3R, 4S)-4-hydroxyisoleucine with three asymmetric centers

  Xuan Shi; Takuya Miyakawa; Akira Nakamura; Feng Hou; Makoto Hibi; Jun Ogawa; Yeondae Kwon; Masaru Tanokura

  SCIENTIFIC REPORTS, Oct. 2017, Peer-reviewed

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• Synthesized enone fatty acids resembling metabolites from gut microbiota suppress macrophage-mediated inflammation in adipocytes

  Ha-Eun Yang; Yongjia Li; Akira Nishimura; Huei-Fen Jheng; Ana Yuliana; Ryuji Kitano-Ohue; Wataru Nomura; Nobuyuki Takahashi; Chu-Sook Kim; Rina Yu; Nahoko Kitamura; Si-Bum Park; Shigenobu Kishino; Jun Ogawa; Teruo Kawada; Tsuyoshi Goto

  MOLECULAR NUTRITION & FOOD RESEARCH, Oct. 2017, Peer-reviewed

  
• Engineering of the cytochrome P450 monooxygenase system for benzyl maltol hydroxylation

  Iori Kozono; Kousuke Mihara; Kazuyuki Minagawa; Makoto Hibi; Jun Ogawa

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Sep. 2017, Peer-reviewed

  
• 乳酸菌に特異な脂肪酸代謝と代謝産物の生理機能について

  岸野重信; 小川 順

  日本乳酸菌学会誌, Jun. 2017

  
• 特集腸内細菌?糖尿病・肥満にまつわる10 topics ?各論?トピック10?PPARα活性化による食後高脂血症改善作用と腸内細菌叢

  高橋信之; 上原万里子; 岸野重信; 小川 順; 河田照雄

  糖尿病診療マスター, Jun. 2017

  
• Modulation of fatty acid composition and growth in Sporosarcina species in response to temperatures and exogenous branched-chain amino acids

  Kentaro Tsuda; Hideaki Nagano; Akinori Ando; Jun Shima; Jun Ogawa

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Jun. 2017, Peer-reviewed

  
• 特集腸内細菌 -糖尿病・肥満にまつわる10 topics Ⅱ各論 -トピック10- PPARα活性化による食後高脂血症改善作用と腸内細菌叢.

  高橋信之; 上原万里子; 岸野重信; 小川 順; 河田照雄

  糖尿病診療マスター, Jun. 2017

  
• Enzymatic synthesis of 2 '-O-methylribonucleosides with a nucleoside hydrolase family enzyme from Lactobacillus buchneri LBK78

  Yuuki Mitsukawa; Makoto Hibi; Narihiro Matsutani; Nobuyuki Horinouchi; Satomi Takahashi; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Jun. 2017, Peer-reviewed

  
• Bioconversion of Castor Oil by Microorganisms

  Takenaka, R; S. Morita; M. Kise; Y. Mitsukawa; M. Takeuchi; J. Ogawa

  ELCAS Journal, Mar. 2017, Peer-reviewed

  
• Supplemental feeding of a gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, alleviates spontaneous atopic dermatitis and modulates intestinal microbiota in NC/nga mice

  Hiroko Kaikiri; Junki Miyamoto; Takahiro Kawakami; Si-Bum Park; Nahoko Kitamura; Shigenobu Kishino; Yasunori Yonejima; Keiko Hisa; Jun Watanabe; Tasuku Ogita; Jun Ogawa; Soichi Tanabe; Takuya Suzuki

  INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, 2017, Peer-reviewed

  
• Microbial Synthesis of Oxo Cyclic Amino Acids

  Kise, M; S. Morita; R. Takenaka; Y. Mitsukawa; M. Takeuchi; J. Ogawa

  ELCAS Journal, 2017, Peer-reviewed

  
• Microbial Decarboxylation of Dicarboxylic Acid Monomethyl Ester

  Morita, S; M. Kise; R. Takenaka; Y. Mitsukawa; M. Takeuchi; J. Ogawa

  ELCAS Journal, 2017, Peer-reviewed

  
• 総説・腸内細菌と栄養代謝

  小川 順; 岸野重信

  栄養 Trends of Nutrition, 2017, Peer-reviewed

  
• Draft genome sequences of the xylose-fermenting yeast Scheffersomyces shehatae NBRC 1983T and a thermotolerant isolate of S. shehatae ATY839 (JCM 18690)

  Natsumi Okada; Ayumi Tanimura; Hideki Hirakawa; Masako Takashima; Jun Ogawa; Jun Shima

  Genome Announcements, 2017, Peer-reviewed

  
• でん粉からバイオ燃料を作る

  谷村あゆみ; 岸野重信; 小川 順; 島 純

  月報 砂糖類・でん粉情報, Jan. 2017

  
• Production of ricinoleic acid-containing monoestolide triacylglycerides in an oleaginous diatom, Chaetoceros gracilis

  Masataka Kajikawa; Tatsuki Abe; Kentaro Ifuku; Ken-ichi Furutani; Dongyi Yan; Tomoyo Okuda; Akinori Ando; Shigenobu Kishino; Jun Ogawa; Hideya Fukuzawa

  SCIENTIFIC REPORTS, Nov. 2016, Peer-reviewed

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• Production of ricinoleic acid-containing monoestolide triacylglycerides in an oleaginous diatom, Chaetoceros gracilis

  Masataka Kajikawa; Tatsuki Abe; Kentaro Ifuku; Ken-ichi Furutani; Dongyi Yan; Tomoyo Okuda; Akinori Ando; Shigenobu Kishino; Jun Ogawa; Hideya Fukuzawa

  SCIENTIFIC REPORTS, Nov. 2016, Peer-reviewed

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• Production of ricinoleic acid-containing monoestolide triacylglycerides in an oleaginous diatom, Chaetoceros gracilis

  Masataka Kajikawa; Tatsuki Abe; Kentaro Ifuku; Ken-ichi Furutani; Dongyi Yan; Tomoyo Okuda; Akinori Ando; Shigenobu Kishino; Jun Ogawa; Hideya Fukuzawa

  SCIENTIFIC REPORTS, Nov. 2016, Peer-reviewed

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• Essential fatty acids for oleaginous fungus Mortierella alpina

  Tomohiro Fujita; Hiroshi Kawashima; Eiji Sakuradani; Takaiku Sakamoto; Akinori Ando; Jun Ogawa; Sakayu Shimizu

  Biocatalysis and Agricultural Biotechnology, 01 Oct. 2016, Peer-reviewed

  
• Lipid production through simultaneous utilization of glucose, xylose, and l-arabinose by Pseudozyma hubeiensis: a comparative screening study

  Ayumi Tanimura; Masako Takashima; Takashi Sugita; Rikiya Endoh; Moriya Ohkuma; Shigenobu Kishino; Jun Ogawa; Jun Shima

  AMB EXPRESS, Aug. 2016, Peer-reviewed

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• A novel nucleoside hydrolase from Lactobacillus buchneri LBK78 catalyzing hydrolysis of 2 '-O-methylribonucleosides

  Yuuki Mitsukawa; Makoto Hibi; Narihiro Matsutani; Nobuyuki Horinouchi; Satomi Takahashi; Jun Ogawa

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Aug. 2016, Peer-reviewed

  
• Lipid production through simultaneous utilization of glucose, xylose, and l-arabinose by Pseudozyma hubeiensis: a comparative screening study

  Ayumi Tanimura; Masako Takashima; Takashi Sugita; Rikiya Endoh; Moriya Ohkuma; Shigenobu Kishino; Jun Ogawa; Jun Shima

  AMB EXPRESS, Aug. 2016, Peer-reviewed

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• Lipid production through simultaneous utilization of glucose, xylose, and l-arabinose by Pseudozyma hubeiensis: a comparative screening study

  Ayumi Tanimura; Masako Takashima; Takashi Sugita; Rikiya Endoh; Moriya Ohkuma; Shigenobu Kishino; Jun Ogawa; Jun Shima

  AMB EXPRESS, Aug. 2016, Peer-reviewed

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• Microbial production of dihomo-gamma-linolenic acid by Delta 5-desaturase gene-disruptants of Mortierella alpina 1S-4

  Hiroshi Kikukawa; Eiji Sakuradani; Akinori Ando; Tomoyo Okuda; Sakayu Shimizu; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Jul. 2016, Peer-reviewed

  
• 腸内細菌が作る機能性脂肪酸「HYA」の効果

  米嶋靖記; 岸野重信; 小川 順

  メディカル・サイエンス・ダイジェスト, Jun. 2016, Peer-reviewed

  
• Biocatalytic Introduction of Chiral Hydroxy Groups using Oxygenases and Hydratases

  Jun Ogawa; Makoto Hibi; Shigenobu Kishino

  Green Biocatalysis, 13 May 2016

  
• Efficient enzymatic production of hydroxy fatty acids by linoleic acid 9 hydratase from Lactobacillus plantarum AKU 1009a

  M. Takeuchi; S. Kishino; S. -B. Park; A. Hirata; N. Kitamura; A. Saika; J. Ogawa

  JOURNAL OF APPLIED MICROBIOLOGY, May 2016, Peer-reviewed

  
• Characterization of starch-accumulating duckweeds, Wolffia globosa, as renewable carbon source for bioethanol production

  Tomohiro Fujita; Eiji Nakao; Michiki Takeuchi; Ayumi Tanimura; Akinori Ando; Shigenobu Kishino; Hiroshi Kikukawa; Jun Shima; Jun Ogawa; Sakayu Shimizu

  Biocatalysis and Agricultural Biotechnology, 01 Apr. 2016, Peer-reviewed

  
• 10-Oxo-trans-11-octadecenoic acid generated from linoleic acid by a gut lactic acid bacterium Lactobacillus plantarum is cytoprotective against oxidative stress

  Hidehiro Furumoto; Tharnath Nanthirudjanar; Toshiaki Kume; Yasuhiko Izumi; Si-Bum Park; Nahoko Kitamura; Shigenobu Kishino; Jun Ogawa; Takashi Hirata; Tatsuya Sugawara

  TOXICOLOGY AND APPLIED PHARMACOLOGY, Apr. 2016, Peer-reviewed

  
• Novel Enzyme Family Found in Filamentous Fungi Catalyzing trans-4-Hydroxylation of L-Pipecolic Acid

  Makoto Hibi; Ryosuke Mori; Ryoma Miyake; Hiroshi Kawabata; Shoko Kozono; Satomi Takahashi; Jun Ogawa

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Apr. 2016, Peer-reviewed

  
• 10-Oxo-trans-11-octadecenoic acid generated from linoleic acid by a gut lactic acid bacterium Lactobacillus plantarum is cytoprotective against oxidative stress

  Hidehiro Furumoto; Tharnath Nanthirudjanar; Toshiaki Kume; Yasuhiko Izumi; Si-Bum Park; Nahoko Kitamura; Shigenobu Kishino; Jun Ogawa; Takashi Hirata; Tatsuya Sugawara

  TOXICOLOGY AND APPLIED PHARMACOLOGY, Apr. 2016, Peer-reviewed

  
• Characterization of starch-accumulating duckweeds, Wolffia globosa, as renewable carbon source for bioethanol production

  Tomohiro Fujita; Eiji Nakao; Michiki Takeuchi; Ayumi Tanimura; Akinori Ando; Shigenobu Kishino; Hiroshi Kikukawa; Jun Shima; Jun Ogawa; Sakayu Shimizu

  Biocatalysis and Agricultural Biotechnology, 01 Apr. 2016, Peer-reviewed

  
• 腸内細菌の脂肪酸代謝と代謝産物の生理機能

  小川 順; 岸野重信

  The Lipid, Apr. 2016, Peer-reviewed

  
• Efficient enzymatic production of hydroxy fatty acids by linoleic acid 9 hydratase from Lactobacillus plantarum AKU 1009a

  M. Takeuchi; S. Kishino; S. -B. Park; A. Hirata; N. Kitamura; A. Saika; J. Ogawa

  JOURNAL OF APPLIED MICROBIOLOGY, May 2016, Peer-reviewed

  
• Production of dicarboxylic acids from novel unsaturated fatty acids by laccase-catalyzed oxidative cleavage

  Michiki Takeuchi; Shigenobu Kishino; Si-Bum Park; Nahoko Kitamura; Hiroko Watanabe; Azusa Saika; Makoto Hibi; Kenzo Yokozeki; Jun Ogawa

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2016, Peer-reviewed

  
• 糸状菌に由来する新規ステロイド11β水酸化酵素の同定

  日比 慎; 木村隆利; 小川 順

  バイオサイエンスとインダストリー, 2016, Peer-reviewed

  
• アミノ酸水酸化酵素を例にした酵素触媒の多様化への試み

  日比 慎; 小川 順

  科学と工業, 2016, Peer-reviewed

  
• 脂質バランス栄養食品を創出する新規オメガ3脂肪酸素材の開発

  OGAWA Jun

  JATAFFジャーナル, 2016, Peer-reviewed

  
• 廃棄されるデンプン系バイオマスの有効利用に向けた酵母の機能探索. バイオサイエンスとインダストリー

  島 純; 谷村あゆみ; 小川 順

  バイオサイエンスとインダストリー, 2016, Peer-reviewed

  
• 長鎖不飽和脂肪酸とその腸内細菌代謝物によるGPR120活性化の検討

  本郷翔子; 森本育美; 山上小百合; 古田美咲; 滝澤祥恵; 井上飛鳥; 青木淳賢; 東山繁樹; 吉田守克; 宮里幹也; 岸野重信; 小川 順; 中田理恵子; 井上裕康

  脂質生化学研究, 2016, Peer-reviewed

  
• Analysis of microbial community and nitrogen transition with enriched nitrifying soil microbes for organic hydroponics

  Sakuntala Saijai; Akinori Ando; Ryuya Inukai; Makoto Shinohara; Jun Ogawa

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2016, Peer-reviewed

  
• Production of dicarboxylic acids from novel unsaturated fatty acids by laccase-catalyzed oxidative cleavage

  Michiki Takeuchi; Shigenobu Kishino; Si-Bum Park; Nahoko Kitamura; Hiroko Watanabe; Azusa Saika; Makoto Hibi; Kenzo Yokozeki; Jun Ogawa

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2016, Peer-reviewed

  
• Imidase catalyzing desymmetric imide hydrolysis forming optically active 3-substituted glutaric acid monoamides for the synthesis of gamma-aminobutyric acid (GABA) analogs

  Masutoshi Nojiri; Makoto Hibi; Hiroaki Shizawa; Nobuyuki Horinouchi; Yoshihiko Yasohara; Satomi Takahashi; Jun Ogawa

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Dec. 2015, Peer-reviewed

  
• Eicosapentaenoic acid (EPA) production by an oleaginous fungus Mortierella alpina expressing heterologous the Delta 17-desaturase gene under ordinary temperature

  Tomoyo Okuda; Akinori Ando; Hiroaki Negoro; Tatsuya Muratsubaki; Hiroshi Kikukawa; Takaiku Sakamoto; Eiji Sakuradani; Sakayu Shimizu; Jun Ogawa

  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Dec. 2015, Peer-reviewed

  
• Gut Microbial Fatty Acid Metabolites Reduce Triacylglycerol Levels in Hepatocytes

  Tharnath Nanthirudjanar; Hidehiro Furumoto; Jiawen Zheng; Young-Il Kim; Tsuyoshi Goto; Nobuyuki Takahashi; Teruo Kawada; Si-Bum Park; Akiko Hirata; Nahoko Kitamura; Shigenobu Kishino; Jun Ogawa; Takashi Hirata; Tatsuya Sugawara

  LIPIDS, Nov. 2015, Peer-reviewed

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• Gene targeting in the oil-producing fungus Mortierella alpina 1S-4 and construction of a strain producing a valuable polyunsaturated fatty acid

  Hiroshi Kikukawa; Eiji Sakuradani; Masato Nakatani; Akinori Ando; Tomoyo Okuda; Takaiku Sakamoto; Misa Ochiai; Sakayu Shimizu; Jun Ogawa

  CURRENT GENETICS, Nov. 2015, Peer-reviewed

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• Gut Microbial Fatty Acid Metabolites Reduce Triacylglycerol Levels in Hepatocytes

  Tharnath Nanthirudjanar; Hidehiro Furumoto; Jiawen Zheng; Young-Il Kim; Tsuyoshi Goto; Nobuyuki Takahashi; Teruo Kawada; Si-Bum Park; Akiko Hirata; Nahoko Kitamura; Shigenobu Kishino; Jun Ogawa; Takashi Hirata; Tatsuya Sugawara

  LIPIDS, Nov. 2015, Peer-reviewed

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• Lactic acid bacteria-containing chocolate as a practical probiotic product with increased acid tolerance

  Yasunori Yonejima; Keiko Hisa; Marina Kawaguchi; Hiroaki Ashitani; Toshiyuki Koyama; Yoko Usamikrank; Nayumi Kishida; Shigenobu Kishino; Jun Ogawa

  Biocatalysis and Agricultural Biotechnology, 01 Oct. 2015, Peer-reviewed

  
• Neurite outgrowth stimulation by n-3 and n-6 PUFAs of phospholipids in apoE-containing lipoproteins secreted from glial cells

  Mitsuhiro Nakato; Michinori Matsuo; Nozomu Kono; Makoto Arita; Hiroyuki Arai; Jun Ogawa; Noriyuki Kioka; Kazumitsu Ueda

  JOURNAL OF LIPID RESEARCH, Oct. 2015, Peer-reviewed

  
• Lactic acid bacteria-containing chocolate as a practical probiotic product with increased acid tolerance

  Yasunori Yonejima; Keiko Hisa; Marina Kawaguchi; Hiroaki Ashitani; Toshiyuki Koyama; Yoko Usamikrank; Nayumi Kishida; Shigenobu Kishino; Jun Ogawa

  Biocatalysis and Agricultural Biotechnology, 01 Oct. 2015, Peer-reviewed

  
• Omega-3 eicosatetraenoic acid production by molecular breeding of the mutant strain S14 derived from Mortierella alpina 1S-4

  Tomoyo Okuda; Akinori Ando; Hiroaki Negoro; Hiroshi Kikukawa; Takaiku Sakamoto; Eiji Sakuradani; Sakayu Shimizu; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Sep. 2015, Peer-reviewed

  
• Disruption of lig4 improves gene targeting efficiency in the oleaginous fungus Mortierella alpina 1S-4

  Hiroshi Kikukawa; Eiji Sakuradani; Akinori Ando; Tomoyo Okuda; Misa Ochiai; Sakayu Shimizu; Jun Ogawa

  JOURNAL OF BIOTECHNOLOGY, Aug. 2015, Peer-reviewed

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• A novel unsaturated fatty acid hydratase toward C16 to C22 fatty acids from Lactobacillus acidophilus

  Akiko Hirata; Shigenobu Kishino; Si-Bum Park; Michiki Takeuchi; Nahoko Kitamura; Jun Ogawa

  JOURNAL OF LIPID RESEARCH, Jul. 2015, Peer-reviewed

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• A novel unsaturated fatty acid hydratase toward C16 to C22 fatty acids from Lactobacillus acidophilus

  Akiko Hirata; Shigenobu Kishino; Si-Bum Park; Michiki Takeuchi; Nahoko Kitamura; Jun Ogawa

  JOURNAL OF LIPID RESEARCH, Jul. 2015, Peer-reviewed

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• Characterization of hydroxy fatty acid dehydrogenase involved in polyunsaturated fatty acid saturation metabolism in Lactobacillus plantarum AKU 1009a

  Michiki Takeuchi; Shigenobu Kishino; Si-Bum Park; Nahoko Kitamura; Jun Ogawa

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Jul. 2015, Peer-reviewed

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• Characterization of the linoleic acid Delta 9 hydratase catalyzing the first step of polyunsaturated fatty acid saturation metabolism in Lactobacillus plantarum AKU 1009a

  Michiki Takeuchi; Shigenobu Kishino; Akiko Hirata; Si-Bum Park; Nahoko Kitamura; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Jun. 2015, Peer-reviewed

  
• Characterization of the linoleic acid Delta 9 hydratase catalyzing the first step of polyunsaturated fatty acid saturation metabolism in Lactobacillus plantarum AKU 1009a

  Michiki Takeuchi; Shigenobu Kishino; Akiko Hirata; Si-Bum Park; Nahoko Kitamura; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Jun. 2015, Peer-reviewed

  
• New lipid science in our inner ecosystem

  Jun Ogawa

  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, May 2015, Peer-reviewed

  
• Structure and reaction mechanism of a novel enone reductase

  Feng Hou; Takuya Miyakawa; Nahoko Kitamura; Michiki Takeuchi; Si-Bum Park; Shigenobu Kishino; Jun Ogawa; Masaru Tanokura

  FEBS JOURNAL, Apr. 2015, Peer-reviewed

  
• 10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPAR gamma and stimulates adipogenesis

  Tsuyoshi Goto; Young-Il Kim; Tomoya Furuzono; Nobuyuki Takahashi; Kanae Yamakuni; Ha-Eun Yang; Yongjia Li; Ryuji Ohue; Wataru Nomura; Tatsuya Sugawara; Rina Yu; Nahoko Kitamura; Si-Bum Park; Shigenobu Kishino; Jun Ogawa; Teruo Kawada

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2015, Peer-reviewed

  
• Direct ethanol production from starch using a natural isolate, Scheffersomyces shehatae: Toward consolidated bioprocessing

  Ayumi Tanimura; Minako Kikukawa; Shino Yamaguchi; Shigenobu Kishino; Jun Ogawa; Jun Shima

  SCIENTIFIC REPORTS, Apr. 2015, Peer-reviewed

  
• A new aldehyde oxidase catalyzing the conversion of glycolaldehyde to glycolate from Burkholderia sp AIU 129

  Miwa Yamada; Keika Adachi; Natsumi Ogawa; Shigenobu Kishino; Jun Ogawa; Michihiko Kataoka; Sakayu Shimizu; Kimiyasu Isobe

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Apr. 2015, Peer-reviewed

  
• Structure and reaction mechanism of a novel enone reductase

  Feng Hou; Takuya Miyakawa; Nahoko Kitamura; Michiki Takeuchi; Si-Bum Park; Shigenobu Kishino; Jun Ogawa; Masaru Tanokura

  FEBS JOURNAL, Apr. 2015, Peer-reviewed

  
• Direct ethanol production from starch using a natural isolate, Scheffersomyces shehatae: Toward consolidated bioprocessing

  Ayumi Tanimura; Minako Kikukawa; Shino Yamaguchi; Shigenobu Kishino; Jun Ogawa; Jun Shima

  SCIENTIFIC REPORTS, Apr. 2015, Peer-reviewed

  
• A new aldehyde oxidase catalyzing the conversion of glycolaldehyde to glycolate from Burkholderia sp AIU 129

  Miwa Yamada; Keika Adachi; Natsumi Ogawa; Shigenobu Kishino; Jun Ogawa; Michihiko Kataoka; Sakayu Shimizu; Kimiyasu Isobe

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Apr. 2015, Peer-reviewed

  
• Isolation and characterization of psychrotolerant endospore-forming Sporosarcina species associated with minced fish meat (surimi)

  Kentaro Tsuda; Hideaki Nagano; Akinori Ando; Jun Shima; Jun Ogawa

  INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, Apr. 2015, Peer-reviewed

  
• 10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPAR gamma and stimulates adipogenesis

  Tsuyoshi Goto; Young-Il Kim; Tomoya Furuzono; Nobuyuki Takahashi; Kanae Yamakuni; Ha-Eun Yang; Yongjia Li; Ryuji Ohue; Wataru Nomura; Tatsuya Sugawara; Rina Yu; Nahoko Kitamura; Si-Bum Park; Shigenobu Kishino; Jun Ogawa; Teruo Kawada

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 2015, Peer-reviewed

  
• Production of cis-11-eicosenoic acid by Mortierella fungi

  H. Kikukawa; E. Sakuradani; Y. Nishibaba; T. Okuda; A. Ando; J. Shima; S. Shimizu; J. Ogawa

  JOURNAL OF APPLIED MICROBIOLOGY, Mar. 2015, Peer-reviewed

  
• Multi-Enzymatic Synthesis of Optically Pure beta-Hydroxy alpha-Amino Acids

  Makoto Hibi; Takuya Kasahara; Takashi Kawashima; Hiroko Yajima; Shoko Kozono; Sergey V. Smirnov; Tomohiro Kodera; Masakazu Sugiyama; Sakayu Shimizu; Kenzo Yokozeki; Jun Ogawa

  ADVANCED SYNTHESIS & CATALYSIS, Mar. 2015, Peer-reviewed

  
• Trehalose accumulation enhances tolerance of Saccharomyces cerevisiae to acetic acid

  Yoko Yoshiyama; Koichi Tanaka; Kohei Yoshiyama; Makoto Hibi; Jun Ogawa; Jun Shima

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Feb. 2015, Peer-reviewed

  
• 1. 不飽和脂肪酸飽和化代謝の初発酵素リノール酸水和酵素の諸性質解明と応用(第439回研究協議会研究発表要旨,ビタミンB研究委員会)

  小川 順; 竹内 道樹; 岸野 重信

  ビタミン, 2015

  
• A Gut Microbial Metabolite of Linoleic Acid, 10-Hydroxy-cis-12-octadecenoic Acid, Ameliorates Intestinal Epithelial Barrier Impairment Partially via GPR40-MEK-ERK Pathway

  Junki Miyamoto; Taichi Mizukure; Si-Bum Park; Shigenobu Kishino; Ikuo Kimura; Kanako Hirano; Paolo Bergamo; Mauro Rossi; Takuya Suzuki; Makoto Arita; Jun Ogawa; Soichi Tanabe

  JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 2015, Peer-reviewed

  
• 有機酸ストレス耐性機構の解明と新規バイオ燃料生産プロセスの構築

  島 純; 田中晃一; 安藤晃規; 小川 順

  IFO Res. Commun., 2015

  
• A Gut Microbial Metabolite of Linoleic Acid, 10-Hydroxy-cis-12-octadecenoic Acid, Ameliorates Intestinal Epithelial Barrier Impairment Partially via GPR40-MEK-ERK Pathway

  Junki Miyamoto; Taichi Mizukure; Si-Bum Park; Shigenobu Kishino; Ikuo Kimura; Kanako Hirano; Paolo Bergamo; Mauro Rossi; Takuya Suzuki; Makoto Arita; Jun Ogawa; Soichi Tanabe

  JOURNAL OF BIOLOGICAL CHEMISTRY, Jan. 2015, Peer-reviewed

  
• A Consolidated Bioprocessing of Biofuels from Non-food Starchy Biomass by Yeast

  谷村あゆみ; 小川 順; 島 純

  BIOINDUSTRY, 2015

  
• 新規アミノ酸水酸化酵素群の機能解析と生理活性アミノ酸合成への応用

  小川 順

  日本応用酵素協会誌, 2015

  
• 藻類に託されるグリーンビジネス成長戦略 のゆくえ

  小川 順

  バイオサイエンスとインダストリー, 2015

  
• 食事脂質の腸内細菌代謝と代謝産物の生理機能

  小川 順; 岸野重信

  消化と吸収, 2015

  
• The Case for an Early Biological Origin of DNA

  Anthony M. Poole; Nobuyuki Horinouchi; Ryan J. Catchpole; Dayong Si; Makoto Hibi; Koichi Tanaka; Jun Ogawa

  JOURNAL OF MOLECULAR EVOLUTION, Dec. 2014, Peer-reviewed

  
• Immunomodulatory activity of a gut microbial metabolite of dietary linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, associated with improved antioxidant/detoxifying defences

  Paolo Bergamo; Diomira Luongo; Junki Miyamoto; Ennio Cocca; Shigenobu Kishino; Jun Ogawa; Soichi Tanabe; Mauro Rossi

  JOURNAL OF FUNCTIONAL FOODS, Nov. 2014, Peer-reviewed

  
• Immunomodulatory activity of a gut microbial metabolite of dietary linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, associated with improved antioxidant/detoxifying defences

  Paolo Bergamo; Diomira Luongo; Junki Miyamoto; Ennio Cocca; Shigenobu Kishino; Jun Ogawa; Soichi Tanabe; Mauro Rossi

  JOURNAL OF FUNCTIONAL FOODS, Nov. 2014, Peer-reviewed

  
• Transformation of zygomycete Mortierella alpina using biolistic particle bombardment

  Eiji Sakuradani; Hiroshi Kikukawa; Seiki Takeno; Akinori Ando; Sakayu Shimizu; Jun Ogawa

  Genetic Transformation Systems in Fungi., 09 Oct. 2014, Peer-reviewed

  
• Production of a pharmaceutical intermediate via biohydroxylation using whole cells of Rhodococcus rubropertinctus N82

  Takatoshi Kimura; Chihiro Ishikawa; Antonio Osorio-Lozada; Karen T. Robins; Makoto Hibi; Jun Ogawa

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Oct. 2014, Peer-reviewed

  
• Biohydrogenation of C-20 polyunsaturated fatty acids by anaerobic bacteria

  Haruko Sakurama; Shigenobu Kishino; Kousuke Mihara; Akinori Ando; Keiko Kita; Satomi Takahashi; Sakayu Shimizu; Jun Ogawa

  JOURNAL OF LIPID RESEARCH, Sep. 2014, Peer-reviewed

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• Biohydrogenation of C-20 polyunsaturated fatty acids by anaerobic bacteria

  Haruko Sakurama; Shigenobu Kishino; Kousuke Mihara; Akinori Ando; Keiko Kita; Satomi Takahashi; Sakayu Shimizu; Jun Ogawa

  JOURNAL OF LIPID RESEARCH, Sep. 2014, Peer-reviewed

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• Structural optimization of SadA, an Fe(II)- and alpha-ketoglutarate-dependent dioxygenase targeting biocatalytic synthesis of N-succinyl-L-threo-3, 4-dimethoxyphenylserine

  Hui-Min Qin; Takuya Miyakawa; Akira Nakamura; Makoto Hibi; Jun Ogawa; Masaru Tanokura

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Aug. 2014, Peer-reviewed

  
• Selection and characterization of promoters based on genomic approach for the molecular breeding of oleaginous fungus Mortierella alpina 1S-4

  Tomoyo Okuda; Akinori Ando; Eiji Sakuradani; Hiroshi Kikukawa; Nozomu Kamada; Misa Ochiai; Jun Shima; Jun Ogawa

  CURRENT GENETICS, Aug. 2014, Peer-reviewed

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• Characterization of galactose-dependent promoters from an oleaginous fungus Mortierella alpina 1S-4

  Tomoyo Okuda; Akinori Ando; Eiji Sakuradani; Hiroshi Kikukawa; Nozomu Kamada; Misa Ochiai; Jun Shima; Jun Ogawa

  CURRENT GENETICS, Aug. 2014, Peer-reviewed

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• Novel alcohol oxidase with glycolate oxidase activity from Ochrobactrum sp AIU 033

  Miwa Yamada; Takanori Higashiyama; Shigenobu Kishino; Michihiko Kataoka; Jun Ogawa; Sakayu Shimizu; Kimiyasu Isobe

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Jul. 2014, Peer-reviewed

  
• Novel alcohol oxidase with glycolate oxidase activity from Ochrobactrum sp AIU 033

  Miwa Yamada; Takanori Higashiyama; Shigenobu Kishino; Michihiko Kataoka; Jun Ogawa; Sakayu Shimizu; Kimiyasu Isobe

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Jul. 2014, Peer-reviewed

  
• Characterization of a novel L-amino acid oxidase with protein oxidizing activity from Penicillium steckii AIU 027

  Kimiyasu Isobe; Ryota Taira; Youko Hoshi; Sou Matsuda; Miwa Yamada; Makoto Hibi; Shigenobu Kishino; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Jun. 2014, Peer-reviewed

  
• Characterization of a novel L-amino acid oxidase with protein oxidizing activity from Penicillium steckii AIU 027

  Kimiyasu Isobe; Ryota Taira; Youko Hoshi; Sou Matsuda; Miwa Yamada; Makoto Hibi; Shigenobu Kishino; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Jun. 2014, Peer-reviewed

  
• beta-Glucuronidase from Lactobacillus brevis useful for baicalin hydrolysis belongs to glycoside hydrolase family 30

  Haruko Sakurama; Shigenobu Kishino; Yoshie Uchibori; Yasunori Yonejima; Hisashi Ashida; Keiko Kita; Satomi Takahashi; Jun Ogawa

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, May 2014, Peer-reviewed

  
• beta-Glucuronidase from Lactobacillus brevis useful for baicalin hydrolysis belongs to glycoside hydrolase family 30

  Haruko Sakurama; Shigenobu Kishino; Yoshie Uchibori; Yasunori Yonejima; Hisashi Ashida; Keiko Kita; Satomi Takahashi; Jun Ogawa

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, May 2014, Peer-reviewed

  
• Comprehensive analysis of genes involved in the oxidative stress tolerance using yeast heterozygous deletion collection

  Natsumi Okada; Jun Ogawa; Jun Shima

  FEMS YEAST RESEARCH, May 2014, Peer-reviewed

  
• Characteristics and biotechnology applications of aliphatic amino acid hydroxylases belonging to the Fe(II)/alpha-ketoglutarate-dependent dioxygenase superfamily

  Makoto Hibi; Jun Ogawa

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, May 2014, Peer-reviewed

  
• beta-Glucuronidase from Lactobacillus brevis useful for baicalin hydrolysis belongs to glycoside hydrolase family 30

  Haruko Sakurama; Shigenobu Kishino; Yoshie Uchibori; Yasunori Yonejima; Hisashi Ashida; Keiko Kita; Satomi Takahashi; Jun Ogawa

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, May 2014, Peer-reviewed

  
• Cryptococcus terricola is a promising oleaginous yeast for biodiesel production from starch through consolidated bioprocessing

  Ayumi Tanimura; Masako Takashima; Takashi Sugita; Rikiya Endoh; Minako Kikukawa; Shino Yamaguchi; Eiji Sakuradani; Jun Ogawa; Moriya Ohkuma; Jun Shima

  SCIENTIFIC REPORTS, Apr. 2014, Peer-reviewed

  
• Achlorophyllous alga Prototheca zopfii oxidizes n-alkanes with different carbon-chain lengths through a unique subterminal oxidation pathway

  Yasushi Takimura; Eiji Sakuradani; Yusuke Natsume; Takashi Miyake; Jun Ogawa; Sakayu Shimizu

  Journal of Bioscience and Bioengineering, Mar. 2014, Peer-reviewed

  
• Achlorophyllous alga Prototheca zopfii oxidizes n-alkanes with different carbon-chain lengths through a unique subterminal oxidation pathway

  Yasushi Takimura; Eiji Sakuradani; Yusuke Natsume; Takashi Miyake; Jun Ogawa; Sakayu Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Mar. 2014, Peer-reviewed

  
• Selection of oleaginous yeasts with high lipid productivity for practical biodiesel production

  Ayumi Tanimura; Masako Takashima; Takashi Sugita; Rikiya Endoh; Minako Kikukawa; Shino Yamaguchi; Eiji Sakuradani; Jun Ogawa; Jun Shima

  BIORESOURCE TECHNOLOGY, Feb. 2014, Peer-reviewed

  
• Recent Advances in the Production of CLA and Conjugated Vegetable Oils: Microbial and Enzymatic Production of Conjugated Fatty Acids and Related Fatty Acids in Biohydrogenation Metabolism

  J. Ogawa; M. Takeuchi; S. Kishino

  Conjugated Linoleic Acids and Conjugated Vegetable Oils, CHAPTER 5, 2014, Peer-reviewed

  
• Selection of oleaginous yeasts with high lipid productivity for practical biodiesel production

  Ayumi Tanimura; Masako Takashima; Takashi Sugita; Rikiya Endoh; Minako Kikukawa; Shino Yamaguchi; Eiji Sakuradani; Jun Ogawa; Jun Shima

  Bioresource Technology, 2014, Peer-reviewed

  
• Characterization of galactose-dependent promoters from an oleaginous fungus Mortierella alpina 1S-4

  Tomoyo Okuda; Akinori Ando; Eiji Sakuradani; Hiroshi Kikukawa; Nozomu Kamada; Misa Ochiai; Jun Shima; Jun Ogawa

  Current Genetics, 2014, Peer-reviewed

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• Selection and characterization of promoters based on genomic approach for the molecular breeding of oleaginous fungus Mortierella alpina 1S-4

  Tomoyo Okuda; Akinori Ando; Eiji Sakuradani; Hiroshi Kikukawa; Nozomu Kamada; Misa Ochiai; Jun Shima; Jun Ogawa

  Current Genetics, 2014, Peer-reviewed

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• 腸内細菌脂質代謝研究を基盤とする新規機能性脂質の開発

  小川 順; 岸野重信

  オレオサイエンス, 2014

  
• 有機酸ストレス耐性機構の解明と新規バイオ燃料生産プロセスの構築

  島 純; 田中晃一; 安藤晃規; 小川 順

  Institute for Fermentation, Osaka. Research Communications, 2014, Peer-reviewed

  
• Improvement of a direct electron transfer-type fructose/dioxygen biofuel cell with a substrate-modified biocathode

  Keisei So; Shota Kawai; Yasuyuki Hamano; Yuki Kitazumi; Osamu Shirai; Makoto Hibi; Jun Ogawa; Kenji Kano

  PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2014, Peer-reviewed

  
• Improvement of a direct electron transfer-type fructose/dioxygen biofuel cell with a substrate-modified biocathode

  Keisei So; Shota Kawai; Yasuyuki Hamano; Yuki Kitazumi; Osamu Shirai; Makoto Hibi; Jun Ogawa; Kenji Kano

  PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2014, Peer-reviewed

  
• 酵母の環境ストレス耐性機構の解析と食品製造への応用

  島 純; 田中晃一; 安藤晃規; 小川 順

  IFO Res. Commun., 2014

  
• ノンコンベンショナル酵母の機能探索と油脂等の有用物質生産への応用

  島 純; 田中晃一; 安藤晃規; 小川 順

  IFO Res. Commun., 2014

  
• 有機栄養液栽培に寄与する微生物群の解析とその応用

  安藤晃規; 田中晃一; 島 純; 小川 順

  IFO Res. Commun., 2014

  
• シロイヌナズナの表層脂質アルカン生合成に関わる酵素群

  櫻谷英治; 小川 順

  バイオサイエンスとインダストリー, 2014

  
• 食事性脂質の腸内細菌代謝解析に基づく新規機能性脂質開発

  小川 順

  食品と開発, 2014

  
• 食事性脂質の腸内細菌代謝と代謝産物の生理機能-生命を支える脂質 最新の研究と臨床-

  小川 順

  医学の歩み, 2014

  
• Novel Functional Lipid Development Based on the Analysis of Gut Microbial Lipid Metabolism

  OGAWA Jun; KISHINO Shigenobu

  Oleoscience, 2014

  
• Characterization of a trifunctional fatty acid desaturase from oleaginous filamentous fungus Mortierella alpina 1S-4 using a yeast expression system

  Hiroshi Kikukawa; Eiji Sakuradani; Shigenobu Kishino; Si-Bum Park; Akinori Ando; Jun Shima; Misa Ochiai; Sakayu Shimizu; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Dec. 2013, Peer-reviewed

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• Characterization of a new enzyme oxidizing omega-amino group of aminocarboxyric acid, aminoalcohols and amines from Phialemonium sp AIU 274

  Kimiyasu Isobe; Tomoko Sasaki; Yuusuke Aigami; Miwa Yamada; Shigenobu Kishino; Jun Ogawa

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Dec. 2013, Peer-reviewed

  
• The rhizosphere microbial community in a multiple parallel mineralization system suppresses the pathogenic fungus Fusarium oxysporum

  Kazuki Fujiwara; Yuichiro Iida; Takashi Iwai; Chihiro Aoyama; Ryuya Inukai; Akinori Ando; Jun Ogawa; Jun Ohnishi; Fumihiro Terami; Masao Takano; Makoto Shinohara

  MICROBIOLOGYOPEN, Dec. 2013, Peer-reviewed

  
• Characterization of a new enzyme oxidizing omega-amino group of aminocarboxyric acid, aminoalcohols and amines from Phialemonium sp AIU 274

  Kimiyasu Isobe; Tomoko Sasaki; Yuusuke Aigami; Miwa Yamada; Shigenobu Kishino; Jun Ogawa

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Dec. 2013, Peer-reviewed

  
• Characterization of a trifunctional fatty acid desaturase from oleaginous filamentous fungus Mortierella alpina 1S-4 using a yeast expression system

  Hiroshi Kikukawa; Eiji Sakuradani; Shigenobu Kishino; Si-Bum Park; Akinori Ando; Jun Shima; Misa Ochiai; Sakayu Shimizu; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Dec. 2013, Peer-reviewed

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• Isolation and Characterization of a Docosahexaenoic Acid-Phospholipids Producing Microorganism Crypthecodinium sp D31

  Tomoyo Okuda; Akinori Ando; Eiji Sakuradani; Jun Ogawa

  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, Dec. 2013, Peer-reviewed

  
• The rhizosphere microbial community in a multiple parallel mineralization system suppresses the pathogenic fungus Fusarium oxysporum

  Kazuki Fujiwara; Yuichiro Iida; Takashi Iwai; Chihiro Aoyama; Ryuya Inukai; Akinori Ando; Jun Ogawa; Jun Ohnishi; Fumihiro Terami; Masao Takano; Makoto Shinohara

  MICROBIOLOGYOPEN, Dec. 2013, Peer-reviewed

  
• Microbial production of functional polyunsaturated fatty acids and their derivatives

  Jun Ogawa; Eiji Sakuradani; Shigenobu Kishino; Akinori Ando; Kenzo Yokozeki; Sakayu Shimizu

  Microbial Production: From Genome Design to Cell Engineering, 01 Nov. 2013, Peer-reviewed

  
• Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

  Shigenobu Kishino; Michiki Takeuchi; Si-Bum Park; Akiko Hirata; Nahoko Kitamura; Jun Kunisawa; Hiroshi Kiyono; Ryo Iwamoto; Yosuke Isobe; Makoto Arita; Hiroyuki Arai; Kazumitsu Ueda; Jun Shima; Satomi Takahashi; Kenzo Yokozeki; Sakayu Shimizu; Jun Ogawa

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Oct. 2013, Peer-reviewed

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• Subterminal oxidation of n-alkanes in achlorophyllous alga Prototheca sp.

  Eiji Sakuradani; Yusuke Natsume; Yasushi Takimura; Jun Ogawa; Sakayu Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Oct. 2013, Peer-reviewed

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• Metabolic engineering for the production of polyunsaturated fatty acids by oleaginous fungus Mortierella alpina 1S-4

  Eiji Sakuradani; Akinori Ando; Sakayu Shimizu; Jun Ogawa

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Oct. 2013, Peer-reviewed

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• Enzymatic synthesis of chiral amino acid sulfoxides by Fe(II)/alpha-ketoglutarate-dependent dioxygenase

  Makoto Hibi; Takashi Kawashima; Hiroko Yajima; Sergey V. Smirnov; Tomohiro Kodera; Masakazu Sugiyama; Sakayu Shimizu; Kenzo Yokozeki; Jun Ogawa

  TETRAHEDRON-ASYMMETRY, Sep. 2013, Peer-reviewed

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• Breeding of a Cyclic Imide-Assimilating Bacterium, Pseudomonas putida s52, for High Efficiency Production of Pyruvate

  Makoto Hibi; Nobuyuki Horinouchi; Weihao Tu; Chee-Leong Soong; Masashi Ito; Toshinori Segawa; Xiaoqing Mu; Tairo Hagishita; Kenzo Yokozeki; Sakayu Shimizu; Jun Ogawa

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Aug. 2013, Peer-reviewed

  
• 乳酸菌における不飽和脂肪酸飽和化代謝の解析と脂肪酸変換への応用

  岸野重信; 小川 順

  食品工業, Jul. 2013

  
• Characterization and application of a l-specific amino acid oxidase from Rhodococcus sp. AIU LAB-3

  Kimiyasu Isobe; Shiina Satou; Erika Matsumoto; Sachiko Yoshida; Miwa Yamada; Makoto Hibi; Jun Ogawa

  Journal of Bioscience and Bioengineering, Jun. 2013, Peer-reviewed

  
• A novel L-isoleucine-4 '-dioxygenase and L-isoleucine dihydroxylation cascade in Pantoea ananatis

  Sergey V. Smirnov; Pavel M. Sokolov; Veronika A. Kotlyarova; Natalya N. Samsonova; Tomohiro Kodera; Masakazu Sugiyama; Takayoshi Torii; Makoto Hibi; Sakayu Shimizu; Kenzo Yokozeki; Jun Ogawa

  MICROBIOLOGYOPEN, Jun. 2013, Peer-reviewed

  
• Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD

  Hui-Min Qin; Takuya Miyakawa; Min Ze Jia; Akira Nakamura; Jun Ohtsuka; You-Lin Xue; Takashi Kawashima; Takuya Kasahara; Makoto Hibi; Jun Ogawa; Masaru Tanokura

  PLOS ONE, May 2013, Peer-reviewed

  
• Hydroxy fatty acid production by Pediococcus sp.

  Michiki Takeuchi; Shigenobu Kishino; Kaori Tanabe; Akiko Hirata; Si-Bum Park; Sakayu Shimizu; Jun Ogawa

  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Apr. 2013, Peer-reviewed

  
• Hydroxy fatty acid production by Pediococcus sp.

  Michiki Takeuchi; Shigenobu Kishino; Kaori Tanabe; Akiko Hirata; Si-Bum Park; Sakayu Shimizu; Jun Ogawa

  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Apr. 2013, Peer-reviewed

  
• L-Leucine 5-hydroxylase of Nostoc punctiforme is a novel type of Fe(II)/alpha-ketoglutarate-dependent dioxygenase that is useful as a biocatalyst

  Makoto Hibi; Takashi Kawashima; Pavel M. Sokolov; Sergey V. Smirnov; Tomohiro Kodera; Masakazu Sugiyama; Sakayu Shimizu; Kenzo Yokozeki; Jun Ogawa

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Mar. 2013, Peer-reviewed

  
• オメガ３脂肪酸含有油脂の微生物による生産と変換

  櫻谷英治; 岸野重信; 安藤晃規; 新井洋由; 植田和光; 小川 順

  BIOINDUSTRY, Feb. 2013

  
• 乳酸菌の新たな脂肪酸代謝―機能性脂肪酸生産と腸内脂質代謝制御への展開−

  岸野重信; 小川 順

  化学と生物, 51 (11), 738-744, 2013

  
• 油糧糸状菌Mortierella alpinaによるEPAの常温発酵生産

  安藤晃規; 櫻谷英治; 小川 順

  バイオサイエンスとインダストリー, 2013

  
• 「特集：美味しい健康生活は微生物が作る ～作物生産、食品素材開発、健康支援～」 特集によせて

  OGAWA Jun

  生物工学会誌, 2013, Peer-reviewed

  
• オメガ３脂肪酸-より良い脂質バランスを実現するための機能解析と製品・生産法開発-

  小川 順; 新井洋由; 植田和光

  BIOINDUSTRY, 2013

  
• 腸内細菌に特異な脂質代謝「脂肪酸飽和化反応」に関与する新規酵素系の機能解析と応用

  OGAWA Jun

  日本応用酵素協会誌, 2013

  
• An organic acid-tolerant HAA1-overexpression mutant of an industrial bioethanol strain of Saccharomyces cerevisiae and its application to the production of bioethanol from sugarcane molasses

  Takuya Inaba; Daisuke Watanabe; Yoko Yoshiyama; Koichi Tanaka; Jun Ogawa; Hiroshi Takagi; Hitoshi Shimoi; Jun Shima

  AMB EXPRESS, 2013, Peer-reviewed

  
• 美味しい健康生活は微生物が作る ～作物生産、食品素材開発、健康支援～

  OGAWA Jun

  バイオサイエンスとインダストリー, 2013, Peer-reviewed

  
• Novel Fatty Acid Metabolism of Lactic Acid Bacteria:Application to Functional Fatty Acid Production and Gut Lipid Metabolism Control

  KISHINO Shigenobu; OGAWA Jun

  KAGAKU TO SEIBUTSU, 2013

  
• 乳酸菌における不飽和脂肪酸の飽和化反応に 関わる新規酵素群の機能解析

  岸野重信; 小川 順

  バイオサイエンスとインダストリー, 2013

  
• A novel Fe(II)/alpha-ketoglutarate-dependent dioxygenase from Burkholderia ambifaria has beta-hydroxylating activity of N-succinyl L-leucine

  M. Hibi; T. Kawashima; T. Kasahara; P. M. Sokolov; S. V. Smirnov; T. Kodera; M. Sugiyama; S. Shimizu; K. Yokozeki; J. Ogawa

  LETTERS IN APPLIED MICROBIOLOGY, Dec. 2012, Peer-reviewed

  
• Identification of an acetate-tolerant strain of Saccharomyces cerevisiae and characterization by gene expression analysis

  Yutaka Haitani; Koichi Tanaka; Mami Yamamoto; Toshihide Nakamura; Akira Ando; Jun Ogawa; Jun Shima

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Dec. 2012, Peer-reviewed

  
• Enhancement of Acetic Acid Tolerance in Saccharomyces cerevisiae by Overexpression of the HAA1 Gene, Encoding a Transcriptional Activator

  Koichi Tanaka; Yukari Ishii; Jun Ogawa; Jun Shima

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Nov. 2012, Peer-reviewed

  
• Polyunsaturated fatty acids production and transformation by Mortierella alpina and anaerobic bacteria

  Jun Ogawa; Eiji Sakuradani; Shigenobu Kishino; Akinori Ando; Kenzo Yokozeki; Sakayu Shimizu

  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Oct. 2012, Peer-reviewed

  
• Polyunsaturated fatty acids production and transformation by Mortierella alpina and anaerobic bacteria

  Jun Ogawa; Eiji Sakuradani; Shigenobu Kishino; Akinori Ando; Kenzo Yokozeki; Sakayu Shimizu

  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Oct. 2012, Peer-reviewed

  
• Expression, purification, crystallization and preliminary X-ray analysis of a novel N-substituted branched-chain l-amino-acid dioxygenase from Burkholderia ambifaria AMMD

  Hui-Min Qin; Takuya Miyakawa; Akira Nakamura; You-Lin Xue; Takashi Kawashima; Takuya Kasahara; Makoto Hibi; Jun Ogawa; Masaru Tanokura

  ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, Sep. 2012, Peer-reviewed

  
• Expression, purification, crystallization and preliminary X-ray analysis of 4-hydroxy-3-methyl-2-keto-pentanoate aldolase (asHPAL) from Arthrobacter simplex strain AKU 626

  Linjun Guo; Masahiko Okai; Tomoko Mase; Fabiana Lica Imai; Takuya Miyakawa; Koji Nagata; Hiroyuki Yamanaka; Hidemi Fujii; Makoto Hibi; Jun Ogawa; Masaru Tanokura

  ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS, Aug. 2012, Peer-reviewed

  
• Β-Aryl-Β-amino acid aminotransferase from Variovorax sp. JH2 is useful for enantioselective Β-phenylalanine production

  Makoto Hibi; Junichi Mano; Tairo Hagishita; Jun Shima; Sakayu Shimizu; Jun Ogawa

  Biocatalysis and Agricultural Biotechnology, Jul. 2012, Peer-reviewed

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• Oxidative pyrimidine metabolism in Rhodococcus erythropolis useful for valuable nucleoside synthesis: Discovery of a novel amidohydorolase, ureidomalonase

  Nobuyuki Horinouchi; Chee-Leong Soon; Sakayu Shimizu; Jun Ogawa

  Biocatalysis and Agricultural Biotechnology, Jul. 2012, Peer-reviewed

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• Cloning and sequencing of a gene encoding of aldehyde oxidase in Pseudomonas sp AIU 362

  Yasutaka Sasaki; Nobuyuki Urano; Michihiko Kataoka; Jun Ogawa; Akira Iwasaki; Junzo Hasegawa; Kimiyasu Isobe; Sakayu Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Jul. 2012, Peer-reviewed

  
• Β-Aryl-Β-amino acid aminotransferase from Variovorax sp. JH2 is useful for enantioselective Β-phenylalanine production

  Makoto Hibi; Junichi Mano; Tairo Hagishita; Jun Shima; Sakayu Shimizu; Jun Ogawa

  Biocatalysis and Agricultural Biotechnology, Jul. 2012, Peer-reviewed

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• Oxidative pyrimidine metabolism in Rhodococcus erythropolis useful for valuable nucleoside synthesis: Discovery of a novel amidohydorolase, ureidomalonase

  Nobuyuki Horinouchi; Chee-Leong Soon; Sakayu Shimizu; Jun Ogawa

  Biocatalysis and Agricultural Biotechnology, Jul. 2012, Peer-reviewed

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• Extracellular oxidases of Cerrena sp. complementarily functioning in artificial dye decolorization including laccase, manganese peroxidase, and novel versatile peroxidases

  Makoto Hibi; Satoko Hatahira; Masato Nakatani; Kenzo Yokozeki; Sakayu Shimizu; Jun Ogawa

  Biocatalysis and Agricultural Biotechnology, Jul. 2012, Peer-reviewed

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• Simple and convenient measurement of enzyme reaction by high sensitive signal accumulation ISFET biosensor (AMIS Sensor) and Micro Bioactivity Analyzer

  Yasutaka Sasaki; Jun Ogawa; Toshio Tani

  Biocatalysis and Agricultural Biotechnology, Jul. 2012, Peer-reviewed

  
• Development of a whole-cell biocatalyst co-expressing P450 monooxygenase and glucose dehydrogenase for synthesis of epoxyhexane

  Akasit Siriphongphaew; Pimpaya Pisnupong; Jirarut Wongkongkatep; Pranee Inprakhon; Alisa S. Vangnai; Kohsuke Honda; Hisao Ohtake; Junichi Kato; Jun Ogawa; Sakayu Shimizu; Vlada B. Urlacher; Rolf D. Schmid; Thunyarat Pongtharangkul

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Jul. 2012, Peer-reviewed

  
• Development of Biocatalytic Processes in Japan and Germany: From Research Synergies to Industrial Applications

  Harald Groeger; Yasuhisa Asano; Uwe T. Bornscheuer; Jun Ogawa

  CHEMISTRY-AN ASIAN JOURNAL, Jun. 2012, Peer-reviewed

  
• Construction of microbial platform for an energy-requiring bioprocess: practical 2 '-deoxyribonucleoside production involving a C-C coupling reaction with high energy substrates

  Nobuyuki Horinouchi; Takafumi Sakai; Takako Kawano; Seiichiro Matsumoto; Mie Sasaki; Makoto Hibi; Jun Shima; Sakayu Shimizu; Jun Ogawa

  MICROBIAL CELL FACTORIES, Jun. 2012, Peer-reviewed

  
• A novel family of bacterial dioxygenases that catalyse the hydroxylation of free l-amino acids

  Sergey V. Smirnov; Pavel M. Sokolov; Tomohiro Kodera; Masakazu Sugiyama; Makoto Hibi; Sakayu Shimizu; Kenzo Yokozeki; Jun Ogawa

  FEMS MICROBIOLOGY LETTERS, Jun. 2012, Peer-reviewed

  
• Effect of pretreatment of hydrothermally processed rice straw with laccase-displaying yeast on ethanol fermentation

  Akihito Nakanishi; Jun Gu Bae; Kotaro Fukai; Naoki Tokumoto; Kouichi Kuroda; Jun Ogawa; Masato Nakatani; Sakayu Shimizu; Mitsuyoshi Ueda

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, May 2012, Peer-reviewed

  
• Hydrolysis and Formation of Hydantoins

  Jun Ogawa; Nobuyuki Horinouchi; Sakayu Shimizu

  Enzyme Catalysis in Organic Synthesis, Third Edition, 20 Apr. 2012, Peer-reviewed

  
• バイオプラ最前線 -バイオマスからのモノマー生産を支援するバイオリピッドプラットフォームの構築-

  小川 順; 櫻谷英治; 岸野重信; 日比 慎; 安藤晃規

  バイオプラジャーナル, Feb. 2012

  
• 腸内細菌に特異な脂質代謝「脂肪酸飽和化反応」に関与する新規酵素系の機能解析と応用

  小川 順; 岸野重信; 横関健三; 清水 昌

  日本応用酵素協会誌, Feb. 2012

  
• 高度不飽和脂肪酸・共役脂肪酸含有油脂の微生物生産

  小川 順; 櫻谷英治; 岸野重信; 安藤晃規; 清水 昌

  バイオテクノロジーシリーズ「微生物を活用した新世代の有用物質生産技術」第?編 第7章 穴澤秀治 監修シーエムシー出版, 東京, 2012

  
• 「油脂発酵クロニクル」. 生物工学基礎講座 バイオよもやま話

  小川 順

  生物工学会誌, 2012

  
• アラキドン酸および関連高度不飽和脂肪酸を含む微生物油脂生産

  櫻谷英治; 安藤晃規; 清水 昌; 小川 順

  オレオサイエンス, 2012

  
• Isolation of a novel strain of Candida shehatae for ethanol production at elevated temperature

  Ayumi Tanimura; Toshihide Nakamura; Itsuki Watanabe; Jun Ogawa; Jun Shima

  SPRINGERPLUS, 2012, Peer-reviewed

  
• Isolation of a novel strain of Candida shehatae for ethanol production at elevated temperature

  Ayumi Tanimura; Toshihide Nakamura; Itsuki Watanabe; Jun Ogawa; Jun Shima

  SPRINGERPLUS, 2012, Peer-reviewed

  
• Microbial oxidases catalyzing conversion of glycolaldehyde into glyoxal

  Kimiyasu Isobe; Michihiko Kataoka; Jun Ogawa; Junzo Hasegawa; Sakayu Shimizu

  NEW BIOTECHNOLOGY, Jan. 2012, Peer-reviewed

  
• Novel multi-component enzyme machinery in lactic acid bacteria catalyzing C=C double bond migration useful for conjugated fatty acid synthesis

  Shigenobu Kishino; Si-Bum Park; Michiki Takeuchi; Kenzo Yokozeki; Sakayu Shimizu; Jun Ogawa

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Dec. 2011, Peer-reviewed

  
• Novel multi-component enzyme machinery in lactic acid bacteria catalyzing C=C double bond migration useful for conjugated fatty acid synthesis

  Shigenobu Kishino; Si-Bum Park; Michiki Takeuchi; Kenzo Yokozeki; Sakayu Shimizu; Jun Ogawa

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Dec. 2011, Peer-reviewed

  
• Characterization of Bacillus thuringiensis L-Isoleucine Dioxygenase for Production of Useful Amino Acids

  Makoto Hibi; Takashi Kawashima; Tomohiro Kodera; Sergey V. Smirnov; Pavel M. Sokolov; Masakazu Sugiyama; Sakayu Shimizu; Kenzo Yokozeki; Jun Ogawa

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Oct. 2011, Peer-reviewed

  
• Characterization of Bacillus thuringiensis L-Isoleucine Dioxygenase for Production of Useful Amino Acids

  Makoto Hibi; Takashi Kawashima; Tomohiro Kodera; Sergey V. Smirnov; Pavel M. Sokolov; Masakazu Sugiyama; Sakayu Shimizu; Kenzo Yokozeki; Jun Ogawa

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Oct. 2011, Peer-reviewed

  
• 代謝的視点からの機能探索に基づく産業プロセス用酵素開発

  小川 順; 櫻谷英治; 岸野重信; 日比 慎; 堀之内伸行; 横関健三; 清水 昌

  BIOINDUSTRY, Aug. 2011

  
• Bioconversion of substituted naphthalenes and β-eudesmol with the cytochrome P450 BM3 variant F87V

  Norihiko Misawa; Miho Nodate; Toshihiko Otomatsu; Keiko Shimizu; Chie Kaido; Miho Kikuta; Akira Ideno; Hiroshi Ikenaga; Jun Ogawa; Sakayu Shimizu; Kazutoshi Shindo

  Applied Microbiology and Biotechnology, Apr. 2011, Peer-reviewed

  
• Bioconversion of substituted naphthalenes and beta-eudesmol with the cytochrome P450 BM3 variant F87V

  Norihiko Misawa; Miho Nodate; Toshihiko Otomatsu; Keiko Shimizu; Chie Kaido; Miho Kikuta; Akira Ideno; Hiroshi Ikenaga; Jun Ogawa; Sakayu Shimizu; Kazutoshi Shindo

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Apr. 2011, Peer-reviewed

  
• A novel L-isoleucine metabolism in Bacillus thuringiensis generating (2S,3R,4S)-4-hydroxyisoleucine, a potential insulinotropic and anti-obesity amino acid

  Jun Ogawa; Tomohiro Kodera; Sergey V. Smirnov; Makoto Hibi; Natalia N. Samsonova; Ryoukichi Koyama; Hiroyuki Yamanaka; Junichi Mano; Takashi Kawashima; Kenzo Yokozeki; Sakayu Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Mar. 2011, Peer-reviewed

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• Linoleic Acid Isomerase in Lactobacillus plantarum AKU1009a Proved to Be a Multi-Component Enzyme System Requiring Oxidoreduction Cofactors

  Shigenobu Kishino; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Feb. 2011, Peer-reviewed

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• Linoleic Acid Isomerase in Lactobacillus plantarum AKU1009a Proved to Be a Multi-Component Enzyme System Requiring Oxidoreduction Cofactors

  Shigenobu Kishino; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Feb. 2011, Peer-reviewed

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• Improvement of aldehyde tolerance and sequential aldol condensation activity of deoxyriboaldolase via immobilization on interparticle pore type mesoporous silica

  Takayuki Y. Nara; Hideaki Togashi; Seigo Ono; Miki Egami; Chisato Sekikawa; Yo-hei Suzuki; Isao Masuda; Jun Ogawa; Nobuyuki Horinouchi; Sakayu Shimizu; Fujio Mizukami; Tatsuo Tsunoda

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Feb. 2011, Peer-reviewed

  
• アミノ酸水酸化触媒としてのα-ケトグルタル酸依存性ジオキシゲナーゼ

  日比 慎; 小川 順

  バイオサイエンスとインダストリー, 2011

  
• バイオベースインダストリーを創出する 有用微生物機能の設計・探索・開発 「特集2020年のバイオインダストリー －終わりのはじまりがそこに！－」

  小川 順

  生物工学会誌, 2011

  
• 第6回 油脂生産性糸状菌Mortierella alpinaによる機能性脂質生産 連載「微生物の産業利用-はたらく有用微生物-」

  小川 順; 櫻谷英治; 安藤晃規; 清水 昌

  Microbiol. Cult. Coll., 2011

  
• 腸内細菌に特異な脂質代謝 『脂肪酸飽和化反応』 に関与する新規酵素系の機能解析と応用

  小川 順; 岸野重信; 横関健三; 清水 昌

  日本応用酵素協会誌, 2011

  
• Metabolic engineering of Escherichia coli to produce (2S, 3R, 4S)-4-hydroxyisoleucine

  Sergey V. Smirnov; Tomohiro Kodera; Natalya N. Samsonova; Veronika A. Kotlyarova; Natalya Yu Rushkevich; Alexander D. Kivero; Pavel M. Sokolov; Makoto Hibi; Jun Ogawa; Sakayu Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Oct. 2010, Peer-reviewed

  
• Two laccase isoenzymes and a peroxidase of a commercial laccase-producing basidiomycete, Trametes sp Ha1

  Masato Nakatani; Makoto Hibi; Masashi Minoda; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu

  NEW BIOTECHNOLOGY, Sep. 2010, Peer-reviewed

  
• Cloning, sequencing and expression analysis of a gene encoding alcohol oxidase in Paenibacillus sp AIU 311

  Yasutaka Sasaki; Michihiko Kataoka; Nobuyuki Urano; Jun Ogawa; Akira Iwasaki; Junzo Hasegawa; Kimiyasu Isobe; Sakayu Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Aug. 2010, Peer-reviewed

  
• Engineering of Bacterial Cytochrome P450 Monooxygenase as Biocatalysts for Chemical Synthesis and Environmental Bioremediation

  Jun Ogawa; Qing-Shan Li; Sakayu Shimizu; Vlada Urlacher; Rolf D. Schmid

  Biocatalysis and Biomolecular Engineering, 19 Jul. 2010, Peer-reviewed

  
• Engineering of Bacterial Cytochrome P450 Monooxygenase as Biocatalysts for Chemical Synthesis and Environmental Bioremediation

  Jun Ogawa; Qing-Shan Li; Sakayu Shimizu; Vlada Urlacher; Rolf D. Schmid

  Biocatalysis and Biomolecular Engineering, 19 Jul. 2010, Peer-reviewed

  
• Microbial production of conjugated gamma-linolenic acid from gamma-linolenic acid by Lactobacillus plantarum AKU 1009a

  S. Kishino; J. Ogawa; A. Ando; K. Yokozeki; S. Shimizu

  JOURNAL OF APPLIED MICROBIOLOGY, Jun. 2010, Peer-reviewed

  
• Microbial production of conjugated gamma-linolenic acid from gamma-linolenic acid by Lactobacillus plantarum AKU 1009a

  S. Kishino; J. Ogawa; A. Ando; K. Yokozeki; S. Shimizu

  JOURNAL OF APPLIED MICROBIOLOGY, Jun. 2010, Peer-reviewed

  
• Arachidonic Acid-Producing Mortierella alpina: Creation of Mutants, Isolation of the Related Enzyme Genes, and Molecular Breeding

  Eiji Sakuradani; Akinori Ando; Jun Ogawa; Sakayu Shimizu

  Single Cell Oils: Microbial and Algal Oils: Second Edition, 01 May 2010, Peer-reviewed

  
• Oils, Microbial Production.

  Sakuradani, E; J. Ogawa; S. Kishino; A. Ando; K. Yokozeki; S. Shimizu

  Encyclopedia of Industrial Biotechnolog Bioprocess, Bioseparation, and Cell Technology (ed. by M.C. Flickinger) John Wiley & Sons, in press, 2010, Peer-reviewed

  
• 有用脂肪酸の生産

  小川 順; 櫻谷英治; 岸野重信; 安藤晃規; 清水 昌

  酵素利用技術体系 第5編 −第1章− 第5節2，小宮山眞 監修, エヌ・ティー・エス, 東京, 2010

  
• 特集 バイオマスからの有用物質生産プロセス最前線 脂肪酸誘導体の合成

  岸野重信; 小川 順

  BIO INDUSTRY, 2010

  
• バイオマスからの有用物質生産プロセス最前線 脂肪酸誘導体の合成

  岸野重信; 小川 順

  BIO INDUSTRY, 27 (11), 32-37, 2010

  
• A novel L-isoleucine hydroxylating enzyme, L-isoleucine dioxygenase from Bacillus thuringiensis, produces (2S,3R,4S)-4-hydroxyisoleucine

  Tomohiro Kodera; Sergey V. Smirnov; Natalya N. Samsonova; Yury I. Kozlov; Ryokichi Koyama; Makoto Hibi; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Dec. 2009, Peer-reviewed

  
• Screening and characterization of a phosphopentomutase useful for enzymatic production of 2 '-deoxyribonucleoside

  Nobuyuki Horinouchi; Takako Kawano; Takafumi Sakai; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Jun Ogawa; Sakayu Shimizu

  NEW BIOTECHNOLOGY, Oct. 2009, Peer-reviewed

  
• Enantioselective ester hydrolase from Sphingobacterium sp 238C5 useful for chiral resolution of beta-phenylalanine and for its beta-peptide synthesis

  Jun Ogawa; Junichi Mano; Tairo Hagishita; Sakayu Shimizu

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Oct. 2009, Peer-reviewed

  
• Establishment of Agrobacterium tumefaciens-Mediated Transformation of an Oleaginous Fungus, Mortierella alpina 1S-4, and Its Application for Eicosapentaenoic Acid Producer Breeding

  Akinori Ando; Yosuke Sumida; Hiroaki Negoro; Dian Anggraini Suroto; Jun Ogawa; Eiji Sakuradani; Sakayu Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Sep. 2009, Peer-reviewed

  
• Microbial production of conjugated fatty acids

  Shigenobu Kishino; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu

  Lipid Technology, Aug. 2009, Peer-reviewed

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• Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production

  Shigenobu Kishino; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Aug. 2009, Peer-reviewed

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• Improved production of various polyunsaturated fatty acids through filamentous fungus Mortierella alpina breeding

  Eiji Sakuradani; Akinori Ando; Jun Ogawa; Sakayu Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Aug. 2009, Peer-reviewed

  
• Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production

  Shigenobu Kishino; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Aug. 2009, Peer-reviewed

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• Microbial production of conjugated fatty acids

  Shigenobu Kishino; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu

  Lipid Technology, Aug. 2009, Peer-reviewed

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• Transformation of an oleaginous zygomycete Mortierella alpina 1S-4 with the carboxin resistance gene conferred by mutation of the iron-sulfur subunit of succinate dehydrogenase

  Akinori Ando; Eiji Sakuradani; Kota Horinaka; Jun Ogawa; Sakayu Shimizu

  CURRENT GENETICS, Jun. 2009, Peer-reviewed

  
• 微生物酵素の産業利用-その最前線を探る-

  小川 順; 清水 昌

  化学と生物, 01 Jun. 2009

  
• Selective production of cis-9,trans-11 isomer of conjugated linoleic acid from trans-vaccenic acid methyl ester by Delacroixia coronata

  A. Ando; J. Ogawa; S. Sugimoto; S. Kishino; E. Sakuradani; K. Yokozeki; S. Shimizu

  JOURNAL OF APPLIED MICROBIOLOGY, May 2009, Peer-reviewed

  
• Selective production of cis-9,trans-11 isomer of conjugated linoleic acid from trans-vaccenic acid methyl ester by Delacroixia coronata

  A. Ando; J. Ogawa; S. Sugimoto; S. Kishino; E. Sakuradani; K. Yokozeki; S. Shimizu

  JOURNAL OF APPLIED MICROBIOLOGY, May 2009, Peer-reviewed

  
• Development of biocatalytic processes in japan and germany: From research synergies to industrial applications

  H. Gröger; Y. Asano; U.T. Bornscheuer; J. Ogawa

  Chemistry - An Asian Journal, May 2009, Peer-reviewed

  
• Fatty Acid Desaturation and Elongation Reactions of Trichoderma sp 1-OH-2-3

  Akinori Ando; Jun Ogawa; Shigenobu Kishino; Taiyo Ito; Norifumi Shirasaka; Eiji Sakuradani; Kenzo Yokozeki; Sakayu Shimizu

  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, Mar. 2009, Peer-reviewed

  
• Fatty Acid Desaturation and Elongation Reactions of Trichoderma sp 1-OH-2-3

  Akinori Ando; Jun Ogawa; Shigenobu Kishino; Taiyo Ito; Norifumi Shirasaka; Eiji Sakuradani; Kenzo Yokozeki; Sakayu Shimizu

  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, Mar. 2009, Peer-reviewed

  
• The 11th Swiss-Japanese Joint Meeting on Biotechnology and Bioprocess Development

  片山高嶺; 小川 順

  バイオサイエンスとインダストリー = Bioscience & industry, 01 Feb. 2009, Peer-reviewed

  
• Production and characterization of alcohol oxidase from Penicillium purpurescens AIU 063

  Kimiyasu Isobe; Toyofumi Takahashi; Jun Ogawa; Michihiko Kataoka; Sakayu Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Feb. 2009, Peer-reviewed

  
• the 11th Swiss-Japanese Joint Meeting on Biotechnology and Bioprocess Debelopment

  片山高嶺; 小川 順

  バイオサイエンスとインダストリー, 2009, Peer-reviewed

  
• Sakuradani, E., A. Ando, J. Ogawa, S. Shimizu

  Improved production of; various polyunsaturated fatty acids; through filamentous fungus Mortierella alpina breeding

  Appl. Microbiol. Biotechnol., 2009, Peer-reviewed

  
• Production of functional lipids by microorganisms: arachidonic acid and related polyunsaturated fatty acids

  E. Sakuradani; A. Ando; J. Ogawa; S. Shimizu

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2009, Peer-reviewed

  
• Microbial Production of DNA Building Blocks

  Jun Ogawa; Nobuyuki Horinouchi; Sakayu Shimizu

  Multi-Step Enzyme Catalysis: Biotransformations and Chemoenzymatic Synthesis, 17 Oct. 2008, Peer-reviewed

  
• Purification and Characterization of a New Aldehyde Oxidase from Pseudomonas sp AIU 362

  Yasutaka Sasaki; Kimiyasu Isobe; Michihiko Kataoka; Jun Ogawa; Akira Iwasaki; Junzo Hasegawa; Sakayu Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Sep. 2008, Peer-reviewed

  
• Rerouting of pyruvate metabolism during acid adaptation in Lactobacillus bulgaricus

  Annabelle Fernandez; Jun Ogawa; Stephanie Penaud; Samira Boudebbouze; Dusko Ehrlich; Maarten van de Guchte; Emmanuelle Maguin

  PROTEOMICS, Aug. 2008, Peer-reviewed

  
• Superoxide dismutases exhibit oxidase activity on aldehyde alcohols similar to alcohol oxidase from Paenibacillus sp AIU 311

  Kimiyasu Isobe; Ayako Kato; Yasutaka Sasaki; Michihiko Kataoka; Jun Ogawa; Akira Iwasaki; Junzo Hasegawa; Sakayu Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Jun. 2008, Peer-reviewed

  
• フランス国立農業研究所での乳酸菌研究体験談

  小川 順

  日本乳酸菌学会誌 = Journal of Japan Society for Lactic Acid Bacteria, 15 Mar. 2008, Peer-reviewed

  
• Secretion of flavins by Shewanella species and their role in extracellular electron transfer

  Harald von Canstein; Jun Ogawa; Sakayu Shimizu; Jonathan R. Lloyd

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Feb. 2008, Peer-reviewed

  
• Secretion of flavins by Shewanella species and their role in extracellular electron transfer

  Harald von Canstein; Jun Ogawa; Sakayu Shimizu; Jonathan R. Lloyd

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Feb. 2008, Peer-reviewed

  
• 乳酸菌による共役脂肪酸生産

  岸野重信; 小川 順; 横関健三; 清水 昌

  バイオサイエンスとインダストリー, 01 Feb. 2008

  
• -留学報告-フランス国立農業研究所での乳酸菌研究体験談

  小川 順

  日本乳酸菌学会誌, 2008, Peer-reviewed

  
• 特集 機能性脂質生産の新たなターゲットを探る-特集によせて

  小川 順; 秋 庸裕; 永尾寿浩

  生物工学誌, 2008, Peer-reviewed

  
• 新春特集 微生物機能による反応と物質生産 序論 ユニークな微生物機能の探索・開発と物質生産への利用

  小川 順; 岸野重信; 清水 昌

  月刊 ファインケミカル, 2008, Peer-reviewed

  
• お口の恋人"酵素". 未来をつくるバイオ -酒づくりから再生医療まで60話-,

  小川 順

  日本乳酸菌学会誌, 19 (1), 46-50, 2008

  
• 酵素法による共役脂肪酸類の合成

  小川 順; 岸野重信; 清水 昌

  月刊ファインケミカル, Dec. 2007

  
• Purification and characterization of a novel alcohol oxidase from Paenibacillus sp AIU 311

  Kimiyasu Isobe; Ayako Kato; Yasutaka Sasaki; Shuuya Suzuki; Michihiko Kataoka; Jun Ogawa; Akira Iwasaki; Junzo Hasegawa; Sakayu Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Aug. 2007, Peer-reviewed

  
• A novel strategy for enzymatic synthesis of 4-hydroxyisoleucine: identification of an enzyme possessing HMKP (4-hydroxy-3-methyl-2-keto-pentanoate) aldolase activity

  Sergey V. Smirnov; Natalya N. Samsonova; Anna E. Novikova; Nikolay G. Matrosov; Natalya Y. Rushkevich; Tomohiro Kodera; Jun Ogawa; Hiroyuki Yamanaka; Sakayu Shimizu

  FEMS MICROBIOLOGY LETTERS, Aug. 2007, Peer-reviewed

  
• Synthesis of 4-hydroxyisoleucine by the aldolase-transaminase coupling reaction and basic characterization of the aldolase from Arthrobacter simplex AKU 626

  Jun Ogawa; Hiroyuki Yamanaka; Junichi Mano; Yuko Doi; Nobuyuki Horinouchi; Tomohiro Kodera; Noriki Nio; Sergey V. Smirnov; Natalya N. Samsonova; Yury I. Kozlov; Sakayu Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Jul. 2007, Peer-reviewed

  
• Characterization of alcohol oxidase from Aspergillus ochraceus AIU 031

  Kimiyasu Isobe; Ayako Kato; Jun Ogawa; Michihiko Kataoka; Akira Iwasaki; Junzo Hasegawa; Sakayu Shimizu

  JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY, Jun. 2007, Peer-reviewed

  
• Screening and biochemical analysis of biocatalysts useful for chiral beta-amino acid synthesis - Abstracts

  Junichi Mano; Jun Ogawa; Sakayu Shimizu

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Nov. 2006, Peer-reviewed

  
• Microbial production of optically active beta-phenylalanine through stereoselective degradation of racemic beta-phenylalanine

  Junichi Mano; Jun Ogawa; Sakayu Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Aug. 2006, Peer-reviewed

  
• Biochemical retrosynthesis of 2 '-deoxyribonucleosides from glucose, acetaldehyde, and a nucleobase

  Nobuyuki Horinouchi; Jun Ogawa; Takako Kawano; Takafumi Sakai; Kyota Saito; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Sakayu Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Aug. 2006, Peer-reviewed

  
• Efficient production of 2-deoxyribose 5-phosphate from glucose and acetaldehyde by coupling of the alcoholic fermentation system of baker's yeast and deoxyriboaldolase-expressing Escherichia coli

  Nobuyuki Horinouchi; Jun Ogawa; Takako Kawano; Takafumi Sakai; Kyota Saito; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Sakayu Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Jun. 2006, Peer-reviewed

  
• One-pot microbial synthesis of 2 '-deoxyribonucleoside from glucose, acetaldehyde, and a nucleobase

  Nobuyuki Horinouchi; Jun Ogawa; Takako Kawano; Takafumi Sakai; Kyota Saito; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Sakayu Shimizu

  BIOTECHNOLOGY LETTERS, Jun. 2006, Peer-reviewed

  
• Microbial production of optically active beta-phenylalanine ethyl ester through stereoselective hydrolysis of racemic beta-phenylalanine ethyl ester

  J Ogawa; J Mano; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, May 2006, Peer-reviewed

  
• Screening and industrial application of unique microbial reactions involved in nucleic acid and lipid metabolisms

  J Ogawa; CL Soong; S Kishino; QS Li; N Horinouchi; S Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Mar. 2006, Peer-reviewed

  
• Screening and industrial application of unique microbial reactions involved in nucleic acid and lipid metabolisms

  J Ogawa; CL Soong; S Kishino; QS Li; N Horinouchi; S Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Mar. 2006, Peer-reviewed

  
• 共役脂肪酸の合成と変換に関与する微生物反応

  岸野重信; 安藤晃規; 小川 順; 清水 昌

  日本応用酵素協会誌, Feb. 2006

  
• 2'-デオキシリボヌクレオシドおよびDNAの工業生産 -微生物のヌクレオシド分解代謝の逆反応を利用した効率的なプロセスに期待-

  小川 順; 堀之内伸行; 清水 昌

  化学と生物, 2006

  
• Production of conjugated fatty acids by lactic acid bacteria

  J Ogawa; S Kishino; A Ando; S Sugimoto; K Mihara; S Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Oct. 2005, Peer-reviewed

  
• Production of conjugated fatty acids by lactic acid bacteria

  J Ogawa; S Kishino; A Ando; S Sugimoto; K Mihara; S Shimizu

  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Oct. 2005, Peer-reviewed

  
• Hydroxylation activity of P450BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds

  WT Sulistyaningdyah; J Ogawa; QS Li; C Maeda; Y Yano; RD Schmid; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Jun. 2005, Peer-reviewed

  
• Indole hydroxylation by bacterial cytochrome p450 BM-3 and modulation of activity by cumene hydroperoxide

  QS Li; J Ogawa; RD Schmid; S Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Feb. 2005, Peer-reviewed

  
• 特集 バイオテクニクス（Biotech-nics and -mix） 研究部会の最前線研究 機能性脂質の微生物生産

  小川 順; 櫻谷英治; 清水 昌

  生物工学会誌, 2005

  
• 乳酸菌による共役脂肪酸生産

  岸野 重信; 小川 順; 清水 昌

  応用微生物学研究, 2005

  
• Enzymes from Brewing Microorganisms as Functional Foods and Dietary Supplements

  OGAWA Jun; SHIMIZU Sakayu

  JOURNAL OF THE SOCIETY OF BREWING,JAPAN, 15 Dec. 2004

  
• Metabolism of polychlorinated dibenzo-p-dioxins by cytochrome P450BM-3 and its mutant

  WT Sulistyaningdyah; J Ogawa; QS Li; R Shinkyo; T Sakaki; K Inouye; RD Schmid; S Shimizu

  BIOTECHNOLOGY LETTERS, Dec. 2004, Peer-reviewed

  
• Improvement of arachidonic acid production by mutants with lower n-3 desaturation activity derived from Mortierella alpina 1S-4

  E Sakuradani; Y Hirano; N Kamada; M Nojiri; J Ogawa; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Dec. 2004, Peer-reviewed

  
• Conjugated linoleic acid production from castor oil by Lactobacillus plantarum JCM 1551

  Akinori Ando; Jun Ogawa; Shigenobu Kishino; Sakayu Shimizu

  Enzyme and Microbial Technology, 06 Jul. 2004, Peer-reviewed

  
• Conjugated linoleic acid production from castor oil by Lactobacillus plantarum JCM 1551

  A Ando; J Ogawa; S Kishino; S Shimizu

  ENZYME AND MICROBIAL TECHNOLOGY, Jul. 2004, Peer-reviewed

  
• 微生物による共役脂肪酸生産

  小川 順; 岸野重信; 安藤晃規; 杉本 聡; 清水 昌

  生物工学会誌, Jul. 2004

  
• Two extracellular proteins with alkaline peroxidase activity, a novel cytochrome c and a catalase-peroxidase, from Bacillus sp No. 13

  J Ogawa; WT Sulistyaningdyah; QS Li; H Tanaka; SX Xie; K Kano; T Ikeda; S Shimizu

  BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, Jun. 2004, Peer-reviewed

  
• Screening and development of novel microbial reactions involved in nucleic acid and lipid metabolisms

  J Ogawa

  NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY, 2004, Peer-reviewed

  
• Characterization of alkaliphilic laccase activity in the culture supernatant of Myrothecium verrucaria 24G-4 in comparison with bilirubin oxidase

  WT Sulistyaningdyah; J Ogawa; H Tanaka; C Maeda; S Shimizu

  FEMS MICROBIOLOGY LETTERS, Jan. 2004, Peer-reviewed

  
• Regiospecific analysis by ethanolysis of oil with immobilized Candida antarctica lipase

  Y Shimada; J Ogawa; Y Watanabe; T Nagao; A Kawashima; T Kobayashi; S Shimizu

  LIPIDS, Dec. 2003, Peer-reviewed

  
• Conjugated alpha-linolenic acid production from alpha-linolenic acid by Lactobacillus plantarum AKU 1009a

  S Kishino; J Ogawa; A Ando; S Shimizu

  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Oct. 2003, Peer-reviewed

  
• Conjugated alpha-linolenic acid production from alpha-linolenic acid by Lactobacillus plantarum AKU 1009a

  S Kishino; J Ogawa; A Ando; S Shimizu

  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Oct. 2003, Peer-reviewed

  
• CLA production from ricinoleic acid by lactic acid bacteria

  A Ando; J Ogawa; S Kishino; S Shimizu

  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, Sep. 2003, Peer-reviewed

  
• Construction of deoxyriboaldolase-overexpressing Escherichia coli and its application to 2-deoxyribose 5-phosphate synthesis from glucose and acetaldehyde for 2 '-deoxyribonucleoside production

  N Horinouchi; J Ogawa; T Sakai; T Kawano; S Matsumoto; M Sasaki; Y Mikami; S Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Jul. 2003, Peer-reviewed

  
• Microbial production of 2-deoxyribose 5-phosphate from acetaldehyde and triosephosphate for the synthesis of 2 '-deoxyribonucleosides

  J Ogawa; K Saito; T Sakai; N Horinouchi; T Kawano; S Matsumoto; M Sasaki; Y Mikami; S Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Apr. 2003, Peer-reviewed

  
• Structural analysis of conjugated linoleic acid produced by Lactobacillus plantarum, and factors affecting isomer production

  S Kishino; J Ogawa; A Ando; T Iwashita; T Fujita; H Kawashima; S Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Jan. 2003, Peer-reviewed

  
• CLA Production from Ricinoleic Acid by Lactic Acid Bacteria

  Akinori Ando; Jun Ogawa; Shigenobu Kishino; Sakayu Shimizu

  JAOCS, Journal of the American Oil Chemists' Society, 2003, Peer-reviewed

  
• Bilirubin dehydrogenase, an enzyme in Aspergillus ochraceus IB-3 useful for diagnostic measurement of bilirubin

  J Ogawa; WT Sulistyaningdyah; H Tanaka; K Kano; T Ikeda; S Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Nov. 2002, Peer-reviewed

  
• Production of 5,8,11-eicosatrienoic acid by Delta 5 and Delta 6 desaturation activity-enhanced mutant derived from a Delta 12 desaturation activity-defective mutant of Mortierella alpina 1S-4

  E Sakuradani; N Kamada; Y Hirano; M Nishihara; H Kawashima; K Akimoto; K Higashiyama; J Ogawa; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Nov. 2002, Peer-reviewed

  
• Ricinoleic acid and castor oil as substrates for conjugated linoleic acid production by washed cells of Lactobacillus plantarum

  S Kishino; J Ogawa; A Ando; Y Omura; S Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Oct. 2002, Peer-reviewed

  
• Industrial microbial enzymes: their discovery by screening and use in large-scale production of useful chemicals in Japan

  J Ogawa; S Shimizu

  CURRENT OPINION IN BIOTECHNOLOGY, Aug. 2002, Peer-reviewed

  
• Barbiturase, a novel zinc-containing amidohydrolase involved in oxidative pyrimidine metabolism

  CL Soong; J Ogawa; E Sakuradani; S Shimizu

  JOURNAL OF BIOLOGICAL CHEMISTRY, Mar. 2002, Peer-reviewed

  
• Conjugated linoleic acid production from linoleic acid by lactic acid bacteria

  S Kishino; J Ogawa; Y Omura; K Matsumura; S Shimizu

  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, Feb. 2002, Peer-reviewed

  
• 微生物による機能性脂質の生産（共著）

  小川 順

  科学と工業,76/4, 163-170, 2002, Peer-reviewed

  
• 微生物による共役リノール酸 (CLA) 生産

  小川 順; 岸野重信; 清水 昌

  バイオインダストリーとサイエンス, 2002

  
• Engineering cytochrome P450BM-3 for oxidation of polycyclic aromatic hydrocarbons

  QS Li; J Ogawa; RD Schmid; S Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Dec. 2001, Peer-reviewed

  
• Residue size at position 87 of cytochrome P450BM-3 determines its stereoselectivity in propylbenzene and 3-chlorostyrene oxidation

  QS Li; J Ogawa; RD Schmid; S Shimizu

  FEBS LETTERS, Nov. 2001, Peer-reviewed

  
• Novel amidohydrolytic reactions in oxidative pyrimidine metabolism: Analysis of the barbiturase reaction and discovery of a novel enzyme, ureidomalonase

  CL Soong; J Ogawa; S Shimizu

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Aug. 2001, Peer-reviewed

  
• Metabolic engineering of oleaginous fungus, Mortierella alpina

  SHIMIZU Sakayu; OGAWA Jun; SAKURADANI Eiji

  Bioscience & industry, 01 Jul. 2001, Peer-reviewed

  
• Metabolic engineering of Escherichia coli to produce (2S, 3R, 4S)-4-hydroxyisoleucine

  S.V. Smirnov; T. Kodera; N.N. Samsonova; V.A. Kotlyarova; N.Y. Rushkevich; A.D. Kivero; P.M. Sokolov; M. Hibi; J. Ogawa; S. Shimizu

  Applied Microbiology and Biotechnology, 25 May 2001, Peer-reviewed

  
• Purification, characterization, and gene cloning of purine nucleosidase from Ochrobactrum anthropi

  J Ogawa; S Takeda; SX Xie; H Hatanaka; T Ashikari; T Amachi; S Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Apr. 2001, Peer-reviewed

  
• Conjugated linoleic acid accumulation via 10-hydroxy-12 octadecaenoic acid during microaerobic transformation of linoleic acid by Lactobacillus acidophilus

  J Ogawa; K Matsumura; S Kishino; Y Omura; S Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Mar. 2001, Peer-reviewed

  
• Separative preparation of the four stereoisomers of beta-methylphenylalanine with N-carbamoyl amino acid amidohydrolases

  J Ogawa; A Ryono; SX Xie; RM Vohra; R Indrati; M Akamatsu; H Miyagawa; T Ueno; S Shimizu

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Feb. 2001, Peer-reviewed

  
• Cyclic ureide and imide metabolism in microorganisms producing a D-hydantoinase useful for D-amino acid production

  CL Soong; J Ogawa; S Shimizu

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Feb. 2001, Peer-reviewed

  
• Critical role of the residue size at position 87 in H2O2-dependent substrate hydroxylation activity and H2O2 inactivation of cytochrome P450BM-3

  QS Li; J Ogawa; S Shimizu

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Feb. 2001, Peer-reviewed

  
• Conjugated Linoleic Acid Accumulation via 10-Hydroxy-12-Octadecaenoic Acid during Microaerobic Transformation of Linoleic Acid by Lactobacillus acidophilus

  Jun Ogawa; Kenji Matsumura; Shigenobu Kishino; Yoriko Omura; Sakayu Shimizu

  Applied and Environmental Microbiology, Mar. 2001, Peer-reviewed

  
• Enzymatic production of pyruvate from fumarate - an application of microbial cyclic-imide-transforming pathway

  J Ogawa; CL Soong; M Ito; S Shimizu

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Jan. 2001, Peer-reviewed

  
• Bioelectrocatalytic reduction of dioxygen to water at neutral pH using bilirubin oxidase as an enzyme and 2,2 '-azinobis (3-ethylbenzothiazolin-6-sulfonate) as an electron transfer mediator

  S Tsujimura; B Tatsumi; J Ogawa; S Shimizu; K Kano; T Ikeda

  JOURNAL OF ELECTROANALYTICAL CHEMISTRY, Jan. 2001, Peer-reviewed

  
• 3-Carbamoyl-alpha-picolinic acid production by imidase-catalyzed regioselective hydrolysis of 2,3-pylidinedicarboximide in a water-organic solvent, two-phase system

  J Ogawa; CL Soong; M Ito; T Segawa; T Prana; MS Prana; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Sep. 2000, Peer-reviewed

  
• A novel amidase (half-amidase) for half-amide hydrolysis involved in the bacterial metabolism of cyclic imides

  CL Soong; J Ogawa; S Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, May 2000, Peer-reviewed

  
• beta-Carbon stereoselectivity of N-carbamoyl-D-alpha-amino acid amidohydrolase for alpha,beta-diastereomeric amino acids

  J Ogawa; A Ryono; SX Xie; RM Vohra; R Indrati; H Miyakawa; T Ueno; Y Ikenaka; H Nanba; S Takahashi; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Nov. 1999, Peer-reviewed

  
• Novel bacterial peroxidase without catalase activity from Flavobacterium meningosepticum: purification and characterization

  S Koga; J Ogawa; YM Choi; S Shimizu

  BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, Nov. 1999, Peer-reviewed

  
• Production of 8,11-cis-eicosadienoic acid by a Delta 5 and Delta 12 desaturase-defective mutant derived from the arachidonic acid-producing fungus Mortierella alpina 1S-4

  N Kamada; H Kawashima; E Sakuradani; K Akimoto; U Ogawa; S Shimizu

  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, Nov. 1999, Peer-reviewed

  
• NAD(+)-dependent (S)-specific secondary alcohol dehydrogenase involved in stereoinversion of 3-pentyn-2-ol catalyzed by Norcardia fusca AKU 2123

  SX Xie; J Ogawa; S Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Oct. 1999, Peer-reviewed

  
• Production of (R)3-pentyn-2-ol through stereoinversion of racemic 3-pentyn-2-ol by Nocardia fusca AKU 2123

  SX Xie; J Ogawa; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Sep. 1999, Peer-reviewed

  
• Simultaneous recognition of two chiral centers in alpha,beta-diastereomeric amino acids by an N-carbamoyl-L-alpha-amino acid amidohydrolase from Alcaligenes xylosoxidans

  J Ogawa; A Ryouno; SX Xie; VM Rakesh; R Indrati; H Miyakawa; T Ueno; S Shimizu

  BIOTECHNOLOGY LETTERS, Aug. 1999, Peer-reviewed

  
• Simultaneous recognition of two chiral centers in alpha,beta-diastereomeric amino acids by an N-carbamoyl-L-alpha-amino acid amidohydrolase from Alcaligenes xylosoxidans

  J Ogawa; A Ryouno; SX Xie; VM Rakesh; R Indrati; H Miyakawa; T Ueno; S Shimizu

  BIOTECHNOLOGY LETTERS, Aug. 1999, Peer-reviewed

  
• Coordinate induction of peroxidase and H2O2-forming nucleoside oxidase in Flavobacterium meningosepticum

  S Koga; J Ogawa; YM Choi; S Shimizu

  FEMS MICROBIOLOGY LETTERS, Jun. 1999, Peer-reviewed

  
• Coordinate induction of peroxidase and H2O2-forming nucleoside oxidase in Flavobacterium meningosepticum

  S Koga; J Ogawa; YM Choi; S Shimizu

  FEMS MICROBIOLOGY LETTERS, Jun. 1999, Peer-reviewed

  
• Cyclic-imide-hydrolyzing activity of D-hydantoinase from Blastobacter sp. strain A17p-4

  CL Soong; J Ogawa; M Honda; S Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Apr. 1999, Peer-reviewed

  
• Stereoinversion of optically active 3-pentyn-2-ol by Nocardia species

  J Ogawa; SX Xie; S Shimizu

  BIOTECHNOLOGY LETTERS, Apr. 1999, Peer-reviewed

  
• beta-Carbon stereoselectivity of N-carbamoyl-D-alpha-amino acid amidohydrolase for alpha,beta-diastereomeric amino acids

  J Ogawa; A Ryono; SX Xie; RM Vohra; R Indrati; H Miyakawa; T Ueno; Y Ikenaka; H Nanba; S Takahashi; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Nov. 1999, Peer-reviewed

  
• Stereoinversion of optically active 3-pentyn-2-ol by Nocardia species

  Jun Ogawa; Sheng-Xue Xie; Sakayu Shimizu

  Biotechnology Letters, 1999, Peer-reviewed

  
• Simultaneous recognition of two chiral centers in α, β-diasteremoeric amino acids by┣DBN(/)-┫DB-carbamoyl-L-α-amino acid amiolohydrolase(共著)

  小川 順

  Biotechnol. Lett.,21/,711-713, 1999, Peer-reviewed

  
• Production of (R)3-pentyn-2-ol through stereoinversion of racemic 3-pentyn-2-ol by Nocardia fusca AKU 2123

  SX Xie; J Ogawa; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Sep. 1999, Peer-reviewed

  
• Novel microbial enzymes for the indrstial production of useful compounds : new applications derived from traditional screening

  小川 順

  Trends Biothchnol.,17/,13-21, 1999, Peer-reviewed

  
• Novel bacterial peroxidase without catalase activity from Flavobacterium meningosepticum: purification and characterization

  S Koga; J Ogawa; YM Choi; S Shimizu

  BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, Nov. 1999, Peer-reviewed

  
• Nad+-dependent (s)-specific secondary alcohol dehydrogenase involved in stereoinversion of 3-pentyn-2-ol catalyzed by nocardia fusca AKU 2123

  Sheng-Xue Xie; Jun Ogawa; Sakayu Shimizu

  Bioscience, Biotechnology and Biochemistry, 01 Jan. 1999, Peer-reviewed

  
• Microbial enzymes: new industrial applications from traditional screening methods

  J Ogawa; S Shimizu

  TRENDS IN BIOTECHNOLOGY, Jan. 1999, Peer-reviewed

  
• Production of (R)-3-pentyn-2-ol through stereospecific hydrolysis of racemic 3-pentyn-2-ol esters with microbial enzymes

  J Ogawa; SX Xie; S Shimizu

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Jan. 1999, Peer-reviewed

  
• Production of 8,11,14,17-cis-eicosatetraenoic acid (20 : 4 omega-3) by a Delta 5 and Delta 12 desaturase-defective mutant of an arachidonic acid-producing fungus Mortierella alpina 1S-4

  H Kawashima; E Sakuradani; N Kamada; K Akimoto; K Konishi; J Ogawa; S Shimizu

  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, Nov. 1998, Peer-reviewed

  
• (S)-3-pentyn-2-ol production through microbial enzyme-catalyzed, highly enantioselective hydrolysis of racemic 3-pentyn-2-ol esters

  SX Xie; J Ogawa; S Shimizu

  BIOTECHNOLOGY LETTERS, Oct. 1998, Peer-reviewed

  
• Production of 8,11,14,17-cis-eicosatetraenoic acid (20 : 4 omega-3) by a Delta 5 and Delta 12 desaturase-defective mutant of an arachidonic acid-producing fungus Mortierella alpina 1S-4

  H Kawashima; E Sakuradani; N Kamada; K Akimoto; K Konishi; J Ogawa; S Shimizu

  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, Nov. 1998, Peer-reviewed

  
• Distribution of cyclic imide-transforming activity in microorganisms

  CL Soong; J Ogawa; H Sukiman; T Prana; MS Prana; S Shimizu

  FEMS MICROBIOLOGY LETTERS, Jan. 1998, Peer-reviewed

  
• Nucleoside oxidase, a hydrogen peroxide-forming oxidase, from Flavobacterium meningosepticum

  S Koga; J Ogawa; LY Cheng; YM Choi; H Yamada; S Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Nov. 1997, Peer-reviewed

  
• RNAワールドとDNAワールドを結ぶタンパク質 : リボヌクレオチドレダクターゼ

  小川 順

  生物工学会誌 : seibutsu-kogaku kaishi, 25 Mar. 1997, Peer-reviewed

  
• Diversity and versatility of microbial hydantoin-transforming enzymes

  J Ogawa; S Shimizu

  JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, Feb. 1997, Peer-reviewed

  
• RNAワールドと DNAワールドを結ぶタンパク質：リボヌクレアーゼ

  小川 順

  生物工学, 1997

  
• Ribonucleotide reduetase : a protein liuking RNA-world and DNA-world

  小川 順

  ,75/2,144, 1997, Peer-reviewed

  
• Production of useful fatty acids by microbial processes

  小川 順

  Recent Res. Devel. in Lipids Res.,1/,267-286, 1997, Peer-reviewed

  
• Nucleoside oxidase, a hydrogen peroxide-forming oxidase, from Flavobacterium meningosepticum

  S Koga; J Ogawa; LY Cheng; YM Choi; H Yamada; S Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Nov. 1997, Peer-reviewed

  
• Imidase, a dihydropyrimidinase-like enzyme involved in the metabolism of cyclic imides

  J Ogawa; CL Soong; M Honda; S Shimizu

  EUROPEAN JOURNAL OF BIOCHEMISTRY, Jan. 1997, Peer-reviewed

  
• Novel metabolic transformation pathway for cyclic imides in Blastobacter sp strain A17p-4

  J Ogawa; CL Soong; M Honda; S Shimizu

  APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Oct. 1996, Peer-reviewed

  
• Two extracellar proteins with peroxidase activity from Alkalophilic ┣DBBacillus(/)-┫DB「共著」

  小川 順

  Annual Reports of ICBiotech,, 1996, Peer-reviewed

  
• A new enzymatic method for the measurement of creatinine involving a novel ATP-dependent enzyme, N-methylhydantoin amidohydrolase

  J Ogawa; W Nirdnoy; M Tabata; H Yamada; S Shimizu

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Dec. 1995, Peer-reviewed

  
• Purification and characterization of dihydroorotase from Pseudomonas putida

  J Ogawa; S Shimizu

  ARCHIVES OF MICROBIOLOGY, Nov. 1995, Peer-reviewed

  
• PURIFICATION AND CHARACTERIZATION OF N-CARBAMOYL-L-AMINO ACID AMIDOHYDROLASE WITH BROAD SUBSTRATE-SPECIFICITY FROM ALCALIGENES-XYLOSOXIDANS

  J OGAWA; H MIYAKE; S SHIMIZU

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Nov. 1995, Peer-reviewed

  
• DIVERSITY OF CYCLIC UREIDE COMPOUND, DIHYDROPYRIMIDINE, AND HYDANTOIN HYDROLYZING ENZYMES IN BLASTOBACTER SP A17P-4

  J OGAWA; M HONDA; CL SOONG; S SHIMIZU

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Oct. 1995, Peer-reviewed

  
• NUCLEOSIDE-TRIPHOSPHATASE ACTIVITY OF AN ATP-DEPENDENT ENZYME, N-METHYLHYDANTOIN AMIDOHYDROLASE

  J OGAWA; W NIRDNOY; H YAMADA; S SHIMIZU

  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Sep. 1995, Peer-reviewed

  
• PURIFICATION AND CHARACTERIZATION OF AN ATP-DEPENDENT AMIDOHYDROLASE, N-METHYLHYDANTOIN AMIDOHYDROLASE, FROM PSEUDOMONAS-PUTIDA-77

  J OGAWA; JM KIM; W NIRDNOY; Y AMANO; H YAMADA; S SHIMIZU

  EUROPEAN JOURNAL OF BIOCHEMISTRY, Apr. 1995, Peer-reviewed

  
• Imidase : a new enzyme involved in novel microbial transformation of cyclic imide (共著)

  小川 順

  Annual Reports of ICBiotech,, 1995, Peer-reviewed

  
• THERMOSTABLE N-CARBAMOYL-D-AMINO ACID AMIDOHYDROLASE - SCREENING, PURIFICATION AND CHARACTERIZATION

  J OGAWA; MCM CHUNG; S HIDA; H YAMADA; S SHIMIZU

  JOURNAL OF BIOTECHNOLOGY, Nov. 1994, Peer-reviewed

  
• EVALUATION OF PYRIMIDINE-DEGRADING AND HYDANTOIN-DEGRADING ENZYME-ACTIVITIES IN AEROBIC-BACTERIA

  J OGAWA; T KAIMURA; H YAMADA; S SHIMIZU

  FEMS MICROBIOLOGY LETTERS, Sep. 1994, Peer-reviewed

  
• BETA-UREIDOPROPIONASE WITH N-CARBAMOYL-ALPHA-L-AMINO ACID AMIDOHYDROLASE ACTIVITY FROM AN AEROBIC BACTERIUM, PSEUDOMONAS-PUTIDA IFO 12996

  J OGAWA; S SHIMIZU

  EUROPEAN JOURNAL OF BIOCHEMISTRY, Jul. 1994, Peer-reviewed

  
• Enzymatic asymmetric synthesis of α-methyl arylalkylamines and α-methyl arylalkylalcohols by arylalkyl acylamidases

  Jun Ogawa; Sakayu Shimizu; Hideaki Yamada

  Bioorganic and Medicinal Chemistry, 1994, Peer-reviewed

  
• N-CARBAMOYL-D-AMINO ACID AMIDOHYDROLASE FROM COMAMONAS SP E222C - PURIFICATION AND CHARACTERIZATION

  J OGAWA; S SHIMIZU; H YAMADA

  EUROPEAN JOURNAL OF BIOCHEMISTRY, Mar. 1993, Peer-reviewed

  
• PURIFICATION AND CHARACTERIZATION OF A NOVEL ENZYME, ARYLALKYL ACYLAMIDASE, FROM PSEUDOMONAS-PUTIDA SC2

  S SHIMIZU; J OGAWA; MCM CHUNG; H YAMADA

  EUROPEAN JOURNAL OF BIOCHEMISTRY, Oct. 1992, Peer-reviewed

  
• MICROBIAL ASYMMETRIC HYDROLYSIS OF N-ACETYL-1-METHYL-3-PHENYLPROPYLAMINE TO OPTICALLY-ACTIVE 1-METHYL-3-PHENYLPROPYLAMINE

  S SHIMIZU; J OGAWA; H YAMADA

  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, May 1992, Peer-reviewed

  
• Production of prostaglandin F2α by molecular breeding of an oleaginous fungus Mortierella alpina

  Mohd Fazli, F.A; Y. Shimada; H. Nagano; K. Munesato; M. Takeuchi; M. Takemura; A. Ando; J. Ogawa

  Biosci. Biotechnol. Biochem., Peer-reviewed