Basic Information

Faculty

• 薬学部

Professional Memberships

• THE PHARMACEUTICAL SOCIETY OF JAPAN
• THE JAPANESE SOCIETY OF PHARMACOGNOSY
• THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN
• THE CHEMICAL SOCIETY OF JAPAN

Academic Degree

• 修士（理学）(東京大学)
• 博士（理学）(東京大学)

Research History

• From May 2018, To Present

  京都大学学際融合教育研究推進センター生理化学研究ユニット 特任講師(兼)
• From Apr. 2018, To Present

  京都大学大学院薬学研究科創発医薬科学専攻助教
• From Oct. 2015, To Apr. 2018

  Hokkaido University, Faculty of Pharmaceutical Sciences, 講師
• From Apr. 2015, To Sep. 2015

  ETH Zürich, Postdoctoral Fellow
• From Oct. 2011, To Mar. 2015

  The University of Tokyo, 薬学研究科(研究院), 助教
• From Apr. 2011, To Oct. 2011

  The University of Tokyo, Graduate School of Pharmaceutical Sciences, 博士研究員

ID,URL

• J-Global ID

  201501003312791663

• Researcher number

  70625201

researchmap URL

• https://researchmap.jp/takefumikuranaga

Research

Research Interests

• 生合成
• 有機合成化学
• 全合成
• ケミカルバイオロジー
• ペプチド
• 天然物化学

Research Areas

• Life sciences, Pharmaceuticals - chemistry and drug development

Papers

• Structural Elucidation using Highly Sensitive Labeling Reagents and Total Synthesis of Amoxetamide A, a New Anoikis Inducer

  Tensei Tokuda; Takefumi Kuranaga; Mayuri Minote; Taiki Suo; Hiroaki Ikeda; Chengqian Pan; Hideaki Kakeya

  Chemistry – A European Journal, 28 Feb. 2025, Peer-reviewed, Corresponding author

  
• Twisted Amide‐Mediated Synthesis and Rapid Structure‐Activity Relationship Study of Medium‐Sized Cyclic Peptides

  Takefumi Kuranaga; Ai Koyama; Junta Asano; Takumi Matsumoto; Hideaki Kakeya

  Chemistry – A European Journal, 25 Feb. 2025, Peer-reviewed, Lead author, Corresponding author

  
• Simultaneous Analysis of Imidazole Dipeptides, Constituent Amino Acids, and Taurine in Meats Using the Highly Sensitive Labeling Reagent l-FDVDA and PBr Column.

  Makoto Ozaki; Tomomi Nakade; Mayu Sekiguchi; Motoshi Shimotsuma; Tsunehisa Hirose; Takahiro Kawase; Ai Tsuji; Takefumi Kuranaga; Hideaki Kakeya; Shozo Tomonaga

  Journal of agricultural and food chemistry, 26 Nov. 2024, Peer-reviewed

  
• Twisted Amide‐Mediated Peptide Synthesis

  Ai Koyama; Takefumi Kuranaga; Taiki Suo; Ryota Morimoto; Takumi Matsumoto; Hideaki Kakeya

  Chemistry – A European Journal, 27 Sep. 2024, Peer-reviewed, Corresponding author

  
• Simultaneous analysis of DL-Amino acids in foods and beverages using a highly sensitive chiral resolution labeling reagent

  Makoto Ozaki; Tomomi Nakade; Motoshi Shimotsuma; Akari Ikeda; Takefumi Kuranaga; Hideaki Kakeya; Tsunehisa Hirose

  Journal of Chromatography B, Aug. 2024, Peer-reviewed

  
• Simultaneous separation and identification of all structural isomers and enantiomers of aminobutyric acid using a highly sensitive chiral resolution labeling reagent

  Makoto Ozaki; Motoshi Shimotsuma; Takefumi Kuranaga; Hideaki Kakeya; Tsunehisa Hirose

  Analytical Methods, 2023, Peer-reviewed

  
• Amoxetamide A, a new anoikis inducer, produced by combined-culture of Amycolatopsis sp. and Tsukamurella pulmonis

  Chengqian Pan; Hiroaki Ikeda; Mayuri Minote; Tensei Tokuda; Takefumi Kuranaga; Tohru Taniguchi; Naoya Shinzato; Hiroyasu Onaka; Hideaki Kakeya

  The Journal of Antibiotics, 2024, Peer-reviewed

  
• Separation and Identification of Isoleucine Enantiomers and Diastereomers Using an Original Chiral Resolution Labeling Reagent

  Makoto Ozaki; Motoshi Shimotsuma; Takefumi Kuranaga; Hideaki Kakeya; Tsunehisa Hirose

  Chemical and Pharmaceutical Bulletin, 01 Nov. 2023, Peer-reviewed

  
• Total syntheses of surugamides and thioamycolamides toward understanding their biosynthesis

  Takefumi Kuranaga

  Journal of Natural Medicines, 08 Nov. 2022, Peer-reviewed, Invited, Lead author, Last author, Corresponding author

  
• Separation of amyloid β fragment peptides with racemised and isomerised aspartic acid residues using an original chiral resolution labeling reagent

  Makoto Ozaki; Motoshi Shimotsuma; Takefumi Kuranaga; Hideaki Kakeya; Tsunehisa Hirose

  The Analyst, 2023, Peer-reviewed

  
• Solid-phase total synthesis and structural confirmation of antimicrobial longicatenamide A

  Takumi Matsumoto; Takefumi Kuranaga; Yuto Taniguchi; Weicheng Wang; Hideaki Kakeya

  Beilstein Journal of Organic Chemistry, 18 Nov. 2022, Peer-reviewed, Corresponding author

  Access this paper :

  
• P-60 Convergent Synthesis of Simplified Polycyclic Ethers and Studies on their Interaction with Membrane Proteins

  Sasaki Masato; Kuranaga Takefumi; Murata Misako; Tachibana Kazuo

  Symposium on the Chemistry of Natural Products, symposium papers, 15 Sep. 2006

  
• Identification and Total Synthesis of an Unstable Anticancer Macrolide Presaccharothriolide Z Produced by Saccharothrix sp. A1506

  Takefumi Kuranaga; Miho Tamura; Hiroaki Ikeda; Sakahiro Terada; Yusuke Nakagawa; Hideaki Kakeya

  Organic Letters, 17 Sep. 2021, Peer-reviewed, Lead author, Corresponding author

  
• Amycolapeptins A and B, Cyclic Nonadepsipeptides Produced by Combined-culture of Amycolatopsis sp. and Tsukamurella pulmonis

  Chengqian Pan; Takefumi Kuranaga; Xun Cao; Takehiro Suzuki; Naoshi Dohmae; Naoya Shinzato; Hiroyasu Onaka; Hideaki Kakeya

  The Journal of Organic Chemistry, 15 Jan. 2021, Peer-reviewed

  
• Application of the highly sensitive labeling reagent to the structural confirmation of readily isomerizable peptides

  Chengqian Pan; Takefumi Kuranaga; Hideaki Kakeya

  Journal of Natural Medicines, 02 Jan. 2021, Peer-reviewed, Corresponding author

  
• Longicatenamides A–D, Two Diastereomeric Pairs of Cyclic Hexapeptides Produced by Combined-culture of Streptomyces sp. KUSC_F05 and Tsukamurella pulmonis TP-B0596

  Yulu Jiang; Takumi Matsumoto; Takefumi Kuranaga; Shan Lu; Weicheng Wang; Hiroyasu Onaka; Hideaki Kakeya

  The Journal of Antibiotics, Jan. 2021, Peer-reviewed

  
• Highly sensitive determination of amino acids by LC-MS under neutral conditions

  Ryota Morimoto; Takumi Matsumoto; Mayuri Minote; Masayuki Yanagisawa; Ryotaro Yamada; Takefumi Kuranaga; Hideaki Kakeya

  Chem. Pharm. Bull., Jan. 2021, Peer-reviewed, Corresponding author

  
• Total Synthesis and Structural Revision of Kasumigamide, and Identification of a New Analogue

  Takefumi Kuranaga; Kenichi Matsuda; Masachika Takaoka; Chisato Tachikawa; Ayae Sano; Kosei Itoh; Ayumu Enomoto; Kei Fujita; Ikuro Abe; Toshiyuki Wakimoto

  ChemBioChem, Dec. 2020, Peer-reviewed, Lead author, Corresponding author

  
• Total synthesis of thioamycolamide A via a biomimetic route

  Chengqian Pan; Takefumi Kuranaga; Hideaki Kakeya

  Organic & Biomolecular Chemistry, Oct. 2020, Peer-reviewed, Corresponding author

  
• Highly Sensitive Labeling Reagents for Scarce Natural Products

  Takefumi Kuranaga; Mayuri Minote; Ryota Morimoto; Chengqian Pan; Haruka Ogawa; Hideaki Kakeya

  ACS Chemical Biology, 31 Aug. 2020, Peer-reviewed, Lead author, Corresponding author

  
• Thioamycolamides A–E, Sulfur-Containing Cycliclipopeptides Produced by the Rare Actinomycete Amycolatopsis sp.

  Chengqian Pan; Takefumi Kuranaga; Chao Liu; Shan Lu; Naoya Shinzato; Hideaki Kakeya

  Organic Letters, 17 Apr. 2020, Peer-reviewed

  
• Precious Microorganisms as Productive Resources: Marine-Derived Microorganisms and Combined-Culture

  Hideaki Kakeya; Takefumi Kuranaga

  Comprehensive Natural Products III, 2020, Peer-reviewed, Invited

  
• 化学合成を基盤とする稀少天然物化学研究 稀少天然物に着想を得た高感度ラベル化剤の開発

  倉永健史

  化学と工業, 2020

  
• Introduction of D-Amino Acids in Minimalistic Peptide Substrates by an S-Adenosyl-L-Methionine Radical Epimerase

  Anna L. Vagstad; Takefumi Kuranaga; Salome Püntener; Vijaya R. Pattabiraman; Jeffrey W. Bode; Jörn Piel

  Angewandte Chemie International Edition, 18 Feb. 2019, Peer-reviewed

  
• ペニシリン結合タンパク質によるペプチド環化

  松田研一; 倉永健史; 脇本敏幸

  ファルマシア, 2019, Peer-reviewed

  
• A new cyclase family catalyzing head-to-tail macrolactamization of non-ribosomal peptides

  Kenichi Matsuda; Takefumi Kuranaga; Toshiyuki Wakimoto

  J. Synth. Org. Chem. Jpn., 2019, Peer-reviewed

  
• The Revised Structure of the Cyclic Octapeptide Surugamide A

  Kenichi Matsuda; Takefumi Kuranaga; Ayae Sano; Akihiro Ninomiya; Kentaro Takada; Toshiyuki Wakimoto

  Chem. Pharm. Bull., 2019, Peer-reviewed, Corresponding author

  
• Scrobiculosides A and B from the Deep-Sea Sponge Pachastrella scrobiculosa

  Takahiro Jomori; Shuji Shiroyama; Yuji Ise; Hisanori Kohtsuka; Kenichi Matsuda; Takefumi Kuranaga; Toshiyuki Wakimoto

  J. Nat. Med., 2019, Peer-reviewed

  
• SurE is a trans-acting thioesterase cyclizing two distinct non-ribosomal peptides

  Kenichi Matsuda; Masakazu Kobayashi; Takefumi Kuranaga; Kentaro Takada; Shigeki Matsunaga; Haruo Ikeda; Toshiyuki Wakimoto

  Org. Biomol. Chem., 2019, Peer-reviewed

  
• Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes.

  Yuka Unno; Hirona Yamamoto; Shuto Takatsuki; Yoshinori Sato; Takefumi Kuranaga; Kazunaga Yazawa; Yasuo Ono; Toshiyuki Wakimoto

  Biochimica et biophysica acta. Molecular and cell biology of lipids, Jul. 2018, Peer-reviewed

  
• Total Synthesis of the Non-Ribosomal Peptide Surugamide B and Identification of a New Offloading Cyclase Family

  Takefumi Kuranaga; Kenichi Matsuda; Ayae Sano; Masakazu Kobayashi; Akihiro Ninomiya; Kentaro Takada; Shigeki Matsunaga; Toshiyuki Wakimoto

  Angew. Chem. Int. Ed., 2018, Peer-reviewed, Lead author, Corresponding author

  
• Diastereoselective total synthesis and structural confirmation of surugamide F

  Takefumi Kuranaga; Atsuki Fukuba; Akihiro Ninomiya; Kentaro Takada; Shigeki Matsunaga; Toshiyuki Wakimoto

  Chemical and Pharmaceutical Bulletin, 2018, Peer-reviewed, Lead author, Corresponding author

  
• Total Synthesis of Theonellapeptolide Id

  Takefumi Kuranaga; Ayumu Enomoto; Hui Tan; Kazuto Fujita; Toshiyuki Wakirnoto

  ORGANIC LETTERS, Mar. 2017, Peer-reviewed, Lead author

  
• Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase

  Daniel Ken Inaoka; Maiko Lida; Satoshi Hashimoto; Toshiyuki Tabuchi; Takefumi Kuranaga; Emmanuel Oluwadare Balogun; Teruki Honma; Akiko Tanaka; Shigeharu Harada; Takeshi Nara; Kiyoshi Kita; Masayuki Inoue

  BIOORGANIC & MEDICINAL CHEMISTRY, Feb. 2017, Peer-reviewed

  
• Corrigendum to: Biosynthetic Gene Cluster for Surugamide A Encompasses an Unrelated Decapeptide, Surugamide F (ChemBioChem, (2016), 17, 18, (1709-1712), 10.1002/cbic.201600350)

  Ninomiya A; Katsuyama Y; Kuranaga T; Miyazaki M; Nogi Y; Okada S; Wakimoto T; Ohnishi Y; Matsunaga S; Takada K

  ChemBioChem, 2017, Peer-reviewed

  
• セリンライゲーションを鍵としたteixobactinの全合成

  倉永健史

  ファルマシア, 2017, Peer-reviewed, Lead author, Corresponding author

  
• The Open Form Inducer Approach for Structure-Based Drug Design

  Daniel Ken Inaoka; Maiko Iida; Toshiyuki Tabuchi; Teruki Honma; Nayoung Lee; Satoshi Hashimoto; Shigeru Matsuoka; Takefumi Kuranaga; Kazuhito Sato; Tomoo Shiba; Kimitoshi Sakamoto; Emmanuel Oluwadare Balogun; Shigeo Suzuki; Takeshi Nara; Josmar Rodrigues da Rocha; Carlos Alberto Montanari; Akiko Tanaka; Masayuki Inoue; Kiyoshi Kita; Shigeharu Harada

  PLOS ONE, Nov. 2016, Peer-reviewed

  
• Biosynthetic Gene Cluster for SurugamideA Encompasses an Unrelated Decapeptide, SurugamideF

  Akihiro Ninomiya; Yohei Katsuyama; Takefumi Kuranaga; Masayuki Miyazaki; Yuichi Nogi; Shigeru Okada; Toshiyuki Wakimoto; Yasuo Ohnishi; Shigeki Matsunaga; Kentaro Takada

  CHEMBIOCHEM, Sep. 2016, Peer-reviewed

  
• The total synthesis and functional evaluation of fourteen stereoisomers of yaku'amide B. The importance of stereochemistry for hydrophobicity and cytotoxicity

  Hiroyuki Mutoh; Yusuke Sesoko; Takefumi Kuranaga; Hiroaki Itoh; Masayuki Inoue

  ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, Peer-reviewed

  
• Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the mu-Opioid Receptor

  Junya Okude; Takumi Ueda; Yutaka Kofuku; Motohiko Sato; Naoyuki Nobuyama; Keita Kondo; Yutaro Shiraishi; Takuya Mizumura; Kento Onishi; Mei Natsume; Masahiro Maeda; Hideki Tsujishita; Takefumi Kuranaga; Masayuki Inoue; Ichio Shimada

  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Dec. 2015, Peer-reviewed

  
• Elucidation and Total Synthesis of the Correct Structures of Tridecapeptides Yaku'amides A and B. Synthesis-Driven Stereochemical Reassignment of Four Amino Acid Residues

  Takefumi Kuranaga; Hiroyuki Mutoh; Yusuke Sesoko; Tomomi Goto; Shigeki Matsunaga; Masayuki Inoue

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Jul. 2015, Peer-reviewed, Lead author

  
• Solid-Phase Total Synthesis of Bogorol A: Stereocontrolled Construction of Thermodynamically Unfavored (E)-2-Amino-2-butenamide

  Tomoya Yamashita; Takefumi Kuranaga; Masayuki Inoue

  ORGANIC LETTERS, May 2015, Peer-reviewed

  
• Rational Design, Synthesis, and Biological Evaluation of Lactam-Bridged Gramicidin A Analogues: Discovery of a Low-Hemolytic Antibacterial Peptide

  Ji Mao; Takefumi Kuranaga; Hiroshi Hamamoto; Kazuhisa Sekimizu; Masayuki Inoue

  CHEMMEDCHEM, Mar. 2015, Peer-reviewed

  
• Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane

  Hiroshi Hamamoto; Makoto Urai; Kenichi Ishii; Jyunichiro Yasukawa; Atmika Paudel; Motoki Murai; Takuya Kaji; Takefumi Kuranaga; Kenji Hamase; Takashi Katsu; Jie Su; Tatsuo Adachi; Ryuji Uchida; Hiroshi Tomoda; Maki Yamada; Manabu Souma; Hiroki Kurihara; Masayuki Inoue; Kazuhisa Sekimizu

  NATURE CHEMICAL BIOLOGY, Feb. 2015, Peer-reviewed

  
• Total Synthesis and Biological Evaluation of the Antibiotic Lysocin E and Its Enantiomeric, Epimeric, and N-Demethylated Analogues

  Motoki Murai; Takuya Kaji; Takefumi Kuranaga; Hiroshi Hamamoto; Kazuhisa Sekimizu; Masayuki Inoue

  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Jan. 2015, Peer-reviewed

  
• Total syntheses of nobilamides B and D: application of traceless Staudinger ligation

  Tomoya Yamashita; Hiroaki Matoba; Takefumi Kuranaga; Masayuki Inoue

  TETRAHEDRON, Oct. 2014, Peer-reviewed

  
• SYNTHESIS AND CYCLIZATION OF A PROPOSED BIOSYNTHETIC EPDXY INTERMEDIATE OF A MRINE MONOCYCLIC ETHER AMIDE, BREVISAMIDE

  Tomohiro Shirai; Yuki Takimoto; Takefumi Kuranaga; Kazuo Tachibana; Masayuki Satake; Daniel G. Baden; Jeffrey L. C. Wright

  HETEROCYCLES, Jan. 2014, Peer-reviewed

  
• Control of the cytotoxicity of dansylated polytheonamide mimic, an artificial peptide ion channel, by modification of the N-terminal structure

  Hiroaki Itoh; Shoko Matsutaka; Takefumi Kuranaga; Masayuki Inoue

  TETRAHEDRON LETTERS, Jan. 2014, Peer-reviewed

  
• Cu-mediated enamide formation in the total synthesis of complex peptide natural products

  Takefumi Kuranaga; Yusuke Sesoko; Masayuki Inoue

  NATURAL PRODUCT REPORTS, 2014, Peer-reviewed, Lead author

  
• Total Synthesis and Complete Structural Assignment of Yaku'amide A

  Takefumi Kuranaga; Yusuke Sesoko; Komei Sakata; Naoya Maeda; Atsushi Hayata; Masayuki Inoue

  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Apr. 2013, Peer-reviewed, Lead author

  
• Ophiobolin O and 6-Epi-ophiobolin O, Two New Cytotoxic Sesterterpenes from the Marine Derived Fungus Aspergillus sp.

  Dahai Zhang; Seketsu Fukuzawa; Masayuki Satake; Xianguo Li; Takafumi Kuranaga; Ai Niitsu; Kentaro Yoshizawa; Kazuo Tachibana

  NATURAL PRODUCT COMMUNICATIONS, Nov. 2012, Peer-reviewed

  
• Total Synthesis of (-)-Brevisin: A Concise Synthesis of a New Marine Polycyclic Ether

  Takefumi Kuranaga; Naohito Ohtani; Ryosuke Tsutsumi; Daniel G. Baden; Jeffrey L. C. Wright; Masayuki Satake; Kazuo Tachibana

  ORGANIC LETTERS, Feb. 2011, Peer-reviewed, Lead author

  
• Chemoselective deprotection of silyl ethers by DIBALH

  Takefumi Kuranaga; Shuji Ishihara; Naohito Ohtani; Masayuki Satake; Kazuo Tachibana

  TETRAHEDRON LETTERS, Dec. 2010, Peer-reviewed, Lead author

  
• A Concise Total Synthesis of a New Polycyclic Ether, Brevisin

  Kuranaga Takefumi; Ohtani Naohito; Tsutsumi Ryosuke; Ishihara Shuji; Satake Masayuki; Wright Jeffrey L.C.; Tachibana Kazuo

  Symposium on the Chemistry of Natural Products, symposium papers, 01 Sep. 2010

  
• Synthesis of the BC/DE ring model of brevisin for confirmation of the structure around the acyclic junction

  Takefumi Kuranaga; Masayuki Satake; Daniel G. Baden; Jeffrey L. C. Wright; Kazuo Tachibana

  TETRAHEDRON LETTERS, Sep. 2010, Peer-reviewed, Lead author

  
• An improved synthesis of (-)-brevisamide, a marine monocyclic ether amide of dinoflagellate origin

  Ryosuke Tsutsumi; Takefumi Kuranaga; Jeffrey L. C. Wright; Daniel G. Baden; Emiko Ito; Masayuki Satake; Kazuo Tachibana

  TETRAHEDRON, Aug. 2010, Peer-reviewed

  
• Synthesis of a proposed biosynthetic intermediate of a marine cyclic ether brevisamide for study on biosynthesis of marine ladder-frame polyethers

  Tomohiro Shirai; Takefumi Kuranaga; Jeffrey L. C. Wright; Daniel G. Baden; Masayuki Satake; Kazuo Tachibana

  TETRAHEDRON LETTERS, Mar. 2010, Peer-reviewed

  
• SYNTHESIS OF THE ABC RING FRAGMENT OF BREVISIN, A NEW DINOFLAGELLATE POLYCYCLIC ETHER

  Naohito Ohtani; Ryosuke Tsutsumi; Takefumi Kuranaga; Tomohiro Shirai; Jeffrey L. C. Wright; Daniel G. Baden; Masayuki Satake; Kazuo Tachibanaa

  HETEROCYCLES, Mar. 2010, Peer-reviewed

  
• Synthesis of brevisamide and its plausible biosynthetic precursors for elucidation of biosynthetic mechanism of marine ladder-shaped polyethers

  Kuranaga Takefumi; Shirai Tomohiro; Tsutsumi Ryosuke; Ohtani Naohito; Wright Jeffrey L.C.; Satake Masayuki; Tachibana Kazuo

  Symposium on the Chemistry of Natural Products, symposium papers, 01 Sep. 2009

  
• Total Synthesis and Structural Confirmation of Brevisamide, a New Marine Cyclic Ether Alkaloid from the Dinoflagellate Karenia brevis

  Takefumi Kuranaga; Tomohiro Shirai; Daniel G. Baden; Jeffrey L. C. Wright; Masayuki Satake; Kazuo Tachibana

  ORGANIC LETTERS, Jan. 2009, Peer-reviewed, Lead author

  
• Separation and identification of the DL-forms of short-chain peptides using a new chiral resolution labeling reagent

  Makoto Ozaki; Tomomi Kuwayama; Tsunehisa Hirose; Motoshi Shimotsuma; Akira Hashimoto; Takefumi Kuranaga; Hideaki Kakeya

  Analytical and Bioanalytical Chemistry, Jun. 2022, Peer-reviewed

  
• Development and application of highly sensitive labeling reagents for amino acids

  Takefumi Kuranaga; Hideaki Kakeya

  Methods in Enzymol., Mar. 2022, Peer-reviewed, Lead author

  

Misc.

• Synthetic study on the natural prodrug anticancer compound, saccharothriolide B

  田村美帆; 中川雄介; 倉永健史; 掛谷秀昭

  日本薬学会年会要旨集(CD-ROM), 2020

  
• フラン脂肪酸の合成と抗炎症作用解析

  高槻修人; 海野雄加; 戸田直希; 倉永健史; 斧康雄; 脇本敏幸

  食品薬学シンポジウム講演要旨集, Oct. 2017

  
• クリルオイル中の脂肪細胞分化促進成分の探索

  山本宙奈; 高槻修人; 海野雄加; 倉永健史; 斧康雄; 脇本敏幸

  第64回北海道薬学大会, May 2017

  
• μ‐オピオイド受容体のシグナル選択性制御機構の解明

  奥出順也; 上田卓見; 上田卓見; 上田卓見; 幸福裕; 佐藤元彦; 延山尚幸; 近藤啓太; 白石勇太郎; 水村拓也; 大西健人; 夏目芽依; 前田正洋; 辻下英樹; 倉永健史; 井上将行; 嶋田一夫

  Abstracts. Annual Meeting of the NMR Society of Japan, 16 Nov. 2016

  
• フラン脂肪酸の定量分析と生物活性評価

  高槻修人; 山本宙奈; 江上蓉子; 倉永健史; 脇本敏幸; 海野雄加; 斧康雄

  第63回北海道薬学大会, May 2016

  
• δオピオイド受容体(δOR)の活性制御機構の解明

  佐藤元彦; 奥出順也; 延山尚幸; 上田卓見; 上田卓見; 幸福裕; 倉永健史; 井上将行; 嶋田一夫

  日本薬学会年会要旨集(CD-ROM), Mar. 2016

  
• Total synthesis and structure-function relationship study of kaikosins

  Kaji Takuya; Murai Motoki; Kuranaga Takefumi; Hamamoto Hiroshi; Sekimizu Kazuhisa; Inoue Masayuki

  Symposium on the Chemistry of Natural Products, symposium papers, 2014

  

Books and Other Publications

• 生薬・薬用植物研究の最新動向 化学合成を駆使した稀少天然物化学研究

  倉永健史, 化学合成を駆使した稀少天然物化学研究

  シーエムシー出版, 2017, Not refereed

  

Industrial Property Rights

• 特願2023-147238, 新規アミド化反応

  掛谷秀昭; 倉永健 史; 小山愛

  
• 特願2019-081766, 新規フルオロジニトロフェニル化合物及びその用途

  小川はるか; 倉永健史; 掛谷秀昭

  
• 特願2018-89287, ペプチド類の大環状化酵素

  脇本敏幸; 倉永健史; 松田研一

  
• 特願2013-098834, 固相レジンを用いた環状ペプチド化合物の製造方法

  関水和久; 井上将行; 倉永健史

  

External funds: Kakenhi

• Development and applications of biomimetic peptide synthesis

  Grant-in-Aid for Early-Career Scientists

  Basic Section 38040:Bioorganic chemistry-related

  Kyoto University

  Takefumi Kuranaga

  From 01 Apr. 2018, To 31 Mar. 2020, Project Closed

  ペプチド;生合成;有機合成;全合成;天然物化学

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K14396/
• Bioactive secondary metabolites produced by sponge symbiont Entotheonella

  Grant-in-Aid for Scientific Research (B)

  Hokkaido University

  Toshiyuki WAKIMOTO

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  海綿動物;生合成遺伝子;生物活性物質;生合成;共生微生物;海綿共生微生物;二次代謝産物;ペプチド;海綿;Entotheonella

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H03112/
• Development and Application of Convergent Strategies for Unified Total Syntheses of Architecturally Complex Natural Products

  Grant-in-Aid for Scientific Research (A)

  The University of Tokyo

  Masayuki Inoue

  From 01 Apr. 2014, To 31 Mar. 2017, Project Closed

  合成化学;全合成;生物活性分子の設計;生理活性;収束的合成;ラジカル反応

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26253003/
• Synthetic and structure-activity relationship study on a new anticancer agent, yaku'amide A

  Grant-in-Aid for Young Scientists (B)

  The University of Tokyo

  Takefumi KURANAGA

  From 01 Apr. 2012, To 31 Mar. 2014, Project Closed

  ケミカルバイオロジー;ペプチド;全合成;ヤクアミド

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24790005/
• 縮合剤を用いないアミド化反応の開発とそのペプチド合成への応用

  Grant-in-Aid for Scientific Research (C)

  Basic Section 33020:Synthetic organic chemistry-related

  Kyoto University

  倉永 健史

  From 01 Apr. 2022, To 31 Mar. 2025, Granted

  有機合成化学;ペプチド;天然物化学;グリーンケミストリー;サステナブルケミストリー;生合成

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K05112/
• ねじれ型アミドを介する低コストかつサステナブルなアミド化反応の開発と応用

  Grant-in-Aid for Scientific Research (C)

  Basic Section 33020:Synthetic organic chemistry-related

  Kyoto University

  倉永 健史

  From 01 Apr. 2025, To 31 Mar. 2028, Adopted

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25K08639/

Education

Teaching subject(s)

• From 01 Apr. 2025, To 31 Mar. 2026

  Seminar on Critical Reading of Scientific Papers B

  8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2025, To 31 Mar. 2026

  Medicinal Frontier Science Research C

  8408, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2025, To 31 Mar. 2026

  Medicinal Frontier Science Research B

  8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2025, To 31 Mar. 2026

  Medicinal Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2025, To 31 Mar. 2026

  Outline of Physiological Chemistry

  X101, Fall, Graduate School of Agriculture, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Research Proposal Writing Practice B

  8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Research Proposal Writing Practice A

  8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory Coaching Practice B

  8302, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory Coaching Practice A

  8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Organic Chemistry Seminar

  C018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Organic Chemistry Exercise 2

  A018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar on Critical Reading of Scientific Papers B

  8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Pharmaceutical Laboratory II : Organic Chemistry

  C902, Spring, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2024, To 31 Mar. 2025

  Medicinal Frontier Science Research C

  8408, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Medicinal Frontier Science Research B

  8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Medicinal Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Research Proposal Writing Practice B

  8403, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Research Proposal Writing Practice A

  8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory Coaching Practice B

  8302, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory Coaching Practice A

  8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory II : Organic Chemistry

  C902, Spring, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2023, To 31 Mar. 2024

  Medicinal Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Skill Development for Lead Discovery

  5102, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Medicinal Frontier Science Research B

  8407, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Pharmaceutical Laboratory 2 : Organic Chemistry

  A902, Spring, Faculty of Pharmaceutical Sciences, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar on Critical Reading of Scientific Papers B

  8405, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Organic Chemistry Exercise 2

  A018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Organic Chemistry Seminar

  C018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Fundamental Chemical Experiments

  N308, Fall, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Organic Chemistry Seminar

  C018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Medical Frontier Science Research A

  8406, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Skill Development for Lead Discovery

  5102, Year-long, Graduate School of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Research Proposal Writing Practice A

  8402, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory Coaching Practice A

  8301, Year-long, Graduate School of Pharmaceutical Sciences, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Organic Chemistry Exercise 2

  A018, Spring, Faculty of Pharmaceutical Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory 2 : Organic Chemistry

  A902, Spring, Faculty of Pharmaceutical Sciences, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Pharmaceutical Laboratory II : Organic Chemistry

  C902, Spring, Faculty of Pharmaceutical Sciences, 3
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar on Critical Reading of Scientific Papers A

  8404, Year-long, Graduate School of Pharmaceutical Sciences, 2
• From Apr. 2019, To Mar. 2020

  Organic Chemistry Exercise 2

  Fall, 薬学部
• From Apr. 2019, To Mar. 2020

  Organic Chemistry Seminar

  Fall, 薬学部
• From Apr. 2019, To Mar. 2020

  Skill Development for Lead Discovery

  Year-long, 薬学研究科
• From Apr. 2019, To Mar. 2020

  Pharmaceutical Laboratory 2 : Organic Chemistry

  Spring, 薬学部
• From Apr. 2020, To Mar. 2021

  Organic Chemistry Exercise 2

  Spring, 薬学部
• From Apr. 2020, To Mar. 2021

  Organic Chemistry Seminar

  Spring, 薬学部
• From Apr. 2020, To Mar. 2021

  Skill Development for Lead Discovery

  Year-long, 薬学研究科
• From Apr. 2020, To Mar. 2021

  Pharmaceutical Laboratory II : Organic Chemistry

  Spring, 薬学部
• From Apr. 2020, To Mar. 2021

  Pharmaceutical Laboratory 2 : Organic Chemistry

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Organic Chemistry Exercise 2

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Organic Chemistry Seminar

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Skill Development for Lead Discovery

  Year-long, 薬学研究科
• From Apr. 2021, To Mar. 2022

  Pharmaceutical Laboratory II : Organic Chemistry

  Spring, 薬学部
• From Apr. 2021, To Mar. 2022

  Pharmaceutical Laboratory 2 : Organic Chemistry

  Spring, 薬学部

Administration

Faculty management (title, position)

• From 01 Apr. 2022, To 31 Mar. 2025

  情報システム委員会　委員
• From 01 Apr. 2019, To 31 Mar. 2023

  ＮＭＲ運営管理委員会 委員

Academic, Social Contribution

Committee Memberships

• From Apr. 2017, To Jun. 2021

  天然物化学談話会世話人
• From Apr. 2017, To Mar. 2018

  日本生薬学会北海道支部役員
• From Apr. 2012, To Mar. 2014

  有機合成化学協会誌編集委員