Basic Information

Academic Degree

• 博士（医学）(東京大学)
• 修士（医科学）(東京大学)

Research History

• From Sep. 2021, To Present

  Kyoto University Graduate School of Medicine, Department of Pharmacology, Program Specific Senior Lecturer
• From Apr. 2018, To Aug. 2021

  University of Bordeaux, Synaptic Plasticity and Super-Resolution Microcopy (Lab of Valentin Nägerl), ポスドク研究員
• From Apr. 2016, To Jul. 2018

  University of Bordeaux, Synaptic Plasticity and Super-Resolution Microcopy, JSPS fellow
• From Apr. 2013, To Mar. 2016

  RIKEN Brain Science Institute, Developmental Neurobiology (Lab of Katsuhiko Mikoshiba), Special Postodoctoral Researcher
• From Apr. 2012, To Mar. 2013

  RIKEN Brain Science Institute, Developmental Neurobiology (Lab of Katsuhiko Mikoshiba), Postdoctoral researcher

ID,URL

• ORCID ID

  0000-0002-7726-6531

• J-Global ID

  202101002463560001

• Researcher number

  90632927

researchmap URL

• https://researchmap.jp/arizono.misa

Research

Research Interests

• neuron-glia interaction, extracellular space, Ca2+ signals, LLPS, super-resolution microscopy

Research Areas

• Life sciences, Neuroscience - general, Cellular neuroscience, Biophysics

Papers

• Shadow imaging for panoptical visualization of brain tissue in vivo

  Yulia Dembitskaya; Andrew K. J. Boyce; Agata Idziak; Atefeh Pourkhalili Langeroudi; Misa Arizono; Jordan Girard; Guillaume Le Bourdellès; Mathieu Ducros; Marie Sato-Fitoussi; Amaia Ochoa de Amezaga; Kristell Oizel; Stephane Bancelin; Luc Mercier; Thomas Pfeiffer; Roger J. Thompson; Sun Kwang Kim; Andreas Bikfalvi; Valentin Nägerl

  Nature Communications, 12 Oct. 2023

  
• The Impact of Chemical Fixation on the Microanatomy of Mouse Organotypic Hippocampal Slices

  Agata Idziak; V. V. G. Krishna Inavalli; Stéphane Bancelin; Misa Arizono; U. Valentin Nägerl

  eneuro, Sep. 2023

  
• Getting sharper: the brain under the spotlight of super-resolution microscopy

  Misa Arizono; Agata Idziak; Federica Quici; Valentin Nägerl

  Trends in Cell Biology, Feb. 2023

  
• Control of Ca²⁺ signals by astrocyte nanoscale morphology at tripartite synapses

  Audrey Denizot; Misa Arizono; Valentin Nägerl; Hugues Berry; Erik De Schutter

  Glia, Dec. 2022

  
• Super-Resolution Microscopy Opens New Doors to Life at the Nanoscale

  Martin Fuhrmann; Nala Gockel; Misa Arizono; Yulia Dembitskaya; U. Valentin Nägerl; Francesca Pennacchietti; Martina Damenti; Ilaria Testa; Katrin Willig

  The Journal of Neuroscience, 09 Nov. 2022

  
• Deciphering the functional nano-anatomy of the tripartite synapse using stimulated emission depletion microscopy.

  Misa Arizono

  Glia, 19 Oct. 2021

  
• Astrocytic IP₃Rs: Beyond IP₃R2.

  Misa Arizono

  Frontiers in cellular neuroscience, 30 Jul. 2021

  
• Super-resolution shadow imaging reveals local remodeling of astrocytic microstructures and brain extracellular space after osmotic challenge.

  Misa Arizono

  Glia, 12 Mar. 2021

  
• [It takes three to dance tango: Illuminating Ca²⁺ signals at tripartite synapses].

  Misa Arizono

  Medecine sciences : M/S, 16 Feb. 2021

  
• [Thinking outside the cell: Super-resolution shadow imaging (SUSHI) of the extracellular space of the brain].

  Misa Arizono

  Medecine sciences : M/S, 01 Jun. 2020

  
• Structural basis of astrocytic Ca2+ signals at tripartite synapses.

  Misa Arizono

  Nature communications, 20 Apr. 2020

  
• Simulation of calcium signaling in fine astrocytic processes: Effect of spatial properties on spontaneous activity.

  Misa Arizono

  PLoS computational biology, 19 Aug. 2019

  
• Astrocytic IP3 Rs: Contribution to Ca2+ signalling and hippocampal LTP.

  Misa Arizono

  Glia, 07 Jan. 2017, Peer-reviewed

  
• Bidirectional Control of Synaptic GABAAR Clustering by Glutamate and Calcium.

  Misa Arizono

  Cell reports, 17 Dec. 2015, Peer-reviewed

  
• Dissecting tripartite synapses with STED microscopy.

  Misa Arizono

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 01 Oct. 2014

  
• Imaging mGluR5 dynamics in astrocytes using quantum dots.

  Misa Arizono

  Current protocols in neuroscience, 15 Jan. 2014

  
• Spatiotemporal calcium dynamics in single astrocytes and its modulation by neuronal activity.

  Misa Arizono

  Cell calcium, 08 Jan. 2014

  
• Gephyrin-independent GABA(A)R mobility and clustering during plasticity.

  Misa Arizono

  PloS one, 26 Apr. 2012

  
• Receptor-selective diffusion barrier enhances sensitivity of astrocytic processes to metabotropic glutamate receptor stimulation.

  Misa Arizono

  Science signaling, 03 Apr. 2012, Peer-reviewed

  

External funds: Kakenhi

• アストロサイトが束ねるシナプスの働き

  Grant-in-Aid for Challenging Research (Pioneering)

  Medium-sized Section 46:Neuroscience and related fields

  Kyoto University

  有薗 美沙

  From 04 Sep. 2023, To 31 Mar. 2027, Granted

  培養脳スライス;Ca2+イメージング;アストロサイト;シナプス;超解像イメージング

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K18372/

Education

Teaching subject(s)

• From 01 Apr. 2025, To 31 Mar. 2026

  Global Frontier in Life Science A

  1018, Spring, Graduate School of Biostudies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Global Frontier in Life Science A

  1018, Spring, Graduate School of Biostudies, 2