Basic Information

Faculty

• Faculty of Integrated Human Studies

Concurrent Affiliation

• Institute for Life and Medical Sciences (LiMe), 生命システム研究部門 幹細胞デコンストラクション分野, 教授

Academic Degree

• 修士（生命科学）(京都大学)
• 博士（生命科学）(京都大学)

Research History

• Kyoto University

Profile

• Profile

  2003年 大阪大学 工学部 応用自然科学科卒業
  
  2005年 京都大学大学院 生命科学研究科修士課程修了
  
  2008年 京都大学大学院 生命科学研究科博士課程修了
  
  2008年 博士（生命科学）の学位取得（京都大学）
  
  
  2007年 日本学術振興会 特別研究員（DC2）・京都大学ウイルス研究所
  
  2008年 日本学術振興会 特別研究員（PD）・京都大学ウイルス研究所
  
  2009年 京都大学ウイルス研究所・特定研究員(産官学連携)
  
  2009年 科学技術振興機構(JST) さきがけ研究者
  
  2011年 京都大学 白眉センター・「白眉研究者」（特定准教授）
  
  2013年 京都大学医学研究科・メディカルイノベーションセンター・SKプロジェクト・神経新生研究グループ・Principal Investigator (兼任)
  
  2014年 科学技術振興機構(JST) さきがけ研究者 (兼任)
  
  2016年 京都大学 生命科学研究科・特定准教授 (卓越研究員)
  
  2018年 京都大学 生命科学研究科・教授

ID,URL

• ORCID ID

  0000-0001-9728-481X

• J-Global ID

  201401039386656977

• External link

  https://brainnetworks.jimdofree.com

Website(s) (URL(s))

• http://imayoshi.web.fc2.com/Itaru_Imayoshi_Ph.D./_Home.html
• https://brainnetworks.jimdofree.com/挨拶/

researchmap URL

• https://researchmap.jp/imayoshi_itaru

Research

Research Topics, Overview of the research

• Research Topics

  I study neural development, stem cell biology, and plasticity of the brain.

• Overview of the research

  I have studied neural development, stem cell biology, and plasticity of the brain. Especially, my research focus is bHLH transcriptional factors and neurogenesis in the postnatal/adult brain.

Research Areas

• Life sciences, Neuroscience - general

Papers

• Dopaminergic neurons in the paraventricular hypothalamus extend the food consumption phase.

  Winda Ariyani; Chiharu Yoshikawa; Haruka Tsuneoka; Izuki Amano; Itaru Imayoshi; Hiroshi Ichinose; Chiho Sumi-Ichinose; Noriyuki Koibuchi; Tadahiro Kitamura; Daisuke Kohno

  Proceedings of the National Academy of Sciences of the United States of America, Apr. 2025

  
• A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements

  Marito Hayashi; Miriam Gullo; Gokhan Senturk; Stefania Di Costanzo; Shinji C. Nagasaki; Ryoichiro Kageyama; Itaru Imayoshi; Martyn Goulding; Samuel L. Pfaff; Graziana Gatto

  02 Aug. 2023, Peer-reviewed

  
• A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements

  Marito Hayashi; Miriam Gullo; Gokhan Senturk; Stefania Di Costanzo; Shinji C. Nagasaki; Ryoichiro Kageyama; Itaru Imayoshi; Martyn Goulding; Samuel L. Pfaff; Graziana Gatto

  21 Mar. 2023

  
• Scale space calibrates present and subsequent spatial learning in Barnes maze in mice

  Yuto Tachiki; Yusuke Suzuki; Mutsumi Kurahashi; Keisuke Oki; Özgün Mavuk; Takuma Nakagawa; Shogo Ishihara; Yuichiro Gyoten; Akira Yamamoto; Itaru Imayoshi

  15 Dec. 2022, Peer-reviewed, Corresponding author

  
• Scale space calibrates present and subsequent spatial learning in Barnes maze in mice

  Yuto Tachiki; Yusuke Suzuki; Mutsumi Kurahashi; Keisuke Oki; Özgün Mavuk; Takuma Nakagawa; Shogo Ishihara; Yuichiro Gyoten; Akira Yamamoto; Itaru Imayoshi

  eneuro, 11 May 2023, Peer-reviewed, Corresponding author

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• Enhancement of Vivid-based photo-activatable Gal4 transcription factor in mammalian cells

  Shinji C. Nagasaki; Tomonori D. Fukuda; Mayumi Yamada; Yusuke III Suzuki; Ryo Kakutani; Adam T. Guy; Itaru Imayoshi

  Cell Structure and Function, 08 Feb. 2023, Peer-reviewed, Corresponding author

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• A multicolor suite for deciphering population coding of calcium and cAMP in vivo

  Tatsushi Yokoyama; Satoshi Manita; Hiroyuki Uwamori; Mio Tajiri; Itaru Imayoshi; Sho Yagishita; Masanori Murayama; Kazuo Kitamura; Masayuki Sakamoto

  Nature Methods, 21 Mar. 2024, Peer-reviewed

  
• Dynamic gene networks in neural stem cell regulation

  Kageyama, R.; Ohtsuka, T.; Shimojo, H.; Imayoshi, I.

  Stem Cells: From Basic Research to Therapy, Volume 1: Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms, 2014

  
• Separate optogenetic manipulation of Nerve/glial antigen 2 (NG2) glia and mural cells using the NG2 promoter

  Mitsuhiro Oishi; Stefan Passlick; Yoshihiko Yamazaki; Miyuki Unekawa; Ruka Adachi; Mayumi Yamada; Itaru Imayoshi; Yoshifumi Abe; Christian Steinhäuser; Kenji F. Tanaka

  Glia, 27 Sep. 2022, Peer-reviewed

  
• Regulatory Mechanism of Neural Progenitor Cells Revealed by Optical Manipulation of Gene Expressions

  Itaru Imayoshi; Mayumi Yamada; Yusuke Suzuki

  Make Life Visible, 2020, Peer-reviewed

  
• Functional rejuvenation of aged neural stem cells by Plagl2 and anti-Dyrk1a activity

  Takashi Kaise; Masahiro Fukui; Risa Sueda; Wenhui Piao; Mayumi Yamada; Taeko Kobayashi; Itaru Imayoshi; Ryoichiro Kageyama

  Genes & Development, 01 Jan. 2022, Peer-reviewed

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• Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module

  Yujin Harada; Mayumi Yamada; Itaru Imayoshi; Ryoichiro Kageyama; Yutaka Suzuki; Takaaki Kuniya; Shohei Furutachi; Daichi Kawaguchi; Yukiko Gotoh

  Nature Communications, 21 Dec. 2021, Peer-reviewed

  
• An Optimized Preparation Method for Long ssDNA Donors to Facilitate Quick Knock-In Mouse Generation.

  Yukiko U Inoue; Yuki Morimoto; Mayumi Yamada; Ryosuke Kaneko; Kazumi Shimaoka; Shinji Oki; Mayuko Hotta; Junko Asami; Eriko Koike; Kei Hori; Mikio Hoshino; Itaru Imayoshi; Takayoshi Inoue

  Cells, 30 Apr. 2021, Peer-reviewed

  
• Optimization of Light-Inducible Gal4/UAS Gene Expression System in Mammalian Cells

  Mayumi Yamada; Shinji C. Nagasaki; Yusuke Suzuki; Yukinori Hirano; Itaru Imayoshi

  iScience, 25 Sep. 2020, Peer-reviewed

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• Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors

  Philip Allan Seymour; Caitlin Alexis Collin; Anuska la Rosa Egeskov-Madsen; Mette Christine Jørgensen; Hiromi Shimojo; Itaru Imayoshi; Kristian Honnens de Lichtenberg; Raphael Kopan; Ryoichiro Kageyama; Palle Serup

  Developmental Cell, 23 Mar. 2020

  
• Cholecystokinin-Expressing Interneurons of the Medial Prefrontal Cortex Mediate Working Memory Retrieval

  Robin Nguyen; Sridevi Venkatesan; Mary Binko; Jee Yoon Bang; Janine D. Cajanding; Chloe Briggs; Derya Sargin; Itaru Imayoshi; Evelyn K. Lambe; Jun Chul Kim

  The Journal of Neuroscience, 11 Mar. 2020

  
• Light-mediated control of Gene expression in mammalian cells

  Mayumi Yamada; Shinji C. Nagasaki; Takeaki Ozawa; Itaru Imayoshi

  Neuroscience Research, Mar. 2020, Corresponding author

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• Light-induced silencing of neural activity in Rosa26 knock-in and BAC transgenic mice conditionally expressing the microbial halorhodopsin eNpHR3

  Itaru Imayoshi; Sawako Tabuchi; Mami Matsumoto; Satsuki Kitano; Hitoshi Miyachi; Ryoichiro Kageyama; Akihiro Yamanaka

  Scientific Reports, 21 Feb. 2020

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• Generation of a MOR‐CreER knock‐in mouse line to study cells and neural circuits involved in mu opioid receptor signaling

  Taro Okunomiya; Hiroyuki Hioki; Chika Nishimura; Satoshi Yawata; Itaru Imayoshi; Ryoichiro Kageyama; Ryosuke Takahashi; Dai Watanabe

  genesis, Jan. 2020

  
• Enhanced lysosomal degradation maintains the quiescent state of neural stem cells

  Taeko Kobayashi; Wenhui Piao; Toshiya Takamura; Hiroshi Kori; Hitoshi Miyachi; Satsuki Kitano; Yumiko Iwamoto; Mayumi Yamada; Itaru Imayoshi; Seiji Shioda; Andrea Ballabio; Ryoichiro Kageyama

  Nature Communications, 29 Nov. 2019

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• Three-dimensional live imaging of Atoh1 reveals the dynamics of hair cell induction and organization in the developing cochlea

  Tomoko Tateya; Susumu Sakamoto; Fumiyoshi Ishidate; Tsuyoshi Hirashima; Itaru Imayoshi; Ryoichiro Kageyama

  Development, 01 Nov. 2019, Peer-reviewed

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• Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice.

  Chowdhury S; Hung CJ; Izawa S; Inutsuka A; Kawamura M; Kawashima T; Bito H; Imayoshi I; Abe M; Sakimura K; Yamanaka A

  eLife, Jun. 2019, Peer-reviewed

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• High Hes1 expression and resultant Ascl1 suppression regulate quiescent vs. active neural stem cells in the adult mouse brain

  Risa Sueda; Itaru Imayoshi; Yukiko Harima; Ryoichiro Kageyama

  Genes & Development, 12 May 2019

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• Light Control of the Tet Gene Expression System in Mammalian Cells

  Mayumi Yamada; Yusuke Suzuki; Shinji C. Nagasaki; Hiroyuki Okuno; Itaru Imayoshi

  Cell Reports, 09 Oct. 2018

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• A Novel Morphological Marker for the Analysis of Molecular Activities at the Single-cell Level

  Ayako Imanishi; Tomokazu Murata; Masaya Sato; Kazuhiro Hotta; Itaru Imayoshi; Michiyuki Matsuda; Kenta Terai

  Cell Structure and Function, 29 Jun. 2018

  
• Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone

  Amelie Perron; Yoshihiro Nishikawa; Jun Iwata; Hiromi Shimojo; Junichiro Takaya; Kumiko Kobayashi; Itaru Imayoshi; Naasson M. Mbenza; Mihoko Takenoya; Ryoichiro Kageyama; Yuzo Kodama; Motonari Uesugi

  Journal of Biological Chemistry, May 2018

  
• Adult-born neurons facilitate olfactory bulb pattern separation during task engagement

  Wankun L Li; Monica W Chu; An Wu; Yusuke Suzuki; Itaru Imayoshi; Takaki Komiyama

  eLife, 13 Mar. 2018

  
• Inhibitory neuron-specific Cre-dependent red fluorescent labeling using VGAT BAC-based transgenic mouse lines with identified transgene integration sites

  Ryosuke Kaneko; Yusuke Takatsuru; Ayako Morita; Izuki Amano; Asahi Haijima; Itaru Imayoshi; Nobuaki Tamamaki; Noriyuki Koibuchi; Masahiko Watanabe; Yuchio Yanagawa

  Journal of Comparative Neurology, 15 Feb. 2018

  
• Network analysis of exploratory behaviors of mice in a spatial learning and memory task

  Yusuke Suzuki; Itaru Imayoshi

  PLOS ONE, 10 Jul. 2017, Peer-reviewed, Corresponding author

  
• Neural stem cells and neuro/gliogenesis in the central nervous system: understanding the structural and functional plasticity of the developing, mature, and diseased brain

  Masahiro Yamaguchi; Tatsunori Seki; Itaru Imayoshi; Nobuaki Tamamaki; Yoshitaka Hayashi; Yoshitaka Tatebayashi; Seiji Hitoshi

  JOURNAL OF PHYSIOLOGICAL SCIENCES, May 2016, Peer-reviewed

  
• In vivo overactivation of the Notch signaling pathway in the developing cochlear epithelium

  Tomoko Tateya; Susumu Sakamoto; Itaru Imayoshi; Ryoichiro Kageyama

  HEARING RESEARCH, Sep. 2015, Peer-reviewed

  
• Real-time imaging of bHLH transcription factors reveals their dynamic control in the multipotency and fate choice of neural stem cells

  Itaru Imayoshi; Fumiyoshi Ishidate; Ryoichiro Kageyama

  Frontiers in Cellular Neuroscience, 04 Aug. 2015, Peer-reviewed

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• Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells

  Shohei Furutachi; Hiroaki Miya; Tomoyuki Watanabe; Hiroki Kawai; Norihiko Yamasaki; Yujin Harada; Itaru Imayoshi; Mark Nelson; Keiichi I. Nakayama; Yusuke Hirabayashi; Yukiko Gotoh

  NATURE NEUROSCIENCE, May 2015, Peer-reviewed

  
• Dynamic expression and roles of Hes factors in neural development

  Ryoichiro Kageyama; Hiromi Shimojo; Itaru Imayoshi

  CELL AND TISSUE RESEARCH, Jan. 2015, Peer-reviewed

  
• Regulation of neural stem cells in the developing and adult brain

  Itaru Imayoshi

  Seikagaku, 2015, Peer-reviewed

  
• 3D Clustering of GABAergic Neurons Enhances Inhibitory Actions on Excitatory Neurons in the Mouse Visual Cortex

  Teppei Ebina; Kazuhiro Sohya; Itaru Imayoshi; Shu-Ting Yin; Rui Kimura; Yuchio Yanagawa; Hiroshi Kameda; Hiroyuki Hioki; Takeshi Kaneko; Tadaharu Tsumoto

  CELL REPORTS, Dec. 2014, Peer-reviewed

  
• The roles and mechanism of ultradian oscillatory expression of the mouse Hes genes

  Yukiko Harima; Itaru Imayoshi; Hiromi Shimojo; Taeko Kobayashi; Ryoichiro Kageyama

  SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, Oct. 2014, Peer-reviewed

  
• Oscillatory control of bHLH factors in neural progenitors

  Itaru Imayoshi; Ryoichiro Kageyama

  TRENDS IN NEUROSCIENCES, Oct. 2014, Peer-reviewed

  
• bHLH Factors in Self-Renewal, Multipotency, and Fate Choice of Neural Progenitor Cells

  Itaru Imayoshi; Ryoichiro Kageyama

  NEURON, Apr. 2014, Peer-reviewed

  
• Continuous Postnatal Neurogenesis Contributes to Formation of the Olfactory Bulb Neural Circuits and Flexible Olfactory Associative Learning

  Masayuki Sakamoto; Nao Ieki; Goichi Miyoshi; Daisuke Mochimaru; Hitoshi Miyachi; Tetsuya Imura; Masahiro Yamaguchi; Gord Fishell; Kensaku Mori; Ryoichiro Kageyama; Itaru Imayoshi

  JOURNAL OF NEUROSCIENCE, Apr. 2014, Peer-reviewed

  
• The functional significance of newly born neurons integrated into olfactory bulb circuits

  Masayuki Sakamoto; Ryoichiro Kageyama; Itaru Imayoshi

  Frontiers in Neuroscience, 2014, Peer-reviewed

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• Oscillatory Control of Factors Determining Multipotency and Fate in Mouse Neural Progenitors

  Itaru Imayoshi; Akihiro Isomura; Yukiko Harima; Kyogo Kawaguchi; Hiroshi Kori; Hitoshi Miyachi; Takahiro Fujiwara; Fumiyoshi Ishidate; Ryoichiro Kageyama

  SCIENCE, Dec. 2013, Peer-reviewed

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• Hes1 and Hes5 regulate vascular remodeling and arterial specification of endothelial cells in brain vascular development

  Masashi Kitagawa; Masato Hojo; Itaru Imayoshi; Masanori Goto; Mitsushige Ando; Toshiyuki Ohtsuka; Ryoichiro Kageyama; Susumu Miyamoto

  Mechanisms of Development, Sep. 2013, Peer-reviewed

  
• Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea

  Tomoko Tateya; Itaru Imayoshi; Ichiro Tateya; Kiyomi Hamaguchi; Hiroko Torii; Juichi Ito; Ryoichiro Kageyama

  DEVELOPMENT, Sep. 2013, Peer-reviewed

  
• Genetic visualization of notch signaling in mammalian neurogenesis

  Itaru Imayoshi; Hiromi Shimojo; Masayuki Sakamoto; Toshiyuki Ohtsuka; Ryoichiro Kageyama

  CELLULAR AND MOLECULAR LIFE SCIENCES, Jun. 2013, Peer-reviewed

  
• Retinoid acid specifies neuronal identity through graded expression of Ascl1

  John Jacob; Jennifer Kong; Steven Moore; Christopher Milton; Noriaki Sasai; Rosa Gonzalez-Quevedo; Javier Terriente; Itaru Imayoshi; Ryoichoro Kageyama; David G. Wilkinson; Bennett G. Novitch; James Briscoe

  Current Biology, 04 Mar. 2013, Peer-reviewed

  
• Amygdala kindling induces nestin expression in the leptomeninges of the neocortex.

  Shogo Ninomiya; Shigeyuki Esumi; Kunimasa Ohta; Takaichi Fukuda; Tetsufumi Ito; Itaru Imayoshi; Ryoichiro Kageyama; Toshio Ikeda; Shigeyoshi Itohara; Nobuaki Tamamaki

  Neuroscience research, Feb. 2013, Peer-reviewed

  
• Light-induced silencing of neural activity in Rosa26 knock-in mice conditionally expressing the microbial halorhodopsin eNpHR2.0

  Itaru Imayoshi; Sawako Tabuchi; Kyoko Hirano; Masayuki Sakamoto; Satsuki Kitano; Hitoshi Miyachi; Akihiro Yamanaka; Ryoichiro Kageyama

  NEUROSCIENCE RESEARCH, Jan. 2013, Peer-reviewed

  
• Erratum: Retinoid acid specifies neuronal identity through graded expression of ascl1 (Current Biology (2013) 23 (412-418))

  J. Jacob; J. Kong; S. Moore; C. Milton; N. Sasai; R. Gonzalez-Quevedo; J. Terriente; I. Imayoshi; R. Kageyama; D.G. Wilkinson; B.G. Novitch; J. Briscoe

  Current Biology, 2013, Peer-reviewed

  
• Neurogenesis in the postnatal and adult brain

  Itaru Imayoshi

  Japanese Journal of Neuropsychopharmacology, Nov. 2012, Peer-reviewed

  
• In vivo evaluation of PhiC31 recombinase activity in transgenic mice

  Itaru Imayoshi; Kyoko Hirano; Satsuki Kitano; Hitoshi Miyachi; Ryoichiro Kageyama

  NEUROSCIENCE RESEARCH, Jun. 2012, Peer-reviewed

  
• A multifunctional teal-fluorescent Rosa26 reporter mouse line for Cre- and Flp-mediated recombination

  Itaru Imayoshi; Kyoko Hirano; Masayuki Sakamoto; Goichi Miyoshi; Tetsuya Imura; Satsuki Kitano; Hitoshi Miyachi; Ryoichiro Kageyama

  NEUROSCIENCE RESEARCH, May 2012, Peer-reviewed

  
• The role of Hes genes in intestinal development, homeostasis and tumor formation

  Taro Ueo; Itaru Imayoshi; Taeko Kobayashi; Toshiyuki Ohtsuka; Hiroshi Seno; Hiroshi Nakase; Tsutomu Chiba; Ryoichiro Kageyama

  DEVELOPMENT, Mar. 2012, Peer-reviewed

  
• The role of neurogenesis in olfaction-dependent behaviors

  Ryoichiro Kageyama; Itaru Imayoshi; Masayuki Sakamoto

  BEHAVIOURAL BRAIN RESEARCH, Feb. 2012, Peer-reviewed

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• Maintenance of neural stem cells in the brain: role of Notch signaling. Stem Cells and Cancer Stem Cells

  Kageyama R; Shimojo H; Ohtsuka T; Imayoshi I

  Therapeutic Applications in Disease and Injury. Vol.4. (Ed. M.A.Hayat) Springer, 2012, 2012, Peer-reviewed

  
• The Role of Notch Signaling in Adult Neurogenesis

  Itaru Imayoshi; Ryoichiro Kageyama

  MOLECULAR NEUROBIOLOGY, Aug. 2011, Peer-reviewed

  
• Continuous neurogenesis in the adult forebrain is required for innate olfactory responses

  Masayuki Sakamoto; Itaru Imayoshi; Toshiyuki Ohtsuka; Masahiro Yamaguchi; Kensaku Mori; Ryoichiro Kageyama

  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, May 2011, Peer-reviewed

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• Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development

  Tomoko Tateya; Itaru Imayoshi; Ichiro Tateya; Juichi Ito; Ryoichiro Kageyama

  DEVELOPMENTAL BIOLOGY, Apr. 2011, Peer-reviewed

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• Genetic methods to identify and manipulate newly born neurons in the adult brain

  Itaru Imayoshi; Masayuki Sakamoto; Ryoichiro Kageyama

  Frontiers in Neuroscience, 2011, Peer-reviewed

  
• Essential Roles of Notch Signaling in Maintenance of Neural Stem Cells in Developing and Adult Brains

  Itaru Imayoshi; Masayuki Sakamoto; Masahiro Yamaguchi; Kensaku Mori; Ryoichiro Kageyama

  JOURNAL OF NEUROSCIENCE, Mar. 2010, Peer-reviewed

  
• Role Roles of Notch-Hes signaling in adult neural stem cells

  Imayoshi I; Kageyama R

  ENP Neural Stem Cell Meeting 、Abbaye des Vaux de Cernay, France 、6 月17 日~6 月19 日2010., 2010, Peer-reviewed

  
• Dynamic regulation of Notch signaling in neural progenitor cells

  Ryoichiro Kageyama; Toshiyuki Ohtsuka; Hiromi Shimojo; Itaru Imayoshi

  CURRENT OPINION IN CELL BIOLOGY, Dec. 2009, Peer-reviewed

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• The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells

  Taeko Kobayashi; Hiroaki Mizuno; Itaru Imayoshi; Chikara Furusawa; Katsuhiko Shirahige; Ryoichiro Kageyama

  GENES & DEVELOPMENT, Aug. 2009, Peer-reviewed

  
• Continuous neurogenesis in the adult brain

  Itaru Imayoshi; Masayuki Sakamoto; Toshiyuki Ohtsuka; Ryoichiro Kageyama

  DEVELOPMENT GROWTH & DIFFERENTIATION, Apr. 2009, Peer-reviewed

  
• Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development

  Tomoko Tateya; Itaru Imayoshi; Ichiro Tateya; Juichi Ito; Ryoichiro Kageyama

  NEUROSCIENCE RESEARCH, 2009, Peer-reviewed

  
• Prdm Proto-Oncogene Transcription Factor Family Expression and Interaction with the Notch-Hes Pathway in Mouse Neurogenesis

  Emi Kinameri; Takashi Inoue; Jun Aruga; Itaru Imayoshi; Ryoichiro Kageyama; Tomomi Shimogori; Adrian W. Moore

  PLOS ONE, Dec. 2008, Peer-reviewed

  
• Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition

  Ryoichiro Kageyama; Toshiyuki Ohtsuka; Hiromi Shimojo; Itaru Imayoshi

  NATURE NEUROSCIENCE, Nov. 2008, Peer-reviewed

  
• Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain

  Itaru Imayoshi; Masayuki Sakamoto; Toshiyuki Ohtsuka; Keizo Takao; Tsuyoshi Miyakawa; Masahiro Yamaguchi; Kensaku Mori; Toshio Ikeda; Shigeyoshi Itohara; Ryoichiro Kageyama

  NATURE NEUROSCIENCE, Oct. 2008, Peer-reviewed

  
• Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline

  Itaru Imayoshi; Tomomi Shimogori; Toshiyuki Ohtsuka; Ryoichiro Kageyama

  DEVELOPMENT, Aug. 2008, Peer-reviewed

  
• Hes1 and Hes5 control the progenitor pool, intermediate lobe specification, and posterior lobe formation in the pituitary development

  Aya Kita; Itaru Imayoshi; Masato Hojo; Masashi Kitagawa; Hiroshi Kokubu; Ryosuke Ohsawa; Toshiyuki Ohtsuka; Ryoichiro Kageyama; Nobuo Hashimoto

  MOLECULAR ENDOCRINOLOGY, Jun. 2007, Peer-reviewed

  
• Functional significance of adult neurogenesis in the mouse brain

  Itaru Imayoshi; Shigeyoshi Itohara; Toshio Ikeda; Ryoichiro Kageyama

  NEUROSCIENCE RESEARCH, 2007, Peer-reviewed

  
• 下垂体発生におけるHes1・Hes5 の機能解析

  喜田亜矢; 今吉格; 北条雅人; 北川雅史; 後藤正憲; 国分寛司; 大津亮介; 大塚俊之; 橋本信夫; 影山龍一郎

  Neuro 2007 、横浜、 2007, 2007, Peer-reviewed

  
• マウス成体脳における神経新生の機能的意義

  今吉格; 糸原重美; 池田敏男; 影山龍一郎

  Neuro 2007 、横浜、2007, 2007, Peer-reviewed

  
• Roles of Hes genes in development of cerebral cortex and choroid plexus

  I. Imayoshi; T. Ohtsuka; R. Kageyama

  INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, Dec. 2006, Peer-reviewed

  
• High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly

  Paolo E. Forni; Claudio Scuoppo; Itaru Imayoshi; Riccardo Taulli; Walter Dastru; Valentina Sala; Ulrich A. K. Betz; Patrizia Muzzi; Daniela Martinuzzi; Alessandro E. Vercelli; Ryoichiro Kageyama; Carola Ponzetto

  JOURNAL OF NEUROSCIENCE, Sep. 2006, Peer-reviewed

  
• Temporal regulation of Cre recombinase activity in neural stem cells

  Imayoshi, I; T Ohtsuka; D Metzger; P Chambon; R Kageyama

  GENESIS, May 2006, Peer-reviewed

  
• Visualization of embryonic neural stem cells using Hes promoters in transgenic mice

  T Ohtsuka; Imayoshi, I; H Shimojo; E Nishi; R Kageyama; SK McConnell

  MOLECULAR AND CELLULAR NEUROSCIENCE, Jan. 2006, Peer-reviewed

  
• Patterning of the dorsal telencephalic midline by bHLH transcriptional factors.

  Imayoshi I; Ohtsuka T; Kageyama R

  日本分子生物学会2006 フォーラム, 名古屋, 2006., 2006, Peer-reviewed

  
• Visualization of embryonic neural stem cells using Hes promoters in transgenic mice.

  Ohtsuka T; Imayoshi I; Kageyama R; McConnell

  15th International Congress of Developmental Biology, Sydney, Australia, 2005., 2005, Peer-reviewed

  

Misc.

• 生後脳・成体脳におけるニューロン新生と神経幹細胞の制御機構

  今吉 格; 山田 真弓

  月刊 細胞, Jun. 2018

  
• 遺伝子発現の光制御技術と神経幹細胞研究への応用

  今吉 格; 鈴木 裕輔

  実験医学, 2018

  
• 遺伝子発現の光制御

  今吉 格; 山田 真弓

  Clinical Neuroscience, 2018

  
• 神経幹細胞の増殖・分化の光制御と生後脳・成体脳ニューロン新生

  今吉 格

  ブレインサイエンス・レビュー 2017, Feb. 2017

  
• The functional significance of postnatal and adult neurogenesis in olfaction and memory

  今吉 格; 鈴木 裕輔

  AROMA RESEARCH, Aug. 2016

  
• 蝸牛感覚上皮発生におけるNotchシグナル活性化の影響

  楯谷 智子; 坂本 進; 今吉 格; 影山 龍一郎

  日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, Dec. 2015

  
• 発生期および成体脳における神経幹細胞の制御メカニズム

  今吉 格

  生化学, 2015

  
• 成体脳神経幹細胞の増殖と分化制御

  今吉 格

  医学のあゆみ, Dec. 2014

  
• 大人の脳の神経幹細胞を光で操作する

  今吉 格

  現代化学, Nov. 2014

  
• 成体脳における神経幹細胞の光操作

  今吉 格

  現代科学, Nov. 2014

  
• 中枢CNP/NPR‐Bシグナルの肥満および脂肪肝形成における役割の検討

  山下唯; 後藤伸子; 勝浦五郎; 宮崎由理; 今吉格; 金本巨哲; 三浦晶子; 八十田明宏; 大日向耕作; 影山龍一郎; 稲垣暢也; 中尾一和

  日本内分泌学会雑誌, Sep. 2014

  
• The functional significance of newly born neurons integrated into olfactory bulb circuits

  Masayuki Sakamoto; Ryoichiro Kageyama; Itaru Imayoshi

  FRONTIERS IN NEUROSCIENCE, May 2014

  Access this misc :

  
• 脂肪肝病態形成における中枢CNP/GC‐Bシグナルの役割―高脂肪食負荷脳特異的GC‐B欠損マウスによる検討

  山下唯; 後藤伸子; 勝浦五郎; 宮崎由理; 今吉格; 金本巨哲; 三浦晶子; 八十田明宏; 大日向耕作; 影山龍一郎; 稲垣暢也; 中尾一和

  日本内分泌学会雑誌, Apr. 2014

  
• オレキシン神経による摂食行動・代謝の統合的機能調節

  犬束歩; LAZARUS M; 冨田江一; 平林真澄; 今吉格; 影山龍一郎; 山中章弘

  日本生理学雑誌, 01 Mar. 2014

  
• 脳の設計図と変化する脳

  今吉 格

  分子精神医学, Jan. 2014

  
• 遺伝子発現の光制御とその応用の可能性

  磯村彰宏; 今吉 格

  細胞工学, Jan. 2014

  
• Stem Cells: From Basic Research to Therapy: Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms. Edited by Federico Calegari & Claudia Waskow. Chapter 9.

  Kageyama, R; Ohtsuka, T; Shimojo, H; Imayoshi, I

  Dynamic Gene Networks in Neural Stem Cell Regulation., 2014

  
• 脳特異的NPR-B欠損マウスにおける内臓脂肪蓄積および脂肪肝進展抑制効果

  山下 唯; 後藤 伸子; 勝浦 五郎; 宮崎 由理; 今吉 格; 金本 巨哲; 三浦 晶子; 八十田 明宏; 荒井 宏司; 細田 公則; 大日向 耕作; 影山 龍一郎; 中尾 一和

  肥満研究, Sep. 2013

  
• 脳特異的NPR‐B欠損マウスの肝臓および内臓脂肪への脂質蓄積抑制効果

  山下唯; 後藤伸子; 勝浦五郎; 宮崎由理; 今吉格; 金本巨哲; 三浦晶子; 八十田明宏; 荒井宏司; 細田公則; 大日向耕作; 影山龍一郎; 中尾一和

  日本内分泌学会雑誌, Sep. 2013

  
• 脳特異的GC‐B deficientマウスの脂肪肝改善作用の検討

  YAMASHITA YUI; GOTO NOBUKO; KATSUURA GORO; OCHI YUKARI; IMAYOSHI ITARU; ARIYASU HIROYUKI; KANEMOTO NAOAKI; MIURA AKIKO; YASODA AKIHIRO; ARAI HIROSHI; KAGEYAMA RYUICHIRO; NAKAO KAZUWA

  日本内分泌学会雑誌, 01 Apr. 2013

  
• 生後脳・成体脳ニューロン新生の精神疾患への関与の解明

  今吉 格

  医科学応用研究財団研究報告, 2013

  
• 生後脳・成体脳におけるニューロン新生と神経幹細胞の制御機構

  今吉 格

  日本神経精神薬理学雑誌, Nov. 2012

  
• 遺伝子改変マウスを用いた神経幹細胞・ニューロンの標識

  今吉格; 影山龍一郎

  イメージンクと光操作, 技術支援講演会, 岡崎,6月7日, 2012, 2012, Peer-reviewed

  
• 成体脳におけるニューロン新生は先天的にプログラムされた匂い応答に必須である

  坂本 雅行; 今吉 格; 影山 龍一郎

  AROMA RESEARCH, Nov. 2011

  
• Regulatory mechanisms of adult neurogenesis from neural stem cells

  Itaru Imayoshi; Masayuki Sakamoto; Kyoko Hirano; Ryoichiro Kageyama

  NEUROSCIENCE RESEARCH, 2011

  
• Hedgehog signaling is needed for development and maintenance of the cochlear sensory epithelium

  Tomoko Tateya; Itaru Imayoshi; Ichiro Tateya; Kiyomi Hamaguchi; Makoto Ishibashi; Juichi Ito; Ryoichiro Kageyama

  NEUROSCIENCE RESEARCH, 2011

  
• GABAergic neuron production in the mouse neocortex induced by amygdala kindling

  Shogo Ninomiya; Tetsufumi Ito; Chiyoko Tanahira; Itaru Imayoshi; Ryoichiro Kageyama; Toshio Ikeda; Shigeyoshi Itohara; Kaori Akashi; Kenji Sakimura; Nobuaki Tamamaki

  NEUROSCIENCE RESEARCH, 2011

  
• Genetic methods to identify and manipulate newly born neurons in the adult brain

  Itaru Imayoshi; Masayuki Sakamoto; Ryoichiro Kageyama

  FRONTIERS IN NEUROSCIENCE, 2011

  
• Requirement of continuous neurogenesis in the adult forebrain for gender-specific activities.

  Sakamoto M; Imayoshi I; Yamaguchi M; Mori K; Kageyama R

  Keystone Symposium ---Adult Neurogenesis, Taos, USA, 1月9日-1月14日, 2011., 2011, Peer-reviewed

  
• 成体脳神経幹細胞からの嗅球新生ニューロン の分化制御機構

  今吉格; 坂本雅行; 平野響子; 影山龍一郎

  第34 回日本神経科学大会, 横浜,9 月14 日-9 月17 日,2011., 2011, Peer-reviewed

  
• ヘッジホック シグナルは蝸牛感覚上皮の発生と維持に必要である

  楯谷智子; 今吉格; 楯谷一郎; 濱口清海; 石橋誠; 伊藤壽一; 影山龍一郎

  第34 回日本神経科学会, 横 浜,9 月14 日-9 月17 日,2011., 2011, Peer-reviewed

  
• Adult Neurogenesis

  Imayoshi I; Kageyama R

  Keystone Symposium, Taos, USA, 1 月9 日-1 月14 日,2011, 2011, Peer-reviewed

  
• 成体脳ニューロン新生の分子メカニズムと機能的意義

  今吉 格; 坂本 雅行; 影山 龍一郎

  実験医学, Mar. 2010

  
• Analysis of newly generated neurons in the accessory olfactory bulb

  Masayuki Sakamoto; Itaru Imayoshi; Masahiro Yamaguchi; Kensaku Mori

  NEUROSCIENCE RESEARCH, 2010

  
• 成体脳神経幹細胞におけるHes1 はNotchHes シグナルの役割

  今吉格; 坂本雅行; 影山龍一郎

  第33 回日本神経科学大会、神戸、9 月2 日~9 月4 日、2010., 2010, Peer-reviewed

  
• 成体脳ニューロン新生と高次脳機能

  今吉 格

  メディカルバイオ, Mar. 2009

  
• Requirement of continuous neurogenesis for the structural and functional integrity of the adult brain

  I. Imayoshi; M. Sakamoto; R. Kageyama

  INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, Dec. 2008

  
• Requirement of continuous neurogenesis for the structural and functional integrity of the adult brain

  Masayuki Sakamoto; Itaru Imayoshi; Toshiyuki Ohtsuka; Ryoichiro Kageyama

  NEUROSCIENCE RESEARCH, 2008

  
• The bHLH transcriptional network regulates the differentiation of Cajal-Retzius and choroid plexus epithelial cells in the mouse telencephalon.

  Imayoshi I; Shimogori T; Kageyama R

  The 4th International Symposium on bHLH genes: Development and Diseases. Kyoto, 2007., 2007, Peer-reviewed

  
• Visualization of Neural Stem Cells in Transgenic Mice Using Hes Promoter

  Toshiyuki Ohtsuka; Itaru Imayoshi; Ryoichiro Kageyama; Susan K. McConnell

  Keystone Symposium C4: Signaling in Vertebrate Organogenesis, Feb. 2004, Peer-reviewed

  

Presentations

• 

  Whole brain imaging by serial tomography with spinning disk confocal microscopy

  今吉 格

  NEURO2024, 25 Jul. 2024, Invited

  
• 動物個性の創発におけるニューロン新生の関与の可能性について

  今吉 格

  未踏探索における個性と集団の役割 Workshops 2024 Feb, 22 Feb. 2024, Invited

  
• 

  光遺伝学ツールを使った神経幹細胞の分化制御メカニズムの解析

  今吉 格

  第46回日本分子生物学会年会, 06 Dec. 2023, 日本分子生物学会, Invited

  
• 

  遺伝子発現の光制御手法を用いた神経幹細胞の制御メカニズムの解析

  今吉 格

  脳神経回路の形成・動作と制御の現在と未来, 23 Aug. 2023, 大阪大学蛋白質研究所, Invited

  
• 

  Analysis of neural stem cell regulatory mechanisms using optogenetics

  Itaru IMAYOSHI

  ASHBi Workshop "Towards engineering embryonic development", 20 Jul. 2023, ASHBi, Invited

  
• 

  神経幹細胞の分化運命決定を担う転写因子発現動態の光遺伝学的解析

  今吉 格

  第157回 Brain Club Seminar, 15 Jun. 2023, Invited

  
• 

  Analysis of neural stem cell regulatory mechanisms using optogenetics

  Itaru Imayoshi

  Neural Development and Diseases, 16 Mar. 2023, Invited

  
• 

  Analysis of neural stem cell regulatory mechanisms using optogenetics

  Itaru Imayoshi

  Cellular Mechanisms of Learning and Memory, 14 Mar. 2023, Invited

  
• 

  Analysis of neural stem cell regulatory mechanisms using optogenetics

  Itaru Imayoshi

  BDR Student-organized seminar 2022, 20 Dec. 2022, Invited

  
• 

  遺伝子発現の光操作を用いた神経幹細胞の制御機構の解析

  今吉 格

  第95回日本生化学会大会, 10 Nov. 2022, Invited

  
• 

  Analysis of neural stem cell regulatory mechanisms using optogenetics

  Itaru Imayoshi

  The 74th Annual Meeting of the Japan Society for Cell Biology, 29 Jun. 2022, Invited

  
• 

  Analysis of neural stem cell regulatory mechanisms using optogenetics

  Itaru Imayoshi

  The International Symposium on Development and and Plasticity of Neural Systems, 16 Mar. 2022, Invited

  
• 遺伝子発現の光操作を用いた神経幹細胞の制御機構の解析

  今吉 格

  慶應医学部新次元開拓セミナー, 03 Mar. 2022, Invited

  
• 微弱発光イメージングによる神経幹細胞の制御機構の解析

  今吉 格

  Olympus Innovation Forum 2021 Online, 16 Dec. 2021, Invited

  
• Analysis of neural stem cell regulatory mechanisms using optogenetics

  Itaru Imayoshi

  The 1st China-Japan-Korea International Meeting (July 28-31, 2021), 31 Jul. 2021, 日本神経科学学会, Invited

  
• Comprehensive and cutting-edge solutions for bioimaging: from high speed superresolution to large scale 3D imaging

  Itaru Imayoshi

  The 44th Annual Meeting of the Japan Neuroscience Society, 30 Jul. 2021, カールツァイス株式会社, Invited

  
• Regulatory mechanism of neural stem cells revealed by optical manipulation of gene expressions

  Itaru Imayoshi

  第11回新潟大学脳研究所共同研究拠点国際シンポジウム, 19 Feb. 2021, Invited

  
• 神経幹細胞の制御メカニズムと生後脳・成体脳ニューロン新生

  今吉 格

  江崎グリコ株式会社, 02 Feb. 2021, Invited

  
• 京都大学Spring Program

  今吉 格

  Kyoto Summer/Spring Program, Feb. 2021

  
• Toward understanding and manipulation of neural bases underlying animal behaviors and psychiatric diseases

  Itaru Imayoshi

  第43回日本分子生物学会年会シンポジウム, 03 Dec. 2020

  
• 京都大学大学院生命科学研究科附属生命動態研究センター「発生・生物細胞・システム生物学コース」

  京都大学大学院生命科学研究科附属生命動態研究センター「発生・生物細胞・システム生物学コース」, Dec. 2020

  
• 

  発生発達期暴露による嗅球神経新生影響～毒性評価としての嗅球利用を探る～

  今吉 格

  第４７回日本毒性学会学術年会, 30 Jun. 2020

  
• ExCELLS若手リトリート

  今吉 格

  ExCELLS若手リトリート, Feb. 2020

  
• Chemistry For Neuroscience

  今吉 格

  Chemistry For Neuroscience, Dec. 2019

  
• HFSPを始めとする国際・学際的研究グラントへの挑戦

  今吉 格

  HFSPを始めとする国際・学際的研究グラントへの挑戦, Dec. 2019

  
• 第４回個性創発脳領域会議

  今吉 格

  平成２８年度採択新学術領域「個性」創発脳 第４回領域会議, 01 Aug. 2019

  
• AMED再生医療研究交流会

  今吉 格

  AMED再生医療研究交流会, Aug. 2019

  
• Regulation of neural stem cells and neurogenesis in the mouse postnatal brain

  Itaru Imayoshi

  第21回生命科学研究科シンポジウム, 04 Jul. 2019

  
• AMED革新脳後期キックオフシンポジウム

  今吉 格

  平成31年（令和元年）度 「革新的技術による脳機能ネットワークの全容解明プロジェクト」, Jul. 2019

  
• 第15回成体脳ニューロン新生懇談会

  今吉 格

  第15回成体脳ニューロン新生懇談会, Feb. 2019

  
• 第41回日本分子生物学会年会

  今吉 格

  第41回日本分子生物学会年会, Nov. 2018

  
• 大阪大学・蛋白研セミナー：高次脳機能の神経回路機構

  今吉 格

  Nov. 2018

  
• Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expression(2018)

  Itaru Imayoshi

  MPFI-JST(PRESTO) Joint Workshop on Nueroscience and Single Cell Analysis, 30 Oct. 2018

  
• Functional significance of neurogenesis in the postnatal/adult brain

  Itaru Imayoshi

  第40回日本神経化学・日本生物的精神医学会シンポジウム, 08 Sep. 2018

  
• Adult-born neurons facilitate olfactory bulb pattern separation during task engagement

  Itaru Imayoshi

  京都大学大学院生命科学研究科附属生命動態研究センター「発生・生物細胞・システム生物学コース」, 01 Aug. 2018

  
• 

  Functional significance of neurogenesis in the adult brain

  Itaru Imayoshi

  第20回生命科学研究科シンポジウム, 12 Jul. 2018

  
• 

  Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expression(2018)

  今吉 格

  第16回 幹細胞シンポジウム, 02 Jun. 2018, Invited

  
• AMED再生医療実現拠点ネットワークプログラム（幹細胞・再生医学イノベーション創出プログラム）平成30年度事業内交流会

  今吉 格

  AMED再生医療実現拠点ネットワークプログラム（幹細胞・再生医学イノベーション創出プログラム）平成30年度事業内交流会, Jun. 2018

  
• Toward understanding brain development, maturation, and plasticity

  Itaru Imayoshi

  16th International Student Seminar, 2018, Invited

  
• 神戸大学講演

  今吉 格

  神戸大学, Mar. 2018, Invited

  
• 第三回 京都皮膚基礎研究会講演

  今吉 格

  第三回 京都皮膚基礎研究会, Mar. 2018, Invited

  
• 第一回 武田神経科学シンポジウム講演

  今吉 格

  第一回 武田神経科学シンポジウム, Mar. 2018, Invited

  
• 遺伝子発現の光制御システムを用いた神経幹細胞の制御機構の解析

  今吉 格

  第1回 これからの神経回路研究の会, 2018, Invited

  
• Regulatory mechanism of neural stem cells revealed by optical manipulation of gene expressions(ConBio2017)

  Itaru Imayoshi

  ConBio2017シンポジウム, 2017, Invited

  
• Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions.(NTU)

  Itaru Imayoshi

  国立台湾大学(NTU), 2017, Invited

  
• Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions(2017)

  今吉 格

  第24回 日本時間生物学会学術大会シンポジウム, 2017, Invited

  
• 組織レベルで細胞機能を制御する

  今吉 格

  細胞を創る研究会10.0 シンポジウム, 2017, Invited

  
• 革新的新技術がもたらす脳神経系の発生・発達機構の理解と新展開

  今吉 格

  第40回 日本神経科学大会 シンポジウム, 2017, Invited

  
• 生後脳・成体脳におけるニューロン新生(2017)

  今吉 格

  第40回 日本神経科学大会 ジョセフ・アルトマン記念発達神経科学賞受賞記念講演, 2017, Invited

  
• Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions

  Itaru Imayoshi

  第12回 上原国際シンポジウム「Meke Life Visible」シンポジウム, 2017, Invited

  
• 遺伝子発現の光操作技術と幹細胞研究への応用

  今吉 格

  第64回 日本実験動物学会総会シンポジウム, 2017, Invited

  
• Impairment of the hippocampal postnatal neurogenesis and its involvement in the neurodevelopmental disorder

  Itaru Imayoshi

  Neuroscience2016 第39回日本神経科学大会シンポジウム, 2016, Invited

  
• 9th IBRO World Congress on Neuroscience - IBRO201シンポジウム

  今吉 格

  9th IBRO World Congress on Neuroscience - IBRO201シンポジウム, 2016, Invited

  
• ISDN2016 (International society of developmental neuroscience congress 2016)シンポジウム

  今吉 格

  ISDN2016 (International society of developmental neuroscience congress 2016)シンポジウム, 2016, Invited

  
• 大阪大学・医学系研究科／生命機能研究科講演

  今吉 格

  大阪大学・医学系研究科／生命機能研究科, 2015, Invited

  
• 京都大学大学院医学研究科講演(2)

  今吉 格

  京都大学大学院医学研究科, 2015, Invited

  
• 滋賀医科大学・分子神経科学研究センター国際シンポジウム

  今吉 格

  滋賀医科大学・分子神経科学研究センター国際シンポジウム, 2015, Invited

  
• 9th IBRO World Congress on Neuroscience

  今吉 格

  9th IBRO World Congress on Neuroscience, 2015, Invited

  
• 京都大学大学院医学研究科講演

  今吉 格

  京都大学大学院医学研究科, 2015, Invited

  
• Oscillatory Expression of bHLH Transcriptional Factors in Neural Stem Cells(2014)

  Itaru Imayoshi

  第120回日本解剖学会総会･全国学術集会・第92回日本生理学会大会 合同大会シンポジウム, 2014, Invited

  
• bHLH 型転写因子の発現振動のイメージングから明らかになる神経幹細胞の自己複製能と 多分化能の制御機構

  今吉 格

  第37回日本分子生物学会年会・Zeissランチョンセミナー, 2014, Invited

  
• 成体脳における神経幹細胞の光操作

  今吉 格

  第６回 ドイツ・イノベーション・アワード, 2014, Invited

  
• 第７回神経発生討論会・特別講演

  今吉 格

  第７回神経発生討論会, 2014, Invited

  
• 再生医療研究における長時間ライブセルイメージング ‐3D浮遊培養、オプトジェネティクスを例に‐

  今吉 格

  第１３回 日本再生医療学会総会・オリンパスランチョンセミナー, 2013, Invited

  
• Oscillatory Expression of bHLH Transcriptional Factors in Neural Stem Cells(Neuro2013)

  今吉 格

  Neuro2013・シンポジウム, 2013, Invited

  
• Oscillatory Expression of bHLH Transcriptional Factors in Neural Stem Cells(Neurogenesis2013)

  今吉 格

  アブカムNeurogenesis2013 at Matsushima, 2013, Invited

  
• 脳神経系の形成過程における神経幹細胞の増殖・分化制御

  今吉 格

  第35回日本分子生物学会年会にてワークショップ, 2012, Invited

  
• 理化学研究所・発生再生科学総合研究センター(CDB)

  今吉 格

  理化学研究所・発生再生科学総合研究センター(CDB), 2012, Invited

  
• Section of Neurobiology and Department of Neurosciences, UCSD

  Itaru Imayoshi

  Section of Neurobiology and Department of Neurosciences, UCSD, 2012, Invited

  
• Oscillatory expression of bHLH transcriptional factors in neural stem cells

  Itaru Imayoshi

  New York University School of Medicine, 2012, Invited

  
• 新学術領域研究「神経細胞の多様性と大脳新皮質の構築」技術講習会

  今吉 格

  新学術領域研究「神経細胞の多様性と大脳新皮質の構築」技術講習会, 2012, Invited

  
• 生後脳・成体脳におけるニューロン新生

  今吉 格

  第52回脳の医学・生物学研究会, 2012, Invited

  
• 第5回神経発生討論会

  今吉 格

  第5回神経発生討論会, 2012, Invited

  
• 成体脳ニューロン新生から見た脳の可塑性

  今吉 格

  第36回白眉セミナー, 2012, Invited

  
• JST戦略的国際科学技術協力推進事業「日本－イスラエル研究交流」 Japan-Israel Progress Seminar

  今吉 格

  JST戦略的国際科学技術協力推進事業「日本－イスラエル研究交流」 Japan-Israel Progress Seminar, 2011, Invited

  
• 成体脳神経幹細胞からの嗅球新生ニューロンの分化制御機構

  今吉 格

  第３４回日本神経科学大会シンポジウム, 2011, Invited

  
• 生後脳・成体脳におけるニューロン新生

  今吉 格

  生理学研究所研究会 シナプス可塑性の分子細胞基盤, 2011, Invited

  
• Regulatory Mechanisms of Adult Neurogenesis from Neural Stem Cells

  Itaru Imayoshi

  アブカムNeurogenesis2011 in Kobe, 2011, Invited

  
• 熊本大学GCOE＋発生医学研究所共催サマーリトリートセミナー

  今吉 格

  熊本大学GCOE＋発生医学研究所共催サマーリトリートセミナー, 2010, Invited

  
• 脳科学におけるヒト研究と動物研究のクロスオーバー

  今吉 格

  Neuro2010サテライトシンポジウム「文部科学省関連脳科学研究事業合同ワークショップ」, 2010, Invited

  
• bHLH型転写因子の発現振動による神経幹細胞の自己複製能と多分化能の制御 およびその光操作

  今吉 格

  第７回成体脳ニューロン新生懇談会, 2009, Invited

  
• Long-term labeling and ablation reveal requirement of continuous neurogenesis for the structural and functional integrity of the adult forebrain

  Itaru Imayoshi

  日本発生生物学会第４1回大会シンポジウム, 2008

  
• マウス成体脳における継続的なニューロン新生の役割

  今吉 格

  東北大学脳科学GCOE・第10 回若手フォーラム, 2008, Invited

  
• Functional significance of adult neurogenesis in the mouse brain

  Itaru Imayoshi

  東京大学堀場国際会議大130周年記念事業 コーンバーグファミーリーシンポジウム, 2007, Invited

  
• 

  Roles of postnatal and adult neurogenesis in brain development and maturation

  Itaru Imayoshi

  The 80th Fujihara Seminar, 30 Aug. 2021, Invited

  

Books and Other Publications

• Regulatory Mechanism of Neural Progenitor Cells Revealed by Optical Manipulation of Gene Expressions

  Itaru Imayoshi; Mayumi Yamada; Yusuke Suzuki, Joint work, Make Life Visible pp 9-11

  Springer Nature, 02 Oct. 2019

  
• Stem Cells: From Basic Research to Therapy: Basic Stem Cell Biology, Tissue Formation during Development, and Model Organisms.

  Kageyama, R; Ohtsuka, T; Shimojo, H; Imayoshi, I, 258-276

  CRC Press 2014, 2014, Not refereed

  
• 個性学入門 : 個性創発の科学

  保前 文高; 大隅 典子, III.個性学の展開 11 個性の発生

  朝倉書店, 01 Aug. 2021

  Find Kyoto University's collection of books :

  

Industrial Property Rights

• 特願2013-193582, 幹細胞の増殖と分化の光遺伝学的制御方法

  影山龍一郎; 磯村彰宏; 今吉格

  
• 特願2018-163617, Cry2-CIB1システムを用いたTetシステムの光制御手法

  今吉格; 山田真弓; 鈴木裕輔

  

Awards

• 24 Dec. 2009

  第26回井上研究奨励賞
• 第６回 ドイツ・イノベーション・アワード「ゴットフリード・ワグネル賞2014」最優秀賞
• ２０１５年度 日本神経科学学会奨励賞
• 19 Apr. 2016

  文部科学省, 平成28年度 文部科学大臣表彰・若手科学者賞
• 03 Nov. 2016

  和歌山県橋本市, 和歌山県橋本市文化奨励賞
• 21 Jul. 2017

  日本神経科学学会, 第1回 ジョセフ・アルトマン記念発達神経科学賞

Media Coverage

• 刻まれた記憶「光」に

  読売新聞社, 読売新聞, 夕刊１１ページ, 10 Dec. 2020, Paper

  
• 京都大学、JST、遺伝子のスイッチを「光」と「薬剤」で制御できる新技術を開発～発生・幹細胞・神経科学研究への貢献に期待～

  株式会社 日経BP, 日経バイオテク, 11 Oct. 2018

  
• 脳の神経幹細胞 光で増殖を制御

  朝日新聞社, 朝日新聞, ミチをひらく, 08 Mar. 2018

  
• The Link between Emotions and the Sense of Smell

  NHKワールド, Science View, 02 Sep. 2014

  
• こころを動かす 嗅覚

  NHK, サイエンスZERO, 26 Jun. 2010

  

External funds: Kakenhi

• 神経幹細胞の光操作を用いた生後脳ニューロン新生の機能的意義の全脳レベルでの解析

  Grant-in-Aid for Scientific Research (B)

  Basic Section 44020:Developmental biology-related

  Kyoto University

  今吉 格

  From 01 Apr. 2021, To 31 Mar. 2024, Granted

  神経幹細胞;ニューロン新生;光遺伝学;神経発生;神経可塑性;転写因子;全脳イメージング;海馬;記憶;学習

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21H02485/
• Regulatory mechanism of neural stem cells revealed by optical manipulation of gene expressions

  Grant-in-Aid for Scientific Research (B)

  Basic Section 44020:Developmental biology-related

  Kyoto University

  Itaru Imayoshi

  From 01 Apr. 2018, To 31 Mar. 2021, Project Closed

  神経幹細胞;ニューロン新生;光遺伝学;転写因子;海馬;嗅覚;神経発生;神経再生;ライブイメージング;休眠;細胞分化;神経新生;遺伝子発現

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18H02449/
• Building an international data-sharing platform towards integrated understanding of the "individuality" within the brain system

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Complex systems

  Tohoku University

  Noriko OSUMI

  From 30 Jun. 2016, To 31 Mar. 2022, Project Closed

  「個性」;データシェアリング;オープンサイエンス;融合研究;学際研究;脳科学;基盤;社会脳科学;脳計測科学;脳科学　基盤;社会脳科学　脳計測科学;基盤・社会脳科学;個性;神経基盤

  https://kaken.nii.ac.jp/grant/KAKENHI-INTERNATIONAL-16K21734/
• Individuality caused by postnatal neurogenesis

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Complex systems

  Kyoto University

  Itaru Imayoshi

  From 30 Jun. 2016, To 31 Mar. 2021, Project Closed

  個性創発;ニューロン新生;神経幹細胞;光遺伝学;個性;生後脳ニューロン新生;神経神経;神経発生;神経再生;神経発達;海馬;嗅球;可塑性;神経可塑性

  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-16H06529/
• Integrative Research toward Elucidation of Generative Brain Systems for Individuality

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Complex systems

  Tohoku University

  Noriko Osumi

  From 30 Jun. 2016, To 31 Mar. 2021, Project Closed

  個性;パーソナリティ;脳内基盤;動物モデル;発生発達過程;多様性;数理モデル;データシェアリングプラットフォーム;脳科学;基盤;社会脳科学;脳計測科学;基板・社会脳科学;脳科学　基盤;社会脳科学　脳計測科学;基盤・社会脳科学;神経基盤

  https://kaken.nii.ac.jp/grant/KAKENHI-ORGANIZER-16H06524/
• 遺伝子発現の光操作を可能にする機能性分子の開発

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  今吉 格

  From 01 Apr. 2016, To 31 Mar. 2017, Discontinued

  光操作;イメージング;光遺伝学;遺伝子発現;細胞;シグナル伝達

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-16H01424/
• Adult-born neurons facilitate olfactory bulb pattern separation during task engagement

  Grant-in-Aid for Young Scientists (A)

  Kyoto University

  Itaru Imayoshi

  From 01 Apr. 2015, To 31 Mar. 2018, Project Closed

  ニューロン新生;神経幹細胞;嗅球;海馬;神経新生;嗅覚;神経可塑性;神経発生;可塑性

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15H05570/
• 光遺伝学を用いた構成的アプローチによる細胞競合現象の解析

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  今吉 格

  From 01 Apr. 2015, To 31 Mar. 2017, Discontinued

  細胞競合;光遺伝学;光操作;幹細胞;がん;Notchシグナル

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-15H01489/
• Application of the photo-activatable transcriptional factor to neural circuit study

  Grant-in-Aid for Challenging Exploratory Research

  Kyoto University

  Itaru IMAYOSHI

  From 01 Apr. 2014, To 31 Mar. 2015, Project Closed

  光応答性転写因子;ニューロン;神経幹細胞

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26640011/
• 新規光遺伝学を用いたオリゴデンドロサイト前駆細胞の分化制御と再生医療への応用

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  Kyoto University

  今吉 格

  From 01 Apr. 2014, To 31 Mar. 2016, Project Closed

  オリゴデンドロサイト;神経発生;神経再生

  https://kaken.nii.ac.jp/grant/KAKENHI-PUBLICLY-26117511/
• Identification of an embryonic origin of adult neural stem cells

  Grant-in-Aid for Research Activity Start-up

  The University of Tokyo

  Shohei FURUTACHI

  From 30 Aug. 2013, To 31 Mar. 2015, Project Closed

  神経幹細胞;細胞分裂;起源;p57;細胞周期

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25891008/
• Synaptic connection of newborn neurons in the adult brain

  Grant-in-Aid for Young Scientists (A)

  Kyoto University

  Itaru IMAYOSHI

  From 01 Apr. 2012, To 31 Mar. 2015, Project Closed

  ニューロン新生;神経幹細胞;海馬;嗅球

  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24680035/
• Mechanisms underlying cell type diversity in the mouse neocortex

  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  Biological Sciences

  The University of Tokyo

  Yukiko Gotoh

  From 01 Apr. 2010, To 31 Mar. 2016, Project Closed

  ニューロンサブタイプ;クロマチン状態;神経幹細胞;ニューロン;上皮間葉転換;Scratch

  https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-22123003/

External funds: others

• 成体脳ニューロン新生の機能的意義

  科学技術振興機構

  From 2011, To 2011
• 三次元組織中における単一細胞レベルでの遺伝子発現動態操作法の開発と応用

  戦略的創造研究推進事業　さきがけ

  From 01 Oct. 2014, To 31 Mar. 2018

  今吉　格
• 光操作技術を用いた神経幹細胞の新規分化制御法の開発

  再生医療実現拠点ネットワークプログラム 幹細胞・再生医学イノベーション創出プログラム

  From 23 May 2018

  今吉　格

Education

Teaching subject(s)

• From 01 Apr. 2024, To 31 Mar. 2025

  Mathematical, Statistical and Computational Biology for Expe rimental Biologists

  M344, Year-long, Institute for Liberal Arts and Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Frontier in Life Sciences

  M213, Fall, Institute for Liberal Arts and Sciences, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Frontier in Life Sciences

  5003, Fall, Graduate School of Biostudies, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Cellular & Molecular Mechanisms in Neural Development and Regeneration

  1035, Spring, Graduate School of Biostudies, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Mathematical, Statistical and Computational Biology for Experimental Biologists

  1034, Year-long, Graduate School of Biostudies, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Course in Multicellular Network

  1030, Spring, Graduate School of Biostudies, 1
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminar on Molecular Cell Biology

  9243, Year-long, Faculty of Integrated Human Studies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Studies of Biology A

  9269, Spring, Faculty of Integrated Human Studies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Studies of Biology B

  9270, Fall, Faculty of Integrated Human Studies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Experiments in Systemic Life Sciences

  5013, Spring, Graduate School of Biostudies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Advanced Experiments in Systemic Life Sciences

  5013, Fall, Graduate School of Biostudies, 4
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar B

  2007, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar A

  2006, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar A

  2006, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar B

  2007, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar D

  2009, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar C

  2008, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar C

  2008, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Experimental Course and Seminar D

  2009, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminars on Natural Sciences IIB

  9260, Fall, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminars on Natural Sciences IIA

  9259, Spring, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Seminars on Natural Sciences I

  9258, Fall, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Cell Biology A

  9120, Spring, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Introduction to Natural Sciences A

  0074, Spring, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2024, To 31 Mar. 2025

  Fundamentals for Transdisciplinary Research 10

  KK11, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Mathematical, Statistical and Computational Biology for Experimental Biologists

  1034, Year-long, Graduate School of Biostudies, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Course in Multicellular Network

  1030, Fall, Graduate School of Biostudies, 1
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar C

  2008, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar C

  2008, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar B

  2007, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar D

  2009, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar D

  2009, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar B

  2007, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar A

  2006, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Experimental Course and Seminar A

  2006, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2023, To 31 Mar. 2024

  Studies of Biology

  9153, Year-long, Faculty of Integrated Human Studies, 8
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Experiments in Systemic Life Sciences

  5013, Spring, Graduate School of Biostudies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Advanced Experiments in Systemic Life Sciences

  5013, Fall, Graduate School of Biostudies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminar on Molecular Cell Biology

  9243, Year-long, Faculty of Integrated Human Studies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Molecular Cell Biology

  9139, Year-long, Faculty of Integrated Human Studies, 4
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminars on Natural Sciences IIA

  9259, Spring, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminars on Natural Sciences I

  9258, Fall, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Cell Biology A

  9120, Spring, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Seminars on Natural Sciences IIB

  9260, Fall, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Introduction to Science A

  0072, Spring, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2023, To 31 Mar. 2024

  Fundamentals for Transdisciplinary Research 10

  KK11, Spring, Graduate School of Human and Environmental Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Introduction to Science A

  0072, Spring, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar B

  2007, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminars on Natural Sciences I

  9258, Fall, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Course in Multicellular Network

  1030, Spring, Graduate School of Biostudies, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar C

  2008, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar A

  2006, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Experiments in Systemic Life Sciences

  5013, Fall, Graduate School of Biostudies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Advanced Experiments in Systemic Life Sciences

  5013, Spring, Graduate School of Biostudies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminars on Natural Sciences IIB

  9260, Fall, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Cell Biology A

  9120, Spring, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar D

  2009, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar B

  2007, Spring, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminar on Molecular Cell Biology

  9243, Year-long, Faculty of Integrated Human Studies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar A

  2006, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar D

  2009, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Seminars on Natural Sciences IIA

  9259, Spring, Faculty of Integrated Human Studies, 2
• From 01 Apr. 2022, To 31 Mar. 2023

  Cellular & Molecular Mechanisms in Neural Development and Regeneration

  1035, Spring, Graduate School of Biostudies, 1
• From 01 Apr. 2022, To 31 Mar. 2023

  Studies of Biology

  9153, Year-long, Faculty of Integrated Human Studies, 8
• From 01 Apr. 2022, To 31 Mar. 2023

  Molecular Cell Biology

  9139, Year-long, Faculty of Integrated Human Studies, 4
• From 01 Apr. 2022, To 31 Mar. 2023

  Experimental Course and Seminar C

  2008, Fall, Graduate School of Biostudies, 5
• From 01 Apr. 2022, To 31 Mar. 2023

  Mathematical, Statistical and Computational Biology for Experimental Biologists

  1034, Year-long, Graduate School of Biostudies, 1
• From Apr. 2017, To Mar. 2018

  Advanced Course in Multicellular Network

  Spring, 生命科学研究科
• From Apr. 2017, To Mar. 2018

  Mathematical, Statistical and Computational Biology for Experimental Biologists

  Year-long, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Course in Multicellular Network

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Mathematical, Statistical and Computational Biology for Experimental Biologists

  Year-long, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar A

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar A

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar B

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar B

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar C

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar C

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar D

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar D

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2018, To Mar. 2019

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Course in Multicellular Network

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Mathematical, Statistical and Computational Biology for Experimental Biologists

  Year-long, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar A

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar A

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar B

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar B

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar C

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar C

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar D

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar D

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Experiments in Systemic Life Sciences

  Spring, 生命科学研究科
• From Apr. 2019, To Mar. 2020

  Advanced Experiments in Systemic Life Sciences

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Cellular & Molecular Mechanisms in Neural Development and Regeneration

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Course in Multicellular Network

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Mathematical, Statistical and Computational Biology for Experimental Biologists

  Year-long, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Introduction to Biology and Life Science

  Spring, 全学共通科目
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Experiments in Integrated Life Sciences

  Spring, 生命科学研究科
• From Apr. 2020, To Mar. 2021

  Advanced Experiments in Integrated Life Sciences

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Course in Multicellular Network

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Mathematical, Statistical and Computational Biology for Experimental Biologists

  Year-long, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Experimental Course and Seminar

  Fall, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Experiments in Integrated Life Sciences

  Spring, 生命科学研究科
• From Apr. 2021, To Mar. 2022

  Advanced Experiments in Integrated Life Sciences

  Fall, 生命科学研究科

Participation in PhD Defense

• 数理モデリングを用いた予測符号化に基づく免疫記憶形成によって実現される抗原の有害/無害識別メカニズムの解明

  YOSHIDO KANA, Graduate School of Biostudies, Sub-chief Examiner

  25 Mar. 2024
• 細胞内リボソームタンパク質レベルの恒常性制御機構の遺伝学的解析

  KITAMURA DAIKI, Graduate School of Biostudies, Sub-chief Examiner

  25 Mar. 2024
• バーンズ迷路における空間スケールがマウスの空間学習に与える影響

  TACHIKI YUTO, Graduate School of Biostudies, Chief Examiner

  25 Mar. 2024
• Belly roll: an Ly6 protein regulating nociceptive escape behaviors by modulating peptidergic interneuron excitability in Drosophila melanogaster

  LI, Kai, Graduate School of Biostudies, Sub-chief Examiner

  25 Sep. 2023
• Common features of neural progenitor cells and cortical organization revealed by single cell transcriptome analyses of ferret cortical development

  MERVE BILGIC, Graduate School of Biostudies, Sub-chief Examiner

  24 Nov. 2023
• Regulation of antiviral responses by RIG-I dissociation from dsRNA

  Jung Hyun Im, Graduate School of Biostudies, Sub-chief Examiner

  24 Nov. 2023
• Hes1による発現動態依存的な細胞増殖制御機構の解明

  MAEDA YUKI, Graduate School of Biostudies, Chief Examiner

  24 Nov. 2023
• 栄養依存的な神経突起発達を調節する組織間シグナル伝達の研究

  KANAOKA YASUTETSU, Graduate School of Biostudies, Sub-chief Examiner

  23 Mar. 2023
• 深部生体イメージングを目指したヘム代謝改変による近赤外蛍光タンパク質の高輝度化

  KOBACHI KENJU, Graduate School of Biostudies, Sub-chief Examiner

  23 Mar. 2023
• Epitranscriptomic mediators of environmental impacts on mouse behaviours

  SUKEGAWA MOMOE, Graduate School of Biostudies, Sub-chief Examiner

  23 Mar. 2023
• 青色光作動性 Gal4 転写因子と近赤外光作動性 Tet 転写因子の哺乳類細胞における機能向上とその応用

  NAGASAKI SHINJI, Graduate School of Biostudies, Chief Examiner

  23 Mar. 2023
• MDA5-mediated type I interferonopathy mouse model displays lethal response to immune stimulation

  FRANCINE LIANNE C. EMRALINO, Graduate School of Biostudies, Sub-chief Examiner

  23 Jan. 2023
• 画像データに基づく上皮組織力学のモデル構築およびパラメータ推定法

  OGITA GOSHI, Graduate School of Biostudies, Sub-chief Examiner

  26 Sep. 2022
• Development of fast-dissociating recombinant antibodies for high-density multiplexed IRIS super-resolution microscopy

  ZHANG QIANLI, Graduate School of Biostudies, Sub-chief Examiner

  24 Nov. 2022
• Investigation of Innate Immune Responses in Eptesicus Bat Cells via Comprehensive Analysis

  LIN, HSIEN-HEN, Graduate School of Biostudies, Sub-chief Examiner

  23 Mar. 2022
• マウス側脳室脈絡叢からのSonic hedgehogの分泌が側脳室脈絡叢の肥大と大脳新皮質表面積の拡大をもたらす

  KINOSHITA AKIRA, Graduate School of Biostudies, Chief Examiner

  23 Mar. 2022
• 数理モデル解析による上皮組織及び細胞の化学力学応答の解明

  ASAKURA YOSHIFUMI, Graduate School of Biostudies, Sub-chief Examiner

  24 Sep. 2021
• 神経幹細胞活性化と細胞分化におけるbHLH型転写因子Ascl１の発現動態と機能の解析

  SUEDA RISA, Graduate School of Biostudies, Chief Examiner

  24 Sep. 2021

Part-time lecturer

• From 01 May 2024, To 31 Mar. 2025

  筑波大学
• From 01 Apr. 2021, To 31 Mar. 2022

  東京大学, 大学院医学系研究科

Administration

School management (title, position)

• From 01 Apr. 2024, To 31 Mar. 2025

  国際高等教育院 企画評価専門委員会 生物学部会
• From 01 Apr. 2023, To 31 Mar. 2024

  国際高等教育院 企画評価専門委員会 生物学部会 委員
• From 01 Apr. 2022, To 31 Mar. 2023

  国際高等教育院 企画評価専門委員会 生物学部会 委員

Faculty management (title, position)

• From 01 Apr. 2023

  広報委員会
• From 01 Oct. 2022

  人材育成企画室
• From 01 Apr. 2023

  自己評価委員会
• From 01 Apr. 2019

  国際教育委員会委員
• From 01 Apr. 2019, To 31 Mar. 2021

  改善委員会委員
• From 01 Apr. 2019, To 31 Mar. 2021

  生命科学研究科同窓会　役員
• From 01 Apr. 2019, To 31 Mar. 2020

  男女共同参画推進アクションプラン推進委員会委員
• From 01 Nov. 2019

  将来像検討委員会　　委員
• From 01 Apr. 2020, To 31 Mar. 2021

  高次生命科学専攻専攻長
• From 01 Apr. 2021, To 31 Mar. 2023

  情報発信・ホームページ委員会　委員
• From 01 Apr. 2020, To 31 Mar. 2021

  放射線障害防止委員会４号

Academic, Social Contribution

Academic Contribution

• 

  成体脳ニューロン新生懇談会

  Planning, management, etc.

  今吉 格, From 29 Oct. 2022, To 29 Oct. 2022

  
• 

  神経回路の多階層イメージングの将来

  Planning, management, etc.

  第４４回日本神経科学大会, From 30 Jul. 2021, To 30 Jul. 2021