Basic Information

Affiliated programs (koza)

• Graduate School of Biostudies, 高次生命科学専攻 生体動態制御学, 教授
• Graduate School of Medicine, 医学専攻 分子ウイルス学, 教授
• Graduate School of Medicine, 医科学専攻 分子ウイルス学, 教授

Professional Memberships

• To Present

  日本分子生物学会
• To Present

  Japan Society of Gene and Cell Therapy
• To Present

  RNA Society of Japan
• To Present

  日本獣医学会
• To Present

  日本ウイルス学会
• Society of Evolutionary Studies
• Japanese Society of Veterinary Science
• Japanese Society for Virology

Academic Degree

• 博士（獣医学）(東京大学)

Research History

• From Feb. 2011, To Present

  Institute for Life and Medical Sciences (LiMe), Kyoto University, Professor
• From Dec. 2000, To Jan. 2011

  Osaka University Research Institute for Microbial Diseases, Associated Professor
• From Apr. 1999, To Nov. 2000

  Osaka University Research Institute for Microbial Diseases, Assistant Professor
• From 1998, To 1999

  北海道大学免疫科学研究所 助手
• From 1997, To 1998

  アメリカ白血病協会 特別研究員(ボストン・タフツ大学)
• From 1995, To 1997

  日本学術振興会 海外特別研究員(ボストン・タフツ大学)
• From 1994, To 1995

  日本学術振興会 特別研究員(東京大学)

Language of Instruction

• English

ID,URL

• ORCID ID

  0000-0003-0405-7103

• J-Global ID

  200901078472628957

researchmap URL

• https://researchmap.jp/kt05070331

Research

Research Topics, Overview of the research

• Research Topics

  Studies on RNA viruses (bornavirus and influenza virus). Analysis of endogenous viruses. Development of Virus vectors.

• Overview of the research

  The researches carried out in this group are focused on RNA viruses, especially negative strand RNA viruses replicating in the cell nucleus, such as bornavirus and influenza virus. All our projects aim to understand the fundamental mechanisms of the replication and pathogenesis of the viruses. The understanding the biological significance of the endogenous element of bornavirus nucleoprotein (EBLN) in mammalian genomes is one of the main focuses of bornavirus researches.

Research Areas

• Life sciences, Virology
• Life sciences, Veterinary medicine

Papers

• Interferon and TLR genes, but not endogenous bornavirus-like elements, limit BoDV1 replication after intracerebral infection.

  Rie Koide; Takaya Abe; Taichi Harimoto; Anselmo Jiro Kamada; Yuka Saito; Matteo Guerrini; Asami Fujii; Erica Parrish; Masayuki Horie; Hiroshi Kiyonari; Kazuhiko Yamamoto; Keizo Tomonaga; Nicholas F Parrish

  PLoS pathogens, 09 May 2025

  
• Development of an RNA virus-based episomal vector with artificial aptazyme for gene silencing

  Ryo Komorizono; Shima Yoshizumi; Keizo Tomonaga

  Applied Microbiology and Biotechnology, 18 Oct. 2024

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• Distribution of lesions in psittacine birds naturally infected with parrot bornavirus in Japan

  Chinatsu FUJIWARA; Naoyuki AIHARA; Motokazu YOSHINO; Takanori SHIGA; Kan FUJINO; Ryo KOMORIZONO; Akiko MAKINO; Keizo TOMONAGA; Reiko SOGA; Junichi KAMIIE

  Journal of Veterinary Medical Science, 2024

  
• A single amino acid substitution in the Borna disease virus glycoprotein enhances the infectivity titer of vesicular stomatitis virus pseudotyped virus by altering membrane fusion activity

  Yusa Akiba; Hiromichi Matsugo; Takehiro Kanda; Modoka Sakai; Akiko Makino; Keizo Tomonaga

  22 May 2024

  
• Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells.

  Takehiro Kanda; Pauline Dianne Santos; Dirk Höper; Martin Beer; Dennis Rubbenstroth; Keizo Tomonaga

  Npj viruses, 17 Apr. 2025

  
• An Infection Model for SARS-CoV-2 Using Rat Transplanted with hiPSC-Airway Epithelial Cells.

  Masayuki Kitano; Hiroe Ohnishi; Akiko Makino; Tatsuo Miyamoto; Yasuyuki Hayashi; Keisuke Mizuno; Shinji Kaba; Yoshitaka Kawai; Tsuyoshi Kojima; Yo Kishimoto; Norio Yamamoto; Keizo Tomonaga; Koichi Omori

  Tissue engineering. Part A, 27 Jun. 2024

  
• Predicted risk of heart failure pandemic due to persistent SARS-CoV-2 infection using a three-dimensional cardiac model.

  Kozue Murata; Akiko Makino; Keizo Tomonaga; Hidetoshi Masumoto

  iScience, 19 Jan. 2024

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• Reverse genetics of parrot bornavirus 4 reveals a unique splicing of the glycoprotein gene that affects viral propagation

  Ryo Komorizono; Kan Fujino; Susanne Kessler; Solveig Runge; Takehiro Kanda; Masayuki Horie; Akiko Makino; Dennis Rubbenstroth; Keizo Tomonaga

  Journal of Virology, 31 Aug. 2023

  
• Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota).

  Jens H Kuhn; Junya Abe; Scott Adkins; Sergey V Alkhovsky; Tatjana Avšič-Županc; María A Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J Ballinger; Virendra Kumar Baranwal; Martin Beer; Nicolas Bejerman; Éric Bergeron; Nadine Biedenkopf; Carol D Blair; Kim R Blasdell; Arnaud G Blouin; Steven B Bradfute; Thomas Briese; Paul A Brown; Ursula J Buchholz; Michael J Buchmeier; Alexander Bukreyev; Felicity Burt; Carmen Büttner; Charles H Calisher; Mengji Cao; Inmaculada Casas; Kartik Chandran; Rémi N Charrel; Krishna Kumar Chaturvedi; Kar Mun Chooi; Anya Crane; Elena Dal Bó; Juan Carlos de la Torre; William M de Souza; Rik L de Swart; Humberto Debat; Nolwenn M Dheilly; Nicholas Di Paola; Francesco Di Serio; Ralf G Dietzgen; Michele Digiaro; J Felix Drexler; W Paul Duprex; Ralf Dürrwald; Andrew J Easton; Toufic Elbeaino; Koray Ergünay; Guozhong Feng; Andrew E Firth; Anthony R Fooks; Pierre B H Formenty; Juliana Freitas-Astúa; Selma Gago-Zachert; María Laura García; Adolfo García-Sastre; Aura R Garrison; Thomas R Gaskin; Wenjie Gong; Jean-Paul J Gonzalez; JoëlleGoüy de Bellocq; Anthony Griffiths; Martin H Groschup; Ines Günther; Stephan Günther; John Hammond; Yusuke Hasegawa; Kazusa Hayashi; Jussi Hepojoki; Colleen M Higgins; Seiji Hongō; Masayuki Horie; Holly R Hughes; Adam J Hume; Timothy H Hyndman; Kenichi Ikeda; Dàohóng Jiāng; Gilda B Jonson; Sandra Junglen; Boris Klempa; Jonas Klingström; Hideki Kondō; Eugene V Koonin; Mart Krupovic; Kenji Kubota; Gael Kurath; Lies Laenen; Amy J Lambert; Jiànróng Lǐ; Jun-Min Li; Ran Liu; Igor S Lukashevich; Robin M MacDiarmid; Piet Maes; Marco Marklewitz; Sergio H Marshall; Shin-Yi L Marzano; John W McCauley; Ali Mirazimi; Elke Mühlberger; Tomoyuki Nabeshima; Rayapati Naidu; Tomohide Natsuaki; Beatriz Navarro; José A Navarro; Yutaro Neriya; Sergey V Netesov; Gabriele Neumann; Norbert Nowotny; Márcio R T Nunes; Francisco M Ochoa-Corona; Tomoyuki Okada; Gustavo Palacios; Vicente Pallás; Anna Papa; Sofia Paraskevopoulou; Colin R Parrish; Alex Pauvolid-Corrêa; Janusz T Pawęska; Daniel R Pérez; Florian Pfaff; Richard K Plemper; Thomas S Postler; Lee O Rabbidge; Sheli R Radoshitzky; Pedro L Ramos-González; Marius Rehanek; Renato O Resende; Carina A Reyes; Thaís C S Rodrigues; Víctor Romanowski; Dennis Rubbenstroth; Luisa Rubino; Jonathan A Runstadler; Sead Sabanadzovic; Sabrina Sadiq; Maria S Salvato; Takahide Sasaya; Martin Schwemmle; Stephen R Sharpe; Mang Shi; Yoshifumi Shimomoto; Venkidusamy Kavi Sidharthan; Manuela Sironi; Sophie Smither; Jin-Won Song; Kirsten M Spann; Jessica R Spengler; Mark D Stenglein; Ayato Takada; Sawana Takeyama; Akio Tatara; Robert B Tesh; Natalie J Thornburg; Xin Tian; Nicole D Tischler; Yasuhiro Tomitaka; Keizō Tomonaga; Noël Tordo; Changchun Tu; Massimo Turina; Ioannis E Tzanetakis; Anna Maria Vaira; Bernadette van den Hoogen; Bert Vanmechelen; Nikos Vasilakis; Martin Verbeek; Susanne von Bargen; Jiro Wada; Victoria Wahl; Peter J Walker; Thomas B Waltzek; Anna E Whitfield; Yuri I Wolf; Han Xia; Evanthia Xylogianni; Hironobu Yanagisawa; Kazutaka Yano; Gongyin Ye; Zhiming Yuan; F Murilo Zerbini; Guilin Zhang; Song Zhang; Yong-Zhen Zhang; Lu Zhao; Arnfinn Lodden Økland

  The Journal of general virology, Aug. 2023

  
• The hidden diversity of ancient bornaviral sequences from X and P genes in vertebrate genomes.

  Bea Clarise B Garcia; Yahiro Mukai; Keizo Tomonaga; Masayuki Horie

  Virus evolution, 2023

  
• Contact-number-driven virus evolution: A multi-level modeling framework for the evolution of acute or persistent RNA virus infection

  Junya Sunagawa; Ryo Komorizono; Hyeongki Park; William S. Hart; Robin N. Thompson; Akiko Makino; Keizo Tomonaga; Shingo Iwami; Ryo Yamaguchi

  PLOS Computational Biology, 30 May 2023

  
• Genome-scale CRISPR‒Cas9 screen identifies novel host factors as potential therapeutic targets for SARS-CoV-2 infection

  Madoka Sakai; Yoshie Masuda; Yusuke Tarumoto; Naoyuki Aihara; Yugo Tsunoda; Michiko Iwata; Yumiko Kamiya; Ryo Komorizono; Takeshi Noda; Kosuke Yusa; Keizo Tomonaga; Akiko Makino

  07 Mar. 2023

  
• Efficacy of oligodendrocyte precursor cells as delivery vehicles for single-chain variable fragment to misfolded SOD1 in ALS rat model

  Sumio Minamiyama; Madoka Sakai; Yuko Yamaguchi; Makiko Kusui; Hideki Wada; Ryota Hikiami; Yoshitaka Tamaki; Megumi Asada-Utsugi; Akemi Shodai; Akiko Makino; Noriko Fujiwara; Takashi Ayaki; Takakuni Maki; Hitoshi Warita; Masashi Aoki; Keizo Tomonaga; Ryosuke Takahashi; Makoto Urushitani

  Molecular Therapy - Methods & Clinical Development, Feb. 2023, Peer-reviewed

  
• Large-scale investigation of zoonotic viruses in the era of high-throughput sequencing.

  Junna Kawasaki; Keizo Tomonaga; Masayuki Horie

  Microbiology and immunology, Jan. 2023

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• Ribavirin Treatment for Severe Schizophrenia with Anti-Borna Disease Virus 1 Antibodies 30 Years after Onset.

  Hidenori Matsunaga; Akio Fukumori; Kohji Mori; Takashi Morihara; Shunsuke Sato; Kyoko Kitauchi; Kanta Yanagida; Kazumi Taguchi; Tomoyuki Honda; Keizo Tomonaga

  Case reports in psychiatry, 2023

  
• Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing.

  Nicolas Tarbouriech; Florian Chenavier; Junna Kawasaki; Kamel Bachiri; Jean-Marie Bourhis; Pierre Legrand; Lily L Freslon; Estelle M N Laurent; Elsa Suberbielle; Rob W H Ruigrok; Keizo Tomonaga; Daniel Gonzalez-Dunia; Masayuki Horie; Etienne Coyaud; Thibaut Crépin

  Viruses, 26 Oct. 2022

  
• 2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

  Jens H. Kuhn; Scott Adkins; Sergey V. Alkhovsky; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Martina Bandte; Martin Beer; Nicolas Bejerman; Éric Bergeron; Nadine Biedenkopf; Laurent Bigarré; Carol D. Blair; Kim R. Blasdell; Steven B. Bradfute; Thomas Briese; Paul A. Brown; Rémy Bruggmann; Ursula J. Buchholz; Michael J. Buchmeier; Alexander Bukreyev; Felicity Burt; Carmen Büttner; Charles H. Calisher; Thierry Candresse; Jeremy Carson; Inmaculada Casas; Kartik Chandran; Rémi N. Charrel; Yuya Chiaki; Anya Crane; Mark Crane; Laurent Dacheux; Elena Dal Bó; Juan Carlos de la Torre; Xavier de Lamballerie; William M. de Souza; Rik L. de Swart; Nolwenn M. Dheilly; Nicholas Di Paola; Francesco Di Serio; Ralf G. Dietzgen; Michele Digiaro; J. Felix Drexler; W. Paul Duprex; Ralf Dürrwald; Andrew J. Easton; Toufic Elbeaino; Koray Ergünay; Guozhong Feng; Claudette Feuvrier; Andrew E. Firth; Anthony R. Fooks; Pierre B. H. Formenty; Juliana Freitas-Astúa; Selma Gago-Zachert; María Laura García; Adolfo García-Sastre; Aura R. Garrison; Scott E. Godwin; Jean-Paul J. Gonzalez; Joëlle Goüy de Bellocq; Anthony Griffiths; Martin H. Groschup; Stephan Günther; John Hammond; Jussi Hepojoki; Melanie M. Hierweger; Seiji Hongō; Masayuki Horie; Hidenori Horikawa; Holly R. Hughes; Adam J. Hume; Timothy H. Hyndman; Dàohóng Jiāng; Gilda B. Jonson; Sandra Junglen; Fujio Kadono; David G. Karlin; Boris Klempa; Jonas Klingström; Michel C. Koch; Hideki Kondō; Eugene V. Koonin; Jarmila Krásová; Mart Krupovic; Kenji Kubota; Ivan V. Kuzmin; Lies Laenen; Amy J. Lambert; Jiànróng Lǐ; Jun-Min Li; François Lieffrig; Igor S. Lukashevich; Dongsheng Luo; Piet Maes; Marco Marklewitz; Sergio H. Marshall; Shin-Yi L. Marzano; John W. McCauley; Ali Mirazimi; Peter G. Mohr; Nick J. G. Moody; Yasuaki Morita; Richard N. Morrison; Elke Mühlberger; Rayapati Naidu; Tomohide Natsuaki; José A. Navarro; Yutaro Neriya; Sergey V. Netesov; Gabriele Neumann; Norbert Nowotny; Francisco M. Ochoa-Corona; Gustavo Palacios; Laurane Pallandre; Vicente Pallás; Anna Papa; Sofia Paraskevopoulou; Colin R. Parrish; Alex Pauvolid-Corrêa; Janusz T. Pawęska; Daniel R. Pérez; Florian Pfaff; Richard K. Plemper; Thomas S. Postler; Françoise Pozet; Sheli R. Radoshitzky; Pedro L. Ramos-González; Marius Rehanek; Renato O. Resende; Carina A. Reyes; Víctor Romanowski; Dennis Rubbenstroth; Luisa Rubino; Artemis Rumbou; Jonathan A. Runstadler; Melanie Rupp; Sead Sabanadzovic; Takahide Sasaya; Heike Schmidt-Posthaus; Martin Schwemmle; Torsten Seuberlich; Stephen R. Sharpe; Mang Shi; Manuela Sironi; Sophie Smither; Jin-Won Song; Kirsten M. Spann; Jessica R. Spengler; Mark D. Stenglein; Ayato Takada; Robert B. Tesh; Jana Těšíková; Natalie J. Thornburg; Nicole D. Tischler; Yasuhiro Tomitaka; Keizō Tomonaga; Noël Tordo; Kenta Tsunekawa; Massimo Turina; Ioannis E. Tzanetakis; Anna Maria Vaira; Bernadette van den Hoogen; Bert Vanmechelen; Nikos Vasilakis; Martin Verbeek; Susanne von Bargen; Jiro Wada; Victoria Wahl; Peter J. Walker; Anna E. Whitfield; John V. Williams; Yuri I. Wolf; Junki Yamasaki; Hironobu Yanagisawa; Gongyin Ye; Yong-Zhen Zhang; Arnfinn Lodden Økland

  Archives of Virology, 28 Nov. 2022, Peer-reviewed

  
• Reverse Genetics and Artificial Replication Systems of Borna Disease Virus 1

  Takehiro Kanda; Keizo Tomonaga

  Viruses, 12 Oct. 2022

  
• A multicenter study to investigate the positive rate of SARS-CoV-2 in middle ear and mastoid specimens from otologic surgery patients.

  Hiroshi Yamazaki; Norio Yamamoto; Toru Sonoyama; Hayato Maruoka; Seiko Nasu; Akiko Makino; Keizo Tomonaga; Norifumi Shigemoto; Hiroki Ohge; Keizo Fujiwara; Shogo Shinohara; Sachio Takeno; Koichi Omori; Yasushi Naito

  Auris, nasus, larynx, 29 Jul. 2022

  
• Exogenous expression of both matrix protein and glycoprotein facilitates infectious viral particle production of Borna disease virus 1

  Takehiro Kanda; Madoka Sakai; Akiko Makino; Keizo Tomonaga

  Journal of General Virology, 12 Jul. 2022

  
• A comprehensive profiling of innate immune responses in Eptesicus bat cells.

  Hsien-Hen Lin; Masayuki Horie; Keizo Tomonaga

  Microbiology and immunology, Mar. 2022

  
• An endogenous bornavirus-like nucleoprotein in miniopterid bats retains the RNA-binding properties of the original viral protein.

  Yahiro Mukai; Masayuki Horie; Shohei Kojima; Junna Kawasaki; Ken Maeda; Keizo Tomonaga

  FEBS letters, Feb. 2022

  
• Waning of Anti-SARS-CoV-2 Spike Antibody Levels 100 to 200 Days after the Second Dose of the BNT162b2 Vaccine.

  Hidenori Matsunaga; Hidefumi Takeuchi; Yuichiro Oba; Satoshi Fujimi; Tomoyuki Honda; Keizo Tomonaga

  Vaccines, 24 Jan. 2022

  
• Stability of Borna disease virus-based episomal vector under physical and chemical stimulation.

  Mako Yanai; Madoka Sakai; Ryo Komorizono; Akiko Makino; Keizo Tomonaga

  Microbiology and immunology, Jan. 2022

  
• The mechanism underlying the organization of Borna disease virus inclusion bodies is unique among mononegaviruses

  Yuya Hirai; Keizo Tomonaga; Masayuki Horie

  24 May 2021

  
• 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.

  Jens H Kuhn; Scott Adkins; Bernard R Agwanda; Rim Al Kubrusli; Sergey V Alkhovsky; Gaya K Amarasinghe; Tatjana Avšič-Županc; María A Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J Ballinger; Christopher F Basler; Sina Bavari; Martin Beer; Nicolas Bejerman; Andrew J Bennett; Dennis A Bente; Éric Bergeron; Brian H Bird; Carol D Blair; Kim R Blasdell; Dag-Ragnar Blystad; Jamie Bojko; Wayne B Borth; Steven Bradfute; Rachel Breyta; Thomas Briese; Paul A Brown; Judith K Brown; Ursula J Buchholz; Michael J Buchmeier; Alexander Bukreyev; Felicity Burt; Carmen Büttner; Charles H Calisher; Mengji Cao; Inmaculada Casas; Kartik Chandran; Rémi N Charrel; Qi Cheng; Yuya Chiaki; Marco Chiapello; Il-Ryong Choi; Marina Ciuffo; J Christopher S Clegg; Ian Crozier; Elena Dal Bó; Juan Carlos de la Torre; Xavier de Lamballerie; Rik L de Swart; Humberto Debat; Nolwenn M Dheilly; Emiliano Di Cicco; Nicholas Di Paola; Francesco Di Serio; Ralf G Dietzgen; Michele Digiaro; Olga Dolnik; Michael A Drebot; J Felix Drexler; William G Dundon; W Paul Duprex; Ralf Dürrwald; John M Dye; Andrew J Easton; Hideki Ebihara; Toufic Elbeaino; Koray Ergünay; Hugh W Ferguson; Anthony R Fooks; Marco Forgia; Pierre B H Formenty; Jana Fránová; Juliana Freitas-Astúa; Jingjing Fu; Stephanie Fürl; Selma Gago-Zachert; George Fú Gāo; María Laura García; Adolfo García-Sastre; Aura R Garrison; Thomas Gaskin; Jean-Paul J Gonzalez; Anthony Griffiths; Tony L Goldberg; Martin H Groschup; Stephan Günther; Roy A Hall; John Hammond; Tong Han; Jussi Hepojoki; Roger Hewson; Jiang Hong; Ni Hong; Seiji Hongo; Masayuki Horie; John S Hu; Tao Hu; Holly R Hughes; Florian Hüttner; Timothy H Hyndman; M Ilyas; Risto Jalkanen; Dàohóng Jiāng; Gilda B Jonson; Sandra Junglen; Fujio Kadono; Karia H Kaukinen; Michael Kawate; Boris Klempa; Jonas Klingström; Gary Kobinger; Igor Koloniuk; Hideki Kondō; Eugene V Koonin; Mart Krupovic; Kenji Kubota; Gael Kurath; Lies Laenen; Amy J Lambert; Stanley L Langevin; Benhur Lee; Elliot J Lefkowitz; Eric M Leroy; Shaorong Li; Longhui Li; Jiànróng Lǐ; Huazhen Liu; Igor S Lukashevich; Piet Maes; William Marciel de Souza; Marco Marklewitz; Sergio H Marshall; Shin-Yi L Marzano; Sebastien Massart; John W McCauley; Michael Melzer; Nicole Mielke-Ehret; Kristina M Miller; Tobi J Ming; Ali Mirazimi; Gideon J Mordecai; Hans-Peter Mühlbach; Elke Mühlberger; Rayapati Naidu; Tomohide Natsuaki; José A Navarro; Sergey V Netesov; Gabriele Neumann; Norbert Nowotny; Márcio R T Nunes; Alejandro Olmedo-Velarde; Gustavo Palacios; Vicente Pallás; Bernadett Pályi; Anna Papa; Sofia Paraskevopoulou; Adam C Park; Colin R Parrish; David A Patterson; Alex Pauvolid-Corrêa; Janusz T Pawęska; Susan Payne; Carlotta Peracchio; Daniel R Pérez; Thomas S Postler; Liying Qi; Sheli R Radoshitzky; Renato O Resende; Carina A Reyes; Bertus K Rima; Gabriel Robles Luna; Víctor Romanowski; Paul Rota; Dennis Rubbenstroth; Luisa Rubino; Jonathan A Runstadler; Sead Sabanadzovic; Amadou Alpha Sall; Maria S Salvato; Rosemary Sang; Takahide Sasaya; Angela D Schulze; Martin Schwemmle; Mang Shi; Xiǎohóng Shí; Zhènglì Shí; Yoshifumi Shimomoto; Yukio Shirako; Stuart G Siddell; Peter Simmonds; Manuela Sironi; Guy Smagghe; Sophie Smither; Jin-Won Song; Kirsten Spann; Jessica R Spengler; Mark D Stenglein; David M Stone; Jari Sugano; Curtis A Suttle; Amy Tabata; Ayato Takada; Shigeharu Takeuchi; David P Tchouassi; Amy Teffer; Robert B Tesh; Natalie J Thornburg; Yasuhiro Tomitaka; Keizō Tomonaga; Noël Tordo; Baldwyn Torto; Jonathan S Towner; Shinya Tsuda; Changchun Tu; Massimo Turina; Ioannis E Tzanetakis; Janice Uchida; Tomio Usugi; Anna Maria Vaira; Marta Vallino; Bernadette van den Hoogen; Arvind Varsani; Nikos Vasilakis; Martin Verbeek; Susanne von Bargen; Jiro Wada; Victoria Wahl; Peter J Walker; Lin-Fa Wang; Guoping Wang; Yanxiang Wang; Yaqin Wang; Muhammad Waqas; Tàiyún Wèi; Shaohua Wen; Anna E Whitfield; John V Williams; Yuri I Wolf; Jiangxiang Wu; Lei Xu; Hironobu Yanagisawa; Caixia Yang; Zuokun Yang; F Murilo Zerbini; Lifeng Zhai; Yong-Zhen Zhang; Song Zhang; Jinguo Zhang; Zhe Zhang; Xueping Zhou

  Archives of virology, Dec. 2021

  
• Borna disease virus phosphoprotein triggers the organization of viral inclusion bodies by liquid-liquid phase separation.

  Yuya Hirai; Keizo Tomonaga; Masayuki Horie

  International journal of biological macromolecules, 01 Dec. 2021

  
• Hidden Viral Sequences in Public Sequencing Data and Warning for Future Emerging Diseases.

  Junna Kawasaki; Shohei Kojima; Keizo Tomonaga; Masayuki Horie

  mBio, 31 Aug. 2021

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• The Borna disease virus (BoDV) 2 nucleoprotein is a conspecific protein that enhances BoDV-1 RNA-dependent RNA polymerase activity.

  Takehiro Kanda; Masayuki Horie; Yumiko Komatsu; Keizo Tomonaga

  Journal of virology, 18 Aug. 2021

  
• BUD23-TRMT112 interacts with the L protein of Borna disease virus and mediates the chromosomal tethering of viral ribonucleoproteins.

  Bea Clarise B Garcia; Masayuki Horie; Shohei Kojima; Akiko Makino; Keizo Tomonaga

  Microbiology and immunology, 29 Jul. 2021

  
• ICTV Virus Taxonomy Profile: Bornaviridae.

  Dennis Rubbenstroth; Thomas Briese; Ralf Dürrwald; Masayuki Horie 堀江真行; Timothy H Hyndman; Jens H Kuhn; Norbert Nowotny; Susan Payne; Mark D Stenglein; Keizō Tomonaga 朝長啓造; Ictv Report Consortium

  The Journal of general virology, Jul. 2021

  
• A Human Endogenous Bornavirus-Like Nucleoprotein Encodes a Mitochondrial Protein Associated with Cell Viability.

  Kan Fujino; Masayuki Horie; Shohei Kojima; Sae Shimizu; Aya Nabekura; Hiroko Kobayashi; Akiko Makino; Tomoyuki Honda; Keizo Tomonaga

  Journal of virology, 24 Jun. 2021

  
• 100-My history of bornavirus infections hidden in vertebrate genomes.

  Junna Kawasaki; Shohei Kojima; Yahiro Mukai; Keizo Tomonaga; Masayuki Horie

  Proceedings of the National Academy of Sciences of the United States of America, 18 May 2021

  
• Characterization of an active LINE-1 in the naked mole-rat genome.

  Shunichi Yamaguchi; Shizuka Nohara; Yuki Nishikawa; Yusuke Suzuki; Yoshimi Kawamura; Kyoko Miura; Keizo Tomonaga; Keiji Ueda; Tomoyuki Honda

  Scientific reports, 11 Mar. 2021

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• Radioligand Assay-Based Detection of Antibodies against SARS-CoV-2 in Hospital Workers Treating Patients with Severe COVID-19 in Japan.

  Hidenori Matsunaga; Akiko Makino; Yasuhiro Kato; Teruaki Murakami; Yuta Yamaguchi; Atsushi Kumanogoh; Yuichiro Oba; Satoshi Fujimi; Tomoyuki Honda; Keizo Tomonaga

  Viruses, 23 Feb. 2021

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• Virus-like insertions with sequence signatures similar to those of endogenous nonretroviral RNA viruses in the human genome.

  Shohei Kojima; Kohei Yoshikawa; Jumpei Ito; So Nakagawa; Nicholas F Parrish; Masayuki Horie; Shuichi Kawano; Keizo Tomonaga

  Proceedings of the National Academy of Sciences of the United States of America, 02 Feb. 2021

  
• Identification of a reptile lyssavirus in Anolis allogus provided novel insights into lyssavirus evolution.

  Masayuki Horie; Hiroshi Akashi; Masakado Kawata; Keizo Tomonaga

  Virus genes, Feb. 2021

  
• Identification of novel avian and mammalian deltaviruses provides new insights into deltavirus evolution.

  Masashi Iwamoto; Yukino Shibata; Junna Kawasaki; Shohei Kojima; Yung-Tsung Li; Shingo Iwami; Masamichi Muramatsu; Hui-Lin Wu; Kazuhiro Wada; Keizo Tomonaga; Koichi Watashi; Masayuki Horie

  Virus evolution, Jan. 2021

  
• Optimal Expression of the Envelope Glycoprotein of Orthobornaviruses Determines the Production of Mature Virus Particles.

  Madoka Sakai; Yoko Fujita; Ryo Komorizono; Takehiro Kanda; Yumiko Komatsu; Takeshi Noda; Keizo Tomonaga; Akiko Makino

  Journal of virology, 02 Dec. 2020

  
• 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.

  Jens H Kuhn; Scott Adkins; Daniela Alioto; Sergey V Alkhovsky; Gaya K Amarasinghe; Simon J Anthony; Tatjana Avšič-Županc; María A Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J Ballinger; Tomáš Bartonička; Christopher Basler; Sina Bavari; Martin Beer; Dennis A Bente; Éric Bergeron; Brian H Bird; Carol Blair; Kim R Blasdell; Steven B Bradfute; Rachel Breyta; Thomas Briese; Paul A Brown; Ursula J Buchholz; Michael J Buchmeier; Alexander Bukreyev; Felicity Burt; Nihal Buzkan; Charles H Calisher; Mengji Cao; Inmaculada Casas; John Chamberlain; Kartik Chandran; Rémi N Charrel; Biao Chen; Michela Chiumenti; Il-Ryong Choi; J Christopher S Clegg; Ian Crozier; John V da Graça; Elena Dal Bó; Alberto M R Dávila; Juan Carlos de la Torre; Xavier de Lamballerie; Rik L de Swart; Patrick L Di Bello; Nicholas Di Paola; Francesco Di Serio; Ralf G Dietzgen; Michele Digiaro; Valerian V Dolja; Olga Dolnik; Michael A Drebot; Jan Felix Drexler; Ralf Dürrwald; Lucie Dufkova; William G Dundon; W Paul Duprex; John M Dye; Andrew J Easton; Hideki Ebihara; Toufic Elbeaino; Koray Ergünay; Jorlan Fernandes; Anthony R Fooks; Pierre B H Formenty; Leonie F Forth; Ron A M Fouchier; Juliana Freitas-Astúa; Selma Gago-Zachert; George Fú Gāo; María Laura García; Adolfo García-Sastre; Aura R Garrison; Aiah Gbakima; Tracey Goldstein; Jean-Paul J Gonzalez; Anthony Griffiths; Martin H Groschup; Stephan Günther; Alexandro Guterres; Roy A Hall; John Hammond; Mohamed Hassan; Jussi Hepojoki; Satu Hepojoki; Udo Hetzel; Roger Hewson; Bernd Hoffmann; Seiji Hongo; Dirk Höper; Masayuki Horie; Holly R Hughes; Timothy H Hyndman; Amara Jambai; Rodrigo Jardim; Dàohóng Jiāng; Qi Jin; Gilda B Jonson; Sandra Junglen; Serpil Karadağ; Karen E Keller; Boris Klempa; Jonas Klingström; Gary Kobinger; Hideki Kondō; Eugene V Koonin; Mart Krupovic; Gael Kurath; Ivan V Kuzmin; Lies Laenen; Robert A Lamb; Amy J Lambert; Stanley L Langevin; Benhur Lee; Elba R S Lemos; Eric M Leroy; Dexin Li; Jiànróng Lǐ; Mifang Liang; Wénwén Liú; Yàn Liú; Igor S Lukashevich; Piet Maes; William Marciel de Souza; Marco Marklewitz; Sergio H Marshall; Giovanni P Martelli; Robert R Martin; Shin-Yi L Marzano; Sébastien Massart; John W McCauley; Nicole Mielke-Ehret; Angelantonio Minafra; Maria Minutolo; Ali Mirazimi; Hans-Peter Mühlbach; Elke Mühlberger; Rayapati Naidu; Tomohide Natsuaki; Beatriz Navarro; José A Navarro; Sergey V Netesov; Gabriele Neumann; Norbert Nowotny; Márcio R T Nunes; Are Nylund; Arnfinn L Økland; Renata C Oliveira; Gustavo Palacios; Vicente Pallas; Bernadett Pályi; Anna Papa; Colin R Parrish; Alex Pauvolid-Corrêa; Janusz T Pawęska; Susan Payne; Daniel R Pérez; Florian Pfaff; Sheli R Radoshitzky; Aziz-Ul Rahman; Pedro L Ramos-González; Renato O Resende; Carina A Reyes; Bertus K Rima; Víctor Romanowski; Gabriel Robles Luna; Paul Rota; Dennis Rubbenstroth; Jonathan A Runstadler; Daniel Ruzek; Sead Sabanadzovic; Jiří Salát; Amadou Alpha Sall; Maria S Salvato; Kamil Sarpkaya; Takahide Sasaya; Martin Schwemmle; Muhammad Z Shabbir; Xiǎohóng Shí; Zhènglì Shí; Yukio Shirako; Peter Simmonds; Jana Širmarová; Manuela Sironi; Sophie Smither; Teemu Smura; Jin-Won Song; Kirsten M Spann; Jessica R Spengler; Mark D Stenglein; David M Stone; Petra Straková; Ayato Takada; Robert B Tesh; Natalie J Thornburg; Keizō Tomonaga; Noël Tordo; Jonathan S Towner; Massimo Turina; Ioannis Tzanetakis; Rainer G Ulrich; Anna Maria Vaira; Bernadette van den Hoogen; Arvind Varsani; Nikos Vasilakis; Martin Verbeek; Victoria Wahl; Peter J Walker; Hui Wang; Jianwei Wang; Xifeng Wang; Lin-Fa Wang; Tàiyún Wèi; Heather Wells; Anna E Whitfield; John V Williams; Yuri I Wolf; Zhìqiáng Wú; Xin Yang; Xīnglóu Yáng; Xuejie Yu; Natalya Yutin; F Murilo Zerbini; Tong Zhang; Yong-Zhen Zhang; Guohui Zhou; Xueping Zhou

  Archives of virology, Dec. 2020

  
• Evolutionary Selection of the Nuclear Localization Signal in the Viral Nucleoprotein Leads to Host Adaptation of the Genus Orthobornavirus.

  Ryo Komorizono; Yukiko Sassa; Masayuki Horie; Akiko Makino; Keizo Tomonaga

  Viruses, 11 Nov. 2020

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• Modeling Borna Disease Virus In Vitro Spread Reveals the Mode of Antiviral Effect Conferred by an Endogenous Bornavirus-Like Element.

  Kwang Su Kim; Yusuke Yamamoto; Shinji Nakaoka; Keizo Tomonaga; Shingo Iwami; Tomoyuki Honda

  Journal of virology, 14 Oct. 2020

  
• Reverse genetics approaches of Borna disease virus: applications in development of viral vectors and preventive vaccines.

  Yumiko Komatsu; Keizo Tomonaga

  Current opinion in virology, 10 Jul. 2020, Peer-reviewed

  
• Production of high-titer transmission-defective RNA virus-based episomal vector using tangential flow filtration.

  Yumiko Komatsu; Yoji Kakuya; Keizo Tomonaga

  Microbiology and immunology, 09 Jul. 2020, Peer-reviewed

  
• In vivo biodistribution analysis of transmission competent and defective RNA virus-based episomal vector.

  Yumiko Komatsu; Chiaki Tanaka; Ryo Komorizono; Keizo Tomonaga

  Scientific reports, 03 Apr. 2020, Peer-reviewed

  
• ADAR2 Is Involved in Self and Nonself Recognition of Borna Disease Virus Genomic RNA in the Nucleus.

  Mako Yanai; Shohei Kojima; Madoka Sakai; Ryo Komorizono; Keizo Tomonaga; Akiko Makino

  Journal of virology, 28 Feb. 2020, Peer-reviewed

  
• Differential roles of two DDX17 isoforms in the formation of membraneless organelles.

  Yuya Hirai; Eisuke Domae; Yoshihiro Yoshikawa; Keizo Tomonaga

  Journal of biochemistry, 17 Feb. 2020, Peer-reviewed

  
• Development of a reverse transcription-loop-mediated isothermal amplification assay for the detection of parrot bornavirus 4.

  Komorizono R; Tomonaga K; Makino A

  Journal of virological methods, Jan. 2020, Peer-reviewed

  
• Neo-virology: The raison d'etre of viruses.

  Tokiko Watanabe; Nobuhiro Suzuki; Keizo Tomonaga; Hirofumi Sawa; Yoshiharu Matsuura; Yasushi Kawaguchi; Hideki Takahashi; Keizo Nagasaki; Yoshihiro Kawaoka

  Virus research, Dec. 2019, Peer-reviewed

  
• Identification of a distinct lineage of aviadenovirus from crane feces.

  Yahiro Mukai; Yuriko Tomita; Kirill Kryukov; So Nakagawa; Makoto Ozawa; Tsutomu Matsui; Keizo Tomonaga; Tadashi Imanishi; Yoshihiro Kawaoka; Tokiko Watanabe; Masayuki Horie

  Virus genes, Dec. 2019, Peer-reviewed

  
• RNA Virus-Based Episomal Vector with a Fail-Safe Switch Facilitating Efficient Genetic Modification and Differentiation of iPSCs.

  Yumiko Komatsu; Dan Takeuchi; Tomoya Tokunaga; Hidetoshi Sakurai; Akiko Makino; Tomoyuki Honda; Yasuhiro Ikeda; Keizo Tomonaga

  Molecular therapy. Methods & clinical development, 13 Sep. 2019, Peer-reviewed

  
• Taxonomy of the order Mononegavirales: update 2019.

  Gaya K Amarasinghe; María A Ayllón; Yīmíng Bào; Christopher F Basler; Sina Bavari; Kim R Blasdell; Thomas Briese; Paul A Brown; Alexander Bukreyev; Anne Balkema-Buschmann; Ursula J Buchholz; Camila Chabi-Jesus; Kartik Chandran; Chiara Chiapponi; Ian Crozier; Rik L de Swart; Ralf G Dietzgen; Olga Dolnik; Jan F Drexler; Ralf Dürrwald; William G Dundon; W Paul Duprex; John M Dye; Andrew J Easton; Anthony R Fooks; Pierre B H Formenty; Ron A M Fouchier; Juliana Freitas-Astúa; Anthony Griffiths; Roger Hewson; Masayuki Horie; Timothy H Hyndman; Dàohóng Jiāng; Elliott W Kitajima; Gary P Kobinger; Hideki Kondō; Gael Kurath; Ivan V Kuzmin; Robert A Lamb; Antonio Lavazza; Benhur Lee; Davide Lelli; Eric M Leroy; Jiànróng Lǐ; Piet Maes; Shin-Yi L Marzano; Ana Moreno; Elke Mühlberger; Sergey V Netesov; Norbert Nowotny; Are Nylund; Arnfinn L Økland; Gustavo Palacios; Bernadett Pályi; Janusz T Pawęska; Susan L Payne; Alice Prosperi; Pedro Luis Ramos-González; Bertus K Rima; Paul Rota; Dennis Rubbenstroth; Mǎng Shī; Peter Simmonds; Sophie J Smither; Enrica Sozzi; Kirsten Spann; Mark D Stenglein; David M Stone; Ayato Takada; Robert B Tesh; Keizō Tomonaga; Noël Tordo; Jonathan S Towner; Bernadette van den Hoogen; Nikos Vasilakis; Victoria Wahl; Peter J Walker; Lin-Fa Wang; Anna E Whitfield; John V Williams; F Murilo Zerbini; Tāo Zhāng; Yong-Zhen Zhang; Jens H Kuhn

  Archives of virology, Jul. 2019, Peer-reviewed

  
• Taxonomy of the order Mononegavirales: second update 2018.

  Piet Maes; Gaya K Amarasinghe; María A Ayllón; Christopher F Basler; Sina Bavari; Kim R Blasdell; Thomas Briese; Paul A Brown; Alexander Bukreyev; Anne Balkema-Buschmann; Ursula J Buchholz; Kartik Chandran; Ian Crozier; Rik L de Swart; Ralf G Dietzgen; Olga Dolnik; Leslie L Domier; Jan F Drexler; Ralf Dürrwald; William G Dundon; W Paul Duprex; John M Dye; Andrew J Easton; Anthony R Fooks; Pierre B H Formenty; Ron A M Fouchier; Juliana Freitas-Astúa; Elodie Ghedin; Anthony Griffiths; Roger Hewson; Masayuki Horie; Julia L Hurwitz; Timothy H Hyndman; Dàohóng Jiāng; Gary P Kobinger; Hideki Kondō; Gael Kurath; Ivan V Kuzmin; Robert A Lamb; Benhur Lee; Eric M Leroy; Jiànróng Lǐ; Shin-Yi L Marzano; Elke Mühlberger; Sergey V Netesov; Norbert Nowotny; Gustavo Palacios; Bernadett Pályi; Janusz T Pawęska; Susan L Payne; Bertus K Rima; Paul Rota; Dennis Rubbenstroth; Peter Simmonds; Sophie J Smither; Qisheng Song; Timothy Song; Kirsten Spann; Mark D Stenglein; David M Stone; Ayato Takada; Robert B Tesh; Keizō Tomonaga; Noël Tordo; Jonathan S Towner; Bernadette van den Hoogen; Nikos Vasilakis; Victoria Wahl; Peter J Walker; David Wang; Lin-Fa Wang; Anna E Whitfield; John V Williams; Gōngyín Yè; F Murilo Zerbini; Yong-Zhen Zhang; Jens H Kuhn

  Archives of virology, Apr. 2019, Peer-reviewed

  
• Intracellular dynamics of actin affects Borna disease virus replication in the nucleus.

  Hirai Y; Domae E; Yoshikawa Y; Okamura H; Makino A; Tomonaga K

  Virus research, Apr. 2019, Peer-reviewed

  
• Splicing-Dependent Subcellular Targeting of Borna Disease Virus Nucleoprotein Isoforms.

  Kojima S; Sato R; Yanai M; Komatsu Y; Horie M; Igarashi M; Tomonaga K

  Journal of virology, Mar. 2019, Peer-reviewed

  
• "Integration of viral sequences into eukaryotic host genomes: legacy of ancient infections".

  Tomonaga K; Suzuki N; Berkhout B

  Virus research, Mar. 2019, Peer-reviewed

  
• Development of an RNA Virus-Based Episomal Vector Capable of Switching Transgene Expression.

  Yusuke Yamamoto; Keizo Tomonaga; Tomoyuki Honda

  Frontiers in microbiology, 2019, Peer-reviewed

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• Two Neuropsychiatric Cases Seropositive for Bornavirus Improved by Ribavirin

  Hidenori Matsunaga; Akio Fukumori; Kohji Mori; Tomoyuki Honda; Takeshi Uema; Keizo Tomonaga

  Japanese Journal of Infectious Diseases, 30 Sep. 2018, Peer-reviewed

  
• Taxonomy of the order Mononegavirales: update 2018.

  Gaya K Amarasinghe; Nidia G Aréchiga Ceballos; Ashley C Banyard; Christopher F Basler; Sina Bavari; Andrew J Bennett; Kim R Blasdell; Thomas Briese; Alexander Bukreyev; Yíngyún Caì; Charles H Calisher; Cristine Campos Lawson; Kartik Chandran; Colin A Chapman; Charles Y Chiu; Kang-Seuk Choi; Peter L Collins; Ralf G Dietzgen; Valerian V Dolja; Olga Dolnik; Leslie L Domier; Ralf Dürrwald; John M Dye; Andrew J Easton; Hideki Ebihara; Juan E Echevarría; Anthony R Fooks; Pierre B H Formenty; Ron A M Fouchier; Conrad M Freuling; Elodie Ghedin; Tony L Goldberg; Roger Hewson; Masayuki Horie; Timothy H Hyndman; Dàohóng Jiāng; Robert Kityo; Gary P Kobinger; Hideki Kondō; Eugene V Koonin; Mart Krupovic; Gael Kurath; Robert A Lamb; Benhur Lee; Eric M Leroy; Piet Maes; Andrea Maisner; Denise A Marston; Sunil Kumar Mor; Thomas Müller; Elke Mühlberger; Víctor Manuel Neira Ramírez; Sergey V Netesov; Terry Fei Fan Ng; Norbert Nowotny; Gustavo Palacios; Jean L Patterson; Janusz T Pawęska; Susan L Payne; Karla Prieto; Bertus K Rima; Paul Rota; Dennis Rubbenstroth; Martin Schwemmle; Stuart Siddell; Sophie J Smither; Qisheng Song; Timothy Song; Mark D Stenglein; David M Stone; Ayato Takada; Robert B Tesh; Luciano Matsumiya Thomazelli; Keizō Tomonaga; Noël Tordo; Jonathan S Towner; Nikos Vasilakis; Sonia Vázquez-Morón; Claudio Verdugo; Viktor E Volchkov; Victoria Wahl; Peter J Walker; David Wang; Lin-Fa Wang; James F X Wellehan; Michael R Wiley; Anna E Whitfield; Yuri I Wolf; Gōngyín Yè; Yǒng-Zhèn Zhāng; Jens H Kuhn

  Archives of virology, Aug. 2018, Peer-reviewed

  
• Systematic estimation of insertion dates of endogenous bornavirus-like elements in vesper bats.

  Mukai Y; Horie M; Tomonaga K

  The Journal of veterinary medical science, Aug. 2018, Peer-reviewed

  
• Prevalence of antibodies against Borna disease virus proteins in Japanese children with autism spectrum disorder.

  Tomoyuki Honda; Kozue Sofuku; Hidenori Matsunaga; Masaya Tachibana; Ikuko Mohri; Masako Taniike; Keizo Tomonaga

  Microbiology and immunology, 22 May 2018, Peer-reviewed

  
• Degradation of amyloid β peptide by neprilysin expressed from Borna disease virus vector.

  Sakai M; Ueda S; Daito T; Asada-Utsugi M; Komatsu Y; Kinoshita A; Maki T; Kuzuya A; Takahashi R; Makino A; Tomonaga K

  Microbiology and immunology, May 2018, Peer-reviewed

  
• A Viral (Arc)hive for Metazoan Memory

  Nicholas F. Parrish; Keizo Tomonaga

  Cell, 11 Jan. 2018, Peer-reviewed

  
• Paleovirology of bornaviruses: What can be learned from molecular fossils of bornaviruses

  Masayuki Horie; Keizo Tomonaga

  Virus Research, 2018, Peer-reviewed

  
• Regnase-1 and Roquin Nonredundantly Regulate Th1 Differentiation Causing Cardiac Inflammation and Fibrosis

  Xiaotong Cui; Takashi Mino; Masanori Yoshinaga; Yoshinari Nakatsuka; Fabian Hia; Daichi Yamasoba; Tohru Tsujimura; Keizo Tomonaga; Yutaka Suzuki; Takuya Uehata; Osamu Takeuchi

  JOURNAL OF IMMUNOLOGY, Dec. 2017, Peer-reviewed

  
• Linkage between the leader sequence and leader RNA production in Borna disease virus-infected cells

  Tomoyuki Honda; Kozue Sofuku; Shohei Kojima; Yusuke Yamamoto; Naohiro Ohtaki; Keizo Tomonaga

  VIROLOGY, Oct. 2017, Peer-reviewed

  
• Generation of a non-transmissive Borna disease virus vector lacking both matrix and glycoprotein genes

  Kan Fujino; Yusuke Yamamoto; Takuji Daito; Akiko Makino; Tomoyuki Honda; Keizo Tomonaga

  MICROBIOLOGY AND IMMUNOLOGY, Sep. 2017, Peer-reviewed

  
• Detection of Antibodies against Borna Disease Virus Proteins in an Autistic Child and Her Mother (vol 70, pg 225, 2017)

  Tomoyuki Honda; Kozue Sofuku; Hidenori Matsunaga; Masaya Tachibana; Ikuko Mohri; Masako Taniike; Keizo Tomonaga

  JAPANESE JOURNAL OF INFECTIOUS DISEASES, Sep. 2017, Peer-reviewed

  
• Taxonomy of the order Mononegavirales: update 2017

  Gaya K. Amarasinghe; Yiming Bao; Christopher F. Basler; Sina Bavari; Martin Beer; Nicolas Bejerman; Kim R. Blasdell; Alisa Bochnowski; Thomas Briese; Alexander Bukreyev; Charles H. Calisher; Kartik Chandran; Peter L. Collins; Ralf G. Dietzgen; Olga Dolnik; Ralf Duerrwald; John M. Dye; Andrew J. Easton; Hideki Ebihara; Qi Fang; Pierre Formenty; Ron A. M. Fouchier; Elodie Ghedin; Robert M. Harding; Roger Hewson; Colleen M. Higgins; Jian Hong; Masayuki Horie; Anthony P. James; Daohong JiAng; Gary P. Kobinger; Hideki Kondo; Gael Kurath; Robert A. Lamb; Benhur Lee; Eric M. Leroy; Ming Li; Andrea Maisner; Elke Muhlberger; Sergey V. Netesov; Norbert Nowotny; Jean L. Patterson; Susan L. Payne; Janusz T. Paweska; Michael N. Pearson; Rick E. Randall; Peter A. Revill; Bertus K. Rima; Paul Rota; Dennis Rubbenstroth; Martin Schwemmle; Sophie J. Smither; Qisheng Song; David M. Stone; Ayato Takada; Calogero Terregino; Robert B. Tesh; Keizo Tomonaga; Noel Tordo; Jonathan S. Towner; Nikos Vasilakis; Viktor E. Volchkov; Victoria Wahl-Jensen; Peter J. Walker; Beibei Wang; David Wang; Fei Wang; Lin-Fa Wang; John H. Werren; Anna E. Whitfield; Zhichao Yan; Gongyin Ye; Jens H. Kuhn

  ARCHIVES OF VIROLOGY, Aug. 2017, Peer-reviewed

  
• Dual function of the nuclear export signal of the Borna disease virus nucleoprotein in nuclear export activity and binding to viral phosphoprotein

  Mako Yanai; Madoka Sakai; Akiko Makino; Keizo Tomonaga

  VIROLOGY JOURNAL, Jul. 2017, Peer-reviewed

  
• Antiviral activity of favipiravir (T-705) against mammalian and avian bornaviruses

  Tomoya Tokunaga; Yusuke Yamamoto; Madoka Sakai; Keizo Tomonaga; Tomoyuki Honda

  ANTIVIRAL RESEARCH, Jul. 2017, Peer-reviewed

  
• 突然の健忘で発症し精神症状等を合併した抗ボルナウイルス抗体陽性の2症例

  松永 秀典; 陸 馨仙; 福本 素由己; 金井 講治; 近江 翼; 大村 夕美; 本田 知之; 朝長 啓造

  精神神経学雑誌, Jun. 2017, Peer-reviewed

  
• Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials

  Thomas S. Postler; Anna N. Clawson; Gaya K. Amarasinghe; Christopher F. Basler; Sbina Bavari; Maria Benko; Kim R. Blasdell; Thomas Briese; Michael J. Buchmeier; Alexander Bukreyev; Charles H. Calisher; Kartik Chandran; Remi Charrel; Christopher S. Clegg; Peter L. Collins; Juan Carlos de la Torre; Joseph L. Derisi; Ralf G. Dietzgen; Olga Dolnik; Ralf Duerrwald; John M. Dye; Andrew J. Easton; Sebastian Emonet; Pierre Formenty; Ron A. M. Fouchier; Elodie Ghedin; Jean-Paul Gonzalez; Balazs Harrach; Roger Hewson; Masayuki Horie; Daohong Jiang; Gary Kobinger; Hideki Kondo; Andrew M. Kropinski; Mart Krupovic; Gael Kurath; Robert A. Lamb; Eric M. Leroy; Igor S. Lukashevich; Andrea Maisner; Arcady R. Mushegian; Sergey V. Netesov; Norbert Nowotny; Jean L. Patterson; Susan L. Payne; Janusz T. Paweska; Clarence J. Peters; Sheli R. Radoshitzky; Bertus K. Rima; Victor Romanowski; Dennis Rubbenstroth; Sead Sabanadzovic; Helene Sanfacon; Maria S. Salvato; Martin Schwemmle; Sophie J. Smither; Mark D. Stenglein; David M. Stone; Ayato Takada; Robert B. Tesh; Keizo Tomonaga; Noel Tordo; Jonathan S. Towner; Nikos Vasilakis; Viktor E. Volchkov; Victoria Wahl-Jensen; Peter J. Walker; Lin-Fa Wang; Arvind Varsani; Anna E. Whitfield; F. Murilo Zerbini; Jens H. Kuhn

  SYSTEMATIC BIOLOGY, May 2017, Peer-reviewed

  
• Detection of Antibodies against Borna Disease Virus Proteins in an Autistic Child and Her Mother

  Tomoyuki Honda; Kozue Sofuku; Hidenori Matsunaga; Masaya Tachibana; Ikuko Mohri; Masako Taniike; Keizo Tomonaga

  JAPANESE JOURNAL OF INFECTIOUS DISEASES, Mar. 2017, Peer-reviewed

  
• Borna Disease Virus Assembles Porous Cage-like Viral Factories in the Nucleus

  Yuya Hirai; Yasuhiro Hirano; Atsushi Matsuda; Yasushi Hiraoka; Tomoyuki Honda; Keizo Tomonaga

  JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 2016, Peer-reviewed

  
• ドイツで死亡した3人の脳炎患者から発見されたカワリリスボルナウイルス(VSBV-1)に対する抗体測定の試み

  松永 秀典; 本田 知之; 近江 翼; 陸 馨仙; 福本 素由己; 金井 講治; 大村 夕美; 朝長 啓造

  NEUROINFECTION, Sep. 2016

  
• Taxonomy of the order Mononegavirales: update 2016

  Claudio L. Afonso; Gaya K. Amarasinghe; Krisztian Banyai; Yiming Bao; Christopher F. Basler; Sina Bavari; Nicolas Bejerman; Kim R. Blasdell; Francois-Xavier Briand; Thomas Briese; Alexander Bukreyev; Charles H. Calisher; Kartik Chandran; Jiasen Cheng; Anna N. Clawson; Peter L. Collins; Ralf G. Dietzgen; Olga Dolnik; Leslie L. Domier; Ralf Duerrwald; John M. Dye; Andrew J. Easton; Hideki Ebihara; Szilvia L. Farkas; Juliana Freitas-Astua; Pierre Formenty; Ron A. M. Fouchier; Yanping Fu; Elodie Ghedin; Michael M. Goodin; Roger Hewson; Masayuki Horie; Timothy H. Hyndman; Daohong Jiang; Elliot W. Kitajima; Gary P. Kobinger; Hideki Kondo; Gael Kurath; Robert A. Lamb; Sergio Lenardon; Eric M. Leroy; Ci-Xiu Li; Xian-Dan Lin; Lijiang Liu; Ben Longdon; Szilvia Marton; Andrea Maisner; Elke Muhlberger; Sergey V. Netesov; Norbert Nowotny; Jean L. Patterson; Susan L. Payne; Janusz T. Paweska; Rick E. Randall; Bertus K. Rima; Paul Rota; Dennis Rubbenstroth; Martin Schwemmle; Mang Shi; Sophie J. Smither; Mark D. Stenglein; David M. Stone; Ayato Takada; Calogero Terregino; Robert B. Tesh; Jun-Hua Tian; Keizo Tomonaga; Noel Tordo; Jonathan S. Towner; Nikos Vasilakis; Martin Verbeek; Viktor E. Volchkov; Victoria Wahl-Jensen; John A. Walsh; Peter J. Walker; David Wang; Lin-Fa Wang; Thierry Wetzel; Anna E. Whitfield; Jiatao Xie; Kwok-Yung Yuen; Yong-Zhen Zhang; Jens H. Kuhn

  ARCHIVES OF VIROLOGY, Aug. 2016, Peer-reviewed

  
• Endogenized viral sequences in mammals

  Nicholas F. Parrish; Keizo Tomonaga

  CURRENT OPINION IN MICROBIOLOGY, Jun. 2016, Peer-reviewed

  
• Sequence determination of a new parrot bornavirus-5 strain in Japan: implications of clade-specific sequence diversity in the regions interacting with host factors

  Ryo Komorizono; Akiko Makino; Masayuki Horie; Tomoyuki Honda; Keizo Tomonaga

  MICROBIOLOGY AND IMMUNOLOGY, Jun. 2016, Peer-reviewed

  
• An RNA-dependent RNA polymerase gene in bat genomes derived from an ancient negative-strand RNA virus

  Masayuki Horie; Yuki Kobayashi; Tomoyuki Honda; Kan Fujino; Takumi Akasaka; Claudia Kohl; Gudrun Wibbelt; Kristin Muehldorfer; Andreas Kurth; Marcel A. Mueller; Victor M. Corman; Nadine Gillich; Yoshiyuki Suzuki; Martin Schwemmle; Keizo Tomonaga

  SCIENTIFIC REPORTS, May 2016, Peer-reviewed

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• Long-term expression of miRNA for RNA interference using a novel vector system based on a negative-strand RNA virus

  Tomoyuki Honda; Yusuke Yamamoto; Takuji Daito; Yusuke Matsumoto; Akiko Makino; Keizo Tomonaga

  SCIENTIFIC REPORTS, May 2016, Peer-reviewed

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• A novel intranuclear RNA vector system for long-term stem cell modification

  Y. Ikeda; A. Makino; W. E. Matchett; S. J. Holditch; B. Lu; A. B. Dietz; K. Tomonaga

  GENE THERAPY, Mar. 2016, Peer-reviewed

  
• Isolation of avian bornaviruses from psittacine birds using QT6 quail cells in Japan

  Masayuki Horie; Yukiko Sassa; Haruko Iki; Kazumasa Ebisawa; Hideto Fukushi; Tokuma Yanai; Keizo Tomonaga

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Feb. 2016, Peer-reviewed

  
• Influenza A Virus-Induced Expression of a GalNAc Transferase, GALNT3, via MicroRNAs Is Required for Enhanced Viral Replication

  Shoko Nakamura; Masayuki Horie; Tomo Daidoji; Tomoyuki Honda; Mayo Yasugi; Atsushi Kuno; Toshihisa Komori; Daisuke Okuzaki; Hisashi Narimatsu; Takaaki Nakaya; Keizo Tomonaga

  JOURNAL OF VIROLOGY, Feb. 2016, Peer-reviewed

  
• ボルナウイルスとバイオセーフティ

  牧野晶子; 朝長 啓造

  日本バイオセーフティ学会ニュースレター, 2016, Peer-reviewed, Invited

  
• Possible roles of endogenous RNA virus elements in RNA virus infection.

  Honda T; Tomonaga K

  Uirusu, 2016, Peer-reviewed

  
• Endogenous non-retroviral RNA virus elements evidence a novel type of antiviral immunity

  Tomoyuki Honda; Keizo Tomonaga

  Mobile Genetic Elements, 2016, Peer-reviewed

  
• piRNAs derived from ancient viral processed pseudogenes as transgenerational sequence-specific immune memory in mammals

  Nicholas F. Parrish; Kan Fujino; Yusuke Shiromoto; Yuka W. Iwasaki; Hongseok Ha; Jinchuan Xing; Akiko Makino; Satomi Kuramochi-Miyagawa; Toru Nakano; Haruhiko Siomi; Tomoyuki Honda; Keizo Tomonaga

  RNA, Oct. 2015, Peer-reviewed

  
• Parrot bornavirus-2 and-4 RNA detected in wild bird samples in Japan are phylogenetically adjacent to those found in pet birds in Japan

  Yukiko Sassa; Vuong Nghia Bui; Keisuke Saitoh; Yukiko Watanabe; Satoshi Koyama; Daiji Endoh; Masayuki Horie; Keizo Tomonaga; Tetsuya Furuya; Makoto Nagai; Tsutomu Omatsu; Kunitoshi Imai; Haruko Ogawa; Tetsuya Mizutani

  VIRUS GENES, Oct. 2015, Peer-reviewed

  
• X-linked RNA-binding motif protein (RBMX) is required for the maintenance of Borna disease virus nuclear viral factories

  Yuya Hirai; Tomoyuki Honda; Akiko Makino; Yuzo Watanabe; Keizo Tomonaga

  JOURNAL OF GENERAL VIROLOGY, Oct. 2015, Peer-reviewed

  
• Intranuclear persistent infection of Borna disease virus

  Makino A; Tomonaga K

  ANTIBIOTICS & CHEMOTHERAPY, Sep. 2015, Invited

  
• Transcription Profiling Demonstrates Epigenetic Control of Non-retroviral RNA Virus-Derived Elements in the Human Genome

  Kozue Sofuku; Nicholas F. Parrish; Tomoyuki Honda; Keizo Tomonaga

  CELL REPORTS, Sep. 2015, Peer-reviewed

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• IFN-beta-inducing, unusual viral RNA species produced by paramyxovirus infection accumulated into distinct cytoplasmic structures in an RNA-type-dependent manner

  Asuka Yoshida; Ryoko Kawabata; Tomoyuki Honda; Keizo Tomonaga; Takemasa Sakaguchi; Takashi Irie

  FRONTIERS IN MICROBIOLOGY, Aug. 2015, Peer-reviewed

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• Borna disease virus possesses an NF-kappa B inhibitory sequence in the nucleoprotein gene

  Akiko Makino; Kan Fujino; Nicholas F. Parrish; Tomoyuki Honda; Keizo Tomonaga

  SCIENTIFIC REPORTS, Mar. 2015, Peer-reviewed

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• Taxonomic reorganization of the family Bornaviridae

  Jens H. Kuhn; Ralf Duerrwald; Yiming Bao; Thomas Briese; Kathryn Carbone; Anna N. Clawson; Joseph L. deRisi; Wolfgang Garten; Peter B. Jahrling; Jolanta Kolodziejek; Dennis Rubbenstroth; Martin Schwemmle; Mark Stenglein; Keizo Tomonaga; Herbert Weissenboeck; Norbert Nowotny

  ARCHIVES OF VIROLOGY, Feb. 2015, Peer-reviewed

  
• ボルナ病ウイルス感染症の病態研究

  本田 知之; 朝長 啓造

  化学療法の領域, 2015

  
• Heat stress is a potent stimulus for enhancing rescue efficiency of recombinant Borna disease virus

  Shohei Kojima; Tomoyuki Honda; Yusuke Matsumoto; Keizo Tomonaga

  MICROBIOLOGY AND IMMUNOLOGY, Nov. 2014, Peer-reviewed

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• Inhibition of Borna disease virus replication by an endogenous bornavirus-like element in the ground squirrel genome

  Kan Fujino; Masayuki Horie; Tomoyuki Honda; Dana K. Merriman; Keizo Tomonaga

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Sep. 2014, Peer-reviewed

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• Origin of an endogenous bornavirus-like nucleoprotein element in thirteen-lined ground squirrels

  Yoshiyuki Suzuki; Yuki Kobayashi; Masayuki Horie; Keizo Tomonaga

  GENES & GENETIC SYSTEMS, Jun. 2014, Peer-reviewed

  
• Comprehensive analysis of endogenous bornavirus-like elements in eukaryote genomes

  Masayuki Horie; Yuki Kobayashi; Yoshiyuki Suzuki; Keizo Tomonaga

  PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Sep. 2013, Peer-reviewed

  
• Molecular epidemiology of avian bornavirus from pet birds in Japan

  Yukiko Sassa; Masayuki Horie; Kan Fujino; Naomi Nishiura; Sachiko Okazaki; Tetsuya Furuya; Makoto Nagai; Tsutomu Omatsu; Atsushi Kojima; Masaya Mizugami; Kengo Ueda; Haruko Iki; Kazumasa Ebisawa; Keizo Tomonaga; Tetsuya Mizutani

  VIRUS GENES, Aug. 2013, Peer-reviewed

  
• Nucleocytoplasmic Shuttling of Viral Proteins in Borna Disease Virus Infection

  Tomoyuki Honda; Keizo Tomonaga

  VIRUSES-BASEL, Aug. 2013, Peer-reviewed

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• Host Molecular Chaperones: Cell Surface Receptors for Viruses.

  Honda T; Tomonaga K

  Heat Shock Proteins, 2013, Peer-reviewed

  
• Evolutionarily Conserved Interaction between the Phosphoproteins and X Proteins of Bornaviruses from Different Vertebrate Species

  Kan Fujino; Masayuki Horie; Tomoyuki Honda; Shoko Nakamura; Yusuke Matsumoto; Ivo M. B. Francischetti; Keizo Tomonaga

  PLOS ONE, Dec. 2012, Peer-reviewed

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• Generation of Human Bronchial Epithelial Cell Lines Expressing Inactive Mutants of GALNT3

  Shoko Nakamura; Masayuki Horie; Kan Fujino; Yusuke Matsumoto; Tomoyuki Honda; Keizo Tomonaga

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Nov. 2012, Peer-reviewed

  
• [Genome virology: the novel interaction of RNA viruses and host genomes].

  K. Tomonaga

  Uirusu, Jun. 2012, Peer-reviewed

  
• Bornavirus Closely Associates and Segregates with Host Chromosomes to Ensure Persistent Intranuclear Infection

  Yusuke Matsumoto; Yohei Hayashi; Hiroko Omori; Tomoyuki Honda; Takuji Daito; Masayuki Horie; Kazuyoshi Ikuta; Kan Fujino; Shoko Nakamura; Urs Schneider; Geoffrey Chase; Tamotsu Yoshimori; Martin Schwemmle; Keizo Tomonaga

  CELL HOST & MICROBE, May 2012, Peer-reviewed

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• Detection of Avian bornavirus 5 RNA in Eclectus roratus with feather picking disorder

  Masayuki Horie; Kengo Ueda; Akiko Ueda; Tomoyuki Honda; Keizo Tomonaga

  MICROBIOLOGY AND IMMUNOLOGY, May 2012, Peer-reviewed

  
• ボルナウイルス

  朝長啓造

  ウイルス62:209-218. 2012, 2012, Peer-reviewed

  
• ボルナウイルスをめぐる研究: 疫学から進化ウイルス学まで

  朝長啓造

  『化学療法の領域』 28:127-136. 2012, 2012, Peer-reviewed

  
• 鳥類のボルナウイルス感染症

  藤野寛; 朝長啓造

  エキゾチック診療.4:62-67. 2012, 2012, Peer-reviewed

  
• A Novel Borna Disease Virus Vector System That Stably Expresses Foreign Proteins from an Intercistronic Noncoding Region

  Takuji Daito; Kan Fujino; Tomoyuki Honda; Yusuke Matsumoto; Yohei Watanabe; Keizo Tomonaga

  JOURNAL OF VIROLOGY, Dec. 2011, Peer-reviewed

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• Non-Retroviral Fossils in Vertebrate Genomes

  Masayuki Horie; Keizo Tomonaga

  VIRUSES-BASEL, Oct. 2011, Peer-reviewed

  
• Analysis of Intracellular Distribution of Borna Disease Virus Glycoprotein Fused with Fluorescent Markers in Living Cells

  Takuji Daito; Kan Fujino; Yohei Watanabe; Kazuyoshi Ikuta; Keizo Tomonaga

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Sep. 2011, Peer-reviewed

  
• No Evidence for Natural Selection on Endogenous Borna-Like Nucleoprotein Elements after the Divergence of Old World and New World Monkeys

  Yuki Kobayashi; Masayuki Horie; Keizo Tomonaga; Yoshiyuki Suzuki

  PLOS ONE, Sep. 2011, Peer-reviewed

  
• Upregulation of Insulin-Like Growth Factor Binding Protein 3 in Astrocytes of Transgenic Mice That Express Borna Disease Virus Phosphoprotein

  Tomoyuki Honda; Kan Fujino; Daisuke Okuzaki; Naohiro Ohtaki; Yusuke Matsumoto; Masayuki Horie; Takuji Daito; Masayuki Itoh; Keizo Tomonaga

  JOURNAL OF VIROLOGY, May 2011, Peer-reviewed

  
• ボルナウイルスの基本性状

  松本祐介; 藤野寛; 朝長啓造

  臨床獣医.29:12-16. 2011, 2011, Peer-reviewed

  
• [Endogenous bornavirus elements in mammalian genome].

  M. Horie; K. Tomonaga

  Uirusu, Dec. 2010, Peer-reviewed

  
• Living fossil or evolving virus?

  Keizo Tomonaga

  EMBO REPORTS, May 2010, Peer-reviewed

  
• Endogenous non-retroviral RNA virus elements in mammalian genomes

  Masayuki Horie; Tomoyuki Honda; Yoshiyuki Suzuki; Yuki Kobayashi; Takuji Daito; Tatsuo Oshida; Kazuyoshi Ikuta; Patric Jern; Takashi Gojobori; John M. Coffin; Keizo Tomonaga

  NATURE, Jan. 2010, Peer-reviewed

  
• Molecular Chaperone BiP Interacts with Borna Disease Virus Glycoprotein at the Cell Surface

  Tomoyuki Honda; Masayuki Horie; Takuji Daito; Kazuyoshi Ikuta; Keizo Tomonaga

  JOURNAL OF VIROLOGY, Dec. 2009, Peer-reviewed

  
• Autogenous Translational Regulation of the Borna Disease Virus Negative Control Factor X from Polycistronic mRNA Using Host RNA Helicases

  Yohei Watanabe; Naohiro Ohtaki; Yohei Hayashi; Kazuyoshi Ikuta; Keizo Tomonaga

  PLOS PATHOGENS, Nov. 2009, Peer-reviewed

  
• Heat shock cognate protein 70 controls Borna disease virus replication via interaction with the viral non-structural protein X

  Yohei Hayashi; Masayuki Horie; Takuji Daito; Tomoyuki Honda; Kazuyoshi Ikuta; Keizo Tomonaga

  MICROBES AND INFECTION, Mar. 2009, Peer-reviewed

  
• Ribavirin inhibits Borna disease virus proliferation and fatal neurological diseases in neonatally infected gerbils

  Byeong-Jae Lee; Hidenori Matsunaga; Kazuyoshi Ikuta; Keizo Tomonaga

  ANTIVIRAL RESEARCH, Dec. 2008, Peer-reviewed

  
• Isotype analysis of human anti-Borna disease virus antibodies in Japanese psychiatric and general population

  Hidenori Matsunaga; Susumu Tanaka; Aldo Fukumori; Keizo Tomonaga; Kazuyoshi Ikuta; Nobuyuki Amino; Masatoshi Takeda

  JOURNAL OF CLINICAL VIROLOGY, Nov. 2008, Peer-reviewed

  
• Mechanism of nuclear transport and persistent infection of Borna disease virus

  K. Tomonaga

  Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Aug. 2007, Peer-reviewed

  
• Downregulation of an astrocyte-derived inflammatory protein, S100B, reduces vascular inflammatory responses in brains persistently infected with Borna disease virus

  Naohiro Ohtaki; Wataru Kamitani; Yohei Watanabe; Yohei Hayashi; Hideyuki Yanai; Kazuyoshi Ikuta; Keizo Tomonaga

  JOURNAL OF VIROLOGY, Jun. 2007, Peer-reviewed

  
• Characterization of a Borna disease virus field isolate which shows efficient viral propagation and transmissibility.

  Yohei Watanabe; Madiha S Ibrahim; Katsuro Hagiwara; Minoru Okamoto; Wataru Kamitani; Hideyuki Yanai; Naohiro Ohtaki; Yohei Hayashi; Hiroyuki Taniyama; Kazuyoshi Ikuta; Keizo Tomonaga

  Microbes and infection, Apr. 2007, Peer-reviewed

  
• Borna disease virus matrix protein is an integral component of the viral ribonucleoprotein complex that does not interfere with polymerase activity

  Geoffrey Chase; Daniel Mayer; Antonia Hildebrand; Ronald Frank; Yohei Hayashi; Keizo Tomonaga; Martin Schwemmle

  JOURNAL OF VIROLOGY, Jan. 2007, Peer-reviewed

  
• Establishment of a reverse genetics system for rotavirus: a multisegmented double-stranded RNA virus

  Keizo Tomonaga; Kazuyoshi Ikuta

  FUTURE VIROLOGY, Sep. 2006, Peer-reviewed

  
• Mixed Infection with Cryptococcus (Neoformans) and Borna Disease Virus in a Cat

  TAMURA Shinji; TAMURA Yumiko; SUZUOKA Nobutaka; OHOKA Aya; HASEGAWA Takahisa; UCHIDA Kazuyuki; WATANABE Yohei; TOMONAGA Keizo

  動物臨床医学 = Journal of Animal Clinical Research Foundation, 20 Jun. 2006

  
• Development of a novel Borna disease virus reverse genetics system using RNA polymerase II promoter and SV40 nuclear import signal

  Hideyuki Yanai; Yohei Hayashi; Yohei Watanabe; Naohiro Ohtaki; Takeshi Kobayashi; Yasutoshi Nozaki; Kazuyoshi Ikuta; Keizo Tomonaga

  MICROBES AND INFECTION, May 2006, Peer-reviewed

  
• Prevalence of Borna disease virus antibodies in healthy Japanese black cattle in Kyushu

  Y Watanabe; H Yanai; N Ohtaki; K Ikuta; K Tomonaga

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Feb. 2006, Peer-reviewed

  
• A methionine-rich domain mediates CRM1-dependent nuclear export activity of Borna disease virus phosphoprotein

  H Yanai; T Kobayashi; Y Hayashi; Y Watanabe; N Ohtaki; GQ Zhang; JC de la Torre; K Ikuta; K Tomonaga

  JOURNAL OF VIROLOGY, Feb. 2006, Peer-reviewed

  
• 脳内にクリプトコッカスとボルナ病ウイルスが重複感染した猫の1例

  田村 慎司; 田村 由美子; 鈴岡 宣孝; 大岡 恵; 長谷川 孝寿; 内田 和幸; 渡邊 洋平; 朝長 啓造

  動物臨床医学会年次大会プロシーディング, Nov. 2005

  
• A Cat with Borna Disease Virus Infection

  TSURUOKA Hiroshi; WATANABE Yohei; TOMONAGA Keizo

  動物臨床医学 = Journal of Animal Clinical Research Foundation, 20 Sep. 2005

  
• RAGE機能阻害によるウイルス性脳炎の抑制

  大滝 尚広; 神谷 亘; 渡邊 洋平; 矢内 英之; 林 陽平; 生田 和良; 朝長 啓造

  日本獣医学会学術集会講演要旨集, Aug. 2005

  
• RNA polymerase IIプロモーターを用いたBDVミニゲノムの構築とリバース・ジェネティクスへの応用

  矢内 英之; 渡邊 洋平; 大滝 尚広; 林 陽平; 生田 和良; 朝長 啓造

  日本獣医学会学術集会講演要旨集, Aug. 2005

  
• ウシ由来BDV野外分離株の性状解析

  渡邊 洋平; 神谷 亘; 大滝 尚広; 矢内 英之; 林 陽平; 萩原 克郎; 岡本 実; 谷山 弘行; 生田 和良; 朝長 啓造

  日本獣医学会学術集会講演要旨集, Aug. 2005

  
• Enzootic intranasal tumour virus infection in apparently healthy sheep in Japan

  K Kawasako; M Okamoto; T Kurosawa; T Nakade; R Kirisawa; T Miyashou; M Komine; T Go; S Imazu; N Takeuchi; K Tomonaga; K Ikuta; Y Akihara; Y Shimoyama; K Hirayama; H Taniyama

  VETERINARY RECORD, Jul. 2005, Peer-reviewed

  
• Detection by radioligand assay of antibodies against Borna disease virus in patients with various psychiatric disorders

  H Matsunaga; S Tanaka; F Sasao; Y Nishino; M Takeda; K Tomonaga; K Ikuta; N Amino

  CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, May 2005, Peer-reviewed

  
• Prevention of PERV infections in pig to human xenotransplantation by the RNA interference silences gene

  S Miyagawa; S Nakatsu; T Nakagawa; A Kondo; K Matsunami; K Hazama; J Yamada; K Tomonaga; T Miyazawa; R Shirakura

  JOURNAL OF BIOCHEMISTRY, Apr. 2005, Peer-reviewed

  
• Persistent Borna disease virus infection confers instability of HSP70 mRNA in glial cells during heat stress

  M Yamashita; W Kamitani; H Yanai; N Ohtaki; Y Watanabe; BJ Lee; S Tsuji; K Ikuta; K Tomonaga

  JOURNAL OF VIROLOGY, Feb. 2005, Peer-reviewed

  
• The effect of complement regulatory protein expression on pig endothelial cells to porcine endogenous retrovirus lyses by human sera

  K Hazama; S Miyagawa; A Yamamoto; T Kubo; T Miyazawa; K Tomonaga; R Watanabe; M Okumura; H Matsuda; R Shirakura

  TRANSPLANTATION PROCEEDINGS, Jan. 2005, Peer-reviewed

  
• BDV感染による糖化最終産物レセプター(RAGE)の発現動態の解析

  大滝 尚広; 神谷 亘; 李 丙載; 渡邊 洋平; 山下 真紀子; 矢内 英之; 生田 和良; 朝長 啓造

  日本獣医学会学術集会講演要旨集, Mar. 2004

  
• BDV持続感染細胞にみられる核内ドット状構造物の動態とゲノム複製への役割

  矢内 英之; 神谷 亘; 李 丙載; 張 国旗; 山下 真紀子; 渡邊 洋平; 大滝 尚広; 生田 和良; 朝長 啓造

  日本獣医学会学術集会講演要旨集, Mar. 2004

  
• ボルナ病ウイルス持続感染機序の解析

  朝長 啓造; 矢内 英之; 神谷 亘; 渡邊 洋平; 大滝 尚広; 李 丙載; 山下 真紀子; 生田 和良

  日本獣医学会学術集会講演要旨集, Mar. 2004

  
• ウシにおけるボルナ病ウイルス疫学調査と野外分離株の性状解析

  渡邊 洋平; 神谷 亘; 李 丙載; 山下 真紀子; 大滝 尚広; 矢内 英之; 笹尾 芙蓉子; 岡本 実; 谷山 弘行; 荻原 克郎; 生田 和良; 朝長 啓造

  日本獣医学会学術集会講演要旨集, Mar. 2004

  
• Virus-induced neurobehavioral disorders: mechanisms and implications

  K Tomonaga

  TRENDS IN MOLECULAR MEDICINE, Feb. 2004, Peer-reviewed

  
• Experimental transmission of abnormal prion protein (PrPsc) in the small intestinal epithelial cells of neonatal mice

  M Okamoto; H Furuoka; M Horiuchi; T Noguchi; K Hagiwara; Y Muramatsu; K Tomonaga; M Tsuji; C Ishihara; K Ikuta; H Taniyama

  VETERINARY PATHOLOGY, Nov. 2003, Peer-reviewed

  
• Age- and host-dependent control of Borna disease virus spread in the developing brains of gerbils and rats

  BJ Lee; M Watanabe; W Kamitani; S Baba; M Yamashita; T Kobayashi; K Tomonaga; K Ikuta

  MICROBES AND INFECTION, Nov. 2003, Peer-reviewed

  
• Borna disease virus phosphoprotein represses p53-mediated transcriptional activity by interference with HMGB1

  GQ Zhang; T Kobayashi; W Kamitani; S Komoto; M Yamashita; S Baba; H Yanai; K Ikuta; K Tomonaga

  JOURNAL OF VIROLOGY, Nov. 2003, Peer-reviewed

  
• Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes

  T Kurihara; T Miyazawa; S Miyagawa; K Tomonaga; K Hazama; J Yamada; R Shirakura; Y Matsuura

  XENOTRANSPLANTATION, Nov. 2003, Peer-reviewed

  
• The significance of N-linked glycosylation in pig endogenous retrovirus infectivity

  K Hazama; S Miyagawa; T Miyazawa; J Yamada; K Tomonaga; M Ota; H Matsuda; R Shirakura

  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Oct. 2003, Peer-reviewed

  
• Experimental vertical transmission of Borna disease virus in the mouse

  M Okamoto; K Hagiwara; W Kamitani; T Sako; K Hirayama; R Kirisawa; M Tsuji; C Ishihara; H Iwai; T Kobayashi; K Tomonaga; K Ikuta; H Taniyama

  ARCHIVES OF VIROLOGY, Aug. 2003, Peer-reviewed

  
• Glial expression of Borna disease virus phosphoprotein induces behavioral and neurological abnormalities in transgenic mice

  W Kamitani; E Ono; S Yoshino; T Kobayashi; S Taharaguchi; BJ Lee; M Yamashita; T Kobayashi; M Okamoto; H Taniyama; K Tomonaga; K Ikuta

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jul. 2003, Peer-reviewed

  
• Modulation of Borna disease virus phosphoprotein nuclear localization by the viral protein X encoded in the overlapping open reading frame

  T Kobayashi; GQ Zhang; BJ Lee; S Baba; M Yamashita; W Kamitani; H Yanai; K Tomonaga; K Ikuta

  JOURNAL OF VIROLOGY, Jul. 2003, Peer-reviewed

  
• The mechanism of persistent infection and pathogenesis of Borna disease virus

  K. Tomonaga

  Uirusu. Journal of virology, Jun. 2003, Peer-reviewed

  
• Borna disease virus induces acute fatal neurological disorders in neonatal gerbils without virus- and immune-mediated cell destructions

  M Watanabe; BJ Lee; M Yamashita; W Kamitani; T Kobayashi; K Tomonaga; K Ikuta

  VIROLOGY, Jun. 2003, Peer-reviewed

  
• [Borna disease virus infection].

  Kamitani W; Tomonaga K; Ikuta K

  Nihon rinsho. Japanese journal of clinical medicine, Feb. 2003, Peer-reviewed

  
• Borna disease virus: its broad host range and neuropathogenesis

  K. Tomonaga

  Virus, Jun. 2002, Peer-reviewed

  
• Molecular and cellular biology of Borna disease virus infection

  K Tomonaga; T Kobayashi; K Ikuta

  MICROBES AND INFECTION, Apr. 2002, Peer-reviewed

  
• Varied persistent life cycles of Borna disease virus in a human oligodendroglioma cell line

  MS Ibrahim; M Watanabe; JA Palacios; W Kamitani; S Komoto; T Kobayashi; K Tomonaga; K Ikuta

  JOURNAL OF VIROLOGY, Apr. 2002, Peer-reviewed

  
• Borna disease virus and infection in humans

  K Ikuta; MS Ibrahim; T Kobayashi; K Tomonaga

  FRONTIERS IN BIOSCIENCE-LANDMARK, Feb. 2002, Peer-reviewed

  
• Borna disease virus phosphoprotein binds a neurite outgrowth factor, amphoterin/HMG-1

  W Kamitani; Y Shoya; T Kobayashi; M Watanabe; BJ Lee; GQ Zhang; K Tomonaga; K Ikuta

  JOURNAL OF VIROLOGY, Sep. 2001, Peer-reviewed

  
• The neuropathogenesis of Borna disease virus infection

  K. Tomonaga; T. Kobayashi; K. Ikuta

  Nippon rinsho. Japanese journal of clinical medicine, Aug. 2001, Peer-reviewed

  
• Borna disease virus nucleoprotein requires both nuclear localization and export activities for viral nucleocytoplasmic shuttling

  T Kobayashi; W Kamitani; GQ Zhang; M Watanabe; K Tomonaga; K Ikuta

  JOURNAL OF VIROLOGY, Apr. 2001, Peer-reviewed

  
• Neurological diseases and viral dynamics in the brains of neonatally borna disease virus-infected gerbils

  M Watanabe; BJ Lee; W Kamitani; T Kobayashi; H Taniyama; K Tomonaga; K Ikuta

  VIROLOGY, Mar. 2001, Peer-reviewed

  
• Identification of alternative splicing and negative splicing activity of a nonsegmented negative-strand RNA virus, Borna disease virus

  K Tomonaga; T Kobayashi; BJ Lee; M Watanabe; W Kamitani; K Ikuta

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Nov. 2000, Peer-reviewed

  
• Translation initiation of a bicistronic mRNA of borna disease virus: A 16-kDa phosphoprotein is initiated at an internal start codon

  T Kobayashi; M Watanabe; W Kamitani; K Tomonaga; K Ikuta

  VIROLOGY, Nov. 2000, Peer-reviewed

  
• Antibodies to Borna disease virus in infected adult rats: An early appearance of anti-p10 antibody and recognition of novel virus-specific proteins in infected animal brain cells

  M Watanabe; T Kobayashi; K Tomonaga; K Ikuta

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Jul. 2000, Peer-reviewed

  
• Isolation of Borna disease virus from human brain tissue

  Y Nakamura; H Takahashi; Y Shoya; T Nakaya; M Watanabe; K Tomonaga; K Iwahashi; K Ameno; N Momiyama; H Taniyama; T Sata; T Kurata; JC De la Torre; K Ikuta

  JOURNAL OF VIROLOGY, May 2000, Peer-reviewed

  
• Molecular ratio between borna disease viral-p40 and-p24 proteins in infected cells determined by quantitative antigen capture ELISA

  M Watanabe; Q Zhong; T Kobayashi; W Kamitani; K Tomonaga; K Ikuta

  MICROBIOLOGY AND IMMUNOLOGY, 2000, Peer-reviewed

  
• Structures of endogenous nonecotropic murine leukemia virus (MLV) long terminal repeats in wild mice: Implication for evolution of MLVs

  K Tomonaga; JM Coffin

  JOURNAL OF VIROLOGY, May 1999, Peer-reviewed

  
• Epitopes and nuclear localization analyses of canine distemper virus nucleocapsid protein by expression of its deletion mutants

  E Yoshida; YS Shin; K Iwatsuki; T Gemma; N Miyashita; K Tomonaga; N Hirayama; T Mikami; C Kai

  VETERINARY MICROBIOLOGY, May 1999, Peer-reviewed

  
• Structure and distribution of endogenous nonecotropic murine leukemia viruses in wild mice

  K Tomonaga; JM Coffin

  JOURNAL OF VIROLOGY, Oct. 1998, Peer-reviewed

  
• Characterization of an integrase mutant of feline immunodeficiency virus

  K Tomonaga; SI Itagaki; H Kashiwase; Y Kawaguchi; Y Inoshima; Y Ikeda; T Mikami

  ARCHIVES OF VIROLOGY, 1998, Peer-reviewed

  
• Replication of feline syncytial virus in feline T-lymphoblastoid cells and induction of apoptosis in the cells

  Y Ikeda; SI Itagaki; S Tsutsui; Y Inoshima; M Fukasawa; K Tomonaga; Y Tohya; K Maeda; M Mochizuki; T Miyazawa; T Mikami

  MICROBIOLOGY AND IMMUNOLOGY, 1997, Peer-reviewed

  
• Expression of the nucleocapsid protein gene of the canine distemper virus

  YS Shin; T Mori; K Tomonaga; K Iwatsuki; C Kai; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Jan. 1997, Peer-reviewed

  
• Roles of the auxiliary genes and AP-1 binding site in the long terminal repeat of feline immunodeficiency virus in the early stage of infection in cats

  Y Inoshima; M Kohmoto; Y Ikeda; H Yamada; Y Kawaguchi; K Tomonaga; T Miyazawa; C Kai; T Umemura; T Mikami

  JOURNAL OF VIROLOGY, Dec. 1996, Peer-reviewed

  
• Persistence of high virus neutralizing antibody titers in cats experimentally infected with feline immunodeficiency virus

  Y Inoshima; Y Ikeda; M Kohmoto; MR Pecoraro; M Shimojima; Y Shimojima; G Inada; Y Kawaguchi; K Tomonaga; T Miyazawa; T Mikami

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Sep. 1996, Peer-reviewed

  
• Genetic diversity of Argentine isolates of feline immunodeficiency virus

  MR Pecoraro; K Tomonaga; T Miyazawa; Y Kawaguchi; S Sugita; Y Tohya; C Kai; ME Etcheverrigaray; T Mikami

  JOURNAL OF GENERAL VIROLOGY, Sep. 1996, Peer-reviewed

  
• Feline immunodeficiency virus can infect a human cell line (MOLT-4) but establishes a state of latency in the cells

  Y Ikeda; K Tomonaga; Y Kawaguchi; M Kohmoto; Y Inoshima; Y Tohya; T Miyazawa; C Kai; T Mikami

  JOURNAL OF GENERAL VIROLOGY, Aug. 1996, Peer-reviewed

  
• Molecular biology of the feline immunodeficiency virus auxiliary genes

  K Tomonaga; T Mikami

  JOURNAL OF GENERAL VIROLOGY, Aug. 1996, Peer-reviewed

  
• Regulatory properties of the integrated long terminal repeat of the feline immunodeficiency virus

  Y Ikeda; Y Kawaguchi; K Tomonaga; Y Inoshima; M Kohmoto; T Miyazawa; T Mikami

  VIRUS RESEARCH, Apr. 1996, Peer-reviewed

  
• Detection of feline immunodeficiency virus transcripts by quantitative reverse transcription-polymerase chain reaction

  K Tomonaga; T Mikami

  VETERINARY MICROBIOLOGY, Feb. 1996, Peer-reviewed

  
• TEMPORAL PATTERNS OF FELINE IMMUNODEFICIENCY VIRUS TRANSCRIPTS IN PERIPHERAL-BLOOD CELLS DURING THE LATENT STAGE OF INFECTION

  K TOMONAGA; Y INOSHIMA; Y IKEDA; T MIKAMI

  JOURNAL OF GENERAL VIROLOGY, Sep. 1995, Peer-reviewed

  
• QUANTIFICATION OF FELINE IMMUNODEFICIENCY VIRUS (FIV) PROVIRAL DNA IN PERIPHERAL-BLOOD MONONUCLEAR-CELLS OF CATS INFECTED WITH JAPANESE STRAINS OF FIV

  Y INOSHIMA; K TOMONAGA; Y IKEDA; T MIYAZAWA; T MIKAMI

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Jun. 1995, Peer-reviewed

  
• THE C/EBP SITE IN THE FELINE IMMUNODEFICIENCY VIRUS (FIV) LONG TERMINAL REPEAT (LTR) IS NECESSARY FOR ITS EFFICIENT REPLICATION AND IS ALSO INVOLVED IN THE INHIBITION OF FIV LTR-DIRECTED GENE-EXPRESSION BY PSEUDORABIES VIRUS ICP4

  Y KAWAGUCHI; K TOMONAGA; K MAEDA; M ONO; T MIYAZAWA; M KOHMOTO; Y TOHYA; T MIKAMI

  VIROLOGY, Apr. 1995, Peer-reviewed

  
• SEROEPIDEMIOLOGICAL SURVEY OF FELINE RETROVIRUS INFECTIONS IN CATS IN TAIWAN IN 1993 AND 1994

  JA LIN; MC CHENG; Y INOSHIMA; K TOMONAGA; T MIYAZAWA; Y TOHYA; K TOH; YS LU; T MIKAMI

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Feb. 1995, Peer-reviewed

  
• ESTABLISHMENT OF CARRIER-STATE INFECTION OF A FELINE RENAL-CELL LINE WITH FELINE SYNCYTIAL VIRUS

  T MIYAZAWA; S ITAGAKI; K TOMONAGA; Y IKEDA; T MORI; Y KAWAGUCHI; T GEMMA; Y TOHYA; M MOCHIZUKI; T MIKAMI

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Feb. 1995, Peer-reviewed

  
• PHYLOGENETIC ANALYSIS OF THE LONG TERMINAL REPEAT OF FELINE IMMUNODEFICIENCY VIRUSES FROM JAPAN, ARGENTINA AND AUSTRALIA

  H YAMADA; T MIYAZAWA; K TOMONAGA; Y KAWAGUCHI; K MAEDA; MC CASTELLANO; C KAI; Y TOHYA; T MIKAMI

  ARCHIVES OF VIROLOGY, 1995, Peer-reviewed

  
• THE MOLECULAR-CLONING AND SEQUENCE OF AN OPEN READING FRAME ENCODING FOR NONSTRUCTURAL PROTEINS OF FELINE CALICIVIRUS F4 STRAIN ISOLATED IN JAPAN

  R OSHIKAMO; Y TOHYA; Y KAWAGUCHI; K TOMONAGA; K MAEDA; N TAKEDA; E UTAGAWA; C KAI; T MIKAMI

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Dec. 1994, Peer-reviewed

  
• COMPARATIVE FUNCTIONAL-ANALYSIS OF THE VARIOUS LENTIVIRUS LONG TERMINAL REPEATS IN HUMAN COLON-CARCINOMA CELL-LINE (SW480 CELLS) AND FELINE RENAL-CELL LINE (CRFK CELLS)

  T MIYAZAWA; Y KAWAGUCHI; M KOHMOTO; K TOMONAGA; T MIKAMI

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Oct. 1994, Peer-reviewed

  
• INHIBITION OF FELINE IMMUNODEFICIENCY VIRUS GENE-EXPRESSION AND REPLICATION BY ALPHAHERPESVIRUS ICP4 HOMOLOGS

  Y KAWAGUCHI; K MAEDA; T MIYAZAWA; M ONO; K TSUBOTA; K TOMONAGA; T MIKAMI

  JOURNAL OF GENERAL VIROLOGY, Oct. 1994, Peer-reviewed

  
• COMPARISON OF BIOLOGICAL PROPERTIES OF FELINE IMMUNODEFICIENCY VIRUS ISOLATES USING RECOMBINANT CHIMERIC VIRUSES

  M KOHMOTO; T MIYAZAWA; K TOMONAGA; Y KAWAGUCHI; T MORI; YB TOHYA; C KAI; T MIKAMI

  JOURNAL OF GENERAL VIROLOGY, Aug. 1994, Peer-reviewed

  
• COMPARISON OF THE REV TRANSACTIVATION OF FELINE IMMUNODEFICIENCY VIRUS IN FELINE AND NON-FELINE CELL-LINES

  K TOMONAGA; T MIYAZAWA; Y KAWAGUCHI; M KOHMOTO; Y INOSHIMA; T MIKAMI

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Feb. 1994, Peer-reviewed

  
• EFFECTS OF INSERTION OF MULTIPLE AP-1 BINDING SITES INTO THE U3 REGION OF THE LONG TERMINAL REPEAT OF FELINE IMMUNODEFICIENCY VIRUS

  T MIYAZAWA; K TOMONAGA; Y KAWAGUCHI; M KOHMOTO; Y INOSHIMA; K MAEDADEL; T MIKAMI

  ARCHIVES OF VIROLOGY, 1994, Peer-reviewed

  
• THE GENOME OF FELINE IMMUNODEFICIENCY VIRUS

  T MIYAZAWA; K TOMONAGA; Y KAWAGUCHI; T MIKAMI

  ARCHIVES OF VIROLOGY, 1994, Peer-reviewed

  
• FELINE IMMUNODEFICIENCY VIRUS GENE-EXPRESSION - ANALYSIS OF THE RNA SPLICING PATTERN AND THE MONOCISTRONIC REV MESSENGER-RNA

  K TOMONAGA; YS SHIN; M FUKASAWA; T MIYAZAWA; A ADACHI; T MIKAMI

  JOURNAL OF GENERAL VIROLOGY, Nov. 1993, Peer-reviewed

  
• ANTIGENIC ANALYSIS OF FELINE CALCIVIRUS CAPSID PRECURSOR PROTEIN AND ITS DELETED POLYPEPTIDES PRODUCED IN A MAMMALIAN CDNA EXPRESSION SYSTEM

  YS SHIN; Y TOHYA; R OSHIKAMO; Y KAWAGUCHI; K TOMONAGA; T MIYAZAWA; C KAI; T MIKAMI

  VIRUS RESEARCH, Oct. 1993, Peer-reviewed

  
• THE FELINE IMMUNODEFICIENCY VIRUS ORF-A GENE FACILITATES EFFICIENT VIRAL REPLICATION IN ESTABLISHED T-CELL LINES AND PERIPHERAL-BLOOD LYMPHOCYTES

  K TOMONAGA; T MIYAZAWA; J SAKURAGI; T MORI; A ADACHI; T MIKAMI

  JOURNAL OF VIROLOGY, Oct. 1993, Peer-reviewed

  
• THE AP-1 BINDING-SITE IN THE FELINE IMMUNODEFICIENCY VIRUS LONG TERMINAL REPEAT IS NOT REQUIRED FOR VIRUS-REPLICATION IN FELINE T-LYMPHOCYTES

  T MIYAZAWA; M KOHMOTO; Y KAWAGUCHI; K TOMONAGA; T TOYOSAKI; K IKUTA; A ADACHI; T MIKAMI

  JOURNAL OF GENERAL VIROLOGY, Aug. 1993, Peer-reviewed

  
• ISOLATION AND CHARACTERIZATION OF SIMIAN IMMUNODEFICIENCY VIRUS FROM AFRICAN WHITE-CROWNED MANGABEY MONKEYS (CERCOCEBUS-TORQUATUS-LUNULATUS)

  K TOMONAGA; J KATAHIRA; M FUKASAWA; MA HASSAN; M KAWAMURA; H AKARI; T MIURA; T GOTO; M NAKAI; M SULEMAN; M ISAHAKIA; M HAYAMI

  ARCHIVES OF VIROLOGY, 1993, Peer-reviewed

  
• LOCALIZATION OF THE VIRAL-ANTIGEN OF FELINE IMMUNODEFICIENCY VIRUS IN THE LYMPH-NODES OF CATS AT THE EARLY-STAGE OF INFECTION

  T TOYOSAKI; T MIYAZAWA; T FURUYA; K TOMONAGA; YS SHIN; M OKITA; Y KAWAGUCHI; C KAI; S MORI; T MIKAMI

  ARCHIVES OF VIROLOGY, 1993, Peer-reviewed

  
• FELINE CD4 MOLECULES EXPRESSED ON FELINE NONLYMPHOID CELL-LINES ARE NOT ENOUGH FOR PRODUCTIVE INFECTION OF HIGHLY LYMPHOTROPIC FELINE IMMUNODEFICIENCY VIRUS ISOLATES

  J NORIMINE; T MIYAZAWA; Y KAWAGUCHI; K TOMONAGA; YS SHIN; T TOYOSAKI; M KOHMOTO; M NIIKURA; Y TOHYA; T MIKAMI

  ARCHIVES OF VIROLOGY, 1993, Peer-reviewed

  
• IDENTIFICATION OF A FELINE IMMUNODEFICIENCY VIRUS GENE WHICH IS ESSENTIAL FOR CELL-FREE VIRUS INFECTIVITY

  K TOMONAGA; J NORIMINE; YS SHIN; M FUKASAWA; T MIYAZAWA; A ADACHI; T TOYOSAKI; Y KAWAGUCHI; C KAI; T MIKAMI

  JOURNAL OF VIROLOGY, Oct. 1992, Peer-reviewed

  
• ISOLATION AND CHARACTERIZATION OF A HIGHLY DIVERGENT HIV-2[GH-2] - GENERATION OF AN INFECTIOUS MOLECULAR CLONE AND FUNCTIONAL-ANALYSIS OF ITS REV-RESPONSIVE ELEMENT IN RESPONSE TO PRIMATE RETROVIRUS TRANSACTIVATORS (REV AND REX)

  M KAWAMURA; J KATAHIRA; M FUKASAWA; JI SAKURAGI; KI ISHIKAWA; M NAKAI; JAA MINGLE; M OSEIKWASI; VBA NETTY; H AKARI; O HISHIDA; K TOMONAGA; T MIURA; M HAYAMI

  VIROLOGY, Jun. 1992, Peer-reviewed

  
• FURTHER CHARACTERIZATION OF A FELINE T-LYMPHOBLASTOID CELL-LINE (MYA-1 CELLS) HIGHLY SENSITIVE FOR FELINE IMMUNODEFICIENCY VIRUS

  T MIYAZAWA; T TOYOSAKI; K TOMONAGA; J NORIMINE; K OHNO; A HASEGAWA; C KAI; T MIKAMI

  JOURNAL OF VETERINARY MEDICAL SCIENCE, Feb. 1992, Peer-reviewed

  
• IDENTIFICATION AND NUCLEOTIDE-SEQUENCE OF A GENE IN FELINE HERPESVIRUS TYPE-1 HOMOLOGOUS TO THE HERPES-SIMPLEX VIRUS GENE ENCODING THE GLYCOPROTEIN-B

  K MAEDA; T HORIMOTO; J NORIMINE; Y KAWAGUCHI; K TOMONAGA; M NIIKURA; C KAI; E TAKAHASHI; T MIKAMI

  ARCHIVES OF VIROLOGY, 1992, Peer-reviewed

  
• BIOLOGICAL CHARACTERIZATION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 AND TYPE-2 MUTANTS IN HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS

  H AKARI; J SAKURAGI; Y TAKEBE; K TOMONAGA; M KAWAMURA; M FUKASAWA; T MIURA; T SHINJO; M HAYAMI

  ARCHIVES OF VIROLOGY, 1992, Peer-reviewed

  

Misc.

• Identification of the fusion loop of Borna disease virus G protein

  秋葉優沙; 秋葉優沙; 松郷宙倫; 松郷宙倫; 朝長啓造; 朝長啓造; 朝長啓造

  日本ウイルス学会学術集会プログラム・予稿集(Web), 2024

  
• Genome-wide CRISPR screening for host factors involved in bornavirus cell entry

  松郷宙倫; 松郷宙倫; 遊佐宏介; 牧野晶子; 牧野晶子; 朝長啓造; 朝長啓造; 朝長啓造

  日本ウイルス学会学術集会プログラム・予稿集(Web), 2024

  
• トリボルナウイルス自然感染鳥における皮膚病変とウイルス局在の解析

  芳野素一; 相原尚之; 志賀崇徳; 曽我玲子; 牧野晶子; 朝長啓造; 上家潤一

  日本獣医学会学術集会講演要旨集, 2022

  
• Identification and characterization of novel deltaviruses revealed the diversity of strategy for deltavirus transmission

  岩本将士; 岩本将士; 柴田ゆき野; 川崎純菜; 小嶋将平; LI Yung-Tsung; 岩見真吾; 村松正道; WU Hui-Lin; 和多和宏; 朝長啓造; 渡士幸一; 堀江真行

  日本ウイルス学会学術集会プログラム・予稿集(Web), 2021

  
• ゲノムワイドCRISPRスクリーニングによるボルナウイルスの転写・複製・持続感染に関わる宿主因子の探索

  松郷宙倫; 遊佐宏介; 牧野晶子; 朝長啓造; 松郷宙倫; 牧野晶子; 朝長啓造; 朝長啓造

  日本獣医学会学術集会講演要旨集, 2023

  
• ボルナ病ウイルス核タンパク質-RNA複合体形成の構造基盤

  後藤真也; 後藤真也; 平井悠哉; 朝長啓造; 野田岳志; 野田岳志; 堀江真行; 堀江真行; 杉田征彦; 杉田征彦; 杉田征彦

  日本蛋白質科学会年会プログラム・要旨集, 2023

  
• Structural insights into the Borna disease virus 1 nucleoprotein-RNA complex assembly

  後藤真也; 後藤真也; 平井悠哉; 朝長啓造; 朝長啓造; 朝長啓造; 野田岳志; 野田岳志; 堀江真行; 堀江真行; 杉田征彦; 杉田征彦; 杉田征彦

  日本ウイルス学会学術集会プログラム・予稿集(Web), 2023

  
• Three-dimensional structures of the Borna disease virus 1 nucleoprotein-RNA complex

  杉田征彦; 杉田征彦; 杉田征彦; 平井悠哉; 後藤真也; 後藤真也; 朝長啓造; 朝長啓造; 朝長啓造; 野田岳志; 野田岳志; 堀江真行; 堀江真行

  日本ウイルス学会学術集会プログラム・予稿集(Web), 2023

  
• 複製効率の異なるBDV株間における病原性および感染性粒子形成能の比較

  渡邊洋平; 神谷亘; 李丙載; 山下真紀子; 矢内英之; 大滝尚広; 笹尾芙蓉子; 岡本実; 谷山弘行; 萩原克郎; 朝長啓造; 生田和良

  日本ウイルス学会学術集会プログラム・抄録集, 2004

  
• BDVの複製と持続感染を制御するpolycistronic mRNAの新規翻訳調節機構の解明

  渡邊洋平; 林陽平; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2008

  
• ボルナ病ウイルスP遺伝子トランスジェニックマウスにおけるグリア機能異常の解析

  本田知之; 大滝尚広; 渡邊洋平; 林陽平; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2007

  
• 特定疾患の微生物学的原因究明に関する研究 2.神経変性疾患とボルナ病ウイルス感染との関連性に関する研究

  生田和良; 朝長啓造; 渡邊洋平; 大滝尚広; 林陽平

  特定疾患の微生物学的原因究明に関する研究 平成18年度 総括・分担研究報告書, 2007

  
• BDV vRNPのクロマチンターゲティング機構の解析

  林陽平; 堀江真行; 矢内英之; 渡邊洋平; 大滝尚広; 本田知之; 大東卓史; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2007

  
• 宿主因子による5′非翻訳領域の二次構造変化を介したBDV polycistronic mRNAの翻訳制御機構

  渡邊洋平; 林陽平; 本田知之; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2007

  
• 特定疾患の微生物学的原因究明に関する研究 2. 神経変性疾患とボルナ病ウイルス感染との関連性に関する研究

  生田和良; 朝長啓造; 渡邊洋平; 大滝尚広; 林陽平

  特定疾患の微生物学的原因究明に関する研究 平成17年度 総括・分担研究報告書, 2006

  
• BDV polycistronic mRNAの翻訳制御に関与する核内因子群の同定

  渡邊洋平; 林陽平; 大滝尚広; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2006

  
• クロマチン環境に依存したボルナ病ウイルスの転写調節機構の解析

  林陽平; 矢内英之; 渡邊洋平; 大滝尚広; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2006

  
• ボルナ病ウイルス持続感染によるS100Bの発現低下とアストロサイト機能への影響

  大滝尚広; 渡邊洋平; 林陽平; 神谷亘; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2006

  
• RNA polymerase IIプロモーターを用いたBDVミニゲノムの構築とVLP作製の試み

  矢内英之; 渡邊洋平; 大滝尚広; 林陽平; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2005

  
• BDV vRNPの核内維持と複製に関わるクロマチン結合タンパク質の役割

  朝長啓造; 矢内英之; 林陽平; 大滝尚広; 渡邊洋平; 生田和良

  日本ウイルス学会学術集会プログラム・抄録集, 2005

  
• 持続感染を生み出す脳内機構:ボルナ病ウイルスによるRAGE発現抑制と脳炎制御機構の解明

  大滝尚広; 渡邊洋平; 矢内英之; 林陽平; 神谷亘; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2005

  
• ボルナ病ウイルスX/P polycistronic mRNAの翻訳調節機構の解析

  渡邊洋平; 矢内英之; 大滝尚広; 林陽平; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2005

  
• ウイルス持続感染における脳内RAGE発現の意義

  大滝尚広; 渡邊洋平; 矢内英之; 神谷亘; 李丙載; 山下真紀子; 笹尾芙蓉子; 朝長啓造; 生田和良

  日本ウイルス学会学術集会プログラム・抄録集, 2004

  
• BDV vRNPの分裂期クロマチンへの局在と持続感染への意義

  朝長啓造; 矢内英之; 神谷亘; 李丙載; 大滝尚広; 渡邊洋平; 生田和良

  日本ウイルス学会学術集会プログラム・抄録集, 2004

  
• BDV感染細胞に見られる核内ドット状構造物の動態と存在意義の解析

  矢内英之; 渡邊洋平; 大滝尚弘; 神谷亘; 山下真紀子; 笹尾芙蓉子; 朝長啓造; 生田和良

  日本ウイルス学会学術集会プログラム・抄録集, 2004

  
• 京都大学ウイルス研究所ヒトがんウイルス研究分野

  朝長 啓造

  ウイルス, 01 Dec. 2011

  
• PS-003-5 α-Mannosidase I遺伝子導入によるブタ内在性レトロウイルスのヒト細胞への感染制御の試み

  狭間 研至; 宮川 周士; 宮沢 孝幸; 山田 順子; 朝長 啓造; 太田 三徳; 松田 暉; 白倉 良太

  日本外科学会雑誌, 15 Mar. 2004

  
• ボルナ病ウイルス感染症 (特集 人獣共通感染症) -- (2.プリオン病とウイルス性人獣共通感染症)

  朝長 啓造

  畜産の研究, Jan. 2004

  
• ボルナ病ウイルス:中枢神経疾患発症の機序 (特集 新興・再興感染症) -- (新興感染症)

  朝長 啓造

  モレキュラ-メディシン, Aug. 2003

  
• オウム目におけるトリボルナウイルス感染症の病理学的検索

  藤原千夏; 相原尚之; 小森園亮; 牧野晶子; 朝長啓造; 曽我玲子; 上家潤一

  日本獣医学会学術集会講演要旨集, 2019

  
• パーキンソン病とボルナ病ウイルス感染

  朝長 啓造; 渡辺 真紀子; 神谷 亘

  遺伝子医学, May 2000

  
• 中枢神経系におけるボルナ病ウイルス研究の進歩 (綜説シリーズ--現代医学の焦点(233))

  朝長 啓造; 小林 剛; 生田 和良

  日本臨床, Aug. 2001

  
• Reviewと研究 ボルナ病ウイルス

  朝長 啓造; 生田 和良

  Virus report, Nov. 2006

  
• ヒトの神経を冒す新しいウイルス感染症--ボルナ病ウイルス感染症 (特集 エマージングウイルス感染症--人類の新たな脅威となるウイルス病)

  朝長 啓造; 生田 和良

  遺伝, Feb. 1999

  
• The AP-1 binding site in the feline immunodeficiency virus long lymphocytes.

  Miyazawa Takayuki; Kohmoto Mariko; Kawaguchi Yasushi; Tomonaga Keizo

  Collected papers from the Institute of Immunological Science Hokkaido University, 1993

  
• 抗ボルナ病ウイルス抗体を認めた辺縁系脳炎の1例

  松永 秀典; 別宮 豪一; 狭間 敬憲; 田口 智己; 原元 燈; 上間 武; 朝長 啓造; 生田 和良

  NEUROINFECTION, Sep. 2005

  
• 哺乳動物ゲノムに潜むRNAウイルス化石

  堀江 真行; 朝長 啓造

  遺伝, Nov. 2010

  
• Bornaviruses

  TOMONAGA Keizo

  ウイルス, 01 Dec. 2012

  
• 鳥ボルナウイルスParrot bornavirus4のリバースジェネティクス法の確立

  小森園亮; 小森園亮; 藤野寛; 堀江真行; 堀江真行; KESSLER Susanne; RUNGE Solveig; 神田雄大; 神田雄大; 牧野晶子; 牧野晶子; RUBBENSTROTH Dennis; 朝長啓造; 朝長啓造; 朝長啓造

  日本ウイルス学会学術集会プログラム・予稿集(Web), 2019

  
• ユビナガコウモリゲノムに内在するボルナウイルス由来遺伝子は潜在的に機能性RNA結合タンパク質をコードする

  向井八尋; 向井八尋; 堀江真行; 堀江真行; 小林由紀; 小嶋将平; 小嶋将平; 前田健; 朝長啓造; 朝長啓造; 朝長啓造

  日本分子生物学会年会プログラム・要旨集(Web), 2018

  
• 日本国内の愛玩鳥繁殖場における鳥ボルナウイルス感染症の流行

  小森園亮; 小森園亮; 竹前喜洋; 上家潤一; 曽我玲子; 牧野晶子; 牧野晶子; 朝長啓造; 朝長啓造

  日本獣医学会学術集会講演要旨集, 2018

  
• Development of Borna Disease Virus Vector for Differentiation of Human iPSCs into Skeletal Muscle Cells

  Yumiko Komatsu; Dan Takeuchi; Hidetoshi Sakurai; Yasuhiro Ikeda; Yusuke Yamamoto; Tomoyuki Honda; Akiko Makino; Keizo Tomonaga

  MOLECULAR THERAPY, May 2017

  
• ユビナガコウモリ属コウモリのゲノムに内在化しているボルナウイルス由来配列の生物学的意義の探索

  向井八尋; 向井八尋; 堀江真行; 堀江真行; 小林由紀; 小嶋将平; 小嶋将平; 前田健; 朝長啓造; 朝長啓造

  日本進化学会大会プログラム・講演要旨集(Web), 2017

  
• ユビナガコウモリゲノムに内在する内在性ボルナウイルス様エレメントの基本的な性状解析と内在化年代の推定

  向井八尋; 向井八尋; 堀江真行; 堀江真行; 小嶋将平; 小嶋将平; 長田奈緒; 前田健; 朝長啓造; 朝長啓造

  日本獣医学会学術集会講演要旨集, 2017

  
• Improvement of the production of Borna disease virus vector

  A. Makino; R. Komorizono; M. Sakai; K. Tomonaga

  HUMAN GENE THERAPY, Nov. 2016

  
• A novel RNA virus-based episomal vector system for long-term stem cell modification

  A. Makino; R. Komorizono; S. J. Holditch; B. Lu; T. Honda; Y. Ikeda; K. Tomonaga

  HUMAN GENE THERAPY, Oct. 2015

  
• A novel RNA virus vector system for small RNA deliery based on Borna disease virus

  T. Honda; Y. Yamamoto; Y. Matsumoto; A. Makino; K. Tomonaga

  HUMAN GENE THERAPY, Oct. 2015

  
• The regulation of Borna disease virus production

  Akiko Makino; Tomoyuki Honda; Keizo Tomonaga

  The 14th Awaji International Forum on Infection and Immunity, Sep. 2015, Peer-reviewed

  
• IGF2 is involved in the regulation of Borna disease virus production.

  Akiko Makino; Tomoyuki Honda; Keizo Tomonaga

  Negative Strand RNA virus meeting 2015, Jun. 2015, Peer-reviewed

  
• IGF2によるボルナ病ウイルス粒子産生 制御機構の解析

  牧野晶子; 藤野寛; 平井悠哉; 惣福梢; 本田知之; 朝長啓造

  第4回Negative Strand Virus-Japan, Jan. 2015, Peer-reviewed

  
• ボルナ病ウイルス粒子産生に対する宿主因子IGF2の関与

  牧野晶子; 藤野寛; 平井悠哉; 惣福梢; 本田知之; 朝長啓造

  第62回日本ウイルス学会, Nov. 2014, Peer-reviewed

  
• ハダカデバネズミのゲノムに内在化したレトロウイルス様配列の解析

  牧野晶子; 宮沢孝幸; 鈴木善幸; 三浦恭子; 朝長啓造

  第157回日本獣医学会学術集会, Sep. 2014, Peer-reviewed

  
• 新規遺伝子トリボルナウイルス(ABV‐BF)の解析

  佐々悠木子; 堀江真行; 鈴木研太; 加藤真樹; 香川紘子; 鈴木和彦; 渋谷淳; CHANATHIP Thammakarn; 竹原一明; 古谷哲也; 本田知之; 朝長啓造; 岡ノ谷一夫; 水谷哲也

  日本獣医学会学術集会講演要旨集, 11 Aug. 2014

  
• Expression of IGF2 affects Borna disease virus production in infected cells

  Akiko Makino; Kan Fujino; Takuji Daito; Tomoyuki Honda; Keizo Tomonaga

  International Union of Microbiological Societies Congresses, Jul. 2014, Peer-reviewed

  
• ボルナウイルスの粒子産生制御機構の解析

  牧野晶子; 藤野寛; 大東卓史; 本田知之; 朝長啓造

  第3回Negative Strand Virus-Japan, Jan. 2014, Peer-reviewed

  
• ボルナ病ウイルスNタンパク質のアンキリン様配列を介したNF-κ B活性化阻害

  牧野晶子; 藤野寛; 惣福梢; 中村祥子; 本田知之; 朝長啓造

  第61回日本ウイルス学会, Nov. 2013, Peer-reviewed

  
• Inhibition of NF-κB activation by peptide derived from nucleoprotein of Borna disease virus.

  Akiko Makino; Kan Fujino; Kozue Sofuku; Shoko Nakamura; Tomoyuki Honda; Keizo Tomonaga

  15th International Negative Strand Virus Meeting, Jun. 2013, Peer-reviewed

  
• ウイルスタンパク質内のTLRシグナル伝達阻害ペプチドの探索と評価

  牧野晶子; 藤野寛; 惣福梢; 中村祥子; 伊藤睦美; 本田知之; 新矢恭子; 河岡義裕; 朝長啓造

  第六回ボルナウイルス研究会, Mar. 2013, Peer-reviewed

  
• ボルナウイルスの人への感染と病原性の検討:抗ウイルス剤リバビリンによる治療の試み

  松永秀典; 陸馨仙; 柳田誠; 富岡孝仁; 金井講治; 阪上由香子; 高岡謙吉; 高田宏宗; 木村亮; 本田知之; 朝長啓造

  総合病院精神医学, 2013

  
• ジリスゲノムより復元した内在性ボルナウイルスはボルナ病ウイルスの感染を阻害する

  藤野寛; 堀江真行; 本田知之; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2013

  
• 内在性ボルナ病ウイルス様エレメントによるボルナ病ウイルスの新しい制御機構

  本田知之; 小嶋将平; 牧野晶子; 藤野寛; 惣福梢; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2013

  
• A型インフルエンザウイルス感染におけるムチン型糖転移酵素GALNT3の機能解析

  中村祥子; 堀江真行; 安木真世; 大道寺智; 久野敦; 奥崎大介; 牧野晶子; 本田知之; 成松久; 中屋隆明; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2013

  
• A型インフルエンザウイルス感染におけるムチン型糖転移酵素GALNT3の機能解析

  中村祥子; 堀江真行; 安木真世; 大道寺智; 久野敦; 奥崎大介; 牧野晶子; 本田知之; 成松久; 中屋隆明; 朝長啓造

  日本分子生物学会年会プログラム・要旨集(Web), 2013

  
• A型インフルエンザウイルス感染によるムチン型糖転移酵素GALNT3の発現制御機序と意義の解析

  中村 祥子; 堀江 真行; 安木 真世; 奥崎 大介; 牧野 晶子; 本田 知之; 朝長 啓造

  日本生化学会大会プログラム・講演要旨集, Dec. 2012, Peer-reviewed

  
• A型インフルエンザウイルス感染細胞におけるmiRNAを介したGALNT3の発現制御に関する解析

  中村 祥子; 堀江 真行; 安木 真世; 奥崎 大介; 本田 知之; 朝長 啓造

  日本獣医学会学術集会講演要旨集, Mar. 2012, Peer-reviewed

  
• エキゾチック動物の感染症最前線 鳥類 ボルナウイルス感染症

  藤野寛; 藤野寛; 朝長啓造

  エキゾチック診療, 2012

  
• 内在性ボルナウイルス様Nエレメント1の転写制御機構の解明

  惣福梢; 本田知之; 藤野寛; 堀江真行; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2012

  
• Analysis of possible functions and evolutional roles of endogenous bornavirus elements in human genome.

  Tomonaga K

  International Bornaviras Meeting in Freiburg 2012. Department of Virology, University of Freiburg. 8-10 December 2012, 2012, Peer-reviewed

  
• Studies on bornavirus: towards opening a new avenue in RNA virus research.

  Tomonaga K

  Special seminar at Centre de Physiopathologie de Toulouse-Purpan, Toulouse, France. 7 December 2012., 2012, Peer-reviewed

  
• Characterization of Borna disease virus-induced RNA speckles in the nucleus.

  Honda T; Matsumoto Y; Makino A; Fujino K; Sofiiku K; Nakamura S; Tomonaga K

  The 11th Awaji International Forum on Infection and Immunity. 11-14 September 2012, 2012, Peer-reviewed

  
• Bornavirus: the development of a new paradigm for RNA virus research. Department of Molecular Medicine Seminar

  Tomonaga K

  MAYO clinic. Rochester, MN USA. 26 July 2012., 2012, Peer-reviewed

  
• Intranuclear persistence of Borna disease virus shows a novel life cycle of RNA virus using host chromosome.

  Matsumoto Y; Fujino K; Horie M; Nakamura S; Honda T; Schwemmle M; Tomonaga K

  The 10th International Student Seminar. Kyoto, 5-8 March 2012, 2012, Peer-reviewed

  
• ウイルスから謎解く生命現象: 共存と疾患

  朝長啓造

  中高温微生物センター病原部門セ ミナー. 山口大学. 山口. 2012 年11月10 日, 2012, Peer-reviewed

  
• ウイルス研究と生命科学

  朝長啓造

  ウイルス研究と生命科学,2012 年2 月27 日, 2012, Peer-reviewed

  
• ボルナウイルス感染症一総論

  朝長啓造

  日本産業動物獣医学会一教育講演「ボルナ病」 平成23年度日本獣医師会 獣医学術会年次大会. 札幌. 2012 年2月3-5日, 2012, Peer-reviewed

  
• ボルナウイルス 感染細胞における核内ウイルスRNP の制御機構の解明

  本田知之; 松本祐介; 牧野晶子; 藤野 寛; 惣福 梢; 中村祥子; 朝長啓造

  第35回日本分子生物学会年会. 福岡 2012 年12月11-14日, 2012, Peer-reviewed

  
• ヒト由来内在性ボルナウイルス様ヌクレオプロテイン‐2の機能解明

  藤野 寛; 堀江真行; 本田知之; 惣福 梢; 朝長啓造

  第60回日本ウイルス学会学術集会. 大阪 2012 年11月13-15日, 2012, Peer-reviewed

  
• ハダカデバネズミを用いた内在性ウイルス様配 列の検出とウイルス感受比の解析

  牧野晶子; 三浦恭子; 岡野栄之; 朝長啓造

  第60回日本ウイルス学会学術集会. 大阪 2012 年11月13-15日, 2012, Peer-reviewed

  
• ボルナ病ウイル ス核内構造物の存在意義の解明

  本田知之; 松本祐介; 牧野晶子; 藤野 寛; 惣福 梢; 中村祥子; 朝長啓造

  第60回日本ウイルス学会学術集会. 大阪 2012 年 11月13-15日, 2012, Peer-reviewed

  
• 日本の愛玩鳥におけるトリボ ルナウイルスの浸潤状況

  佐々悠木子; 岡崎洋子; 堀江真行; 水谷哲也; 藤野 寛; 古谷哲也; 長井 誠; 小島篤史; 水上昌也; 上田謙吾; 海老沢和荘; 伊本治子; 朝長啓造

  第154 回目本獣医学会学術集会. 岩手 2012 年9月14-16日, 2012, Peer-reviewed

  
• ウイルスの内在化と進化的意義の解析

  朝長啓造

  シンポジウム1. 第14回日本RNA学会年会. 仙台. 2012 年7月18-20日, 2012, Peer-reviewed

  
• ボルナ病ウイルスベクターの樹立と粒子形成機構の解明

  大東卓史; 朝長啓造

  第153 回日本獣医学会学術集会. 埼玉 2012 年3月27-29, 2012, Peer-reviewed

  
• 内在性ボルナウイルスEBLN の発現によるボルナ病ウイルスの感染阻害

  藤野 寛; 堀江真行; 本田知之; 大東卓史; 松本祐介; 朝長啓造

  第153 回日本獣医学会学術集会. 埼玉2012 年3月27-29日, 2012, Peer-reviewed

  
• Endogenous bornavirus-like nucleoproteins in human genome

  Keizo Tomonaga

  GENES & GENETIC SYSTEMS, Dec. 2011

  
• The discovery of endogenous non-retroviral RNA virus elements and their endogenization process.

  Horie M; Kobayashi Y; Honda T; Suzuki Y; Gojobori T; Tomonaga K

  第6回研究所ネットワーク国際シンポジウム. 東京. 2011年6月9日, 2011, Peer-reviewed

  
• Chromatin-dependent transcriptional regulation of Borna disease virus.

  Matsumoto Y; Horie M; Daito T; Fujino K; Omori H; Tomonaga K

  The 18th East-Asia Joint Symposium on Biomedical Research. Shanghai China. 7-9 December 2011., 2011, Peer-reviewed

  
• Endogenous bornaviruses reveal a novel evolutionary interaction between RNA viruses and hosts.

  Tomonaga K; Fujino K; Horie M

  The 18th East-Asia Joint Symposium on Biomedical Research. Shanghai China. 7-9 December 2011., 2011, Peer-reviewed

  
• ボルナウイルスの性状と鳥ボルナウイルス研究の現状

  朝長啓造

  第2 回ボルナウイルス研 究会公開シンポジウム. 大阪. 2011 年9 月21 日, 2011, Peer-reviewed

  
• 内在性ボルナウイルス因子の発見とその意義

  朝長啓造

  ワークショップ「ウイルスの進化学的研究の新展開」第83 回日本遺伝学会. 京都. 2011 年9 月20-23 日, 2011, Peer-reviewed

  
• ボルナウイルス-RNA ウイルス研究の新たな展開を目指して-

  朝長啓造

  平成23 年度京都大学ウイルス研究所学術講演会. 京都. 2011 年7 月5 日., 2011, Peer-reviewed

  
• Analyses for natural selection operating on endogenous Borna-like nucleoprotein (EBLN) elements in primates

  Yuki Kobayashi; Yoshiyuki Suzuki; Masayuki Horie; Keizo Tomonaga; Takashi Gojobori

  GENES & GENETIC SYSTEMS, Dec. 2010

  
• 潜伏感染と再活性化 9.ボルナ病ウイルスの持続感染と病態機構

  DAITO TAKUJI; TOMONAGA KEIZO

  化学療法の領域, 25 May 2010

  
• ボルナウイルスを用いた新規RNAウイルスベクターの開発

  大東卓史; 堀江真行; 藤野寛; 松本祐介; 本田知之; 朝長啓造

  日本RNA学会年会要旨集, 2010

  
• 鳥ボルナウイルス感染状況の調査

  堀江真行; 大東卓史; 藤野寛; 松本祐介; 朝長啓造

  日本獣医学会学術集会講演要旨集, 2010

  
• わが国における鳥ボルナウイルスの持続感染

  堀江真行; 上田謙吾; 上田亜希子; 大東卓史; 藤野寛; 松本祐介; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2010

  
• ボルナ病ウイルスのインテグレーションに関する研究

  堀江真行; 本田知之; 大東卓史; 藤野寛; 松本祐介; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2010

  
• ボルナ病ウイルス膜糖蛋白質と粒子形成機構の解析

  大東卓史; 堀江真行; 藤野寛; 松本祐介; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2010

  
• ボルナ病ウイルスの核内寄生メカニズムの解明

  松本祐介; 堀江真行; 大東卓史; 藤野寛; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2010

  
• 膜遺伝子欠損型ボルナ病ウイルスベクターの開発

  大東卓史; 松本祐介; 藤野寛; 堀江真行; 本田知之; 朝長啓造

  日本獣医学会学術集会講演要旨集, 2010

  
• マトリックス及びエンベロープ遺伝子欠損型ボルナウイルスベクターの構築

  藤野寛; 大東卓史; 堀江真行; 松本祐介; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2010

  
• 毛引き症のオオハナインコにおける鳥ボルナウイルス遺伝子の検出

  堀江真行; 上田謙吾; 藤野寛; 松本祐介; 大東卓史; 朝長啓造

  日本獣医学会学術集会講演要旨集, 2009

  
• ボルナウイルス属ウイルスのXおよびP蛋白質の相互作用の解析

  藤野寛; 堀江真行; 本田知之; 大東卓史; 松本祐介; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2009

  
• ボルナ病ウイルスのクロマチン結合に関与するウイルス因子の同定

  堀江真行; 松本祐介; 本田知之; 大東卓史; 藤野寛; 生田和良; 朝長啓造

  日本ウイルス学会学術集会プログラム・抄録集, 2009

  
• 鳥ボルナウイルスXおよびP遺伝子の相互作用の解析

  藤野寛; 堀江真行; 上田謙吾; 本田知之; 大東卓史; 松本祐介; 朝長啓造

  日本獣医学会学術集会講演要旨集, 2009

  
• A study of the prevention of PERV infection in pig to human xenotransplantation

  K Hazama; S Miyagawa; T Miyazawa; J Yamada; K Tomonaga; K Ota; H Matsuda; R Shirakura

  XENOTRANSPLANTATION, Sep. 2003

  
• A study of the prevention of PERV infection by siRNA

  S Miyagawa; J Yamada; K Hazama; A Yamamoto; T Miyazawa; K Tomonaga; R Shirakura

  XENOTRANSPLANTATION, Sep. 2003

  
• リンパ系細胞におけるネコスプーマウイルス感染と感染細胞に見られるアポトーシス

  池田靖弘; 板垣慎一; 深沢昌史; 筒井茂樹; 前田健; 朝長啓造; 宮沢孝幸; 望月雅美; 見上彪

  日本獣医学会学術集会講演要旨集, 1995

  
• ネコカリシウイルスF4株の非構造蛋白遺伝子の塩基配列の決定

  押鴨涼子; 遠矢幸伸; 朝長啓造; 川口寧; 前田健; 甲斐知恵子; 見上彪

  日本獣医学会学術集会講演要旨集, 1994

  
• 日本のFIV分離株のheterogeneity

  山田博司; 宮沢孝幸; 朝長啓造; 川口寧; 前田健; 遠矢幸伸; 甲斐知恵子; 見上彪

  日本獣医学会学術集会講演要旨集, 1993

  
• ネコカリキウイルスによるネコTリンパ球への持続感染とネコ免疫不全ウイルスに対する影響

  川口寧; 遠矢幸伸; 前田健; 宮沢孝幸; 朝長啓造; 甲斐知恵子; 見上彪

  日本獣医学会学術集会講演要旨集, 1992

  
• ネコCD8cDNAのクローニング

  宮沢孝幸; 豊崎朋子; 前田健; 川口寧; 朝長啓造; 遠矢幸伸; 甲斐知恵子; 見上彪

  日本獣医学会学術集会講演要旨集, 1992

  

Presentations

• Detection and functional elucidation of endogenous RNA viruses in the mammalian genomes.

  Keizo Tomonaga

  2021 Neo-Virology Symposium, 30 Sep. 2921

  
• Research Progress of orthobornaviruses in Kyoto University

  Keizo Tomonaga

  国立臺灣大学セミナー, 12 Dec. 2022, Invited

  
• Bornavirus Research: Exploring the Neovirology.

  Keizo Tomonaga

  The University of Toledo, Department of Medical Microbiology & Immunology Seminar, 20 Apr. 2022, Invited

  
• A novel intranuclear RNA vector system targeting stem cells and the central nervous system

  Keizo Tomonaga

  The 16th International Symposium of the Institute Network for Biomedical Sciences. KEY FORUM 2021 International Symposium, 12 Nov. 2021

  
• 新型コロナウイルスワクチン開発の現状と展望

  朝長啓造

  日本学術会議主催学術フォーラム, Invited

  
• Evolutionarily Acquired Functions of Endogenous RNA Viral Elements in Mammals.

  Keizo Tomonaga

  第67回日本ウイルス学会学術集会, 29 Oct. 2019, Invited

  
• Bornavirus: a new model of coevolution between RNA virus and host.

  Keizo Tomonaga

  日本細菌学会年次大会, 27 Mar. 2018, Invited

  
• ボルナウイルス： RNAウイルスと宿主の共進化

  朝長啓造

  第30回中国四国ウイルス研究会, 28 Jun. 2015, 中国四国ウイルス研究会

  
• マイナーウイルス研究の挑戦と醍醐味

  Keizo Tomonaga

  大阪大学微生物病研究所アドバンストセミナー, 18 Feb. 2015, 大阪大学微生物病研究所, Invited

  
• Life in the nucleus:the unknown relationship between an RNA virus and host cells

  Keizo Tomonaga

  JSPS Core-to-Core Program 1st International Symposium Intranuclear Infection and Host Immunity, 27 Jan. 2015, JSPS, Kyoto University, Invited

  
• Life in the nucleus: how and why bornavirus can coexist with the host.

  Keizo Tomonaga

  Wakate International Symposium, Discovery of Medical Sciences., 06 Nov. 2014, Tsukuba University

  
• RNA virus and small RNAs

  Keizo Tomonaga

  The 6th Japanese Association for RNAi, 28 Aug. 2014, Japanese Association for RNAi

  
• Bornavirus research: exploring new species and old members, State-of Art lecture “Bornavirus”

  Keizo Tomonaga

  XVI International Congress of Virology, 30 Jul. 2014, IUMS

  
• Bornavirus infection: a unique life style of an animal RNA virus in the DNA habitat.

  Keizo Tomonaga

  DNA Habitat and its RNA Inhabitants, 04 Jul. 2014

  
• ボルナウイルス研究：神経病原性から広がる基礎研究と応用．

  Keizo Tomonaga

  第18回日本神経ウイルス研究会, 20 Jun. 2014, 日本神経ウイルス研究会

  
• パンデミックから共存へ‐ゲノム解析が明らかにするウイルスとの共進化‐

  Keizo Tomonaga

  第28回 国立大学共同利用・共同研究拠点協議会 知の拠点セミナー, 17 Jan. 2014, 立大学共同利用・共同研究拠点協議会, Invited

  
• Cellular co-option of endogenous bornavirus-like elements in mammalian hosts

  Keizo Tomonaga

  第36回日本分子生物学会年会, 03 Dec. 2013, 日本分子生物学会年会

  
• Endogenous bornavirus-like elements: cellular co-option and impact on host evolution.

  Keizo Tomonaga

  1st Kyoto International Symposium on Virus-Host Coevolution, 03 Nov. 2013, IVR, Kyoto University

  
• Persistent infection of bornavirus reveals possible mechanism of intranuclear sensing of RNA virus infection.

  Keizo Tomonaga

  The 12th Awaji International Forum on Infection and Immunity., 10 Sep. 2013, Awaji International Forum

  
• 私たちのゲノムに潜むウイルスたち−敵か？味方か？−

  Keizo Tomonaga

  東京大学医科学研究所公開セミナー 「ラブラボ」．, 23 Jul. 2013, 東京大学, Invited

  
• RNAと染色体：ウイルス感染から探る生命現象．

  Keizo Tomonaga

  京都薬科大学腫瘍細胞生物学特論, 03 Jul. 2012, 京都薬科大学

  
• ボルナウイルスの感染と分子生物学

  Keizo Tomonaga

  東京大学大学院講義獣医学特論「動物ウイルス学の最前線」, 18 May 2012, 東京大学

  
• ボルナウイルス感染症−総論

  Keizo Tomonaga

  平成23年度日本獣医師会獣医学術会年次大会, 2012, 日本獣医師会

  
• Discovery of endogenous nonretroviral viruses in mammalian genomes: new insights into virus-host interaction.

  Keizo Tomonaga

  Singapore-Japan Joint Forum Emerging Concepts in Microbiology., 15 Nov. 2011, Singapore Society of Science and JSPS

  
• Virus within us: The novel interaction of RNA viruses and host genomes. Plenary lecture “Genome Virology”.

  Keizo Tomonaga

  XV International Congress of Virology., 11 Sep. 2011, IUMS

  

Books and Other Publications

• ネオウイルス学

  河岡, 義裕

  集英社, Mar. 2021

  Find Kyoto University's collection of books :

  
• 現代用語の基礎知識

  自由国民社

  自由国民社, Jan. 2021

  Find Kyoto University's collection of books :

  
• 京大発!フロンティア生命科学

  京都大学大学院生命科学研究科; 講談社サイエンティフィク

  講談社, Mar. 2018

  Find Kyoto University's collection of books :

  
• Cell surface receptors for viruses.

  Honda T; Tomonaga K, Joint work

  Springer, 2013, Not refereed

  
• Bornaviridae.

  Schwemmle M; Carbone KM; Tomonaga K; Garten W; Nowotny N, Joint work

  Academic Press, 2005, Not refereed

  
• Borna disease virus: Molecular virology

  Kishi M; Tomonaga K; Lai P; de la Torre JC, Joint work

  ASM Press, 2002, Not refereed

  
• Borna disease virus: Role in neurobehavioral disease.

  ASM Press, 2002, Not refereed

  
• Borna disease virus and Its Role in neurobehavioral disease

  ASM Press, 2002, Not refereed

  
• Borna disease virus: Spanning a century of science

  Tomonaga K; Carbone KM, Joint work

  ASM Press, 2002, Not refereed

  

Industrial Property Rights

• 特許6944692, 特願2017-049247, ボルナウイルスベクター及びその利用

  朝長 啓造

  
• 特願2015-114308, 目的遺伝子の発現誘導可能なウイルスベクター

  朝長 啓造

  
• 特許5299879, 特願特願2008-191285, ボルナ病ウイルスを利用するベクターおよびその利用

  朝長 啓造

  
• 特願特願2009-087608, ボルナ病ウイルスを利用するベクターおよびその利用

  朝長 啓造

  

Awards

• Sep. 1994

  The Japanese Society of Veterinary Science, Conference Award of the Japanese Society of Veterinary Science
• Sep. 1994

  The Japanese Society of Veterinary Science, The encouragement Award of the Japanese Society of Veterinary Science
• Oct. 2002

  The Japanese Society for Virology, Sugiura Award of the Japanese Society for Virology
• 12 Nov. 2017

  公益財団法人 野口英世記念会, Noguchi Hideyo Memorial Prize for Medicine

External funds: Kakenhi

• Exploring epigenomic perturbation by an episomal RNA virus vector

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 90:Biomedical engineering and related fields

  Kyoto University

  Keizo TOMONAGA

  From 09 Jul. 2021, To 31 Mar. 2023, Project Closed

  ウイルスベクター;幹細胞;遺伝子治療;エピゲノム;ボルナウイルス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K19909/
• Elucidation of the mechanisms of SARS-CoV-2 infection and airway epithelial barrier disruption

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields

  Kyoto University

  Koichi Omori

  From 09 Jul. 2021, To 31 Mar. 2024, Project Closed

  新型コロナウイルス;シュードウイルス;ヒトiPS細胞由来気道上皮;免疫不全ラット;Spikeタンパク質;COVID-19 モデル動物;COVID-19;ヒトiPS細胞由来気道上皮移植ラット;SARS-CoV-2 Spikeタンパク質;CRISPR/Cas9システム;ノックアウトスクリーニング;オミクロン株;CRISPR/CAS9;気道上皮;バリア破壊

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K19567/
• ネオウイルス学：生命の源流から超個体、そしてエコ・スフィアーへ

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  The University of Tokyo

  河岡 義裕

  From 01 Apr. 2021, To 31 Mar. 2022, Project Closed

  ウイルス;宿主との共生;多様性;生態系

  https://kaken.nii.ac.jp/grant/KAKENHI-WRAPUP-21H00456/
• Genome immunity: elucidation of the antiviral activity of endogenous bornaviruses and their utilization as functional resources

  Grant-in-Aid for Scientific Research (S)

  Broad Section F

  Kyoto University

  朝長 啓造

  From 31 Aug. 2020, To 31 Mar. 2025, Granted

  内在性ウイルス;ボルナウイルス;ゲノム免疫;共進化;ゲノム多様性;ウイルス免疫;内在性RNAウイルス;抗ウイルス作用

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H05682/
• ウイルス由来エピソーマルRNAを用いた革新的幹細胞遺伝子治療ベクターの創出

  Grant-in-Aid for Scientific Research (A)

  Medium-sized Section 90:Biomedical engineering and related fields

  Kyoto University

  朝長 啓造

  From 01 Apr. 2020, To 31 Mar. 2021, Discontinued

  ボルナウイルス;エピゾーマルRNA;ウイルスベクター;幹細胞;遺伝子治療;RNAウイルス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H00662/
• Development of a self-editing RNA viral vector to accelerate gene therapy for neurological diseases

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 49:Pathology, infection/immunology, and related fields

  Kyoto University

  Keizo Tomonaga

  From 28 Jun. 2019, To 31 Mar. 2021, Project Closed

  ボルナウイルス;ウイルスベクター;ADAR;Cas13;ADRA

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K22530/
• A novel cell transplantation therapy for ALS using scFv-secreting OPCs

  Grant-in-Aid for Scientific Research (B)

  Basic Section 52020:Neurology-related

  Shiga University of Medical Science

  Makoto Urushitani

  From 01 Apr. 2019, To 31 Mar. 2022, Project Closed

  筋萎縮性側索硬化症;抗体;SOD1;移植;ウイルスベクター;オリゴデンドロサイト前駆細胞;オリゴデンドロサイト前駆細胞（OPC);再生;scFv;細胞間伝搬;一本鎖抗体(scFv);細胞移植治療;superoxide dismutase 1

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19H03573/
• Risk assessment and pathogenicity of highly pathogenic emerging bornavirus

  Grant-in-Aid for Scientific Research (C)

  Basic Section 42020:Veterinary medical science-related

  Kyoto University

  Akiko Makino

  From 01 Apr. 2018, To 31 Mar. 2021, Project Closed

  人獣共通感染症;高病原性;RNAウイルス;ウイルス;リバースジェネティクス;病原性;ボルナウイルス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18K05991/
• Study on DNA damage responses for regulation of intranuclear RNA viruses

  Grant-in-Aid for Scientific Research (B)

  Kyoto University

  Keizo Tomonaga

  From 01 Apr. 2017, To 31 Mar. 2020, Project Closed

  RNAウイルス;細胞核;DNA損傷

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17H04083/
• Neo-virology: the raison d'etre of viruses

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  The University of Tokyo

  Yoshihiro Kawaoka

  From 30 Jun. 2016, To 31 Mar. 2023, Project Closed

  ウイルス;国際共同研究;ネットワーク構築;宿主との共生;生態

  https://kaken.nii.ac.jp/grant/KAKENHI-INTERNATIONAL-16K21723/
• Comprehensive analysis on detection and function of endogenous RNA viruses

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  Keizo Tomonaga

  From 30 Jun. 2016, To 31 Mar. 2021, Project Closed

  内在性ウイルス;ボルナウイルス;共進化;外適応;機械学習;内在性RNAウイルス;RNAウイルス;進化;ビッグデータ

  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-16H06430/
• Neo-virology: the raison d'etre of viruses

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  The University of Tokyo

  Yoshihiro Kawoaka

  From 30 Jun. 2016, To 31 Mar. 2021, Project Closed

  ウイルス;生態系;共進化;共生;多様性;宿主との共生;生態

  https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-16H06429/
• RNAウイルス複製場の形成と崩壊における核内コンピテンシーの解明

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  朝長 啓造

  From 01 Apr. 2015, To 31 Mar. 2017, Discontinued

  ウイルス感染;細胞核;ボルナウイルス;ウイルス

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-15H01259/
• An RNA-dependent RNA polymerase gene in the genomes of bats

  Grant-in-Aid for Young Scientists (B)

  Kagoshima University

  Masayuki Horie

  From 01 Apr. 2014, To 31 Mar. 2016, Project Closed

  内在性ウイルス様エレメント;共進化;RNA依存性RNAポリメラーゼ;ボルナウイルス;内在化

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26850208/
• Analysis on RNA virus sensing machinery in the cell nucleus

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Tomonaga Keizo

  From 01 Apr. 2014, To 31 Mar. 2016, Project Closed

  ウイルス;細胞核;RNA;自然免疫

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26670225/
• Infection memory: study on antiviral functions of endogenous viruses

  Grant-in-Aid for Scientific Research (A)

  Kyoto University

  Keizo Tomonaga

  From 01 Apr. 2014, To 31 Mar. 2017, Project Closed

  内在性ウイルス;ボルナウイルス;ウイルス抵抗性;外適応;進化;内在性RNAウイルス;共進化;感染防御;ウイルス;ゲノム

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26253027/
• RNAウイルスゲノムに由来するヒト機能性遺伝子の探索

  Grant-in-Aid for Challenging Exploratory Research

  Osaka University

  朝長 啓造

  From 28 Apr. 2011, To 31 Mar. 2012, Declined

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23659230/
• 感染グリア病態学:ウイルスから解き明かすグリア細胞の新機能

  Grant-in-Aid for Challenging Exploratory Research

  Osaka University

  朝長 啓造

  From 01 Apr. 2009, To 31 Mar. 2011, Project Closed

  ボルナ病ウイルス;グリア細胞;感染病態;シナプス;神経疾患

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21659114/
• ボルナウイルス感染のエピジェネティック制御機構:RNAウイルスの新しい病原性

  Grant-in-Aid for Scientific Research (B)

  Osaka University

  朝長 啓造

  From 01 Apr. 2009, To 31 Mar. 2012, Project Closed

  ボルナ病ウイルス;RNAウイルス;病原性;持続感染;エピジェネティクス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21390139/
• 細胞核で持続感染するマイナス鎖RNAウイルスの複製基盤の解明

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Osaka University

  朝長 啓造

  From 01 Apr. 2009, To 31 Mar. 2011, Project Closed

  ボルナ病ウイルス;RNAウイルス;細胞核;持続感染;クロマチン

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-21022023/
• 細胞核で持続感染するマイナス鎖RNAウイルスの複製基盤の解明

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Osaka University

  朝長 啓造

  From 01 Apr. 2007, To 31 Mar. 2009, Project Closed

  ボルナ病ウイルス;RNAウイルス;細胞核;持続感染;クロマチン;RNA ウイルス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19041038/
• Overcome of virus-induced neurological disorders : a novel strategy based on the functions of a pattern recognition receptor, RAGE

  Grant-in-Aid for Scientific Research (B)

  Osaka University

  Keizo TOMONAGA

  From 01 Apr. 2006, To 31 Mar. 2008, Project Closed

  ボルナ病ウイルス;持続感染;ウイルス性脳疾患;RAGE;S100B;脳炎抑制;中枢神経系;脳炎, Boma disease virus;Persistent infection;Neurological disorders;RAGE;S100B;Virus-induced encephalitis

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18390139/
• グリア細胞機能障害と機能性精神疾患:ウイルス蛋白質を利用した発症分子機構の解明

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Osaka University

  朝長 啓造

  From 01 Apr. 2005, To 31 Mar. 2006, Project Closed

  ボルナ病ウイルス;グリア細胞;ウイルス感染;機能性精神疾患;動物モデル

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17025027/
• 持続感染期におけるモノネガウイルス・ゲノムRNAの安定化機構の解析

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Osaka University

  朝長 啓造

  From 01 Apr. 2004, To 31 Mar. 2006, Project Closed

  ボルナ病ウイルス;持続感染;RNA;クロマチン;HMGB1

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16017257/
• 新しい学習記憶障害モデル:ウイルス蛋白質を利用したシナプス脆弱化機構の解析

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Osaka University

  朝長 啓造

  From 01 Apr. 2004, To 31 Mar. 2005, Project Closed

  ボルナ病ウイルス;持続感染;シナプス;ストレス応答

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16015276/
• Overcome of virus-induced neurological disorders: analysis of neurological mechanisms inducing viral persistent infection in the central nervous system

  Grant-in-Aid for Scientific Research (B)

  Osaka University

  Keizo TOMONAGA

  From 01 Apr. 2003, To 31 Mar. 2006, Project Closed

  ボルナ病ウイルス;中枢神経系;持続感染;RAGE;ウイルス病原性;脳内免疫;感染病態, Borna disease virus;Central nervous system;Persistent Infection;RAGE;Viral neuropathogenesis;CNS immunity

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15390148/
• 持続感染期におけるモノネガウイルス・ゲノムRNAの安定化機序の解析

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Osaka University

  朝長 啓造

  From 01 Apr. 2003, To 31 Mar. 2004, Project Closed

  モノネガウイルス;ボルナ病ウイルス;持続感染;ゲノムRNA;中枢神経系;ウイルス病原性

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15019056/
• Studies on the heterogeneity in the correlation between Borna disease virus location in the central nervous system(CNS) and induced CNS pathogenesis

  Grant-in-Aid for Scientific Research (B)

  Osaka University

  Kazuyoshi IKUTA

  From 01 Apr. 2002, To 31 Mar. 2005, Project Closed

  ボルナ病ウイルス;中枢神経系疾患;トランスジェニックマウス;持続感染;精神疾患;ストレス;HMGB1;リン酸化蛋白質;神経変性疾患;パーキンソン病;アルツハイマー病;運動器障害;熱ショック蛋白質;RAGE;リン酸蛋白質;加齢;神経網, Borna disease virus;central nervous system;transgenic mouse;persistent infection;psychiatric disorder;stress;HMGB1;phosphoprotein

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14370102/
• Regulation of Borna disease virus (BDV) phosphoprotein expression : Implication for BDV neuropathogenesis

  Grant-in-Aid for Scientific Research (C)

  Osaka University

  Keizo TOMONAGA

  From 01 Apr. 2001, To 31 Mar. 2003, Project Closed

  ボルナ病ウイルス;中枢神経系;持続感染;ウイルス蛋白質;神経病原性;感染病態;ウイルス病原性;ボルナ菌ウイルス;転写, Borna disease virus;Central nervous system;Persistent Infection;Viral protein;Neuropathogenesis

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13670297/
• ボルナ病ウイルス感染による神経突起伸張因子の機能阻害と脳成熟への影響

  Grant-in-Aid for Scientific Research on Priority Areas

  Biological Sciences

  Osaka University

  朝長 啓造

  From 01 Apr. 2001, To 31 Mar. 2003, Project Closed

  ボルナ病ウイルス;中枢神経系;神経突起伸長因子;持続感染;脳成熟;神経病態;ウイルス病原性;神経系;宿主因子;トランスジェニックマウス

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13035027/
• パーキンソン病患者脳内神経細胞の破壊とボルナ病ウイルス感染

  Grant-in-Aid for Scientific Research on Priority Areas (A)

  Osaka University

  生田 和良

  From 01 Apr. 2000, To 31 Mar. 2001, Project Closed

  ボルナ病ウイルス;パーキンソン病;黒質;線条体;トランスジェニックマウス;神経栄養因子;神経突起伸張因子;リン酸化蛋白

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12031211/
• 心臓血管外科領域におけるiPS細胞技術を用いた新規遺伝子治療ベクターの開発

  Grant-in-Aid for Scientific Research (C)

  Basic Section 55030:Cardiovascular surgery-related

  Kyoto University

  池田 義

  From 01 Apr. 2023, To 31 Mar. 2026, Granted

  マイクロRNA;ドラッグデリバリーシステム

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23K08232/
• 次世代ウイルスベクターを用いたウイルス性脳炎に対する幹細胞核酸療法の構築

  Grant-in-Aid for Challenging Research (Exploratory)

  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields

  Kyoto University

  朝長 啓造

  From 28 Jun. 2024, To 31 Mar. 2026, Granted

  ウイルスベクター;遺伝子細胞治療;ウイルス性脳炎;間葉系肝細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24K22131/

External funds: others

• 新規RNAウイルスベクターを用いた遺伝子治療薬の開発

  JST, 研究成果展開事業 大学発新産業創出プログラム（START）

  From 01 Oct. 2021, To 31 Mar. 2024

  朝長啓造

  代表
• 核内複製というRNAウイルスの持続感染戦略の解明

  国立研究開発法人日本医療研究開発機構, 感染症研究革新イニシアティブ（J-PRIDE）

  From 01 Jul. 2017, To 31 Mar. 2020

  朝長啓造

  代表
• 筋萎縮性側索硬化症の病原タンパク質に対する自己分解型細胞内抗体の実用化に向けた前臨床研究

  AMED, 難治性疾患実用化研究事業

  From 01 Oct. 2014, To 31 Mar. 2019

  漆谷真

  分担
• RNAi型医薬品を標的組織ならびに多能性幹細胞で持続的に発現させるウイルスベクター技術の開発

  AMED, 革新的バイオ医薬品創出基盤技術開発事業

  From 01 Oct. 2014, To 31 Mar. 2019

  朝長啓造

  代表
• ウイルス感染と宿主応答の総合的理解に向けた国際研究拠点形成 （平成26年度分）

  研究拠点形成事業　A.先端拠点形成型

  From 01 Apr. 2014, To 31 Mar. 2015

  朝長　啓造
• ウイルス感染と宿主応答の総合的理解に向けた国際研究拠点形成 （平成27年度分）

  研究拠点形成事業　A.先端拠点形成型

  From 01 Apr. 2015, To 31 Mar. 2016

  朝長　啓造
• ウイルス感染と宿主応答の総合的理解に向けた国際研究拠点形成 （平成28年度分）

  研究拠点形成事業　A.先端拠点形成型

  From 01 Apr. 2016, To 31 Mar. 2017

  朝長　啓造
• ウイルス感染と宿主応答の総合的理解に向けた国際研究拠点形成 （平成29年度分）

  研究拠点形成事業　A.先端拠点形成型

  From 01 Apr. 2017, To 31 Mar. 2018

  朝長 啓造
• ウイルス感染と宿主応答の総合的理解に向けた国際研究拠点形成 （平成30年度分）

  研究拠点形成事業　A.先端拠点形成型

  From 01 Apr. 2018, To 31 Mar. 2019

  朝長 啓造
• 低分子RNA治療を実現するための新規RNAウイルスベクタープラットフォームの創製

  JSPS「最先端・次世代研究開発支援プログラム」

  From Mar. 2011, To Mar. 2014

  代表

Education

Teaching subject(s)

• From 01 Apr. 2024, To 31 Mar. 2025

  Introduction to Biology and Life Science

  N484, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Course in Immunology and Human Disorders

  1031, Fall, Graduate School of Biostudies, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Experiments in Systemic Life Sciences

  5013, Fall, Graduate School of Biostudies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Experiments in Systemic Life Sciences

  5013, Spring, Graduate School of Biostudies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar C

  2008, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar B

  2007, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar B

  2007, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar D

  2009, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar D

  2009, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar C

  2008, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar A

  2006, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar A

  2006, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar

  2005, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  ILAS Seminar

  Z001, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Course in Immunology and Human Disorders

  1031, Spring, Graduate School of Biostudies, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Molecular Genetics II

  3726, Spring, Faculty of Science, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar C

  2008, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar B

  2007, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar B

  2007, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar D

  2009, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar D

  2009, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar C

  2008, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar

  2005, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar A

  2006, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar A

  2006, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar

  2005, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Experiments in Systemic Life Sciences

  5013, Spring, Graduate School of Biostudies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Experiments in Systemic Life Sciences

  5013, Fall, Graduate School of Biostudies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar

  2005, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar B

  2007, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Introduction to Biology and Life Science

  N484, Spring, Institute for Liberal Arts and Sciences, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar

  2005, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar D

  2009, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Experiments in Systemic Life Sciences

  5013, Spring, Graduate School of Biostudies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar D

  2009, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar A

  2006, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar B

  2007, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Experiments in Systemic Life Sciences

  5013, Fall, Graduate School of Biostudies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Molecular Genetics II

  3726, Spring, Faculty of Science, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar C

  2008, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Course in Immunology and Human Disorders

  1031, Spring, Graduate School of Biostudies, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar C

  2008, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar A

  2006, Fall, Graduate School of Biostudies, 5
• From Apr. 2011, To Mar. 2012

  微生物学

  Year-long, 医学部
• From Apr. 2012, To Mar. 2013

  Virus and Life Science

  Fall, 全学共通科目
• From Apr. 2012, To Mar. 2013

  Perspectives on Life Science B

  Fall, 全学共通科目
• From Apr. 2012, To Mar. 2013

  The Front Line of Life Science Research II

  Spring, 全学共通科目
• From Apr. 2013, To Mar. 2014

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2013, To Mar. 2014

  Advanced Course in Immunology and Human Disorders

  Spring, 生命科学研究科
• From Apr. 2013, To Mar. 2014

  Study of Life Science II

  Fall, 全学共通科目
• From Apr. 2013, To Mar. 2014

  Virus and Life Science

  Fall, 全学共通科目
• From Apr. 2013, To Mar. 2014

  The Front Line of Life Science Research II

  Spring, 全学共通科目
• From Apr. 2014, To Mar. 2015

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2014, To Mar. 2015

  Advanced Course in Immunology and Human Disorders

  Spring, 生命科学研究科
• From Apr. 2014, To Mar. 2015

  Experimental Course and Seminar l

  Year-long, 生命科学研究科
• From Apr. 2014, To Mar. 2015

  Experimental Course and Seminar 2

  Year-long, 生命科学研究科
• From Apr. 2014, To Mar. 2015

  Advanced Experiments in Systemic Life Sciences

  Year-long, 生命科学研究科
• From Apr. 2014, To Mar. 2015

  Study of Life Science II

  Fall, 全学共通科目
• From Apr. 2014, To Mar. 2015

  Virus and Life Science

  Fall, 全学共通科目
• From Apr. 2014, To Mar. 2015

  The Front Line of Life Science Research II

  Spring, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2015, To Mar. 2016

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2015, To Mar. 2016

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2015, To Mar. 2016

  Virus and Life Science

  Fall, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Study of Life Science II

  Fall, 全学共通科目
• From Apr. 2015, To Mar. 2016

  Advanced Course in Immunology and Human Disorders

  Fall, 生命科学研究科
• From Apr. 2015, To Mar. 2016

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2015, To Mar. 2016

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2016, To Mar. 2017

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2016, To Mar. 2017

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2016, To Mar. 2017

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2016, To Mar. 2017

  Introduction to Biology and Life Science

  Spring, 全学共通科目
• From Apr. 2016, To Mar. 2017

  Advanced Course in Immunology and Human Disorders

  Spring, 生命科学研究科
• From Apr. 2016, To Mar. 2017

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2016, To Mar. 2017

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2017, To Mar. 2018

  Molecular Genetics II

  Spring, 理学部
• From Apr. 2017, To Mar. 2018

  Microbiology

  Year-long, 医学部（人間健康科学科）
• From Apr. 2017, To Mar. 2018

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2017, To Mar. 2018

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Course in Immunology and Human Disorders

  Fall, 生命科学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2017, To Mar. 2018

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Molecular Genetics II

  Spring, 理学部
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar A

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar A

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar B

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar B

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar C

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar C

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar D

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar D

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Introduction to Biology and Life Science

  Spring, 全学共通科目
• From Apr. 2018, To Mar. 2019

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Molecular Genetics II

  Spring, 理学部
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar A

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar A

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar B

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar B

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar C

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar C

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar D

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar D

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Course in Immunology and Human Disorders

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Molecular Genetics II

  Spring, 理学部
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Introduction to Biology and Life Science

  Spring, 全学共通科目
• From Apr. 2020, To Mar. 2021

  Advanced Course in Immunology and Human Disorders

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Molecular Genetics II

  Spring, 理学部
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Course in Immunology and Human Disorders

  Spring, 生命科学研究科

Participation in PhD Defense

• Insights into the structure of Lloviu cuevavirus nucleoprotein-RNA complex through cryo-EM

  HU SHANGFAN, Graduate School of Biostudies, Sub-chief Examiner

  25 Mar. 2024
• Evolutional transition of HBV genome during the persistent infection determined by single-molecule real-time sequencing

  ARASAWA SOICHI, Graduate School of Medicine, Chief Examiner

  24 Jul. 2023
• Regulation of antiviral responses by RIG-I dissociation from dsRNA

  Jung Hyun Im, Graduate School of Biostudies, Sub-chief Examiner

  24 Nov. 2023
• iPSC-derived mesenchymal cells that support alveolar organoid development

  TAMAI KOJI, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2023
• The interferon-stimulated gene product HELZ2 destabilizes human LINE-1 RNA to inhibit LINE-1 retrotransposition and the associated typeⅠinterferon response

  AHMAD LUQMAN BIN ABDUL FATAH, Graduate School of Biostudies, Sub-chief Examiner

  23 Mar. 2023
• マールブルグウイルス核タンパク質-RNA複合体の立体構造解析

  FUJIHARU YOKO, Graduate School of Biostudies, Sub-chief Examiner

  26 Sep. 2022
• マウス表皮T細胞の発生における胎生期および新生仔期T細胞受容体シグナルの役割

  SUDO KOICHI, Graduate School of Biostudies, Sub-chief Examiner

  23 May 2022
• Investigation of Innate Immune Responses in Eptesicus Bat Cells via Comprehensive Analysis

  LIN, HSIEN-HEN, Graduate School of Biostudies, Chief Examiner

  23 Mar. 2022
• The Non-structural Protein NSs of SFTSV Causes an NF-κB dependent cytokine storm

  JUMANA KHALIL, Graduate School of Biostudies, Sub-chief Examiner

  26 Jul. 2021
• コウモリゲノムに内在するボルナウイルス様配列miEBLN-1の分子進化学的解析および機能探索

  MUKAI YAHIRO, Graduate School of Biostudies, Chief Examiner

  23 Mar. 2022
• 脊椎動物のゲノムに存在するボルナウイルスの分子化石を用いた古ウイルス学研究

  KAWASAKI JUNNA, Graduate School of Biostudies, Chief Examiner

  23 Mar. 2022
• オルソボルナウイルスの宿主特異性に関わる分子機構の研究

  KOMORIZONO RYO, Graduate School of Biostudies, Chief Examiner

  23 Mar. 2022
• Pneumonia Caused by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza Virus: A Multicenter Comparative Study

  OI ISSEI, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2022
• BUD23-TRMT112 mediates the chromosomal tethering of Borna disease virus and catalyzes the internal m7G methylation in viral RNA

  BEA CLARISE BALUYOT GARCIA, Graduate School of Biostudies, Chief Examiner

  24 Sep. 2021
• ラッサウイルスの感染を阻害する新たな化合物の同定

  TAKENAGA TORU, Graduate School of Biostudies, Sub-chief Examiner

  24 Jan. 2022
• Adenovirus infection after allogeneic hematopoietic stem cell transplantation

  ONDA YOSHIYUKI, Graduate School of Medicine, Sub-chief Examiner

  26 Jul. 2021
• CAGE-seq reveals that HIV-1 latent infection does not trigger unique cellular responses in a Jurkat T cell model

  MATSUI HIROYUKI, Graduate School of Medicine, Chief Examiner

  26 Jul. 2021
• Simple derivation of skeletal muscle from human pluripotent stem cells using temperature-sensitive Sendai virus vector

  TAN GHEE WAN, Graduate School of Medicine, Sub-chief Examiner

  23 Mar. 2022

Part-time lecturer

• From 08 Apr. 2020, To 03 Sep. 2020

  獣医環境科学特別講義

  公立大学法人大阪

Administration

School management (title, position)

• From 01 Apr. 2022, To 31 Mar. 2024

  感染症モデル研究センター センター長
• 次世代研究者育成センター専門委員会　委員
• From 01 Apr. 2012, To 30 Sep. 2016

  ウィルス研究所附属感染症モデル研究センター長
• From 01 Oct. 2016

  動物実験委員会　委員
• From 01 Oct. 2016, To 31 Mar. 2018

  ウィルス・再生医科学研究所附属感染症モデル研究センター長
• From 01 Oct. 2016, To 31 Mar. 2020

  感染症モデル研究センター長
• From 01 Apr. 2018, To 31 Mar. 2020

  医学研究科先端研究基盤共用促進事業検討WG　メンバー
• From 01 Oct. 2016, To 31 Mar. 2022

  感染症モデル研究センター センター長

Faculty management (title, position)

• From 01 Apr. 2024

  広報委員会　委員長
• From 01 Apr. 2024

  医生物学研究所　研究支援室　共同利用機器ユニット
• From 01 Apr. 2024

  医生物学研究所　研究支援室　広報ユニット
• From 01 Apr. 2024

  医生物学研究所　研究支援室　共同研究拠点推進ユニット　ユニット長
• From 01 Apr. 2022

  業績評価委員会　委員長
• From 01 Apr. 2022

  予算委員会（医生物学研究所）
• From 01 Apr. 2022

  ウイルス・幹細胞システム医生物学共同研究拠点専門委員会　委員
• From 01 Apr. 2022

  ウイルス・幹細胞システム医生物学共同研究拠点運営委員会　委員長
• From 01 Apr. 2022

  施設設備委員会　委員
• From 01 Jul. 2021

  感染症モデル研究センター霊長類施設運営委員会　委員長
• From 01 Jul. 2021

  感染症モデル研究センター運営委員会　委員
• From 01 Apr. 2022

  人権委員会　委員長
• From 01 Apr. 2022

  副所長（医生物学研究所）
• From 01 Apr. 2024, To 31 Mar. 2026

  医学研究科病原体等安全管理委員会　委員
• From 01 Apr. 2011, To 31 Mar. 2013

  予算委員会　委員
• From 01 Oct. 2016

  病原体安全管理委員会　委員
• From 01 Oct. 2016

  動物実験員会　委員
• From 01 Apr. 2011, To 31 Mar. 2015

  広報委員会　委員
• From 01 Apr. 2011, To 31 Mar. 2013

  化学物質管理委員会　委員
• 防火対策委員会　委員
• From 01 Apr. 2014, To 31 Mar. 2017

  霊長類委員会　委員長
• From 01 Apr. 2013, To 31 Mar. 2015

  自己点検・評価委員会　委員
• From 01 Apr. 2012, To 30 Sep. 2016

  病原体安全管理委員会　委員
• From 01 Apr. 2013, To 31 Mar. 2017

  防災対策委員会　委員
• From 01 Apr. 2016, To 31 Mar. 2017

  職員等配置検討委員会 　委員
• From 01 Apr. 2016, To 31 Mar. 2017

  研究データ保全委員会　委員
• From 01 Oct. 2016, To 30 Jun. 2021

  ウイルス動物実験専門委員会　委員
• From 01 Oct. 2016, To 30 Jun. 2021

  霊長類動物実験専門委員会　委員長
• From 01 Apr. 2019, To 31 Mar. 2021

  （旧ウイルス研）予算委員会
• From 01 Oct. 2016, To 31 Mar. 2018

  ウイルス感染症・生命科学先端融合的共同研究拠点運営委員会　委員
• From 01 Oct. 2016, To 31 Mar. 2018

  ウイルス感染症・生命科学先端融合的共同研究拠点専門委員会　委員
• From 01 Apr. 2018, To 31 Mar. 2022

  ウイルス感染症・生命科学先端融合的共同研究拠点運営委員会　委員長
• From Apr. 2018, To 31 Mar. 2022

  ウイルス感染症・生命科学先端融合的共同研究拠点専門委員会　委員長
• From 06 May 2021, To 03 Mar. 2022

  ウイルス・再生医科学研究所予算委員　副委員長