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Kanda, Hiroshi

Graduate School of Biostudies, Division of Systemic Life Science Associate Professor

Kanda, Hiroshi
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    Last Updated :2024/04/02

    Basic Information

    Faculty

    • 薬学部

    Professional Memberships

    • From May 2023, To Present
      日本 cell death 学会
    • From Apr. 2020, To Present
      日本細胞生物学会
    • 日本分子生物学会
    • 日本神経科学会

    Academic Degree

    • (Okayama University)
    • (Osaka University)

    Academic Resume (Graduate Schools)

    • Okayama University, 大学院薬学研究科修士課程医療薬学専攻, 修了
    • Osaka University, 大学院医学系研究科博士課程情報伝達医学専攻, 修了

    Academic Resume (Undergraduate School/Majors)

    • Okayama University, 薬学部製薬化学科, 卒業

    Research History

    • From Apr. 2023, To Present
      Kyoto University, 薬学部多細胞システム学分野(分野名変更), 准教授(兼任)
    • From Oct. 2019, To Mar. 2023
      Kyoto University, 薬学部生理活性制御学分野, Associate Professor
    • From Oct. 2019, To Present
      Kyoto University, Laboratory of Genetics, Graduate School of Biostudies, Associate Professor
    • From Apr. 2019, To Mar. 2022
      Tokyo Online University, Department of Human Welfare, 非常勤講師(兼任)
    • From Oct. 2016, To Sep. 2019
      慶應義塾大学, 医学部・生理学, 専任講師
    • From Dec. 2016, To Mar. 2019
      京都大学, 大学院薬学系研究科, 非常勤講師(兼任)
    • From 01 Mar. 2008, To 30 Sep. 2016
      慶應義塾大学, 医学部・生理学, 助教
    • From Sep. 2012, To Mar. 2013
      神戸大学, 大学院医学系研究科, 非常勤講師(兼任)
    • From Apr. 2005, To Feb. 2008
      カリフォルニア大学バークレー校, ポスドク
    • From Apr. 2005, To Mar. 2007
      日本学術振興会, 海外特別研究員
    • From Apr. 2002, To Mar. 2005
      日本学術振興会, 特別研究員 (DC1)
    • From Apr. 1999, To Mar. 2001
      薬剤師

    ID,URL

    researchmap URL

    list
      Last Updated :2024/04/02

      Research

      Research Topics, Overview of the research

      • Research Topics

        Elucidation and control of cell competition
      • Overview of the research

        Cell competition is a context-dependent cell elimination whereby cells with higher fitness eliminate neighboring cells with lower fitness by inducing cell death. Cell competition not only regulates the tissue homeostasis, for example by maintaining stem cell pool, but also protects tissue from tumorigenesis via cell-cell communication. We are dissecting the unexpectedly diverse physiological significance and its regulatory basis of cell competition by using powerful Drosophila genetics.

      Research Interests

      • cell competition
      • がん
      • ショウジョウバエ
      • 遺伝学
      • 血液脳関門
      • neural stem cells

      Research Areas

      • Life sciences, Tumor biology
      • Life sciences, Developmental biology
      • Life sciences, Neuroscience - general

      Papers

      • Mechanism of tumor‐suppressive cell competition in flies
        Hiroshi Kanda; Tatsushi Igaki
        Cancer Science, 17 Jul. 2020, Peer-reviewed, Invited, Lead author
      • Degradation of Extracellular Matrix by Matrix Metalloproteinase 2 Is Essential for the Establishment of the Blood-Brain Barrier in Drosophila
        Hiroshi Kanda; Rieko Shimamura; Michiko Koizumi-Kitajima; Hideyuki Okano
        iScience, 28 Jun. 2019, Peer-reviewed, Lead author, Corresponding author
      • Musashi mediates translational repression of the Drosophila hypoxia inducible factor
        Agustina P. Bertolin; Maximiliano J. Katz; Masato Yano; Berta Pozzi; Julieta M. Acevedo; Dalmiro Blanco-Obregon; Lautaro Gandara; Eleonora Sorianello; Hiroshi Kanda; Hideyuki Okano; Anabella Srebrow; Pablo Wappner
        NUCLEIC ACIDS RESEARCH, Sep. 2016, Peer-reviewed
      • The Drosophila Ortholog of MLL3 and MLL4, trithorax related, Functions as a Negative Regulator of Tissue Growth
        Hiroshi Kanda; Alexander Nguyen; Leslie Chen; Hideyuki Okano; Iswar K. Hariharan
        MOLECULAR AND CELLULAR BIOLOGY, May 2013, Peer-reviewed, Lead author
      • Conserved metabolic energy production pathways govern Eiger/TNF-induced nonapoptotic cell death
        Hiroshi Kanda; Tatsushi Igaki; Hideyuki Okano; Masayuki Miura
        PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Nov. 2011, Peer-reviewed, Lead author
      • Regenerative Growth in Drosophila Imaginal Discs Is Regulated by Wingless and Myc
        Rachel K. Smith-Bolton; Melanie I. Worley; Hiroshi Kanda; Iswar K. Hariharan
        DEVELOPMENTAL CELL, Jun. 2009, Peer-reviewed
      • Tumor suppressor CYLD regulates JNK-Induced cell death in Drosophila
        Lei Xue; Tatsushi Igaki; Erina Kuranaga; Hiroshi Kanda; Masayuki Miura; Tian Xu
        DEVELOPMENTAL CELL, Sep. 2007, Peer-reviewed
      • Capicua regulates cell proliferation downstream of the receptor tyrosine kinase/Ras signaling pathway
        Ai-Sun Kelly Tseng; Nicolas Tapon; Hiroshi Kanda; Seden Cigizoglu; Lambert Edelmann; Brett Pellock; Kristin White; Iswar K. Hariharan
        CURRENT BIOLOGY, Apr. 2007, Peer-reviewed
      • Relationships of Drosophila melanogaster RECQS/QE to cell-cycle progression and DNA damage
        Minoru Nakayama; Sayako Maruyama; Hiroshi Kanda; Noriko Ohkita; Katsunori Nakano; Fumiaki Ito; Katsumi Kawasaki
        FEBS LETTERS, Dec. 2006, Peer-reviewed
      • Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity.
        Kanuka H; Hiratou T; Igaki T; Kanda H; Kuranaga E; Sawamoto K; Aigaki T; Okano H; Miura M
        Biochimica et biophysica acta, 03 Nov. 2005, Peer-reviewed
      • Gain-of-function screen identifies a role of the Sec61 alpha translocon in Drosophila postmitotic neurotoxicity
        H Kanuka; T Hiratou; T Igaki; H Kanda; E Kuranaga; K Sawamoto; T Aigaki; H Okano; M Miura
        BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, Nov. 2005, Peer-reviewed
      • Regulatory roles of JNK in programmed cell death
        H Kanda; M Miura
        JOURNAL OF BIOCHEMISTRY, Jul. 2004, Peer-reviewed, Lead author
      • Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling
        H Kanda; T Igaki; H Kanuka; T Yagi; M Miura
        JOURNAL OF BIOLOGICAL CHEMISTRY, Aug. 2002, Peer-reviewed, Lead author
      • Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway
        T Igaki; H Kanda; Y Yamamoto-Goto; H Kanuka; E Kuranaga; T Aigaki; M Miura
        EMBO JOURNAL, Jun. 2002, Peer-reviewed
      • Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by dark and DRONC
        T Igaki; Y Yamamoto-Goto; N Tokushige; H Kanda; M Miura
        JOURNAL OF BIOLOGICAL CHEMISTRY, Jun. 2002, Peer-reviewed
      • Antitumor mechanisms and metabolism of the novel antitumor nucleoside analogues, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and 1-(3-C-ethynyl-beta-D- ribo-pentofuranosyl)uracil
        S Takatori; H Kanda; K Takenaka; Y Wataya; A Matsuda; M Fukushima; Y Shimamoto; M Tanaka; T Sasaki
        CANCER CHEMOTHERAPY AND PHARMACOLOGY, Aug. 1999, Peer-reviewed
      • The characterization of cell death induced by 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyD) in FM3A cells
        S Takatori; S Tsutsumi; M Hidaka; H Kanda; A Matsuda; M Fukushima; Y Wataya
        NUCLEOSIDES & NUCLEOTIDES, 1998, Peer-reviewed

      Misc.

      • 細胞競合を制御する分子機構
        菅田浩司; 井垣達吏
        医学のあゆみ, Oct. 2022, Lead author
      • Post-translational regulation of Musashi1 RNA-binding activity and its translational control
        Takao Imai; Hiroshi Kanda; Hironori Kawahara; Satoshi Kawase; Hideyuki Okano
        NEUROSCIENCE RESEARCH, 2008
      • 休止期神経幹細胞の再活性化機構
        菅田浩司
        ブレインサイエンス・レビュー2020, 20 Mar. 2020, Lead author, Corresponding author
      • 4D 蛍光イメージングのためのライトシート顕微鏡
        菅田浩司; 岡野栄之
        Medical Science Digest, 25 Aug. 2015, Lead author
      • ショウジョウバエを用いた血液脳関門機能の遺伝学的解析
        菅田浩司; 岡野栄之
        細胞工学, 22 Aug. 2013, Lead author
      • Eiger and Wengen: The Drosophila Orthologs of TNF/TNFR
        Tatsushi Igaki; Hiroshi Kanda; Hideyuki Okano; Tian Xu; Masayuki Miura
        ADVANCES IN TNF FAMILY RESEARCH, 2011
      • 細胞死制御を応用した組織再生モデル系の構築
        菅田浩司
        実験医学増刊, 01 May 2010, Lead author, Corresponding author
      • Agenetic approach for the organization and function of the blood brain barrier in Drosophila
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        NEUROSCIENCE RESEARCH, 2010
      • Cell death execution mechanisms in Drosophila.
        Kanda H; Igaki T; Kuranaga E; Kanuka H; Miura M
        RIKEN Review, 2001
      • The characterization of cell death induced by 1-(3-C-ethynyl-b-D-ribo-pento-furanosyl) cytosine (ECyd) and 1-(3-C-ethynyl- b-D-ribo-pento-furanosyl) uridine (EUrd)
        Kanda H; Takatori S; Matsuda A; Sasaki T; Tanaka M; Fukushima M; Wataya Y
        Nucleic Acids Symposium Series, 1997

      Presentations

      • 細胞競合を介したRas/scrib腫瘍制御機構の遺伝学的解析
        西山真生; 菅田浩司; 井垣達吏
        第11回細胞競合コロキウム, 05 Mar. 2024
      • Regulation of cell competition by ribosome
        Hiroshi Kanda; Aya Kawasaki; Shu Kondo; Kuniaki Saito; Tomoe Kobayashi; Makoto Matsuyama; Tatsushi Igaki
        3rd Reaearch Networking Salon, 27 Sep. 2023
      • The cell fate of Ras/scrib clone is regulated by cell number
        Masaki Nishiyama; Hiroshi Kanda; Tatsushi Igaki
        3rd Reaearch Networking Salon, 27 Sep. 2023
      • A genetic screen for key regulators of cell competition
        Mai Sakaguchi; Hiroshi Kanda; Tatsushi Igaki
        3rd Reaearch Networking Salon, 27 Sep. 2023
      • A genetic screen for core mechanism and physiological triggers of cell competition
        Ryo Matsumoto; Hiroshi Kanda; Aya Kawasaki; Mai Nakamura; Rina Nagata; Naotaka Ochi; Ayumu Okumura; Xinyue Huang; Naoki Wakasa; Yohji Noguchi; Ryosuke Nakano; Tomoe Kobayashi; Makoto Matsuyama; Tatsushi Igaki
        3rd Reaearch Networking Salon, 27 Sep. 2023
      • A genetic screen and characterization of triggers of cell competition
        Hiroshi Kanda; Ryo Matsumoto; Aya Kawasaki; Mai Nakamura; Rina Nagata; Xinyue Huang; Ayumu Okumura; Naotaka Ochi; Yoji Noguchi; Naoki Wakasa; Ryosuke Nakano; Tatsushi Igaki
        Japan and Australia Meeting on Cell Death 2023, 17 Aug. 2023
      • 細胞競合はリボソームタンパク質 RpS27A によって制御される
        菅田浩司; 川﨑あや; 近藤周; 齋藤都暁; 小林朋絵; 松山誠; 井垣達吏
        多細胞生命自律性第3回領域班会議, 06 Sep. 2023
      • 細胞競合のコアメカニズムと生理的トリガーの遺伝学的探索
        松本涼; 菅田浩司; 川﨑あや; 中村麻衣; 永田理奈; 越智直孝; 黄新月; 奥村歩; 若狭直樹; 野口耀司; 中野吏洋助; 小林朋絵; 松山誠; 井垣達吏
        多細胞生命自律性第3回領域班会議, 06 Sep. 2023
      • 細胞競合を駆動する分子機構の遺伝学的解析
        川﨑あや; 菅田浩司; 永田理奈; 小林 朋絵; 松山 誠; 井垣達吏
        多細胞生命自律性第3回領域班会議, 06 Sep. 2023
      • Ras/scrib 腫瘍の細胞数依存的な運命制御機構の解析
        西山真生; 菅田浩司; 井垣達吏
        多細胞生命自律性第3回領域班会議, 06 Sep. 2023
      • 細胞競合をトリガーする細胞状態センサーの探索
        菅田浩司; 川﨑あや; 近藤周; 齋藤都暁; 小林朋絵; 松山誠; 井垣達吏
        第31回日本Cell Death学会学術集会, 15 Jul. 2023
      • 細胞競合の共通メカニズムと生理的トリガーの遺伝学的探索
        松本涼; 菅田浩司; 川﨑あや; 中村麻衣; 永田理奈; 越智直孝; 黄新月; 奥村歩; 若狭直樹; 野口耀司; 中野吏洋介; 小林朋絵; 松山誠; 井垣達吏
        第75回日本細胞生物学会大会, 30 Jun. 2023
      • 細胞競合を駆動する分子機構の遺伝学的解析
        川﨑あや; 菅田浩司; 永田理奈; 小林朋絵; 松山誠; 井垣達吏
        第75回日本細胞生物学会大会, 30 Jun. 2023
      • 細胞数依存的なRas/scrib腫瘍の運命制御機構
        西山真生; 菅田浩司; 井垣達吏
        第10回細胞競合コロキウム, 15 Mar. 2023
      • リボソームタンパク質による細胞競合制御の遺伝学的解析
        菅田浩司; 川﨑あや; 近藤周; 齋藤都暁; 小林朋絵; 松山誠; 井垣達吏
        第10回細胞競合コロキウム, 14 Mar. 2023
      • A genetic screen and characterization of triggers of cell competition.
        Hiroshi Kanda; Ryo Matsumoto; Aya Kawasaki; Mai Nakamura; Rina Nagata; Xinyue Huang; Ayumu Okumura; Naotaka Ochi; Yoji Noguchi; Naoki Wakasa; Ryosuke Nakano; Tatsushi Igaki
        64th Annual Drosophila Research Conference, 01 Mar. 2023
      • リボソームタンパク質による細胞競合制御の遺伝学的解析
        菅田浩司; 川﨑あや; 近藤周; 齋藤都暁; 小林朋絵; 松山誠; 井垣達吏
        第2回多細胞生命自律性班会議, 14 Dec. 2022
      • Ras/scrib細胞は細胞競合のloserとしてふるまう
        西山 真生; 菅田 浩司; 井垣 達吏
        第2回多細胞生命自律性班会議, 14 Dec. 2022
      • リボソームタンパク質による細胞競合制御の遺伝学的解析
        菅田浩司; 川﨑あや; 近藤周; 齋藤都暁; 小林朋絵; 松山誠; 井垣 達吏
        第45回日本分子生物学会年会, 02 Dec. 2022
      • ⼩胞体ストレスが誘導する細胞競合の遺伝学的解析
        川﨑あや、菅田浩司、小林朋絵、松山誠、井垣達吏
        第45回日本分子生物学会年会, 02 Dec. 2022
      • Genetic analysis of ER stress-induced cell competition
        Aya Kawasaki; Hiroshi Kanda; Tomoe Kobayashi; Makoto Matsuyama; Tatsushi Igaki
        第15回日本ショウジョウバエ研究会, 12 Sep. 2022
      • Regulation of cell competition by the ribosome
        Hiroshi Kanda; Aya Kawasaki; Shu Kondo; Kuniaki Saito; Tomoe Kobayashi; Makoto Matsuyama; Tatsushi Igaki
        第15回日本ショウジョウバエ研究会, 12 Sep. 2022
      • Regenerative growth in Drosophila imaginal discs is regulated by Wg and Myc.
        Rachel K. Smith-Bolton; Melanie Worley; Hiroshi Kanda; Iswar K. Hariharan
        50th Annual Drosophila Research Conference, 07 Mar. 2009
      • Regulation of regenerative growth in imaginal discs.
        Rachel K. Smith-Bolton; Melanie Worley; Hiroshi Kanda; Iswar Hariharan
        Santa Cruz Developmental Biology Meeting, 27 Jun. 2008
      • Regulation of regenerative growth in imaginal discs.
        Rachel K. Smith-Bolton; Melanie Worley; Hiroshi Kanda; Iswar Hariharan
        49th Annual Drosophila Research Conference, 03 Apr. 2008
      • 抗腫瘍性ヌクレオシド 3’-ethynylcytidine (ECyd)、及び 3’-ethynyluridine (EUrd)の作用機序の解析
        武中輝世子; 菅田浩司; 高取聡; 松田彰; 佐々木琢磨; 田中基裕; 横川達史; 綿矢有佑; 福島正和
        第3回がん分子標的治療研究会総会, 04 Jun. 1999
      • 抗腫瘍性ヌクレオシド 3’-ethynylcytidine (ECyd)がマウス乳癌由来 FM3A 細胞に誘導する RNA 断片化の分子機構.
        横川達史; 菅田浩司; 高取聡; 松田彰; 佐々木琢磨; 田中基裕; 横川達史; 綿矢有佑; 福島正和
        第3回がん分子標的治療研究会総会, 04 Jun. 1999
      • 多機能化新規抗腫瘍性ヌクレオシド、エチニルシチジン (ECyd)、及びエチニルウリジン (EUrd)の作用機序の解析
        高取聡; 増井修; 菅田浩司; 綿矢有佑; 松田彰; 佐々木琢磨; 田中基裕; 福島正和
        第55回日本癌学会学術総会, 10 Oct. 1996
      • 細胞競合を駆動する分子機構の遺伝学的解析
        川﨑あや; 菅田浩司; 井垣達吏
        第74回細胞生物学会, 30 Jun. 2022
      • 細胞競合の共通メカニズムと生理的トリガーの遺伝学的探索
        松本涼; 菅田浩司; 川﨑あや; 中村麻衣; 永田理奈; 越智直孝; 黄新月; 奥村歩; 若狭直樹; 野口耀司; 中野吏洋助; 井垣達吏
        第74回細胞生物学会, 30 Jun. 2022
      • 細胞競合を誘導する細胞内変化を司る分子機構の遺伝学的解析
        菅田浩司; 川﨑あや; 奥村歩; 井垣達吏
        第74回細胞生物学会, 30 Jun. 2022
      • 細胞競合を駆動する分子機構の遺伝学的解析
        川﨑あや; 菅田浩司; 井垣達吏
        第9回細胞死コロキウム, 14 Mar. 2022
      • 細胞競合を駆動する分子基盤の遺伝学的解析
        菅田浩司; 川﨑あや; 井垣達吏
        第9回細胞競合コロキウム, 14 Mar. 2022
      • Surveying the cell competition landscape by a Drosophila genetic screen
        Ryo Matsumoto; Xinyue Huang; Hiroshi Kanda; Aya Kawasaki; Ayumu Okumura; Mai Nakamura; Naotaka Ochi; Rina Nagata; Yoji Noguchi; Naoki Wakasa; Ryosuke Nakano; Tatsushi Igaki
        62nd Annual Drosophila Research Conference, Mar. 2021
      • A genetic screen in Drosophila for the molecular basis of cell competition
        Hiroshi Kanda; Ayumu Okumura; Aya Kawasaki; Mai Nakamura; Ryosuke Nakano; Naoki Wakasa; Tatsushi Igaki
        The 43th Annual Meeting of Molecular Biology Society of Japan, 04 Dec. 2020
      • A genetic approach for the molecular basis of cell competition.
        菅田浩司; 中村麻衣; 中野吏洋助; 若狭直樹; 松本涼; 黄新月; 井垣達吏
        The 72nd Annual Meeting of the Japanese Society for Cell Biology, Jun. 2020
      • Evolutionarily conserved molecules regulate the integrity of Blood-Brain Barrier in Drosophila
        Kanda H; Shimamura R; Koizumi-Kitajima M; Hideyuki Okano
        第42回日本神経科学大会, Jul. 2019
      • 血液脳関門の普遍原理の解析
        菅田 浩司
        第2回淡路ショウジョウバエ研究会, Oct. 2018, Invited
      • A genetic approach for the understanding of the brain micro-environment that regulates the plasticity of neural stem cells.
        Kanda H; T. Yamaguchi; R. Shimamura; Sugiura Y; Honda K; Suematsu M; Yoshinari Y; Niwa R; H. Okano
        59th Annual Drosophila Research Conference, Apr. 2018
      • 神経幹細胞の可塑性を制御する分子基盤の解明
        菅田 浩司
        第1回淡路ショウジョウバエ研究会, Oct. 2017, Invited
      • A genetic approach for the understanding of the brain microenvironment that regulates the plasticity of neural stem cells.
        Hiroshi Kanda; Taro Yamaguchi; Rieko Shimamura; Hideyuki Okano
        25th European Drosophila Research Conference, Sep. 2017
      • Brain micro environment regulates the plasticity of neural stem cells.
        Hiroshi Kanda; Rieko Shimamura; Taro Yamaguchi; Michiko Kitajima; Hideyuki Okano
        第40回日本神経科学大会, Jul. 2017
      • Why brain needs to be isolated?
        Kanda, Hiroshi
        直感から紐解く生命現象の理解, Mar. 2017, Invited
      • A genetic approach for the understanding of the brain environment that regulates the plasticity of neural stem cells.
        Hiroshi Kanda; Rieko Shimamura; Taro Yamaguchi; Michiko Kitajima; Hideyuki Okano
        第39回日本神経科学大会, Jul. 2016
      • 血液脳関門の普遍原理の解析
        菅田 浩司
        グローバルサイエンスキャンパスプログラム, 14 May 2016, Invited
      • Evolutionarily conserved function of Blood-Brain Barrier.
        Kanda, Hiroshi
        Chronological Change in Brain Function, 08 Mar. 2016, Invited
      • 神経幹細胞の可塑性を制御する分子機構
        菅田浩司; 島村理恵子; 岡野栄之
        第11回成体脳のニューロン新生懇談会, Nov. 2015
      • A genetic approach for understanding the plasticity of neural stem cells in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Michiko O. Inouye; Hideyuki Okano
        第38回日本神経科学大会, Jul. 2015
      • モデル生物を用いた神経幹細胞の可塑性を規定する分子基盤の解析
        菅田浩司; 島村理恵子; 山口太朗; 井上通子; 岡野栄之
        第14回日本再生医療学会総会, Mar. 2015
      • in vivo RNAi-based approach for the integrity of the Blood-Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        18th International Vascular Biology Meeting (IVBM 2014), Apr. 2014
      • Evolutionarily conserved molecule regulates the integrity of Blood-Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        第36回日本神経科学大会, Jun. 2013
      • MLL family proteins differently regulate cell growth and survival in Drosophila
        Hiroshi Kanda; Alexander Nguyen; Hideyuki Okano; Iswar Hariharan
        第35回日本分子生物学会年会, Dec. 2012
      • Identification of genes required for the integrity of Blood-Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        Neuro-Vascular Wiring Symposium 2012, Nov. 2012
      • RNAi-based genetic screen of genes required for the integrity of the Blood-Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        10th Japan Drosophila Research Conference, Oct. 2012
      • A genetic approach for the organization and function of the Blood-Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        The 4th Biennial Symposium on Brain and Mind Research in the Asia-Pacific (BMAP2012), Aug. 2012
      • Conserved metabolic energy production pathways govern Eiger/TNF-induced non-apoptotic cell death
        Hiroshi Kanda; Tatsushi Igaki; Hideyuki Okano; Masayuki Miura
        第34回日本分子生物学会年会, Dec. 2011
      • A genetic approach for the organization and function of the Blood Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        第34回日本神経科学大会, Sep. 2011
      • A Genetic Approach for the Organization and Function of the Blood-Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        The 1st Asia Pacific Drosophila Research Conference, Jun. 2011
      • A genetic approach for the organization and function of the Blood-Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        Cold Spring Harbor Laboratories Meeting, Dec. 2010
      • A genetic approach for the organization and function of the Blood-Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        International Conference of the International Society of Differentiation, Nov. 2010
      • A genetic approach for the organization and function of the Blood Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        第33回日本神経科学大会, Sep. 2010
      • in vivo large scale screen to identify molecules that regulate the integrity of Blood-Brain Barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        第32回日本分子生物学会年会, Dec. 2009
      • A genetic approach for the organization and function of the blood brain barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        慶應ニューロサイエンス研究会, Oct. 2009
      • Genetic analysis of the organization and function of the blood brain barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        第32回日本神経科学大会, Sep. 2009
      • A genetic approach for the organization and function of the blood brain barrier in Drosophila.
        Hiroshi Kanda; Rieko Shimamura; Hideyuki Okano
        9th Japan Drosophila Research Conference, Jul. 2009
      • A genetic screen for regulators of cell growth and proliferation.
        Hiroshi Kanda; Alexander H. Nguyen; Leslie Chen; Iswar K. Hariharan
        50th Annual Drosophila Research Conference, Mar. 2009
      • A genetic screen for regulators of cell growth and proliferation in Drosophila.
        Kanda, Hiroshi
        COEX meeting, 16 May 2008, Invited
      • ショウジョウバエ TNF スーパーファミリー分子 Eiger により誘導される神経細胞死はミトコンドリアを介した経路により実行される
        菅田浩司; 井垣達吏; 松田七美; 三浦正幸
        第27回日本分子生物学会年会, Dec. 2004
      • ショウジョウバエ TNF スーパーファミリー分子 Eiger による細胞死の分子機構の解析
        菅田浩司; 井垣達吏; 三浦正幸
        第26回日本分子生物学会年会, Dec. 2003
      • ショウジョウバエ TNF スーパーファミリー分子 Eiger による細胞死実行機構の遺伝学的解析
        菅田浩司; 井垣達吏; 三浦正幸
        第239回日本生理学会東京談話会, Oct. 2003
      • Identification and Characterization of Downstream Molecules of Eiger, a Drosophila TNF Superfamily Protein.
        Hiroshi Kanda; Jun Takahashi; Tatsushi Igaki; Hiroka Aonuma; Nanami Matsuda; Erina Kuranaga; Miura M
        Cold Spring Harbor Laboratory Meetings, Sep. 2003
      • A genetic screen for downstream molecules of Drosophila TNF superfamily protein, Eiger
        Hiroshi Kanda; Tatsushi Igaki; Masayuki Miura
        6th Japan Drosophila Research Conference, Jul. 2003
      • A genetic screen for downstream molecules of Drosophila TNF superfamily protein, Eiger
        Hiroshi Kanda; Tatsushi Igaki; Masayuki Miura
        第25回日本分子生物学会年会, Dec. 2002
      • Identification of a Novel Cell Death Regulator by a Drosophila Misexpression Screen.
        Tatsushi Igaki; Hiroshi Kanda; Yuki Goto; Hirotaka Kanuka; Toshiro Aigaki; Masayuki
        Cold Spring Harbor Laboratory Meetings, Nov. 2001
      • A genetic screen for downstream molecules of Eiger
        Hiroshi Kanda; Tatsushi Igaki; Yuki Yamamoto-Goto; Hirotaka Kanuka; Toshiro Aigaki; Masayuki Miura
        第24回日本分子生物学会年会, Aug. 2001
      • Cytotoxic mechanisms of new antitumor nucleoside analogues, 3’-ethynilcytidine (ECyd) and 3’-ethynyluridine (EUrd).
        菅田浩司; 高取聡; 松田彰; 佐々木琢磨; 田中基裕; 福島正和; 綿矢有佑
        第2回癌分子標的治療研究会, Jun. 1998
      • 抗腫瘍性ヌクレオシド 3’-ethynylcytidine (ECyd)、及び 3’-ethynyluridine (EUrd)の作用機序の解析
        菅田浩司; 高取聡; 堤信二; 日高宗明; 綿矢有佑
        第24回核酸化学シンポジウム, Nov. 1997
      • 新規抗腫瘍性ヌクレオシド 3’-ethynylcytidine (ECyd)、及び 3’-ethynyluridine (EUrd)の作用機序の解析)
        菅田浩司; 高取聡; 松田彰; 田中基裕; 佐々木琢磨; 福島正和; 綿矢有佑
        第55回日本癌学会総会, Oct. 1997

      Awards

      • Jun. 2014
        慶應義塾大学医学部, 三四会奨励賞

      External funds: Kakenhi

      • A genetic approach for the regulation of cell competition.
        Grant-in-Aid for Scientific Research (B)
        Basic Section 44010:Cell biology-related
        Kyoto University
        菅田 浩司
        From 01 Apr. 2021, To 31 Mar. 2024, Granted
        ショウジョウバエ;細胞競合;がん;遺伝学;がん悪性化;悪性腫瘍
      • A genetic approach for the mechanism of tumor malignancy in Drosophila.
        Grant-in-Aid for Challenging Research (Exploratory)
        Medium-sized Section 50:Oncology and related fields
        Kyoto University
        Hiroshi Kanda
        From 30 Jul. 2020, To 31 Mar. 2023, Project Closed
        ショウジョウバエ;がん悪性化;遺伝学;腫瘍悪性化;複眼原基;スクリーニング
      • A genetic approach for the understanding of the brain micro-environment that regulates the plasticity of neural stem cells
        Grant-in-Aid for Scientific Research (C)
        Keio University
        Hiroshi KANDA
        From 01 Apr. 2017, To 31 Mar. 2020, Project Closed
        ショウジョウバエ;神経幹細胞;Neuroblast;再活性化;可塑性;遺伝学;neuroblast;神経科学
      • A genetic approach for the understanding of the integrity of Blood-Brain Barrier in Drosophila.
        Grant-in-Aid for Challenging Exploratory Research
        Keio University
        Hiroshi KANDA
        From 01 Apr. 2014, To 31 Mar. 2017, Project Closed
        血液脳関門;遺伝学;ショウジョウバエ;BBB
      • 脳内環境を制御する神経幹細胞の恒常性変化
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Keio University
        菅田 浩司
        From 01 Apr. 2014, To 31 Mar. 2016, Project Closed
        ショウジョウバエ;脳内環境;神経幹細胞;遺伝学;神経;可塑性;neuroblast;再活性化
      • 血液脳関門のワイヤリング形成における静的秩序獲得機構
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Keio University
        菅田 浩司
        From 01 Apr. 2013, To 31 Mar. 2015, Project Closed
        ショウジョウバエ;血液脳関門;遺伝学;BBB
      • The molecular basis of the Blood-Brain Barrier
        Grant-in-Aid for Young Scientists (B)
        Keio University
        Hiroshi KANDA
        From 01 Apr. 2011, To 31 Mar. 2013, Project Closed
        血液脳関門;BBB;ショウジョウバエ;遺伝学;グリア;スクリーニング;RNAi
      • 細胞間ワイヤリングを基軸とする血液脳関門の制御機構
        Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
        Biological Sciences
        Keio University
        菅田 浩司
        From 01 Apr. 2011, To 31 Mar. 2013, Project Closed
        ショウジョウバエ;血液脳関門;遺伝学;BBB;スクリーニング
      • A genetic approach for the neuronal cell fate determination in Drosophila.
        Grant-in-Aid for Young Scientists (Start-up)
        Keio University
        Hiroshi KANDA
        From 01 Apr. 2008, To 31 Mar. 2010, Project Closed
        神経;スクリーニング;ショウジョウバエ;遺伝学;Musashi;SOP

      External funds: others

      • 休止期神経幹細胞の再活性化機構の解明
        公益財団法人ブレインサイエンス振興財団・研究助成金
        From 2014, To 2014
        菅田浩司
      • 血液脳関門の強度を規定する分子機構の解明
        公益財団法人稲盛財団・研究助成金
        From 2014, To 2014
        菅田浩司
      • 進化的に保存された血液脳関門の分子機構の解明
        公益財団法人かなえ医薬振興財団・研究助成金
        From 2013, To 2013
        菅田浩司
      • 血液脳関門の強度を規定する因子の遺伝学的解析
        公益財団法人三菱財団・自然科学研究助成
        From 2012, To 2012
        菅田浩司
      • 血液脳関門を制御する分子機構の遺伝学的解析
        公益財団法人持田記念医学薬学振興財団・研究助成金
        From 2012, To 2012
        菅田浩司
      • 血液脳関門の恒常性維持機構に関する遺伝学的解析
        公益財団法人武田科学振興財団・医学系研究奨励
        From 2012, To 2012
        菅田浩司
      list
        Last Updated :2024/04/02

        Education

        Teaching subject(s)

        • From 01 Apr. 2023, To 31 Mar. 2024
          ILAS Seminar
          Z001, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Introduction to Biology and Life Science
          N484, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Course in Studies on Signal Transduction
          1029, Fall, Graduate School of Biostudies, 1
        • From 01 Apr. 2023, To 31 Mar. 2024
          Pharmaceutical Laboratory IV : Biochemistry and Microbiology
          C906, Fall, Faculty of Pharmaceutical Sciences, 3
        • From 01 Apr. 2023, To 31 Mar. 2024
          Experimental Course and Seminar D
          2009, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Experimental Course and Seminar D
          2009, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Experimental Course and Seminar C
          2008, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Experimental Course and Seminar A
          2006, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Experimental Course and Seminar A
          2006, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Experimental Course and Seminar C
          2008, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Experimental Course and Seminar B
          2007, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Experimental Course and Seminar B
          2007, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2023, To 31 Mar. 2024
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          A906, Fall, Faculty of Pharmaceutical Sciences, 4
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Experiments in Systemic Life Sciences
          5013, Spring, Graduate School of Biostudies, 4
        • From 01 Apr. 2023, To 31 Mar. 2024
          Advanced Experiments in Systemic Life Sciences
          5013, Fall, Graduate School of Biostudies, 4
        • From 01 Apr. 2023, To 31 Mar. 2024
          Biological Chemistry V (Cell Biology)
          C205, Fall, Faculty of Pharmaceutical Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Biological Chemistry 5 (Cell Biology)
          A205, Fall, Faculty of Pharmaceutical Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Introduction to Pharmaceutical Biochemistry
          8103, Spring, Graduate School of Pharmaceutical Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Introduction to Pharmaceutical Sciences
          6002, Spring, Graduate School of Pharmaceutical Sciences, 2
        • From 01 Apr. 2023, To 31 Mar. 2024
          Introduction to Modern Life Sciences for Drug Discovery
          1027, Spring, Graduate School of Pharmaceutical Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar A
          2006, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Introduction to Pharmaceutical Biochemistry
          8103, Spring, Graduate School of Pharmaceutical Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Pharmaceutical Laboratory IV : Biochemistry and Microbiology
          C906, Fall, Faculty of Pharmaceutical Sciences, 3
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar C
          2008, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar B
          2007, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Experiments in Systemic Life Sciences
          5013, Fall, Graduate School of Biostudies, 4
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Course in Studies on Signal Transduction
          1029, Fall, Graduate School of Biostudies, 1
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar A
          2006, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Advanced Experiments in Systemic Life Sciences
          5013, Spring, Graduate School of Biostudies, 4
        • From 01 Apr. 2022, To 31 Mar. 2023
          ILAS Seminar
          Z001, Spring, Institute for Liberal Arts and Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar C
          2008, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar D
          2009, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar B
          2007, Fall, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          A906, Fall, Faculty of Pharmaceutical Sciences, 4
        • From 01 Apr. 2022, To 31 Mar. 2023
          Biological Chemistry V (Cell Biology)
          C205, Fall, Faculty of Pharmaceutical Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Introduction to Modern Life Sciences for Drug Discovery
          1027, Spring, Graduate School of Pharmaceutical Sciences, 2
        • From 01 Apr. 2022, To 31 Mar. 2023
          Experimental Course and Seminar D
          2009, Spring, Graduate School of Biostudies, 5
        • From 01 Apr. 2022, To 31 Mar. 2023
          Biological Chemistry 5 (Cell Biology)
          A205, Fall, Faculty of Pharmaceutical Sciences, 2
        • From Apr. 2020, To Mar. 2021
          ILAS Seminar :The Role of Life Science in Drug Discovery
          Spring, 全学共通科目
        • From Apr. 2020, To Mar. 2021
          Advanced Course in Studies on Signal Transduction
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Biological Chemistry V (Cell Biology)
          Fall, 薬学部
        • From Apr. 2020, To Mar. 2021
          Biological Chemistry 5 (Cell Biology)
          Fall, 薬学部
        • From Apr. 2021, To Mar. 2022
          ILAS Seminar : Mechanism of cancer - Basic research using Drosophila genetics
          Spring, 全学共通科目
        • From Apr. 2021, To Mar. 2022
          Advanced Course in Studies on Signal Transduction
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Introduction to Modern Life Sciences for Drug Discovery
          Spring, 薬学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Experiments in Systemic Life Sciences
          Spring, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Advanced Experiments in Systemic Life Sciences
          Fall, 生命科学研究科
        • From Apr. 2021, To Mar. 2022
          Biological Chemistry V (Cell Biology)
          Fall, 薬学部
        • From Apr. 2021, To Mar. 2022
          Biological Chemistry 5 (Cell Biology)
          Fall, 薬学部
        • From Oct. 2019, To Mar. 2022
          Pharmaceutical Laboratory IV : Biochemistry and Microbiology
          Fall, 薬学部
        • From Oct. 2019, To Mar. 2022
          Pharmaceutical Laboratory 4 : Biochemistry and Microbiology
          Fall, 薬学部
        • From Oct. 2019, To Mar. 2020
          Advanced Experiments in Systemic Life Sciences
          Fall, 生命科学研究科
        • From Oct. 2019, To Mar. 2020
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Oct. 2019, To Mar. 2020
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Oct. 2019, To Mar. 2020
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Oct. 2019, To Mar. 2020
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Experiments in Systemic Life Sciences
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Advanced Experiments in Systemic Life Sciences
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Spring, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Fall, 生命科学研究科
        • From Apr. 2020, To Mar. 2021
          Experimental Course and Seminar
          Spring, 生命科学研究科
        list
          Last Updated :2024/04/02

          Administration

          Faculty management (title, position)

          • From 01 Apr. 2023
            よろず相談窓口委員会 (ハラスメント相談窓口委員会)
          list
            Last Updated :2024/04/02

            Academic, Social Contribution

            Committee Memberships

            • From Sep. 2023, To Present
              第4回細胞競合国際シンポジウム・事務局
            • From Sep. 2021, To Present
              事務局, 学術変革領域 (A) 多細胞生命自律性
            • From 2020, To Present
              委員, 日本薬学会関西支部

            Social Contribution

            • 岡山県立津山高等学校2年生への模擬授業(「遺伝学的な考え方に触れてみよう」
              Lecturer
              From 01 Aug. 2023, To 01 Aug. 2023
            • 京都大学研修(岡山県立津山高等学校)
              Guest, Lecturer
              京都大学研修(岡山県立津山高等学校), From 02 Aug. 2022
            • 岡山県立操山中学校3年生への教育指導
              Lecturer, Consultant
              From Nov. 2014
            • 慶應義塾大学医学部オープンキャンパス
              Official expert, Performer, Contributor
              From Nov. 2018
            • 慶應義塾大学医学部オープンキャンパス
              Official expert, Performer, Contributor
              From Nov. 2017
            • JST グローバルサイエンスキャンパスプログラム(招待講演)
              Lecturer
              From 04 May 2016
            • JST グローバルサイエンスキャンパスプログラム(1年間の研究・教育指導、ヒアリング参加)
              From Oct. 2014, To Sep. 2015

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